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OncoTargets and Therapy
ISSN: 1178-6930
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Archive: Volume 11, 2018

Next-generation sequencing of circulating tumor DNA for detection of gene mutations in lung cancer: implications for precision treatment
Lai J, Du B, Wang Y, Wu R, Yu Z
OncoTargets and Therapy 2018, 11:9111-9116
Published Date: 14 December 2018

Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer
Qiu J, Lin X, Zheng T, Tang X, Hua K
OncoTargets and Therapy 2018, 11:9101-9110
Published Date: 14 December 2018

miRNA-30c can be used as a target in the diagnosis and treatment of osteosarcoma
Sun R, Muheremu A, Hu Y
OncoTargets and Therapy 2018, 11:9091-9099
Published Date: 14 December 2018

Encorafenib/binimetinib for the treatment of BRAF-mutant advanced, unresectable, or metastatic melanoma: design, development, and potential place in therapy
Sun J, Zager JS, Eroglu Z
OncoTargets and Therapy 2018, 11:9081-9089
Published Date: 14 December 2018

Risk factors for lymph node metastasis and the impact of adjuvant chemotherapy on ductal carcinoma in situ with microinvasion: a population-based study
Chen C, Huang S, Huang A, Jia Y, Wang J, Zhang Z, Mao M, Wang L, Zhou J
OncoTargets and Therapy 2018, 11:9071-9080
Published Date: 13 December 2018

The effect of additional chemotherapy on high-risk prostate cancer: a systematic review and meta-analysis
Chen J, Zhang X, Sun G, Zhao J, Liu J, Zhao P, Dai J, Shen P, Zeng H
OncoTargets and Therapy 2018, 11:9061-9070
Published Date: 13 December 2018

Early and late outcomes of bevacizumab plus chemotherapy versus chemotherapy alone as a neoadjuvant treatment in HER2-negative nonmetastatic breast cancer: a meta-analysis of randomized controlled trials
Wei J, Luo Y, Fu D
OncoTargets and Therapy 2018, 11:9049-9059
Published Date: 12 December 2018

Curative effectiveness and safety of osimertinib in the treatment for non-small-cell lung cancer: a meta-analysis of the experimental evidence
Chen P, Chen F, Lei J, Zhou B
OncoTargets and Therapy 2018, 11:9033-9047
Published Date: 12 December 2018

Pseudomyxoma extraperitonei in horseshoe kidney masquerading as renal hilar tumor: a case report
Wang X, Gao X, Wang L, Dai Z, Fan B, Cui H, Liu Z
OncoTargets and Therapy 2018, 11:9027-9032
Published Date: 12 December 2018

microRNA-769 is downregulated in colorectal cancer and inhibits cancer progression by directly targeting cyclin-dependent kinase 1
Wang L, Xu M, Lu P, Zhou F
OncoTargets and Therapy 2018, 11:9013-9025
Published Date: 12 December 2018

A primary retroperitoneal anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with tumor thrombosis
Li J, Tian X, Wang M, Liu W, Guo X, Wang K, Nong L, Wang W, Yang Y
OncoTargets and Therapy 2018, 11:9007-9011
Published Date: 12 December 2018

Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl-2 axis
Zhao H, Han L, Jian Y, Ma Y, Yan W, Chen X, Xu H, Li L
OncoTargets and Therapy 2018, 11:8995-9006
Published Date: 11 December 2018

c.1439delA frameshift deletion mutation in familial adenomatous polyposis

Ma DJ, Wang BS, Yue JB, Li ZJ, Sun YL
OncoTargets and Therapy 2018, 11:8987-8993
Published Date: 11 December 2018

Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells
Li X, Zhu G, Yao X, Wang N, Hu R, Kong Q, Zhou D, Long L, Cai J, Zhou W
OncoTargets and Therapy 2018, 11:8977-8985
Published Date: 11 December 2018

miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1
Yao R, Zheng H, Wu L, Cai P
OncoTargets and Therapy 2018, 11:8965-8976
Published Date: 11 December 2018

MIIP is downregulated in gastric cancer and its forced expression inhibits proliferation and invasion of gastric cancer cells in vitro and in vivo
Sun D, Wang Y, Jiang S, Wang G, Xin Y
OncoTargets and Therapy 2018, 11:8951-8964
Published Date: 11 December 2018

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report
De Carlo E, Schiappacassi M, Urbani M, Doliana R, Baldassarre G, Da Ros V, Santarossa S, Chimienti E, Berto E, Fratino L, Bearz A
OncoTargets and Therapy 2018, 11:8945-8950
Published Date: 10 December 2018

A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1 [Corrigendum]
Zhao XZ, Wu XH
OncoTargets and Therapy 2018, 11:8943-8944
Published Date: 10 December 2018

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms

Ludmir EB, Gutschenritter T, Pinnix CC, Gunther JR, Nastoupil LJ, Khoury JD, Medeiros LJ, Dabaja BS, Milgrom SA
OncoTargets and Therapy 2018, 11:8937-8942
Published Date: 10 December 2018

Osteopontin versus alpha-fetoprotein as a diagnostic marker for hepatocellular carcinoma: a meta-analysis
Sun TT, Tang YR, Sun DW, Bu Q, Li P
OncoTargets and Therapy 2018, 11:8925-8935
Published Date: 10 December 2018

The potential functions of FAM46C in oral squamous cell carcinoma
Zhuang X, Lu M
OncoTargets and Therapy 2018, 11:8915-8923
Published Date: 10 December 2018

Good local tumor control but lethal hemorrhage after apatinib treatment for intractable squamous carcinoma of the floor of the mouth: a case report

Zhu X, Liu M, Lv J, Guo L, Li C, Dong L, Liu B
OncoTargets and Therapy 2018, 11:8909-8913
Published Date: 7 December 2018

Drug–target–disease network analysis of gene–phenotype connectivity for genistein in ovarian cancer
Zhang C, Yang F, Ni S, Teng W, Ning Y
OncoTargets and Therapy 2018, 11:8901-8908
Published Date: 10 December 2018

Predictive value of positron emission tomography for the prognosis of molecularly targeted therapy in solid tumors
Xie X, Chen H, Yang H, Lin H, Zhou S, Shen R, Lu C, Ling L, Lin W, Liao Z
OncoTargets and Therapy 2018, 11:8885-8899
Published Date: 7 December 2018

Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/β-catenin pathway
Tang Z, Cai H, Wang R, Cui Y
OncoTargets and Therapy 2018, 11:8875-8883
Published Date: 7 December 2018

miRNA-19 promotes non-small-cell lung cancer cell proliferation via inhibiting CBX7 expression
Peng X, Guan L, Gao B
OncoTargets and Therapy 2018, 11:8865-8874
Published Date: 7 December 2018

Overexpressing lncRNA SNHG16 inhibited HCC proliferation and chemoresistance by functionally sponging hsa-miR-93
Xu F, Zha G, Wu Y, Cai W, Ao J
OncoTargets and Therapy 2018, 11:8855-8863
Published Date: 7 December 2018

Transcatheter hepatic arterial chemoembolization plus cinobufotalin injection adjuvant therapy for advanced hepatocellular carcinoma: a meta-analysis of 27 trials involving 2,079 patients
Guo N, Miao YY, Sun MZ
OncoTargets and Therapy 2018, 11:8835-8853
Published Date: 7 December 2018

Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells
Pérez-Cárdenas E, Taja-Chayeb L, Trejo-Becerril C, Chanona-Vilchis J, Chávez-Blanco A, Domínguez-Gómez G, Langley E, García-Carrancá A, Dueñas-González A
OncoTargets and Therapy 2018, 11:8823-8833
Published Date: 7 December 2018

TSPAN7 promotes the migration and proliferation of lung cancer cells via epithelial-to-mesenchymal transition
Wang X, Lin M, Zhao J, Zhu S, Xu M, Zhou X
OncoTargets and Therapy 2018, 11:8815-8822
Published Date: 13 December 2018

TRIM37 promotes cell invasion and metastasis by regulating SIP1-mediated epithelial–mesenchymal transition in gastric cancer
Chen D, You X, Pan Y, Liu Q, Cao G
OncoTargets and Therapy 2018, 11:8803-8813
Published Date: 10 December 2018

MicroRNA-486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells
Feng L, Jing L, Han J, Wang G, Liu Y, Zhang X, Wang Y, Wang F, Ma H, Liu Y
OncoTargets and Therapy 2018, 11:8791-8801
Published Date: 6 December 2018

PIWI-like protein 1 upregulation promotes gastric cancer invasion and metastasis
Gao CL, Sun R, Li DH, Gong F
OncoTargets and Therapy 2018, 11:8783-8789
Published Date: 6 December 2018

miR-1 inhibits the proliferation of breast cancer stem cells by targeting EVI-1
Wu L, Wang T, He D, Li X, Jiang Y
OncoTargets and Therapy 2018, 11:8773-8781
Published Date: 6 December 2018

SFRP5 inhibits the migration and invasion of melanoma cells through Wnt signaling pathway
Chen Y, Zou D, Wang N, Tan T, Liu Y, Zhao Q, Pu Y, Thapa RJ, Chen J
OncoTargets and Therapy 2018, 11:8761-8772
Published Date: 6 December 2018

Inhibition of XIAP increases carboplatin sensitivity in ovarian cancer
Zhang Y, Huang F, Luo Q, Wu X, Liu Z, Chen H, Huang Y
OncoTargets and Therapy 2018, 11:8751-8759
Published Date: 5 December 2018

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion
Song S, Li D, Yang C, Yan P, Bai Y, Zhang Y, Hu G, Lin C, Li X
OncoTargets and Therapy 2018, 11:8741-8750
Published Date: 5 December 2018

MALAT1 promotes proliferation, migration, and invasion of MG63 cells by upregulation of TGIF2 via negatively regulating miR-129
Liu K, Zhang YG, Liu L, Yuan QL
OncoTargets and Therapy 2018, 11:8729-8740
Published Date: 4 December 2018

Pathological complete response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with unresectable BRAF V600E-mutant malignant melanoma of the gallbladder
Yu Z, Quiroz E, Shen Y, Jaiyesimi IA
OncoTargets and Therapy 2018, 11:8723-8728
Published Date: 4 December 2018

Development and validation of a prognostic signature for preoperative prediction of overall survival in gastric cancer patients
Zhu M, Wang Q, Luo Z, Liu K, Zhang Z
OncoTargets and Therapy 2018, 11:8711-8722
Published Date: 4 December 2018

Clinical benefit from afatinib in an advanced squamous cell lung carcinoma patient harboring HER2 S310Y mutation: a case report
Gao Y, Zheng AH, Zhu XM, Song J, Xue Q
OncoTargets and Therapy 2018, 11:8705-8710
Published Date: 5 December 2018

MiR-411 suppresses the development of bladder cancer by regulating ZnT1
Liu Y, Liu T, Jin H, Yin L, Yu H, Bi J
OncoTargets and Therapy 2018, 11:8695-8704
Published Date: 4 December 2018

Application of preoperative three-dimensional model design in radioactive particle implantation for advanced pancreatic cancer

Liu Y, Lyu S, Wang X, Wang Y
OncoTargets and Therapy 2018, 11:8685-8693
Published Date: 4 December 2018


Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients


Feldheim J, Kessler AF, Schmitt D, Wilczek L, Linsenmann T, Dahlmann M, Monoranu CM, Ernestus RI, Hagemann C, Löhr M
OncoTargets and Therapy 2018, 11:8673-8684
Published Date: 4 December 2018

A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model
Park S, Kim D, Wu G, Jung H, Park JA, Kwon HJ, Lee Y
OncoTargets and Therapy 2018, 11:8655-8672
Published Date: 3 December 2018

miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3
Guo J, Liu Q, Li Z, Guo H, Bai C, Wang F
OncoTargets and Therapy 2018, 11:8643-8653
Published Date: 3 December 2018

Natural product pectolinarigenin inhibits proliferation, induces apoptosis, and causes G2/M phase arrest of HCC via PI3K/AKT/mTOR/ERK signaling pathway
Wu T, Dong X, Yu D, Shen Z, Yu J, Yan S
OncoTargets and Therapy 2018, 11:8633-8642
Published Date: 3 December 2018

Efficacy and safety of PD1/PDL1 blockades versus docetaxel in patients with pretreated advanced non-small-cell lung cancer: a meta-analysis
Liu J, Zhong Y, Peng S, Zhou X, Gan X
OncoTargets and Therapy 2018, 11:8623-8632
Published Date: 3 December 2018

Efficacy and safety of bevacizumab-based combination therapy for treatment of patients with metastatic colorectal cancer
Xu R, Xu C, Liu C, Cui C, Zhu J
OncoTargets and Therapy 2018, 11:8605-8621
Published Date: 4 December 2018

Intestinal metastasis from breast invasive ductal carcinoma after a long latency: case report and literature review

Liu M, Zhang L, Guo L, Lv J, Shi W, Liu B
OncoTargets and Therapy 2018, 11:8599-8603
Published Date: 3 December 2018

A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
Vinhas R, Lourenço A, Santos S, Lemos M, Ribeiro P, Botelho Sousa A, Baptista PV, Fernandes AR
OncoTargets and Therapy 2018, 11:8589-8598
Published Date: 30 November 2018


Afatinib versus gemcitabine/cisplatin for first-line treatment of Chinese patients with advanced non-small-cell lung cancer harboring EGFR mutations: subgroup analysis of the LUX-Lung 6 trial


Wu YL, Xu CR, Hu CP, Feng J, Lu S, Huang Y, Li W, Hou M, Shi JH, Märten A, Fan J, Peil B, Zhou C
OncoTargets and Therapy 2018, 11:8575-8587
Published Date: 30 November 2018


Afatinib vs erlotinib for second-line treatment of Chinese patients with advanced squamous cell carcinoma of the lung


Lu S, Li W, Zhou C, Hu CP, Qin S, Cheng G, Feng J, Wang J, Cseh A, Peil B, Gibson N, Ehrnrooth E, Zhang L
OncoTargets and Therapy 2018, 11:8565-8573
Published Date: 30 November 2018

Local analgesic effect of a bioadhesive barrier-forming oral liquid in cancer patients with oral mucositis caused by chemotherapy and/or radiotherapy: a randomized multicenter, single-use, positive-controlled, open-label study
Cheng Y, Qin SK, Chen YP, Dong LH, Sun XD, Yu SY, Wu SK
OncoTargets and Therapy 2018, 11:8555-8564
Published Date: 30 November 2018

Vandetanib (ZD6474) induces antiangiogenesis through mTOR–HIF-1 alpha–VEGF signaling axis in breast cancer cells
Li L, Yu J, Jiao S, Wang W, Zhang F, Sun S
OncoTargets and Therapy 2018, 11:8543-8553
Published Date: 29 November 2018

A novel long-sustaining system of apatinib for long-term inhibition of the proliferation of hepatocellular carcinoma cells
Wang YL, Tang ZG
OncoTargets and Therapy 2018, 11:8529-8541
Published Date: 29 November 2018

Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release
Ma Y, Liu X, Ma Q, Liu Y
OncoTargets and Therapy 2018, 11:8517-8528
Published Date: 29 November 2018

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1α
Tang L, Wu J, Cai S, Huang Y, Zhang X, Fu W, Zhuang Q, Li J
OncoTargets and Therapy 2018, 11:8507-8515
Published Date: 29 November 2018

Elevated FAM3C promotes cell epithelial–mesenchymal transition and cell migration in gastric cancer
Shi M, Duan G, Nie S, Shen S, Zou X
OncoTargets and Therapy 2018, 11:8491-8505
Published Date: 5 December 2018

Upregulation of SOX18 in colorectal cancer cells promotes proliferation and correlates with colorectal cancer risk
Miao Z, Deng X, Shuai P, Zeng J
OncoTargets and Therapy 2018, 11:8481-8490
Published Date: 29 November 2018

Overexpression of Mst1 reduces gastric cancer cell viability by repressing the AMPK-Sirt3 pathway and activating mitochondrial fission
Yao S, Yan W
OncoTargets and Therapy 2018, 11:8465-8479
Published Date: 29 November 2018

Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells
Yang Y, Zhu F, Wang Q, Ding Y, Ying R, Zeng L
OncoTargets and Therapy 2018, 11:8455-8463
Published Date: 29 November 2018

MiR-21-5p promotes the progression of non-small-cell lung cancer by regulating the expression of SMAD7
Li X, Wu X
OncoTargets and Therapy 2018, 11:8445-8454
Published Date: 28 November 2018

XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer
Li Q, Ma R, Zhang M
OncoTargets and Therapy 2018, 11:8435-8444
Published Date: 28 November 2018

High expression of uPA related to p38MAPK in esophageal cancer indicates poor prognosis
Liu Q, Li W, Yang S, Liu Z
OncoTargets and Therapy 2018, 11:8427-8434
Published Date: 29 November 2018

Better efficacy of intrapleural infusion of bevacizumab with pemetrexed for malignant pleural effusion mediated from nonsquamous non-small cell lung cancer
Song X, Chen D, Guo J, Kong L, Wang H, Wang Z
OncoTargets and Therapy 2018, 11:8421-8426
Published Date: 27 November 2018

lncRNA FBXL19-AS1 regulates osteosarcoma cell proliferation, migration and invasion by sponging miR-346
Pan RS, He ZX, Ruan WY, Li S, Chen H, Chen ZY, Liu F, Tian XB, Nie YJ
OncoTargets and Therapy 2018, 11:8409-8420
Published Date: 29 November 2018

LncRNA ANCR promotes proliferation and radiation resistance of nasopharyngeal carcinoma by inhibiting PTEN expression
Ma X, Zhou J, Liu J, Wu G, Yu Y, Zhu H, Liu J
OncoTargets and Therapy 2018, 11:8399-8408
Published Date: 27 November 2018

A comparison of fulvestrant plus a targeted agent with fulvestrant alone in hormone receptor-positive advanced breast cancer that progressed on prior endocrine therapy: a meta-analysis
Xu L, Yan N, Li Z, Luo L, Wu X, Liu Q, Xu Y, Cao Y
OncoTargets and Therapy 2018, 11:8389-8398
Published Date: 27 November 2018

Prognostic roles of mRNA expression of peroxiredoxins in lung cancer
Chen L, Huang C, Yang X, Zhang Q, Chen F
OncoTargets and Therapy 2018, 11:8381-8388
Published Date: 27 November 2018

GDF11 restrains tumor growth by promoting apoptosis in pancreatic cancer
Liu Y, Shao L, Chen K, Wang Z, Wang J, Jing W, Hu M
OncoTargets and Therapy 2018, 11:8371-8379
Published Date: 27 November 2018

Is APC hypermethylation a diagnostic biomarker for bladder cancer? A meta-analysis
Han W, Wang Y, Fan J, Wang C
OncoTargets and Therapy 2018, 11:8359-8369
Published Date: 27 November 2018

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells [Corrigendum]
Pan B, Han H, Wu L, Xiong Y, Zhang J, Dong B, Yang Y, Chen J
OncoTargets and Therapy 2018, 11:8357-8358
Published Date: 26 November 2018

TGF-beta 1 levels are associated with lymphocyte percentages in patients with lung cancer treated with radiation therapy
Luo J, Hu S, Wei T, Sun J, Liu N, Wang J
OncoTargets and Therapy 2018, 11:8349-8355
Published Date: 26 November 2018

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma
Jiang Z, Zhai X, Shi B, Luo D, Jin B
OncoTargets and Therapy 2018, 11:8341-8348
Published Date: 23 November 2018

New developments in the treatment of basal cell carcinoma: update on current and emerging treatment options with a focus on vismodegib
Koelblinger P, Lang R
OncoTargets and Therapy 2018, 11:8327-8340
Published Date: 23 November 2018

Prognostic significance of mammary Paget’s disease in Chinese women: a 10 year, population-based, matched cohort study
Zhou H, Lu K, Zheng L, Guo L, Gao Y, Miao X, Chen Z, Wang X
OncoTargets and Therapy 2018, 11:8319-8326
Published Date: 23 November 2018

Associations between the NUDT15 R139C polymorphism and susceptibility to thiopurine-induced leukopenia in Asians: a meta-analysis
Liu Y, Meng Y, Wang L, Liu Z, Li J, Dong W
OncoTargets and Therapy 2018, 11:8309-8317
Published Date: 23 November 2018

Modified FOLFOX6 as a first-line treatment for patients with advanced gastric cancer with massive ascites or inadequate oral intake
Osumi H, Takahari D, Chin K, Ogura M, Ichimura T, Wakatsuki T, Suzuki T, Ota Y, Nakayama I, Ooki A, Suenaga M, Shinozaki E, Yamaguchi K
OncoTargets and Therapy 2018, 11:8301-8307
Published Date: 23 November 2018

Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability
Li M, Yang Y
OncoTargets and Therapy 2018, 11:8293-8299
Published Date: 22 November 2018

The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1
Gagat M, Hałas-Wiśniewska M, Zielińska W, Izdebska M, Grzanka D, Grzanka A
OncoTargets and Therapy 2018, 11:8275-8292
Published Date: 22 November 2018

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage [Corrigendum]
Liu WJ, Yin YB, Sun JY, Feng S, Ma JK, Fu XY, Hou YJ, Yang MF, Sun BL, Fan CD
OncoTargets and Therapy 2018, 11:8273-8274
Published Date: 22 November 2018

The return of gemtuzumab ozogamicin: a humanized anti-CD33 monoclonal antibody–drug conjugate for the treatment of newly diagnosed acute myeloid leukemia
Egan PC, Reagan JL
OncoTargets and Therapy 2018, 11:8265-8272
Published Date: 22 November 2018

Platelets enhance the ability of bone-marrow mesenchymal stem cells to promote cancer metastasis
Wang Q, Li Z, Sun L, Chen B, Zhao Y, Shen B, Zhu M, Zhao X, Xu C, Wang M, Xu W, Zhu W
OncoTargets and Therapy 2018, 11:8251-8263
Published Date: 21 November 2018

Clinical efficacy of immune checkpoint inhibitors in the treatment of unresectable advanced or recurrent gastric cancer: an evidence-based review of therapies

Togasaki K, Sukawa Y, Kanai T, Takaishi H
OncoTargets and Therapy 2018, 11:8239-8250
Published Date: 21 November 2018

Icotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression
Sun J, Jiang W, Tian D, Guo Q, Shen Z
OncoTargets and Therapy 2018, 11:8227-8237
Published Date: 21 November 2018

Cytoskeleton-associated protein 4 is a novel serodiagnostic marker for esophageal squamous-cell carcinoma
Chen L, You C, Jin X, Zhou L, Huang L, Wang Y
OncoTargets and Therapy 2018, 11:8221-8226
Published Date: 20 November 2018

Alcoholic liver disease and risk of cholangiocarcinoma: a systematic review and meta-analysis
Xiong J, Yin Z, Xu W, Shen Z, Li Y, Lu X
OncoTargets and Therapy 2018, 11:8211-8219
Published Date: 20 November 2018

Afatinib reverses ceritinib resistance (CR) in ALK/ROS1-positive non-small-cell lung cancer cell (NSCLC) via suppression of NRG1 pathway
Chen H, Zhang Q, Zhang Y, Jia B, Zhang B, Wang C
OncoTargets and Therapy 2018, 11:8201-8209
Published Date: 26 November 2018

Primary clear cell adenocarcinoma of the pancreas: a case report and literature update

Sun PJ, Yu YH, Cui XJ
OncoTargets and Therapy 2018, 11:8197-8200
Published Date: 16 November 2018

Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway
Jin YL, Xin LM, Zhou CC, Ren Y
OncoTargets and Therapy 2018, 11:8185-8195
Published Date: 16 November 2018

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion
Ye Y, Song Y, Zhuang J, Wang G, Ni J, Zhang S, Xia W
OncoTargets and Therapy 2018, 11:8175-8184
Published Date: 10 December 2018

E2F transcription factor 8 promotes cell proliferation via CCND1/p21 in esophageal squamous cell carcinoma
Chang H, Song J, Wu J, Zhang Y
OncoTargets and Therapy 2018, 11:8165-8173
Published Date: 15 November 2018

The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells
Jiang H, Fan JJ, Cheng L, Hu P, Liu RB
OncoTargets and Therapy 2018, 11:8153-8163
Published Date: 14 November 2018

Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer
Sheng ML, Dong ZH, Xie YP
OncoTargets and Therapy 2018, 11:8143-8151
Published Date: 14 November 2018

Potential role of Toll-like receptor 2 expression and polymorphisms in colon cancer susceptibility in the Saudi Arabian population
Semlali A, Parine NR, Al-Numair NS, Almutairi M, Hawsawi YM, Al Amri A, Aljebreen AM, Arafah M, Almadi MA, Azzam NA, Alharbi O, Alanazi MS
OncoTargets and Therapy 2018, 11:8127-8141
Published Date: 14 November 2018

In vitro and in vivo superior radiosensitizing effect of berbamine for head and neck squamous cell carcinoma
Zhu H, Ruan S, Jia F, Chu J, Zhu Y, Huang Y, Liu G
OncoTargets and Therapy 2018, 11:8117-8125
Published Date: 14 November 2018

Follicle-stimulating hormone inhibits cervical cancer via NF-κB pathway
Shi X, Qiu S, Zhuang W, Wang C, Zhang S, Yuan N, Yuan F, Qiao Y
OncoTargets and Therapy 2018, 11:8107-8115
Published Date: 14 November 2018

Lipocalin 2: a potential therapeutic target for breast cancer metastasis
Hu C, Yang K, Li M, Huang W, Zhang F, Wang H
OncoTargets and Therapy 2018, 11:8099-8106
Published Date: 13 November 2018

High expression of TFEB is associated with aggressive clinical features in colorectal cancer
Liang J, Jia X, Wang K, Zhao N
OncoTargets and Therapy 2018, 11:8089-8098
Published Date: 13 November 2018

Association of MLH1 single nucleotide polymorphisms with clinical outcomes of first-line irinotecan-based chemotherapy in colorectal cancer
Wang D, Zhang X, Zhang Y, Wu Y, Guan X, Zhu W, Wang M, Qi C, Shen B
OncoTargets and Therapy 2018, 11:8083-8088
Published Date: 13 November 2018

Expression of CLIC1 as a potential biomarker for oral squamous cell carcinoma: a preliminary study
Xu Y, Xu J, Feng J, Li J, Jiang C, Li X, Zou S, Wang Q, Li Y
OncoTargets and Therapy 2018, 11:8073-8081
Published Date: 12 November 2018

Celecoxib suppresses cutaneous squamous-cell carcinoma cell migration via inhibition of SDF1-induced endocytosis of CXCR4
Gong T, Yu Y, Yang B, Lin M, Huang JW, Cheng B, Ji C
OncoTargets and Therapy 2018, 11:8063-8071
Published Date: 12 November 2018

Clinicopathological and prognostic significance of circulating tumor cells in patients with esophageal cancer: a meta-analysis
Hou J, Zou K, Yang C, Leng X, Xu Y
OncoTargets and Therapy 2018, 11:8053-8061
Published Date: 12 November 2018

Potential clinical application of lncRNAs in non-small cell lung cancer
Lu T, Wang Y, Chen D, Liu J, Jiao W
OncoTargets and Therapy 2018, 11:8045-8052
Published Date: 13 November 2018

Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells
Mu M, Li Y, Zhan Y, Li X, Zhang B
OncoTargets and Therapy 2018, 11:8033-8044
Published Date: 13 November 2018

miR-517a promotes Warburg effect in HCC by directly targeting FBP1
Zhang D, Li Z, Li T, Luo D, Feng X, Liu Y, Huang J
OncoTargets and Therapy 2018, 11:8025-8032
Published Date: 13 November 2018

Patterns of regional nodal relapse after D2 lymphadenectomy in gastric cancer: rethinking the target volume

Yang W, Zhou M, Hu R, Li G, Wang Y, Shen L, Liang L, Yang J, Zhang Z
OncoTargets and Therapy 2018, 11:8015-8024
Published Date: 12 November 2018

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6 [Erratum]
Chen C, Zhang Z, Li J, Sun Y
OncoTargets and Therapy 2018, 11:8013-8014
Published Date: 12 November 2018

Long noncoding RNA H19 mediated the chemosensitivity of breast cancer cells via Wnt pathway and EMT process
Gao H, Hao G, Sun Y, Li L, Wang Y
OncoTargets and Therapy 2018, 11:8001-8012
Published Date: 9 November 2018


Lupeol inhibits growth and migration in two human colorectal cancer cell lines by suppression of Wnt–β-catenin pathway


Wang YH, Hong D, Qian YQ, Tu XZ, Wang KK, Yang XH, Shao SJ, Kong XL, Lou ZF, Jin LJ
OncoTargets and Therapy 2018, 11:7987-7999
Published Date: 9 November 2018

The prognostic roles of mRNAs of the exosomes derived from bone marrow stromal cells in common malignancies: a bioinformatic study
Zhao F, Yu YQ
OncoTargets and Therapy 2018, 11:7979-7986
Published Date: 12 November 2018

miR-185 suppresses progression of Ewing’s sarcoma via inhibiting the PI3K/AKT and Wnt/β-catenin pathways
Zhang S, Li D, Jiao G, Wang H, Yan T
OncoTargets and Therapy 2018, 11:7967-7977
Published Date: 9 November 2018

lncRNA differentiation antagonizing nonprotein coding RNA overexpression accelerates progression and indicates poor prognosis in pancreatic ductal adenocarcinoma
Chen L, Liu J, Tang T, Zhang Y, Liu M, Xu L, Zhang J
OncoTargets and Therapy 2018, 11:7955-7965
Published Date: 9 November 2018

Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell carcinoma treated with supracricoid partial laryngectomy or total laryngectomy
Xia X, Zhu YY, Diao WW, Zhu XL, Shi XH, Li WY, Gao ZQ, Li GJ, Chen XM
OncoTargets and Therapy 2018, 11:7947-7953
Published Date: 9 November 2018

