Adamczyk A, Kruczak A, Harazin-Lechowska A, Ambicka A, Grela-Wojewoda A, Domagała-Haduch M, Janecka-Widła A, Majchrzyk K, Cichocka A, Ryś J, Niemiec J

OncoTargets and Therapy 2018, 11:4525-4535

Published Date: 3 August 2018

Original Research

Melittin induces NSCLC apoptosis via inhibition of miR-183

Gao D, Zhang J, Bai L, Li F, Dong Y, Li Q

OncoTargets and Therapy 2018, 11:4511-4523

Published Date: 1 August 2018

Original Research

HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma

Wu CZ, Zheng JJ, Bai YH, Xia P, Zhang HC, Guo Y

OncoTargets and Therapy 2018, 11:4501-4510

Published Date: 1 August 2018

Original Research

Cancer/testis antigens (CTAs) expression in resected lung cancer

Jin S, Cao S, Li J, Meng Q, Wang C, Yao L, Lang Y, Cao J, Shen J, Pan B, Hu J, Yu Y

OncoTargets and Therapy 2018, 11:4491-4499

Published Date: 1 August 2018

Original Research

Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo

Zhang Y, Zhang XX, Yuan RY, Ren T, Shao ZY, Wang HF, Cai WL, Chen LT, Wang XA, Wang P

OncoTargets and Therapy 2018, 11:4479-4490

Published Date: 1 August 2018

Original Research

miR-141-3p is a key negative regulator of the EGFR pathway in osteosarcoma

Wang J, Wang G, Li B, Qiu C, He M

OncoTargets and Therapy 2018, 11:4461-4478

Published Date: 31 July 2018

Original Research

Metformin induces miR-378 to downregulate the CDK1, leading to suppression of cell proliferation in hepatocellular carcinoma

Zhou J, Han S, Qian W, Gu Y, Li X, Yang K

OncoTargets and Therapy 2018, 11:4451-4459

Published Date: 31 July 2018

Corrigendum

Effect of first-line endocrine therapy in patients with hormone-sensitive advanced breast cancer: a network meta-analysis [Corrigendum]

Zhang T, Feng F, Zhao W, Tian J, Yao Y, Zhou C, Dong S, Wang C, Zang C, Lv Q, Sun C

OncoTargets and Therapy 2018, 11:4449-4450

Published Date: 31 July 2018

Original Research

Outcome of eribulin as a late treatment line for Thai metastatic breast cancer patients

Ditsatham C, Chitapanarux I, Somwangprasert A, Watcharachan K, Wongmaneerung P, Charoentum C, Chewaskulyong B, Chakrabandhu S, Onchan W, Teeyasuntranonn A, Sripan P

OncoTargets and Therapy 2018, 11:4443-4447

Published Date: 31 July 2018

Original Research

LINC00888 promoted tumorigenicity of melanoma via miR-126/CRK signaling axis

Lu W, Tao X, Fan Y, Tang Y, Xu X, Fan S, Huang Y, Yu Y, Luo D

OncoTargets and Therapy 2018, 11:4431-4442

Published Date: 31 July 2018

Original Research

Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NFκB signaling pathway

Xue Y, Yang L, Li J, Yan Y, Jiang Q, Shen L, Yang S, Shen B, Huang R, Yan J, Guo H

OncoTargets and Therapy 2018, 11:4413-4429

Published Date: 30 July 2018

Case report

Reversible posterior leukoencephalopathy syndrome induced by apatinib: a case report and literature review

Li XT, Chai J, Wang Z, Lu L, Zhao QY, Zhou J, Ju F

OncoTargets and Therapy 2018, 11:4407-4411

Published Date: 30 July 2018

Original Research

Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest

Li XQ, Bai YL, Zhang DL, Jiao HS, He RX

OncoTargets and Therapy 2018, 11:4395-4405

Published Date: 27 July 2018

Review

HOXA11-AS: a novel regulator in human cancer proliferation and metastasis

Xue JY, Huang C, Wang W, Li HB, Sun Ming, Xie M

OncoTargets and Therapy 2018, 11:4387-4393

Published Date: 27 July 2018

Original Research

Extracts and components of Ficus carica leaves suppress survival, cell cycle, and migration of triple-negative breast cancer MDA-MB-231 cells

