OncoTargets and Therapy

M2 macrophages confer resistance to 5-fluorouracil in colorectal cancer through the activation of CCL22/PI3K/AKT signaling

Wei C, Yang C, Wang S, Shi D, Zhang C, Lin X, Xiong B

OncoTargets and Therapy 2019, 12:3051-3063

Published Date: 18 April 2019

ZNF277 regulates ovarian cancer cell proliferation and invasion through inhibition of PTEN

Liu Z, Xu Z, Tian Y, Yan H, Lou Y

OncoTargets and Therapy 2019, 12:3031-3042

Published Date: 18 April 2019

NRF3 suppresses breast cancer cell metastasis and cell proliferation and is a favorable predictor of survival in breast cancer

Sun J, Zheng Z, Chen Q, Pan Y, Lu H, Zhang H, Yu Y, Dai Y

OncoTargets and Therapy 2019, 12:3019-3030

Published Date: 18 April 2019

CD40L inhibits cell growth of THP-1 cells by suppressing the PI3K/Akt pathway

Feng Z, Chen Q, Ren M, Tian Z, Gong Y

OncoTargets and Therapy 2019, 12:3011-3017

Published Date: 18 April 2019

MiR-216b suppresses cell proliferation, migration, invasion, and epithelial–mesenchymal transition by regulating FOXM1 expression in human non-small cell lung cancer

Wang L, Wang Y, Du X, Yao Y, Wang L, Jia Y

OncoTargets and Therapy 2019, 12:2999-3009

Published Date: 18 April 2019

Large-cell neuroendocrine carcinoma of nasal cavity and paranasal sinuses after successful curative therapy: a case report and literature review

Zhao Q, Wei J, Zhang C, Meng L, Wang B, Gao L, Jiang X

OncoTargets and Therapy 2019, 12:2975-2980

Published Date: 17 April 2019

LncRNA MIR100HG promotes cancer cell proliferation, migration and invasion in laryngeal squamous cell carcinoma through the downregulation of miR-204-5p

Huang Y, Zhang C, Zhou Y

OncoTargets and Therapy 2019, 12:2967-2973

Published Date: 17 April 2019

Expression of FOXP1 and FOXO3a in extrahepatic cholangiocarcinoma and the implications in clinicopathological significance and prognosis

He J, Yang Z, Wu Z, Wang L, Xu S, Zou Q, Yuan Y, Li D

OncoTargets and Therapy 2019, 12:2955-2965

Published Date: 17 April 2019

Successful treatment with cryoablation in a patient with bone metastasis in the mid-shaft femur: a case report

Kita K, Nakamura T, Yamanaka T, Yoshida K, Hagi T, Asanuma K, Nakatsuka A, Sudo A

OncoTargets and Therapy 2019, 12:2949-2953

Published Date: 17 April 2019

Case report

Refinement of diagnosis and supporting evidence for the use of immunotherapy through sequential biopsies in a case of EML4-ALK positive lung cancer

Song P, Zhang J, Zhang L

OncoTargets and Therapy 2019, 12:2943-2948

Published Date: 17 April 2019

CD5-negative chronic lymphocytic leukemia/small lymphocytic lymphoma in a patient with gastrointestinal mantle cell lymphoma: an unusual case report

Chen D, Zhan Y, Peng J, Yao F

OncoTargets and Therapy 2019, 12:2937-2941

Published Date: 17 April 2019

A significant response to a combination of trastuzumab and vinorelbine in HER2-negative metastatic breast cancer with HER2 V777L mutation

Lei L, Ye W, Zheng L, Huang P, Shi L, Huang J, Zheng Y, Chen Z, Wang X, Wang X

OncoTargets and Therapy 2019, 12:2931-2936

Published Date: 17 April 2019

Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells

Hao Y, Bai X, Liu X, Kang S, Zhang X, Liu C, Li Z

OncoTargets and Therapy 2019, 12:2921-2930

Published Date: 17 April 2019

Neuropilin-1 is associated with the prognosis of cervical cancer in Henan Chinese population

Yang L, Liu L, Zhu YH, Wang BB, Chen YN, Zhang F, Zhang XA, Ren CC

OncoTargets and Therapy 2019, 12:2911-2920

Published Date: 17 April 2019

MDM2 antagonists as a novel treatment option for acute myeloid leukemia: perspectives on the therapeutic potential of idasanutlin (RG7388)

Khurana A, Shafer DA

OncoTargets and Therapy 2019, 12:2903-2910

Published Date: 16 April 2019

Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling

Liu L, Li Y, Pan B, Zhang T, Wei D, Zhu Y, Guo Y

OncoTargets and Therapy 2019, 12:2891-2902

Published Date: 17 April 2019

Leptin rs7799039 (G2548A) polymorphism is associated with cancer risk: a meta-analysis involving 25,799 subjects

Tang W, Kang M, Liu C, Qiu H

OncoTargets and Therapy 2019, 12:2879-2890

Published Date: 16 April 2019

Notch pathway is involved in the suppression of colorectal cancer by embryonic stem cell microenvironment

Lan G, Lin Z, Zhang J, Liu L, Zhang J, Zheng L, Luo Q

OncoTargets and Therapy 2019, 12:2869-2878

Published Date: 16 April 2019

SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species

Yu W, Yang Z, Huang R, Min Z, Ye M

OncoTargets and Therapy 2019, 12:2861-2868

Published Date: 15 April 2019

Prognostic significance of EIF4G1 in patients with pancreatic ductal adenocarcinoma

Goh TS, Ha M, Lee JS, Jeong DC, Jung ES, Han ME, Kim YH, Oh SO

OncoTargets and Therapy 2019, 12:2853-2859

Published Date: 15 April 2019

FAM111B, a direct target of p53, promotes the malignant process of lung adenocarcinoma

Sun H, Liu K, Huang J, Sun Q, Shao C, Luo J, Xu L, Shen Y, Ren B

OncoTargets and Therapy 2019, 12:2829-2842

Published Date: 17 April 2019

Sunitinib-and-Chinese herbal medicine-based systematic treatment clinically cured a patient with multiple metastatic primary clear cell carcinoma of the liver: a case report

Sun L, Chen H, Xiao Z, Guo W, Lin L

OncoTargets and Therapy 2019, 12:2823-2828

Published Date: 12 April 2019

MicroRNA-940 restricts the expression of metastasis-associated gene MACC1 and enhances the antitumor effect of Anlotinib on colorectal cancer

Wang Y, Zhao M, Zhao H, Cheng S, Bai R, Song M

OncoTargets and Therapy 2019, 12:2809-2822

Published Date: 12 April 2019

Aberrant expression of PAFAH1B3 associates with poor prognosis and affects proliferation and aggressiveness in hypopharyngeal squamous cell carcinoma

Xu J, Zang Y, Cao S, Lei D, Pan X

OncoTargets and Therapy 2019, 12:2799-2808

Published Date: 11 April 2019

Stanniocalcin 1 in tumor microenvironment promotes metastasis of ovarian cancer

Yang Y, Yin S, Li S, Chen Y, Yang L

OncoTargets and Therapy 2019, 12:2789-2798

Published Date: 11 April 2019

Pyrotinib treatment on HER2-positive gastric cancer cells promotes the released exosomes to enhance endothelial cell progression, which can be counteracted by apatinib

Gao Z, Song C, Li G, Lin H, Lian X, Zhang N, Cao B

OncoTargets and Therapy 2019, 12:2777-2787

Published Date: 11 April 2019

The proliferation of cervical cancer is promoted by miRNA-125b through the regulation of the HMGA1

Sun B, Zhang Y, Zhou L, Yin L, Li F, Li C, Xia J

OncoTargets and Therapy 2019, 12:2767-2776

Published Date: 11 April 2019

Rituximab-based combination therapy in patients with Waldenström macroglobulinemia: a systematic review and meta-analysis

Zheng YH, Xu L, Cao C, Feng J, Tang HL, Shu M, Gao GX, Chen X

OncoTargets and Therapy 2019, 12:2751-2766

Published Date: 11 April 2019

Efficacy and safety of apatinib treatment for gastric cancer, hepatocellular carcinoma and non-small cell lung cancer: a meta-analysis [Corrigendum]

Xue J, Astère M, Zhong M, Lin H, Shen J, Zhu Y

OncoTargets and Therapy 2019, 12:2749-2750

Published Date: 11 April 2019

Whole transcriptome sequencing identifies crucial genes associated with colon cancer and elucidation of their possible mechanisms of action

Yang Y, Zhao Y, Zhang W, Bai Y

OncoTargets and Therapy 2019, 12:2737-2747

Published Date: 10 April 2019

Successful treatment of brain radiation necrosis resulting from triple-negative breast cancer with Endostar and short-term hyperbaric oxygen therapy: a case report

Xing S, Fan Z, Shi L, Yang Z, Bai Y

OncoTargets and Therapy 2019, 12:2729-2735

Published Date: 10 April 2019

miR-19 promotes the proliferation of clear cell renal cell carcinoma by targeting the FRK–PTEN axis

Jing ZF, Bi JB, Li ZL, Liu XK, Li J, Zhu YY, Zhang XT, Zhang Z, Li ZH, Kong CZ

OncoTargets and Therapy 2019, 12:2713-2727

Published Date: 10 April 2019

IL-37 promotes cell apoptosis in cervical cancer involving Bim upregulation

Ouyang P, An W, Chen R, Zhang H, Chen D, Jiang E, Zhu W, Li P, Guo H, Chen Z, Wang S

OncoTargets and Therapy 2019, 12:2703-2712

Published Date: 10 April 2019

Clinicopathological impacts of c-Met overexpression in bladder cancer: evidence from 1,336 cases

Xu X, Zhang G, He L, Zhu Y

OncoTargets and Therapy 2019, 12:2695-2702

Published Date: 10 April 2019

Overexpression of PRR11 promotes tumorigenic capability and is associated with progression in esophageal squamous cell carcinoma

Zhou L, Deng Z, Li H, Jiang N, Wei Z, Hong M, Wang J, Zhang M, Shi Y, Lu Z, Huang X

OncoTargets and Therapy 2019, 12:2677-2693

Published Date: 9 April 2019

Cell-free miR-17-5p as a diagnostic biomarker for gastric cancer inhibits dendritic cell maturation

Cui ZJ, Xie XL, Qi W, Yang YC, Bai Y, Han J, Ding Q, Jiang HQ

OncoTargets and Therapy 2019, 12:2661-2675

Published Date: 9 April 2019

lncRNA KCNQ1OT1 enhances the chemoresistance of oxaliplatin in colon cancer by targeting the miR-34a/ATG4B pathway

Li Y, Li C, Li D, Yang L, Jin J, Zhang B

OncoTargets and Therapy 2019, 12:2649-2660

Published Date: 9 April 2019

High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center

Li Y, Fang D, Bao Z, He A, Guan B, He S, Zhan Y, Gong Y, Li X, Zhou L

OncoTargets and Therapy 2019, 12:2635-2648

Published Date: 11 April 2019

Diagnostic value of circular RNAs as effective biomarkers for cancer: a systematic review and meta-analysis

Tan H, Gan L, Fan X, Liu L, Liu S

OncoTargets and Therapy 2019, 12:2623-2633

Published Date: 10 April 2019

miRNA-99b-5p targets FZD8 to inhibit non-small cell lung cancer proliferation, migration and invasion

Liu R, Chen Y, Shou T, Hu J, Qing C

OncoTargets and Therapy 2019, 12:2615-2621

Published Date: 8 April 2019

Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression

Liu T, Sun X, Cao Z

OncoTargets and Therapy 2019, 12:2605-2614

Published Date: 9 April 2019

Long noncoding RNA LINC00515 promotes cell proliferation and inhibits apoptosis by sponging miR-16 and activating PRMT5 expression in human glioma

Wu Z, Lin Y

OncoTargets and Therapy 2019, 12:2595-2604

Published Date: 8 April 2019

SMYD2-OE promotes oxaliplatin resistance in colon cancer through MDR1/P-glycoprotein via MEK/ERK/AP1 pathway

Ren H, Wang Z, Chen Y, Liu Y, Zhang S, Zhang T, Li Y

OncoTargets and Therapy 2019, 12:2585-2594

Published Date: 8 April 2019

Clinical efficacy and survival analysis of apatinib combined with docetaxel in advanced esophageal cancer

Li J, Jia YX, Gao YP, Chang ZW, Han HQ, Yan J, Qin YR

OncoTargets and Therapy 2019, 12:2577-2583

Published Date: 8 April 2019

LncRNA PVT1 promotes proliferation, invasion and epithelial–mesenchymal transition of renal cell carcinoma cells through downregulation of miR-16-5p

Ren Y, Huang W, Weng G, Cui P, Liang H, Li Y

OncoTargets and Therapy 2019, 12:2563-2575

Published Date: 5 April 2019

Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53

Weng C, Chen Y, Wu Y, Liu X, Mao H, Fang X, Li B, Wang L, Guan M, Liu G, Lu L, Yuan Y

OncoTargets and Therapy 2019, 12:2553-2561

Published Date: 8 April 2019

The diagnostic value of circulating tumor cells and ctDNA for gene mutations in lung cancer

Lyu M, Zhou J, Ning K, Ying B

OncoTargets and Therapy 2019, 12:2539-2552

Published Date: 5 April 2019

Long-term response of metastatic renal clear cell carcinoma following a subcutaneous injection of mixed bacterial vaccine: a case report

Chen J, Lv Y, Mu F, Xu K

OncoTargets and Therapy 2019, 12:2531-2538

Published Date: 5 April 2019

SIRT1 inhibits hepatocellular carcinoma metastasis by promoting M1 macrophage polarization via NF-κB pathway

Zhou B, Yang Y, Li C

OncoTargets and Therapy 2019, 12:2519-2529

Published Date: 4 April 2019

Clinical outcome of osteosarcoma and its correlation with programmed death-ligand 1 and T cell activation markers

Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, Okano S, Ideta H, Kamanaka T, Sobajima A, Takizawa T, Kito M, Aoki K, Uemura T, Haniu H, Kato H, Saito N

OncoTargets and Therapy 2019, 12:2513-2518

Published Date: 3 April 2019

Durvalumab for the management of urothelial carcinoma: a short review on the emerging data and therapeutic potential

Baldini C, Champiat S, Vuagnat P, Massard C

OncoTargets and Therapy 2019, 12:2505-2512

Published Date: 3 April 2019

Association of polymorphisms in MALAT1 with the risk of esophageal squamous cell carcinoma in a Chinese population

Qu Y, Shao N, Yang W, Wang J, Cheng Y

OncoTargets and Therapy 2019, 12:2495-2503

Published Date: 3 April 2019

Combination treatment with cetuximab in advanced nasopharyngeal carcinoma patients: a meta-analysis

Shen J, Sun C, Zhou M, Zhang Z

OncoTargets and Therapy 2019, 12:2477-2494

Published Date: 3 April 2019

SOX5 promotes cell invasion and metastasis via activation of Twist-mediated epithelial–mesenchymal transition in gastric cancer

You J, Zhao Q, Fan X, Wang J

OncoTargets and Therapy 2019, 12:2465-2476

Published Date: 3 April 2019

LKB1 suppresses glioma cell invasion via NF-κB/Snail signaling repression

Yuan Y, Li SL, Cao YL, Li JJ, Wang QP

OncoTargets and Therapy 2019, 12:2451-2463

Published Date: 2 April 2019

Differentiation antagonizing non-protein coding RNA modulates the proliferation, migration, and angiogenesis of glioma cells by targeting the miR-216a/LGR5 axis and the PI3K/AKT signaling pathway

Wang W, Li Y, Ma Q, Yan H, Su W

OncoTargets and Therapy 2019, 12:2439-2449

Published Date: 4 April 2019

Hepatopulmonary syndrome after radiofrequency ablation of recurrent intrahepatic cholangiocarcinoma: a case report

Wang Y, Ma K, Zhong A, Xiong Q, Chen J

OncoTargets and Therapy 2019, 12:2431-2438

Published Date: 2 April 2019

Clinical treatment of advanced synchronous triple primary malignancies: comprehensive treatment based on targeted therapy

Zhang Y, Ge Y, Wu X, Liu S

OncoTargets and Therapy 2019, 12:2421-2430

Published Date: 2 April 2019

Histone deacetylase 6 is overexpressed and promotes tumor growth of colon cancer through regulation of the MAPK/ERK signal pathway

Zhang SL, Zhu HY, Zhou BY, Chu Y, Huo JR, Tan YY, Liu DL

OncoTargets and Therapy 2019, 12:2409-2419

Published Date: 2 April 2019

SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism

Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G

OncoTargets and Therapy 2019, 12:2397-2408

Published Date: 28 March 2019

Luteolin suppresses tumor proliferation through inducing apoptosis and autophagy via MAPK activation in glioma

You Y, Wang R, Shao N, Zhi F, Yang Y

OncoTargets and Therapy 2019, 12:2383-2396

Published Date: 28 March 2019

Overexpression of miR-664 is associated with poor overall survival and accelerates cell proliferation, migration and invasion in hepatocellular carcinoma

Wang X, Zhou Z, Zhang T, Wang M, Xu R, Qin S, Zhang S

OncoTargets and Therapy 2019, 12:2373-2381

Published Date: 28 March 2019

Postchemotherapy sarcoma as a somatic-type malignancy derived from the gonadal yolk sac tumor in a patient with 46, XY pure gonadal dysgenesis

Zong X, Yang JX, Zhang Y, Cao DY, Shen K, You Y, Guo LN

OncoTargets and Therapy 2019, 12:2365-2372

Published Date: 28 March 2019

Tumor necrosis factor α knockout impaired tumorigenesis in chronic myeloid leukemia cells partly by metabolism modification and miRNA regulation

Shen N, Liu S, Cui J, Li Q, You Y, Zhong Z, Cheng F, Guo AY, Zou P, Yuan G, Zhu X

OncoTargets and Therapy 2019, 12:2355-2364

Published Date: 29 March 2019

1,25-Dihydroxyvitamin D3 affects gastric cancer progression by repressing BMP3 promoter methylation

Zhao Y, Cai LL, Wang HL, Shi XJ, Ye HM, Song P, Huang BQ, Tzeng CM

OncoTargets and Therapy 2019, 12:2343-2353

Published Date: 28 March 2019

Comparison of CHOP vs CHOPE for treatment of peripheral T-cell lymphoma: a meta-analysis

Deng S, Lin S, Shen J, Zeng Y

OncoTargets and Therapy 2019, 12:2335-2342

Published Date: 28 March 2019

MicroRNA-221 promotes papillary thyroid carcinoma cells migration and invasion via targeting RECK and regulating epithelial–mesenchymal transition

Wei Z, Gao A, Wang Q, Lou X, Zhao J, Lu Q

OncoTargets and Therapy 2019, 12:2323-2333

Published Date: 28 March 2019

Molecular subtype classification of papillary renal cell cancer using miRNA expression

Yu C, Dai D, Xie J

OncoTargets and Therapy 2019, 12:2311-2322

Published Date: 29 March 2019

Development and validation of prognostic nomograms for medullary thyroid cancer

Guan Y, Fang S, Chen L, Li Z

OncoTargets and Therapy 2019, 12:2299-2309

Published Date: 27 March 2019

TRIM31 promotes glioma proliferation and invasion through activating NF-κB pathway

Zhou L, Deng ZZ, Li HY, Jiang N, Wei ZS, Hong MF, Chen XD, Wang JH, Zhang MX, Shi YH, Lu ZQ, Huang XM

OncoTargets and Therapy 2019, 12:2289-2297

Published Date: 27 March 2019

Management of recurrent Ewing sarcoma: challenges and approaches

Van Mater D, Wagner L

OncoTargets and Therapy 2019, 12:2279-2288

Published Date: 27 March 2019

Selecting treatment options in refractory metastatic colorectal cancer

Byrne M, Saif MW

OncoTargets and Therapy 2019, 12:2271-2278

Published Date: 27 March 2019

A novel curcumin derivative CL-6 exerts antitumor effect in human gastric cancer cells by inducing apoptosis through Hippo–YAP signaling pathway

Ye C, Wang W, Xia G, Yu C, Yi Y, Hua C, Tu F, Shen L, Chen C, Sun W, Zheng Z

OncoTargets and Therapy 2019, 12:2259-2269

Published Date: 27 March 2019

MDM2 promotes epithelial–mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma

Tang Y, Xuan Y, Qiao G, Ou Z, He Z, Zhu Q, Liao M, Yin G

OncoTargets and Therapy 2019, 12:2247-2258

Published Date: 27 March 2019

TRIB3 suppresses proliferation and invasion and promotes apoptosis of endometrial cancer cells by regulating the AKT signaling pathway

Qu J, Liu B, Li B, Du G, Li Y, Wang J, He L, Wan X

OncoTargets and Therapy 2019, 12:2235-2245

Published Date: 27 March 2019

Effect of Th9/IL-9 on the growth of gastric cancer in nude mice

Cai L, Zhang Y, Zhang Y, Chen H, Hu J

OncoTargets and Therapy 2019, 12:2225-2234

Published Date: 26 March 2019

The impact of adjuvant radiotherapy on molecular prognostic markers in gliomas

Harat M, Blok M, Harat A, Soszyńska K

OncoTargets and Therapy 2019, 12:2215-2224

Published Date: 26 March 2019

Efficacy of on-demand intrahepatic arterial therapy in combination with sorafenib for advanced hepatocellular carcinoma

Tajiri K, Futsukaichi Y, Kobayashi S, Nagata K, Yasumura S, Takahara T, Minemura M, Yasuda I

OncoTargets and Therapy 2019, 12:2205-2214

Published Date: 26 March 2019

LINC01296 promotes proliferation, migration, and invasion of HCC cells by targeting miR-122-5P and modulating EMT activity

Wan Y, Li M, Huang P

OncoTargets and Therapy 2019, 12:2193-2203

Published Date: 26 March 2019

Delayed remission following sequential infusion of humanized CD19- and CD22-modified CAR-T cells in a patient with relapsed/refractory acute lymphoblastic leukemia and prior exposure to murine-derived CD19-directed CAR-T cells

Yang F, Zhang J, Zhang X, Tian M, Wang J, Kang L, Qiu H, Wu D

OncoTargets and Therapy 2019, 12:2187-2191

Published Date: 25 March 2019

A case of small-cell lung cancer with adrenocorticotropic hormone deficiency induced by nivolumab