TRIM37 targets AKT in the growth of lung cancer cells
Dong SM, Pang XQ, Sun HJ, Yuan CL, Mu CY, Zheng S
OncoTargets and Therapy 2018, 11:7935-7945
Published Date: 8 November 2018

MicroRNA-18a promotes hepatocellular carcinoma proliferation, migration, and invasion by targeting Bcl2L10
Wang X, Lu J, Cao J, Ma B, Gao C, Qi F
OncoTargets and Therapy 2018, 11:7919-7934
Published Date: 9 November 2018

Clinical evaluation of vascular normalization induced by recombinant human endostatin in nasopharyngeal carcinoma via dynamic contrast-enhanced ultrasonography
Yang Z, Kang M, Zhu S, Huang J, Li X, Wang R
OncoTargets and Therapy 2018, 11:7909-7917
Published Date: 8 November 2018

Therapeutic strategies of melatonin in cancer patients: a systematic review and meta-analysis
Wang Y, Wang P, Zheng X, Du X
OncoTargets and Therapy 2018, 11:7895-7908
Published Date: 8 November 2018

Transcatheter hepatic arterial infusion chemotherapy vs sorafenib in the treatment of patients with hepatocellular carcinoma of Barcelona Clinic Liver Cancer stage C: a meta-analysis of Asian population
Ni JY, Liu SS, Sun HL, Wang WD, Zhong ZL, Hou SN, Chen YT, Xu LF
OncoTargets and Therapy 2018, 11:7883-7894
Published Date: 6 November 2018

OCT4, SOX2, and NAN OG positive expression correlates with poor differentiation, advanced disease stages, and worse overall survival in HER2+ breast cancer patients
Yang F, Zhang J, Yang H
OncoTargets and Therapy 2018, 11:7873-7881
Published Date: 6 November 2018

Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro
Jiang T, Zhou ML, Fan J
OncoTargets and Therapy 2018, 11:7865-7872
Published Date: 6 November 2018

EZH2 contributes to 5-FU resistance in gastric cancer by epigenetically suppressing FBXO32 expression
Wang C, Li X, Zhang J, Ge Z, Chen H, Hu J
OncoTargets and Therapy 2018, 11:7853-7864
Published Date: 5 November 2018

TRIM32 overexpression improves chemoresistance through regulation of mitochondrial function in non-small-cell lung cancers
Du Y, Zhang W, Du B, Zang S, Wang X, Mao X, Hu Z
OncoTargets and Therapy 2018, 11:7841-7852
Published Date: 5 November 2018

Long noncoding RNA HOXD-AS1 in various cancers: a meta-analysis and TCGA data review
Zhang FH, Chen XW, Xi KH, Qiu ZQ, Wang YH, Gui Y, Hou Y, Chen KB, Zhang XB
OncoTargets and Therapy 2018, 11:7827-7840
Published Date: 5 November 2018

Intestinal metastasis from primary ROS1-positive lung adenocarcinoma cancer patients responding to crizotinib

Chen HF, Zhang QX, Zhu YC, Du KQ, Li XF, Wu LX, Wang WX, Xu CW
OncoTargets and Therapy 2018, 11:7821-7825
Published Date: 5 November 2018

Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer
Wu B, Qi R, Liu X, Qian L, Wu Z
OncoTargets and Therapy 2018, 11:7805-7820
Published Date: 5 November 2018

PTPRF as a novel tumor suppressor through deactivation of ERK1/2 signaling in gastric adenocarcinoma
Tian X, Yang C, Yang L, Sun Q, Liu N
OncoTargets and Therapy 2018, 11:7795-7803
Published Date: 2 November 2018

Huge borderline phyllodes breast tumor with repeated recurrences and progression toward more malignant phenotype: a case report and literature review
Wang Y, Zhang Y, Chen G, Liu F, Liu C, Xu T, Ma Z
OncoTargets and Therapy 2018, 11:7787-7793
Published Date: 2 November 2018

Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK
Wang J, Li J, Cao N, Li Z, Han J, Li L
OncoTargets and Therapy 2018, 11:7777-7786
Published Date: 2 November 2018

Potential targets of TMEM176A in the growth of glioblastoma cells
Liu Z, An H, Song P, Wang D, Li S, Chen K, Pang Q
OncoTargets and Therapy 2018, 11:7763-7775
Published Date: 2 November 2018

Decreased expression of peroxiredoxin1 inhibits proliferation, invasion, and metastasis of ovarian cancer cell
Zheng MJ, Wang J, Wang HM, Gao LL, Li X, Zhang WC, Gou R, Guo Q, Nie X, Liu J, Lin B
OncoTargets and Therapy 2018, 11:7745-7761
Published Date: 2 November 2018

MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells
Meng D, Lei M, Han Y, Zhao D, Zhang X, Yang Y, Liu R
OncoTargets and Therapy 2018, 11:7733-7743
Published Date: 2 November 2018

Underexpression of INPPL1 is associated with aggressive clinicopathologic characteristics in papillary thyroid carcinoma
Zhou YL, Zheng C, Chen YT, Chen XM
OncoTargets and Therapy 2018, 11:7725-7731
Published Date: 1 November 2018

lncRNA PCAT6 promotes non-small cell lung cancer cell proliferation, migration and invasion through regulating miR-330-5p
Cui LH, Xu HR, Yang W, Yu LJ
OncoTargets and Therapy 2018, 11:7715-7724
Published Date: 1 November 2018

The clinical feasibility of flexible bronchoscopy interventional therapy in patients with central airway stenosis and respiratory failure caused by malignancy
Wang J, Yang Y, Zha W, Zhang X
OncoTargets and Therapy 2018, 11:7709-7714
Published Date: 1 November 2018

Low expression level of ASK1-interacting protein-1 correlated with tumor angiogenesis and poor survival in patients with esophageal squamous cell cancer
Sun D, Chen C, Hu W, Zhong C, Fan L, Song X, Gai Z
OncoTargets and Therapy 2018, 11:7699-7707
Published Date: 1 November 2018

A meta-analysis of nivolumab for the treatment of advanced non-small-cell lung cancer
Chen S, Hu B, Li H
OncoTargets and Therapy 2018, 11:7691-7697
Published Date: 31 October 2018

16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling
Chen YC, Huang BM, Lee WC, Chen YC
OncoTargets and Therapy 2018, 11:7679-7690
Published Date: 31 October 2018

Cytotoxic effect of Drimia maritima bulb extract and induction of mitochondrial apoptotic signaling in human breast cancer cells, MCF-7 and MDA-MB-468
Hamzeloo-Moghadam M, Aghaei M, Abdolmohammadi MH, Khalaj A, Fallahian F
OncoTargets and Therapy 2018, 11:7669-7677
Published Date: 31 October 2018

A systematic review and meta-analysis of gastrointestinal events associated with nonoperative therapies for neuroendocrine tumors
Wu Q, Chen B, Yan G, Yang Z, Xiong L, He J
OncoTargets and Therapy 2018, 11:7655-7668
Published Date: 31 October 2018

Acyl-CoA dehydrogenase long chain expression is associated with esophageal squamous cell carcinoma progression and poor prognosis
Yu DL, Li HW, Wang Y, Li CQ, You D, Jiang L, Song YP, Li XH
OncoTargets and Therapy 2018, 11:7643-7653
Published Date: 31 October 2018

Clinicopathological analysis of PD-L2 expression in colorectal cancer
Guo PD, Sun ZW, Lai HJ, Yang J, Wu PP, Guo YD, Sun J
OncoTargets and Therapy 2018, 11:7635-7642
Published Date: 1 November 2018

Significance of PYK2 level as a prognosis predictor in patients with colon adenocarcinoma after surgical resection
Liu S, Chen L, Xu Y
OncoTargets and Therapy 2018, 11:7625-7634
Published Date: 31 October 2018

SIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling
Ouyang L, Yi L, Li J, Yi S, Li S, Liu P, Yang X
OncoTargets and Therapy 2018, 11:7613-7624
Published Date: 1 November 2018

Protein tyrosine phosphatase L1 inhibits high-grade serous ovarian carcinoma progression by targeting IκBα
Wang Y, Li M, Huang T, Li J
OncoTargets and Therapy 2018, 11:7603-7612
Published Date: 30 October 2018

Knockdown of immature colon carcinoma transcript-I inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest [Expression of concern]
Xie R, Zhang Y, Shen C, Cao X, Gu S, Che X
OncoTargets and Therapy 2018, 11:7601-7602
Published Date: 30 October 2018

RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma
Yu Q, Zhang N, Jiang Y, Huang Y, Lian YY, Liu T, Li N, Guan G
OncoTargets and Therapy 2018, 11:7591-7600
Published Date: 2 November 2018

GATA3 is downregulated in osteosarcoma and facilitates EMT as well as migration through regulation of slug
Ma L, Xue W, Ma X
OncoTargets and Therapy 2018, 11:7579-7589
Published Date: 30 October 2018

ADAMTS8 targets ERK to suppress cell proliferation, invasion, and metastasis of hepatocellular carcinoma
Zhao XT, Yang CR, Wu JH, Nan YM
OncoTargets and Therapy 2018, 11:7569-7578
Published Date: 29 October 2018

Sirt3 enhances glioma cell viability by stabilizing Ku70–BAX interaction
Luo K, Huang W, Tang S
OncoTargets and Therapy 2018, 11:7559-7567
Published Date: 29 October 2018

Successful alternative treatment for relapsed adult acute lymphoblastic leukemia with dendritic cells-cytokine-induced killer cells combined with a rituximab-based regimen
Xiao X, Ye X, Xu C, Huang J
OncoTargets and Therapy 2018, 11:7555-7558
Published Date: 29 October 2018

BMP-2 inhibits lung metastasis of osteosarcoma: an early investigation using an orthotopic model
Xiong Q, Wang X, Wang L, Huang Y, Tian X, Fan Y, Lin CY
OncoTargets and Therapy 2018, 11:7543-7553
Published Date: 29 October 2018

Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis
Weng YM, Peng M, Hu MX, Yao Y, Song QB
OncoTargets and Therapy 2018, 11:7529-7542
Published Date: 30 October 2018

The impact of immunosenescence on the efficacy of immune checkpoint inhibitors in melanoma patients: a meta-analysis
Li P, Yang X, Feng Y, Wu L, Ma W, Ding G, Wei Y, Sun L
OncoTargets and Therapy 2018, 11:7521-7527
Published Date: 26 October 2018

Re-biopsy status among Chinese non-small-cell lung cancer patients who progressed after icotinib therapy
Wang H, Zhang L, Si X, Zhang X, Wang M
OncoTargets and Therapy 2018, 11:7513-7519
Published Date: 26 October 2018

miR-23b-3p and miR-130a-5p affect cell growth, migration and invasion by targeting CB1R via the Wnt/β-catenin signaling pathway in gastric carcinoma
Xian X, Tang L, Wu C, Huang L
OncoTargets and Therapy 2018, 11:7503-7512
Published Date: 25 October 2018

FAM129B promoted tumor invasion and proliferation via facilitating the phosphorylation of FAK signaling and associated with adverse clinical outcome of non-small cell lung cancer patients
Zhou X, Yang F, Zhang Q, Miao Y, Hu X, Li A, Hou G, Wang Q, Kang J
OncoTargets and Therapy 2018, 11:7493-7501
Published Date: 25 October 2018

Long noncoding RNA UCA1 promotes the proliferation, invasion, and migration of nasopharyngeal carcinoma cells via modulation of miR-145
Wu J, Du M, Zhang Q, Zhang W, Fan Y, Yin L, Fei Q, Jiang X, Chen W, Zhu H, Yan P, He X, Bian X
OncoTargets and Therapy 2018, 11:7483-7492
Published Date: 25 October 2018

Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis
Li L, Cao Y, Zhou H, Li Y, He B, Zhou X, Nie Z, Liang L, Liu Y, Ye L
OncoTargets and Therapy 2018, 11:7471-7481
Published Date: 26 October 2018


The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China
Liu Y, Qian L, Yang J, Huang H, Feng J, Li X, Bian T, Ke H, Liu J, Zhang J
OncoTargets and Therapy 2018, 11:7459-7469
Published Date: 25 October 2018

ARHGAP30 suppressed lung cancer cell proliferation, migration, and invasion through inhibition of the Wnt/β-catenin signaling pathway
Mao X, Tong J
OncoTargets and Therapy 2018, 11:7447-7457
Published Date: 24 October 2018

Options of medical treatment and laryngeal function preservation in elderly patients with medial wall pyriform sinus cancer
Wang Q, Liu Y, Wu K, Zhao Y, Gao C, Tong B, Zhang M
OncoTargets and Therapy 2018, 11:7441-7446
Published Date: 1 November 2018

Regulation of cell proliferation and metastasis by microRNA-593-5p in human gastric cancer
Yu H, Wei W, Cao W, Zhan Z, Yan L, Wu K, Xie D, Cai B, Xie Y, Xiao Q
OncoTargets and Therapy 2018, 11:7429-7440
Published Date: 24 October 2018

Activated pulmonary tuberculosis in a patient with melanoma during PD-1 inhibition: a case report
He W, Zhang XM, Li WW, Kong C, Wang YY, Zhu LY, Xu RL, Deng GF, Zhang PZ
OncoTargets and Therapy 2018, 11:7423-7427
Published Date: 24 October 2018

Research progress on GP73 in malignant tumors
Liang R, Liu Z, Piao X, Zuo M, Zhang J, Liu Z, Li Y, Lin Y
OncoTargets and Therapy 2018, 11:7417-7421
Published Date: 24 October 2018

Comprehensive bioinformatics analysis identifies several potential diagnostic markers and potential roles of cyclin family members in lung adenocarcinoma
Gao LW, Wang GL
OncoTargets and Therapy 2018, 11:7407-7415
Published Date: 24 October 2018

Notch1 serves as a prognostic factor and regulates metastasis via regulating EGFR expression in hypopharyngeal squamous cell carcinoma
Tian J, Liu X, Liu X, Jing P, Sa N, Wang H, Xu W
OncoTargets and Therapy 2018, 11:7395-7405
Published Date: 24 October 2018

Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and Therapy 2018, 11:7385-7394
Published Date: 24 October 2018

The efficacy and safety of immune checkpoint inhibitor combination therapy in lung cancer: a systematic review and meta-analysis
Peng M, Li X, Lei G, Weng YM, Hu MX, Song QB
OncoTargets and Therapy 2018, 11:7369-7383
Published Date: 24 October 2018

Enzalutamide-resistant castration-resistant prostate cancer: challenges and solutions
Tucci M, Zichi C, Buttigliero C, Vignani F, Scagliotti GV, Di Maio M
OncoTargets and Therapy 2018, 11:7353-7368
Published Date: 24 October 2018

Iodine-125 seed implantation and allogenic natural killer cell immunotherapy for hepatocellular carcinoma after liver transplantation: a case report
Xie S, Wu Z, Zhou L, Liang Y, Wang X, Niu L, Xu K, Chen J, Zhang M
OncoTargets and Therapy 2018, 11:7345-7352
Published Date: 25 October 2018

Down-regulation of CXCL 11 inhibits colorectal cancer cell growth and epithelial-mesenchymal transition
Gao YJ, Liu DL, Li S, Yuan GF, Li L, Zhu HY, Cao GY
OncoTargets and Therapy 2018, 11:7333-7343
Published Date: 23 October 2018

Clinical characterization of ERBB2 exon 20 insertions and heterogeneity of outcomes responding to afatinib in Chinese lung cancer patients
Liu Z, Wu L, Cao J, Yang Z, Zhou C, Cao L, Wu H, Shen H, Jin M, Zhang Y, Mao X, Xiang J, Ma K, Li B, Zhang T, Hu Y
OncoTargets and Therapy 2018, 11:7323-7331
Published Date: 23 October 2018

Radioembolization versus chemoembolization for unresectable hepatocellular carcinoma: a meta-analysis of randomized trials
Casadei Gardini A, Tamburini E, Iñarrairaegui M, Frassineti GL, Sangro B
OncoTargets and Therapy 2018, 11:7315-7321
Published Date: 25 October 2018

MCL-1 inhibition in cancer treatment
Xiang W, Yang CY, Bai L
OncoTargets and Therapy 2018, 11:7301-7314
Published Date: 23 October 2018


Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer


Salman P, Panay S, Fernández R, Mahave M, Soza-Ried C
OncoTargets and Therapy 2018, 11:7295-7300
Published Date: 23 October 2018

Efficacy and safety analysis on dendritic cell-based vaccine-treated high-grade glioma patients: a systematic review and meta-analysis
Li C, Liu T, Zhou B, Zhou Y, Yu H, Sun Y
OncoTargets and Therapy 2018, 11:7277-7293
Published Date: 24 October 2018

Radiation therapy’s efficacy on tongue cancer: a population-based survival analysis
Zhu Y, Zhou C, He Q
OncoTargets and Therapy 2018, 11:7271-7276
Published Date: 23 October 2018

Thymosin α1 suppresses migration and invasion of PD-L1 high-expressing non-small-cell lung cancer cells via inhibition of STAT3–MMP2 signaling
Bo C, Wu Q, Zhao H, Li X, Zhou Q
OncoTargets and Therapy 2018, 11:7255-7270
Published Date: 23 October 2018

Long non-coding RNA ZEB1-AS1 promotes cell invasion and epithelial to mesenchymal transition through inducing ZEB1 expression in cervical cancer
Cheng RJ, Li N, Yang SY, Liu L, Han SY
OncoTargets and Therapy 2018, 11:7245-7253
Published Date: 18 October 2018

The elevated glutaminolysis of bladder cancer and T cells in a simulated tumor microenvironment contributes to the up-regulation of PD-L1 expression by interferon-γ
Wang LP, Yang XC, Li D, Liang ZJ, Chen YB, Ma GF, Wang YH, Li YX, Liang Y, Niu HT
OncoTargets and Therapy 2018, 11:7229-7243
Published Date: 18 October 2018

TNFα promotes glioblastoma A172 cell mitochondrial apoptosis via augmenting mitochondrial fission and repression of MAPK–ERK–YAP signaling pathways
Lu C, Chen X, Wang Q, Xu X, Xu B
OncoTargets and Therapy 2018, 11:7213-7227
Published Date: 18 October 2018

The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes
Devor EJ, Cha E, Warrier A, Miller MD, Gonzalez-Bosquet J, Leslie KK
OncoTargets and Therapy 2018, 11:7205-7211
Published Date: 18 October 2018

Knockdown of lncRNA UCA1 inhibits proliferation and invasion of papillary thyroid carcinoma through regulating miR-204/IGFBP5 axis
Liu H, Li R, Guan L, Jiang T
OncoTargets and Therapy 2018, 11:7197-7204
Published Date: 18 October 2018

Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma
Su L, Tian J, Sun J, Han N, Feng L, Yu B, Wang Y
OncoTargets and Therapy 2018, 11:7187-7196
Published Date: 18 October 2018

Dosimetric comparison of volumetric-modulated arc therapy and intensity-modulated radiation therapy in patients with cervical cancer: a meta-analysis
Bai W, Kou C, Yu W, Li Y, Hua W, Yu L, Wang J
OncoTargets and Therapy 2018, 11:7179-7186
Published Date: 18 October 2018

Prognostic value of NEK2 overexpression in digestive system cancers: a meta-analysis and systematic review
Ren Q, Li B, Liu M, Hu Z, Wang Y
OncoTargets and Therapy 2018, 11:7169-7178
Published Date: 18 October 2018

Gene expression analyses identify a relationship between stanniocalcin 2 and the malignant behavior of colorectal cancer
Wang J, Sahengbieke S, Xu X, Zhang L, Xu X, Sun L, Deng Q, Wang D, Chen D, Pan Y, Liu Z, Yu S
OncoTargets and Therapy 2018, 11:7155-7168
Published Date: 18 October 2018

Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration
Ciccarelli O, Colson A, De Saeger C, Reding R, Sempoux C, Leclercq IA, Stärkel P
OncoTargets and Therapy 2018, 11:7143-7153
Published Date: 17 October 2018

Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma
Zhang DY, Liu Z, Lu Z, Sun WL, Ma X, Zhang P, Wu BQ, Cui PY
OncoTargets and Therapy 2018, 11:7133-7142
Published Date: 17 October 2018

Overexpression of APC11 predicts worse survival in lung adenocarcinoma
Zhou J, Zhang S, Fu G, He Z, Xu Y, Ye W, Chen Z
OncoTargets and Therapy 2018, 11:7125-7132
Published Date: 17 October 2018

MicroRNA-195: a review of its role in cancers
Yu W, Liang X, Li X, Zhang Y, Sun Z, Liu Y, Wang J
OncoTargets and Therapy 2018, 11:7109-7123
Published Date: 17 October 2018

Mechanisms of resistance to BRAF and MEK inhibitors and clinical update of US Food and Drug Administration-approved targeted therapy in advanced melanoma
Kakadia S, Yarlagadda N, Awad R, Kundranda M, Niu J, Naraev B, Mina L, Dragovich T, Gimbel M, Mahmoud F
OncoTargets and Therapy 2018, 11:7095-7107
Published Date: 17 October 2018

Novel EXO-T vaccine using polyclonal CD4+ T cells armed with HER2-specific exosomes for HER2-positive breast cancer
Li R, Chibbar R, Xiang J
OncoTargets and Therapy 2018, 11:7089-7093
Published Date: 17 October 2018

A systematic review and meta-analysis on the effect of angiogenesis blockade for the treatment of gastric cancer
Bai ZG, Zhang ZT
OncoTargets and Therapy 2018, 11:7077-7087
Published Date: 17 October 2018

Platelet-to-lymphocyte ratio and lymphocyte-to-white blood cell ratio predict the efficacy of neoadjuvant chemotherapy and the prognosis of locally advanced gastric cancer patients treated with the oxaliplatin and capecitabine regimen
Tang C, Cheng X, Yu S, Wang Y, Hou J, Li Q, Shen Z, Liu T, Cui Y
OncoTargets and Therapy 2018, 11:7061-7075
Published Date: 17 October 2018

The functional verification of EGFR-CAR T-cells targeted to hypopharyngeal squamous cell carcinoma
Dong Y, Ding Y, Guo W, Huang J, Yang Z, Zhang Y, Chen X
OncoTargets and Therapy 2018, 11:7053-7059
Published Date: 16 October 2018

Clinical use of FLT3 inhibitors in acute myeloid leukemia
Sutamtewagul G, Vigil CE
OncoTargets and Therapy 2018, 11:7041-7052
Published Date: 16 October 2018

Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells
Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T
OncoTargets and Therapy 2018, 11:7031-7040
Published Date: 16 October 2018

Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway
Khophai S, Thanee M, Techasen A, Namwat N, Klanrit P, Titapun A, Jarearnrat A, Sa-Ngiamwibool P, Loilome W
OncoTargets and Therapy 2018, 11:7019-7029
Published Date: 16 October 2018

Research progress of the clinicopathologic features of lung adenosquamous carcinoma
Wang J, Wang Y, Tong M, Pan H, Li D
OncoTargets and Therapy 2018, 11:7011-7017
Published Date: 16 October 2018

TIM-3, a promising target for cancer immunotherapy
He Y, Cao J, Zhao C, Li X, Zhou C, Hirsch FR
OncoTargets and Therapy 2018, 11:7005-7009
Published Date: 16 October 2018

Decreased pretherapy serum apolipoprotein A-I is associated with extent of metastasis and poor prognosis of non-small-cell lung cancer
Shi H, Huang H, Pu J, Shi DC, Ning Y, Dong Y, Han Y, Zarogoulidis P, Bai C
OncoTargets and Therapy 2018, 11:6995-7003
Published Date: 15 October 2018

Inhibition of miR-10a-5p suppresses cholangiocarcinoma cell growth through downregulation of Akt pathway
Gao L, Yang X, Zhang H, Yu M, Long J, Yang T
OncoTargets and Therapy 2018, 11:6981-6994
Published Date: 15 October 2018

Genome-scale analysis identifies SERPINE1 and SPARC as diagnostic and prognostic biomarkers in gastric cancer
Liao P, Li W, Liu RZ, Teer JK, Xu BB, Zhang W, Li X, Mcleod HL, He YJ
OncoTargets and Therapy 2018, 11:6969-6980
Published Date: 15 October 2018

Identification of critically carcinogenesis-related genes in basal cell carcinoma
Dai J, Lin K, Huang Y, Lu Y, Chen W, Zhang X, He B, Pan Y, Wang S, Fan W
OncoTargets and Therapy 2018, 11:6957-6967
Published Date: 15 October 2018

Identification of driver genes associated with chemotherapy resistance of Ewing’s sarcoma
Liao H, Xie X, Xu Y, Huang G
OncoTargets and Therapy 2018, 11:6947-6956
Published Date: 15 October 2018

Crizotinib presented with promising efficacy but for concomitant mutation in next-generation sequencing-identified ROS1-rearranged non-small-cell lung cancer
Zeng L, Li Y, Xiao L, Xiong Y, Liu L, Jiang W, Heng J, Qu J, Yang N, Zhang Y
OncoTargets and Therapy 2018, 11:6937-6945
Published Date: 15 October 2018

SMAGP a novel biomarker of cervical cancer development and progression
Jia Y, Li H, Liu G, Song F
OncoTargets and Therapy 2018, 11:6925-6935
Published Date: 15 October 2018


NFATC2 is a novel therapeutic target for colorectal cancer stem cells


Lang T, Ding X, Kong L, Zhou X, Zhang Z, Ju HX, Ding S
OncoTargets and Therapy 2018, 11:6911-6924
Published Date: 15 October 2018

Targeting VEGF pathway to normalize the vasculature: an emerging insight in cancer therapy
Wu J, Tang Y, Liang X
OncoTargets and Therapy 2018, 11:6901-6909
Published Date: 17 October 2018

RETRACTED ARTICLE: Synergistic suppression effect on tumor growth of acute myeloid leukemia by combining cytarabine with an engineered oncolytic vaccinia virus
Peng J, Wang S, Fan W, Li S, Wu Y, Mou X, Wang J, Tong X
OncoTargets and Therapy 2018, 11:6887-6900
Published Date: 15 October 2018

Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma
Okuno K, Matsubara T, Nakamura T, Iino T, Kakimoto T, Asanuma K, Matsumine A, Sudo A
OncoTargets and Therapy 2018, 11:6879-6886
Published Date: 12 October 2018

Downregulation of miR-638 promotes progression of breast cancer and is associated with prognosis of breast cancer patients
Li M, Wang J, Liu H
OncoTargets and Therapy 2018, 11:6871-6877
Published Date: 12 October 2018

Low-dose hypomethylating agent decitabine in combination with aclacinomycin and cytarabine achieves a better outcome than standard FLAG chemotherapy in refractory/relapsed acute myeloid leukemia patients with poor-risk cytogenetics and mutations
Li L, Zhang X, Yu H, Zhang M, Xu M, Liu J, Fu Y, Meng H, Lyu C, Li X, Zhou J
OncoTargets and Therapy 2018, 11:6863-6870
Published Date: 12 October 2018

Malignant mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma harboring an EGFR mutation: a case report

Wang Y, Yang JX, Yu M, Cao DY, Shen K
OncoTargets and Therapy 2018, 11:6853-6862
Published Date: 12 October 2018

The lncRNA TUG1 promotes epithelial ovarian cancer cell proliferation and invasion via the WNT/β-catenin pathway
Liu S, Liu Y, Lu Q, Zhou X, Chen L, Liang W
OncoTargets and Therapy 2018, 11:6845-6851
Published Date: 12 October 2018

Renal Ewing sarcoma/primitive neuroectodermal tumor in a pregnant woman who underwent robot-assisted laparoscopic nephrectomy: a case report and literature review

Miao C, Yang J, Xue J, Zhu J, Chen W, Qin Y, Wang Z
OncoTargets and Therapy 2018, 11:6839-6843
Published Date: 11 October 2018

Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells
O'Day EM, Idos GE, Hill C, Chen JW, Wagner G
OncoTargets and Therapy 2018, 11:6827-6838
Published Date: 11 October 2018


SATB1 siRNA-encapsulated immunoliposomes conjugated with CD44 antibodies target and eliminate gastric cancer-initiating cells
Yang F, Zheng Z, Zheng L, Qin J, Li H, Xue X, Gao J, Fang G
OncoTargets and Therapy 2018, 11:6811-6825
Published Date: 11 October 2018

EGFR-TKI-based vs non-EGFR-TKI-based adjuvant therapy in resected non-small-cell lung cancer with EGFR mutations: a meta-analysis of randomized controlled trials
Wu JX, He Q, Ye F, Zhou QX, Chen HJ, Sun L, Wu H
OncoTargets and Therapy 2018, 11:6803-6810
Published Date: 11 October 2018

Upregulation of AKIP1 contributes to metastasis and progression and predicts poor prognosis of patients with colorectal cancer
Jiang W, Yang W, Yuan L, Liu F
OncoTargets and Therapy 2018, 11:6795-6801
Published Date: 11 October 2018

Metastatic malignancies and the effect on arterial stiffness and blood pressure levels: the possible role of chemotherapy
Res E, Kyvelou SM, Vlachopoulos C, Manousou K, Tousoulis D, Stefanadis C, Pektasides D
OncoTargets and Therapy 2018, 11:6785-6793
Published Date: 11 October 2018

MicroRNA-647 promotes the therapeutic effectiveness of argon–helium cryoablation and inhibits cell proliferation through targeting TRAF2 via the NF-κB signaling pathway in non-small cell lung cancer
Zhang YS, Chen T, Cai Y, Dong J, Bai F, Gao X, Tian L, Duan N, Liu D
OncoTargets and Therapy 2018, 11:6777-6784
Published Date: 10 October 2018