Zhang Y, Wan Y, Huo B, Li B, Jin Y, Hu X

OncoTargets and Therapy 2018, 11:4377-4386

Published Date: 27 July 2018

Study Protocol

Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer

Ding MN, Li Y, Yang Y, Zhu K, Che SL, Lin ZH, Chen LY

OncoTargets and Therapy 2018, 11:4367-4375

Published Date: 26 July 2018

Original Research

The role of lncRNA CASC2 on prognosis of malignant tumors: a meta-analysis and bioinformatics

Yu L, Chen S, Bao H, Zhang W, Liao M, Liang Q, Cheng X

OncoTargets and Therapy 2018, 11:4355-4365

Published Date: 25 July 2018

Original Research

18F-fluorodeoxyglucose positron emission tomography predicts lymph node responses to definitive chemoradiotherapy in esophageal squamous cell carcinoma patients

Zhu W, Zhang Y, Kong L, Huang Y, Zheng J, Wang R, Li M, Yu J

OncoTargets and Therapy 2018, 11:4345-4353

Published Date: 25 July 2018

Original Research

Polymorphism of IFN-γ+874T/A associated with production of IFN-γ affects human papillomavirus susceptibility in rural women from Luohe, Henan, China

Zhang QW, Song JY, Yu JH, Sun MZ, Tang SY, Yang SZ, Cao LJ, Wang HF, Cui LN, Fu XH

OncoTargets and Therapy 2018, 11:4339-4344

Published Date: 25 July 2018

Original Research

Identification of prognostic risk factors for esophageal adenocarcinoma using bioinformatics analysis

Dong Z, Wang J, Zhan T, Xu S

OncoTargets and Therapy 2018, 11:4327-4337

Published Date: 25 July 2018

Original Research

Endoplasmic reticulum stress-mediated autophagy contributes to 5-ethylamino-9-diethylaminobenzo[a]phenoselenazinium-mediated photodynamic therapy via the PERK–eIF2α pathway

Chen J, Huang JH, Wang Z, Song X, Chen Z, Zeng Q, Zhou X, Zuo Z, Zhao S, Chen X, Kang J

OncoTargets and Therapy 2018, 11:4315-4325

Published Date: 24 July 2018

Original Research

Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-κB, uPA activator, and MMP-9

Rajasinghe LD, Pindiprolu RH, Gupta SV

OncoTargets and Therapy 2018, 11:4301-4314

Published Date: 24 July 2018

Original Research

Analysis of change in microRNA expression profiles of lung cancer A549 cells treated with Radix tetrastigma hemsleyani flavonoids

Liu P, Yang X, Zhang H, Pu J, Wei K

OncoTargets and Therapy 2018, 11:4283-4300

Published Date: 24 July 2018

Original Research

Efficacy of bevacizumab versus epidermal growth factor receptor inhibitors for wild-type RAS metastatic colorectal cancer: a meta-analysis

Jiang W, Yu Q, Ning R, Zhao W, Wei C

OncoTargets and Therapy 2018, 11:4271-4281

Published Date: 24 July 2018

Review

Effects of miRNAs on functions of breast cancer stem cells and treatment of breast cancer

Zhang Y, Xu B, Zhang XP

OncoTargets and Therapy 2018, 11:4263-4270

Published Date: 24 July 2018

Original Research

Transcobalamin I: a novel prognostic biomarker of neoadjuvant chemotherapy in locally advanced hypopharyngeal squamous cell cancers