Zhu Y, Wu HH, Wang W

OncoTargets and Therapy 2019, 12:2181-2186

Published Date: 25 March 2019

The role of IRAK1 in breast cancer patients treated with neoadjuvant chemotherapy

Yang M, Qin X, Qin G, Zheng X

OncoTargets and Therapy 2019, 12:2171-2180

Published Date: 25 March 2019

Weekly alternate intensive regimen FIrB/FOx in metastatic colorectal cancer patients: an update from clinical practice

Cortellini A, Cannita K, Parisi A, Lanfiuti Baldi P, Venditti O, D'Orazio C, Dal Mas A, Calvisi G, Giordano AV, Vicentini V, Vicentini R, Felicioni L, Marchetti A, Buttitta F, Russo A, Ficorella C

OncoTargets and Therapy 2019, 12:2159-2170

Published Date: 25 March 2019

miR-1-3p suppresses proliferation of hepatocellular carcinoma through targeting SOX9

Zhang H, Zhang Z, Gao L, Qiao Z, Yu M, Yu B, Yang T

OncoTargets and Therapy 2019, 12:2149-2157

Published Date: 22 March 2019

CDK7 inhibitor suppresses tumor progression through blocking the cell cycle at the G2/M phase and inhibiting transcriptional activity in cervical cancer

Zhong S, Zhang Y, Yin X, Di W

OncoTargets and Therapy 2019, 12:2137-2147

Published Date: 22 March 2019

Review

Research status and progress of the RNA or protein biomarkers for prostate cancer

Song C, Chen H, Song C

OncoTargets and Therapy 2019, 12:2123-2136

Published Date: 22 March 2019

SUVmax and metabolic tumor volume: surrogate image biomarkers of KRAS mutation status in colorectal cancer

Lv Y, Wang X, Liang L, Wang L, Lu J

OncoTargets and Therapy 2019, 12:2115-2121

Published Date: 21 March 2019

Elevated nuclear auto-antigenic sperm protein promotes melanoma progression by inducing cell proliferation

Li JX, Wei CY, Cao SG, Xia MW

OncoTargets and Therapy 2019, 12:2105-2113

Published Date: 21 March 2019

Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer

Liu Z, Yu M, Fei B, Sun J, Wang D

OncoTargets and Therapy 2019, 12:2095-2104

Published Date: 20 March 2019

Two cases of lymphangitic carcinomatosis as the primary symptom of colorectal carcinoma that achieved complete remission using combination anti-EGFR antibody therapy

Toshima H, Ikusue T, Hisamatsu A, Kobayashi K, Shimada K

OncoTargets and Therapy 2019, 12:2089-2093

Published Date: 20 March 2019

Anti-PD1 up-regulates PD-L1 expression and inhibits T-cell lymphoma progression: possible involvement of an IFN-γ-associated JAK-STAT pathway

Xue W, Li W, Zhang T, Li Z, Wang Y, Qiu Y, Wang Y, Chen C, Fu D, Zhang M

OncoTargets and Therapy 2019, 12:2079-2088

Published Date: 19 March 2019

Effect of 21-gene recurrence score in decision-making for surgery in early stage breast cancer

Wu SG, Zhang WW, Wang J, Dong Y, Chen YX, He ZY

OncoTargets and Therapy 2019, 12:2071-2078

Published Date: 19 March 2019

Elevated expression of microRNA-328-3p suppresses aggressive malignant behaviors via targeting matrix metalloprotease 16 in osteosarcoma

Zhang M, Zhang J, Zhou Q

OncoTargets and Therapy 2019, 12:2063-2070

Published Date: 18 March 2019

Spotlight on aldoxorubicin (INNO-206) and its potential in the treatment of soft tissue sarcomas: evidence to date

Cranmer LD

OncoTargets and Therapy 2019, 12:2047-2062

Published Date: 18 March 2019

Paradoxical effects of cellular senescence-inhibited gene involved in hepatocellular carcinoma migration and proliferation by ERK pathway and mesenchymal-like markers

Cheng Q, Tong TJ, Li Z, Hu S, Chen D, Wang SQ, Zhu JY

OncoTargets and Therapy 2019, 12:2035-2046

Published Date: 15 March 2019

Microcalcification and BMP-2 in breast cancer: correlation with clinicopathological features and outcomes

Zhang L, Hao C, Wu Y, Zhu Y, Ren Y, Tong Z

OncoTargets and Therapy 2019, 12:2023-2033

Published Date: 15 March 2019

Curcumin inhibits the proliferation and invasion of MG-63 cells through inactivation of the p-JAK2/p-STAT3 pathway

Sun Y, Liu L, Wang Y, He A, Hu H, Zhang J, Han M, Huang Y

OncoTargets and Therapy 2019, 12:2011-2021

Published Date: 15 March 2019

Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis

Shi W, Dong F, Jiang Y, Lu L, Wang C, Tan J, Yang W, Guo H, Ming J, Huang T

OncoTargets and Therapy 2019, 12:1979-2010

Published Date: 15 March 2019

Downregulation of MMSET impairs breast cancer proliferation and metastasis through inhibiting Wnt/β-catenin signaling

Zhao X, Xie T, Zhao W, Cai W, Su X

OncoTargets and Therapy 2019, 12:1965-1977

Published Date: 14 March 2019

Elevated apolipoprotein B predicts poor postsurgery prognosis in patients with hepatocellular carcinoma

Yan X, Yao M, Wen X, Zhu Y, Zhao E, Qian X, Chen X, Lu W, Lv Q, Zhang L, Lu F

OncoTargets and Therapy 2019, 12:1957-1964

Published Date: 12 March 2019

Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin

Dong C, Liu X, Wang H, Li J, Dai L, Li J, Xu Z

OncoTargets and Therapy 2019, 12:1947-1956

Published Date: 12 March 2019

Mechanisms of drug resistance in acute myeloid leukemia

Zhang J, Gu Y, Chen B

OncoTargets and Therapy 2019, 12:1937-1945

Published Date: 11 March 2019

Long noncoding RNA STXBP5-AS1 inhibits cell proliferation, migration, and invasion through inhibiting the PI3K/AKT signaling pathway in gastric cancer cells

Cen D, Huang H, Yang L, Guo K, Zhang J

OncoTargets and Therapy 2019, 12:1929-1936

Published Date: 8 March 2019

Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma

Qin H, Li Y, Zhang H, Wang F, He H, Bai X, Li S

OncoTargets and Therapy 2019, 12:1917-1927

Published Date: 8 March 2019

lncRNAs as potential molecular biomarkers in the clinicopathology and prognosis of cholangiocarcinoma: a systematic review and meta-analysis

Dai K, Quan J, Yan F, Jin X, Pan X, Song X, Zhang S, Ren Q, Liu J, Liu X

OncoTargets and Therapy 2019, 12:1905-1915

Published Date: 8 March 2019

MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA

Peng T, Li Z, Li D, Wang S

OncoTargets and Therapy 2019, 12:1893-1903

Published Date: 8 March 2019

Neoadjuvant chemotherapy with radical surgery vs radical surgery alone for cervical cancer: a systematic review and meta-analysis

Zhao H, He Y, Yang S, Zhao Q, Wu Y

OncoTargets and Therapy 2019, 12:1881-1891

Published Date: 7 March 2019

ROS generation and autophagosome accumulation contribute to the DMAMCL-induced inhibition of glioma cell proliferation by regulating the ROS/MAPK signaling pathway and suppressing the Akt/mTOR signaling pathway

Wang Y, Zhang J, Yang Y, Liu Q, Xu G, Zhang R, Pang Q

OncoTargets and Therapy 2019, 12:1867-1880

Published Date: 7 March 2019

Targeting off-target effects: endoplasmic reticulum stress and autophagy as effective strategies to enhance temozolomide treatment

He Y, Su J, Lan B, Gao Y, Zhao J

OncoTargets and Therapy 2019, 12:1857-1865

Published Date: 7 March 2019

A case report for severe hand–foot skin reaction caused by chemotherapy with actinomycin D in a patient with oculocutaneous albinism

Yan SJ, Li Y, Li ZL, Chen Y, Zhang XH, Xiao L

OncoTargets and Therapy 2019, 12:1851-1855

Published Date: 8 March 2019

Lipid nanobubbles as an ultrasound-triggered artesunate delivery system for imaging-guided, tumor-targeted chemotherapy

Gao S, Cheng X, Li J

OncoTargets and Therapy 2019, 12:1841-1850

Published Date: 6 March 2019

Ubiquitin-specific protease 4 promotes glioblastoma multiforme via activating ERK pathway

Zhou Y, Liang P, Ji W, Yu Z, Chen H, Jiang L

OncoTargets and Therapy 2019, 12:1825-1839

Published Date: 5 March 2019

The overexpression of Rab9 promotes tumor progression regulated by XBP1 in breast cancer

Liu Y, Wang X, Zhang Z, Xiao B, An B, Zhang J

OncoTargets and Therapy 2019, 12:1815-1824

Published Date: 4 March 2019

Elevated HOXA13 expression promotes the proliferation and metastasis of gastric cancer partly via activating Erk1/2

Qin Z, Chen Z, Weng J, Li S, Rong Z, Zhou C

OncoTargets and Therapy 2019, 12:1803-1813

Published Date: 4 March 2019

A meta-analysis of the efficacy and safety of PD-1/PD-L1 immune checkpoint inhibitors as treatments for metastatic bladder cancer

Fan Z, Liang Y, Yang X, Li B, Cui L, Luo L, Jia Y, Wang Y, Niu H

OncoTargets and Therapy 2019, 12:1791-1801

Published Date: 4 March 2019

Targeting Trop-2 in solid tumors: future prospects

Zaman S, Jadid H, Denson AC, Gray JE

OncoTargets and Therapy 2019, 12:1781-1790

Published Date: 1 March 2019

Genetic ablation of TAZ induces HepG2 liver cancer cell apoptosis through activating the CaMKII/MIEF1 signaling pathway

Hou Y, Lan C, Kong Y, Zhu C, Peng W, Huang Z, Zhang C

OncoTargets and Therapy 2019, 12:1765-1779

Published Date: 1 March 2019

Upregulated expression of ACTL8 contributes to invasion and metastasis and indicates poor prognosis in colorectal cancer

Han Q, Sun ML, Liu WS, Zhao HS, Jiang LY, Yu ZJ, Wei MJ

OncoTargets and Therapy 2019, 12:1749-1763

Published Date: 1 March 2019

Single institution experience of split course radiotherapy in patients with desmoid tumors

Luo J, Jin K, Qian S, Ma X, Pan Z, Yao W, Zhang Z, Guo X, Yu X

OncoTargets and Therapy 2019, 12:1741-1748

Published Date: 7 March 2019

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function

Zhou L, Liu LL, Chai W, Zhao T, Jin X, Guo XX, Han LY, Yuan CL

OncoTargets and Therapy 2019, 12:1729-1739

Published Date: 28 February 2019

Original Research

Everolimus for the treatment of advanced gastrointestinal or lung nonfunctional neuroendocrine tumors in East Asian patients: a subgroup analysis of the RADIANT-4 study

Yao JC, Oh DY, Qian JM, Park YS, Herbst F, Ridolfi A, Izquierdo M, Ito T, Jia LQ, Komoto I, Sriuranpong V, Shimada Y

OncoTargets and Therapy 2019, 12:1717-1728

Published Date: 28 February 2019

CD24 isoform a promotes cell proliferation, migration and invasion and is downregulated by EGR1 in hepatocellular carcinoma

Li L, Chen J, Ge C, Zhao F, Chen T, Tian H, Li J, Li H

OncoTargets and Therapy 2019, 12:1705-1716

Published Date: 28 February 2019

RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma

Yan Y, Xu H, Zhang L, Zhou X, Qian X, Zhou J, Huang Y, Ge W, Wang W

OncoTargets and Therapy 2019, 12:1691-1703

Published Date: 28 February 2019

Concurrent apatinib and docetaxel vs apatinib monotherapy as third- or subsequent-line therapy for advanced gastric adenocarcinoma: a retrospective study

Lin H, Han D, Fu G, Liu C, Wang L, Han S, Liu B, Yu J

OncoTargets and Therapy 2019, 12:1681-1689

Published Date: 28 February 2019

Effects of various interventions on the occurrence of macrovascular invasion of hepatocellular carcinoma after the baseline serum γ-glutamyltransferase stratification

Liu Y, Zhang Q, Yang X, Li Y, Zhu B, Niu S, Huang Y, Hu Y, Wang X

OncoTargets and Therapy 2019, 12:1671-1679

Published Date: 28 February 2019

Clinical utility of a novel natural killer cell activity assay for diagnosing non-small cell lung cancer: a prospective pilot study

Choi SI, Lee SH, Park JY, Kim KA, Lee EJ, Lee SY, In KH

OncoTargets and Therapy 2019, 12:1661-1669

Published Date: 27 February 2019

The contribution of ABCG2 G34A and C421A polymorphisms to multiple myeloma susceptibility

Niebudek K, Balcerczak E, Mirowski M, Pietrzak J, Zawadzka I, Żebrowska-Nawrocka M

OncoTargets and Therapy 2019, 12:1655-1660

Published Date: 27 February 2019

TCTP promotes epithelial–mesenchymal transition in lung adenocarcinoma

Sun R, Lu X, Gong L, Jin F

OncoTargets and Therapy 2019, 12:1641-1653

Published Date: 27 February 2019

ARQ-197 enhances the antitumor effect of sorafenib in hepatocellular carcinoma cells via decelerating its intracellular clearance

Gao X, Chen H, Huang X, Li H, Liu Z, Bo X

OncoTargets and Therapy 2019, 12:1629-1640

Published Date: 26 February 2019

Nab-paclitaxel in pretreated metastatic breast cancer: evaluation of activity, safety, and quality of life

De Luca R, Profita G, Cicero G

OncoTargets and Therapy 2019, 12:1621-1627

Published Date: 26 February 2019

The accumulation of metabolic syndrome components is associated with higher risk of positive surgical margin among patients with localized prostate cancer after radical prostatectomy

Zheng X, Qiu S, Liao X, Han X, Jin K, Yang L, Wei Q

OncoTargets and Therapy 2019, 12:1613-1620

Published Date: 26 February 2019

Ubiquitin-specific peptidase 28 enhances STAT3 signaling and promotes cell growth in non-small-cell lung cancer

Li P, Huang Z, Wang J, Chen W, Huang J

OncoTargets and Therapy 2019, 12:1603-1611

Published Date: 26 February 2019

Primary poorly differentiated small cell type neuroendocrine carcinoma of the hypopharynx

Ao YJ, Zhou SH

OncoTargets and Therapy 2019, 12:1593-1601

Published Date: 27 February 2019

Management of recurrent nasopharyngeal carcinoma: current perspectives

Perri F, Della Vittoria Scarpati G, Caponigro F, Ionna F, Longo F, Buonopane S, Muto P, Di Marzo M, Pisconti S, Solla R

OncoTargets and Therapy 2019, 12:1583-1591

Published Date: 26 February 2019

MLL3 promotes the senescence of esophageal squamous cell carcinoma

Xia M, Ling F, Gao F, Tao C

OncoTargets and Therapy 2019, 12:1575-1582

Published Date: 1 March 2019

Original Research

Deleted in breast cancer 1 as a potential prognostic biomarker in human cancers: a pooled analysis of 2,254 patients

Liu G, Wu Q, Wang Y, Xiong Q, Fu F

OncoTargets and Therapy 2019, 12:1563-1574

Published Date: 22 February 2019

NACT + IMRT versus NACT + IMRT + CCRT in locoregionally advanced NPC patients: a retrospective study

Chen X, Zhu X, Wang J, Liu J, Ji R

OncoTargets and Therapy 2019, 12:1553-1562

Published Date: 22 February 2019

Caveolin-1: a multifaceted driver of breast cancer progression and its application in clinical treatment

Qian XL, Pan YH, Huang QY, Shi YB, Huang QY, Hu ZZ, Xiong LX

OncoTargets and Therapy 2019, 12:1539-1552

Published Date: 27 February 2019

Development of treatment options for Chinese patients with advanced squamous cell lung cancer: focus on afatinib

Lu S

OncoTargets and Therapy 2019, 12:1521-1538

Published Date: 22 February 2019

Downregulation of KLF13 through DNMT1-mediated hypermethylation promotes glioma cell proliferation and invasion

Wu R, Yun Q, Zhang JP, Bao J

OncoTargets and Therapy 2019, 12:1509-1520

Published Date: 22 February 2019

The surgical perspective in precision treatment of diffuse gliomas

Thon N, Tonn JC, Kreth FW

OncoTargets and Therapy 2019, 12:1497-1508

Published Date: 22 February 2019

Sympathetic innervation contributes to perineural invasion of salivary adenoid cystic carcinoma via the β2-adrenergic receptor

Ma C, Gao T, Ju J, Zhang Y, Ni Q, Li Y, Zhao Z, Chai J, Yang X, Sun M

OncoTargets and Therapy 2019, 12:1475-1495

Published Date: 21 February 2019

BRAF mutation in cytologically indeterminate thyroid nodules: after reclassification of a variant thyroid carcinoma

Pongsapich W, Chongkolwatana C, Poungvarin N, Amornpichetkul K, Piyawattayakorn N, Vejvisithsakul P, Maneeprasopchoke P

OncoTargets and Therapy 2019, 12:1465-1473

Published Date: 21 February 2019

Spotlight on liposomal irinotecan for metastatic pancreatic cancer: patient selection and perspectives

Woo W, Carey ET, Choi M

OncoTargets and Therapy 2019, 12:1455-1463

Published Date: 21 February 2019

IL-27 inhibits non-small-cell lung cancer cell metastasis by miR-935 in vitro

Wang T, Chen Y, Nie H, Huang Y, Zhao Y, Yang J

OncoTargets and Therapy 2019, 12:1447-1454

Published Date: 21 February 2019

Impact of liver kinase B1 on p53 and survivin and its correlation with prognosis in gastric cancer

Li W, Luo S, Ma G, Wang L

OncoTargets and Therapy 2019, 12:1439-1445

Published Date: 22 February 2019

Multiple extramedullary plasmacytomas of the trachea and pharyngeal tissue: a case report and literature review

Tang R, Wang Y, Liang C, Li W, Pei L, Kang J, Hou G

OncoTargets and Therapy 2019, 12:1433-1437

Published Date: 20 February 2019

Extracellular matrix protein 1 (ECM1) is associated with carcinogenesis potential of human bladder cancer

Wang Z, Zhou Q, Li A, Huang W, Cai Z, Chen W

OncoTargets and Therapy 2019, 12:1423-1432

Published Date: 20 February 2019

First-line tyrosine kinase inhibitors in EGFR mutation-positive non-small-cell lung cancer: a network meta-analysis

Holleman MS, van Tinteren H, Groen HJM, Al MJ, Uyl-de Groot CA

OncoTargets and Therapy 2019, 12:1413-1421

Published Date: 20 February 2019

Bioinformatic analysis of miR-4792 regulates Radix Tetrastigma hemsleyani flavone to inhibit proliferation, invasion, and induce apoptosis of A549 cells

Liu P, Pu J, Zhang J, Chen Z, Wei K, Shi L

OncoTargets and Therapy 2019, 12:1401-1412

Published Date: 20 February 2019

Merkel cell carcinoma metastatic to cervical lymph node in a patient with rheumatoid arthritis: a case report

Li N, Wang G, Jiang X, Huang M, Tian H, Xuan F, Zhang Y, Lv Y, Hu M, Wang Z, Ren P, Xu M

OncoTargets and Therapy 2019, 12:1395-1400

Published Date: 19 February 2019

Brain metastases from breast cancer may respond to endocrine therapy: report of two cases

Wang Q, Sun B, Liu C, Shi S, Ding L, Liu J, Wu S

OncoTargets and Therapy 2019, 12:1389-1393

Published Date: 19 February 2019

CT-guided cryoablation for unresectable pelvic recurrent colorectal cancer: a retrospective study

Wang Y, He XH, Xu LC, Huang HZ, Li GD, Wang YH, Li WT, Wang GZ

OncoTargets and Therapy 2019, 12:1379-1387

Published Date: 19 February 2019

lncRNA MALAT1 potentiates the progression of tongue squamous cell carcinoma through regulating miR-140-5p-PAK1 pathway

Zhu M, Zhang C, Chen D, Chen S, Zheng H

OncoTargets and Therapy 2019, 12:1365-1377

Published Date: 19 February 2019

Stereotactic body radiation therapy for pulmonary large cell neuroendocrine carcinoma: a case report

Jo IY, Yeo SG

OncoTargets and Therapy 2019, 12:1359-1364

Published Date: 18 February 2019

lncRNA SLCO4A1-AS1 promotes growth and invasion of bladder cancer through sponging miR-335-5p to upregulate OCT4

Yang Y, Wang F, Huang H, Zhang Y, Xie H, Men T

OncoTargets and Therapy 2019, 12:1351-1358

Published Date: 18 February 2019

Irreversible electroporation combined with chemotherapy for unresectable pancreatic carcinoma: a prospective cohort study

Liu S, Qin Z, Xu J, Zeng J, Chen J, Niu L, Xu M

OncoTargets and Therapy 2019, 12:1341-1350

Published Date: 18 February 2019

Treatment of adult brainstem glioma with combined antiangiogenic therapy: a case report and literature review

Yu D, Han G, Liu H, Gao L, Verma V

OncoTargets and Therapy 2019, 12:1333-1339

Published Date: 18 February 2019

Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis

Yang K, Gao J, Luo M

OncoTargets and Therapy 2019, 12:1319-1331

Published Date: 18 February 2019

High expression of NUCB2 promotes papillary thyroid cancer cells proliferation and invasion

Zhao J, Yun X, Ruan X, Chi J, Yu Y, Li Y, Zheng X, Gao M

OncoTargets and Therapy 2019, 12:1309-1318

Published Date: 18 February 2019

Potent in vitro and xenograft antitumor activity of a novel agent, PV-10, against relapsed and refractory neuroblastoma

Swift L, Zhang C, Trippett T, Narendran A

OncoTargets and Therapy 2019, 12:1293-1307

Published Date: 18 February 2019

Ten years of research on the role of BVES/POPDC1 in human disease: a review

Han P, Lei Y, Li D, Liu J, Yan W, Tian D

OncoTargets and Therapy 2019, 12:1279-1291

Published Date: 18 February 2019

Correlations of lncRNAs with cervical lymph node metastasis and prognosis of papillary thyroid carcinoma