Clinical significance of serum total oxidant/antioxidant status in patients with operable and advanced gastric cancer
Du X, Zhang L, Zhang D, Yang L, Fan Y, Dong S
OncoTargets and Therapy 2018, 11:6767-6775
Published Date: 10 October 2018

Overexpression of long noncoding RNA NORAD in colorectal cancer associates with tumor progression
Wang L, Du L, Duan W, Yan S, Xie Y, Wang C
OncoTargets and Therapy 2018, 11:6757-6766
Published Date: 10 October 2018

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells
Pan B, Han H, Wu L, Xiong Y, Zhang J, Dong B, Yang Y, Chen J
OncoTargets and Therapy 2018, 11:6741-6756
Published Date: 10 October 2018

Role of monocyte-to-lymphocyte ratio in predicting sorafenib response in patients with advanced hepatocellular carcinoma
Zhu Z, Xu L, Zhuang L, Ning Z, Zhang C, Yan X, Lin J, Shen Y, Wang P, Meng Z
OncoTargets and Therapy 2018, 11:6731-6740
Published Date: 10 October 2018

Circ-DLG 1 promotes the proliferation of esophageal squamous cell carcinoma
Rong J, Wang Q, Zhang Y, Zhu D, Sun H, Tang W, Wang R, Shi W, Cao XF
OncoTargets and Therapy 2018, 11:6723-6730
Published Date: 9 October 2018

Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo
Chen M, Lu J, Wei W, Lv Y, Zhang X, Yao Y, Wang L, Ling T, Zou X
OncoTargets and Therapy 2018, 11:6705-6722
Published Date: 10 October 2018

Knockdown of RAI14 suppresses the progression of gastric cancer
Chen C, Maimaiti A, Zhang X, Qu H, Sun Q, He Q, Yu W
OncoTargets and Therapy 2018, 11:6693-6703
Published Date: 9 October 2018

Effects of thyrotropin suppression on lumber bone mineral density in postmenopausal women with differentiated thyroid carcinoma
Zhang P, Xi H, Yan R
OncoTargets and Therapy 2018, 11:6687-6692
Published Date: 9 October 2018

Clinical significance and biological roles of cyclins in gastric cancer
Zhang HP, Li SY, Wang JP, Lin J
OncoTargets and Therapy 2018, 11:6673-6685
Published Date: 9 October 2018

Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells
Jiang L, Liang QL, Liang WM, Zhang HJ, Huang J, Yuan GL, Peng XX, Cheng SA, Huang ZG, Zhang XN
OncoTargets and Therapy 2018, 11:6665-6671
Published Date: 9 October 2018

YAP regulates ALDH1A1 expression and stem cell property of bladder cancer cells
Zhao AY, Dai YJ, Lian JF, Huang Y, Lin JG, Dai YB, Xu TW
OncoTargets and Therapy 2018, 11:6657-6663
Published Date: 10 October 2018


Pim1 promotes cell proliferation and regulates glycolysis via interaction with MYC in ovarian cancer
Wu Y, Deng Y, Zhu J, Duan Y, Weng W, Wu XH
OncoTargets and Therapy 2018, 11:6647-6656
Published Date: 9 October 2018

Predictive role of skin rash in advanced pancreatic cancer patients treated with gemcitabine plus erlotinib: a systematic review and meta-analysis
Zeng M, Feng Q, Lu M, Zhou J, Yang Z, Tang J
OncoTargets and Therapy 2018, 11:6633-6646
Published Date: 8 October 2018

Male accessory breast cancer on the abdominal wall: a case report and literature review
Zhong GB, Ye XQ, Liu JL, Xiao SZ, Huang QH, Wei W
OncoTargets and Therapy 2018, 11:6625-6631
Published Date: 8 October 2018

Efficacy and safety of iodine-125 brachytherapy combined with chemotherapy in the treatment of advanced NSCLC in the elderly

Wu C, Li B, Sun G, Peng C, Xiang D
OncoTargets and Therapy 2018, 11:6617-6624
Published Date: 8 October 2018

Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro
Liu WJ, Wang H, Peng XW, Wang WD, Liu NW, Wang Y, Lu Y
OncoTargets and Therapy 2018, 11:6605-6615
Published Date: 8 October 2018

Complete response associated with lenalidomide and celecoxib in a case of primary refractory Hodgkin lymphoma

Garcia-Recio M, Martinez-Serra J, Mestre F, Bento L, Gines J, Ramos R, Daumal J, López P, Sampol A, Gutierrez A
OncoTargets and Therapy 2018, 11:6599-6603
Published Date: 8 October 2018

Nodal regulates bladder cancer cell migration and invasion via the ALK/Smad signaling pathway
Li Y, Zhong W, Zhu M, Hu S, Su X
OncoTargets and Therapy 2018, 11:6589-6597
Published Date: 5 October 2018

Knockdown of RNF6 inhibits gastric cancer cell growth by suppressing STAT3 signaling
Huang Z, Cai Y, Yang C, Chen Z, Sun H, Xu Y, Chen W, Xu D, Tian W, Wang H
OncoTargets and Therapy 2018, 11:6579-6587
Published Date: 5 October 2018

Effects of insulin-like growth factor binding protein 3 on apoptosis of cutaneous squamous cell carcinoma cells
Liu J, Guo Y, Huang Y, Xue H, Bai S, Zhu J, Xia X, Shen B, Fang W
OncoTargets and Therapy 2018, 11:6569-6577
Published Date: 5 October 2018

Radiofrequency Ablation of hepatocellular carcinoma: a meta-analysis of overall survival and recurrence-free survival
Casadei Gardini A, Marisi G, Canale M, Foschi FG, Donati G, Ercolani G, Valgiusti M, Passardi A, Frassineti GL, Scarpi E
OncoTargets and Therapy 2018, 11:6555-6567
Published Date: 5 October 2018

The efficacy and safety of apatinib for refractory malignancies: a review and meta-analysis
Sun D, Hou H, Zhang C, Zhang X
OncoTargets and Therapy 2018, 11:6539-6554
Published Date: 5 October 2018

Pembrolizumab for the treatment of patients with recurrent locally advanced or metastatic gastric or gastroesophageal junction cancer: an evidence-based review of place in therapy
Mehta R, Shah A, Almhanna K
OncoTargets and Therapy 2018, 11:6525-6537
Published Date: 4 October 2018

Immune-checkpoint inhibitors for combating T-cell dysfunction in cancer
Grywalska E, Pasiarski M, Góźdź S, Roliński J
OncoTargets and Therapy 2018, 11:6505-6524
Published Date: 4 October 2018

miR-431-5p alters the epithelial-to-mesenchymal transition markers by targeting UROC28 in hepatoma cells
Kong Q, Han J, Deng H, Wu F, Guo S, Ye Z
OncoTargets and Therapy 2018, 11:6489-6503
Published Date: 4 October 2018

The regulation of cytokine signaling by retinal determination gene network pathway in cancer
Zheng X, Liu Q, Yi M, Qin S, Wu K
OncoTargets and Therapy 2018, 11:6479-6487
Published Date: 4 October 2018


Evolving role of neurokinin 1-receptor antagonists for chemotherapy-induced nausea and vomiting
Navari RM, Schwartzberg LS
OncoTargets and Therapy 2018, 11:6459-6478
Published Date: 4 October 2018

TRIM28 is overexpressed in glioma and associated with tumor progression
Su C, Li H, Gao W
OncoTargets and Therapy 2018, 11:6447-6458
Published Date: 10 October 2018

Radix Tetrastigma hemsleyani flavone exhibits antitumor activity in colorectal cancer via Wnt/β-catenin signaling pathway
Wu X, Yu N, Zhang Y, Ye Y, Sun W, Ye L, Wu H, Yang Z, Wu L, Wang F
OncoTargets and Therapy 2018, 11:6437-6446
Published Date: 4 October 2018

Co-expression network analysis identified CDH11 in association with progression and prognosis in gastric cancer
Chen PF, Wang F, Nie JY, Feng JR, Liu J, Zhou R, Wang HL, Zhao Q
OncoTargets and Therapy 2018, 11:6425-6436
Published Date: 2 October 2018

LncRNA as a diagnostic and prognostic biomarker in bladder cancer: a systematic review and meta-analysis
Quan J, Pan X, Zhao L, Li Z, Dai K, Yan F, Liu S, Ma H, Lai Y
OncoTargets and Therapy 2018, 11:6415-6424
Published Date: 4 October 2018

Adverse events risk associated with regorafenib in the treatment of advanced solid tumors: meta-analysis of randomized controlled trials
Yin X, Yin Y, Shen C, Chen H, Wang J, Cai Z, Chen Z, Zhang B
OncoTargets and Therapy 2018, 11:6405-6414
Published Date: 2 October 2018

H19 induced by oxidative stress confers temozolomide resistance in human glioma cells via activating NF-κB signaling
Duan S, Li M, Wang Z, Wang L, Liu Y
OncoTargets and Therapy 2018, 11:6395-6404
Published Date: 2 October 2018

LINC00460 modulates KDM2A to promote cell proliferation and migration by targeting miR-342-3p in gastric cancer
Wang F, Liang S, Liu X, Han L, Wang J, Du Q
OncoTargets and Therapy 2018, 11:6383-6394
Published Date: 2 October 2018

Elemene treatment for NSCLC with multiple CNS metastases: a case report and literature review
Han YS, Zhang X, Lu Y, Dong Y, Fu H, Zhang B, Gao Y
OncoTargets and Therapy 2018, 11:6377-6382
Published Date: 2 October 2018

NOP7 interacts with β-catenin and activates β-catenin/TCF signaling in hepatocellular carcinoma cells
Wu N, Zhao J, Yuan Y, Lu C, Zhu W, Jiang Q
OncoTargets and Therapy 2018, 11:6369-6376
Published Date: 1 October 2018

Siva-1 emerges as a tissue-specific oncogene beyond its classic role of a proapoptotic gene
Vachtenheim J Jr, Lischke R, Vachtenheim J
OncoTargets and Therapy 2018, 11:6361-6367
Published Date: 1 October 2018

Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B
Cao X, He GZ
OncoTargets and Therapy 2018, 11:6351-6360
Published Date: 1 October 2018

MicroRNA-1225-5p behaves as a tumor suppressor in human glioblastoma via targeting of IRS1
Li D, Chi G, Chen Z, Jin X
OncoTargets and Therapy 2018, 11:6339-6350
Published Date: 28 September 2018

Efficacy and safety of weekly nab-paclitaxel plus cisplatin with concurrent intensity-modulated radiotherapy in patients with inoperable, locally advanced esophageal cancer: a pilot trial
Wang D, Zhang W, Qian D, Guan Y, Chen X, Zhang H, Wang J, Pang Q
OncoTargets and Therapy 2018, 11:6333-6338
Published Date: 28 September 2018

Extramedullary relapse of acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation treated by CAR T-cell therapy: a case report
Wang D, Shi R, Wang Q, Li J
OncoTargets and Therapy 2018, 11:6327-6332
Published Date: 28 September 2018

A ten-long non-coding RNA signature for predicting prognosis of patients with cervical cancer
Shen L, Yu H, Liu M, Wei D, Liu W, Li C, Chang Q
OncoTargets and Therapy 2018, 11:6317-6326
Published Date: 28 September 2018

miR-218 overexpression suppresses tumorigenesis of papillary thyroid cancer via inactivation of PTEN /PI3K/AKT pathway by targeting Runx2
Han M, Chen L, Wang Y
OncoTargets and Therapy 2018, 11:6305-6316
Published Date: 28 September 2018

LINC00152 promotes the growth and invasion of oral squamous cell carcinoma by regulating miR-139-5p
Li M, Ning J, Li Z, Wang J, Zhao C, Wang L
OncoTargets and Therapy 2018, 11:6295-6304
Published Date: 27 September 2018

Predictive value of LDH kinetics in bevacizumab treatment and survival of patients with advanced NSCLC
Li B, Li C, Guo M, Shang S, Li X, Xie P, Sun X, Yu J, Wang L
OncoTargets and Therapy 2018, 11:6287-6294
Published Date: 27 September 2018

Metabolic syndrome and the incidence of hepatocellular carcinoma: a meta-analysis of cohort studies
Chen Y, Li X, Wu S, Ye W, Lou L
OncoTargets and Therapy 2018, 11:6277-6285
Published Date: 27 September 2018

POEMS syndrome complicated with multiple ischemic vascular events: case report and review of literature
Găman M, Vlădăreanu AM, Dobrea C, Onisâi M, Marinescu C, Cîşleanu D, Ciufu C, Vasile D, Bumbea H, Voican I
OncoTargets and Therapy 2018, 11:6271-6276
Published Date: 27 September 2018

Effect of long non-coding RNA AOC4P on gastrointestinal stromal tumor cells
Hu JC, Wang Q, Jiang LX, Cai L, Zhai HY, Yao ZW, Zhang ML, Feng Y
OncoTargets and Therapy 2018, 11:6259-6269
Published Date: 26 September 2018

Overexpression of GPR35 confers drug resistance in NSCLC cells by β-arrestin/Akt signaling
Wang W, Han T, Tong W, Zhao J, Qiu X
OncoTargets and Therapy 2018, 11:6249-6257
Published Date: 26 September 2018

PLK1 as a potential prognostic marker of gastric cancer through MEK-ERK pathway on PDTX models
Dang SC, Fan YY, Cui L, Chen JX, Qu JG, Gu M
OncoTargets and Therapy 2018, 11:6239-6247
Published Date: 25 September 2018

Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities
Chaar M, Kamta J, Ait-Oudhia S
OncoTargets and Therapy 2018, 11:6227-6237
Published Date: 25 September 2018

MicroRNA-671-3p promotes the proliferation and migration of glioma cells via targeting CKAP4
Lu GF, You CY, Chen YS, Jiang H, Zheng X, Tang W, Wang X, Xu H, Geng F
OncoTargets and Therapy 2018, 11:6217-6226
Published Date: 25 September 2018

CAV2 promotes the growth of renal cell carcinoma through the EGFR/PI3K/Akt pathway
Liu F, Shangli Z, Hu Z
OncoTargets and Therapy 2018, 11:6209-6216
Published Date: 25 September 2018

SOX2, a stemness gene, induces progression of NSCLC A549 cells toward anchorage-independent growth and chemoresistance to vinblastine
Choe C, Kim H, Min S, Park S, Seo J, Roh S
OncoTargets and Therapy 2018, 11:6197-6207
Published Date: 25 September 2018

Immunotherapy combined with epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer treatment
Liang H, Liu X, Wang M
OncoTargets and Therapy 2018, 11:6189-6196
Published Date: 25 September 2018

All-trans retinoic acid-encapsulated, CD20 antibody-conjugated poly(lactic-co-glycolic acid) nanoparticles effectively target and eliminate melanoma-initiating cells in vitro
Chen X, Zhang Z, Yang S, Chen H, Wang D, Li J
OncoTargets and Therapy 2018, 11:6177-6187
Published Date: 25 September 2018

Clinical, dosimetric, and position factors for radiation-induced acute esophagitis in intensity-modulated (chemo)radiotherapy for locally advanced non-small-cell lung cancer
Huang J, He TY, Yang RH, Ji TL, Li G
OncoTargets and Therapy 2018, 11:6167-6175
Published Date: 21 September 2018

CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial–mesenchymal transition
Cao G, Chen D, Liu G, Pan Y, Liu Q
OncoTargets and Therapy 2018, 11:6153-6165
Published Date: 21 September 2018

Scalp metastases as first presentation of pulmonary adenocarcinomas: a case report

Yu Q, Subedi S, Tong Y, Wei Q, Xu H, Wang Y, Gong Y, Shi Y
OncoTargets and Therapy 2018, 11:6147-6151
Published Date: 21 September 2018

Distribution of CD4+ and CD8+ exhausted tumor-infiltrating lymphocytes in molecular subtypes of Chinese breast cancer patients
Shi F, Chang H, Zhou Q, Zhao YJ, Wu GJ, Song QK
OncoTargets and Therapy 2018, 11:6139-6145
Published Date: 21 September 2018

Is long interval from neoadjuvant chemoradiotherapy to surgery optimal for rectal cancer in the era of intensity-modulated radiotherapy?: a prospective observational study
Chang H, Jiang W, Ye WJ, Tao YL, Wang QX, Xiao WW, Gao YH
OncoTargets and Therapy 2018, 11:6129-6138
Published Date: 21 September 2018

Efficacy and safety of apatinib treatment for gastric cancer, hepatocellular carcinoma and non-small cell lung cancer: a meta-analysis
Xue J, Astère M, Zhong M, Lin H, Shen J, Zhu Y
OncoTargets and Therapy 2018, 11:6119-6128
Published Date: 21 September 2018

Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy
Li L, Zhang S, Xie D, Chen H, Zheng X, Pan D
OncoTargets and Therapy 2018, 11:6111-6118
Published Date: 20 September 2018

Lentivirus-mediated shRNA targeting MUTYH inhibits malignant phenotypes of bladder cancer SW780 cells
Gao Q, Liu Y, Xie H, Zhong Y, Liao X, Zhan H, Zhou Q, Ding M, Yang K, Li A, Liu Y, Mei HB, Cai Z
OncoTargets and Therapy 2018, 11:6101-6109
Published Date: 21 September 2018

Efficacy and safety of trastuzumab as maintenance or palliative therapy in advanced HER2-positive gastric cancer
Fu XM, Zhang Y, Yang J, Qi YL, Ming Y, Sun MM, Shang YM, Yang YH, Zhu XY, Gao QL
OncoTargets and Therapy 2018, 11:6091-6100
Published Date: 20 September 2018

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6
Chen C, Zhang Z, Li J, Sun Y
OncoTargets and Therapy 2018, 11:6081-6090
Published Date: 20 September 2018

LINK-A promotes cell proliferation through the regulation of aerobic glycolysis in non-small-cell lung cancer
Zhao W, Li W, Dai W, Huang N, Qiu J
OncoTargets and Therapy 2018, 11:6071-6080
Published Date: 20 September 2018

Comparison of short-term outcomes between minimally invasive McKeown and Ivor Lewis esophagectomy for esophageal or junctional cancer: a systematic review and meta-analysis
Deng J, Su Q, Ren Z, Wen J, Xue Z, Zhang L, Chu X
OncoTargets and Therapy 2018, 11:6057-6069
Published Date: 20 September 2018

Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature
Gallo S, Arcidiacono MV, Tisato V, Piva R, Penolazzi L, Bosi C, Feo CV, Gafà R, Secchiero P
OncoTargets and Therapy 2018, 11:6049-6056
Published Date: 20 September 2018

Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo
Wang Y, Meng Y, Zhang S, Wu H, Yang D, Nie C, Hu Q
OncoTargets and Therapy 2018, 11:6039-6048
Published Date: 20 September 2018

Oldhamianoside inhibits the growth of ovarian cancer both in vitro and in vivo via adjusting inflammation and angiogenesis signals
Li Z, Zuo Y, Hou L, Dong L, Sun X
OncoTargets and Therapy 2018, 11:6031-6037
Published Date: 19 September 2018

The predictive ability of plasma ESR 1 mutations for the efficacy of endocrine therapy in hormone-receptor-positive advanced breast cancer
Du YF, Li N, Jiao X, Li K, Yan SC
OncoTargets and Therapy 2018, 11:6023-6029
Published Date: 19 September 2018

Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesis
Zhang X, Feng H, Li Z, Li D, Liu S, Huang H, Li M
OncoTargets and Therapy 2018, 11:6001-6021
Published Date: 19 September 2018

Prognostic value of miR-17-5 p in gastrointestinal cancers: a systematic review and meta-analysis
Wang Z, Zhang J, Zhang Z, Jiang Y, Li M, Li Q, Bai L, Yao D, Wang M, Wang X
OncoTargets and Therapy 2018, 11:5991-5999
Published Date: 19 September 2018

PD1/PDL1 inhibitors for the treatment of advanced urothelial bladder cancer
Stenehjem DD, Tran D, Nkrumah MA, Gupta S
OncoTargets and Therapy 2018, 11:5973-5989
Published Date: 19 September 2018

TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression
Gao C, Qiao T, Zhang B, Yuan S, Zhuang X, Luo Y
OncoTargets and Therapy 2018, 11:5963-5971
Published Date: 18 September 2018

Treatment with olaparib monotherapy for BRCA2-mutated refractory intrahepatic cholangiocarcinoma: a case report
Cheng Y, Zhang J, Qin SK, Hua HQ
OncoTargets and Therapy 2018, 11:5957-5962
Published Date: 18 September 2018

Identification of the predictive genes for the response of colorectal cancer patients to FOLFOX therapy
Lin HJ, Qiu XK, Zhang B, Zhang JC
OncoTargets and Therapy 2018, 11:5943-5955
Published Date: 17 September 2018

Osteopontin promotes cancer cell drug resistance, invasion, and lactate production and is associated with poor outcome of patients with advanced non-small-cell lung cancer
Ouyang XP, Huang Y, Jin X, Zhao W, Hu T, Wu F, Huang J
OncoTargets and Therapy 2018, 11:5933-5941
Published Date: 19 September 2018

Successful treatment of recurrent rectal implantation metastasis of ovarian cancer by natural orifice specimen extraction surgery: a case report
Su H, Li B, Ren W, Bao M, Wang P, Liu Q, Wang X, Zhou Z, Zhou H
OncoTargets and Therapy 2018, 11:5925-5931
Published Date: 17 September 2018

Lipoprotein (a): a promising prognostic biomarker in patients with hepatocellular carcinoma after curative resection
Gao XH, Zhang SS, Chen H, Wang K, Xie W, Wang F
OncoTargets and Therapy 2018, 11:5917-5924
Published Date: 17 September 2018

Therapy-related myeloid neoplasms: clinical perspectives
Fianchi L, Criscuolo M, Fabiani E, Falconi G, Maraglino AME, Voso MT, Pagano L
OncoTargets and Therapy 2018, 11:5909-5915
Published Date: 17 September 2018

Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study
Guo J, Yang L, Cai J, Xu L, Min J, Shen Y, Xiong Z, Dong W, Bunyamanop V, Wang Z
OncoTargets and Therapy 2018, 11:5903-5908
Published Date: 18 September 2018

Elevated urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine and serum uric acid are associated with progression and are prognostic factors of colorectal cancer
Mao L, Guo C, Zheng S
OncoTargets and Therapy 2018, 11:5895-5902
Published Date: 17 September 2018

MicroRNA-140-3p enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by targeting pregnenolone X receptor
Li J, Zhao J, Wang H, Li X, Liu A, Qin Q, Li B
OncoTargets and Therapy 2018, 11:5885-5894
Published Date: 17 September 2018

A case of interstitial lung disease with alveolar hemorrhage induced by pembrolizumab
Sugano T, Seike M, Noro R, Kaburaki S, Tozuka T, Takahashi A, Takano N, Tanaka T, Kashiwada T, Takeuchi S, Minegishi Y, Saito Y, Kubota K, Terasaki Y, Gemma A
OncoTargets and Therapy 2018, 11:5879-5883
Published Date: 17 September 2018

Estrogen affects cell growth and IGF-1 receptor expression in renal cell carcinoma
Sun L, Gao Z, Luo L, Tan H, Zhang G
OncoTargets and Therapy 2018, 11:5873-5878
Published Date: 17 September 2018


Evaluation of supportive and barrier-protective skin care products in the daily prevention and treatment of cutaneous toxicity during systemic chemotherapy


Lüftner D, Dell’Acqua V, Selle F, Khalil A, Leonardi MC, De La Torre Tomás A, Shenouda G, Romero Fernandez J, Orecchia R, Moyal D, Seité S
OncoTargets and Therapy 2018, 11:5865-5872
Published Date: 17 September 2018

DACH 1 inhibits glioma invasion and tumor growth via the Wnt/catenin pathway
Wang J, Zou Y, Wu X, Chen M, Zhang S, Lu X, Wang Q
OncoTargets and Therapy 2018, 11:5853-5863
Published Date: 17 September 2018


Long-term response to first-line bevacizumab-based therapy in patients with metastatic breast cancer: results of the observational “LORENA” study
Redondo A, Ramos Vázquez M, Manso L, Gil Gil MJ, Garau Llinas I, García-Garre E, Rodríguez CA, Chacón JI, López-Vivanco G
OncoTargets and Therapy 2018, 11:5845-5852
Published Date: 17 September 2018

TMEM119 promotes gastric cancer cell migration and invasion through STAT3 signaling pathway
Zheng P, Wang W, Ji M, Zhu Q, Feng Y, Zhou F, He Q
OncoTargets and Therapy 2018, 11:5835-5844
Published Date: 13 September 2018

Combination of carcinoembryonic antigen with the American Joint Committee on Cancer TNM staging system in rectal cancer: a real-world and large population-based study
Liu Q, Lian P, Luo D, Cai S, Li Q, Li X
OncoTargets and Therapy 2018, 11:5827-5834
Published Date: 13 September 2018

Apatinib combined with docetaxel as a salvage treatment for metastatic esophageal squamous cancer: a case report

Liang LJ, Wen YX, Xia YY, Wang L, Fei JY, Jiang XD
OncoTargets and Therapy 2018, 11:5821-5826
Published Date: 13 September 2018

Subgroup analysis reveals molecular heterogeneity and provides potential precise treatment for pancreatic cancers
Zhang H, Zeng J, Tan Y, Lu L, Sun C, Liang Y, Zou H, Yang X, Tan Y
OncoTargets and Therapy 2018, 11:5811-5819
Published Date: 12 September 2018

PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation
Lv JM, Chen L, Gao Y, Huang H, Pan XW, Liu X, Chen M, Qu FJ, Li L, Wang JK, Cui XG, Xu DF
OncoTargets and Therapy 2018, 11:5797-5809
Published Date: 12 September 2018

Association of GSTP1 and P16 promoter methylation with the risk of HBV-related hepatocellular carcinoma: a meta-analysis
Li Q, Deng CL, Zhang T, Li X
OncoTargets and Therapy 2018, 11:5789-5796
Published Date: 12 September 2018

Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips
Tong Q, Wang XL, Li SB, Yang GL, Jin S, Gao ZY, Liu XB
OncoTargets and Therapy 2018, 11:5777-5787
Published Date: 12 September 2018

Ultrasound-mediated microbubble destruction: a new method in cancer immunotherapy
Tu J, Zhang H, Yu J, Liufu C, Chen Z
OncoTargets and Therapy 2018, 11:5763-5775
Published Date: 12 September 2018

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle
Gomari H, Forouzandeh Moghadam M, Soleimani M
OncoTargets and Therapy 2018, 11:5753-5762
Published Date: 12 September 2018

Long noncoding RNA SNHG6 promotes the progression of colorectal cancer through sponging miR-760 and activation of FOXC1
Zhu Y, Xing Y, Chi F, Sun W, Zhang Z, Piao D
OncoTargets and Therapy 2018, 11:5743-5752
Published Date: 12 September 2018

SOX5 induces lung adenocarcinoma angiogenesis by inducing the expression of VEGF through STAT3 signaling
Chen X, Zheng Q, Li W, Lu Y, Ni Y, Ma L, Fu Y
OncoTargets and Therapy 2018, 11:5733-5741
Published Date: 11 September 2018

IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446
Jin F, Miao Y, Xu P, Qiu X
OncoTargets and Therapy 2018, 11:5723-5731
Published Date: 11 September 2018

The incidence and risk factors of hepatotoxicity induced by perioperative hyperthermic intraperitoneal chemotherapy in gastrointestinal carcinoma patients: a retrospective study
Zheng Z, Yu H, Xiong B, Shen S, Yang H, Zhou YF
OncoTargets and Therapy 2018, 11:5715-5722
Published Date: 11 September 2018

Helicobacter pylori promotes gastric epithelial cell survival through the PLK1/PI3K/Akt pathway
Xu W, Huang Y, Yang Z, Hu Y, Shu X, Xie C, He C, Zhu Y, Lu N
OncoTargets and Therapy 2018, 11:5703-5713
Published Date: 11 September 2018

NEAT1_2—SFPQ axis mediates cisplatin resistance in liver cancer cells in vitro
Ru Y, Chen XJ, Guo WZ, Gao SG, Qi YJ, Chen P, Feng XS, Zhang SJ
OncoTargets and Therapy 2018, 11:5695-5702
Published Date: 11 September 2018

Volatile anesthetic sevoflurane suppresses lung cancer cells and miRNA interference in lung cancer cells
Wang L, Wang T, Gu JQ, Su HB
OncoTargets and Therapy 2018, 11:5689-5693
Published Date: 11 September 2018

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer
Ying Zhi L, Xu Z, Ning L, Jia Jin L, Hai Cui Y, Hong HG, Fang XJ
OncoTargets and Therapy 2018, 11:5677-5688
Published Date: 10 September 2018

The role of gene sculptor microRNAs in human precancerous lesions
Wang RH, He LY, Zhou SH
OncoTargets and Therapy 2018, 11:5667-5675
Published Date: 10 September 2018

MicroRNA-300 suppresses metastasis of oral squamous cell carcinoma by inhibiting epithelial-to-mesenchymal transition
Kang Y, Zhang Y, Sun Y, Wen Y, Sun F
OncoTargets and Therapy 2018, 11:5657-5666
Published Date: 10 September 2018

Upregulation of long noncoding RNA CCAT1-L promotes epithelial–mesenchymal transition in gastric adenocarcinoma
Fang H, Liu HM, Wu WH, Liu H, Pan Y, Li WJ
OncoTargets and Therapy 2018, 11:5647-5655
Published Date: 10 September 2018

The downregulated long noncoding RNA DHRS4-AS1 is protumoral and associated with the prognosis of clear cell renal cell carcinoma
Wang C, Wang G, Zhang Z, Wang Z, Ren M, Wang X, Li H, Yu Y, Liu J, Cai L, Li Y, Zhang D, Zhang C
OncoTargets and Therapy 2018, 11:5631-5646
Published Date: 10 September 2018