Wang Y, Yue C, Fang J, Gong L, Lian M, Wang R, Feng L, Ma H, Ma Z, Liu H

OncoTargets and Therapy 2018, 11:4253-4261

Published Date: 24 July 2018

Original Research

Comparable efficacy and less toxicity of pegylated liposomal doxorubicin versus epirubicin for neoadjuvant chemotherapy of breast cancer: a case-control study

Dong M, Luo L, Ying X, Lu X, Shen J, Jiang Z, Wang L

OncoTargets and Therapy 2018, 11:4247-4252

Published Date: 23 July 2018

Original Research

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients

Kim HJ, Jo MJ, Kim BR, Kim JL, Jeong YA, Na YJ, Park SH, Lee SY, Lee DH, Kim BH, Yoo YD, Oh SC

OncoTargets and Therapy 2018, 11:4233-4246

Published Date: 23 July 2018

Original Research

CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway

Jia Y, Xiao Z, Gongsun X, Xin Z, Shang B, Chen G, Wang Z, Jiang W

OncoTargets and Therapy 2018, 11:4221-4232

Published Date: 20 July 2018

Original Research

Matrix metalloproteinase-7 may serve as a novel biomarker for cervical cancer

Zhu L, Zheng X, Du Y, Xing Y, Xu K, Cui L

OncoTargets and Therapy 2018, 11:4207-4220

Published Date: 20 July 2018

Original Research

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells

Yang L, Xie N, Huang J, Huang H, Xu S, Wang Z, Cai J

OncoTargets and Therapy 2018, 11:4197-4206

Published Date: 19 July 2018

Original Research

Promoter methylation analysis of CDH1 and p14ARF genes in patients with urothelial bladder cancer

Bayramov B, Gunes S, Buyukalpelli R, Aydın O, Henkel R

OncoTargets and Therapy 2018, 11:4189-4196

Published Date: 19 July 2018

Original Research

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway

Ge H, Liang C, Li Z, An D, Ren S, Yue C, Wu J

OncoTargets and Therapy 2018, 11:4177-4187

Published Date: 19 July 2018

Original Research

Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis

Zheng T, Li D, He Z, Feng S, Zhao S

OncoTargets and Therapy 2018, 11:4167-4175

Published Date: 19 July 2018

Original Research

Expression of protein disulfide isomerase A3 precursor in colorectal cancer

Yang Z, Liu J, Shi Q, Chao Y, Di Y, Sun J, Zhang J, Huang L, Guo H, He C

OncoTargets and Therapy 2018, 11:4159-4166

Published Date: 19 July 2018

Original Research

Efficacy and safety assessment of apatinib in patients with advanced gastric cancer: a meta-analysis

Chen J, Wang J

OncoTargets and Therapy 2018, 11:4149-4158

Published Date: 19 July 2018

Review

Progress in the treatment of solid tumors with apatinib: a systematic review

Zhao D, Hou H, Zhang X

OncoTargets and Therapy 2018, 11:4137-4147

Published Date: 19 July 2018

Original Research

Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma

Xin Z, Xin G, Shi M, Song L, Wang Q, Jiang B, Liu X

OncoTargets and Therapy 2018, 11:4125-4136

Published Date: 19 July 2018

Review

Pleiotropic functions of miR107 in cancer networks

Luo Z, Zheng Y, Zhang W

OncoTargets and Therapy 2018, 11:4113-4124

Published Date: 18 July 2018

Original Research

Identification of potential core genes in triple negative breast cancer using bioinformatics analysis

Li MX, Jin LT, Wang TJ, Feng YJ, Pan CP, Zhao DM, Shao J

OncoTargets and Therapy 2018, 11:4105-4112

Published Date: 18 July 2018

Original Research

TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma

Yu S, Xu T, Dai J, Ma M, Tang H, Chi Z, Si L, Cui C, Sheng X, Kong Y, Guo J

OncoTargets and Therapy 2018, 11:4097-4104

Published Date: 17 July 2018

Original Research

miR-19b serves as a prognostic biomarker of breast cancer and promotes tumor progression through PI3K/AKT signaling pathway