Li N, Cui M, Yu P, Li Q

OncoTargets and Therapy 2019, 12:1269-1278

Published Date: 18 February 2019

Moderate hypofractionated radiotherapy vs conventional fractionated radiotherapy in localized prostate cancer: a systemic review and meta-analysis from Phase III randomized trials

Yin Z, You J, Wang YY, Zhao J, Jiang S, Zhang X, Wang P, Tao Z, Wang X, Yuan Z

OncoTargets and Therapy 2019, 12:1259-1268

Published Date: 15 February 2019

Upregulation of STC2 in colorectal cancer and its clinicopathological significance

Zhang C, Chen S, Ma X, Yang Q, Su F, Shu X, Xie W, Feng M, Xiong B

OncoTargets and Therapy 2019, 12:1249-1258

Published Date: 15 February 2019

Optimal postoperative adjuvant treatment strategy for HBV-related hepatocellular carcinoma with microvascular invasion: a propensity score analysis

Wang L, Chen B, Li Z, Yao X, Liu M, Rong W, Wu F, Lin S, Liu Y, Zheng Y, Li Y, Wang W, Wu J

OncoTargets and Therapy 2019, 12:1237-1247

Published Date: 15 February 2019

Knockdown of EIF3C promotes human U-2OS cells apoptosis through increased CAS P3/7 and Chk1/2 by upregulating SAPK/JNK

Gao WL, Hu Y, Zhang ZQ, Du GW, Yin L, Yin ZS

OncoTargets and Therapy 2019, 12:1225-1235

Published Date: 14 February 2019

Combined silencing of VEGF-A and angiopoietin-2, a more effective way to inhibit the Ishikawa endometrial cancer cell line

Xu X, Yan Y, Xun Q, Shi J, Kong X, Wu J, Zhou H

OncoTargets and Therapy 2019, 12:1215-1223

Published Date: 14 February 2019

PNUTS mediates ionizing radiation-induced CNE-2 nasopharyngeal carcinoma cell migration, invasion, and epithelial–mesenchymal transition via the PI3K/AKT signaling pathway

Yu D, An X, Fan W, Wang X, He Y, Li B

OncoTargets and Therapy 2019, 12:1205-1214

Published Date: 15 February 2019

Metabolic reprogramming results in abnormal glycolysis in gastric cancer: a review

Liu Y, Zhang Z, Wang J, Chen C, Tang X, Zhu J, Liu J

OncoTargets and Therapy 2019, 12:1195-1204

Published Date: 13 February 2019

Dicerandrol B: a natural xanthone dimer induces apoptosis in cervical cancer HeLa cells through the endoplasmic reticulum stress and mitochondrial damage

Gao DD, Guo ZM, Wang JB, Hu GF, Su YQ, Chen LJ, Lv QW, Yu HM, Qin JC, Xu W

OncoTargets and Therapy 2019, 12:1185-1193

Published Date: 13 February 2019

Rapid and complete response to idelalisib in a case of Richter syndrome

Bagacean C, Zdrenghea M, Saad H, Berthou C, Renaudineau Y, Tempescul A

OncoTargets and Therapy 2019, 12:1181-1184

Published Date: 13 February 2019

Up-regulation of CKAP2L expression promotes lung adenocarcinoma invasion and is associated with poor prognosis

Xiong GS, Li LY, Chen XB, Song SN, Zhao YP, Cai WK, Peng JP

OncoTargets and Therapy 2019, 12:1171-1180

Published Date: 12 February 2019

High-intensity focused ultrasound enhances the effect of bufalin by inducing apoptosis in pancreatic cancer cells

Ning Z, Zhu Z, Wang H, Zhang C, Xu L, Zhuang L, Yan X, Wang D, Wang P, Meng Z

OncoTargets and Therapy 2019, 12:1161-1170

Published Date: 12 February 2019

Mst1-Hippo pathway triggers breast cancer apoptosis via inducing mitochondrial fragmentation in a manner dependent on JNK–Drp1 axis

Ouyang H, Zhou E, Wang H

OncoTargets and Therapy 2019, 12:1147-1159

Published Date: 11 February 2019

Epstein-Barr virus-encoded LMP1 regulated Pim1 kinase expression promotes nasopharyngeal carcinoma cells proliferation

Ding R, Yuan J, Jia Y, Liao X, Wang S, Shao Z, Feng M, Jie W, Shen Z

OncoTargets and Therapy 2019, 12:1137-1146

Published Date: 11 February 2019

Prognostic implications of MYBL2 in resected Chinese gastric adenocarcinoma patients

Jia YX, Gao YP, Li J, Chang ZW, Yan J, Qin YR

OncoTargets and Therapy 2019, 12:1129-1135

Published Date: 11 February 2019

Extracellular Hsp90α clinically correlates with tumor malignancy and promotes migration and invasion in esophageal squamous cell carcinoma

Wang X, An D, Wang X, Liu X, Li B

OncoTargets and Therapy 2019, 12:1119-1128

Published Date: 11 February 2019

Overexpression of shugoshin1 predicts a poor prognosis for prostate cancer and promotes metastasis by affecting epithelial–mesenchymal transition

Mu J, Fan L, Liu D, Zhu D

OncoTargets and Therapy 2019, 12:1111-1118

Published Date: 8 February 2019

Expression of Lin28 is correlated with prognosis and expression of HER-2 and steroid receptors in breast cancer

Xu C, Jin S, Huang L

OncoTargets and Therapy 2019, 12:1105-1110

Published Date: 8 February 2019

First-line treatment of women with advanced ovarian cancer: focus on bevacizumab

Marchetti C, Muzii L, Romito A, Benedetti Panici P

OncoTargets and Therapy 2019, 12:1095-1103

Published Date: 8 February 2019

Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma

Ollila TA, Sahin I, Olszewski AJ

OncoTargets and Therapy 2019, 12:1085-1094

Published Date: 7 February 2019

CHFR promotes the migration of human gastric cancer cells by inducing epithelial-to-mesenchymal transition in a HDAC1-dependent manner

Yang S, He F, Dai M, Pan J, Wang J, Ye B

OncoTargets and Therapy 2019, 12:1075-1084

Published Date: 7 February 2019

NCOA1–ALK: a novel ALK rearrangement in one lung adenocarcinoma patient responding to crizotinib treatment

Cao Q, Liu Z, Huang Y, Qi C, Yin X

OncoTargets and Therapy 2019, 12:1071-1074

Published Date: 7 February 2019

Long noncoding RNA GIHCG induces cancer progression and chemoresistance and indicates poor prognosis in colorectal cancer

Jiang X, Li Q, Zhang S, Song C, Zheng P

OncoTargets and Therapy 2019, 12:1059-1070

Published Date: 7 February 2019

Overexpressed long noncoding RNA TUG1 affects the cell cycle, proliferation, and apoptosis of pancreatic cancer partly through suppressing RND3 and MT2A

Hui B, Xu Y, Zhao B, Ji H, Ma Z, Xu S, He Z, Wang K, Lu J

OncoTargets and Therapy 2019, 12:1043-1057

Published Date: 5 February 2019

The lncRNA TUG1 promotes epithelial ovarian cancer cell proliferation and invasion via the WNT/β-catenin pathway [Retraction]

Liu S, Liu Y, Lu Q, Zhou X, Chen L, Liang W

OncoTargets and Therapy 2019, 12:1041-1042

Published Date: 4 February 2019

ZNF433 positively regulates the beta-catenin/TCF pathway in prostate cancer and enhances the tumorigenicity of cancer cells

Gu S, Hou P, Liu K, Niu X, Wei B, Mao F, Xu Z

OncoTargets and Therapy 2019, 12:1031-1039

Published Date: 1 February 2019

HIFU is safe, effective, and feasible in pancreatic cancer patients: a monocentric retrospective study among 523 patients

Ning Z, Xie J, Chen Q, Zhang C, Xu L, Song L, Meng Z

OncoTargets and Therapy 2019, 12:1021-1029

Published Date: 1 February 2019

Downregulated expression of RACK1 results in pancreatic cancer growth and metastasis

Zhang L, Lv Y, Rong Y, Chen W, Fang Y, Mao W, Lou W, Jin D, Xu X

OncoTargets and Therapy 2019, 12:1007-1020

Published Date: 1 February 2019

Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer

Xiong Y, Zhou L, Su Z, Song J, Sun Q, Liu SS, Xia Y, Wang Z, Lu D

OncoTargets and Therapy 2019, 12:993-1005

Published Date: 5 February 2019

Hypertension as a predictive biomarker in patients with advanced non-small-cell lung cancer treated with apatinib

Fang SC, Huang W, Zhang YM, Zhang HT, Xie WP

OncoTargets and Therapy 2019, 12:985-992

Published Date: 1 February 2019

miR-135a suppresses migration of gastric cancer cells by targeting TRAF5-mediated NF-κB activation

Xie Y, Li F, Li Z, Shi Z

OncoTargets and Therapy 2019, 12:975-984

Published Date: 1 February 2019

Efficacy and safety of targeted therapy for metastatic HER2-positive breast cancer in the first-line treatment: a Bayesian network meta-analysis

Feng F, Zhang T, Yin F, Liu C, Zhuang J, Qi L, Wang X, Li J, Wang L, Tian J, Sun C

OncoTargets and Therapy 2019, 12:959-974

Published Date: 31 January 2019

The coexistence of a Wilms’ tumor and renal cell carcinoma in children: a case report and review of the literature

Zou XP, Jiang YY, Liao Y, Dang YW, Chen G, Feng ZB, Ma Y

OncoTargets and Therapy 2019, 12:953-958

Published Date: 30 January 2019

The expression of special AT-rich binding protein 1 in cervical cancer and its clinical significance

Zhao L, Zheng Y, Ji Y, Zhang X

OncoTargets and Therapy 2019, 12:945-951

Published Date: 30 January 2019

Effects of combined inhibition of STAT3 and VEGFR2 pathways on the radiosensitivity of non-small-cell lung cancer cells

Hu C, Zhuang W, Qiao Y, Liu B, Liu L, Hui K, Jiang X

OncoTargets and Therapy 2019, 12:933-944

Published Date: 29 January 2019

Establishing a detection method for CCNY: a potentially significant clinical investigative marker in NSCLC patients

Ma L, Gu M, Teng Y, Li W

OncoTargets and Therapy 2019, 12:921-932

Published Date: 29 January 2019

microRNA-628 inhibits the proliferation of acute myeloid leukemia cells by directly targeting IGF-1R

Chen L, Jiang X, Chen H, Han Q, Liu C, Sun M

OncoTargets and Therapy 2019, 12:907-919

Published Date: 29 January 2019

Reversing platinum resistance in ovarian cancer multicellular spheroids by targeting Bcl-2

Yang Y, Li S, Sun Y, Zhang D, Zhao Z, Liu L

OncoTargets and Therapy 2019, 12:897-906

Published Date: 29 January 2019

Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation

Ji Y, Liu Y, Xue N, Du T, Wang L, Huang R, Li L, Yan C, Chen X

OncoTargets and Therapy 2019, 12:883-896

Published Date: 29 January 2019

Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1

Wang J, Li H, Xia C, Yang X, Dai B, Tao K, Dou K

OncoTargets and Therapy 2019, 12:869-882

Published Date: 29 January 2019

Efficacy and safety of nivolumab for metastatic biliary tract cancer

Gou M, Zhang Y, Si H, Dai G

OncoTargets and Therapy 2019, 12:861-867

Published Date: 25 January 2019

MiR–206 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting the MUC1 gene

Deng M, Qin Y, Chen X, Wang Q, Wang J

OncoTargets and Therapy 2019, 12:849-859

Published Date: 25 January 2019

miRNA-101-5p inhibits the growth and aggressiveness of NSCLC cells through targeting CXCL6

Chen Q, Liu D, Hu Z, Luo C, Zheng SL

OncoTargets and Therapy 2019, 12:835-848

Published Date: 25 January 2019

The inhibitive effect of sh-HIF1A-AS2 on the proliferation, invasion, and pathological damage of breast cancer via targeting miR-548c-3p through regulating HIF-1α/VEGF pathway in vitro and vivo

Guo X, Lee S, Cao P

OncoTargets and Therapy 2019, 12:825-834

Published Date: 24 January 2019

Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma

Wang L, Liu Y, Yu G

OncoTargets and Therapy 2019, 12:815-823

Published Date: 24 January 2019

lncRNA small nucleolar RNA host gene 20 predicts poor prognosis in glioma and promotes cell proliferation by silencing P21

Li XS, Shen FZ, Huang LY, Hui L, Liu RH, Ma YJ, Jin BZ

OncoTargets and Therapy 2019, 12:805-814

Published Date: 24 January 2019

MicroRNA-505 suppresses gastric cancer cell proliferation and invasion by directly targeting Polo-like kinase-1

Dang SC, Wang F, Qian XB, Abdul M, Naseer QA, Jin W, Hu R, Gu Q, Gu M

OncoTargets and Therapy 2019, 12:795-803

Published Date: 24 January 2019

G-protein-signaling modulator 2 expression and role in a CD133+ pancreatic cancer stem cell subset

Dang SC, Qian XB, Jin W, Cui L, Chen JX, Gu M

OncoTargets and Therapy 2019, 12:785-794

Published Date: 23 January 2019

Fenofibrate potentiates chemosensitivity to human breast cancer cells by modulating apoptosis via AKT/NF-κB pathway

Sun J, Zheng Z, Chen Q, Pan Y, Quan M, Dai Y

OncoTargets and Therapy 2019, 12:773-783

Published Date: 23 January 2019

MicroRNA-217 acts as a tumor suppressor and correlates with the chemoresistance of cervical carcinoma to cisplatin

Yin Z, Ren W

OncoTargets and Therapy 2019, 12:759-771

Published Date: 23 January 2019

Radiotherapy in advanced glottic laryngeal carcinoma in a patient with Wegener’s granulomatosis: how much radiation dose is needed?

Lazzari G, Briatico Vangosa A, De Cillis MA, Silvano G

OncoTargets and Therapy 2019, 12:753-757

Published Date: 23 January 2019

miR-124, a potential therapeutic target in colorectal cancer

Qin Z, Liu X

OncoTargets and Therapy 2019, 12:749-751

Published Date: 22 January 2019

Acquisition of T790M resistance mutation in a patient with advanced adenocarcinoma harboring uncommon EGFR mutations: a case report and literature review

Hakozaki T, Yomota M

OncoTargets and Therapy 2019, 12:745-748

Published Date: 22 January 2019

Comparison of neoadjuvant therapy and upfront surgery in resectable pancreatic cancer: a meta-analysis and systematic review

Ren X, Wei X, Ding Y, Qi F, Zhang Y, Hu X, Qin C, Li X

OncoTargets and Therapy 2019, 12:733-744

Published Date: 22 January 2019

Anticancer activity of 1, 25-(OH)2D3 against human breast cancer cell lines by targeting Ras/MEK/ERK pathway

Zheng W, Cao L, Ouyang L, Zhang Q, Duan B, Zhou W, Chen S, Peng W, Xie Y, Fan Q, Gong D

OncoTargets and Therapy 2019, 12:721-732

Published Date: 22 January 2019

Combining data from TCGA and GEO databases and reverse transcription quantitative PCR validation to identify gene prognostic markers in lung cancer

Liu X, Wang J, Chen M, Liu S, Yu X, Wen F

OncoTargets and Therapy 2019, 12:709-720

Published Date: 21 January 2019

LncRNA SNHG16 drives proliferation and invasion of papillary thyroid cancer through modulation of miR-497

Wen Q, Zhao L, Wang T, Lv N, Cheng X, Zhang G, Bai L

OncoTargets and Therapy 2019, 12:699-708

Published Date: 18 January 2019

Expression of NR1H3 in endometrial carcinoma and its effect on the proliferation of Ishikawa cells in vitro

Fang F, Li D, Zhao L, Li Y, Zhang T, Cui B

OncoTargets and Therapy 2019, 12:685-697

Published Date: 18 January 2019

Role of radiotherapy in the treatment of metastatic head and neck cancer

Ordoñez R, Otero A, Jerez I, Medina JA, Lupiañez-Pérez Y, Gomez-Millan J

OncoTargets and Therapy 2019, 12:677-683

Published Date: 18 January 2019

Comparing short-time outcomes of three-dimensional and two-dimensional totally laparoscopic surgery for colon cancer using overlapped delta-shaped anastomosis

Su H, Jin W, Wang P, Bao M, Wang X, Zhao C, Wang X, Zhou Z, Zhou H

OncoTargets and Therapy 2019, 12:669-675

Published Date: 18 January 2019

The lncRNA ZEB2-AS1 is upregulated in gastric cancer and affects cell proliferation and invasion via miR-143-5p/HIF-1α axis

Wu F, Gao H, Liu K, Gao B, Ren H, Li Z, Liu F

OncoTargets and Therapy 2019, 12:657-667

Published Date: 18 January 2019

Long non-coding RNA LINC00662 promotes proliferation and migration in oral squamous cell carcinoma

Xu D, Chen Y, Yuan C, Zhang S, Peng W

OncoTargets and Therapy 2019, 12:647-656

Published Date: 18 January 2019

Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies

Tan FH, Putoczki TL, Stylli SS, Luwor RB

OncoTargets and Therapy 2019, 12:635-645

Published Date: 18 January 2019

RAP80 expression in breast cancer and its relationship with apoptosis in breast cancer cells

Jin GH, Mao X, Qiao Z, Chen B, Jin F

OncoTargets and Therapy 2019, 12:625-634

Published Date: 18 January 2019

Ureteral metastasis of non-small-cell lung cancer: a case report

Ren F, Liu M, Xu X, Zhang H, Li X, Liu J, Chen J

OncoTargets and Therapy 2019, 12:619-623

Published Date: 15 January 2019

Pharmacological inhibition of USP7 promotes antitumor immunity and contributes to colon cancer therapy

Fu C, Zhu X, Xu P, Li Y

OncoTargets and Therapy 2019, 12:609-617

Published Date: 15 January 2019

miR-4262, low level of which predicts poor prognosis, targets proto-oncogene CD163 to suppress cell proliferation and invasion in gastric cancer

Zhang H, Jiang H, Zhang H, Liu J, Hu X, Chen L

OncoTargets and Therapy 2019, 12:599-607

Published Date: 15 January 2019

Scutellarin inhibits the metastasis and cisplatin resistance in glioma cells

Tang S, Gao Y, Hu W

OncoTargets and Therapy 2019, 12:587-598

Published Date: 15 January 2019

Effect of CD44st and HER2 expression on the postoperative prognosis of breast cancer patients

Chen DD, Ji JA, Yan HC, Huang GH, Fang XJ

OncoTargets and Therapy 2019, 12:577-585

Published Date: 15 January 2019

Comprehensive analysis of potential prognostic genes for the construction of a competing endogenous RNA regulatory network in hepatocellular carcinoma

Yue C, Ren Y, Ge H, Liang C, Xu Y, Li G, Wu J

OncoTargets and Therapy 2019, 12:561-576

Published Date: 14 January 2019

Review

Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies

Xue B, Zhao J, Feng P, Xing J, Wu H, Li Y

OncoTargets and Therapy 2019, 12:549-559

Published Date: 11 January 2019

Should we apply sorafenib in hepatocellular carcinoma patients with microvascular invasion after curative hepatectomy?