Low-frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in PTX-resistant PC-3 cells via the endoplasmic reticulum stress-mediated PI3K/Akt/mTOR signaling pathway
Wu Y, Liu X, Qin Z, Hu L, Wang X
OncoTargets and Therapy 2018, 11:5621-5630
Published Date: 10 September 2018

Podoplanin-positive cancer-associated fibroblasts predict poor prognosis in lung cancer patients
Hu G, Zhong K, Chen W, Wang S, Huang L
OncoTargets and Therapy 2018, 11:5607-5619
Published Date: 10 September 2018

Pembrolizumab and salvage chemotherapy in EGFR T790M-positive non-small-cell lung cancer with high PD-L1 expression
Tozuka T, Seike M, Minegishi Y, Kitagawa S, Kato T, Takano N, Hisakane K, Takahashi S, Kobayashi K, Kashiwada T, Sugano T, Takeuchi S, Kunugi S, Noro R, Saito Y, Kubota K, Gemma A
OncoTargets and Therapy 2018, 11:5601-5605
Published Date: 7 September 2018


Preoperative high-sensitivity C-reactive protein to lymphocyte ratio index plays a vital role in the prognosis of hepatocellular carcinoma after surgical resection


Liao M, Chen P, Liao Y, Li J, Yao W, Sun T, Liao W, Su L
OncoTargets and Therapy 2018, 11:5591-5600
Published Date: 7 September 2018

RRM1 expression and the clinicopathological characteristics of patients with non-small cell lung cancer treated with gemcitabine
Chen Y, Huang Y, Chen DM, Wu C, Leng QP, Wang WY, Deng MQ, Zhao YX, Yang XH
OncoTargets and Therapy 2018, 11:5579-5589
Published Date: 7 September 2018

Hsa_circ_0003998 promotes cell proliferation and invasion by targeting miR-326 in non-small cell lung cancer
Yu W, Jiang H, Zhang H, Li J
OncoTargets and Therapy 2018, 11:5569-5577
Published Date: 7 September 2018

CXCR2 is a novel cancer stem-like cell marker for triple-negative breast cancer
Wang Y, Tu L, Du C, Xie X, Liu Y, Wang J, Li Z, Jiang M, Cao D, Yan X, Luo F
OncoTargets and Therapy 2018, 11:5559-5567
Published Date: 6 September 2018

Negative correlation of cytoplasm TIMP3 with miR-222 indicates a good prognosis for NSCLC
Lei Y, Liu Z, Yang W
OncoTargets and Therapy 2018, 11:5551-5557
Published Date: 6 September 2018

Effective treatment of pulmonary adenocarcinoma harboring triple EGFR mutations of L858R, T790M, and cis-C797S by osimertinib, bevacizumab, and brigatinib combination therapy: a case report
Zhao J, Zou M, Lv J, Han Y, Wang G, Wang G
OncoTargets and Therapy 2018, 11:5545-5550
Published Date: 6 September 2018

Nomograms for predicting long-term overall survival and disease-specific survival of patients with clear cell renal cell carcinoma
Zhang GH, Wu Y, Zhang JS, Fang ZQ, Liu ZX, Xu ZH, Fan YD
OncoTargets and Therapy 2018, 11:5535-5544
Published Date: 6 September 2018

Feasibility of radical hysterectomy in women with FIGO stage IIB cervical cancer: an observation study of 10-year experience in a tertiary center
Yuan L, Guo JQ, Zhang XC, Chen M, Xu CJ, Yao LQ
OncoTargets and Therapy 2018, 11:5527-5533
Published Date: 19 September 2018

Prognostic significance of NANOG expression in solid tumors: a meta-analysis
Zhao LQ, Liu J, Chen S, Fang C, Zhang XQ, Luo ZB
OncoTargets and Therapy 2018, 11:5515-5526
Published Date: 6 September 2018

An evaluation of the clinical diagnostic value of contrast-enhanced ultrasound combined with contrast-enhanced computed tomography in space-occupying lesions of the kidney [Corrigendum]
Lu J, Jiao D, Cong Z, Tian W
OncoTargets and Therapy 2018, 11:5513-5514
Published Date: 5 September 2018

Comparison of efficacy and toxicity between nedaplatin and cisplatin in treating malignant pleural effusion
Zhong LZ, Xu HY, Zhao ZM, Zhang GM, Lin FW
OncoTargets and Therapy 2018, 11:5509-5512
Published Date: 5 September 2018

Suppression of c-MET overcomes erlotinib resistance in tongue cancer cells
Huang K, Liu D
OncoTargets and Therapy 2018, 11:5499-5508
Published Date: 5 September 2018

Absence of AIF1L contributes to cell migration and a poor prognosis of breast cancer
Liu P, Li W, Hu Y, Jiang Y
OncoTargets and Therapy 2018, 11:5485-5498
Published Date: 5 September 2018

Altered fractionation radiotherapy with or without chemotherapy in the treatment of head and neck cancer: a network meta-analysis
Liu Y, Kou C, Bai W, Liu X, Song Y, Zhang L, Wang M, Zhang Y, You Y, Yin Y, Jiang X, Xin Y
OncoTargets and Therapy 2018, 11:5465-5483
Published Date: 4 September 2018

Clinical benefit of fulvestrant monotherapy in the multimodal treatment of hormone receptor and HER2 positive advanced breast cancer: a case series
Rusz O, Kószó R, Dobi Á, Csenki M, Valicsek E, Nikolényi A, Uhercsák G, Cserháti A, Kahán Z
OncoTargets and Therapy 2018, 11:5459-5463
Published Date: 4 September 2018

Prognostic value of CD44v6 expression in breast cancer: a meta-analysis
Qiao GL, Song LN, Deng ZF, Chen Y, Ma LJ
OncoTargets and Therapy 2018, 11:5451-5457
Published Date: 4 September 2018

Mifepristone inhibits proliferation, migration and invasion of HUUA cells and promotes its apoptosis by regulation of FAK and PI3K/AKT signaling pathway
Sang L, Lu D, Zhang J, Du S, Zhao X
OncoTargets and Therapy 2018, 11:5441-5449
Published Date: 4 September 2018

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage
Liu WJ, Yin YB, Sun JY, Feng S, Ma JK, Fu XY, Hou YJ, Yang MF, Sun BL, Fan CD
OncoTargets and Therapy 2018, 11:5429-5439
Published Date: 4 September 2018

MicroRNA 628 suppresses migration and invasion of breast cancer stem cells through targeting SOS1
Lin C, Gao B, Yan X, Lei Z, Chen K, Li Y, Zeng Q, Chen Z, Li H
OncoTargets and Therapy 2018, 11:5419-5428
Published Date: 4 September 2018

Postoperative adjuvant chemo (embolization) therapy for hepatocellular carcinoma with portal vein tumor thrombosis
Zhang YF, Shang H, Zeng XL, Ji H, Li YM, Lu HW
OncoTargets and Therapy 2018, 11:5407-5417
Published Date: 3 September 2018

RGD-modified nanoliposomes containing quercetin for lung cancer targeted treatment
Zhou X, Liu H, Zhao H, Wang T
OncoTargets and Therapy 2018, 11:5397-5405
Published Date: 3 September 2018

Successful cisplatin-etoposide chemotherapy-based treatment of a primary small cell neuroendocrine carcinoma of the tonsil with multiple metastases: a case report

Wang X, Chen Q, Meng J
OncoTargets and Therapy 2018, 11:5391-5395
Published Date: 3 September 2018

Expression profiles of long noncoding RNAs in lung adenocarcinoma
Zhao B, Xu H, Ai X, Adalat Y, Tong Y, Zhang J, Yang S
OncoTargets and Therapy 2018, 11:5383-5390
Published Date: 6 September 2018

STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells
Gao F, Yu XL, Meng RQ, Wang JS, Jia L
OncoTargets and Therapy 2018, 11:5371-5381
Published Date: 31 August 2018

SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer
Yi N, Xiao M, Jiang F, Liu Z, Ni W, Lu C, Ni R, Chen W
OncoTargets and Therapy 2018, 11:5359-5370
Published Date: 3 September 2018

Genome-wide profiling reveals cancer-related genes with switched alternative polyadenylation sites in colorectal cancer
Yang X, Wu J, Xu W, Tan S, Chen C, Wang X, Sun J, Kang Y
OncoTargets and Therapy 2018, 11:5349-5357
Published Date: 31 August 2018

Lymphangioleiomyomatosis: a case report and review of diagnosis and treatment

Liu Y, Guo Z, Zhao C, Li X, Liu H, Chen J
OncoTargets and Therapy 2018, 11:5339-5347
Published Date: 31 August 2018


Apatinib mesylate tablet in the treatment of advanced malignant melanoma

Yang L, Zhu H, Luo P, Chen S, Xu Y, Wang C
OncoTargets and Therapy 2018, 11:5333-5338
Published Date: 31 August 2018

Prognostic role of long non-coding RNA HNF1A-AS1 in Chinese cancer patients: a meta-analysis
Zhuang C, Zheng L, Wang P
OncoTargets and Therapy 2018, 11:5325-5332
Published Date: 31 August 2018

Eukaryotic translation initiation factor 3 subunit G (EI F3G) resensitized HC T116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1
Yang C, Liu X, Li C, Li S, Du W, Yang D
OncoTargets and Therapy 2018, 11:5315-5324
Published Date: 31 August 2018


E2F3 promotes cancer growth and is overexpressed through copy number variation in human melanoma


Feng Z, Peng C, Li D, Zhang D, Li X, Cui F, Chen Y, He Q
OncoTargets and Therapy 2018, 11:5303-5313
Published Date: 30 August 2018

miR-376a inhibits breast cancer cell progression by targeting neuropilin-1 NR
Zhang L, Chen Y, Wang H, Zheng X, Li C, Han Z
OncoTargets and Therapy 2018, 11:5293-5302
Published Date: 30 August 2018

Successful treatment of relapsed testicular embryonal rhabdomyosarcoma with Endostar and traditional chemotherapy: a case report
Han T, Chen JJ, Luan YT, Chen XX, Yang XD, Zhang Y, Li G, Wang D, Zheng ZD
OncoTargets and Therapy 2018, 11:5287-5291
Published Date: 30 August 2018

Microsurgical treatment of parafalcine meningiomas: a retrospective study of 126 cases
Kong X, Gong S, Lee IT, Yang Y
OncoTargets and Therapy 2018, 11:5279-5285
Published Date: 30 August 2018

Long noncoding RNA Sox2 overlapping transcript (SOX2OT) promotes non-small-cell lung cancer migration and invasion via sponging microRNA 132 (miR-132)
Zhang K, Li Y, Qu L, Ma X, Zhao H, Tang Y
OncoTargets and Therapy 2018, 11:5269-5278
Published Date: 30 August 2018

Prognostic role of aspartate aminotransferase-lymphocyte ratio index in patients with metastatic colorectal cancer: results from the randomized ITACa trial
Casadei Gardini A, Scarpi E, Orlandi E, Tassinari D, Leo S, Bernardini I, Gelsomino F, Tamberi S, Ruscelli S, Vespignani R, Ronconi S, Frassineti GL, Amadori D, Passardi A
OncoTargets and Therapy 2018, 11:5261-5268
Published Date: 29 August 2018

Profile of abemaciclib and its potential in the treatment of breast cancer
Martin JM, Goldstein LJ
OncoTargets and Therapy 2018, 11:5253-5259
Published Date: 29 August 2018

miR-361-5p inhibits glioma migration and invasion by targeting SND1
Liu J, Yang J, Yu L, Rao C, Wang Q, Sun CY, Shi CJ, Hua D, Zhou XX, Luo WJ, Wang R, Li WP, Yu SZ
OncoTargets and Therapy 2018, 11:5239-5252
Published Date: 28 August 2018

Surgical therapy and next-generation sequencing-based genetic alteration analysis of malignant solitary fibrous tumor of the pleura
Song Z, Yang F, Zhang Y, Fan P, Liu G, Li C, Ding W, Zhang Y, Xu X, Ye Y
OncoTargets and Therapy 2018, 11:5227-5238
Published Date: 28 August 2018

Magnolol exerts anticancer activity in hepatocellular carcinoma cells through regulating endoplasmic reticulum stress-mediated apoptotic signaling
Wang YD, Sun XJ, Yang WJ, Li J, Yin JJ
OncoTargets and Therapy 2018, 11:5219-5226
Published Date: 28 August 2018

Overexpression of long noncoding RNA LINC00882 is associated with poor prognosis in hepatocellular carcinoma
Zhu L, Huang F, Wan T, Xu H, Zhao Q
OncoTargets and Therapy 2018, 11:5209-5217
Published Date: 13 September 2018

Radiotherapy for one rectal cancer patient with cirrhosis and moderate to severe thrombocytopenia: a case report

Shi X, Xia H, Zhang W, Li G, Li A
OncoTargets and Therapy 2018, 11:5203-5207
Published Date: 27 August 2018

Alternative treatment strategies to sorafenib in patients with advanced hepatocellular carcinoma: a meta-analysis of randomized Phase III trials
Wang H, Wang HF, Yu ZC, Liu HH
OncoTargets and Therapy 2018, 11:5195-5201
Published Date: 27 August 2018

125I seed brachytherapy versus external beam radiation therapy for the palliation of painful bone metastases of lung cancer after one cycle of chemotherapy progression
Xiang Z, Wang L, Yan H, Zhong Z, Liu W, Mo Z, Gao F, Zhang F
OncoTargets and Therapy 2018, 11:5183-5193
Published Date: 27 August 2018

Prognostic value of SOX2, CyclinD1, P53, and ki-67 in patients with esophageal squamous cell carcinoma

Wang H, Zhou Y, Liu Q, Xu J, Ma Y
OncoTargets and Therapy 2018, 11:5171-5181
Published Date: 24 August 2018

Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia
Ding L, Zhang W, Yang L, Pelicano H, Zhou K, Yin R, Huang R, Zeng J
OncoTargets and Therapy 2018, 11:5151-5170
Published Date: 24 August 2018

Peripheral blood lymphocyte responses to cytomegalovirus seropositivity after allogeneic-hematopoietic stem cell transplantation
Zhang J, Chen X, Rong G, Xu T, Zhao H, Chen D, Wu L, Huang P, Wang F
OncoTargets and Therapy 2018, 11:5143-5150
Published Date: 24 August 2018

Antitumor effects of nadroparin combined with radiotherapy in Lewis lung cancer models
Zhuang X, Qiao T, Yuan S, Zhang Q, Chen W, Luo Y, Xu G
OncoTargets and Therapy 2018, 11:5133-5142
Published Date: 24 August 2018

Synergistic antitumoral efficacy of a novel replicative adenovirus SG611-PDCD5 and daunorubicin in human leukemic cells
Zhou YL, Yao QM, Zhou J, Chang Y, Li JL, Wang YZ, Wu HP, Chen YH, Liu YR, Huang XJ, Ruan GR
OncoTargets and Therapy 2018, 11:5121-5132
Published Date: 23 August 2018

MiRNA-16 inhibited oral squamous carcinoma tumor growth in vitro and in vivo via suppressing Wnt/β-catenin signaling pathway
Liu L, Jiang H, Zhao J, Wen H
OncoTargets and Therapy 2018, 11:5111-5119
Published Date: 23 August 2018

Effect of lncRNA ANRIL silencing on anoikis and cell cycle in human glioma via microRNA-203a
Dai W, Tian C, Jin S
OncoTargets and Therapy 2018, 11:5103-5109
Published Date: 23 August 2018

Spotlight on lorlatinib and its potential in the treatment of NSCLC: the evidence to date
Akamine T, Toyokawa G, Tagawa T, Seto T
OncoTargets and Therapy 2018, 11:5093-5101
Published Date: 22 August 2018

Prognostic and clinicopathological significance of DEPTOR expression in cancer patients: a meta-analysis
Hu B, Shi D, Lv X, Wu F, Chen S, Shao Z
OncoTargets and Therapy 2018, 11:5083-5092
Published Date: 22 August 2018

miRNA-543 promotes cell migration and invasion by targeting SPOP in gastric cancer
Xu J, Wang F, Wang X, He Z, Zhu X
OncoTargets and Therapy 2018, 11:5075-5082
Published Date: 21 August 2018

Risk of bleeding associated with antiangiogenic monoclonal antibodies bevacizumab and ramucirumab: a meta-analysis of 85 randomized controlled trials
Xiao B, Wang W, Zhang D
OncoTargets and Therapy 2018, 11:5059-5074
Published Date: 21 August 2018

Analysis of the clinical significance of DCLK1+ colorectal cancer using novel monoclonal antibodies against DCLK1
Dai T, Hu Y, Lv F, Ozawa T, Sun X, Huang J, Han X, Kishi H, Muraguchi A, Jin A
OncoTargets and Therapy 2018, 11:5047-5057
Published Date: 21 August 2018

Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling [Retraction]
Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y, Kan Q
OncoTargets and Therapy 2018, 11:5045-5046
Published Date: 21 August 2018

Long noncoding RNA XIST promotes proliferation and invasion by targeting miR-141 in papillary thyroid carcinoma
Xu Y, Wang J, Wang J
OncoTargets and Therapy 2018, 11:5035-5043
Published Date: 21 August 2018

Minichromosome maintenance protein 2 correlates with the malignant status and regulates proliferation and cell cycle in lung squamous cell carcinoma
Wu W, Wang X, Shan C, Li Y, Li F
OncoTargets and Therapy 2018, 11:5025-5034
Published Date: 20 August 2018

Molecular mechanism of activated T cells in breast cancer
Wu J, Li M, Zhang Y, Cai Y, Zhao G
OncoTargets and Therapy 2018, 11:5015-5024
Published Date: 20 August 2018

Cauda equine syndrome as the primary symptom of leptomeningeal metastases from lung cancer: a case report and review of literature

Liu Y, Wang B, Qian Y, Di D, Wang M, Zhang X
OncoTargets and Therapy 2018, 11:5009-5013
Published Date: 20 August 2018

Long non-coding RNA MEG3 suppresses survival, migration, and invasion of cervical cancer
Chen X, Qu J
OncoTargets and Therapy 2018, 11:4999-5007
Published Date: 20 August 2018

ALK-rearrangement neuroendocrine carcinoma of the lung: a comprehensive study of a rare case series and review of literature

Zheng Q, Zheng M, Jin Y, Shen X, Shan L, Shen L, Sun Y, Chen H, Li Y
OncoTargets and Therapy 2018, 11:4991-4998
Published Date: 17 August 2018

High CEP55 expression is associated with poor prognosis in non-small-cell lung cancer
Jiang C, Zhang Y, Li Y, Lu J, Huang Q, Xu R, Feng Y, Yan S
OncoTargets and Therapy 2018, 11:4979-4990
Published Date: 17 August 2018

Long non-coding RNA NAP1L6 promotes tumor progression and predicts poor prognosis in prostate cancer by targeting Inhibin-β A
Zheng Y, Gao Y, Li X, Si S, Xu H, Qi F, Wang J, Cheng G, Hua L, Yang H
OncoTargets and Therapy 2018, 11:4965-4977
Published Date: 17 August 2018

Reduced expression of Nrdp1 predicts a poor prognosis in human hepatocellular carcinoma
Shao X, Lu Q, Wang G, Huang W, Yang L, Chen Z
OncoTargets and Therapy 2018, 11:4955-4963
Published Date: 17 August 2018

Injection of an SV40 transcriptional terminator causes embryonic lethality: a possible zebrafish model for screening nonhomologous end-joining inhibitors
Yang Z, Chen S, Xue S, Li X, Hu J, Sun Z, Cui H
OncoTargets and Therapy 2018, 11:4945-4953
Published Date: 17 August 2018

The effects of beta-blocker use on cancer prognosis: a meta-analysis based on 319,006 patients
Na Z, Qiao X, Hao X, Fan L, Xiao Y, Shao Y, Sun M, Feng Z, Guo W, Li J, Li J, Li D
OncoTargets and Therapy 2018, 11:4913-4944
Published Date: 20 August 2018

MicroRNA-21-5p promotes proliferation of gastric cancer cells through targeting SMAD7
Jiang Y, Zhang M, Guo T, Yang C, Zhang C, Hao J
OncoTargets and Therapy 2018, 11:4901-4911
Published Date: 15 August 2018

Downregulation of lncRNA ANRIL suppresses growth and metastasis in human osteosarcoma cells
Guan H, Mei Y, Mi Y, Li C, Sun X, Zhao X, Liu J, Cao W, Li Y, Wang Y
OncoTargets and Therapy 2018, 11:4893-4899
Published Date: 14 August 2018

Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis
Gao S, Zhao ZY, Wu R, Zhang Y, Zhang ZY
OncoTargets and Therapy 2018, 11:4877-4891
Published Date: 14 August 2018

PRMT7 contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with HSPA5 and EEF2
Cheng D, He Z, Zheng L, Xie D, Dong S, Zhang P
OncoTargets and Therapy 2018, 11:4869-4876
Published Date: 14 August 2018

Prognostic value of nutritional markers in nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy: a propensity score matching study
Oei RW, Ye L, Huang J, Kong F, Xu T, Shen C, Wang X, He X, Kong L, Hu C, Ying H
OncoTargets and Therapy 2018, 11:4857-4868
Published Date: 14 August 2018

Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics
Ge H, Yan Y, Wu D, Huang Y, Tian F
OncoTargets and Therapy 2018, 11:4845-4855
Published Date: 14 August 2018

MicroRNA-194 regulates cell viability and apoptosis by targeting CDH2 in prostatic cancer
Gao S, Zhao Z, Wu R, Wu L, Tian X, Zhang Z
OncoTargets and Therapy 2018, 11:4837-4844
Published Date: 14 August 2018

Adenosquamous carcinoma of the lung
Li C, Lu H
OncoTargets and Therapy 2018, 11:4829-4835
Published Date: 14 August 2018

Spotlight on copanlisib and its potential in the treatment of relapsed/refractory follicular lymphoma: evidence to date
Mensah FA, Blaize JP, Bryan LJ
OncoTargets and Therapy 2018, 11:4817-4827
Published Date: 13 August 2018

Mesenteric fibromatosis misdiagnosed with lymph node metastasis after successful laparoscopic right hemicolectomy: a report of two cases with review of literature

Wang P, Zhou H, Zhou Z, Liang J
OncoTargets and Therapy 2018, 11:4811-4816
Published Date: 13 August 2018

Intestinal microbiota: a novel perspective in colorectal cancer biotherapeutics
Ding C, Tang W, Fan X, Wu G
OncoTargets and Therapy 2018, 11:4797-4810
Published Date: 13 August 2018

Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro
Tian Y, Liu Z, Zhang L, Zhang J, Han X, Wang Q, Cheng W
OncoTargets and Therapy 2018, 11:4785-4795
Published Date: 10 August 2018

sLAG-3 in non-small-cell lung cancer patients’ serum
He Y, Wang Y, Zhao S, Zhao C, Zhou C, Hirsch FR
OncoTargets and Therapy 2018, 11:4781-4784
Published Date: 13 August 2018

MSX1 induces G0/G1 arrest and apoptosis by suppressing Notch signaling and is frequently methylated in cervical cancer
Yue Y, Zhou K, Li J, Jiang S, Li C, Men H
OncoTargets and Therapy 2018, 11:4769-4780
Published Date: 10 August 2018

An integrated bioinformatical analysis to evaluate the role of KIF4A as a prognostic biomarker for breast cancer
Xue D, Cheng P, Han M, Liu X, Xue L, Ye C, Wang K, Huang J
OncoTargets and Therapy 2018, 11:4755-4768
Published Date: 10 August 2018

Effect of KI-67 positive cellular index on prognosis after hepatectomy in Barcelona Clinic Liver Cancer stage A and B hepatocellular carcinoma with microvascular invasion
Li HH, Qi LN, Ma L, Chen ZS, Xiang BD, Li LQ
OncoTargets and Therapy 2018, 11:4747-4754
Published Date: 10 August 2018

The effectiveness of afatinib and osimertinib in a Chinese patient with advanced lung adenocarcinoma harboring a rare triple EGFR mutation (R670W/H835L/L833V): a case report and literature review

Qin BD, Jiao XD, Yuan LY, Liu K, Wang Z, Qin WX, Zang YS
OncoTargets and Therapy 2018, 11:4739-4745
Published Date: 10 August 2018

Non-small cell lung cancer leptomeningeal metastases treated with intrathecal therapy plus osimertinib and temozolomide and whole-brain radiation therapy: a case report
Wang Y, Liu S, Wei X, Yan B, Li J, Su Z, Liu A, Zhang Y
OncoTargets and Therapy 2018, 11:4733-4738
Published Date: 10 August 2018

Enhanced anticancer effects of low-dose curcumin with non-invasive pulsed electric field on PANC-1 cells
Lu CH, Lin SH, Hsieh CH, Chen WT, Chao CY
OncoTargets and Therapy 2018, 11:4723-4732
Published Date: 10 August 2018

RETRACTED ARTICLE: miR-497 inhibited proliferation, migration and invasion of thyroid papillary carcinoma cells by negatively regulating YAP1 expression
Cheng H, Dong H, Feng J, Tian H, Zhang H, Xu L
OncoTargets and Therapy 2018, 11:4711-4721
Published Date: 10 August 2018

Characterization of microRNA expression in primary human colon adenocarcinoma cells (SW480) and their lymph node metastatic derivatives (SW620)
Yan W, Yang W, Liu Z, Wu G
OncoTargets and Therapy 2018, 11:4701-4709
Published Date: 10 August 2018

B7-H3 promotes metastasis, proliferation, and epithelial-mesenchymal transition in lung adenocarcinoma
Yu TT, Zhang T, Lu X, Wang RZ
OncoTargets and Therapy 2018, 11:4693-4700
Published Date: 10 August 2018

Stereotactic body radiotherapy using the CyberKnife® system in the treatment of patients with liver metastases: state of the art

Ihnát P, Skácelíková E, Tesař M, Penka I
OncoTargets and Therapy 2018, 11:4685-4691
Published Date: 10 August 2018

Drug response to PD-1/PD-L1 blockade: based on biomarkers
Chen Q, Li T, Yue W
OncoTargets and Therapy 2018, 11:4673-4683
Published Date: 8 August 2018

Eyes absent homologue 2 predicts a favorable prognosis in colorectal cancer
Zheng J, Cao F, Huang X, Ramen K, Xu X, Zhu Y, Chang W, Shan Y, Guo A
OncoTargets and Therapy 2018, 11:4661-4671
Published Date: 8 August 2018

Relationship of PPARG, PPARGC1A, and PPARGC1B polymorphisms with susceptibility to hepatocellular carcinoma in an eastern Chinese Han population
Zhang S, Jiang J, Chen Z, Wang Y, Tang W, Chen Y, Liu L
OncoTargets and Therapy 2018, 11:4651-4660
Published Date: 8 August 2018

The efficacy and safety of intravesical gemcitabine vs Bacille Calmette-Guérin for adjuvant treatment of non-muscle invasive bladder cancer: a meta-analysis
Ye Z, Chen J, Hong Y, Xin W, Yang S, Rao Y
OncoTargets and Therapy 2018, 11:4641-4649
Published Date: 8 August 2018

A long noncoding RNA MAP3K1-2 promotes proliferation and invasion in gastric cancer
Wu L, Yin JH, Guan YY, Liu HL, Shen HL, Wang XJ, Han BH, Zhou MW, Gu XD
OncoTargets and Therapy 2018, 11:4631-4639
Published Date: 7 August 2018

Effective nivolumab sequential thoracic radiotherapy in elderly patients with advanced squamous cell lung cancer: did radiation therapy play a role? A case report

Lazzari G, Terlizzi A, Porrazzo G, Devicienti S, Perri F, Della Vittoria Scarpati G, Silvano G
OncoTargets and Therapy 2018, 11:4621-4629
Published Date: 7 August 2018

CTLA4 tagging polymorphisms and risk of colorectal cancer: a case–control study involving 2,306 subjects
Zou C, Qiu H, Tang W, Wang Y, Lan B, Chen Y
OncoTargets and Therapy 2018, 11:4609-4619
Published Date: 7 August 2018

Current status and dilemma of second-line treatment in advanced pancreatic cancer: is there a silver lining?
Hua J, Shi S, Liang D, Liang C, Meng Q, Zhang B, Ni Q, Xu J, Yu X
OncoTargets and Therapy 2018, 11:4591-4608
Published Date: 6 August 2018

Brentuximab vedotin in Hodgkin lymphoma and anaplastic large-cell lymphoma: an evidence-based review
Donato EM, Fernández-Zarzoso M, Hueso JA, de la Rubia J
OncoTargets and Therapy 2018, 11:4583-4590
Published Date: 6 August 2018

Change in non-small-cell lung cancer tumor size in patients treated with nintedanib plus docetaxel: analyses from the Phase III LUME-Lung 1 study
Reck M, Mellemgaard A, Novello S, Postmus PE, Gaschler-Markefski B, Kaiser R, Buchner H
OncoTargets and Therapy 2018, 11:4573-4582
Published Date: 6 August 2018

Phytochemical analysis and antioxidant and anticancer activities of mastic gum resin from Pistacia atlantica subspecies kurdica

Rahman HS
OncoTargets and Therapy 2018, 11:4559-4572
Published Date: 6 August 2018

Prognostic value of selected preoperative inflammation-based scores in patients with high-risk localized prostate cancer who underwent radical prostatectomy
Shu K, Zheng Y, Chen J, Li W, Jiang K
OncoTargets and Therapy 2018, 11:4551-4558
Published Date: 3 August 2018

Case report of a primary prostatic urothelial carcinoma patient with sustained fever

Zhang S, Guo Z
OncoTargets and Therapy 2018, 11:4547-4550
Published Date: 3 August 2018