Li C, Zhang J, Ma Z, Zhang F, Yu W

OncoTargets and Therapy 2018, 11:4087-4095

Published Date: 16 July 2018

Original Research

MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42

Gu G, Wang L, Zhang J, Wang H, Tan T, Zhang G

OncoTargets and Therapy 2018, 11:4075-4085

Published Date: 16 July 2018

Original Research

MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9)

Liu R, Wang F, Guo Y, Yang J, Chen S, Gao X, Wang X

OncoTargets and Therapy 2018, 11:4065-4073

Published Date: 16 July 2018

Review

New PDL1 inhibitors for non-small cell lung cancer: focus on pembrolizumab

Bylicki O, Paleiron N, Rousseau-Bussac G, Chouaïd C

OncoTargets and Therapy 2018, 11:4051-4064

Published Date: 16 July 2018

Case report

Long-term progression-free survival of third-line apatinib in lung squamous cell carcinoma

Li X, Li X, Fang X, Yuan Y

OncoTargets and Therapy 2018, 11:4047-4050

Published Date: 16 July 2018

Original Research

MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition

Hu F, Liu C, Xie F, Lin X, Yang J, Wang C, Huang Q

OncoTargets and Therapy 2018, 11:4035-4046

Published Date: 13 July 2018

Case report

Mutational analysis on gastric, duodenal, bone, and mediastinal lymph node metastases and blood from a case of primary lung adenocarcinoma

Yang X, Chen R, Wu C, Zhao W, Ji M

OncoTargets and Therapy 2018, 11:4029-4034

Published Date: 13 July 2018

Original Research

Downregulation and DNA methylation of ECRG4 in gastric cancer

Deng P, Chang XJ, Gao ZM, Xu XY, Sun AQ, Li K, Dai DQ

OncoTargets and Therapy 2018, 11:4019-4028

Published Date: 13 July 2018

Original Research

MFAP2 promotes epithelial–mesenchymal transition in gastric cancer cells by activating TGF-β/SMAD2/3 signaling pathway

Wang JK, Wang WJ, Cai HY, Du BB, Mai P, Zhang LJ, Ma W, Hu YG, Feng SF, Miao GY

OncoTargets and Therapy 2018, 11:4001-4017

Published Date: 12 July 2018

Original Research

The effect of tubeimoside-1 on the proliferation, metastasis and apoptosis of oral squamous cell carcinoma in vitro

Wu T, Cui H, Xu Y, Du Q, Zhao E, Cao J, Nie L, Fu G, Ren A

OncoTargets and Therapy 2018, 11:3989-4000

Published Date: 10 July 2018

Original Research

Overexpressed CDR1as functions as an oncogene to promote the tumor progression via miR-7 in non-small-cell lung cancer

Zhang X, Yang D, Wei Y

OncoTargets and Therapy 2018, 11:3979-3987

Published Date: 10 July 2018

Original Research

Increased expression of antisense lncRNA SPINT1-AS1 predicts a poor prognosis in colorectal cancer and is negatively correlated with its sense transcript

Li C, Li W, Zhang YL, Zhang X, Liu T, Zhang Y, Yang YM, Wang LL, Pan HW, Ji J, Wang CX

OncoTargets and Therapy 2018, 11:3969-3978

Published Date: 10 July 2018

Original Research

SIRT4 acts as a tumor suppressor in gastric cancer by inhibiting cell proliferation, migration, and invasion

Sun H, Huang D, Liu G, Jian F, Zhu J, Zhang L

OncoTargets and Therapy 2018, 11:3959-3968

Published Date: 10 July 2018

Original Research

Immunohistochemical expression of hormone receptors, Ki-67, endoglin (CD105), claudins 3 and 4, MMP -2 and -9 in endometrial polyps and endometrial cancer type I

Peres GF, Spadoto-Dias D, Bueloni-Dias FN, Leite NJ, Elias LV, Domingues MA, Padovani CR, Dias R