Huang Y, Zhang Z, Zhou Y, Yang J, Hu K, Wang Z

OncoTargets and Therapy 2019, 12:541-548

Published Date: 11 January 2019

Merkel cell carcinoma of the thigh: case report and review of the literature

Jiang W, Xu J, Wang R, Wang T, Shu Y, Liu L

OncoTargets and Therapy 2019, 12:535-540

Published Date: 11 January 2019

Clinical significance of miR-195 in hepatocellular carcinoma and its biological function in tumor progression

Chen X, Wang A

OncoTargets and Therapy 2019, 12:527-534

Published Date: 10 January 2019

Correlation between high-resolution computed tomography lung nodule characteristics and EGFR mutation in lung adenocarcinomas

Nie Y, Liu H, Tan X, Wang H, Li F, Li C, Han P, Lyv X, Xu X, Guo M

OncoTargets and Therapy 2019, 12:519-526

Published Date: 10 January 2019

Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling

Jiang Z, Cao Q, Dai G, Wang J, Liu C, Lv L, Pan J

OncoTargets and Therapy 2019, 12:509-518

Published Date: 9 January 2019

Long noncoding RNA UCA1 targets miR-582-5p and contributes to the progression and drug resistance of bladder cancer cells through ATG7-mediated autophagy inhibition

Wu J, Li W, Ning J, Yu W, Rao T, Cheng F

OncoTargets and Therapy 2019, 12:495-508

Published Date: 9 January 2019

Diagnostic significance of miR-210 as a potential tumor biomarker of human cancer detection: an updated pooled analysis of 30 articles

Feng S, He A, Wang D, Kang B

OncoTargets and Therapy 2019, 12:479-493

Published Date: 9 January 2019

The anthelmintic drug flubendazole induces cell apoptosis and inhibits NF-κB signaling in esophageal squamous cell carcinoma

Tao J, Zhao H, Xie X, Luo M, Gao Z, Sun H, Huang Z

OncoTargets and Therapy 2019, 12:471-478

Published Date: 9 January 2019

Diagnostic value of multiple tumor-associated autoantibodies in lung cancer

Zhang R, Ma L, Li W, Zhou S, Xu S

OncoTargets and Therapy 2019, 12:457-469

Published Date: 9 January 2019

Nodal staging score and adequacy of nodal staging

Chen H, Feng G

OncoTargets and Therapy 2019, 12:449-455

Published Date: 8 January 2019

Complete response with fluorouracil and irinotecan with a BRAFV600E and EGFR inhibitor in BRAF-mutated metastatic colorectal cancer: a case report

Wang Z, Dai WP, Zang YS

OncoTargets and Therapy 2019, 12:443-447

Published Date: 8 January 2019

miR-302 cluster inhibits angiogenesis and growth of K562 leukemia cells by targeting VEGFA

Cao J, Li L, Han X, Cheng H, Chen W, Qi K, Chen C, Wu Q, Niu M, Zeng L, Xu K

OncoTargets and Therapy 2019, 12:433-441

Published Date: 8 January 2019

lncRNA CASC9 regulates cell migration and invasion in hemangioma endothelial cells by targeting miR-125a-3p/Nrg1

Li X, Chen B, Chi D, Zhang Y, Jiang W

OncoTargets and Therapy 2019, 12:423-432

Published Date: 7 January 2019

Long noncoding RNA SNHG16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p

Ye J, Zhang R, Du X, Chai W, Zhou Q

OncoTargets and Therapy 2019, 12:415-422

Published Date: 4 January 2019

PLK1 as a potential prognostic marker of gastric cancer through MEK-ER K pathway on PDTX models [Corrigendum]

Dang SC, Fan YY, Cui L, Chen JX, Qu JG, Gu M

OncoTargets and Therapy 2019, 12:413-414

Published Date: 3 January 2019

rs187960998 polymorphism in miR-211 prevent development of human colon cancer by deregulation of 3’UTR in CHD5

Zhu L, Wang R, Zhang L, Zuo C, Zhang R, Zhao S

OncoTargets and Therapy 2019, 12:405-412

Published Date: 3 January 2019

TRIM28 activates autophagy and promotes cell proliferation in glioblastoma

Peng Y, Zhang M, Jiang Z, Jiang Y

OncoTargets and Therapy 2019, 12:397-404

Published Date: 3 January 2019

CART cell therapy for prostate cancer: status and promise

Pan J, Guo Z, Yang C, Mao L

OncoTargets and Therapy 2019, 12:391-395

Published Date: 3 January 2019

Targeted neoadjuvant therapy in the HER-2-positive breast cancer patients: a systematic review and meta-analysis

Ma W, Zhao F, Zhou C, Zhang Y, Zhao Y, Li N, Xie P

OncoTargets and Therapy 2019, 12:379-390

Published Date: 3 January 2019

The progression of HMGB1-induced autophagy in cancer biology

Xu T, Jiang L, Wang Z

OncoTargets and Therapy 2019, 12:365-377

Published Date: 31 December 2018

Serum cytoskeleton-associated protein 4 as a biomarker for the diagnosis of hepatocellular carcinoma

Wang Y, Yu W, He M, Huang Y, Wang M, Zhu J

OncoTargets and Therapy 2019, 12:359-364

Published Date: 31 December 2018

Comparison of the diagnostic performance of fluorescence in situ hybridization (FISH), nuclear matrix protein 22 (NMP22), and their combination model in bladder carcinoma detection: a systematic review and meta-analysis

Liang Q, Zhang G, Li W, Wang J, Sheng S

OncoTargets and Therapy 2019, 12:349-358

Published Date: 31 December 2018

Combination of TPF regimen and cinobufotalin inhibits proliferation and induces apoptosis in human hypopharyngeal and laryngeal squamous cell carcinoma cells

Shen X, Tao Y, Yang Y, Wang R, Fang J, Lian M

OncoTargets and Therapy 2019, 12:341-348

Published Date: 31 December 2018

Toward fully exploiting the therapeutic potential of marketed pharmaceuticals: the use of octreotide and chloroquine in oncology

Papanagnou P, Papadopoulos GE, Stivarou T, Pappas A

OncoTargets and Therapy 2019, 12:319-339

Published Date: 31 December 2018

MiR-6991-3p is identified as a novel suppressor in the expansion and activation of myeloid-derived suppressor cells in hepatoma-bearing mice

Sun JP, Ge QX, Ren Z, Sun XF, Xie SP

OncoTargets and Therapy 2019, 12:309-317

Published Date: 28 December 2018

Evaluating ivosidenib for the treatment of relapsed/refractory AML: design, development, and place in therapy

Nassereddine S, Lap CJ, Tabbara IA

OncoTargets and Therapy 2019, 12:303-308

Published Date: 28 December 2018

Contribution of FPR and TLR9 to hypoxia-induced chemoresistance of ovarian cancer cells

Cai Y, Huang J, Xing H, Li B, Li L, Wang X, Peng D, Chen J

OncoTargets and Therapy 2019, 12:291-301

Published Date: 28 December 2018

CD4+ CD25+ regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial–mesenchymal transition

Shi C, Chen Y, Chen Y, Yang Y, Bing W, Qi J

OncoTargets and Therapy 2019, 12:279-289

Published Date: 28 December 2018

Should S-1 be better than capecitabine for patients with advanced gastric cancer in Asia? A systematic review and meta-analysis

Ye Z, Chen J, Rao Y, Yang W

OncoTargets and Therapy 2019, 12:269-277

Published Date: 27 December 2018

Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

Guo Q, Liu Y, Zhao J, Wang J, Li Y, Pang Y, Chen J, Wang J

OncoTargets and Therapy 2019, 12:257-267

Published Date: 27 December 2018

Circ-DLG 1 promotes the proliferation of esophageal squamous cell carcinoma [Erratum]

Rong J, Wang Q, Zhang Y, Zhu D, Sun H, Tang W, Wang R, Shi W, Cao XF

OncoTargets and Therapy 2019, 12:255-256

Published Date: 27 December 2018

Upregulation of valosin-containing protein (VCP) is associated with poor prognosis and promotes tumor progression of orbital B-cell lymphoma

Zhu W, Li D, Xiao L

OncoTargets and Therapy 2019, 12:243-253

Published Date: 27 December 2018

DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells

Yang C, Li D, Bai Y, Song S, Yan P, Wu R, Zhang Y, Hu G, Lin C, Li X, Huang L

OncoTargets and Therapy 2019, 12:233-241

Published Date: 28 December 2018

The use of regorafenib for patients with refractory metastatic colorectal cancer in clinical practice

Yoon SE, Lee SJ, Lee J, Park SH, Park JO, Lim HY, Kang WK, Park YS, Kim ST

OncoTargets and Therapy 2019, 12:225-231

Published Date: 24 December 2018

CUX2 functions as an oncogene in papillary thyroid cancer

Sun Y, Ye D, Li Y, Chen E, Hao R, Cai Y, Wang Q, Wang O, Zhang X

OncoTargets and Therapy 2019, 12:217-224

Published Date: 24 December 2018

miR-125a restrains cell migration and invasion by targeting STAT3 in gastric cancer cells

Yang L, Zhang S, Guo K, Huang H, Qi S, Yao J, Zhang Z

OncoTargets and Therapy 2019, 12:205-215

Published Date: 24 December 2018

Critical factors in chimeric antigen receptor-modified T-cell (CAR-T) therapy for solid tumors

Yan LL, Liu BN

OncoTargets and Therapy 2019, 12:193-204

Published Date: 24 December 2018

The diagnostic accuracy of liquid exosomes for lung cancer detection: a meta-analysis

Song Z, Wang S, Liu Y

OncoTargets and Therapy 2019, 12:181-192

Published Date: 24 December 2018

LncRNA SNHG5 promotes growth and invasion in melanoma by regulating the miR-26a-5p/TRPC3 pathway

Gao J, Zeng K, Liu Y, Gao L, Liu L

OncoTargets and Therapy 2019, 12:169-179

Published Date: 24 December 2018

Analysis of long non-coding RNAs in glioblastoma for prognosis prediction using weighted gene co-expression network analysis, Cox regression, and L1-LASSO penalization

Liang R, Zhi YQ, Zheng G, Zhang B, Zhu H, Wang M

OncoTargets and Therapy 2019, 12:157-168

Published Date: 21 December 2018

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro

Hu S, Xu L, Li L, Luo D, Zhao H, Li D, Peng B

OncoTargets and Therapy 2019, 12:147-156

Published Date: 21 December 2018

Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression

Guo L, Gu J, Hou S, Liu D, Zhou M, Hua T, Zhang J, Ge Z, Xu J

OncoTargets and Therapy 2019, 12:135-146

Published Date: 21 December 2018

RASSF1A promoter methylation correlates development, progression, and poor cancer-specific survival of renal cell carcinoma: trial sequential analysis

Zhuang Q, Chen Z, Shen J, Fan M, Xue D, Lu H, Xu R, He X

OncoTargets and Therapy 2019, 12:119-134

Published Date: 20 December 2018

Individualized treatment for a case of recurrent ovarian ependymoma

Yuan Z, Yu M, Chen Y

OncoTargets and Therapy 2019, 12:113-117

Published Date: 20 December 2018

Long noncoding RNA SNHG15 serves as an oncogene and predicts poor prognosis in epithelial ovarian cancer

Qu C, Dai C, Guo Y, Qin R, Liu J

OncoTargets and Therapy 2019, 12:101-111

Published Date: 19 December 2018

Tanshinol inhibits the growth, migration and invasion of hepatocellular carcinoma cells via regulating the PI3K-AKT signaling pathway

Zhu P, Liu Z, Zhou J, Chen Y

OncoTargets and Therapy 2019, 12:87-99

Published Date: 19 December 2018

Long noncoding RNA LINC01296 promotes cancer-cell proliferation and metastasis in urothelial carcinoma of the bladder

Wang X, Wang L, Gong Y, Liu Z, Qin Y, Chen J, Li N

OncoTargets and Therapy 2019, 12:75-85

Published Date: 19 December 2018

Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma

Cao JX, Lu Y

OncoTargets and Therapy 2019, 12:63-74

Published Date: 20 December 2018

Use of anlotinib in intra-abdominal desmoplastic small round cell tumors: a case report and literature review

Chen HM, Feng G

OncoTargets and Therapy 2019, 12:57-61

Published Date: 18 December 2018

Newly emergent acquired EGFR exon 18 G724S mutation after resistance of a T790M specific EGFR inhibitor osimertinib in non-small-cell lung cancer: a case report

Zhang Y, He B, Zhou D, Li M, Hu C

OncoTargets and Therapy 2019, 12:51-56

Published Date: 18 December 2018

MicroRNA-562 negatively regulated c-MET/AKT pathway in the growth of glioblastoma cells

Nie X, Su Z, Yan R, Yan A, Qiu S, Zhou Y

OncoTargets and Therapy 2019, 12:41-49

Published Date: 21 December 2018

Upregulation of syncytin-1 promotes invasion and metastasis by activating epithelial-mesenchymal transition-related pathway in endometrial carcinoma

Liu C, Xu J, Wen F, Yang F, Li X, Geng D, Li L, Chen J, Zheng J

OncoTargets and Therapy 2019, 12:31-40

Published Date: 17 December 2018

Methotrexate-induced apoptosis in human ovarian adenocarcinoma SKOV-3 cells via ROS-mediated bax/bcl-2-cyt-c release cascading

AlBasher G, AlKahtane AA, Alarifi S, Ali D, Alessia MS, Almeer RS, Abdel-Daim MM, Al-Sultan NK, Al-Qahtani AA, Ali H, Alkahtani S

OncoTargets and Therapy 2019, 12:21-30

Published Date: 17 December 2018

Ceritinib for an anaplastic lymphoma kinase rearrangement-positive patient previously treated with alectinib with poor performance status

Kitadai R, Okuma Y, Kawai S

OncoTargets and Therapy 2019, 12:15-19

Published Date: 17 December 2018

Pain predicts overall survival in men with metastatic castration-resistant prostate cancer treated with radium-223

Roviello G, Gallicchio R, Bozza G, Rodriquenz MG, Aieta M, Storto G

OncoTargets and Therapy 2019, 12:9-13

Published Date: 17 December 2018

Upregulation of circulating miR130a is correlated with development of Barrett’s esophagus and esophageal adenocarcinoma

Wang L, Ji F, Liu G, Wang W, Li Z, Yue Y, Wang Z

OncoTargets and Therapy 2019, 12:1-7

Published Date: 17 December 2018

Next-generation sequencing of circulating tumor DNA for detection of gene mutations in lung cancer: implications for precision treatment

Lai J, Du B, Wang Y, Wu R, Yu Z

OncoTargets and Therapy 2018, 11:9111-9116

Published Date: 14 December 2018

Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer

Qiu J, Lin X, Zheng T, Tang X, Hua K

OncoTargets and Therapy 2018, 11:9101-9110

Published Date: 14 December 2018

miRNA-30c can be used as a target in the diagnosis and treatment of osteosarcoma

Sun R, Muheremu A, Hu Y

OncoTargets and Therapy 2018, 11:9091-9099

Published Date: 14 December 2018

Encorafenib/binimetinib for the treatment of BRAF-mutant advanced, unresectable, or metastatic melanoma: design, development, and potential place in therapy

Sun J, Zager JS, Eroglu Z

OncoTargets and Therapy 2018, 11:9081-9089

Published Date: 14 December 2018

Risk factors for lymph node metastasis and the impact of adjuvant chemotherapy on ductal carcinoma in situ with microinvasion: a population-based study

Chen C, Huang S, Huang A, Jia Y, Wang J, Zhang Z, Mao M, Wang L, Zhou J

OncoTargets and Therapy 2018, 11:9071-9080

Published Date: 13 December 2018

The effect of additional chemotherapy on high-risk prostate cancer: a systematic review and meta-analysis

Chen J, Zhang X, Sun G, Zhao J, Liu J, Zhao P, Dai J, Shen P, Zeng H

OncoTargets and Therapy 2018, 11:9061-9070

Published Date: 13 December 2018

Early and late outcomes of bevacizumab plus chemotherapy versus chemotherapy alone as a neoadjuvant treatment in HER2-negative nonmetastatic breast cancer: a meta-analysis of randomized controlled trials

Wei J, Luo Y, Fu D

OncoTargets and Therapy 2018, 11:9049-9059

Published Date: 12 December 2018

Curative effectiveness and safety of osimertinib in the treatment for non-small-cell lung cancer: a meta-analysis of the experimental evidence

Chen P, Chen F, Lei J, Zhou B

OncoTargets and Therapy 2018, 11:9033-9047

Published Date: 12 December 2018

Pseudomyxoma extraperitonei in horseshoe kidney masquerading as renal hilar tumor: a case report

Wang X, Gao X, Wang L, Dai Z, Fan B, Cui H, Liu Z

OncoTargets and Therapy 2018, 11:9027-9032

Published Date: 12 December 2018

microRNA-769 is downregulated in colorectal cancer and inhibits cancer progression by directly targeting cyclin-dependent kinase 1

Wang L, Xu M, Lu P, Zhou F

OncoTargets and Therapy 2018, 11:9013-9025

Published Date: 12 December 2018

A primary retroperitoneal anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with tumor thrombosis

Li J, Tian X, Wang M, Liu W, Guo X, Wang K, Nong L, Wang W, Yang Y

OncoTargets and Therapy 2018, 11:9007-9011

Published Date: 12 December 2018

Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl-2 axis

Zhao H, Han L, Jian Y, Ma Y, Yan W, Chen X, Xu H, Li L

OncoTargets and Therapy 2018, 11:8995-9006

Published Date: 11 December 2018

c.1439delA frameshift deletion mutation in familial adenomatous polyposis

Ma DJ, Wang BS, Yue JB, Li ZJ, Sun YL

OncoTargets and Therapy 2018, 11:8987-8993

Published Date: 11 December 2018

Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells

Li X, Zhu G, Yao X, Wang N, Hu R, Kong Q, Zhou D, Long L, Cai J, Zhou W

OncoTargets and Therapy 2018, 11:8977-8985

Published Date: 11 December 2018

miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1

Yao R, Zheng H, Wu L, Cai P

OncoTargets and Therapy 2018, 11:8965-8976

Published Date: 11 December 2018

MIIP is downregulated in gastric cancer and its forced expression inhibits proliferation and invasion of gastric cancer cells in vitro and in vivo

Sun D, Wang Y, Jiang S, Wang G, Xin Y

OncoTargets and Therapy 2018, 11:8951-8964

Published Date: 11 December 2018

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

De Carlo E, Schiappacassi M, Urbani M, Doliana R, Baldassarre G, Da Ros V, Santarossa S, Chimienti E, Berto E, Fratino L, Bearz A

OncoTargets and Therapy 2018, 11:8945-8950

Published Date: 10 December 2018

A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1 [Corrigendum]

Zhao XZ, Wu XH

OncoTargets and Therapy 2018, 11:8943-8944

Published Date: 10 December 2018

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms

Ludmir EB, Gutschenritter T, Pinnix CC, Gunther JR, Nastoupil LJ, Khoury JD, Medeiros LJ, Dabaja BS, Milgrom SA

OncoTargets and Therapy 2018, 11:8937-8942

Published Date: 10 December 2018

Osteopontin versus alpha-fetoprotein as a diagnostic marker for hepatocellular carcinoma: a meta-analysis

Sun TT, Tang YR, Sun DW, Bu Q, Li P

OncoTargets and Therapy 2018, 11:8925-8935

Published Date: 10 December 2018

The potential functions of FAM46C in oral squamous cell carcinoma

Zhuang X, Lu M

OncoTargets and Therapy 2018, 11:8915-8923

Published Date: 10 December 2018

Good local tumor control but lethal hemorrhage after apatinib treatment for intractable squamous carcinoma of the floor of the mouth: a case report

Zhu X, Liu M, Lv J, Guo L, Li C, Dong L, Liu B

OncoTargets and Therapy 2018, 11:8909-8913

Published Date: 7 December 2018

Drug–target–disease network analysis of gene–phenotype connectivity for genistein in ovarian cancer

Zhang C, Yang F, Ni S, Teng W, Ning Y

OncoTargets and Therapy 2018, 11:8901-8908

Published Date: 10 December 2018

Predictive value of positron emission tomography for the prognosis of molecularly targeted therapy in solid tumors

Xie X, Chen H, Yang H, Lin H, Zhou S, Shen R, Lu C, Ling L, Lin W, Liao Z

OncoTargets and Therapy 2018, 11:8885-8899

Published Date: 7 December 2018

Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/β-catenin pathway

Tang Z, Cai H, Wang R, Cui Y

OncoTargets and Therapy 2018, 11:8875-8883

Published Date: 7 December 2018

miRNA-19 promotes non-small-cell lung cancer cell proliferation via inhibiting CBX7 expression

Peng X, Guan L, Gao B

OncoTargets and Therapy 2018, 11:8865-8874

Published Date: 7 December 2018

Overexpressing lncRNA SNHG16 inhibited HCC proliferation and chemoresistance by functionally sponging hsa-miR-93

Xu F, Zha G, Wu Y, Cai W, Ao J

OncoTargets and Therapy 2018, 11:8855-8863

Published Date: 7 December 2018

Transcatheter hepatic arterial chemoembolization plus cinobufotalin injection adjuvant therapy for advanced hepatocellular carcinoma: a meta-analysis of 27 trials involving 2,079 patients

Guo N, Miao YY, Sun MZ

OncoTargets and Therapy 2018, 11:8835-8853

Published Date: 7 December 2018

Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells

Pérez-Cárdenas E, Taja-Chayeb L, Trejo-Becerril C, Chanona-Vilchis J, Chávez-Blanco A, Domínguez-Gómez G, Langley E, García-Carrancá A, Dueñas-González A

OncoTargets and Therapy 2018, 11:8823-8833

Published Date: 7 December 2018

TSPAN7 promotes the migration and proliferation of lung cancer cells via epithelial-to-mesenchymal transition

Wang X, Lin M, Zhao J, Zhu S, Xu M, Zhou X

OncoTargets and Therapy 2018, 11:8815-8822

Published Date: 13 December 2018

TRIM37 promotes cell invasion and metastasis by regulating SIP1-mediated epithelial–mesenchymal transition in gastric cancer

Chen D, You X, Pan Y, Liu Q, Cao G

OncoTargets and Therapy 2018, 11:8803-8813

Published Date: 10 December 2018

MicroRNA-486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells

Feng L, Jing L, Han J, Wang G, Liu Y, Zhang X, Wang Y, Wang F, Ma H, Liu Y

OncoTargets and Therapy 2018, 11:8791-8801

Published Date: 6 December 2018

PIWI-like protein 1 upregulation promotes gastric cancer invasion and metastasis

Gao CL, Sun R, Li DH, Gong F

OncoTargets and Therapy 2018, 11:8783-8789

Published Date: 6 December 2018

miR-1 inhibits the proliferation of breast cancer stem cells by targeting EVI-1

Wu L, Wang T, He D, Li X, Jiang Y

OncoTargets and Therapy 2018, 11:8773-8781

Published Date: 6 December 2018

SFRP5 inhibits the migration and invasion of melanoma cells through Wnt signaling pathway

Chen Y, Zou D, Wang N, Tan T, Liu Y, Zhao Q, Pu Y, Thapa RJ, Chen J

OncoTargets and Therapy 2018, 11:8761-8772

Published Date: 6 December 2018

Inhibition of XIAP increases carboplatin sensitivity in ovarian cancer

Zhang Y, Huang F, Luo Q, Wu X, Liu Z, Chen H, Huang Y

OncoTargets and Therapy 2018, 11:8751-8759

Published Date: 5 December 2018

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion

Song S, Li D, Yang C, Yan P, Bai Y, Zhang Y, Hu G, Lin C, Li X

OncoTargets and Therapy 2018, 11:8741-8750

Published Date: 5 December 2018

MALAT1 promotes proliferation, migration, and invasion of MG63 cells by upregulation of TGIF2 via negatively regulating miR-129

Liu K, Zhang YG, Liu L, Yuan QL

OncoTargets and Therapy 2018, 11:8729-8740

Published Date: 4 December 2018

Pathological complete response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with unresectable BRAF V600E-mutant malignant melanoma of the gallbladder

Yu Z, Quiroz E, Shen Y, Jaiyesimi IA

OncoTargets and Therapy 2018, 11:8723-8728

Published Date: 4 December 2018

Development and validation of a prognostic signature for preoperative prediction of overall survival in gastric cancer patients

Zhu M, Wang Q, Luo Z, Liu K, Zhang Z

OncoTargets and Therapy 2018, 11:8711-8722

Published Date: 4 December 2018

Clinical benefit from afatinib in an advanced squamous cell lung carcinoma patient harboring HER2 S310Y mutation: a case report

Gao Y, Zheng AH, Zhu XM, Song J, Xue Q

OncoTargets and Therapy 2018, 11:8705-8710

Published Date: 5 December 2018

MiR-411 suppresses the development of bladder cancer by regulating ZnT1

Liu Y, Liu T, Jin H, Yin L, Yu H, Bi J

OncoTargets and Therapy 2018, 11:8695-8704

Published Date: 4 December 2018

Application of preoperative three-dimensional model design in radioactive particle implantation for advanced pancreatic cancer