Hypoxia-regulated lncRNA CRPAT4 promotes cell migration via regulating AVL9 in clear cell renal cell carcinomas
Zhang W, Wang J, Chai R, Zhong G, Zhang C, Cao W, Yan L, Zhang X, Xu Z
OncoTargets and Therapy 2018, 11:4537-4545
Published Date: 3 August 2018

Relationship between HER2 gene status and selected potential biological features related to trastuzumab resistance and its influence on survival of breast cancer patients undergoing trastuzumab adjuvant treatment
Adamczyk A, Kruczak A, Harazin-Lechowska A, Ambicka A, Grela-Wojewoda A, Domagała-Haduch M, Janecka-Widła A, Majchrzyk K, Cichocka A, Ryś J, Niemiec J
OncoTargets and Therapy 2018, 11:4525-4535
Published Date: 3 August 2018

Melittin induces NSCLC apoptosis via inhibition of miR-183
Gao D, Zhang J, Bai L, Li F, Dong Y, Li Q
OncoTargets and Therapy 2018, 11:4511-4523
Published Date: 1 August 2018

HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma
Wu CZ, Zheng JJ, Bai YH, Xia P, Zhang HC, Guo Y
OncoTargets and Therapy 2018, 11:4501-4510
Published Date: 1 August 2018

Cancer/testis antigens (CTAs) expression in resected lung cancer
Jin S, Cao S, Li J, Meng Q, Wang C, Yao L, Lang Y, Cao J, Shen J, Pan B, Hu J, Yu Y
OncoTargets and Therapy 2018, 11:4491-4499
Published Date: 1 August 2018

Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo
Zhang Y, Zhang XX, Yuan RY, Ren T, Shao ZY, Wang HF, Cai WL, Chen LT, Wang XA, Wang P
OncoTargets and Therapy 2018, 11:4479-4490
Published Date: 1 August 2018

miR-141-3p is a key negative regulator of the EGFR pathway in osteosarcoma
Wang J, Wang G, Li B, Qiu C, He M
OncoTargets and Therapy 2018, 11:4461-4478
Published Date: 31 July 2018

Metformin induces miR-378 to downregulate the CDK1, leading to suppression of cell proliferation in hepatocellular carcinoma
Zhou J, Han S, Qian W, Gu Y, Li X, Yang K
OncoTargets and Therapy 2018, 11:4451-4459
Published Date: 31 July 2018

Effect of first-line endocrine therapy in patients with hormone-sensitive advanced breast cancer: a network meta-analysis [Corrigendum]
Zhang T, Feng F, Zhao W, Tian J, Yao Y, Zhou C, Dong S, Wang C, Zang C, Lv Q, Sun C
OncoTargets and Therapy 2018, 11:4449-4450
Published Date: 31 July 2018

Outcome of eribulin as a late treatment line for Thai metastatic breast cancer patients
Ditsatham C, Chitapanarux I, Somwangprasert A, Watcharachan K, Wongmaneerung P, Charoentum C, Chewaskulyong B, Chakrabandhu S, Onchan W, Teeyasuntranonn A, Sripan P
OncoTargets and Therapy 2018, 11:4443-4447
Published Date: 31 July 2018

LINC00888 promoted tumorigenicity of melanoma via miR-126/CRK signaling axis
Lu W, Tao X, Fan Y, Tang Y, Xu X, Fan S, Huang Y, Yu Y, Luo D
OncoTargets and Therapy 2018, 11:4431-4442
Published Date: 31 July 2018


Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NFκB signaling pathway


Xue Y, Yang L, Li J, Yan Y, Jiang Q, Shen L, Yang S, Shen B, Huang R, Yan J, Guo H
OncoTargets and Therapy 2018, 11:4413-4429
Published Date: 30 July 2018


Reversible posterior leukoencephalopathy syndrome induced by apatinib: a case report and literature review


Li XT, Chai J, Wang Z, Lu L, Zhao QY, Zhou J, Ju F
OncoTargets and Therapy 2018, 11:4407-4411
Published Date: 30 July 2018

Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest
Li XQ, Bai YL, Zhang DL, Jiao HS, He RX
OncoTargets and Therapy 2018, 11:4395-4405
Published Date: 27 July 2018

HOXA11-AS: a novel regulator in human cancer proliferation and metastasis
Xue JY, Huang C, Wang W, Li HB, Sun Ming, Xie M
OncoTargets and Therapy 2018, 11:4387-4393
Published Date: 27 July 2018

Extracts and components of Ficus carica leaves suppress survival, cell cycle, and migration of triple-negative breast cancer MDA-MB-231 cells
Zhang Y, Wan Y, Huo B, Li B, Jin Y, Hu X
OncoTargets and Therapy 2018, 11:4377-4386
Published Date: 27 July 2018

Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer
Ding MN, Li Y, Yang Y, Zhu K, Che SL, Lin ZH, Chen LY
OncoTargets and Therapy 2018, 11:4367-4375
Published Date: 26 July 2018

The role of lncRNA CASC2 on prognosis of malignant tumors: a meta-analysis and bioinformatics
Yu L, Chen S, Bao H, Zhang W, Liao M, Liang Q, Cheng X
OncoTargets and Therapy 2018, 11:4355-4365
Published Date: 25 July 2018

18F-fluorodeoxyglucose positron emission tomography predicts lymph node responses to definitive chemoradiotherapy in esophageal squamous cell carcinoma patients

Zhu W, Zhang Y, Kong L, Huang Y, Zheng J, Wang R, Li M, Yu J
OncoTargets and Therapy 2018, 11:4345-4353
Published Date: 25 July 2018

Polymorphism of IFN-γ+874T/A associated with production of IFN-γ affects human papillomavirus susceptibility in rural women from Luohe, Henan, China
Zhang QW, Song JY, Yu JH, Sun MZ, Tang SY, Yang SZ, Cao LJ, Wang HF, Cui LN, Fu XH
OncoTargets and Therapy 2018, 11:4339-4344
Published Date: 25 July 2018

Identification of prognostic risk factors for esophageal adenocarcinoma using bioinformatics analysis
Dong Z, Wang J, Zhan T, Xu S
OncoTargets and Therapy 2018, 11:4327-4337
Published Date: 25 July 2018

Endoplasmic reticulum stress-mediated autophagy contributes to 5-ethylamino-9-diethylaminobenzo[a]phenoselenazinium-mediated photodynamic therapy via the PERK–eIF2α pathway
Chen J, Huang JH, Wang Z, Song X, Chen Z, Zeng Q, Zhou X, Zuo Z, Zhao S, Chen X, Kang J
OncoTargets and Therapy 2018, 11:4315-4325
Published Date: 24 July 2018

Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-κB, uPA activator, and MMP-9
Rajasinghe LD, Pindiprolu RH, Gupta SV
OncoTargets and Therapy 2018, 11:4301-4314
Published Date: 24 July 2018

Analysis of change in microRNA expression profiles of lung cancer A549 cells treated with Radix tetrastigma hemsleyani flavonoids
Liu P, Yang X, Zhang H, Pu J, Wei K
OncoTargets and Therapy 2018, 11:4283-4300
Published Date: 24 July 2018

Efficacy of bevacizumab versus epidermal growth factor receptor inhibitors for wild-type RAS metastatic colorectal cancer: a meta-analysis
Jiang W, Yu Q, Ning R, Zhao W, Wei C
OncoTargets and Therapy 2018, 11:4271-4281
Published Date: 24 July 2018

Effects of miRNAs on functions of breast cancer stem cells and treatment of breast cancer
Zhang Y, Xu B, Zhang XP
OncoTargets and Therapy 2018, 11:4263-4270
Published Date: 24 July 2018

Transcobalamin I: a novel prognostic biomarker of neoadjuvant chemotherapy in locally advanced hypopharyngeal squamous cell cancers
Wang Y, Yue C, Fang J, Gong L, Lian M, Wang R, Feng L, Ma H, Ma Z, Liu H
OncoTargets and Therapy 2018, 11:4253-4261
Published Date: 24 July 2018

Comparable efficacy and less toxicity of pegylated liposomal doxorubicin versus epirubicin for neoadjuvant chemotherapy of breast cancer: a case-control study
Dong M, Luo L, Ying X, Lu X, Shen J, Jiang Z, Wang L
OncoTargets and Therapy 2018, 11:4247-4252
Published Date: 23 July 2018

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients

Kim HJ, Jo MJ, Kim BR, Kim JL, Jeong YA, Na YJ, Park SH, Lee SY, Lee DH, Kim BH, Yoo YD, Oh SC
OncoTargets and Therapy 2018, 11:4233-4246
Published Date: 23 July 2018

CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway
Jia Y, Xiao Z, Gongsun X, Xin Z, Shang B, Chen G, Wang Z, Jiang W
OncoTargets and Therapy 2018, 11:4221-4232
Published Date: 20 July 2018

Matrix metalloproteinase-7 may serve as a novel biomarker for cervical cancer
Zhu L, Zheng X, Du Y, Xing Y, Xu K, Cui L
OncoTargets and Therapy 2018, 11:4207-4220
Published Date: 20 July 2018

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells
Yang L, Xie N, Huang J, Huang H, Xu S, Wang Z, Cai J
OncoTargets and Therapy 2018, 11:4197-4206
Published Date: 19 July 2018

Promoter methylation analysis of CDH1 and p14ARF genes in patients with urothelial bladder cancer
Bayramov B, Gunes S, Buyukalpelli R, Aydın O, Henkel R
OncoTargets and Therapy 2018, 11:4189-4196
Published Date: 19 July 2018

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway
Ge H, Liang C, Li Z, An D, Ren S, Yue C, Wu J
OncoTargets and Therapy 2018, 11:4177-4187
Published Date: 19 July 2018

Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis
Zheng T, Li D, He Z, Feng S, Zhao S
OncoTargets and Therapy 2018, 11:4167-4175
Published Date: 19 July 2018

Expression of protein disulfide isomerase A3 precursor in colorectal cancer
Yang Z, Liu J, Shi Q, Chao Y, Di Y, Sun J, Zhang J, Huang L, Guo H, He C
OncoTargets and Therapy 2018, 11:4159-4166
Published Date: 19 July 2018

Efficacy and safety assessment of apatinib in patients with advanced gastric cancer: a meta-analysis
Chen J, Wang J
OncoTargets and Therapy 2018, 11:4149-4158
Published Date: 19 July 2018

Progress in the treatment of solid tumors with apatinib: a systematic review
Zhao D, Hou H, Zhang X
OncoTargets and Therapy 2018, 11:4137-4147
Published Date: 19 July 2018

Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma
Xin Z, Xin G, Shi M, Song L, Wang Q, Jiang B, Liu X
OncoTargets and Therapy 2018, 11:4125-4136
Published Date: 19 July 2018

Pleiotropic functions of miR107 in cancer networks
Luo Z, Zheng Y, Zhang W
OncoTargets and Therapy 2018, 11:4113-4124
Published Date: 18 July 2018

Identification of potential core genes in triple negative breast cancer using bioinformatics analysis
Li MX, Jin LT, Wang TJ, Feng YJ, Pan CP, Zhao DM, Shao J
OncoTargets and Therapy 2018, 11:4105-4112
Published Date: 18 July 2018

TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma
Yu S, Xu T, Dai J, Ma M, Tang H, Chi Z, Si L, Cui C, Sheng X, Kong Y, Guo J
OncoTargets and Therapy 2018, 11:4097-4104
Published Date: 17 July 2018

miR-19b serves as a prognostic biomarker of breast cancer and promotes tumor progression through PI3K/AKT signaling pathway
Li C, Zhang J, Ma Z, Zhang F, Yu W
OncoTargets and Therapy 2018, 11:4087-4095
Published Date: 16 July 2018

MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42
Gu G, Wang L, Zhang J, Wang H, Tan T, Zhang G
OncoTargets and Therapy 2018, 11:4075-4085
Published Date: 16 July 2018
MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9)
Liu R, Wang F, Guo Y, Yang J, Chen S, Gao X, Wang X
OncoTargets and Therapy 2018, 11:4065-4073
Published Date: 16 July 2018

New PDL1 inhibitors for non-small cell lung cancer: focus on pembrolizumab
Bylicki O, Paleiron N, Rousseau-Bussac G, Chouaïd C
OncoTargets and Therapy 2018, 11:4051-4064
Published Date: 16 July 2018

Long-term progression-free survival of third-line apatinib in lung squamous cell carcinoma

Li X, Li X, Fang X, Yuan Y
OncoTargets and Therapy 2018, 11:4047-4050
Published Date: 16 July 2018

MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition
Hu F, Liu C, Xie F, Lin X, Yang J, Wang C, Huang Q
OncoTargets and Therapy 2018, 11:4035-4046
Published Date: 13 July 2018

Mutational analysis on gastric, duodenal, bone, and mediastinal lymph node metastases and blood from a case of primary lung adenocarcinoma

Yang X, Chen R, Wu C, Zhao W, Ji M
OncoTargets and Therapy 2018, 11:4029-4034
Published Date: 13 July 2018

Downregulation and DNA methylation of ECRG4 in gastric cancer
Deng P, Chang XJ, Gao ZM, Xu XY, Sun AQ, Li K, Dai DQ
OncoTargets and Therapy 2018, 11:4019-4028
Published Date: 13 July 2018

MFAP2 promotes epithelial–mesenchymal transition in gastric cancer cells by activating TGF-β/SMAD2/3 signaling pathway
Wang JK, Wang WJ, Cai HY, Du BB, Mai P, Zhang LJ, Ma W, Hu YG, Feng SF, Miao GY
OncoTargets and Therapy 2018, 11:4001-4017
Published Date: 12 July 2018

The effect of tubeimoside-1 on the proliferation, metastasis and apoptosis of oral squamous cell carcinoma in vitro
Wu T, Cui H, Xu Y, Du Q, Zhao E, Cao J, Nie L, Fu G, Ren A
OncoTargets and Therapy 2018, 11:3989-4000
Published Date: 10 July 2018

Overexpressed CDR1as functions as an oncogene to promote the tumor progression via miR-7 in non-small-cell lung cancer
Zhang X, Yang D, Wei Y
OncoTargets and Therapy 2018, 11:3979-3987
Published Date: 10 July 2018

Increased expression of antisense lncRNA SPINT1-AS1 predicts a poor prognosis in colorectal cancer and is negatively correlated with its sense transcript
Li C, Li W, Zhang YL, Zhang X, Liu T, Zhang Y, Yang YM, Wang LL, Pan HW, Ji J, Wang CX
OncoTargets and Therapy 2018, 11:3969-3978
Published Date: 10 July 2018

SIRT4 acts as a tumor suppressor in gastric cancer by inhibiting cell proliferation, migration, and invasion
Sun H, Huang D, Liu G, Jian F, Zhu J, Zhang L
OncoTargets and Therapy 2018, 11:3959-3968
Published Date: 10 July 2018

Immunohistochemical expression of hormone receptors, Ki-67, endoglin (CD105), claudins 3 and 4, MMP -2 and -9 in endometrial polyps and endometrial cancer type I
Peres GF, Spadoto-Dias D, Bueloni-Dias FN, Leite NJ, Elias LV, Domingues MA, Padovani CR, Dias R
OncoTargets and Therapy 2018, 11:3949-3958
Published Date: 9 July 2018

Role of chemotherapy with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI ) rechallenge in small cell transformation after EGFR-TKI failure: a case report

Lee S, Joo JH, Kwak MA, Sohn K, Chon SH
OncoTargets and Therapy 2018, 11:3943-3947
Published Date: 9 July 2018

Overexpression of DJ-1 correlates with aggressive clinicopathological characteristics and poor prognosis in malignant tumors: a meta-analysis
Wang Q, Li F, Shi W, Zhang Q, Wang J, Yan X, Chai L, Li M
OncoTargets and Therapy 2018, 11:3931-3942
Published Date: 9 July 2018

Integrated omics and gene expression analysis identifies the loss of metabolite–metabolite correlations in small cell lung cancer
Yu L, Li K, Xu Z, Cui G, Zhang X
OncoTargets and Therapy 2018, 11:3919-3929
Published Date: 6 July 2018

Predictive value of single nucleotide polymorphisms in XRCC1 for radiation-induced normal tissue toxicity
Zhao J, Zhi Z, Zhang M, Li Q, Li J, Wang X, Ma C
OncoTargets and Therapy 2018, 11:3901-3918
Published Date: 6 July 2018

MicroRNAs as potential biomarkers for diagnosis, therapy and prognosis of gastric cancer
Yuan HL, Wang T, Zhang KH
OncoTargets and Therapy 2018, 11:3891-3900
Published Date: 6 July 2018

The clinical usefulness of natural killer cell activity in patients with suspected or diagnosed prostate cancer: an observational cross-sectional study
Song W, Yu JW, Jeong BC, Seo SI, Jeon SS, Lee HM, Choi HY, Kang ES, Jeon HG
OncoTargets and Therapy 2018, 11:3883-3889
Published Date: 6 July 2018

Bortezomib-based therapy for transplant-ineligible East Asian patients with newly diagnosed mantle-cell lymphoma
Jin J, Okamoto R, Yoon SS, Shih LY, Zhu J, Liu T, Hong XN, Pei L, Rooney B, van de Velde H, Huang HQ
OncoTargets and Therapy 2018, 11:3869-3882
Published Date: 6 July 2018

Loss of miR-516a-3p mediates upregulation of ABCC5 in prostate cancer and drives its progression
Zhang H, Lian Z, Sun G, Liu R, Xu Y
OncoTargets and Therapy 2018, 11:3853-3867
Published Date: 6 July 2018

The role of histone lysine methyltransferase NSD3 in cancer
Han X, Piao L, Zhuang Q, Yuan X, Liu Z, He X
OncoTargets and Therapy 2018, 11:3847-3852
Published Date: 5 July 2018

miR-106b-5p inhibits the invasion and metastasis of colorectal cancer by targeting CTSA
Ni S, Weng W, Xu M, Wang Q, Tan C, Sun H, Wang L, Huang D, Du X, Sheng W
OncoTargets and Therapy 2018, 11:3835-3845
Published Date: 4 July 2018

Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2
Wan B, Zang Y, Wang L
OncoTargets and Therapy 2018, 11:3827-3833
Published Date: 4 July 2018

Tumor-associated macrophage-derived cytokines enhance cancer stem-like characteristics through epithelial–mesenchymal transition
Chen Y, Tan W, Wang C
OncoTargets and Therapy 2018, 11:3817-3826
Published Date: 4 July 2018

Silencing of c-jun decreases cell migration, invasion, and EMT in radioresistant human nasopharyngeal carcinoma cell line CNE-2R
Lin G, Yu B, Liang Z, Li L, Qu S, Chen K, Zhou L, Lu Q, Sun Y, Zhu X
OncoTargets and Therapy 2018, 11:3805-3815
Published Date: 4 July 2018

By blocking hexokinase-2 phosphorylation, limonin suppresses tumor glycolysis and induces cell apoptosis in hepatocellular carcinoma
Yao J, Liu J, Zhao W
OncoTargets and Therapy 2018, 11:3793-3803
Published Date: 3 July 2018

A prospective study on neoadjuvant chemoradiotherapy plus anti-EGFR monoclonal antibody followed by surgery for locally advanced cervical cancer
Lu H, Wu Y, Liu X, Jiang H, Pang Q, Peng L, Cheng J, Deng S, Gu J, Zhao R, Hu X, Chen C, Yu J
OncoTargets and Therapy 2018, 11:3785-3792
Published Date: 2 July 2018

SIL1 functions as an oncogene in glioma by AKT/mTOR signaling pathway
Xu H, Xu S, Zhang R, Xin T, Pang Q
OncoTargets and Therapy 2018, 11:3775-3783
Published Date: 2 July 2018

Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer
Wang S, Zhang Z, Qian W, Ji D, Wang Q, Ji B, Zhang Y, Zhang C, Sun Y, Zhu C, Sun Y
OncoTargets and Therapy 2018, 11:3765-3774
Published Date: 2 July 2018

Colorectal neoplasia differentially expressed: a long noncoding RNA with an imperative role in cancer
Dai M, Li S, Qin X
OncoTargets and Therapy 2018, 11:3755-3763
Published Date: 29 June 2018

Primary effusion lymphoma: current perspectives
Narkhede M, Arora S, Ujjani C
OncoTargets and Therapy 2018, 11:3747-3754
Published Date: 28 June 2018

IRX-2 natural cytokine biologic for immunotherapy in patients with head and neck cancers
Wolf GT, Moyer JS, Kaplan MJ, Newman JG, Egan JE, Berinstein NL, Whiteside TL
OncoTargets and Therapy 2018, 11:3731-3746
Published Date: 28 June 2018

Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma
Dong M, Miao L, Zhang F, Li S, Han J, Yu R, Qie S
OncoTargets and Therapy 2018, 11:3721-3729
Published Date: 28 June 2018

Updates on the clinical diagnosis and management of ocular sebaceous carcinoma: a brief review of the literature
Xu YF, Li F, Jia RB, Fan XQ
OncoTargets and Therapy 2018, 11:3713-3720
Published Date: 27 June 2018

Targeted therapy and immunotherapy for platinum-refractory advanced ovarian adenosquamous carcinoma: a case report

Li A, Sun S, Song T, Li X, Cheng W, Yao R, Zhang D, Cai Z, Zhang J, Zhai D, Yu C
OncoTargets and Therapy 2018, 11:3705-3711
Published Date: 27 June 2018

Chemotherapy with or without pemetrexed as second-line regimens for advanced non-small-cell lung cancer patients who have progressed after first-line EGFR TKIs: a systematic review and meta-analysis
Li ZH, Guo HY, Lu YY, Hu JX, Luo HT, Gu WG
OncoTargets and Therapy 2018, 11:3697-3703
Published Date: 27 June 2018

Impact of smoking on efficacy of PD-1/PD-L1 inhibitors in non-small cell lung cancer patients: a meta-analysis
Li B, Huang X, Fu L
OncoTargets and Therapy 2018, 11:3691-3696
Published Date: 26 June 2018

An uncommon granulocytic sarcoma of the breast: a case report and literature review

Zhai J, Kong X, Yang X, Gao J, Xuan L, Wang X, Wang J, Fang Y
OncoTargets and Therapy 2018, 11:3685-3690
Published Date: 25 June 2018

CAT3, a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independently of O6-methylguanine DNA methyltransferase expression
Ji M, Wang L, Chen J, Xue N, Wang C, Lai F, Wang R, Yu SS, Jin J, Chen X
OncoTargets and Therapy 2018, 11:3671-3684
Published Date: 25 June 2018

Prognostic impact of the number of lymph nodes examined in different stages of colorectal mucinous adenocarcinoma
Ma Y, Luo YQ, Lin N, Lv YZ, Zhou Y, Li B, Han KN, Jiang S, Gao JJ
OncoTargets and Therapy 2018, 11:3659-3670
Published Date: 25 June 2018

lincROR influences the stemness and crizotinib resistance in EML–ALK+ non-small-cell lung cancer cells
Yang Y, Huang J, Xie N, Huang H, Xu S, Cai J, Qi S
OncoTargets and Therapy 2018, 11:3649-3657
Published Date: 22 June 2018

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma
Wang H, Fang ZL, Zhang GH, Ma X
OncoTargets and Therapy 2018, 11:3637-3647
Published Date: 21 June 2018

MYO5A inhibition by miR-145 acts as a predictive marker of occult neck lymph node metastasis in human laryngeal squamous cell carcinoma
Zhao X, Zhang W, Ji W
OncoTargets and Therapy 2018, 11:3619-3635
Published Date: 21 June 2018

A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1
Zhao XZ, Wu XH
OncoTargets and Therapy 2018, 11:3609-3617
Published Date: 21 June 2018

Whole-body MRI versus 18F-FDG PET/CT for pretherapeutic assessment and staging of lymphoma: a meta-analysis
Wang D, Huo Y, Chen S, Wang H, Ding Y, Zhu X, Ma C
OncoTargets and Therapy 2018, 11:3597-3608
Published Date: 20 June 2018

lncRNA H19 predicts poor prognosis in patients with melanoma and regulates cell growth, invasion, migration and epithelial–mesenchymal transition in melanoma cells
Shi G, Li H, Gao F, Tan Q
OncoTargets and Therapy 2018, 11:3583-3595
Published Date: 20 June 2018

Impact of RNA integrity and blood sample storage conditions on the gene expression analysis
Shen YT, Li R, Tian F, Chen ZZ, Lu N, Bai YF, Ge QY, Lu ZH
OncoTargets and Therapy 2018, 11:3573-3581
Published Date: 20 June 2018

Clinicopathological and prognostic significance of FoxM1 in hepatocellular carcinoma patients: a meta-analysis
Liang C, Zhao J, Ge H, Li G, Wu J
OncoTargets and Therapy 2018, 11:3561-3571
Published Date: 19 June 2018

The role of radioactive iodine therapy in papillary thyroid cancer: an observational study based on SEER
Tang J, Kong D, Cui Q, Wang K, Zhang D, Liao X, Gong Y, Wu G
OncoTargets and Therapy 2018, 11:3551-3560
Published Date: 19 June 2018

Prognostic value of miR-17-5p in cancers: a meta-analysis
Kong W, Cheng Y, Liang H, Chen Q, Xiao C, Li K, Huang Z, Zhang J
OncoTargets and Therapy 2018, 11:3541-3549
Published Date: 19 June 2018

Multiple biological functions of transcription factor 21 in the development of various cancers
Jiang X, Yang Z
OncoTargets and Therapy 2018, 11:3533-3539
Published Date: 19 June 2018

Curcumin suppresses the progression of laryngeal squamous cell carcinoma through the upregulation of miR-145 and inhibition of the PI3K/Akt/mTOR pathway
Zhu X, Zhu R
OncoTargets and Therapy 2018, 11:3521-3531
Published Date: 19 June 2018

The prognosis for patients with newly diagnosed glioblastoma receiving bevacizumab combination therapy: a meta-analysis
Liao KL, Huang S, Wu YP
OncoTargets and Therapy 2018, 11:3513-3520
Published Date: 19 June 2018

Combined small-cell lung carcinoma
Qin J, Lu H
OncoTargets and Therapy 2018, 11:3505-3511
Published Date: 19 June 2018

Association between common polymorphisms in ERCC gene and prognosis of osteosarcoma in patients treated with chemotherapy: a meta-analysis
Li C, Yu X, Guo D, Liu G, Zhang K, Teng Q, Lin H
OncoTargets and Therapy 2018, 11:3495-3504
Published Date: 18 June 2018

Downregulation of ribophorin II suppresses tumor growth, migration, and invasion of nasopharyngeal carcinoma
Hong F, Li Y, Ni H, Li J
OncoTargets and Therapy 2018, 11:3485-3494
Published Date: 15 June 2018

STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway
Wang N, He X, Zhou R, Jia G, Qiao Q
OncoTargets and Therapy 2018, 11:3475-3484
Published Date: 15 June 2018

MALAT1 silencing suppresses prostate cancer progression by upregulating miR-1 and downregulating KRAS
Chang J, Xu W, Du X, Hou J
OncoTargets and Therapy 2018, 11:3461-3473
Published Date: 15 June 2018

The association of pretreatment serum albumin with outcomes in bladder cancer: a meta-analysis
Li J, Cheng Y, Liu G, Ji Z
OncoTargets and Therapy 2018, 11:3449-3459
Published Date: 15 June 2018

Comparison of the prognosis of neoadjuvant chemoradiotherapy treatment with surgery alone in esophageal carcinoma: a meta-analysis
Ma HF, Lv GX, Cai ZF, Zhang DH
OncoTargets and Therapy 2018, 11:3441-3447
Published Date: 14 June 2018

Effectiveness of lomustine and bevacizumab in progressive glioblastoma: a meta-analysis
Song J, Xue YQ, Zhao MM, Xu P
OncoTargets and Therapy 2018, 11:3435-3439
Published Date: 13 June 2018

Reformulating acute myeloid leukemia: liposomal cytarabine and daunorubicin (CPX-351) as an emerging therapy for secondary AML
Chen EC, Fathi AT, Brunner AM
OncoTargets and Therapy 2018, 11:3425-3434
Published Date: 12 June 2018

Twenty-gene-based prognostic model predicts lung adenocarcinoma survival
Zhao K, Li Z, Tian H
OncoTargets and Therapy 2018, 11:3415-3424
Published Date: 12 June 2018

Efficacy and safety of sorafenib versus apatinib in the treatment of intermediate and advanced hepatocellular carcinoma: a comparative retrospective study
Wang Y, Gou Q, Xu R, Chen X, Zhou Z
OncoTargets and Therapy 2018, 11:3407-3413
Published Date: 12 June 2018

Identification of CD24 as a marker for tumorigenesis of melanoma
Tang MR, Guo JY, Wang D, Xu N
OncoTargets and Therapy 2018, 11:3401-3406
Published Date: 12 June 2018

Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer
Huang G, Zhu G
OncoTargets and Therapy 2018, 11:3395-3400
Published Date: 11 June 2018

Expression and functional characterization of FOXM1 in non-small cell lung cancer
Zhang Y, Qiao W, Shan L
OncoTargets and Therapy 2018, 11:3385-3393
Published Date: 11 June 2018

Prognostic value of spleen tyrosine kinase in human solid tumors
Ni B, Li S, Liu Y, Huang Y, Li Z
OncoTargets and Therapy 2018, 11:3377-3384
Published Date: 8 June 2018

Meta-analysis of segmentectomy versus wedge resection in stage IA non-small-cell lung cancer
Xue WF, Duan GC, Zhang XP, Zhang H, Zhao QT, Xin ZF
OncoTargets and Therapy 2018, 11:3369-3375
Published Date: 7 June 2018