OncoTargets and Therapy 2018, 11:3949-3958

Published Date: 9 July 2018

Case report

Role of chemotherapy with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI ) rechallenge in small cell transformation after EGFR-TKI failure: a case report

Lee S, Joo JH, Kwak MA, Sohn K, Chon SH

OncoTargets and Therapy 2018, 11:3943-3947

Published Date: 9 July 2018

Original Research

Overexpression of DJ-1 correlates with aggressive clinicopathological characteristics and poor prognosis in malignant tumors: a meta-analysis

Wang Q, Li F, Shi W, Zhang Q, Wang J, Yan X, Chai L, Li M

OncoTargets and Therapy 2018, 11:3931-3942

Published Date: 9 July 2018

Original Research

Integrated omics and gene expression analysis identifies the loss of metabolite–metabolite correlations in small cell lung cancer

Yu L, Li K, Xu Z, Cui G, Zhang X

OncoTargets and Therapy 2018, 11:3919-3929

Published Date: 6 July 2018

Original Research

Predictive value of single nucleotide polymorphisms in XRCC1 for radiation-induced normal tissue toxicity

Zhao J, Zhi Z, Zhang M, Li Q, Li J, Wang X, Ma C

OncoTargets and Therapy 2018, 11:3901-3918

Published Date: 6 July 2018

Review

MicroRNAs as potential biomarkers for diagnosis, therapy and prognosis of gastric cancer

Yuan HL, Wang T, Zhang KH

OncoTargets and Therapy 2018, 11:3891-3900

Published Date: 6 July 2018

Original Research

The clinical usefulness of natural killer cell activity in patients with suspected or diagnosed prostate cancer: an observational cross-sectional study

Song W, Yu JW, Jeong BC, Seo SI, Jeon SS, Lee HM, Choi HY, Kang ES, Jeon HG

OncoTargets and Therapy 2018, 11:3883-3889

Published Date: 6 July 2018

Original Research

Bortezomib-based therapy for transplant-ineligible East Asian patients with newly diagnosed mantle-cell lymphoma

Jin J, Okamoto R, Yoon SS, Shih LY, Zhu J, Liu T, Hong XN, Pei L, Rooney B, van de Velde H, Huang HQ

OncoTargets and Therapy 2018, 11:3869-3882

Published Date: 6 July 2018

Original Research

Loss of miR-516a-3p mediates upregulation of ABCC5 in prostate cancer and drives its progression

Zhang H, Lian Z, Sun G, Liu R, Xu Y

OncoTargets and Therapy 2018, 11:3853-3867

Published Date: 6 July 2018

Review

The role of histone lysine methyltransferase NSD3 in cancer

Han X, Piao L, Zhuang Q, Yuan X, Liu Z, He X

OncoTargets and Therapy 2018, 11:3847-3852

Published Date: 5 July 2018

Original Research

miR-106b-5p inhibits the invasion and metastasis of colorectal cancer by targeting CTSA

Ni S, Weng W, Xu M, Wang Q, Tan C, Sun H, Wang L, Huang D, Du X, Sheng W

OncoTargets and Therapy 2018, 11:3835-3845

Published Date: 4 July 2018

Original Research

Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2

Wan B, Zang Y, Wang L

OncoTargets and Therapy 2018, 11:3827-3833

Published Date: 4 July 2018

Review

Tumor-associated macrophage-derived cytokines enhance cancer stem-like characteristics through epithelial–mesenchymal transition

Chen Y, Tan W, Wang C

OncoTargets and Therapy 2018, 11:3817-3826

Published Date: 4 July 2018

Original Research

Silencing of c-jun decreases cell migration, invasion, and EMT in radioresistant human nasopharyngeal carcinoma cell line CNE-2R

Lin G, Yu B, Liang Z, Li L, Qu S, Chen K, Zhou L, Lu Q, Sun Y, Zhu X

OncoTargets and Therapy 2018, 11:3805-3815

Published Date: 4 July 2018

Original Research

By blocking hexokinase-2 phosphorylation, limonin suppresses tumor glycolysis and induces cell apoptosis in hepatocellular carcinoma