Liu Y, Lyu S, Wang X, Wang Y

OncoTargets and Therapy 2018, 11:8685-8693

Published Date: 4 December 2018

Original Research

Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients

Feldheim J, Kessler AF, Schmitt D, Wilczek L, Linsenmann T, Dahlmann M, Monoranu CM, Ernestus RI, Hagemann C, Löhr M

OncoTargets and Therapy 2018, 11:8673-8684

Published Date: 4 December 2018

A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model

Park S, Kim D, Wu G, Jung H, Park JA, Kwon HJ, Lee Y

OncoTargets and Therapy 2018, 11:8655-8672

Published Date: 3 December 2018

miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3

Guo J, Liu Q, Li Z, Guo H, Bai C, Wang F

OncoTargets and Therapy 2018, 11:8643-8653

Published Date: 3 December 2018

Natural product pectolinarigenin inhibits proliferation, induces apoptosis, and causes G2/M phase arrest of HCC via PI3K/AKT/mTOR/ERK signaling pathway

Wu T, Dong X, Yu D, Shen Z, Yu J, Yan S

OncoTargets and Therapy 2018, 11:8633-8642

Published Date: 3 December 2018

Efficacy and safety of PD1/PDL1 blockades versus docetaxel in patients with pretreated advanced non-small-cell lung cancer: a meta-analysis

Liu J, Zhong Y, Peng S, Zhou X, Gan X

OncoTargets and Therapy 2018, 11:8623-8632

Published Date: 3 December 2018

Efficacy and safety of bevacizumab-based combination therapy for treatment of patients with metastatic colorectal cancer

Xu R, Xu C, Liu C, Cui C, Zhu J

OncoTargets and Therapy 2018, 11:8605-8621

Published Date: 4 December 2018

Intestinal metastasis from breast invasive ductal carcinoma after a long latency: case report and literature review

Liu M, Zhang L, Guo L, Lv J, Shi W, Liu B

OncoTargets and Therapy 2018, 11:8599-8603

Published Date: 3 December 2018

A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia

Vinhas R, Lourenço A, Santos S, Lemos M, Ribeiro P, Botelho Sousa A, Baptista PV, Fernandes AR

OncoTargets and Therapy 2018, 11:8589-8598

Published Date: 30 November 2018

Original Research

Afatinib versus gemcitabine/cisplatin for first-line treatment of Chinese patients with advanced non-small-cell lung cancer harboring EGFR mutations: subgroup analysis of the LUX-Lung 6 trial

Wu YL, Xu CR, Hu CP, Feng J, Lu S, Huang Y, Li W, Hou M, Shi JH, Märten A, Fan J, Peil B, Zhou C

OncoTargets and Therapy 2018, 11:8575-8587

Published Date: 30 November 2018

Original Research

Afatinib vs erlotinib for second-line treatment of Chinese patients with advanced squamous cell carcinoma of the lung

Lu S, Li W, Zhou C, Hu CP, Qin S, Cheng G, Feng J, Wang J, Cseh A, Peil B, Gibson N, Ehrnrooth E, Zhang L

OncoTargets and Therapy 2018, 11:8565-8573

Published Date: 30 November 2018

Local analgesic effect of a bioadhesive barrier-forming oral liquid in cancer patients with oral mucositis caused by chemotherapy and/or radiotherapy: a randomized multicenter, single-use, positive-controlled, open-label study

Cheng Y, Qin SK, Chen YP, Dong LH, Sun XD, Yu SY, Wu SK

OncoTargets and Therapy 2018, 11:8555-8564

Published Date: 30 November 2018

Vandetanib (ZD6474) induces antiangiogenesis through mTOR–HIF-1 alpha–VEGF signaling axis in breast cancer cells

Li L, Yu J, Jiao S, Wang W, Zhang F, Sun S

OncoTargets and Therapy 2018, 11:8543-8553

Published Date: 29 November 2018

A novel long-sustaining system of apatinib for long-term inhibition of the proliferation of hepatocellular carcinoma cells

Wang YL, Tang ZG

OncoTargets and Therapy 2018, 11:8529-8541

Published Date: 29 November 2018

Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release

Ma Y, Liu X, Ma Q, Liu Y

OncoTargets and Therapy 2018, 11:8517-8528

Published Date: 29 November 2018

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1α

Tang L, Wu J, Cai S, Huang Y, Zhang X, Fu W, Zhuang Q, Li J

OncoTargets and Therapy 2018, 11:8507-8515

Published Date: 29 November 2018

Elevated FAM3C promotes cell epithelial–mesenchymal transition and cell migration in gastric cancer

Shi M, Duan G, Nie S, Shen S, Zou X

OncoTargets and Therapy 2018, 11:8491-8505

Published Date: 5 December 2018

Upregulation of SOX18 in colorectal cancer cells promotes proliferation and correlates with colorectal cancer risk

Miao Z, Deng X, Shuai P, Zeng J

OncoTargets and Therapy 2018, 11:8481-8490

Published Date: 29 November 2018

Overexpression of Mst1 reduces gastric cancer cell viability by repressing the AMPK-Sirt3 pathway and activating mitochondrial fission

Yao S, Yan W

OncoTargets and Therapy 2018, 11:8465-8479

Published Date: 29 November 2018

Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells

Yang Y, Zhu F, Wang Q, Ding Y, Ying R, Zeng L

OncoTargets and Therapy 2018, 11:8455-8463

Published Date: 29 November 2018

MiR-21-5p promotes the progression of non-small-cell lung cancer by regulating the expression of SMAD7

Li X, Wu X

OncoTargets and Therapy 2018, 11:8445-8454

Published Date: 28 November 2018

XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer

Li Q, Ma R, Zhang M

OncoTargets and Therapy 2018, 11:8435-8444

Published Date: 28 November 2018

High expression of uPA related to p38MAPK in esophageal cancer indicates poor prognosis

Liu Q, Li W, Yang S, Liu Z

OncoTargets and Therapy 2018, 11:8427-8434

Published Date: 29 November 2018

Better efficacy of intrapleural infusion of bevacizumab with pemetrexed for malignant pleural effusion mediated from nonsquamous non-small cell lung cancer

Song X, Chen D, Guo J, Kong L, Wang H, Wang Z

OncoTargets and Therapy 2018, 11:8421-8426

Published Date: 27 November 2018

lncRNA FBXL19-AS1 regulates osteosarcoma cell proliferation, migration and invasion by sponging miR-346

Pan RS, He ZX, Ruan WY, Li S, Chen H, Chen ZY, Liu F, Tian XB, Nie YJ

OncoTargets and Therapy 2018, 11:8409-8420

Published Date: 29 November 2018

LncRNA ANCR promotes proliferation and radiation resistance of nasopharyngeal carcinoma by inhibiting PTEN expression

Ma X, Zhou J, Liu J, Wu G, Yu Y, Zhu H, Liu J

OncoTargets and Therapy 2018, 11:8399-8408

Published Date: 27 November 2018

A comparison of fulvestrant plus a targeted agent with fulvestrant alone in hormone receptor-positive advanced breast cancer that progressed on prior endocrine therapy: a meta-analysis

Xu L, Yan N, Li Z, Luo L, Wu X, Liu Q, Xu Y, Cao Y

OncoTargets and Therapy 2018, 11:8389-8398

Published Date: 27 November 2018

Prognostic roles of mRNA expression of peroxiredoxins in lung cancer

Chen L, Huang C, Yang X, Zhang Q, Chen F

OncoTargets and Therapy 2018, 11:8381-8388

Published Date: 27 November 2018

GDF11 restrains tumor growth by promoting apoptosis in pancreatic cancer

Liu Y, Shao L, Chen K, Wang Z, Wang J, Jing W, Hu M

OncoTargets and Therapy 2018, 11:8371-8379

Published Date: 27 November 2018

Is APC hypermethylation a diagnostic biomarker for bladder cancer? A meta-analysis

Han W, Wang Y, Fan J, Wang C

OncoTargets and Therapy 2018, 11:8359-8369

Published Date: 27 November 2018

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells [Corrigendum]

Pan B, Han H, Wu L, Xiong Y, Zhang J, Dong B, Yang Y, Chen J

OncoTargets and Therapy 2018, 11:8357-8358

Published Date: 26 November 2018

TGF-beta 1 levels are associated with lymphocyte percentages in patients with lung cancer treated with radiation therapy

Luo J, Hu S, Wei T, Sun J, Liu N, Wang J

OncoTargets and Therapy 2018, 11:8349-8355

Published Date: 26 November 2018

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma

Jiang Z, Zhai X, Shi B, Luo D, Jin B

OncoTargets and Therapy 2018, 11:8341-8348

Published Date: 23 November 2018

New developments in the treatment of basal cell carcinoma: update on current and emerging treatment options with a focus on vismodegib

Koelblinger P, Lang R

OncoTargets and Therapy 2018, 11:8327-8340

Published Date: 23 November 2018

Prognostic significance of mammary Paget’s disease in Chinese women: a 10 year, population-based, matched cohort study

Zhou H, Lu K, Zheng L, Guo L, Gao Y, Miao X, Chen Z, Wang X

OncoTargets and Therapy 2018, 11:8319-8326

Published Date: 23 November 2018

Associations between the NUDT15 R139C polymorphism and susceptibility to thiopurine-induced leukopenia in Asians: a meta-analysis

Liu Y, Meng Y, Wang L, Liu Z, Li J, Dong W

OncoTargets and Therapy 2018, 11:8309-8317

Published Date: 23 November 2018

Modified FOLFOX6 as a first-line treatment for patients with advanced gastric cancer with massive ascites or inadequate oral intake

Osumi H, Takahari D, Chin K, Ogura M, Ichimura T, Wakatsuki T, Suzuki T, Ota Y, Nakayama I, Ooki A, Suenaga M, Shinozaki E, Yamaguchi K

OncoTargets and Therapy 2018, 11:8301-8307

Published Date: 23 November 2018

Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability

Li M, Yang Y

OncoTargets and Therapy 2018, 11:8293-8299

Published Date: 22 November 2018

The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1

Gagat M, Hałas-Wiśniewska M, Zielińska W, Izdebska M, Grzanka D, Grzanka A

OncoTargets and Therapy 2018, 11:8275-8292

Published Date: 22 November 2018

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage [Corrigendum]

Liu WJ, Yin YB, Sun JY, Feng S, Ma JK, Fu XY, Hou YJ, Yang MF, Sun BL, Fan CD

OncoTargets and Therapy 2018, 11:8273-8274

Published Date: 22 November 2018

The return of gemtuzumab ozogamicin: a humanized anti-CD33 monoclonal antibody–drug conjugate for the treatment of newly diagnosed acute myeloid leukemia

Egan PC, Reagan JL

OncoTargets and Therapy 2018, 11:8265-8272

Published Date: 22 November 2018

Platelets enhance the ability of bone-marrow mesenchymal stem cells to promote cancer metastasis

Wang Q, Li Z, Sun L, Chen B, Zhao Y, Shen B, Zhu M, Zhao X, Xu C, Wang M, Xu W, Zhu W

OncoTargets and Therapy 2018, 11:8251-8263

Published Date: 21 November 2018

Clinical efficacy of immune checkpoint inhibitors in the treatment of unresectable advanced or recurrent gastric cancer: an evidence-based review of therapies

Togasaki K, Sukawa Y, Kanai T, Takaishi H

OncoTargets and Therapy 2018, 11:8239-8250

Published Date: 21 November 2018

Icotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression

Sun J, Jiang W, Tian D, Guo Q, Shen Z

OncoTargets and Therapy 2018, 11:8227-8237

Published Date: 21 November 2018

Cytoskeleton-associated protein 4 is a novel serodiagnostic marker for esophageal squamous-cell carcinoma

Chen L, You C, Jin X, Zhou L, Huang L, Wang Y

OncoTargets and Therapy 2018, 11:8221-8226

Published Date: 20 November 2018

Alcoholic liver disease and risk of cholangiocarcinoma: a systematic review and meta-analysis

Xiong J, Yin Z, Xu W, Shen Z, Li Y, Lu X

OncoTargets and Therapy 2018, 11:8211-8219

Published Date: 20 November 2018

Afatinib reverses ceritinib resistance (CR) in ALK/ROS1-positive non-small-cell lung cancer cell (NSCLC) via suppression of NRG1 pathway

Chen H, Zhang Q, Zhang Y, Jia B, Zhang B, Wang C

OncoTargets and Therapy 2018, 11:8201-8209

Published Date: 26 November 2018

Primary clear cell adenocarcinoma of the pancreas: a case report and literature update

Sun PJ, Yu YH, Cui XJ

OncoTargets and Therapy 2018, 11:8197-8200

Published Date: 16 November 2018

Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway

Jin YL, Xin LM, Zhou CC, Ren Y

OncoTargets and Therapy 2018, 11:8185-8195

Published Date: 16 November 2018

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion

Ye Y, Song Y, Zhuang J, Wang G, Ni J, Zhang S, Xia W

OncoTargets and Therapy 2018, 11:8175-8184

Published Date: 10 December 2018

E2F transcription factor 8 promotes cell proliferation via CCND1/p21 in esophageal squamous cell carcinoma

Chang H, Song J, Wu J, Zhang Y

OncoTargets and Therapy 2018, 11:8165-8173

Published Date: 15 November 2018

The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells

Jiang H, Fan JJ, Cheng L, Hu P, Liu RB

OncoTargets and Therapy 2018, 11:8153-8163

Published Date: 14 November 2018

Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer

Sheng ML, Dong ZH, Xie YP

OncoTargets and Therapy 2018, 11:8143-8151

Published Date: 14 November 2018

Potential role of Toll-like receptor 2 expression and polymorphisms in colon cancer susceptibility in the Saudi Arabian population

Semlali A, Parine NR, Al-Numair NS, Almutairi M, Hawsawi YM, Al Amri A, Aljebreen AM, Arafah M, Almadi MA, Azzam NA, Alharbi O, Alanazi MS

OncoTargets and Therapy 2018, 11:8127-8141

Published Date: 14 November 2018

In vitro and in vivo superior radiosensitizing effect of berbamine for head and neck squamous cell carcinoma

Zhu H, Ruan S, Jia F, Chu J, Zhu Y, Huang Y, Liu G

OncoTargets and Therapy 2018, 11:8117-8125

Published Date: 14 November 2018

Follicle-stimulating hormone inhibits cervical cancer via NF-κB pathway

Shi X, Qiu S, Zhuang W, Wang C, Zhang S, Yuan N, Yuan F, Qiao Y

OncoTargets and Therapy 2018, 11:8107-8115

Published Date: 14 November 2018

Lipocalin 2: a potential therapeutic target for breast cancer metastasis

Hu C, Yang K, Li M, Huang W, Zhang F, Wang H

OncoTargets and Therapy 2018, 11:8099-8106

Published Date: 13 November 2018

High expression of TFEB is associated with aggressive clinical features in colorectal cancer

Liang J, Jia X, Wang K, Zhao N

OncoTargets and Therapy 2018, 11:8089-8098

Published Date: 13 November 2018

Association of MLH1 single nucleotide polymorphisms with clinical outcomes of first-line irinotecan-based chemotherapy in colorectal cancer

Wang D, Zhang X, Zhang Y, Wu Y, Guan X, Zhu W, Wang M, Qi C, Shen B

OncoTargets and Therapy 2018, 11:8083-8088

Published Date: 13 November 2018

Expression of CLIC1 as a potential biomarker for oral squamous cell carcinoma: a preliminary study

Xu Y, Xu J, Feng J, Li J, Jiang C, Li X, Zou S, Wang Q, Li Y

OncoTargets and Therapy 2018, 11:8073-8081

Published Date: 12 November 2018

Celecoxib suppresses cutaneous squamous-cell carcinoma cell migration via inhibition of SDF1-induced endocytosis of CXCR4

Gong T, Yu Y, Yang B, Lin M, Huang JW, Cheng B, Ji C

OncoTargets and Therapy 2018, 11:8063-8071

Published Date: 12 November 2018

Clinicopathological and prognostic significance of circulating tumor cells in patients with esophageal cancer: a meta-analysis

Hou J, Zou K, Yang C, Leng X, Xu Y

OncoTargets and Therapy 2018, 11:8053-8061

Published Date: 12 November 2018

Potential clinical application of lncRNAs in non-small cell lung cancer

Lu T, Wang Y, Chen D, Liu J, Jiao W

OncoTargets and Therapy 2018, 11:8045-8052

Published Date: 13 November 2018

Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells

Mu M, Li Y, Zhan Y, Li X, Zhang B

OncoTargets and Therapy 2018, 11:8033-8044

Published Date: 13 November 2018

miR-517a promotes Warburg effect in HCC by directly targeting FBP1

Zhang D, Li Z, Li T, Luo D, Feng X, Liu Y, Huang J

OncoTargets and Therapy 2018, 11:8025-8032

Published Date: 13 November 2018

Patterns of regional nodal relapse after D2 lymphadenectomy in gastric cancer: rethinking the target volume

Yang W, Zhou M, Hu R, Li G, Wang Y, Shen L, Liang L, Yang J, Zhang Z

OncoTargets and Therapy 2018, 11:8015-8024

Published Date: 12 November 2018

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6 [Erratum]

Chen C, Zhang Z, Li J, Sun Y

OncoTargets and Therapy 2018, 11:8013-8014

Published Date: 12 November 2018

Long noncoding RNA H19 mediated the chemosensitivity of breast cancer cells via Wnt pathway and EMT process

Gao H, Hao G, Sun Y, Li L, Wang Y

OncoTargets and Therapy 2018, 11:8001-8012

Published Date: 9 November 2018

Original Research

Lupeol inhibits growth and migration in two human colorectal cancer cell lines by suppression of Wnt–β-catenin pathway

Wang YH, Hong D, Qian YQ, Tu XZ, Wang KK, Yang XH, Shao SJ, Kong XL, Lou ZF, Jin LJ

OncoTargets and Therapy 2018, 11:7987-7999

Published Date: 9 November 2018

The prognostic roles of mRNAs of the exosomes derived from bone marrow stromal cells in common malignancies: a bioinformatic study

Zhao F, Yu YQ

OncoTargets and Therapy 2018, 11:7979-7986

Published Date: 12 November 2018

miR-185 suppresses progression of Ewing’s sarcoma via inhibiting the PI3K/AKT and Wnt/β-catenin pathways

Zhang S, Li D, Jiao G, Wang H, Yan T

OncoTargets and Therapy 2018, 11:7967-7977

Published Date: 9 November 2018

lncRNA differentiation antagonizing nonprotein coding RNA overexpression accelerates progression and indicates poor prognosis in pancreatic ductal adenocarcinoma

Chen L, Liu J, Tang T, Zhang Y, Liu M, Xu L, Zhang J

OncoTargets and Therapy 2018, 11:7955-7965

Published Date: 9 November 2018

Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell carcinoma treated with supracricoid partial laryngectomy or total laryngectomy

Xia X, Zhu YY, Diao WW, Zhu XL, Shi XH, Li WY, Gao ZQ, Li GJ, Chen XM

OncoTargets and Therapy 2018, 11:7947-7953

Published Date: 9 November 2018

TRIM37 targets AKT in the growth of lung cancer cells

Dong SM, Pang XQ, Sun HJ, Yuan CL, Mu CY, Zheng S

OncoTargets and Therapy 2018, 11:7935-7945

Published Date: 8 November 2018

MicroRNA-18a promotes hepatocellular carcinoma proliferation, migration, and invasion by targeting Bcl2L10

Wang X, Lu J, Cao J, Ma B, Gao C, Qi F

OncoTargets and Therapy 2018, 11:7919-7934

Published Date: 9 November 2018

Clinical evaluation of vascular normalization induced by recombinant human endostatin in nasopharyngeal carcinoma via dynamic contrast-enhanced ultrasonography

Yang Z, Kang M, Zhu S, Huang J, Li X, Wang R

OncoTargets and Therapy 2018, 11:7909-7917

Published Date: 8 November 2018

Therapeutic strategies of melatonin in cancer patients: a systematic review and meta-analysis

Wang Y, Wang P, Zheng X, Du X

OncoTargets and Therapy 2018, 11:7895-7908

Published Date: 8 November 2018

Transcatheter hepatic arterial infusion chemotherapy vs sorafenib in the treatment of patients with hepatocellular carcinoma of Barcelona Clinic Liver Cancer stage C: a meta-analysis of Asian population

Ni JY, Liu SS, Sun HL, Wang WD, Zhong ZL, Hou SN, Chen YT, Xu LF

OncoTargets and Therapy 2018, 11:7883-7894

Published Date: 6 November 2018

OCT4, SOX2, and NAN OG positive expression correlates with poor differentiation, advanced disease stages, and worse overall survival in HER2+ breast cancer patients

Yang F, Zhang J, Yang H

OncoTargets and Therapy 2018, 11:7873-7881

Published Date: 6 November 2018

Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro

Jiang T, Zhou ML, Fan J

OncoTargets and Therapy 2018, 11:7865-7872

Published Date: 6 November 2018

EZH2 contributes to 5-FU resistance in gastric cancer by epigenetically suppressing FBXO32 expression

Wang C, Li X, Zhang J, Ge Z, Chen H, Hu J

OncoTargets and Therapy 2018, 11:7853-7864

Published Date: 5 November 2018

TRIM32 overexpression improves chemoresistance through regulation of mitochondrial function in non-small-cell lung cancers

Du Y, Zhang W, Du B, Zang S, Wang X, Mao X, Hu Z

OncoTargets and Therapy 2018, 11:7841-7852

Published Date: 5 November 2018

Long noncoding RNA HOXD-AS1 in various cancers: a meta-analysis and TCGA data review

Zhang FH, Chen XW, Xi KH, Qiu ZQ, Wang YH, Gui Y, Hou Y, Chen KB, Zhang XB

OncoTargets and Therapy 2018, 11:7827-7840

Published Date: 5 November 2018

Intestinal metastasis from primary ROS1-positive lung adenocarcinoma cancer patients responding to crizotinib

Chen HF, Zhang QX, Zhu YC, Du KQ, Li XF, Wu LX, Wang WX, Xu CW

OncoTargets and Therapy 2018, 11:7821-7825

Published Date: 5 November 2018

Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer

Wu B, Qi R, Liu X, Qian L, Wu Z

OncoTargets and Therapy 2018, 11:7805-7820

Published Date: 5 November 2018

PTPRF as a novel tumor suppressor through deactivation of ERK1/2 signaling in gastric adenocarcinoma