Effect of AQP-5 silencing by siRNA interference on chemosensitivity of breast cancer cells
Li X, Pei B, Wang H, Tang C, Zhu W, Jin F
OncoTargets and Therapy 2018, 11:3359-3368
Published Date: 6 June 2018

Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics
Liu X, Weng Y, Liu P, Sui Z, Zhou L, Huang Y, Zhang L, Zhang Y, Tan X
OncoTargets and Therapy 2018, 11:3345-3357
Published Date: 6 June 2018

Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer
Kobayashi K, Naoki K, Manabe T, Masuzawa K, Hasegawa H, Yasuda H, Kawada I, Soejima K, Betsuyaku T
OncoTargets and Therapy 2018, 11:3335-3343
Published Date: 6 June 2018

Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling
Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y, Kan Q
OncoTargets and Therapy 2018, 11:3323-3333
Published Date: 6 June 2018

Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway
Al-Obeed O, Vaali-Mohammed MA, Eldehna WM, Al-Khayal K, Mahmood A, Abdel-Aziz HA, Zubaidi A, Alafeefy A, Abdulla M, Ahmad R
OncoTargets and Therapy 2018, 11:3313-3322
Published Date: 5 June 2018

Overexpression of CLEC3A promotes tumor progression and poor prognosis in breast invasive ductal cancer
Ni J, Peng Y, Yang F, Xi X, Huang X, He C
OncoTargets and Therapy 2018, 11:3303-3312
Published Date: 5 June 2018

Effects of the combination of As2O3 and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1

Zhao C, Wang M, Liu Y, Liang YJ, Han L, Chen C
OncoTargets and Therapy 2018, 11:3293-3301
Published Date: 1 June 2018

Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1
Chen Y, Zhang F, Zhao Y, He K, Zheng X, Pan Y, Shao D, Shang P, Yang Y, Zhang D, Xie Y, Yao X, Chen L, Li J, Zhang X
OncoTargets and Therapy 2018, 11:3281-3292
Published Date: 1 June 2018

Association of VDR gene TaqI polymorphism with the susceptibility to prostate cancer in Asian population evaluated by an updated systematic meta-analysis
Chen L, Wei J, Zhang S, Lou Z, Wang X, Ren Y, Qi H, Xie Z, Chen Y, Chen F, Wu Q, Fan X, Xu H, Huang S, Weng G
OncoTargets and Therapy 2018, 11:3267-3280
Published Date: 31 May 2018

A new apatinib microcrystal formulation enhances the effect of radiofrequency ablation treatment on hepatocellular carcinoma

Xie H, Tian S, Yu H, Yang X, Liu J, Wang H, Feng F, Guo Z
OncoTargets and Therapy 2018, 11:3257-3265
Published Date: 31 May 2018

Prognostic role of plasma mammaglobin A expression in breast carcinoma patients: a meta-analysis
Hu YY, Liu P, Wu D, Jiang YH
OncoTargets and Therapy 2018, 11:3245-3255
Published Date: 30 May 2018

Prognostic significance of galectin-1 and vasculogenic mimicry in patients with gastric cancer
You X, Wang Y, Wu J, Liu Q, Chen D, Tang D, Wang D
OncoTargets and Therapy 2018, 11:3237-3244
Published Date: 29 May 2018

Association between KIF1B (rs17401966) polymorphism and hepatocellular carcinoma susceptibility: a meta-analysis
Zhang Y, Zeng X, Lu H, Ji H, Lu L, Liu P, Hong R, Li Y
OncoTargets and Therapy 2018, 11:3225-3235
Published Date: 29 May 2018

Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression
Li S, Wen D, Che S, Cui Z, Sun Y, Ren H, Hao J
OncoTargets and Therapy 2018, 11:3215-3223
Published Date: 6 June 2018

Periostin overexpression is associated with worse prognosis in nasopharyngeal carcinoma from endemic area: a cohort study
Wei YC, Yang SF, Chang SL, Chen TJ, Lee SW, Chen HS, Lin LC, Li CF
OncoTargets and Therapy 2018, 11:3205-3213
Published Date: 29 May 2018

Knockdown of KIF26B inhibits breast cancer cell proliferation, migration, and invasion
Gu S, Liang H, Qi D, Mao L, Mao G, Qian L, Zhang S
OncoTargets and Therapy 2018, 11:3195-3203
Published Date: 29 May 2018

Emerging role of long non-coding RNAs in cisplatin resistance
Hu Y, Zhu QN, Deng JL, Li ZX, Wang G, Zhu YS
OncoTargets and Therapy 2018, 11:3185-3194
Published Date: 28 May 2018

A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature

Duan M, Xing H, Wang K, Niu C, Jiang C, Zhang L, Ezzat S, Zhang L
OncoTargets and Therapy 2018, 11:3179-3184
Published Date: 28 May 2018

Recent advances on the progressive mechanism and therapy in castration-resistant prostate cancer
Wang K, Ruan H, Xu T, Liu L, Liu D, Yang H, Zhang X, Chen K
OncoTargets and Therapy 2018, 11:3167-3178
Published Date: 28 May 2018

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells
Wang Z, Luo C, Wang H, Yan X, Liu W, Meng Z
OncoTargets and Therapy 2018, 11:3159-3166
Published Date: 28 May 2018

High SRPX2 protein expression predicts unfavorable clinical outcome in patients with prostate cancer
Zhang M, Li X, Fan Z, Zhao J, Liu S, Zhang M, Li H, Goscinski MA, Fan H, Suo Z
OncoTargets and Therapy 2018, 11:3149-3157
Published Date: 28 May 2018

miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells
Chen K, Chen Y, Chen Z, Shi Y, He Z, Ding B, Wang C, Yu L
OncoTargets and Therapy 2018, 11:3141-3147
Published Date: 25 May 2018

Construction of a specific SVM classifier and identification of molecular markers for lung adenocarcinoma based on lncRNA-miRNA-mRNA network
Zhao J, Cheng W, He X, Liu Y, Li J, Sun J, Li J, Wang F, Gao Y
OncoTargets and Therapy 2018, 11:3129-3140
Published Date: 25 May 2018

The incidence and predictors of symptomatic venous thromboembolism associated with peripherally inserted central catheters in patients with nasopharyngeal carcinoma
Liang YJ, He Y, Li JM, Chen LM, Chen LP, Wang C, Ji L, Li ZX, Tang LQ, Chen QY, Fan YY, Hu W
OncoTargets and Therapy 2018, 11:3119-3127
Published Date: 25 May 2018

Overexpression of MCPH1 inhibits the migration and invasion of lung cancer cells
Wu X, Liu W, Liu X, Ai Q, Yu J
OncoTargets and Therapy 2018, 11:3111-3117
Published Date: 25 May 2018

Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma
Lin MH, Lv D, Zheng YL, Wu ML, Xu C, Zhang Q, Wu LH
OncoTargets and Therapy 2018, 11:3101-3110
Published Date: 25 May 2018

Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis
Liu X, Zhao Y, Zhang W, Gao Y, Huo M, Liu M, Xiao Z, Liang S, Xu N, Zhu H
OncoTargets and Therapy 2018, 11:3087-3100
Published Date: 24 May 2018

An integrated analysis of key microRNAs, regulatory pathways and clinical relevance in bladder cancer
Li D, Hao X, Song Y
OncoTargets and Therapy 2018, 11:3075-3085
Published Date: 24 May 2018

Gene expression and prognosis of NOX family members in gastric cancer
You X, Ma M, Hou G, Hu Y, Shi X
OncoTargets and Therapy 2018, 11:3065-3074
Published Date: 24 May 2018

Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic colorectal cancer
Cicero G, De Luca R, Dieli F
OncoTargets and Therapy 2018, 11:3059-3063
Published Date: 24 May 2018

The synergistic effects of Apatinib combined with cytotoxic chemotherapeutic agents on gastric cancer cells and in a fluorescence imaging gastric cancer xenograft model
Feng JH, Qin SK
OncoTargets and Therapy 2018, 11:3047-3057
Published Date: 24 May 2018

High expression of USP22 predicts poor prognosis and advanced clinicopathological features in solid tumors: a meta-analysis
Yang XH, Zang H, Luo Y, Wu J, Fang Z, Zhu W, Li Y
OncoTargets and Therapy 2018, 11:3035-3046
Published Date: 23 May 2018

LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway
Ke J, Ma P, Chen J, Qin J, Qian H
OncoTargets and Therapy 2018, 11:3025-3033
Published Date: 22 May 2018

Expression of HSP90AA1/HSPA8 in hepatocellular carcinoma patients with depression
Xiang X, You XM, Li LQ
OncoTargets and Therapy 2018, 11:3013-3023
Published Date: 22 May 2018

The role of HIF-1α in chemo-/radioresistant tumors
Xia Y, Jiang L, Zhong T
OncoTargets and Therapy 2018, 11:3003-3011
Published Date: 22 May 2018

The methylation profiles of PRDM promoters in non–small cell lung cancer
Tan SX, Hu RC, Xia Q, Tan YL, Liu JJ, Gan GX, Wang LL
OncoTargets and Therapy 2018, 11:2991-3002
Published Date: 22 May 2018

Resveratrol inhibits the proliferation of A549 cells by inhibiting the expression of COX-2
Li X, Li F, Wang FF, Li JF, Lin CZ, Du JX
OncoTargets and Therapy 2018, 11:2981-2989
Published Date: 22 May 2018

Intra-arterial chemotherapy improved survival of stage 2–3 gallbladder cancer after curative resection
Chen C, Feng W, Zheng Y, Bao Y, Feng M
OncoTargets and Therapy 2018, 11:2975-2979
Published Date: 22 May 2018

Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma
Liu J, Wu Q, Wang Y, Wei Y, Wu H, Duan L, Zhang Q, Wu Y
OncoTargets and Therapy 2018, 11:2963-2973
Published Date: 22 May 2018

Downregulation of STARD8 in gastric cancer and its involvement in gastric cancer progression
Zhang S, Chang X, Ma J, Chen J, Zhi Y, Li Z, Dai D
OncoTargets and Therapy 2018, 11:2955-2961
Published Date: 21 May 2018

Triclosan treatment decreased the antitumor effect of sorafenib on hepatocellular carcinoma cells
Wu M, Zhao G, Zhuang X, Zhang T, Zhang C, Zhang W, Zhang Z
OncoTargets and Therapy 2018, 11:2945-2954
Published Date: 18 May 2018

Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells
Li Z, Zhu C, An B, Chen Y, He X, Qian L, Lan L, Li S
OncoTargets and Therapy 2018, 11:2937-2944
Published Date: 18 May 2018

Downregulation of PDIA3 inhibits proliferation and invasion of human acute myeloid leukemia cells
Ye Q, Fu P, Dou J, Wang N
OncoTargets and Therapy 2018, 11:2925-2935
Published Date: 17 May 2018
miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R
Liu N, Yang H, Wang H
OncoTargets and Therapy 2018, 11:2911-2923
Published Date: 17 May 2018

High neutrophil to lymphocyte ratio and decreased CD69+NK cells represent a phenotype of high risk in early-stage breast cancer patients
Mandó P, Rizzo M, Roberti MP, Juliá EP, Pampena MB, Pérez de la Puente C, Loza CM, Ponce C, Nadal J, Coló FA, Mordoh J, Levy EM
OncoTargets and Therapy 2018, 11:2901-2910
Published Date: 17 May 2018

Bacillus Calmette–Guérin and anti-PD-L1 combination therapy boosts immune response against bladder cancer
Wang Y, Liu J, Yang X, Liu Y, Liu Y, Li Y, Sun L, Yang X, Niu H
OncoTargets and Therapy 2018, 11:2891-2899
Published Date: 16 May 2018

RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway
Li C, Jiang X, Lin B, Hong H, Zhu S, Jiang L, Wang X, Tang N, She F, Chen Y
OncoTargets and Therapy 2018, 11:2875-2890
Published Date: 16 May 2018

Leaflet manual of external beam radiation therapy for hepatocellular carcinoma: a review of the indications, evidences, and clinical trials
Rim CH, Yoon WS
OncoTargets and Therapy 2018, 11:2865-2874
Published Date: 16 May 2018

circSMAD2 inhibits the epithelial–mesenchymal transition by targeting miR-629 in hepatocellular carcinoma
Zhang XW, Luo P, Jing W, Zhou H, Liang CZ, Tu JC
OncoTargets and Therapy 2018, 11:2853-2863
Published Date: 16 May 2018

NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation
Li T, Sun R, Lu MD, Chang J, Meng X, Wu H
OncoTargets and Therapy 2018, 11:2843-2852
Published Date: 15 May 2018

Advances of exosome in the development of ovarian cancer and its diagnostic and therapeutic prospect
Shen J, Zhu X, Fei J, Shi P, Yu S, Zhou J
OncoTargets and Therapy 2018, 11:2831-2841
Published Date: 15 May 2018

Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis
Zhou X, Huang X, Liang S, Tang S, Wu S, Huang T, Mo Z, Wang Q
OncoTargets and Therapy 2018, 11:2815-2830
Published Date: 15 May 2018

5-Azacytidine treatment induces demethylation of DAPK1 and MGMT genes and inhibits growth in canine mammary gland tumor cells
Ren XL, Li HT, Song XY, Wu YH, Liu Y
OncoTargets and Therapy 2018, 11:2805-2813
Published Date: 15 May 2018

Long noncoding RNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression
Diao L, Wang S, Sun Z
OncoTargets and Therapy 2018, 11:2797-2804
Published Date: 14 May 2018

Impact of targeting transforming growth factor β-2 with antisense OT-101 on the cytokine and chemokine profile in patients with advanced pancreatic cancer
D'Cruz OJ, Qazi S, Hwang L, Ng K, Trieu V
OncoTargets and Therapy 2018, 11:2779-2796
Published Date: 14 May 2018

Peritoneal carcinomatosis index as a predictor of diaphragmatic involvement in stage III and IV ovarian cancer

Llueca A, Serra A, Herraiz JL, Rivadulla I, Gomez-Quiles L, Gilabert-Estelles J, Escrig J
OncoTargets and Therapy 2018, 11:2771-2777
Published Date: 15 May 2018

ZNF418 overexpression protects against gastric carcinoma and prompts a good prognosis
Hui H, Hu Z, Jiang C, Wu J, Gao Y, Wang X
OncoTargets and Therapy 2018, 11:2763-2770
Published Date: 11 May 2018

Upregulation of circ_0066444 promotes the proliferation, invasion, and migration of gastric cancer cells
Rong D, Dong C, Fu K, Wang H, Tang W, Cao H
OncoTargets and Therapy 2018, 11:2753-2761
Published Date: 11 May 2018

Leucine-rich alpha-2-glycoprotein-1 is up-regulated in colorectal cancer and is a tumor promoter
Zhang Q, Huang R, Tang Q, Yu Y, Huang Q, Chen Y, Wang G, Wang X
OncoTargets and Therapy 2018, 11:2745-2752
Published Date: 11 May 2018

Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo
Ling Z, Guan H, You Z, Wang C, Hu L, Zhang L, Wang Y, Chen S, Xu B, Chen M
OncoTargets and Therapy 2018, 11:2735-2743
Published Date: 11 May 2018

Association between angiogenesis and cytotoxic signatures in the tumor microenvironment of gastric cancer
Feng Y, Dai Y, Gong Z, Cheng JN, Zhang L, Sun C, Zeng X, Jia Q, Zhu B
OncoTargets and Therapy 2018, 11:2725-2733
Published Date: 10 May 2018

Association between NR5A2 and the risk of pancreatic cancer, especially among Caucasians: a meta-analysis of case–control studies
Chen Q, Yuan H, Shi GD, Wu Y, Liu D, Lin YT, Chen L, Ge W, Jiang K, Miao Y
OncoTargets and Therapy 2018, 11:2709-2723
Published Date: 9 May 2018

Clinical relevance of lysyl oxidase-like 2 and functional mechanisms in glioma
Du XG, Zhu MJ
OncoTargets and Therapy 2018, 11:2699-2708
Published Date: 9 May 2018

Traditional Chinese medicine Astragalus polysaccharide enhanced antitumor effects of the angiogenesis inhibitor apatinib in pancreatic cancer cells on proliferation, invasiveness, and apoptosis
Wu J, Wang J, Su Q, Ding W, Li T, Yu J, Cao B
OncoTargets and Therapy 2018, 11:2685-2698
Published Date: 9 May 2018

Delivery of bevacizumab by intracranial injection: assessment in glioma model
Liu YX, Liu WJ, Zhang HR, Zhang ZW
OncoTargets and Therapy 2018, 11:2673-2683
Published Date: 8 May 2018

Influence of different ex vivo cell culture methods on the proliferation and anti-tumor activity of cytokine-induced killer cells from gastric cancer patients
Shi B, Sun AX, Zhang XR
OncoTargets and Therapy 2018, 11:2657-2672
Published Date: 8 May 2018

Effect of first-line endocrine therapy in patients with hormone-sensitive advanced breast cancer: a network meta-analysis
Zhang T, Feng F, Zhao W, Tian J, Yao Y, Zhou C, Dong S, Wang C, Zang C, Lv Q, Sun C
OncoTargets and Therapy 2018, 11:2647-2656
Published Date: 8 May 2018

The utilization of next-generation sequencing to detect somatic mutations and predict clinical prognosis of Chinese non-small cell lung cancer patients
Cao L, Long L, Li M, Yang H, Deng P, Mao X, Xiang J, Li B, Zhang T, Hu C
OncoTargets and Therapy 2018, 11:2637-2646
Published Date: 8 May 2018

Predicting initial margin status in breast cancer patients during breast-conserving surgery
Pan Z, Zhu L, Li Q, Lai J, Peng J, Su F, Li S, Chen K
OncoTargets and Therapy 2018, 11:2627-2635
Published Date: 8 May 2018

Are ovarian cancer stem cells the target for innovative immunotherapy?
Wang L, Xu T, Cui M
OncoTargets and Therapy 2018, 11:2615-2626
Published Date: 8 May 2018

A 5-serum miRNA panel for the early detection of colorectal cancer
Guo S, Zhang J, Wang B, Zhang B, Wang X, Huang L, Liu H, Jia B
OncoTargets and Therapy 2018, 11:2603-2614
Published Date: 8 May 2018

Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells
Wu S, Yang Y, Li F, Huang L, Han Z, Wang G, Yu H, Li H
OncoTargets and Therapy 2018, 11:2593-2601
Published Date: 8 May 2018

WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling
Han Q, Kremerskothen J, Lin X, Zhang X, Rong X, Zhang D, Wang E
OncoTargets and Therapy 2018, 11:2581-2591
Published Date: 8 May 2018

Partial stereotactic ablative boost radiotherapy in bulky non-small cell lung cancer: a retrospective study

Bai Y, Gao XS, Qin SB, Chen JY, Su MM, Liu Q, Qin XB, Ma MW, Zhao B, Gu XB, Xie M, Cui M, Qi X, Li XY
OncoTargets and Therapy 2018, 11:2571-2579
Published Date: 8 May 2018

Fatal hemoptysis in patients with advanced esophageal cancer treated with apatinib

Wang W, Zhang L, Xie Y, Zhen TC, Su GZ, Zang Q
OncoTargets and Therapy 2018, 11:2565-2570
Published Date: 7 May 2018

Perioperative chemotherapy with pemetrexed and cisplatin for pulmonary large-cell neuroendocrine carcinoma: a case report and literature review
Tang H, Wang HY, Xi SY, He CY, Chang YX, Wang QM, Wu YF
OncoTargets and Therapy 2018, 11:2557-2563
Published Date: 7 May 2018

Patterns of local failures and suggestions for reduction of clinical target volume for nasopharyngeal carcinoma patients without cervical lymph node metastasis

Li Y, Ou X, Shen C, Xu T, Li W, Hu C
OncoTargets and Therapy 2018, 11:2545-2555
Published Date: 7 May 2018

Prognostic factors for operable biliary tract cancer: serum levels of lactate dehydrogenase, a strong association with survival
Ma L, Qiu JR, Zhang YD, Qiu TZ, Wang B, Chen WS, Li X, Sun J, Wang K, Li XC, Gu YH, Shu YQ, Chen XF
OncoTargets and Therapy 2018, 11:2533-2543
Published Date: 4 May 2018

Low circulating total adiponectin, especially its non-high-molecular weight fraction, represents a promising risk factor for colorectal cancer: a meta-analysis
Lu W, Huang Z, Li N, Liu H
OncoTargets and Therapy 2018, 11:2519-2531
Published Date: 4 May 2018

Clinical and radiological characteristics of central pulmonary adenocarcinoma: a comparison with central squamous cell carcinoma and small cell lung cancer and the impact on treatment response
Wang Z, Li M, Huang Y, Ma L, Zhu H, Kong L, Yu J
OncoTargets and Therapy 2018, 11:2509-2517
Published Date: 4 May 2018

The genetic association between iNOS and eNOS polymorphisms and gastric cancer risk: a meta-analysis
Zhu Y, Jiang HG, Chen ZH, Lu BH, Li J, Peng YP, Shen XN
OncoTargets and Therapy 2018, 11:2497-2507
Published Date: 3 May 2018

Pretreatment hematologic markers as prognostic predictors of gastroenteropancreatic neuroendocrine tumors: a systematic review and meta-analysis
Zhou Y, Li D, Lin Y, Yu M, Lu X, Jian Z, Na N, Hou B
OncoTargets and Therapy 2018, 11:2489-2496
Published Date: 1 May 2018

UCA1 promotes cell proliferation and invasion and inhibits apoptosis through regulation of the miR129–SOX4 pathway in renal cell carcinoma
Liu Q, Li Y, Lv W, Zhang G, Tian X, Li X, Cheng H, Zhu C
OncoTargets and Therapy 2018, 11:2475-2487
Published Date: 1 May 2018

Rechallenge of oxaliplatin-containing regimens in the third- or later-line therapy for patients with heavily treated metastatic colorectal cancer
Yang Q, Huang YY, Jiang ZM, Wang HZ, Li WY, Zhang B, Xie DR
OncoTargets and Therapy 2018, 11:2467-2473
Published Date: 1 May 2018

Comprehensive analysis of a long noncoding RNA-associated competing endogenous RNA network in colorectal cancer
Fan Q, Liu B
OncoTargets and Therapy 2018, 11:2453-2466
Published Date: 1 May 2018

The CXCL12 rs1801157 polymorphism and risk of colorectal cancer: a meta-analysis
Xu K, Dai H, Wang S, Zhang J, Liu T
OncoTargets and Therapy 2018, 11:2445-2452
Published Date: 1 May 2018

A favorable outcome of advanced dermatofibrosarcoma protuberans under treatment with sunitinib after imatinib failure
Xiao W, Que Y, Peng RQ, Ding Y, Zhao JJ, Wen XZ, Weng DS, Zhang XS, Guan YX, Zhang X
OncoTargets and Therapy 2018, 11:2439-2443
Published Date: 1 May 2018

Role of miR-613 as a tumor suppressor in glioma cells by targeting SOX9
Sang S, Liu X, Sun D
OncoTargets and Therapy 2018, 11:2429-2438
Published Date: 30 April 2018

A meta-analytic review of the association between two common SNPs in miRNAs and lung cancer susceptibility
Xiao S, Sun S, Long W, Kuang S, Liu Y, Huang H, Zhou J, Zhou Y, Lu X
OncoTargets and Therapy 2018, 11:2419-2427
Published Date: 30 April 2018

Peptide SA12 inhibits proliferation of breast cancer cell lines MCF-7 and MDA-MB-231 through G0/G1 phase cell-cycle arrest
Yang LF, Liu HR, Long M, Wang X, Lin F, Gao ZW, Zhang HZ
OncoTargets and Therapy 2018, 11:2409-2417
Published Date: 30 April 2018

A Phase Ib study of ruxolitinib + gemcitabine ± nab-paclitaxel in patients with advanced solid tumors
Bauer TM, Patel MR, Forero-Torres A, George TJ Jr, Assad A, Du Y, Hurwitz H
OncoTargets and Therapy 2018, 11:2399-2407
Published Date: 30 April 2018

Role of Beclin1 expression in patients with hepatocellular carcinoma: a meta-analysis
Liang C, Li W, Ge H, Zhang KT, Li GM, Wu J
OncoTargets and Therapy 2018, 11:2387-2397
Published Date: 27 April 2018

MicroRNA-328 inhibits migration and epithelial–mesenchymal transition by targeting CD44 in nasopharyngeal carcinoma cells
Lin CH, Chiang MC, Chen YJ
OncoTargets and Therapy 2018, 11:2375-2385
Published Date: 27 April 2018


LDH-A promotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer


Zhang Y, Lin S, Chen Y, Yang F, Liu S
OncoTargets and Therapy 2018, 11:2363-2373
Published Date: 27 April 2018

Retrospective study of survival in human papillomavirus-negative oropharyngeal squamous cell carcinoma treated with primary surgery and associated prognostic factors
Yuan Y, Wang L, Li QX, Zhang JY, Xu ZX, Guo CB
OncoTargets and Therapy 2018, 11:2355-2362
Published Date: 27 April 2018

The effect of icotinib combined with chemotherapy in untreated non-small-cell lung cancer that harbored EGFR-sensitive mutations in a real-life setting: a retrospective analysis
Wang LL, Li Y, Li LC, Wu ZJ, Yang D, Ma HW, Wang DL
OncoTargets and Therapy 2018, 11:2345-2353
Published Date: 26 April 2018

Combination of long noncoding RNA MALAT1 and carcinoembryonic antigen for the diagnosis of malignant pleural effusion caused by lung cancer
Wang WW, Zhou XL, Song YJ, Yu CH, Zhu WG, Tong YS
OncoTargets and Therapy 2018, 11:2333-2344
Published Date: 24 April 2018

MicroRNA-150 suppresses triple-negative breast cancer metastasis through targeting HMGA2
Tang W, Xu P, Wang H, Niu Z, Zhu D, Lin Q, Tang L, Ren L
OncoTargets and Therapy 2018, 11:2319-2332
Published Date: 24 April 2018

Risk factors for esophageal fistula in patients with locally advanced esophageal carcinoma receiving chemoradiotherapy

Zhang Y, Li Z, Zhang W, Chen W, Song Y
OncoTargets and Therapy 2018, 11:2311-2317
Published Date: 23 April 2018

Effectiveness of afatinib after ineffectiveness of gefitinib in an advanced lung adenocarcinoma patient with a single EGFR exon 20 S768I mutation: a case report

Duan H, Peng Y, Cui H, Qiu Y, Li Q, Zhang J, Shen W, Sun C, Luo C
OncoTargets and Therapy 2018, 11:2303-2309
Published Date: 23 April 2018

Neuroendocrine tumor of the common bile duct: a case report and review of the literature

Liu Z, Zhang DY, Lu Z, Zhang P, Sun WL, Ma X, Wu H, Wu BQ, Zhou S
OncoTargets and Therapy 2018, 11:2295-2301
Published Date: 23 April 2018

Forodesine in the treatment of relapsed/refractory peripheral T-cell lymphoma: an evidence-based review
Makita S, Maeshima AM, Maruyama D, Izutsu K, Tobinai K
OncoTargets and Therapy 2018, 11:2287-2293
Published Date: 20 April 2018


Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients


Chen Q, Li R, Zhang Z, Deng Q, Li K, Wang H, Yang X, Wu Y
OncoTargets and Therapy 2018, 11:2279-2286
Published Date: 20 April 2018

Modulation of human melanoma cell proliferation and apoptosis by hydatid cyst fluid of Echinococcus granulosus [Corrigendum]
Gao XY, Zhang GH, Huang L
OncoTargets and Therapy 2018, 11:2277-2278
Published Date: 30 April 2018

Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67
Xu J, Guo X, Jing M, Sun T
OncoTargets and Therapy 2018, 11:2269-2275
Published Date: 19 April 2018

Role of DiGeorge syndrome critical region gene 9, a long noncoding RNA, in gastric cancer
Ni C, Yang P, Guo J, Ye M
OncoTargets and Therapy 2018, 11:2259-2267
Published Date: 19 April 2018

Evidence from an updated meta-analysis of the prognostic impacts of postoperative radiotherapy and chemotherapy in patients with anaplastic thyroid carcinoma
Xia Q, Wang W, Xu J, Chen X, Zhong Z, Sun C
OncoTargets and Therapy 2018, 11:2251-2257
Published Date: 19 April 2018


Cardiotoxic effects of the novel approved anti-ErbB2 agents and reverse cardioprotective effects of ranolazine


De Lorenzo C, Paciello R, Riccio G, Rea D, Barbieri A, Coppola C, Maurea N
OncoTargets and Therapy 2018, 11:2241-2250
Published Date: 19 April 2018

microRNA-26a induces a mitochondrial apoptosis mediated by p53 through targeting to inhibit Mcl1 in human hepatocellular carcinoma
Gao X, Zhu Y, Li JH, Wang X, Zhang X, Yi C, Yang X
OncoTargets and Therapy 2018, 11:2227-2239
Published Date: 19 April 2018

EGFR, KRAS, BRAF, PTEN, and PIK3CA mutation in plasma of small cell lung cancer patients
Lu HY, Qin J, Han N, Lei L, Xie F, Li C
OncoTargets and Therapy 2018, 11:2217-2226
Published Date: 20 April 2018

miR-488 inhibits cell growth and metastasis in renal cell carcinoma by targeting HMGN5
Wei X, Yu L, Kong X
OncoTargets and Therapy 2018, 11:2205-2216
Published Date: 18 April 2018
MicroRNA 302b-3p/302c-3p/302d-3p inhibits epithelial–mesenchymal transition and promotes apoptosis in human endometrial carcinoma cells [Erratum]
Li Y, Huo J, Pan X, Wang C, Ma X
OncoTargets and Therapy 2018, 11:2203-2204
Published Date: 17 April 2018

miR-30a suppresses osteosarcoma proliferation and metastasis by downregulating MEF2D expression
Du L, Chen T, Zhao K, Yang D
OncoTargets and Therapy 2018, 11:2195-2202
Published Date: 17 April 2018

The role of Hippo signal pathway in breast cancer metastasis
Wei C, Wang Y, Li X
OncoTargets and Therapy 2018, 11:2185-2193
Published Date: 17 April 2018

Overexpression of HDAC9 is associated with poor prognosis and tumor progression of breast cancer in Chinese females
Huang Y, Jian W, Zhao J, Wang G
OncoTargets and Therapy 2018, 11:2177-2184
Published Date: 17 April 2018

Preoperative apolipoprotein B/apolipoprotein A1 ratio: a novel prognostic factor for gastric cancer
Ma MZ, Yuan SQ, Chen Y, Zhou ZW
OncoTargets and Therapy 2018, 11:2169-2176
Published Date: 13 April 2018

Prognostic and clinicopathological value of SIRT3 expression in various cancers: a systematic review and meta-analysis
Zhou Y, Cheng S, Chen S, Zhao Y
OncoTargets and Therapy 2018, 11:2157-2167
Published Date: 13 April 2018

Multiple treatment modalities for brain metastasis in patients with EGFR-mutant non-small-cell lung cancer
Wang HY, Yu X, Fan Y, Jiang Y
OncoTargets and Therapy 2018, 11:2149-2155
Published Date: 13 April 2018

Profile of apalutamide in the treatment of metastatic castration-resistant prostate cancer: evidence to date
Chong JT, Oh WK, Liaw BC
OncoTargets and Therapy 2018, 11:2141-2147
Published Date: 12 April 2018

Albumin/globulin ratio is negatively correlated with PD-1 and CD25 mRNA levels in breast cancer patients
Liu C, Wang W, Meng XY, Sun B, Cong Y, Liu JN, Wang Q, Liu GX, Wu SK
OncoTargets and Therapy 2018, 11:2131-2139
Published Date: 12 April 2018

Efficacy of pemetrexed-based regimens in advanced non–small cell lung cancer patients with activating epidermal growth factor receptor mutations after tyrosine kinase inhibitor failure: a systematic review
Han BH, Yang LL, Wang X, Yao LD
OncoTargets and Therapy 2018, 11:2121-2129
Published Date: 12 April 2018
Overexpression of high mobility group box 1 contributes to progressive clinicopathological features and poor prognosis of human bladder urothelial carcinoma
Huang CK, Huang ZC, Zhao XK, Wang YH, Zhao HQ, Zhong ZH, Wang L
OncoTargets and Therapy 2018, 11:2111-2120
Published Date: 12 April 2018

Small ubiquitin-like modifier 1 modification of pyruvate kinase M2 promotes aerobic glycolysis and cell proliferation in A549 human lung cancer cells
An S, Huang L, Miao P, Shi L, Shen M, Zhao X, Liu J, Huang G
OncoTargets and Therapy 2018, 11:2097-2109
Published Date: 13 April 2018

Four cycles of adriamycin and cyclophosphamide followed by four cycles of docetaxel (NSABP-B27) with concomitant trastuzumab as neoadjuvant therapy for high-risk, early-stage, HER2-positive breast cancer patients
Abdel-Razeq H, Saadeh SS, Abu-Nasser M, Abdulelah H, Marie L, Salam M, Al-Haj Ali B, Ibrahim M, Rimawi D
OncoTargets and Therapy 2018, 11:2091-2096
Published Date: 11 April 2018

Investigation of LEP and LEPR polymorphisms with the risk of hepatocellular carcinoma: a case–control study in Eastern Chinese Han population
Zhang S, Jiang J, Chen Z, Wang Y, Tang W, Liu C, Liu L, Chen Y
OncoTargets and Therapy 2018, 11:2083-2089
Published Date: 11 April 2018

Expression of pyruvate kinase M2 in human bladder cancer and its correlation with clinical parameters and prognosis
Huang CK, Huang ZC, Bai PM, Luo GC, Zhao XK, Wang XJ
OncoTargets and Therapy 2018, 11:2075-2082
Published Date: 11 April 2018

Role of the NFκB-signaling pathway in cancer
Xia LZ, Tan SM, Zhou YJ, Lin JG, Wang HR, Oyang LD, Tian YT, Liu L, Su M, Wang H, Cao D, Liao QJ
OncoTargets and Therapy 2018, 11:2063-2073
Published Date: 11 April 2018

Combination of SIRT1 and Src overexpression suggests poor prognosis in luminal breast cancer
Tan J, Liu Y, Maimaiti Y, Wang C, Yan Y, Zhou J, Ruan S, Huang T
OncoTargets and Therapy 2018, 11:2051-2061
Published Date: 11 April 2018

IL-21-secreting hUCMSCs combined with miR-200c inhibit tumor growth and metastasis via repression of Wnt/β-catenin signaling and epithelial-mesenchymal transition in epithelial ovarian cancer
Zhang Y, Wang J, Wu D, Li M, Zhao F, Ren M, Cai Y, Dou J
OncoTargets and Therapy 2018, 11:2037-2050
Published Date: 10 April 2018

β-Catenin-driven adrenocortical carcinoma is characterized with immune exclusion
Liu S, Ding G, Zhou Z, Feng C
OncoTargets and Therapy 2018, 11:2029-2036
Published Date: 9 April 2018

Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity
Yao C, Liu B, Qian X, Li L, Cao H, Guo Q, Zhou G
OncoTargets and Therapy 2018, 11:2017-2028
Published Date: 9 April 2018

Butein activates p53 in hepatocellular carcinoma cells via blocking MDM2-mediated ubiquitination
Zhou Y, Wang K, Zhou N, Huang T, Zhu J, Li J
OncoTargets and Therapy 2018, 11:2007-2015
Published Date: 6 April 2018

Role of presurgical targeted molecular therapy in renal cell carcinoma with an inferior vena cava tumor thrombus
Peng C, Gu L, Wang L, Huang Q, Wang B, Guo G, Fan Y, Gao Y, Ma X, Zhang X
OncoTargets and Therapy 2018, 11:1997-2005
Published Date: 6 April 2018

Multiline treatment combining apatinib with toptecan for platinum-resistant recurrent ovarian cancer patients: a report of three cases
Cheng Y, Zhang J, Geng HY, Qin SK, Hua HQ
OncoTargets and Therapy 2018, 11:1989-1995
Published Date: 6 April 2018

Positioning error and expanding margins of planning target volume with kilovoltage cone beam computed tomography for prostate cancer radiotherapy
Wang G, Wang WL, Liu YQ, Dong HM, Hu YX
OncoTargets and Therapy 2018, 11:1981-1988
Published Date: 6 April 2018

Postmastectomy radiotherapy reduces locoregional and disease recurrence in patients with stage II–III triple-negative breast cancer treated with neoadjuvant chemotherapy and mastectomy
Chen XX, Xia F, Luo JR, Ma JL, Yang ZZ, Zhang L, Feng Y, Shao ZM, Yu XL, Guo XM
OncoTargets and Therapy 2018, 11:1973-1980
Published Date: 5 April 2018

Knockdown of fibrous sheath interacting protein 1 expression reduces bladder urothelial carcinoma cell proliferation and induces apoptosis via inhibition of the PI3K/AKT pathway
Sun M, Chen Z, Tan S, Liu C, Zhao W
OncoTargets and Therapy 2018, 11:1961-1971
Published Date: 5 April 2018

Fabrication of ultrasmall WS2 quantum dots-coated periodic mesoporous organosilica nanoparticles for intracellular drug delivery and synergistic chemo-photothermal therapy
Liao W, Zhang L, Zhong Y, Shen Y, Li C, An N
OncoTargets and Therapy 2018, 11:1949-1960
Published Date: 5 April 2018

Inhibition of NIPBL enhances the chemosensitivity of non-small-cell lung cancer cells via the DNA damage response and autophagy pathway
Zheng L, Zhou H, Guo L, Xu X, Zhang S, Xu W, Mao W
OncoTargets and Therapy 2018, 11:1941-1948
Published Date: 5 April 2018

Downregulation of miR-542-3p promotes cancer metastasis through activating TGF-β/Smad signaling in hepatocellular carcinoma
Zhang T, Liu W, Meng W, Zhao H, Yang Q, Gu SJ, Xiao CC, Jia CC, Fu BS
OncoTargets and Therapy 2018, 11:1929-1939
Published Date: 5 April 2018

PET-CT evaluation of the curative effect of crizotinib on malignant myofibroblastoma with rare mutation of ALK R401: a case report and literature review
Yang L, Wu Y, Tang H, Zhao J, Zhao D, Yang S, Wang Q
OncoTargets and Therapy 2018, 11:1921-1927
Published Date: 5 April 2018

miR-495 inhibits proliferation, migration, and invasion and induces apoptosis via inhibiting PBX3 in melanoma cells
Chen G, Xie Y
OncoTargets and Therapy 2018, 11:1909-1920
Published Date: 5 April 2018

Prognostic value of platelet-to-lymphocyte ratio in pancreatic cancer: a comprehensive meta-analysis of 17 cohort studies
Zhou Y, Cheng S, Fathy AH, Qian H, Zhao Y
OncoTargets and Therapy 2018, 11:1899-1908
Published Date: 5 April 2018

99mTc-labeled sodium phytate and stannous chloride injection accurately detects sentinel lymph node in axillary of early stage breast cancer: a randomized, controlled study
Yang S, Bao W, Bai X, Gao C, Zhang B, Jiang Z
OncoTargets and Therapy 2018, 11:1891-1898
Published Date: 4 April 2018

Long-term survival with transarterial chemoembolization and radioembolization in a patient with cancers of unknown primary

Aktas G, Kus T, Metin T, Kervancioglu S, Elboga U
OncoTargets and Therapy 2018, 11:1885-1889
Published Date: 4 April 2018

Antiangiogenic effects of AA-PMe on HUVECs in vitro and zebrafish in vivo
Jing Y, Wang G, Xiao Q, Zhou Y, Wei Y, Gong Z
OncoTargets and Therapy 2018, 11:1871-1884
Published Date: 4 April 2018

Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis
Zhou L, Du Y, Kong L, Zhang X, Chen Q
OncoTargets and Therapy 2018, 11:1861-1869
Published Date: 4 April 2018

Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor
Wang G, Li L, Liu B, Han X, Wang CH, Wang JW
OncoTargets and Therapy 2018, 11:1849-1859
Published Date: 4 April 2018

D-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer
Yu X, Lin H, Wang Y, Lv W, Zhang S, Qian Y, Deng X, Feng N, Yu H, Qian B
OncoTargets and Therapy 2018, 11:1833-1847
Published Date: 4 April 2018

Clinicopathological characteristics and prognostic value of the cancer stem cell marker ALDH1 in ovarian cancer: a meta-analysis
Zhao W, Zang C, Zhang T, Li J, Liu R, Feng F, Lv Q, Zheng L, Tian J, Sun C
OncoTargets and Therapy 2018, 11:1821-1831
Published Date: 3 April 2018

Rare malignant insulinoma with multiple liver metastases derived from ectopic pancreas: 3-year follow-up and literature review
Liu Q, Duan JH, Zheng YM, Luo J, Cai XP, Tan HY
OncoTargets and Therapy 2018, 11:1813-1819
Published Date: 3 April 2018

Association between WWOX and the risk of malignant tumor, especially among Asians: evidence from a meta-analysis
Yuan H, Wu Y, Zhang J, Shi G, Liu D, He Y, Lu Z, Wu P, Jiang K, Miao Y
OncoTargets and Therapy 2018, 11:1801-1811
Published Date: 3 April 2018

Prognostic value of increased integrin-beta 1 expression in solid cancers: a meta-analysis
Sun Q, Zhou C, Ma R, Guo Q, Huang H, Hao J, Liu H, Shi R, Liu B
OncoTargets and Therapy 2018, 11:1787-1799
Published Date: 29 March 2018

Synergistic antitumor effects of tanshinone IIA and sorafenib or its derivative SC-1 in hepatocellular carcinoma cells
Chiu CM, Huang SY, Chang SF, Liao KF, Chiu SC
OncoTargets and Therapy 2018, 11:1777-1785
Published Date: 29 March 2018

Metformin inhibits proliferation and cytotoxicity and induces apoptosis via AMPK pathway in CD19-chimeric antigen receptor-modified T cells
Mu Q, Jiang M, Zhang Y, Wu F, Li H, Zhang W, Wang F, Liu J, Li L, Wang D, Wang W, Li S, Song H, Tang D
OncoTargets and Therapy 2018, 11:1767-1776
Published Date: 3 April 2018

miR-206 regulates 5-FU resistance by targeting Bcl-2 in colon cancer cells
Meng X, Fu R
OncoTargets and Therapy 2018, 11:1757-1765
Published Date: 29 March 2018

Antibody-sandwich ELISA analysis of a novel blood biomarker of CST4 in gastrointestinal cancers
Dou YL, Lv YL, Zhou XJ, He LF, Liu LH, Li PF, Sun YL, Wang MH, Gao MJ, Wang C
OncoTargets and Therapy 2018, 11:1743-1756
Published Date: 28 March 2018

MiR-152 functioning as a tumor suppressor that interacts with DNMT1 in nasopharyngeal carcinoma
Lu Z, Du M, Qian L, Zhang N, Gu J, Ding K, Wu J, Zhu H, He X, Yin L
OncoTargets and Therapy 2018, 11:1733-1741
Published Date: 27 March 2018

miR-1269 promotes cell survival and proliferation by targeting tp53 and caspase-9 in lung cancer
Bao M, Song YJ, Xia JJ, Li PL, Liu Q, Wan ZR
OncoTargets and Therapy 2018, 11:1721-1732
Published Date: 26 March 2018

KIF18B promotes tumor progression through activating the Wnt/β-catenin pathway in cervical cancer
Wu Y, Wang A, Zhu B, Huang J, Lu E, Xu H, Xia W, Dong G, Jiang F, Xu L
OncoTargets and Therapy 2018, 11:1707-1720
Published Date: 28 March 2018

Upregulated VEGFA and DLL4 act as potential prognostic genes for clear cell renal cell carcinoma
Wang X, Zhang J, Wang Y, Tu M, Wang Y, Shi G
OncoTargets and Therapy 2018, 11:1697-1706
Published Date: 26 March 2018

Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer
Yuan W, Xie S, Wang M, Pan S, Huang X, Xiong M, Xiao R, Xiong J, Zhang Q, Shao L
OncoTargets and Therapy 2018, 11:1683-1695
Published Date: 23 March 2018

MiR-216b suppresses colorectal cancer proliferation, migration, and invasion by targeting SRPK1
Yao YF, Li QR, Wang H
OncoTargets and Therapy 2018, 11:1671-1681
Published Date: 23 March 2018

The incidence of postoperative radiotherapy-induced acute dermatitis in breast cancer and its influencing factors for Chinese women
Ding J, Guo Y, Li Q, Chen J, Hu P, Liu Q, Cao Y, Wu J
OncoTargets and Therapy 2018, 11:1665-1670
Published Date: 23 March 2018

Biomarker expression in rectal cancer tissue before and after neoadjuvant therapy
Boogerd LS, van der Valk MJM, Boonstra MC, Prevoo HA, Hilling DE, van de Velde CJ, Sier CF, Fariña Sarasqueta A, Vahrmeijer AL
OncoTargets and Therapy 2018, 11:1655-1664
Published Date: 23 March 2018

miR-342-3p suppresses hepatocellular carcinoma proliferation through inhibition of IGF-1R-mediated Warburg effect
Liu W, Kang L, Han J, Wang Y, Shen C, Yan Z, Tai Y, Zhao C
OncoTargets and Therapy 2018, 11:1643-1653
Published Date: 23 March 2018

Effects of isoliquiritigenin on ovarian cancer cells
Li N, Yang L, Deng XN, Sun YN
OncoTargets and Therapy 2018, 11:1633-1642
Published Date: 22 March 2018


Open adrenalectomy versus laparoscopic adrenalectomy for adrenocortical carcinoma: a retrospective comparative study on short-term oncologic prognosis
Zheng G, Li H, Deng J, Zhang X, Wu X
OncoTargets and Therapy 2018, 11:1625-1632
Published Date: 21 March 2018

Tooth loss and risk of colorectal cancer: a dose–response meta-analysis of prospective cohort studies
Ma P, Dai S, Jin C, Yao Y, Zou C
OncoTargets and Therapy 2018, 11:1617-1623
Published Date: 21 March 2018

Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells
Chen YC, Chen IS, Huang GJ, Kang CH, Wang KC, Tsao MJ, Pan HW
OncoTargets and Therapy 2018, 11:1601-1616
Published Date: 21 March 2018

Lung squamous cell carcinoma associated with hypoparathyroidism with sensorineural deafness and renal dysplasia syndrome: a case report

Kojima M, Nagano T, Nakata K, Hara S, Katsurada N, Yamamoto M, Tachihara M, Kamiryo H, Kobayashi K, Usui T, Nishimura Y
OncoTargets and Therapy 2018, 11:1595-1599
Published Date: 20 March 2018
Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis
Sun L, Yang S, Chi G, Jin X
OncoTargets and Therapy 2018, 11:1583-1593
Published Date: 20 March 2018

High expression of COL10A1 is associated with poor prognosis in colorectal cancer
Huang H, Li T, Ye G, Zhao L, Zhang Z, Mo D, Wang Y, Zhang C, Deng H, Li G, Liu H
OncoTargets and Therapy 2018, 11:1571-1581
Published Date: 20 March 2018

Overexpression of HHLA2, a member of the B7 family, is associated with worse survival in human colorectal carcinoma
Zhu Z, Dong W
OncoTargets and Therapy 2018, 11:1563-1570
Published Date: 20 March 2018

Forecast of actin-binding proteins as the oncotarget in osteosarcoma – a review of mechanism, diagnosis and therapy
Fu Y, Yu W, Cai H, Lu A
OncoTargets and Therapy 2018, 11:1553-1561
Published Date: 20 March 2018

Novel long noncoding RNA GACAT3 promotes colorectal cancer cell proliferation, invasion, and migration through miR-149
Zhou W, Wang L, Miao Y, Xing R
OncoTargets and Therapy 2018, 11:1543-1552
Published Date: 19 March 2018

Functional miRNAs in breast cancer drug resistance
Hu WZ, Tan CL, He YJ, Zhang GQ, Xu Y, Tang JH
OncoTargets and Therapy 2018, 11:1529-1541
Published Date: 19 March 2018

Primary mucinous carcinoma of thyroid gland with prominent signet-ring-cell differentiation: a case report and review of the literature
Wang J, Guli QR, Ming XC, Zhou HT, Cui YJ, Jiang YF, Zhang D, Liu Y
OncoTargets and Therapy 2018, 11:1521-1528
Published Date: 16 March 2018

STK39 blockage by RNA interference inhibits the proliferation and induces the apoptosis of renal cell carcinoma
Zhao Q, Zhu YJ, Liu L, Wang H, Jiang S, Hu X, Guo J
OncoTargets and Therapy 2018, 11:1511-1519
Published Date: 16 March 2018

miR-622 suppresses tumor formation by directly targeting VEGFA in papillary thyroid carcinoma
Wang R, Ma Q, Ji L, Yao Y, Ma M, Wen Q
OncoTargets and Therapy 2018, 11:1501-1509
Published Date: 16 March 2018

Upregulated long non-coding RNAs demonstrate promising efficacy for breast cancer detection: a meta-analysis
Yu G, Zhang W, Zhu L, Xia L
OncoTargets and Therapy 2018, 11:1491-1499
Published Date: 16 March 2018

Midazolam activates caspase, MAPKs and endoplasmic reticulum stress pathways, and inhibits cell cycle and Akt pathway, to induce apoptosis in TM3 mouse Leydig progenitor cells
Kang FC, Wang SC, Chang MM, Pan BS, Wong KL, Cheng KS, So EC, Huang BM
OncoTargets and Therapy 2018, 11:1475-1490
Published Date: 15 March 2018

Identification of differentially expressed genes and signaling pathways in ovarian cancer by integrated bioinformatics analysis
Yang X, Zhu S, Li L, Zhang L, Xian S, Wang Y, Cheng Y
OncoTargets and Therapy 2018, 11:1457-1474
Published Date: 15 March 2018

Modulation of human melanoma cell proliferation and apoptosis by hydatid cyst fluid of Echinococcus granulosus
Gao X, Zhang G, Huang L
OncoTargets and Therapy 2018, 11:1447-1456
Published Date: 15 March 2018

Measurement of serum PODXL concentration for detection of pancreatic cancer
Taniuchi K, Tsuboi M, Sakaguchi M, Saibara T
OncoTargets and Therapy 2018, 11:1433-1445
Published Date: 15 March 2018

Peripheral inflammation/immune indicators of chemosensitivity and prognosis in breast cancer patients treated with neoadjuvant chemotherapy
Qian Y, Tao J, Li X, Chen H, Lu Q, Yang J, Pan H, Wang C, Zhou W, Liu X
OncoTargets and Therapy 2018, 11:1423-1432
Published Date: 15 March 2018

Upregulation of FOXP1 is a new independent unfavorable prognosticator and a specific predictor of lymphatic dissemination in cutaneous melanoma patients
Donizy P, Pagacz K, Marczuk J, Fendler W, Maciejczyk A, Halon A, Matkowski R
OncoTargets and Therapy 2018, 11:1413-1422
Published Date: 14 March 2018

Long non-coding RNA FENDRR inhibits cell proliferation and is associated with good prognosis in breast cancer
Li Y, Zhang W, Liu P, Xu Y, Tang L, Chen W, Guan X
OncoTargets and Therapy 2018, 11:1403-1412
Published Date: 14 March 2018

Fast hemostasis: a win-win strategy for ultrasound and microwave ablation
Guo J, Tian G, Zhao Q, Jiang T
OncoTargets and Therapy 2018, 11:1395-1402
Published Date: 13 March 2018

Rhein inhibits malignant phenotypes of human renal cell carcinoma by impacting on MAPK/NF-κB signaling pathways
Ma YL, Chen F, Shi J
OncoTargets and Therapy 2018, 11:1385-1394
Published Date: 14 March 2018

Reliability of using circulating tumor cells for detecting epidermal growth factor receptor mutation status in advanced non-small-cell lung cancer patients: a meta-analysis and systematic review
Hu F, Mao XW, Zhang YJ, Zheng XX, Gu P, Wang HM, Zhang XY
OncoTargets and Therapy 2018, 11:1373-1384
Published Date: 14 March 2018

Evaluation of biologically active substances promoting the development of or protecting against endometrial cancer
Cymbaluk-Płoska A, Chudecka-Głaz A, Jagodzińska A, Pius-Sadowska E, Sompolska-Rzechuła A, Machaliński B, Menkiszak J
OncoTargets and Therapy 2018, 11:1363-1372
Published Date: 13 March 2018

Clinicopathological features and prognosis in elderly gastric cancer patients: a retrospective cohort study
Xu G, Feng F, Liu S, Wang F, Zheng G, Wang Q, Cai L, Guo M, Lian X, Zhang H
OncoTargets and Therapy 2018, 11:1353-1362
Published Date: 12 March 2018

IL13Rα2 siRNA inhibited cell proliferation, induced cell apoptosis, and suppressed cell invasion in papillary thyroid carcinoma cells
Gu MJ
OncoTargets and Therapy 2018, 11:1345-1352
Published Date: 9 March 2018

SPP1 promotes ovarian cancer progression via Integrin β1/FAK/Akt signaling pathway
Zeng B, Zhou M, Wu H, Xiong Z
OncoTargets and Therapy 2018, 11:1333-1343
Published Date: 12 March 2018

CREB promotes laryngeal cancer cell migration via MYCT1/NAT10 axis
Zhang ZX, Zhang WN, Sun YY, Li YH, Xu ZM, Fu WN
OncoTargets and Therapy 2018, 11:1323-1331
Published Date: 8 March 2018

Clinicopathological characteristics and prognosis of adult ovarian granulosa cell tumor: a single-institution experience in China
Wang D, Xiang Y, Wu M, Shen K, Yang J, Huang H, Ren T
OncoTargets and Therapy 2018, 11:1315-1322
Published Date: 7 March 2018

Prognostic significance of preoperative IKBKE expression in esophageal squamous cell carcinoma
Yang WJ, Qu Y, Tan BX, Jia YB, Wang NN, Hu P, Wang JB
OncoTargets and Therapy 2018, 11:1305-1314
Published Date: 7 March 2018

The clinicopathological and prognostic value of HSP27 in hepatocellular carcinoma: a systematic review and meta-analysis
Liang CJ, Xu YC, Ge H, Li GM, Wu JX
OncoTargets and Therapy 2018, 11:1293-1303
Published Date: 7 March 2018

Overexpression of c-kit(CD117), relevant with microvessel density, is an independent survival prognostic factor for patients with HBV-related hepatocellular carcinoma
Yan W, Zhu Z, Pan F, Huang A, Dai G
OncoTargets and Therapy 2018, 11:1285-1292
Published Date: 7 March 2018

MicroRNA 302b-3p/302c-3p/302d-3p inhibits epithelial–mesenchymal transition and promotes apoptosis in human endometrial carcinoma cells
Li Y, Huo J, Pan X, Wang C, Ma X
OncoTargets and Therapy 2018, 11:1275-1284
Published Date: 6 March 2018

Vascular endothelial growth factor suppresses dendritic cells function of human prostate cancer
Bai WK, Zhang W, Hu B
OncoTargets and Therapy 2018, 11:1267-1274
Published Date: 6 March 2018
Decreased expression of LKB1 predicts poor prognosis in pancreatic neuroendocrine tumor patients undergoing curative resection
Li D, Zhou Y, Liu Y, Lin Y, Yu M, Lu X, Huang B, Sun Z, Jian Z, Hou B
OncoTargets and Therapy 2018, 11:1259-1265
Published Date: 6 March 2018

Icotinib hydrochloride enhances chemo- and radiosensitivity by inhibiting EGFR signaling and attenuating RAD51 expression and function in Hela S3 cells
Wang X, Gu Y, Liu H, Shi L, Sun X
OncoTargets and Therapy 2018, 11:1245-1258
Published Date: 5 March 2018
Clinical value of Xenopus kinesin-like protein 2 as a prognostic marker in patients with digestive system cancers: a systematic review and meta-analysis
Wang G, Wang Q, Li Z, Liu C, He X
OncoTargets and Therapy 2018, 11:1229-1243
Published Date: 5 March 2018


A national, multicenter, non-interventional, observational study on treatment patterns in patients with metastatic renal cell carcinoma in Turkey – NOTES study


Yalcin Ş, Yildiz R, Dane F, Karaoğlu A, Öksüzoğlu B, Özyilkan Ö, Sevinç A, Özdemir F, Turna H, Uslu R, Ulay E
OncoTargets and Therapy 2018, 11:1223-1228
Published Date: 5 March 2018

Leukemia-related protein 16 (LRP16) promotes tumor growth and metastasis in pancreatic cancer
Mo Z, Hu MG, Yu F, Shao LJ, Fan KX, Jiao SC
OncoTargets and Therapy 2018, 11:1215-1222
Published Date: 5 March 2018

Clinicopathological significance and prognostic role of p-STAT3 in patients with hepatocellular carcinoma
Liang CJ, Xu Y, Ge H, Li G, Wu J
OncoTargets and Therapy 2018, 11:1203-1214
Published Date: 5 March 2018

Impact of diabetes mellitus on the risk and survival of nasopharyngeal carcinoma: a meta-analysis
Guo G, Fu M, Wei S, Chen R
OncoTargets and Therapy 2018, 11:1193-1201
Published Date: 2 March 2018

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma
Wang R, Deng D, Shao N, Xu Y, Xue L, Peng Y, Liu Y, Zhi F
OncoTargets and Therapy 2018, 11:1183-1192
Published Date: 2 March 2018

Hepatitis C virus core impacts expression of miR122 and miR204 involved in carcinogenic progression via regulation of TGFBRAP1 and HOTTIP expression
Wang X, Peng J, Wang J, Li M, Wu D, Wu S, Liao J, Dou J
OncoTargets and Therapy 2018, 11:1173-1182
Published Date: 2 March 2018

SIRT1 overexpression protects non-small cell lung cancer cells against osteopontin-induced epithelial-mesenchymal transition by suppressing NF-κB signaling
Li X, Jiang Z, Li XM, Zhang X
OncoTargets and Therapy 2018, 11:1157-1171
Published Date: 2 March 2018

Cisplatin concurrent chemoradiotherapy vs adjuvant radiation in stage IB/IIA cervical cancer with intermediate risk factors, treated with radical surgery: a retrospective study
Sun H, Tang Q, Chen J, Lv X, Tu Y, Yan D
OncoTargets and Therapy 2018, 11:1149-1155
Published Date: 6 March 2018

Effects of propofol-based total intravenous anesthesia on gastric cancer: a retrospective study
Zheng XY, Wang Y, Dong LL, Zhao S, Wang LP, Chen H, Xu Y, Wang GN
OncoTargets and Therapy 2018, 11:1141-1148
Published Date: 1 March 2018

rs11614913 polymorphism in miRNA-196a2 and cancer risk: an updated meta-analysis
Liu Y, He A, Liu B, Zhong Y, Liao X, Yang J, Chen J, Wu J, Mei H
OncoTargets and Therapy 2018, 11:1121-1139
Published Date: 1 March 2018

Response to crizotinib in a non-small-cell lung cancer patient harboring an EML4-ALK fusion with an atypical LTBP1 insertion
Aguado C, Gil MDLL, Yeste Z, Giménez-Capitán A, Teixidó C, Karachaliou N, Viteri S, Rosell R, Molina-Vila MA
OncoTargets and Therapy 2018, 11:1117-1120
Published Date: 1 March 2018