Tian X, Yang C, Yang L, Sun Q, Liu N

OncoTargets and Therapy 2018, 11:7795-7803

Published Date: 2 November 2018

Huge borderline phyllodes breast tumor with repeated recurrences and progression toward more malignant phenotype: a case report and literature review

Wang Y, Zhang Y, Chen G, Liu F, Liu C, Xu T, Ma Z

OncoTargets and Therapy 2018, 11:7787-7793

Published Date: 2 November 2018

Original Research

Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK

Wang J, Li J, Cao N, Li Z, Han J, Li L

OncoTargets and Therapy 2018, 11:7777-7786

Published Date: 2 November 2018

Potential targets of TMEM176A in the growth of glioblastoma cells

Liu Z, An H, Song P, Wang D, Li S, Chen K, Pang Q

OncoTargets and Therapy 2018, 11:7763-7775

Published Date: 2 November 2018

Decreased expression of peroxiredoxin1 inhibits proliferation, invasion, and metastasis of ovarian cancer cell

Zheng MJ, Wang J, Wang HM, Gao LL, Li X, Zhang WC, Gou R, Guo Q, Nie X, Liu J, Lin B

OncoTargets and Therapy 2018, 11:7745-7761

Published Date: 2 November 2018

MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells

Meng D, Lei M, Han Y, Zhao D, Zhang X, Yang Y, Liu R

OncoTargets and Therapy 2018, 11:7733-7743

Published Date: 2 November 2018

Underexpression of INPPL1 is associated with aggressive clinicopathologic characteristics in papillary thyroid carcinoma

Zhou YL, Zheng C, Chen YT, Chen XM

OncoTargets and Therapy 2018, 11:7725-7731

Published Date: 1 November 2018

lncRNA PCAT6 promotes non-small cell lung cancer cell proliferation, migration and invasion through regulating miR-330-5p

Cui LH, Xu HR, Yang W, Yu LJ

OncoTargets and Therapy 2018, 11:7715-7724

Published Date: 1 November 2018

The clinical feasibility of flexible bronchoscopy interventional therapy in patients with central airway stenosis and respiratory failure caused by malignancy

Wang J, Yang Y, Zha W, Zhang X

OncoTargets and Therapy 2018, 11:7709-7714

Published Date: 1 November 2018

Low expression level of ASK1-interacting protein-1 correlated with tumor angiogenesis and poor survival in patients with esophageal squamous cell cancer

Sun D, Chen C, Hu W, Zhong C, Fan L, Song X, Gai Z

OncoTargets and Therapy 2018, 11:7699-7707

Published Date: 1 November 2018

A meta-analysis of nivolumab for the treatment of advanced non-small-cell lung cancer

Chen S, Hu B, Li H

OncoTargets and Therapy 2018, 11:7691-7697

Published Date: 31 October 2018

16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling

Chen YC, Huang BM, Lee WC, Chen YC

OncoTargets and Therapy 2018, 11:7679-7690

Published Date: 31 October 2018

Cytotoxic effect of Drimia maritima bulb extract and induction of mitochondrial apoptotic signaling in human breast cancer cells, MCF-7 and MDA-MB-468

Hamzeloo-Moghadam M, Aghaei M, Abdolmohammadi MH, Khalaj A, Fallahian F

OncoTargets and Therapy 2018, 11:7669-7677

Published Date: 31 October 2018

A systematic review and meta-analysis of gastrointestinal events associated with nonoperative therapies for neuroendocrine tumors

Wu Q, Chen B, Yan G, Yang Z, Xiong L, He J

OncoTargets and Therapy 2018, 11:7655-7668

Published Date: 31 October 2018

Acyl-CoA dehydrogenase long chain expression is associated with esophageal squamous cell carcinoma progression and poor prognosis

Yu DL, Li HW, Wang Y, Li CQ, You D, Jiang L, Song YP, Li XH

OncoTargets and Therapy 2018, 11:7643-7653

Published Date: 31 October 2018

Clinicopathological analysis of PD-L2 expression in colorectal cancer

Guo PD, Sun ZW, Lai HJ, Yang J, Wu PP, Guo YD, Sun J

OncoTargets and Therapy 2018, 11:7635-7642

Published Date: 1 November 2018

Significance of PYK2 level as a prognosis predictor in patients with colon adenocarcinoma after surgical resection

Liu S, Chen L, Xu Y

OncoTargets and Therapy 2018, 11:7625-7634

Published Date: 31 October 2018

SIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling

Ouyang L, Yi L, Li J, Yi S, Li S, Liu P, Yang X

OncoTargets and Therapy 2018, 11:7613-7624

Published Date: 1 November 2018

Protein tyrosine phosphatase L1 inhibits high-grade serous ovarian carcinoma progression by targeting IκBα

Wang Y, Li M, Huang T, Li J

OncoTargets and Therapy 2018, 11:7603-7612

Published Date: 30 October 2018

Knockdown of immature colon carcinoma transcript-I inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest [Expression of concern]

Xie R, Zhang Y, Shen C, Cao X, Gu S, Che X

OncoTargets and Therapy 2018, 11:7601-7602

Published Date: 30 October 2018

RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma

Yu Q, Zhang N, Jiang Y, Huang Y, Lian YY, Liu T, Li N, Guan G

OncoTargets and Therapy 2018, 11:7591-7600

Published Date: 2 November 2018

GATA3 is downregulated in osteosarcoma and facilitates EMT as well as migration through regulation of slug

Ma L, Xue W, Ma X

OncoTargets and Therapy 2018, 11:7579-7589

Published Date: 30 October 2018

ADAMTS8 targets ERK to suppress cell proliferation, invasion, and metastasis of hepatocellular carcinoma

Zhao XT, Yang CR, Wu JH, Nan YM

OncoTargets and Therapy 2018, 11:7569-7578

Published Date: 29 October 2018

Sirt3 enhances glioma cell viability by stabilizing Ku70–BAX interaction

Luo K, Huang W, Tang S

OncoTargets and Therapy 2018, 11:7559-7567

Published Date: 29 October 2018

Successful alternative treatment for relapsed adult acute lymphoblastic leukemia with dendritic cells-cytokine-induced killer cells combined with a rituximab-based regimen

Xiao X, Ye X, Xu C, Huang J

OncoTargets and Therapy 2018, 11:7555-7558

Published Date: 29 October 2018

Original Research

BMP-2 inhibits lung metastasis of osteosarcoma: an early investigation using an orthotopic model

Xiong Q, Wang X, Wang L, Huang Y, Tian X, Fan Y, Lin CY

OncoTargets and Therapy 2018, 11:7543-7553

Published Date: 29 October 2018

Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis

Weng YM, Peng M, Hu MX, Yao Y, Song QB

OncoTargets and Therapy 2018, 11:7529-7542

Published Date: 30 October 2018

The impact of immunosenescence on the efficacy of immune checkpoint inhibitors in melanoma patients: a meta-analysis

Li P, Yang X, Feng Y, Wu L, Ma W, Ding G, Wei Y, Sun L

OncoTargets and Therapy 2018, 11:7521-7527

Published Date: 26 October 2018

Re-biopsy status among Chinese non-small-cell lung cancer patients who progressed after icotinib therapy

Wang H, Zhang L, Si X, Zhang X, Wang M

OncoTargets and Therapy 2018, 11:7513-7519

Published Date: 26 October 2018

miR-23b-3p and miR-130a-5p affect cell growth, migration and invasion by targeting CB1R via the Wnt/β-catenin signaling pathway in gastric carcinoma

Xian X, Tang L, Wu C, Huang L

OncoTargets and Therapy 2018, 11:7503-7512

Published Date: 25 October 2018

FAM129B promoted tumor invasion and proliferation via facilitating the phosphorylation of FAK signaling and associated with adverse clinical outcome of non-small cell lung cancer patients

Zhou X, Yang F, Zhang Q, Miao Y, Hu X, Li A, Hou G, Wang Q, Kang J

OncoTargets and Therapy 2018, 11:7493-7501

Published Date: 25 October 2018

Long noncoding RNA UCA1 promotes the proliferation, invasion, and migration of nasopharyngeal carcinoma cells via modulation of miR-145

Wu J, Du M, Zhang Q, Zhang W, Fan Y, Yin L, Fei Q, Jiang X, Chen W, Zhu H, Yan P, He X, Bian X

OncoTargets and Therapy 2018, 11:7483-7492

Published Date: 25 October 2018

Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis

Li L, Cao Y, Zhou H, Li Y, He B, Zhou X, Nie Z, Liang L, Liu Y, Ye L

OncoTargets and Therapy 2018, 11:7471-7481

Published Date: 26 October 2018

Original Research

The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China

Liu Y, Qian L, Yang J, Huang H, Feng J, Li X, Bian T, Ke H, Liu J, Zhang J

OncoTargets and Therapy 2018, 11:7459-7469

Published Date: 25 October 2018

ARHGAP30 suppressed lung cancer cell proliferation, migration, and invasion through inhibition of the Wnt/β-catenin signaling pathway

Mao X, Tong J

OncoTargets and Therapy 2018, 11:7447-7457

Published Date: 24 October 2018

Options of medical treatment and laryngeal function preservation in elderly patients with medial wall pyriform sinus cancer

Wang Q, Liu Y, Wu K, Zhao Y, Gao C, Tong B, Zhang M

OncoTargets and Therapy 2018, 11:7441-7446

Published Date: 1 November 2018

Regulation of cell proliferation and metastasis by microRNA-593-5p in human gastric cancer

Yu H, Wei W, Cao W, Zhan Z, Yan L, Wu K, Xie D, Cai B, Xie Y, Xiao Q

OncoTargets and Therapy 2018, 11:7429-7440

Published Date: 24 October 2018

Activated pulmonary tuberculosis in a patient with melanoma during PD-1 inhibition: a case report

He W, Zhang XM, Li WW, Kong C, Wang YY, Zhu LY, Xu RL, Deng GF, Zhang PZ

OncoTargets and Therapy 2018, 11:7423-7427

Published Date: 24 October 2018

Research progress on GP73 in malignant tumors

Liang R, Liu Z, Piao X, Zuo M, Zhang J, Liu Z, Li Y, Lin Y

OncoTargets and Therapy 2018, 11:7417-7421

Published Date: 24 October 2018

Comprehensive bioinformatics analysis identifies several potential diagnostic markers and potential roles of cyclin family members in lung adenocarcinoma

Gao LW, Wang GL

OncoTargets and Therapy 2018, 11:7407-7415

Published Date: 24 October 2018

Notch1 serves as a prognostic factor and regulates metastasis via regulating EGFR expression in hypopharyngeal squamous cell carcinoma

Tian J, Liu X, Liu X, Jing P, Sa N, Wang H, Xu W

OncoTargets and Therapy 2018, 11:7395-7405

Published Date: 24 October 2018

Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma

Cao S, Chen G, Yan L, Li L, Huang X

OncoTargets and Therapy 2018, 11:7385-7394

Published Date: 24 October 2018

Review

The efficacy and safety of immune checkpoint inhibitor combination therapy in lung cancer: a systematic review and meta-analysis

Peng M, Li X, Lei G, Weng YM, Hu MX, Song QB

OncoTargets and Therapy 2018, 11:7369-7383

Published Date: 24 October 2018

Review

Enzalutamide-resistant castration-resistant prostate cancer: challenges and solutions

Tucci M, Zichi C, Buttigliero C, Vignani F, Scagliotti GV, Di Maio M

OncoTargets and Therapy 2018, 11:7353-7368

Published Date: 24 October 2018

Iodine-125 seed implantation and allogenic natural killer cell immunotherapy for hepatocellular carcinoma after liver transplantation: a case report

Xie S, Wu Z, Zhou L, Liang Y, Wang X, Niu L, Xu K, Chen J, Zhang M

OncoTargets and Therapy 2018, 11:7345-7352

Published Date: 25 October 2018

Down-regulation of CXCL 11 inhibits colorectal cancer cell growth and epithelial-mesenchymal transition

Gao YJ, Liu DL, Li S, Yuan GF, Li L, Zhu HY, Cao GY

OncoTargets and Therapy 2018, 11:7333-7343

Published Date: 23 October 2018

Clinical characterization of ERBB2 exon 20 insertions and heterogeneity of outcomes responding to afatinib in Chinese lung cancer patients

Liu Z, Wu L, Cao J, Yang Z, Zhou C, Cao L, Wu H, Shen H, Jin M, Zhang Y, Mao X, Xiang J, Ma K, Li B, Zhang T, Hu Y

OncoTargets and Therapy 2018, 11:7323-7331

Published Date: 23 October 2018

Radioembolization versus chemoembolization for unresectable hepatocellular carcinoma: a meta-analysis of randomized trials

Casadei Gardini A, Tamburini E, Iñarrairaegui M, Frassineti GL, Sangro B

OncoTargets and Therapy 2018, 11:7315-7321

Published Date: 25 October 2018

MCL-1 inhibition in cancer treatment

Xiang W, Yang CY, Bai L

OncoTargets and Therapy 2018, 11:7301-7314

Published Date: 23 October 2018

Case report

Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer

Salman P, Panay S, Fernández R, Mahave M, Soza-Ried C

OncoTargets and Therapy 2018, 11:7295-7300

Published Date: 23 October 2018

Efficacy and safety analysis on dendritic cell-based vaccine-treated high-grade glioma patients: a systematic review and meta-analysis

Li C, Liu T, Zhou B, Zhou Y, Yu H, Sun Y

OncoTargets and Therapy 2018, 11:7277-7293

Published Date: 24 October 2018

Radiation therapy’s efficacy on tongue cancer: a population-based survival analysis

Zhu Y, Zhou C, He Q

OncoTargets and Therapy 2018, 11:7271-7276

Published Date: 23 October 2018

Thymosin α1 suppresses migration and invasion of PD-L1 high-expressing non-small-cell lung cancer cells via inhibition of STAT3–MMP2 signaling

Bo C, Wu Q, Zhao H, Li X, Zhou Q

OncoTargets and Therapy 2018, 11:7255-7270

Published Date: 23 October 2018

Long non-coding RNA ZEB1-AS1 promotes cell invasion and epithelial to mesenchymal transition through inducing ZEB1 expression in cervical cancer

Cheng RJ, Li N, Yang SY, Liu L, Han SY

OncoTargets and Therapy 2018, 11:7245-7253

Published Date: 18 October 2018

The elevated glutaminolysis of bladder cancer and T cells in a simulated tumor microenvironment contributes to the up-regulation of PD-L1 expression by interferon-γ

Wang LP, Yang XC, Li D, Liang ZJ, Chen YB, Ma GF, Wang YH, Li YX, Liang Y, Niu HT

OncoTargets and Therapy 2018, 11:7229-7243

Published Date: 18 October 2018

TNFα promotes glioblastoma A172 cell mitochondrial apoptosis via augmenting mitochondrial fission and repression of MAPK–ERK–YAP signaling pathways

Lu C, Chen X, Wang Q, Xu X, Xu B

OncoTargets and Therapy 2018, 11:7213-7227

Published Date: 18 October 2018

The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes

Devor EJ, Cha E, Warrier A, Miller MD, Gonzalez-Bosquet J, Leslie KK

OncoTargets and Therapy 2018, 11:7205-7211

Published Date: 18 October 2018

Knockdown of lncRNA UCA1 inhibits proliferation and invasion of papillary thyroid carcinoma through regulating miR-204/IGFBP5 axis

Liu H, Li R, Guan L, Jiang T

OncoTargets and Therapy 2018, 11:7197-7204

Published Date: 18 October 2018

Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma

Su L, Tian J, Sun J, Han N, Feng L, Yu B, Wang Y

OncoTargets and Therapy 2018, 11:7187-7196

Published Date: 18 October 2018

Dosimetric comparison of volumetric-modulated arc therapy and intensity-modulated radiation therapy in patients with cervical cancer: a meta-analysis

Bai W, Kou C, Yu W, Li Y, Hua W, Yu L, Wang J

OncoTargets and Therapy 2018, 11:7179-7186

Published Date: 18 October 2018

Prognostic value of NEK2 overexpression in digestive system cancers: a meta-analysis and systematic review

Ren Q, Li B, Liu M, Hu Z, Wang Y

OncoTargets and Therapy 2018, 11:7169-7178

Published Date: 18 October 2018

Gene expression analyses identify a relationship between stanniocalcin 2 and the malignant behavior of colorectal cancer

Wang J, Sahengbieke S, Xu X, Zhang L, Xu X, Sun L, Deng Q, Wang D, Chen D, Pan Y, Liu Z, Yu S

OncoTargets and Therapy 2018, 11:7155-7168

Published Date: 18 October 2018

Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration

Ciccarelli O, Colson A, De Saeger C, Reding R, Sempoux C, Leclercq IA, Stärkel P

OncoTargets and Therapy 2018, 11:7143-7153

Published Date: 17 October 2018

Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma

Zhang DY, Liu Z, Lu Z, Sun WL, Ma X, Zhang P, Wu BQ, Cui PY

OncoTargets and Therapy 2018, 11:7133-7142

Published Date: 17 October 2018

Overexpression of APC11 predicts worse survival in lung adenocarcinoma

Zhou J, Zhang S, Fu G, He Z, Xu Y, Ye W, Chen Z

OncoTargets and Therapy 2018, 11:7125-7132

Published Date: 17 October 2018

MicroRNA-195: a review of its role in cancers

Yu W, Liang X, Li X, Zhang Y, Sun Z, Liu Y, Wang J

OncoTargets and Therapy 2018, 11:7109-7123

Published Date: 17 October 2018

Review

Mechanisms of resistance to BRAF and MEK inhibitors and clinical update of US Food and Drug Administration-approved targeted therapy in advanced melanoma

Kakadia S, Yarlagadda N, Awad R, Kundranda M, Niu J, Naraev B, Mina L, Dragovich T, Gimbel M, Mahmoud F

OncoTargets and Therapy 2018, 11:7095-7107

Published Date: 17 October 2018

Novel EXO-T vaccine using polyclonal CD4+ T cells armed with HER2-specific exosomes for HER2-positive breast cancer

Li R, Chibbar R, Xiang J

OncoTargets and Therapy 2018, 11:7089-7093

Published Date: 17 October 2018

A systematic review and meta-analysis on the effect of angiogenesis blockade for the treatment of gastric cancer

Bai ZG, Zhang ZT

OncoTargets and Therapy 2018, 11:7077-7087

Published Date: 17 October 2018

Platelet-to-lymphocyte ratio and lymphocyte-to-white blood cell ratio predict the efficacy of neoadjuvant chemotherapy and the prognosis of locally advanced gastric cancer patients treated with the oxaliplatin and capecitabine regimen

Tang C, Cheng X, Yu S, Wang Y, Hou J, Li Q, Shen Z, Liu T, Cui Y

OncoTargets and Therapy 2018, 11:7061-7075

Published Date: 17 October 2018

The functional verification of EGFR-CAR T-cells targeted to hypopharyngeal squamous cell carcinoma

Dong Y, Ding Y, Guo W, Huang J, Yang Z, Zhang Y, Chen X

OncoTargets and Therapy 2018, 11:7053-7059

Published Date: 16 October 2018

Review

Clinical use of FLT3 inhibitors in acute myeloid leukemia

Sutamtewagul G, Vigil CE

OncoTargets and Therapy 2018, 11:7041-7052

Published Date: 16 October 2018

Original Research

Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells

Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T

OncoTargets and Therapy 2018, 11:7031-7040

Published Date: 16 October 2018

Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway

Khophai S, Thanee M, Techasen A, Namwat N, Klanrit P, Titapun A, Jarearnrat A, Sa-Ngiamwibool P, Loilome W

OncoTargets and Therapy 2018, 11:7019-7029

Published Date: 16 October 2018

Research progress of the clinicopathologic features of lung adenosquamous carcinoma

Wang J, Wang Y, Tong M, Pan H, Li D

OncoTargets and Therapy 2018, 11:7011-7017

Published Date: 16 October 2018

Review

TIM-3, a promising target for cancer immunotherapy

He Y, Cao J, Zhao C, Li X, Zhou C, Hirsch FR

OncoTargets and Therapy 2018, 11:7005-7009

Published Date: 16 October 2018

Decreased pretherapy serum apolipoprotein A-I is associated with extent of metastasis and poor prognosis of non-small-cell lung cancer

Shi H, Huang H, Pu J, Shi DC, Ning Y, Dong Y, Han Y, Zarogoulidis P, Bai C

OncoTargets and Therapy 2018, 11:6995-7003

Published Date: 15 October 2018

Inhibition of miR-10a-5p suppresses cholangiocarcinoma cell growth through downregulation of Akt pathway

Gao L, Yang X, Zhang H, Yu M, Long J, Yang T

OncoTargets and Therapy 2018, 11:6981-6994

Published Date: 15 October 2018

Genome-scale analysis identifies SERPINE1 and SPARC as diagnostic and prognostic biomarkers in gastric cancer

Liao P, Li W, Liu RZ, Teer JK, Xu BB, Zhang W, Li X, Mcleod HL, He YJ

OncoTargets and Therapy 2018, 11:6969-6980

Published Date: 15 October 2018

Original Research

Identification of critically carcinogenesis-related genes in basal cell carcinoma

Dai J, Lin K, Huang Y, Lu Y, Chen W, Zhang X, He B, Pan Y, Wang S, Fan W

OncoTargets and Therapy 2018, 11:6957-6967

Published Date: 15 October 2018

Original Research

Identification of driver genes associated with chemotherapy resistance of Ewing’s sarcoma

Liao H, Xie X, Xu Y, Huang G

OncoTargets and Therapy 2018, 11:6947-6956

Published Date: 15 October 2018

Crizotinib presented with promising efficacy but for concomitant mutation in next-generation sequencing-identified ROS1-rearranged non-small-cell lung cancer

Zeng L, Li Y, Xiao L, Xiong Y, Liu L, Jiang W, Heng J, Qu J, Yang N, Zhang Y

OncoTargets and Therapy 2018, 11:6937-6945

Published Date: 15 October 2018

Original Research

SMAGP a novel biomarker of cervical cancer development and progression

Jia Y, Li H, Liu G, Song F

OncoTargets and Therapy 2018, 11:6925-6935

Published Date: 15 October 2018

Original Research

NFATC2 is a novel therapeutic target for colorectal cancer stem cells

Lang T, Ding X, Kong L, Zhou X, Zhang Z, Ju HX, Ding S

OncoTargets and Therapy 2018, 11:6911-6924

Published Date: 15 October 2018

Targeting VEGF pathway to normalize the vasculature: an emerging insight in cancer therapy