The efficacy and safety of alectinib in the treatment of ALK+ NSCLC: a systematic review and meta-analysis
Fan JS, Xia ZF, Zhang XL, Chen YQ, Qian RL, Liu SH, You DM, Zhang J, Luo P
OncoTargets and Therapy 2018, 11:1105-1115
Published Date: 1 March 2018

TSPAN12 is overexpressed in NSCLC via p53 inhibition and promotes NSCLC cell growth in vitro and in vivo
Hu Z, Hou D, Wang X, You Z, Cao X
OncoTargets and Therapy 2018, 11:1095-1103
Published Date: 1 March 2018

Comparison between multi-slice spiral CT and magnetic resonance imaging in the diagnosis of peritoneal metastasis in primary ovarian carcinoma

Guo HL, He L, Zhu YC, Wu K, Yuan F
OncoTargets and Therapy 2018, 11:1087-1094
Published Date: 28 February 2018

Association of doublecortin-like kinase 1 with tumor aggressiveness and poor biochemical recurrence-free survival in prostate cancer
Jiang DG, Xiao CT, Xian TZ, Wang LT, Mao YH, Zhang JF, Pang J
OncoTargets and Therapy 2018, 11:1077-1086
Published Date: 28 February 2018

Forkhead box K2 inhibits the proliferation, migration, and invasion of human glioma cells and predicts a favorable prognosis
Wang B, Zhang XB, Wang W, Zhu ZZ, Tang F, Wang D, Liu X, Zhuang H, Yan XL
OncoTargets and Therapy 2018, 11:1067-1075
Published Date: 27 February 2018

Genetic association between HER2 and ESR2 polymorphisms and ovarian cancer: a meta-analysis
Tang L, Li J, Bao M, Xiang J, Chen Y, Wang Y
OncoTargets and Therapy 2018, 11:1055-1066
Published Date: 1 March 2018

CXCR3 is a prognostic marker and a potential target for patients with solid tumors: a meta-analysis
Zhang Y, Xu L, Peng M
OncoTargets and Therapy 2018, 11:1045-1054
Published Date: 27 February 2018

Clinicopathologic characteristics and prognosis of proximal and distal gastric cancer
Yu X, Hu F, Li C, Yao Q, Zhang H, Xue Y
OncoTargets and Therapy 2018, 11:1037-1044
Published Date: 27 February 2018

Reversine, a substituted purine, exerts an inhibitive effect on human renal carcinoma cells via induction of cell apoptosis and polyploidy
Cheng L, Wang H, Guo KC, Wang ZC, Zhang ZY, Shen C, Chen L, Lin J
OncoTargets and Therapy 2018, 11:1025-1035
Published Date: 26 February 2018

Prognostic value of circulating tumor cells detected with the CellSearch System in patients with gastric cancer: evidence from a meta-analysis
Yang C, Zou K, Yuan Z, Guo T, Xiong B
OncoTargets and Therapy 2018, 11:1013-1023
Published Date: 26 February 2018
How many ELNs are optimal for breast cancer patients with more than three PLNs who underwent MRM? A large population-based study
Wang X, Ji C, Chi H, Wang H
OncoTargets and Therapy 2018, 11:1005-1011
Published Date: 26 February 2018

Prognostic significance of Epstein–Barr virus DNA in NK/T-cell lymphoma: a meta-analysis
Fei Q, Tian X, Wu J, Zhu H, Wang Y, Peng F, Zhang W, Yin L, He X
OncoTargets and Therapy 2018, 11:997-1004
Published Date: 26 February 2018

Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway
Yang C, Hou A, Yu C, Dai L, Wang W, Zhang K, Shao H, Ma J, Xu W
OncoTargets and Therapy 2018, 11:983-996
Published Date: 26 February 2018

Role of palliative resection of the primary pancreatic neuroendocrine tumor in patients with unresectable metastatic liver disease: a systematic review and meta-analysis
Zhou B, Zhan C, Ding Y, Yan S, Zheng S
OncoTargets and Therapy 2018, 11:975-982
Published Date: 23 February 2018

Prognostic significance of mucinous component in gastric adenocarcinoma after radical D2 gastrectomy
Cai L, Li Y, Yang X, Lian X, Guo M, Xiao S, Wang W, Zhang H
OncoTargets and Therapy 2018, 11:967-973
Published Date: 23 February 2018

Prognostic utility of baseline neutrophil-to-lymphocyte ratio in patients receiving immune checkpoint inhibitors: a review and meta-analysis
Sacdalan DB, Lucero JA, Sacdalan DL
OncoTargets and Therapy 2018, 11:955-965
Published Date: 23 February 2018

Role of ubenimex as an anticancer drug and its synergistic effect with Akt inhibitor in human A375 and A2058 cells
Wang X, Liu Y, Wu R, Guo F, Zhang L, Cui M, Wu X, Zhang Y, Liu W
OncoTargets and Therapy 2018, 11:943-953
Published Date: 22 February 2018

Characterization of luteinizing hormone-releasing hormone receptor type I (LH-RH-I) as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines
Sipos E, Dobos N, Rozsa D, Fodor K, Olah G, Szabo Z, Szekvolgyi L, Schally AV, Halmos G
OncoTargets and Therapy 2018, 11:933-941
Published Date: 22 February 2018

The investigation for potential modifier genes in patients with neurofibromatosis type 1 based on next-generation sequencing

Yang F, Xu S, Liu RW, Shi T, Li XF, Li XB, Chen G, Liu HY, Zhou QH, Chen J
OncoTargets and Therapy 2018, 11:919-932
Published Date: 21 February 2018

Low levels of tumor suppressor candidate 3 predict poor prognosis of patients with hepatocellular carcinoma
Sheng XR, Xing SG, Wang RD, Chen K, Jia WD
OncoTargets and Therapy 2018, 11:909-917
Published Date: 21 February 2018

Postoperative hepatic arterial infusion chemotherapy improved survival of pancreatic cancer after radical pancreatectomy: a retrospective study
Wang Y, Xu Y, Zheng Y, Bao Y, Wang P
OncoTargets and Therapy 2018, 11:903-907
Published Date: 21 February 2018

CDCA5 regulates proliferation in hepatocellular carcinoma and has potential as a negative prognostic marker
Shen Z, Yu X, Zheng Y, Lai X, Li J, Hong Y, Zhang H, Chen C, Su Z, Guo R
OncoTargets and Therapy 2018, 11:891-901
Published Date: 20 February 2018


Successful treatment of metastatic colorectal cancer with apatinib: report of two cases and literature review


Bi MH, Yang JR, Wang YP, Zhang HR, Gao ZY, Zhou HR, Shi MH
OncoTargets and Therapy 2018, 11:883-890
Published Date: 19 February 2018

Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy
Chen X, Tong H, Chen Y, Chen C, Ye J, Mo Q, Zhao G, Hong G, Zheng C, Lu Z
OncoTargets and Therapy 2018, 11:867-881
Published Date: 19 February 2018

Effects of four single nucleotide polymorphisms of EZH2 on cancer risk: a systematic review and meta-analysis
Ling Z, You Z, Hu L, Zhang L, Wang Y, Zhang M, Zhang G, Chen S, Xu B, Chen M
OncoTargets and Therapy 2018, 11:851-865
Published Date: 16 February 2018

Interleukin-33 enhanced the migration and invasiveness of human lung cancer cells
Yang Z, Gao X, Wang J, Xu L, Zheng Y, Xu Y
OncoTargets and Therapy 2018, 11:843-849
Published Date: 16 February 2018

Developments in the management of advanced soft-tissue sarcoma – olaratumab in context
Moroncini G, Maccaroni E, Fiordoliva I, Pellei C, Gabrielli A, Berardi R
OncoTargets and Therapy 2018, 11:833-842
Published Date: 16 February 2018

MiR-1180-5p regulates apoptosis of Wilms’ tumor by targeting p73
Jiang X, Li H
OncoTargets and Therapy 2018, 11:823-831
Published Date: 16 February 2018

Knockdown of KLK11 reverses oxaliplatin resistance by inhibiting proliferation and activating apoptosis via suppressing the PI3K/AKT signal pathway in colorectal cancer cell
Zhang Y, Xu Z, Sun Y, Chi P, Lu X
OncoTargets and Therapy 2018, 11:809-821
Published Date: 16 February 2018

Clinical significance of quantitative HER2 gene amplification as related to its predictive value in breast cancer patients in neoadjuvant setting
Wu Z, Xu S, Zhou L, Yin W, Lin Y, Du Y, Wang Y, Jiang Y, Yin K, Zhang J, Lu J
OncoTargets and Therapy 2018, 11:801-808
Published Date: 15 February 2018
The association between HOTAIR polymorphisms and cancer susceptibility: an updated systemic review and meta-analysis
Min L, Mu X, Tong A, Qian Y, Ling C, Yi T, Zhao X
OncoTargets and Therapy 2018, 11:791-800
Published Date: 14 February 2018

ISL1 is upregulated in breast cancer and promotes cell proliferation, invasion, and angiogenesis
Li L, Sun F, Chen X, Zhang M
OncoTargets and Therapy 2018, 11:781-789
Published Date: 14 February 2018

Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial–mesenchymal transition via regulating the PI3K/AKT/mTOR pathway
Huang Y, Wu S, Zhang Y, Wang L, Guo Y
OncoTargets and Therapy 2018, 11:769-779
Published Date: 12 February 2018

Raptor mediates the antiproliferation of cardamonin by mTORC1 inhibition in SKOV3 cells
Shi D, Zhu Y, Niu P, Zhou J, Chen H
OncoTargets and Therapy 2018, 11:757-767
Published Date: 9 February 2018

Molecular features of giant-cell carcinoma of the lung: a case report and literature review
Li X, Zhang ZH, Liu JH, Wang D, Wei S, Chen J
OncoTargets and Therapy 2018, 11:751-756
Published Date: 9 February 2018

Expression of Nemo-like kinase in cervical squamous cell carcinoma: a clinicopathological study
Yang W, Gu L, Yang C, Liu T
OncoTargets and Therapy 2018, 11:743-749
Published Date: 8 February 2018

Prognostic significance of epidermal growth factor receptor expression in glioma patients
Li JH, Liang RF, Song C, Xiang YF, Liu YH
OncoTargets and Therapy 2018, 11:731-742
Published Date: 7 February 2018

Efficacy and safety of COX-2 inhibitors for advanced non-small-cell lung cancer with chemotherapy: a meta-analysis
Dai P, Li J, Ma XP, Huang J, Meng JJ, Gong P
OncoTargets and Therapy 2018, 11:721-730
Published Date: 5 February 2018

Use of phosphodiesterase type 5 inhibitors and risk of melanoma: a meta-analysis of observational studies
Han X, Han Y, Zheng Y, Sun Q, Ma T, Dai L, Zhang J, Xu L
OncoTargets and Therapy 2018, 11:711-720
Published Date: 5 February 2018

Association between IL-17A G197A polymorphism and gastric cancer risk: an updated meta-analysis based on 6,624 cases and 7,631 controls
Hu L, Kong F, Pan Y
OncoTargets and Therapy 2018, 11:703-710
Published Date: 5 February 2018

Overexpression of Zwint predicts poor prognosis and promotes the proliferation of hepatocellular carcinoma by regulating cell-cycle-related proteins
Ying H, Xu Z, Chen M, Zhou S, Liang X, Cai X
OncoTargets and Therapy 2018, 11:689-702
Published Date: 2 February 2018
PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells [Corrigendum]
Guo L, Huang S, Wang X
OncoTargets and Therapy 2018, 11:687-688
Published Date: 2 February 2018

Effects of core needle biopsy and subsequent neoadjuvant chemotherapy on molecular alterations and outcome in breast cancer
Xie L, Li X, Wang Q, Zhou J, Shen J, Luo L, Lu Y, Wang L
OncoTargets and Therapy 2018, 11:677-685
Published Date: 1 February 2018

Associations between ABCG2 gene polymorphisms and gefitinib toxicity in non-small cell lung cancer: a meta-analysis
Tang LN, Zhang CL, He HR, Pan ZY, Fan D, He YL, You HS, Li YJ
OncoTargets and Therapy 2018, 11:665-675
Published Date: 1 February 2018

Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance
Li J, Ye D, Wang L, Peng Y, Li Q, Deng H, Zhou C
OncoTargets and Therapy 2018, 11:651-663
Published Date: 1 February 2018

LincRNA-ROR promotes metastasis and invasion of esophageal squamous cell carcinoma by regulating miR-145/FSCN1
Shang M, Wang X, Zhang Y, Gao Z, Wang T, Liu R
OncoTargets and Therapy 2018, 11:639-649
Published Date: 31 January 2018

The lncRNA PCAT1 is correlated with poor prognosis and promotes cell proliferation, invasion, migration and EMT in osteosarcoma
Zhang X, Zhang Y, Mao Y, Ma X
OncoTargets and Therapy 2018, 11:629-638
Published Date: 31 January 2018

The application of a three-dimensional visualized seed planning and navigation system in 125I seed implantation for pancreatic cancer
Hu YY, Qi EP, Liu FY, Lu YH, Tan SL, Sun Y, Han ZY, Liang P, Yu XL
OncoTargets and Therapy 2018, 11:619-627
Published Date: 31 January 2018

Identification of genomic expression differences between right-sided and left-sided colon cancer based on bioinformatics analysis
Peng Q, Lin K, Chang T, Zou L, Xing P, Shen Y, Zhu Y
OncoTargets and Therapy 2018, 11:609-618
Published Date: 31 January 2018

ALDH1A2 suppresses epithelial ovarian cancer cell proliferation and migration by downregulating STAT3
Wang Y, Shao F, Chen L
OncoTargets and Therapy 2018, 11:599-608
Published Date: 31 January 2018

Application of serum microRNA-9-5p, 21-5p, and 223-3p combined with tumor markers in the diagnosis of non-small-cell lung cancer in Yunnan in southwestern China
Yang YL, Chen K, Zhou YC, Hu ZX, Chen S, Huang YC
OncoTargets and Therapy 2018, 11:587-597
Published Date: 30 January 2018

miR-106b-5p promotes stem cell-like properties of hepatocellular carcinoma cells by targeting PTEN via PI3K/Akt pathway
Shi DM, Bian XY, Qin CD, Wu WZ
OncoTargets and Therapy 2018, 11:571-585
Published Date: 26 January 2018

A non-synonymous polymorphism in NBS1 is associated with progression from chronic hepatitis B virus infection to hepatocellular carcinoma in a Chinese population
Zhen YN, Xiao RX, Chen X, Yuan CJ, Sun YL, Li J
OncoTargets and Therapy 2018, 11:563-569
Published Date: 26 January 2018

Clinical manifestations of pulmonary mucosa-associated lymphoid tissue lymphoma: single-center experience with 18 patients
Zhao S, Zhang L, Gu Z, Zhu C, Fang S, Yang N, Wang F, Guan L, Luo L, Gao C
OncoTargets and Therapy 2018, 11:555-561
Published Date: 24 January 2018

Quantification of heart, pericardium, and left ventricular myocardium movements during the cardiac cycle for thoracic tumor radiotherapy
Tong Y, Yin Y, Lu J, Liu T, Chen J, Cheng P, Gong G
OncoTargets and Therapy 2018, 11:547-554
Published Date: 24 January 2018

Nomogram for predicting survival in patients with pancreatic cancer
Song W, Miao DL, Chen L
OncoTargets and Therapy 2018, 11:539-545
Published Date: 24 January 2018


Clinical efficacy and safety of afatinib in the treatment of non-small-cell lung cancer in Chinese patients


Wang LY, Cui JJ, Guo AX, Yin JY
OncoTargets and Therapy 2018, 11:529-538
Published Date: 24 January 2018

The role of bevacizumab in targeted vascular endothelial growth factor therapy for epithelial ovarian cancer: an updated systematic review and meta-analysis
Ruan GY, Ye LX, Liu GF, An J, Sehouli J, Sun PM
OncoTargets and Therapy 2018, 11:521-528
Published Date: 23 January 2018

The prognostic role of Gas6/Axl axis in solid malignancies: a meta-analysis and literature review
Zhang S, Xu XS, Yang JX, Guo JH, Chao TF, Tong YX
OncoTargets and Therapy 2018, 11:509-519
Published Date: 23 January 2018

Prognostic role of neutrophil–lymphocyte ratio in multiple myeloma: a dose–response meta-analysis
Mu S, Ai L, Fan F, Sun C, Hu Y
OncoTargets and Therapy 2018, 11:499-507
Published Date: 23 January 2018

ROS-dependent Bax/Bcl2 and caspase 3 pathway-mediated apoptosis induced by zineb in human keratinocyte cells
Ali D, Tripathi A, Al Ali H, Shahi Y, Mishra KK, Alarifi S, Alkahtane AA, Manohardas S
OncoTargets and Therapy 2018, 11:489-497
Published Date: 23 January 2018

Synovial sarcoma of the maxillary sinus: an extremely rare case with excellent response to chemotherapy

Saito S, Ozawa H, Ikari Y, Nakahara N, Ito F, Sekimizu M, Fukada J, Kameyama K, Ogawa K
OncoTargets and Therapy 2018, 11:483-488
Published Date: 23 January 2018

Homeobox C10 knockdown suppresses cell proliferation and promotes cell apoptosis in osteosarcoma cells through regulating caspase 3
Xie X, Xiao Y, Huang X
OncoTargets and Therapy 2018, 11:473-482
Published Date: 22 January 2018

Subsequent anti-VEGF therapy after first-line anti-EGFR therapy improved overall survival of patients with metastatic colorectal cancer
Qiu TZ, Chen WS, Li P, Sun J, Gu YH, Chen XF
OncoTargets and Therapy 2018, 11:465-471
Published Date: 22 January 2018

Apatinib-treated advanced medullary thyroid carcinoma: a case report

Chen K, Gao Y, Shi F, Cao G, Bao J
OncoTargets and Therapy 2018, 11:459-463
Published Date: 19 January 2018

Association of clinicopathologic characteristics and outcomes with EZH2 expression in patients with breast cancer in East Azerbaijan, Iran
Boostani F, Dolatkhah R, Fakhrjou A, Farassati F, Sanaat Z
OncoTargets and Therapy 2018, 11:449-457
Published Date: 19 January 2018

Overexpression of LBH is associated with poor prognosis in human hepatocellular carcinoma
Chen JW, Huang CQ, Chen K, Li SM, Zhang X, Cheng J, Cai MY, Xiao Y
OncoTargets and Therapy 2018, 11:441-448
Published Date: 19 January 2018

Long noncoding RNA H19 promotes transforming growth factor-β-induced epithelial–mesenchymal transition by acting as a competing endogenous RNA of miR-370-3p in ovarian cancer cells
Li J, Huang YY, Deng XJ, Luo ML, Wang XF, Hu HY, Liu CD, Zhong M
OncoTargets and Therapy 2018, 11:427-440
Published Date: 18 January 2018


Biosimilar filgrastim vs filgrastim: a multicenter nationwide observational bioequivalence study in patients with chemotherapy-induced neutropenia


Sevinç A, Özkan M, Özet A, Dane F, Öksüzoğlu B, Işıkdoğan A, Özdemir F, Uncu D, Gümüş M, Evrensel T, Yaren A, Kara O, Tekin SB
OncoTargets and Therapy 2018, 11:419-426
Published Date: 18 January 2018

Neoadjuvant chemoradiotherapy followed by surgery in patients with unresectable locally advanced colon cancer: a prospective observational study
Chang H, Yu X, Xiao W, Wang QX, Zhou WH, Zeng ZF, Ding PR, Li L, Gao YH
OncoTargets and Therapy 2018, 11:409-418
Published Date: 17 January 2018

Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway
Daya M, Loilome W, Techasen A, Thanee M, Sa-Ngiamwibool P, Titapun A, Yongvanit P, Namwat N
OncoTargets and Therapy 2018, 11:395-408
Published Date: 18 January 2018

Prognostic role of HSF1 overexpression in solid tumors: a pooled analysis of 3,159 patients
Wan T, Shao J, Hu B, Liu G, Luo P, Zhou Y
OncoTargets and Therapy 2018, 11:383-393
Published Date: 17 January 2018

Comparison of FOLFOX and DOF regimens as first-line treatment in East Asian patients with advanced gastric cancer
Liu M, Hu G, Wang Y, Guo J, Liu L, Han X, Wang Z
OncoTargets and Therapy 2018, 11:375-381
Published Date: 17 January 2018

Combination of betulinic acid with diazen-1-ium-1,2-diolate nitric oxide moiety donating a novel anticancer candidate
Zhang L, Hou S, Li B, Pan J, Jiang L, Zhou G, Gu H, Zhao C, Lu H, Ma F
OncoTargets and Therapy 2018, 11:361-373
Published Date: 15 January 2018

Prognostic role of HSPs in human gastrointestinal cancer: a systematic review and meta-analysis
Ge H, Yan Y, Guo L, Tian F, Wu D
OncoTargets and Therapy 2018, 11:351-359
Published Date: 15 January 2018

Safety and efficacy of transarterial chemoembolization with degradable starch microspheres (DSM-TACE) in the treatment of secondary liver malignancies
Schicho A, Pereira PL, Michalik K, Beyer LP, Stroszczynski C, Wiggermann P
OncoTargets and Therapy 2018, 11:345-350
Published Date: 12 January 2018

The clinical characteristics and prognostic analysis of Chinese advanced NSCLC patients based on circulating tumor DNA sequencing
Rao C, Nie L, Miao X, Xu Y, Li B, Zhang T
OncoTargets and Therapy 2018, 11:337-344
Published Date: 12 January 2018

High-frequency deregulated expression of Wnt signaling pathway members in breast carcinomas
Khan Z, Arafah M, Shaik JP, Mahale A, Alanazi MS
OncoTargets and Therapy 2018, 11:323-335
Published Date: 11 January 2018

The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway
Jia L, Tian Y, Chen Y, Zhang G
OncoTargets and Therapy 2018, 11:313-321
Published Date: 11 January 2018

A novel tumor suppressor gene NCOA5 is correlated with progression in papillary thyroid carcinoma
Zheng Z, Wang Q, Zhang W, Zhang X, Huang D
OncoTargets and Therapy 2018, 11:307-311
Published Date: 11 January 2018

Comparative study of clinical efficacy using three-dimensional and two-dimensional laparoscopies in the treatment of distal gastric cancer
Liu JG, Zhou HT, Qin HQ, Ru HM, Huang JH, Liang SY, Mo XW, Tang WZ
OncoTargets and Therapy 2018, 11:301-306
Published Date: 11 January 2018

Exosome-mediated delivery of MALAT1 induces cell proliferation in breast cancer
Zhang P, Zhou H, Lu K, Lu Y, Wang Y, Feng T
OncoTargets and Therapy 2018, 11:291-299
Published Date: 9 January 2018

Over-expression of ARHGAP18 suppressed cell proliferation, migration, invasion, and tumor growth in gastric cancer by restraining over-activation of MAPK signaling pathways
Li Y, Ji S, Fu L, Jiang T, Wu D, Meng F
OncoTargets and Therapy 2018, 11:279-290
Published Date: 9 January 2018

Experimental study of inhibitory effects of diallyl trisulfide on the growth of human osteosarcoma Saos-2 cells by downregulating expression of glucose-regulated protein 78
Zhang Y, Xie WP, Zhang YK, Chen YQ, Wang DL, Li G, Guan DH
OncoTargets and Therapy 2018, 11:271-277
Published Date: 9 January 2018

A support vector machine and a random forest classifier indicates a 15-miRNA set related to osteosarcoma recurrence
He Y, Ma J, Wang A, Wang W, Luo S, Liu Y, Ye X
OncoTargets and Therapy 2018, 11:253-269
Published Date: 5 January 2018

miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells
Tsai TF, Lin JF, Chou KY, Lin YC, Chen HE, Hwang TIS
OncoTargets and Therapy 2018, 11:239-252
Published Date: 4 January 2018

Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance
Vert A, Castro J, Ribó M, Vilanova M, Benito A
OncoTargets and Therapy 2018, 11:221-237
Published Date: 4 January 2018

RACK1 induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression
Liu B, Wang C, Chen P, Cheng B, Cheng Y
OncoTargets and Therapy 2018, 11:211-220
Published Date: 4 January 2018

KDM2B overexpression correlates with poor prognosis and regulates glioma cell growth
Wang Y, Zang J, Zhang D, Sun Z, Qiu B, Wang X
OncoTargets and Therapy 2018, 11:201-209
Published Date: 8 January 2018

Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/β-catenin signaling
Hu P, Cheng B, He Y, Wei Z, Wu D, Meng Z
OncoTargets and Therapy 2018, 11:193-200
Published Date: 4 January 2018

The effects of naloxone on human breast cancer progression: in vitro and in vivo studies on MDA.MB231 cells
Bimonte S, Barbieri A, Cascella M, Rea D, Palma G, Del Vecchio V, Forte CA, Del Prato F, Arra C, Cuomo A
OncoTargets and Therapy 2018, 11:185-191
Published Date: 3 January 2018

Cancer stem cells, the ultimate targets in cancer therapy
Shabbir A, Esfandyari T, Farassati F
OncoTargets and Therapy 2018, 11:183-184
Published Date: 3 January 2018

Spotlight on midostaurin in the treatment of FLT3-mutated acute myeloid leukemia and systemic mastocytosis: design, development, and potential place in therapy
Weisberg E, Sattler M, Manley PW, Griffin JD
OncoTargets and Therapy 2018, 11:175-182
Published Date: 29 December 2017

Identification of key pathways and genes in TP53 mutation acute myeloid leukemia: evidence from bioinformatics analysis
Huang R, Liao X, Li Q
OncoTargets and Therapy 2018, 11:163-173
Published Date: 28 December 2017

A patient with classic biphasic pulmonary blastoma harboring CD74–ROS1 fusion responds to crizotinib

Meng Z, Chen P, Zang F, Liu Y, Xu X, Su Y, Chen J, Lin L, Zhang L, Zhang T
OncoTargets and Therapy 2018, 11:157-161
Published Date: 28 December 2017

Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy
Castelli G, Pelosi E, Testa U
OncoTargets and Therapy 2018, 11:131-155
Published Date: 28 December 2017

Assessment of the cardiac safety between cetuximab and panitumumab as single therapy in Chinese chemotherapy-refractory mCRC
Tang XM, Chen H, Li Q, Song YL, Zhang SP, Xu XS, Xu YW, Chen SL
OncoTargets and Therapy 2018, 11:123-129
Published Date: 28 December 2017

A retrospective examination of the US Food and Drug Administration’s clinical pharmacology reviews of oncology biologics for potential use of therapeutic drug monitoring
Fleisher B, Ait-Oudhia S
OncoTargets and Therapy 2018, 11:113-121
Published Date: 27 December 2017
The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1
Zhang X, Li P, Ding Z, Wang H, Wang J, Han L, Ding S
OncoTargets and Therapy 2018, 11:103-112
Published Date: 27 December 2017

The RNASEL −1385G/A polymorphism is associated with risk of prostate cancer in Africans
Liu X, Zheng D, Lu G, Yang B
OncoTargets and Therapy 2018, 11:97-102
Published Date: 22 December 2017

Prognosis of patients with primary malignant main stem bronchial tumors: 7,418 cases based on the SEER database
Ma K, Sun F, Yang X, Wang S, Wang L, Jin Y, Shi Y, Jiang W, Zhan C, Wang Q
OncoTargets and Therapy 2018, 11:83-95
Published Date: 22 December 2017

Real-world usage and clinical outcomes of alectinib among post-crizotinib progression anaplastic lymphoma kinase positive non-small-cell lung cancer patients in the USA
DiBonaventura MD, Wong W, Shah-Manek B, Schulz M
OncoTargets and Therapy 2018, 11:75-82
Published Date: 22 December 2017

miR-136 targets MIEN1 and involves the metastasis of colon cancer by suppressing epithelial-to-mesenchymal transition
Ren H, Qi Y, Yin X, Gao J
OncoTargets and Therapy 2018, 11:67-74
Published Date: 22 December 2017

Pretreatment platelet count as a prognostic factor in patients with pancreatic cancer: a systematic review and meta-analysis
Chen S, Na N, Jian Z
OncoTargets and Therapy 2018, 11:59-65
Published Date: 21 December 2017

Clinicopathological and prognostic significance of OCT4 in patients with hepatocellular carcinoma: a meta-analysis
Liang CJ, Xu YC, Ge H, Li GM, Wu JX
OncoTargets and Therapy 2018, 11:47-57
Published Date: 21 December 2017

Upregulated LAMB3 increases proliferation and metastasis in thyroid cancer
Wang Y, Jin Y, Bhandari A, Yao Z, Yang F, Pan Y, Zheng Z, Lv S, Wang O
OncoTargets and Therapy 2018, 11:37-46
Published Date: 21 December 2017

Four-miRNA signature as a prognostic tool for lung adenocarcinoma
Lin Y, Lv Y, Liang R, Yuan C, Zhang J, He D, Zheng X, Zhang J
OncoTargets and Therapy 2018, 11:29-36
Published Date: 21 December 2017

Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway
Gong C, Yang Z, Zhang L, Wang Y, Gong W, Liu Y
OncoTargets and Therapy 2018, 11:17-27
Published Date: 21 December 2017

Identification of epigenetically altered genes and potential gene targets in melanoma using bioinformatic methods
Duan HH, Jiang K, Wei DK, Zhang LJ, Cheng DL, Lv M, Xu YB, He AM
OncoTargets and Therapy 2018, 11:9-15
Published Date: 20 December 2017

ERCC1 rs3212986 A/C polymorphism is not associated with chemotherapy treatment outcomes in gastric cancer patients: evidence from 11 publications in Chinese populations
Tang WW, Wang H, Wang YM, Wang XW
OncoTargets and Therapy 2018, 11:1-8
Published Date: 20 December 2017