Wu J, Tang Y, Liang X

OncoTargets and Therapy 2018, 11:6901-6909

Published Date: 17 October 2018

Synergistic suppression effect on tumor growth of acute myeloid leukemia by combining cytarabine with an engineered oncolytic vaccinia virus

Peng J, Wang S, Fan W, Li S, Wu Y, Mou X, Wang J, Tong X

OncoTargets and Therapy 2018, 11:6887-6900

Published Date: 15 October 2018

Original Research

Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma

Okuno K, Matsubara T, Nakamura T, Iino T, Kakimoto T, Asanuma K, Matsumine A, Sudo A

OncoTargets and Therapy 2018, 11:6879-6886

Published Date: 12 October 2018

Downregulation of miR-638 promotes progression of breast cancer and is associated with prognosis of breast cancer patients

Li M, Wang J, Liu H

OncoTargets and Therapy 2018, 11:6871-6877

Published Date: 12 October 2018

Low-dose hypomethylating agent decitabine in combination with aclacinomycin and cytarabine achieves a better outcome than standard FLAG chemotherapy in refractory/relapsed acute myeloid leukemia patients with poor-risk cytogenetics and mutations

Li L, Zhang X, Yu H, Zhang M, Xu M, Liu J, Fu Y, Meng H, Lyu C, Li X, Zhou J

OncoTargets and Therapy 2018, 11:6863-6870

Published Date: 12 October 2018

Case report

Malignant mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma harboring an EGFR mutation: a case report

Wang Y, Yang JX, Yu M, Cao DY, Shen K

OncoTargets and Therapy 2018, 11:6853-6862

Published Date: 12 October 2018

The lncRNA TUG1 promotes epithelial ovarian cancer cell proliferation and invasion via the WNT/β-catenin pathway

Liu S, Liu Y, Lu Q, Zhou X, Chen L, Liang W

OncoTargets and Therapy 2018, 11:6845-6851

Published Date: 12 October 2018

Case report

Renal Ewing sarcoma/primitive neuroectodermal tumor in a pregnant woman who underwent robot-assisted laparoscopic nephrectomy: a case report and literature review

Miao C, Yang J, Xue J, Zhu J, Chen W, Qin Y, Wang Z

OncoTargets and Therapy 2018, 11:6839-6843

Published Date: 11 October 2018

Original Research

Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells

O'Day EM, Idos GE, Hill C, Chen JW, Wagner G

OncoTargets and Therapy 2018, 11:6827-6838

Published Date: 11 October 2018

Original Research

SATB1 siRNA-encapsulated immunoliposomes conjugated with CD44 antibodies target and eliminate gastric cancer-initiating cells

Yang F, Zheng Z, Zheng L, Qin J, Li H, Xue X, Gao J, Fang G

OncoTargets and Therapy 2018, 11:6811-6825

Published Date: 11 October 2018

EGFR-TKI-based vs non-EGFR-TKI-based adjuvant therapy in resected non-small-cell lung cancer with EGFR mutations: a meta-analysis of randomized controlled trials

Wu JX, He Q, Ye F, Zhou QX, Chen HJ, Sun L, Wu H

OncoTargets and Therapy 2018, 11:6803-6810

Published Date: 11 October 2018

Upregulation of AKIP1 contributes to metastasis and progression and predicts poor prognosis of patients with colorectal cancer

Jiang W, Yang W, Yuan L, Liu F

OncoTargets and Therapy 2018, 11:6795-6801

Published Date: 11 October 2018

Metastatic malignancies and the effect on arterial stiffness and blood pressure levels: the possible role of chemotherapy

Res E, Kyvelou SM, Vlachopoulos C, Manousou K, Tousoulis D, Stefanadis C, Pektasides D

OncoTargets and Therapy 2018, 11:6785-6793

Published Date: 11 October 2018

MicroRNA-647 promotes the therapeutic effectiveness of argon–helium cryoablation and inhibits cell proliferation through targeting TRAF2 via the NF-κB signaling pathway in non-small cell lung cancer

Zhang YS, Chen T, Cai Y, Dong J, Bai F, Gao X, Tian L, Duan N, Liu D

OncoTargets and Therapy 2018, 11:6777-6784

Published Date: 10 October 2018

Clinical significance of serum total oxidant/antioxidant status in patients with operable and advanced gastric cancer

Du X, Zhang L, Zhang D, Yang L, Fan Y, Dong S

OncoTargets and Therapy 2018, 11:6767-6775

Published Date: 10 October 2018

Overexpression of long noncoding RNA NORAD in colorectal cancer associates with tumor progression

Wang L, Du L, Duan W, Yan S, Xie Y, Wang C

OncoTargets and Therapy 2018, 11:6757-6766

Published Date: 10 October 2018

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells

Pan B, Han H, Wu L, Xiong Y, Zhang J, Dong B, Yang Y, Chen J

OncoTargets and Therapy 2018, 11:6741-6756

Published Date: 10 October 2018

Role of monocyte-to-lymphocyte ratio in predicting sorafenib response in patients with advanced hepatocellular carcinoma

Zhu Z, Xu L, Zhuang L, Ning Z, Zhang C, Yan X, Lin J, Shen Y, Wang P, Meng Z

OncoTargets and Therapy 2018, 11:6731-6740

Published Date: 10 October 2018

Circ-DLG 1 promotes the proliferation of esophageal squamous cell carcinoma

Rong J, Wang Q, Zhang Y, Zhu D, Sun H, Tang W, Wang R, Shi W, Cao XF

OncoTargets and Therapy 2018, 11:6723-6730

Published Date: 9 October 2018

Original Research

Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo

Chen M, Lu J, Wei W, Lv Y, Zhang X, Yao Y, Wang L, Ling T, Zou X

OncoTargets and Therapy 2018, 11:6705-6722

Published Date: 10 October 2018

Knockdown of RAI14 suppresses the progression of gastric cancer

Chen C, Maimaiti A, Zhang X, Qu H, Sun Q, He Q, Yu W

OncoTargets and Therapy 2018, 11:6693-6703

Published Date: 9 October 2018

Effects of thyrotropin suppression on lumber bone mineral density in postmenopausal women with differentiated thyroid carcinoma

Zhang P, Xi H, Yan R

OncoTargets and Therapy 2018, 11:6687-6692

Published Date: 9 October 2018

Clinical significance and biological roles of cyclins in gastric cancer

Zhang HP, Li SY, Wang JP, Lin J

OncoTargets and Therapy 2018, 11:6673-6685

Published Date: 9 October 2018

Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells

Jiang L, Liang QL, Liang WM, Zhang HJ, Huang J, Yuan GL, Peng XX, Cheng SA, Huang ZG, Zhang XN

OncoTargets and Therapy 2018, 11:6665-6671

Published Date: 9 October 2018

Original Research

YAP regulates ALDH1A1 expression and stem cell property of bladder cancer cells

Zhao AY, Dai YJ, Lian JF, Huang Y, Lin JG, Dai YB, Xu TW

OncoTargets and Therapy 2018, 11:6657-6663

Published Date: 10 October 2018

Original Research

Pim1 promotes cell proliferation and regulates glycolysis via interaction with MYC in ovarian cancer

Wu Y, Deng Y, Zhu J, Duan Y, Weng W, Wu XH

OncoTargets and Therapy 2018, 11:6647-6656

Published Date: 9 October 2018

Original Research

Predictive role of skin rash in advanced pancreatic cancer patients treated with gemcitabine plus erlotinib: a systematic review and meta-analysis

Zeng M, Feng Q, Lu M, Zhou J, Yang Z, Tang J

OncoTargets and Therapy 2018, 11:6633-6646

Published Date: 8 October 2018

Case report

Male accessory breast cancer on the abdominal wall: a case report and literature review

Zhong GB, Ye XQ, Liu JL, Xiao SZ, Huang QH, Wei W

OncoTargets and Therapy 2018, 11:6625-6631

Published Date: 8 October 2018

Original Research

Efficacy and safety of iodine-125 brachytherapy combined with chemotherapy in the treatment of advanced NSCLC in the elderly

Wu C, Li B, Sun G, Peng C, Xiang D

OncoTargets and Therapy 2018, 11:6617-6624

Published Date: 8 October 2018

Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro

Liu WJ, Wang H, Peng XW, Wang WD, Liu NW, Wang Y, Lu Y

OncoTargets and Therapy 2018, 11:6605-6615

Published Date: 8 October 2018

Case report

Complete response associated with lenalidomide and celecoxib in a case of primary refractory Hodgkin lymphoma

Garcia-Recio M, Martinez-Serra J, Mestre F, Bento L, Gines J, Ramos R, Daumal J, López P, Sampol A, Gutierrez A

OncoTargets and Therapy 2018, 11:6599-6603

Published Date: 8 October 2018

Original Research

Nodal regulates bladder cancer cell migration and invasion via the ALK/Smad signaling pathway

Li Y, Zhong W, Zhu M, Hu S, Su X

OncoTargets and Therapy 2018, 11:6589-6597

Published Date: 5 October 2018

Knockdown of RNF6 inhibits gastric cancer cell growth by suppressing STAT3 signaling

Huang Z, Cai Y, Yang C, Chen Z, Sun H, Xu Y, Chen W, Xu D, Tian W, Wang H

OncoTargets and Therapy 2018, 11:6579-6587

Published Date: 5 October 2018

Original Research

Effects of insulin-like growth factor binding protein 3 on apoptosis of cutaneous squamous cell carcinoma cells

Liu J, Guo Y, Huang Y, Xue H, Bai S, Zhu J, Xia X, Shen B, Fang W

OncoTargets and Therapy 2018, 11:6569-6577

Published Date: 5 October 2018

Original Research

Radiofrequency Ablation of hepatocellular carcinoma: a meta-analysis of overall survival and recurrence-free survival

Casadei Gardini A, Marisi G, Canale M, Foschi FG, Donati G, Ercolani G, Valgiusti M, Passardi A, Frassineti GL, Scarpi E

OncoTargets and Therapy 2018, 11:6555-6567

Published Date: 5 October 2018

Original Research

The efficacy and safety of apatinib for refractory malignancies: a review and meta-analysis

Sun D, Hou H, Zhang C, Zhang X

OncoTargets and Therapy 2018, 11:6539-6554

Published Date: 5 October 2018

Review

Pembrolizumab for the treatment of patients with recurrent locally advanced or metastatic gastric or gastroesophageal junction cancer: an evidence-based review of place in therapy

Mehta R, Shah A, Almhanna K

OncoTargets and Therapy 2018, 11:6525-6537

Published Date: 4 October 2018

Review

Immune-checkpoint inhibitors for combating T-cell dysfunction in cancer

Grywalska E, Pasiarski M, Góźdź S, Roliński J

OncoTargets and Therapy 2018, 11:6505-6524

Published Date: 4 October 2018

Original Research

miR-431-5p alters the epithelial-to-mesenchymal transition markers by targeting UROC28 in hepatoma cells

Kong Q, Han J, Deng H, Wu F, Guo S, Ye Z

OncoTargets and Therapy 2018, 11:6489-6503

Published Date: 4 October 2018

The regulation of cytokine signaling by retinal determination gene network pathway in cancer

Zheng X, Liu Q, Yi M, Qin S, Wu K

OncoTargets and Therapy 2018, 11:6479-6487

Published Date: 4 October 2018

Review

Evolving role of neurokinin 1-receptor antagonists for chemotherapy-induced nausea and vomiting

Navari RM, Schwartzberg LS

OncoTargets and Therapy 2018, 11:6459-6478

Published Date: 4 October 2018

TRIM28 is overexpressed in glioma and associated with tumor progression

Su C, Li H, Gao W

OncoTargets and Therapy 2018, 11:6447-6458

Published Date: 10 October 2018

Original Research

Radix Tetrastigma hemsleyani flavone exhibits antitumor activity in colorectal cancer via Wnt/β-catenin signaling pathway

Wu X, Yu N, Zhang Y, Ye Y, Sun W, Ye L, Wu H, Yang Z, Wu L, Wang F

OncoTargets and Therapy 2018, 11:6437-6446

Published Date: 4 October 2018

Original Research

Co-expression network analysis identified CDH11 in association with progression and prognosis in gastric cancer

Chen PF, Wang F, Nie JY, Feng JR, Liu J, Zhou R, Wang HL, Zhao Q

OncoTargets and Therapy 2018, 11:6425-6436

Published Date: 2 October 2018

Review

LncRNA as a diagnostic and prognostic biomarker in bladder cancer: a systematic review and meta-analysis

Quan J, Pan X, Zhao L, Li Z, Dai K, Yan F, Liu S, Ma H, Lai Y

OncoTargets and Therapy 2018, 11:6415-6424

Published Date: 4 October 2018

Original Research

Adverse events risk associated with regorafenib in the treatment of advanced solid tumors: meta-analysis of randomized controlled trials

Yin X, Yin Y, Shen C, Chen H, Wang J, Cai Z, Chen Z, Zhang B

OncoTargets and Therapy 2018, 11:6405-6414

Published Date: 2 October 2018

Original Research

H19 induced by oxidative stress confers temozolomide resistance in human glioma cells via activating NF-κB signaling

Duan S, Li M, Wang Z, Wang L, Liu Y

OncoTargets and Therapy 2018, 11:6395-6404

Published Date: 2 October 2018

Original Research

LINC00460 modulates KDM2A to promote cell proliferation and migration by targeting miR-342-3p in gastric cancer

Wang F, Liang S, Liu X, Han L, Wang J, Du Q

OncoTargets and Therapy 2018, 11:6383-6394

Published Date: 2 October 2018

Case report

Elemene treatment for NSCLC with multiple CNS metastases: a case report and literature review

Han YS, Zhang X, Lu Y, Dong Y, Fu H, Zhang B, Gao Y

OncoTargets and Therapy 2018, 11:6377-6382

Published Date: 2 October 2018

Original Research

NOP7 interacts with β-catenin and activates β-catenin/TCF signaling in hepatocellular carcinoma cells

Wu N, Zhao J, Yuan Y, Lu C, Zhu W, Jiang Q

OncoTargets and Therapy 2018, 11:6369-6376

Published Date: 1 October 2018

Siva-1 emerges as a tissue-specific oncogene beyond its classic role of a proapoptotic gene

Vachtenheim J Jr, Lischke R, Vachtenheim J

OncoTargets and Therapy 2018, 11:6361-6367

Published Date: 1 October 2018

Original Research

Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B

Cao X, He GZ

OncoTargets and Therapy 2018, 11:6351-6360

Published Date: 1 October 2018

Original Research

MicroRNA-1225-5p behaves as a tumor suppressor in human glioblastoma via targeting of IRS1

Li D, Chi G, Chen Z, Jin X

OncoTargets and Therapy 2018, 11:6339-6350

Published Date: 28 September 2018

Original Research

Efficacy and safety of weekly nab-paclitaxel plus cisplatin with concurrent intensity-modulated radiotherapy in patients with inoperable, locally advanced esophageal cancer: a pilot trial

Wang D, Zhang W, Qian D, Guan Y, Chen X, Zhang H, Wang J, Pang Q

OncoTargets and Therapy 2018, 11:6333-6338

Published Date: 28 September 2018

Case report

Extramedullary relapse of acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation treated by CAR T-cell therapy: a case report

Wang D, Shi R, Wang Q, Li J

OncoTargets and Therapy 2018, 11:6327-6332

Published Date: 28 September 2018

A ten-long non-coding RNA signature for predicting prognosis of patients with cervical cancer

Shen L, Yu H, Liu M, Wei D, Liu W, Li C, Chang Q

OncoTargets and Therapy 2018, 11:6317-6326

Published Date: 28 September 2018

miR-218 overexpression suppresses tumorigenesis of papillary thyroid cancer via inactivation of PTEN /PI3K/AKT pathway by targeting Runx2

Han M, Chen L, Wang Y

OncoTargets and Therapy 2018, 11:6305-6316

Published Date: 28 September 2018

LINC00152 promotes the growth and invasion of oral squamous cell carcinoma by regulating miR-139-5p

Li M, Ning J, Li Z, Wang J, Zhao C, Wang L

OncoTargets and Therapy 2018, 11:6295-6304

Published Date: 27 September 2018

Original Research

Predictive value of LDH kinetics in bevacizumab treatment and survival of patients with advanced NSCLC

Li B, Li C, Guo M, Shang S, Li X, Xie P, Sun X, Yu J, Wang L

OncoTargets and Therapy 2018, 11:6287-6294

Published Date: 27 September 2018

Original Research

Metabolic syndrome and the incidence of hepatocellular carcinoma: a meta-analysis of cohort studies

Chen Y, Li X, Wu S, Ye W, Lou L

OncoTargets and Therapy 2018, 11:6277-6285

Published Date: 27 September 2018

Case report

POEMS syndrome complicated with multiple ischemic vascular events: case report and review of literature

Găman M, Vlădăreanu AM, Dobrea C, Onisâi M, Marinescu C, Cîşleanu D, Ciufu C, Vasile D, Bumbea H, Voican I

OncoTargets and Therapy 2018, 11:6271-6276

Published Date: 27 September 2018

Effect of long non-coding RNA AOC4P on gastrointestinal stromal tumor cells

Hu JC, Wang Q, Jiang LX, Cai L, Zhai HY, Yao ZW, Zhang ML, Feng Y

OncoTargets and Therapy 2018, 11:6259-6269

Published Date: 26 September 2018

Overexpression of GPR35 confers drug resistance in NSCLC cells by β-arrestin/Akt signaling

Wang W, Han T, Tong W, Zhao J, Qiu X

OncoTargets and Therapy 2018, 11:6249-6257

Published Date: 26 September 2018

Original Research

PLK1 as a potential prognostic marker of gastric cancer through MEK-ERK pathway on PDTX models

Dang SC, Fan YY, Cui L, Chen JX, Qu JG, Gu M

OncoTargets and Therapy 2018, 11:6239-6247

Published Date: 25 September 2018

Review

Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities

Chaar M, Kamta J, Ait-Oudhia S

OncoTargets and Therapy 2018, 11:6227-6237

Published Date: 25 September 2018

MicroRNA-671-3p promotes the proliferation and migration of glioma cells via targeting CKAP4

Lu GF, You CY, Chen YS, Jiang H, Zheng X, Tang W, Wang X, Xu H, Geng F

OncoTargets and Therapy 2018, 11:6217-6226

Published Date: 25 September 2018

CAV2 promotes the growth of renal cell carcinoma through the EGFR/PI3K/Akt pathway

Liu F, Shangli Z, Hu Z

OncoTargets and Therapy 2018, 11:6209-6216

Published Date: 25 September 2018

SOX2, a stemness gene, induces progression of NSCLC A549 cells toward anchorage-independent growth and chemoresistance to vinblastine

Choe C, Kim H, Min S, Park S, Seo J, Roh S

OncoTargets and Therapy 2018, 11:6197-6207

Published Date: 25 September 2018

Review

Immunotherapy combined with epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer treatment

Liang H, Liu X, Wang M

OncoTargets and Therapy 2018, 11:6189-6196

Published Date: 25 September 2018

Original Research

All-trans retinoic acid-encapsulated, CD20 antibody-conjugated poly(lactic-co-glycolic acid) nanoparticles effectively target and eliminate melanoma-initiating cells in vitro

Chen X, Zhang Z, Yang S, Chen H, Wang D, Li J

OncoTargets and Therapy 2018, 11:6177-6187

Published Date: 25 September 2018

Clinical, dosimetric, and position factors for radiation-induced acute esophagitis in intensity-modulated (chemo)radiotherapy for locally advanced non-small-cell lung cancer

Huang J, He TY, Yang RH, Ji TL, Li G

OncoTargets and Therapy 2018, 11:6167-6175

Published Date: 21 September 2018

CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial–mesenchymal transition

Cao G, Chen D, Liu G, Pan Y, Liu Q

OncoTargets and Therapy 2018, 11:6153-6165

Published Date: 21 September 2018

Case report

Scalp metastases as first presentation of pulmonary adenocarcinomas: a case report

Yu Q, Subedi S, Tong Y, Wei Q, Xu H, Wang Y, Gong Y, Shi Y

OncoTargets and Therapy 2018, 11:6147-6151

Published Date: 21 September 2018

Original Research

Distribution of CD4+ and CD8+ exhausted tumor-infiltrating lymphocytes in molecular subtypes of Chinese breast cancer patients

Shi F, Chang H, Zhou Q, Zhao YJ, Wu GJ, Song QK

OncoTargets and Therapy 2018, 11:6139-6145

Published Date: 21 September 2018

Original Research

Is long interval from neoadjuvant chemoradiotherapy to surgery optimal for rectal cancer in the era of intensity-modulated radiotherapy?: a prospective observational study

Chang H, Jiang W, Ye WJ, Tao YL, Wang QX, Xiao WW, Gao YH

OncoTargets and Therapy 2018, 11:6129-6138

Published Date: 21 September 2018

Review

Efficacy and safety of apatinib treatment for gastric cancer, hepatocellular carcinoma and non-small cell lung cancer: a meta-analysis

Xue J, Astère M, Zhong M, Lin H, Shen J, Zhu Y

OncoTargets and Therapy 2018, 11:6119-6128

Published Date: 21 September 2018

Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy

Li L, Zhang S, Xie D, Chen H, Zheng X, Pan D

OncoTargets and Therapy 2018, 11:6111-6118

Published Date: 20 September 2018

Lentivirus-mediated shRNA targeting MUTYH inhibits malignant phenotypes of bladder cancer SW780 cells

Gao Q, Liu Y, Xie H, Zhong Y, Liao X, Zhan H, Zhou Q, Ding M, Yang K, Li A, Liu Y, Mei HB, Cai Z

OncoTargets and Therapy 2018, 11:6101-6109

Published Date: 21 September 2018

Efficacy and safety of trastuzumab as maintenance or palliative therapy in advanced HER2-positive gastric cancer

Fu XM, Zhang Y, Yang J, Qi YL, Ming Y, Sun MM, Shang YM, Yang YH, Zhu XY, Gao QL

OncoTargets and Therapy 2018, 11:6091-6100

Published Date: 20 September 2018

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6

Chen C, Zhang Z, Li J, Sun Y

OncoTargets and Therapy 2018, 11:6081-6090

Published Date: 20 September 2018

LINK-A promotes cell proliferation through the regulation of aerobic glycolysis in non-small-cell lung cancer

Zhao W, Li W, Dai W, Huang N, Qiu J

OncoTargets and Therapy 2018, 11:6071-6080

Published Date: 20 September 2018

Review

Comparison of short-term outcomes between minimally invasive McKeown and Ivor Lewis esophagectomy for esophageal or junctional cancer: a systematic review and meta-analysis

Deng J, Su Q, Ren Z, Wen J, Xue Z, Zhang L, Chu X

OncoTargets and Therapy 2018, 11:6057-6069

Published Date: 20 September 2018

Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature

Gallo S, Arcidiacono MV, Tisato V, Piva R, Penolazzi L, Bosi C, Feo CV, Gafà R, Secchiero P

OncoTargets and Therapy 2018, 11:6049-6056

Published Date: 20 September 2018

Original Research

Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo

Wang Y, Meng Y, Zhang S, Wu H, Yang D, Nie C, Hu Q

OncoTargets and Therapy 2018, 11:6039-6048

Published Date: 20 September 2018

Original Research

Oldhamianoside inhibits the growth of ovarian cancer both in vitro and in vivo via adjusting inflammation and angiogenesis signals

Li Z, Zuo Y, Hou L, Dong L, Sun X

OncoTargets and Therapy 2018, 11:6031-6037

Published Date: 19 September 2018

The predictive ability of plasma ESR 1 mutations for the efficacy of endocrine therapy in hormone-receptor-positive advanced breast cancer

Du YF, Li N, Jiao X, Li K, Yan SC

OncoTargets and Therapy 2018, 11:6023-6029

Published Date: 19 September 2018

Original Research

Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesis

Zhang X, Feng H, Li Z, Li D, Liu S, Huang H, Li M

OncoTargets and Therapy 2018, 11:6001-6021

Published Date: 19 September 2018

Prognostic value of miR-17-5 p in gastrointestinal cancers: a systematic review and meta-analysis

Wang Z, Zhang J, Zhang Z, Jiang Y, Li M, Li Q, Bai L, Yao D, Wang M, Wang X

OncoTargets and Therapy 2018, 11:5991-5999

Published Date: 19 September 2018

Review

PD1/PDL1 inhibitors for the treatment of advanced urothelial bladder cancer

Stenehjem DD, Tran D, Nkrumah MA, Gupta S

OncoTargets and Therapy 2018, 11:5973-5989

Published Date: 19 September 2018

TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression

Gao C, Qiao T, Zhang B, Yuan S, Zhuang X, Luo Y

OncoTargets and Therapy 2018, 11:5963-5971

Published Date: 18 September 2018

Case report

Treatment with olaparib monotherapy for BRCA2-mutated refractory intrahepatic cholangiocarcinoma: a case report

Cheng Y, Zhang J, Qin SK, Hua HQ

OncoTargets and Therapy 2018, 11:5957-5962

Published Date: 18 September 2018

Original Research

Identification of the predictive genes for the response of colorectal cancer patients to FOLFOX therapy

Lin HJ, Qiu XK, Zhang B, Zhang JC

OncoTargets and Therapy 2018, 11:5943-5955

Published Date: 17 September 2018

Osteopontin promotes cancer cell drug resistance, invasion, and lactate production and is associated with poor outcome of patients with advanced non-small-cell lung cancer

Ouyang XP, Huang Y, Jin X, Zhao W, Hu T, Wu F, Huang J

OncoTargets and Therapy 2018, 11:5933-5941

Published Date: 19 September 2018

Case report

Successful treatment of recurrent rectal implantation metastasis of ovarian cancer by natural orifice specimen extraction surgery: a case report

Su H, Li B, Ren W, Bao M, Wang P, Liu Q, Wang X, Zhou Z, Zhou H

OncoTargets and Therapy 2018, 11:5925-5931

Published Date: 17 September 2018

Original Research

Lipoprotein (a): a promising prognostic biomarker in patients with hepatocellular carcinoma after curative resection

Gao XH, Zhang SS, Chen H, Wang K, Xie W, Wang F

OncoTargets and Therapy 2018, 11:5917-5924

Published Date: 17 September 2018

Review

Therapy-related myeloid neoplasms: clinical perspectives

Fianchi L, Criscuolo M, Fabiani E, Falconi G, Maraglino AME, Voso MT, Pagano L

OncoTargets and Therapy 2018, 11:5909-5915

Published Date: 17 September 2018

Original Research

Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study

Guo J, Yang L, Cai J, Xu L, Min J, Shen Y, Xiong Z, Dong W, Bunyamanop V, Wang Z

OncoTargets and Therapy 2018, 11:5903-5908

Published Date: 18 September 2018

Elevated urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine and serum uric acid are associated with progression and are prognostic factors of colorectal cancer

Mao L, Guo C, Zheng S

OncoTargets and Therapy 2018, 11:5895-5902

Published Date: 17 September 2018

MicroRNA-140-3p enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by targeting pregnenolone X receptor

Li J, Zhao J, Wang H, Li X, Liu A, Qin Q, Li B

OncoTargets and Therapy 2018, 11:5885-5894

Published Date: 17 September 2018

A case of interstitial lung disease with alveolar hemorrhage induced by pembrolizumab

Sugano T, Seike M, Noro R, Kaburaki S, Tozuka T, Takahashi A, Takano N, Tanaka T, Kashiwada T, Takeuchi S, Minegishi Y, Saito Y, Kubota K, Terasaki Y, Gemma A

OncoTargets and Therapy 2018, 11:5879-5883

Published Date: 17 September 2018

Estrogen affects cell growth and IGF-1 receptor expression in renal cell carcinoma

Sun L, Gao Z, Luo L, Tan H, Zhang G

OncoTargets and Therapy 2018, 11:5873-5878

Published Date: 17 September 2018

Original Research

Evaluation of supportive and barrier-protective skin care products in the daily prevention and treatment of cutaneous toxicity during systemic chemotherapy

Lüftner D, Dell’Acqua V, Selle F, Khalil A, Leonardi MC, De La Torre Tomás A, Shenouda G, Romero Fernandez J, Orecchia R, Moyal D, Seité S

OncoTargets and Therapy 2018, 11:5865-5872

Published Date: 17 September 2018

DACH 1 inhibits glioma invasion and tumor growth via the Wnt/catenin pathway

Wang J, Zou Y, Wu X, Chen M, Zhang S, Lu X, Wang Q

OncoTargets and Therapy 2018, 11:5853-5863

Published Date: 17 September 2018

Original Research

Long-term response to first-line bevacizumab-based therapy in patients with metastatic breast cancer: results of the observational “LORENA” study

Redondo A, Ramos Vázquez M, Manso L, Gil Gil MJ, Garau Llinas I, García-Garre E, Rodríguez CA, Chacón JI, López-Vivanco G

OncoTargets and Therapy 2018, 11:5845-5852

Published Date: 17 September 2018

TMEM119 promotes gastric cancer cell migration and invasion through STAT3 signaling pathway

Zheng P, Wang W, Ji M, Zhu Q, Feng Y, Zhou F, He Q

OncoTargets and Therapy 2018, 11:5835-5844

Published Date: 13 September 2018

Combination of carcinoembryonic antigen with the American Joint Committee on Cancer TNM staging system in rectal cancer: a real-world and large population-based study

Liu Q, Lian P, Luo D, Cai S, Li Q, Li X

OncoTargets and Therapy 2018, 11:5827-5834

Published Date: 13 September 2018

Apatinib combined with docetaxel as a salvage treatment for metastatic esophageal squamous cancer: a case report

Liang LJ, Wen YX, Xia YY, Wang L, Fei JY, Jiang XD

OncoTargets and Therapy 2018, 11:5821-5826

Published Date: 13 September 2018

Subgroup analysis reveals molecular heterogeneity and provides potential precise treatment for pancreatic cancers

Zhang H, Zeng J, Tan Y, Lu L, Sun C, Liang Y, Zou H, Yang X, Tan Y

OncoTargets and Therapy 2018, 11:5811-5819

Published Date: 12 September 2018

PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation

Lv JM, Chen L, Gao Y, Huang H, Pan XW, Liu X, Chen M, Qu FJ, Li L, Wang JK, Cui XG, Xu DF

OncoTargets and Therapy 2018, 11:5797-5809

Published Date: 12 September 2018

Association of GSTP1 and P16 promoter methylation with the risk of HBV-related hepatocellular carcinoma: a meta-analysis

Li Q, Deng CL, Zhang T, Li X

OncoTargets and Therapy 2018, 11:5789-5796

Published Date: 12 September 2018

Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips

Tong Q, Wang XL, Li SB, Yang GL, Jin S, Gao ZY, Liu XB

OncoTargets and Therapy 2018, 11:5777-5787

Published Date: 12 September 2018

Ultrasound-mediated microbubble destruction: a new method in cancer immunotherapy

Tu J, Zhang H, Yu J, Liufu C, Chen Z

OncoTargets and Therapy 2018, 11:5763-5775

Published Date: 12 September 2018

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

Gomari H, Forouzandeh Moghadam M, Soleimani M

OncoTargets and Therapy 2018, 11:5753-5762

Published Date: 12 September 2018

Long noncoding RNA SNHG6 promotes the progression of colorectal cancer through sponging miR-760 and activation of FOXC1

Zhu Y, Xing Y, Chi F, Sun W, Zhang Z, Piao D

OncoTargets and Therapy 2018, 11:5743-5752

Published Date: 12 September 2018

SOX5 induces lung adenocarcinoma angiogenesis by inducing the expression of VEGF through STAT3 signaling

Chen X, Zheng Q, Li W, Lu Y, Ni Y, Ma L, Fu Y

OncoTargets and Therapy 2018, 11:5733-5741

Published Date: 11 September 2018

IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446

Jin F, Miao Y, Xu P, Qiu X

OncoTargets and Therapy 2018, 11:5723-5731

Published Date: 11 September 2018

The incidence and risk factors of hepatotoxicity induced by perioperative hyperthermic intraperitoneal chemotherapy in gastrointestinal carcinoma patients: a retrospective study

Zheng Z, Yu H, Xiong B, Shen S, Yang H, Zhou YF

OncoTargets and Therapy 2018, 11:5715-5722

Published Date: 11 September 2018

Helicobacter pylori promotes gastric epithelial cell survival through the PLK1/PI3K/Akt pathway

Xu W, Huang Y, Yang Z, Hu Y, Shu X, Xie C, He C, Zhu Y, Lu N

OncoTargets and Therapy 2018, 11:5703-5713

Published Date: 11 September 2018

NEAT1_2—SFPQ axis mediates cisplatin resistance in liver cancer cells in vitro

Ru Y, Chen XJ, Guo WZ, Gao SG, Qi YJ, Chen P, Feng XS, Zhang SJ

OncoTargets and Therapy 2018, 11:5695-5702

Published Date: 11 September 2018

Volatile anesthetic sevoflurane suppresses lung cancer cells and miRNA interference in lung cancer cells

Wang L, Wang T, Gu JQ, Su HB

OncoTargets and Therapy 2018, 11:5689-5693

Published Date: 11 September 2018

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer

Ying Zhi L, Xu Z, Ning L, Jia Jin L, Hai Cui Y, Hong HG, Fang XJ

OncoTargets and Therapy 2018, 11:5677-5688

Published Date: 10 September 2018

The role of gene sculptor microRNAs in human precancerous lesions

Wang RH, He LY, Zhou SH

OncoTargets and Therapy 2018, 11:5667-5675

Published Date: 10 September 2018

MicroRNA-300 suppresses metastasis of oral squamous cell carcinoma by inhibiting epithelial-to-mesenchymal transition

Kang Y, Zhang Y, Sun Y, Wen Y, Sun F

OncoTargets and Therapy 2018, 11:5657-5666

Published Date: 10 September 2018

Upregulation of long noncoding RNA CCAT1-L promotes epithelial–mesenchymal transition in gastric adenocarcinoma

Fang H, Liu HM, Wu WH, Liu H, Pan Y, Li WJ

OncoTargets and Therapy 2018, 11:5647-5655

Published Date: 10 September 2018

The downregulated long noncoding RNA DHRS4-AS1 is protumoral and associated with the prognosis of clear cell renal cell carcinoma

Wang C, Wang G, Zhang Z, Wang Z, Ren M, Wang X, Li H, Yu Y, Liu J, Cai L, Li Y, Zhang D, Zhang C

OncoTargets and Therapy 2018, 11:5631-5646

Published Date: 10 September 2018

Low-frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in PTX-resistant PC-3 cells via the endoplasmic reticulum stress-mediated PI3K/Akt/mTOR signaling pathway

Wu Y, Liu X, Qin Z, Hu L, Wang X

OncoTargets and Therapy 2018, 11:5621-5630

Published Date: 10 September 2018

Podoplanin-positive cancer-associated fibroblasts predict poor prognosis in lung cancer patients

Hu G, Zhong K, Chen W, Wang S, Huang L

OncoTargets and Therapy 2018, 11:5607-5619

Published Date: 10 September 2018

Pembrolizumab and salvage chemotherapy in EGFR T790M-positive non-small-cell lung cancer with high PD-L1 expression

Tozuka T, Seike M, Minegishi Y, Kitagawa S, Kato T, Takano N, Hisakane K, Takahashi S, Kobayashi K, Kashiwada T, Sugano T, Takeuchi S, Kunugi S, Noro R, Saito Y, Kubota K, Gemma A

OncoTargets and Therapy 2018, 11:5601-5605

Published Date: 7 September 2018

Original Research

Preoperative high-sensitivity C-reactive protein to lymphocyte ratio index plays a vital role in the prognosis of hepatocellular carcinoma after surgical resection

Liao M, Chen P, Liao Y, Li J, Yao W, Sun T, Liao W, Su L

OncoTargets and Therapy 2018, 11:5591-5600

Published Date: 7 September 2018

RRM1 expression and the clinicopathological characteristics of patients with non-small cell lung cancer treated with gemcitabine

Chen Y, Huang Y, Chen DM, Wu C, Leng QP, Wang WY, Deng MQ, Zhao YX, Yang XH

OncoTargets and Therapy 2018, 11:5579-5589

Published Date: 7 September 2018

Hsa_circ_0003998 promotes cell proliferation and invasion by targeting miR-326 in non-small cell lung cancer

Yu W, Jiang H, Zhang H, Li J

OncoTargets and Therapy 2018, 11:5569-5577

Published Date: 7 September 2018

CXCR2 is a novel cancer stem-like cell marker for triple-negative breast cancer

Wang Y, Tu L, Du C, Xie X, Liu Y, Wang J, Li Z, Jiang M, Cao D, Yan X, Luo F

OncoTargets and Therapy 2018, 11:5559-5567

Published Date: 6 September 2018

Negative correlation of cytoplasm TIMP3 with miR-222 indicates a good prognosis for NSCLC

Lei Y, Liu Z, Yang W

OncoTargets and Therapy 2018, 11:5551-5557

Published Date: 6 September 2018

Case report

Effective treatment of pulmonary adenocarcinoma harboring triple EGFR mutations of L858R, T790M, and cis-C797S by osimertinib, bevacizumab, and brigatinib combination therapy: a case report

Zhao J, Zou M, Lv J, Han Y, Wang G, Wang G

OncoTargets and Therapy 2018, 11:5545-5550

Published Date: 6 September 2018

Nomograms for predicting long-term overall survival and disease-specific survival of patients with clear cell renal cell carcinoma

Zhang GH, Wu Y, Zhang JS, Fang ZQ, Liu ZX, Xu ZH, Fan YD

OncoTargets and Therapy 2018, 11:5535-5544

Published Date: 6 September 2018

Feasibility of radical hysterectomy in women with FIGO stage IIB cervical cancer: an observation study of 10-year experience in a tertiary center

Yuan L, Guo JQ, Zhang XC, Chen M, Xu CJ, Yao LQ

OncoTargets and Therapy 2018, 11:5527-5533

Published Date: 19 September 2018

Prognostic significance of NANOG expression in solid tumors: a meta-analysis

Zhao LQ, Liu J, Chen S, Fang C, Zhang XQ, Luo ZB

OncoTargets and Therapy 2018, 11:5515-5526

Published Date: 6 September 2018

An evaluation of the clinical diagnostic value of contrast-enhanced ultrasound combined with contrast-enhanced computed tomography in space-occupying lesions of the kidney [Corrigendum]

Lu J, Jiao D, Cong Z, Tian W

OncoTargets and Therapy 2018, 11:5513-5514

Published Date: 5 September 2018

Comparison of efficacy and toxicity between nedaplatin and cisplatin in treating malignant pleural effusion

Zhong LZ, Xu HY, Zhao ZM, Zhang GM, Lin FW

OncoTargets and Therapy 2018, 11:5509-5512

Published Date: 5 September 2018

Suppression of c-MET overcomes erlotinib resistance in tongue cancer cells

Huang K, Liu D

OncoTargets and Therapy 2018, 11:5499-5508

Published Date: 5 September 2018

Absence of AIF1L contributes to cell migration and a poor prognosis of breast cancer

Liu P, Li W, Hu Y, Jiang Y

OncoTargets and Therapy 2018, 11:5485-5498

Published Date: 5 September 2018

Altered fractionation radiotherapy with or without chemotherapy in the treatment of head and neck cancer: a network meta-analysis

Liu Y, Kou C, Bai W, Liu X, Song Y, Zhang L, Wang M, Zhang Y, You Y, Yin Y, Jiang X, Xin Y

OncoTargets and Therapy 2018, 11:5465-5483

Published Date: 4 September 2018

Clinical benefit of fulvestrant monotherapy in the multimodal treatment of hormone receptor and HER2 positive advanced breast cancer: a case series

Rusz O, Kószó R, Dobi Á, Csenki M, Valicsek E, Nikolényi A, Uhercsák G, Cserháti A, Kahán Z

OncoTargets and Therapy 2018, 11:5459-5463

Published Date: 4 September 2018

Prognostic value of CD44v6 expression in breast cancer: a meta-analysis

Qiao GL, Song LN, Deng ZF, Chen Y, Ma LJ

OncoTargets and Therapy 2018, 11:5451-5457

Published Date: 4 September 2018

Mifepristone inhibits proliferation, migration and invasion of HUUA cells and promotes its apoptosis by regulation of FAK and PI3K/AKT signaling pathway

Sang L, Lu D, Zhang J, Du S, Zhao X

OncoTargets and Therapy 2018, 11:5441-5449

Published Date: 4 September 2018

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage

Liu WJ, Yin YB, Sun JY, Feng S, Ma JK, Fu XY, Hou YJ, Yang MF, Sun BL, Fan CD

OncoTargets and Therapy 2018, 11:5429-5439

Published Date: 4 September 2018

MicroRNA 628 suppresses migration and invasion of breast cancer stem cells through targeting SOS1

Lin C, Gao B, Yan X, Lei Z, Chen K, Li Y, Zeng Q, Chen Z, Li H

OncoTargets and Therapy 2018, 11:5419-5428

Published Date: 4 September 2018

Postoperative adjuvant chemo (embolization) therapy for hepatocellular carcinoma with portal vein tumor thrombosis

Zhang YF, Shang H, Zeng XL, Ji H, Li YM, Lu HW

OncoTargets and Therapy 2018, 11:5407-5417

Published Date: 3 September 2018

RGD-modified nanoliposomes containing quercetin for lung cancer targeted treatment

Zhou X, Liu H, Zhao H, Wang T

OncoTargets and Therapy 2018, 11:5397-5405

Published Date: 3 September 2018

Successful cisplatin-etoposide chemotherapy-based treatment of a primary small cell neuroendocrine carcinoma of the tonsil with multiple metastases: a case report

Wang X, Chen Q, Meng J

OncoTargets and Therapy 2018, 11:5391-5395

Published Date: 3 September 2018

Expression profiles of long noncoding RNAs in lung adenocarcinoma

Zhao B, Xu H, Ai X, Adalat Y, Tong Y, Zhang J, Yang S

OncoTargets and Therapy 2018, 11:5383-5390

Published Date: 6 September 2018

STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells

Gao F, Yu XL, Meng RQ, Wang JS, Jia L

OncoTargets and Therapy 2018, 11:5371-5381

Published Date: 31 August 2018

SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer

Yi N, Xiao M, Jiang F, Liu Z, Ni W, Lu C, Ni R, Chen W

OncoTargets and Therapy 2018, 11:5359-5370

Published Date: 3 September 2018

Genome-wide profiling reveals cancer-related genes with switched alternative polyadenylation sites in colorectal cancer

Yang X, Wu J, Xu W, Tan S, Chen C, Wang X, Sun J, Kang Y

OncoTargets and Therapy 2018, 11:5349-5357

Published Date: 31 August 2018

Lymphangioleiomyomatosis: a case report and review of diagnosis and treatment

Liu Y, Guo Z, Zhao C, Li X, Liu H, Chen J

OncoTargets and Therapy 2018, 11:5339-5347

Published Date: 31 August 2018

Case Series

Apatinib mesylate tablet in the treatment of advanced malignant melanoma

Yang L, Zhu H, Luo P, Chen S, Xu Y, Wang C

OncoTargets and Therapy 2018, 11:5333-5338

Published Date: 31 August 2018

Prognostic role of long non-coding RNA HNF1A-AS1 in Chinese cancer patients: a meta-analysis

Zhuang C, Zheng L, Wang P

OncoTargets and Therapy 2018, 11:5325-5332

Published Date: 31 August 2018

Eukaryotic translation initiation factor 3 subunit G (EI F3G) resensitized HC T116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1

Yang C, Liu X, Li C, Li S, Du W, Yang D

OncoTargets and Therapy 2018, 11:5315-5324

Published Date: 31 August 2018

Original Research

E2F3 promotes cancer growth and is overexpressed through copy number variation in human melanoma

Feng Z, Peng C, Li D, Zhang D, Li X, Cui F, Chen Y, He Q

OncoTargets and Therapy 2018, 11:5303-5313

Published Date: 30 August 2018

miR-376a inhibits breast cancer cell progression by targeting neuropilin-1 NR

Zhang L, Chen Y, Wang H, Zheng X, Li C, Han Z

OncoTargets and Therapy 2018, 11:5293-5302