Yao J, Liu J, Zhao W

OncoTargets and Therapy 2018, 11:3793-3803

Published Date: 3 July 2018

Original Research

A prospective study on neoadjuvant chemoradiotherapy plus anti-EGFR monoclonal antibody followed by surgery for locally advanced cervical cancer

Lu H, Wu Y, Liu X, Jiang H, Pang Q, Peng L, Cheng J, Deng S, Gu J, Zhao R, Hu X, Chen C, Yu J

OncoTargets and Therapy 2018, 11:3785-3792

Published Date: 2 July 2018

Original Research

SIL1 functions as an oncogene in glioma by AKT/mTOR signaling pathway

Xu H, Xu S, Zhang R, Xin T, Pang Q

OncoTargets and Therapy 2018, 11:3775-3783

Published Date: 2 July 2018

Original Research

Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer

Wang S, Zhang Z, Qian W, Ji D, Wang Q, Ji B, Zhang Y, Zhang C, Sun Y, Zhu C, Sun Y

OncoTargets and Therapy 2018, 11:3765-3774

Published Date: 2 July 2018

Review

Colorectal neoplasia differentially expressed: a long noncoding RNA with an imperative role in cancer

Dai M, Li S, Qin X

OncoTargets and Therapy 2018, 11:3755-3763

Published Date: 29 June 2018

Review

Primary effusion lymphoma: current perspectives

Narkhede M, Arora S, Ujjani C

OncoTargets and Therapy 2018, 11:3747-3754

Published Date: 28 June 2018

Review

IRX-2 natural cytokine biologic for immunotherapy in patients with head and neck cancers

Wolf GT, Moyer JS, Kaplan MJ, Newman JG, Egan JE, Berinstein NL, Whiteside TL

OncoTargets and Therapy 2018, 11:3731-3746

Published Date: 28 June 2018

Original Research

Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma

Dong M, Miao L, Zhang F, Li S, Han J, Yu R, Qie S

OncoTargets and Therapy 2018, 11:3721-3729

Published Date: 28 June 2018

Review

Updates on the clinical diagnosis and management of ocular sebaceous carcinoma: a brief review of the literature

Xu YF, Li F, Jia RB, Fan XQ

OncoTargets and Therapy 2018, 11:3713-3720

Published Date: 27 June 2018

Case report

Targeted therapy and immunotherapy for platinum-refractory advanced ovarian adenosquamous carcinoma: a case report

Li A, Sun S, Song T, Li X, Cheng W, Yao R, Zhang D, Cai Z, Zhang J, Zhai D, Yu C

OncoTargets and Therapy 2018, 11:3705-3711

Published Date: 27 June 2018

Original Research

Chemotherapy with or without pemetrexed as second-line regimens for advanced non-small-cell lung cancer patients who have progressed after first-line EGFR TKIs: a systematic review and meta-analysis

Li ZH, Guo HY, Lu YY, Hu JX, Luo HT, Gu WG

OncoTargets and Therapy 2018, 11:3697-3703

Published Date: 27 June 2018

Original Research

Impact of smoking on efficacy of PD-1/PD-L1 inhibitors in non-small cell lung cancer patients: a meta-analysis

Li B, Huang X, Fu L

OncoTargets and Therapy 2018, 11:3691-3696

Published Date: 26 June 2018

Case report

An uncommon granulocytic sarcoma of the breast: a case report and literature review

Zhai J, Kong X, Yang X, Gao J, Xuan L, Wang X, Wang J, Fang Y

OncoTargets and Therapy 2018, 11:3685-3690

Published Date: 25 June 2018

Original Research

CAT3, a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independently of O6-methylguanine DNA methyltransferase expression

Ji M, Wang L, Chen J, Xue N, Wang C, Lai F, Wang R, Yu SS, Jin J, Chen X

OncoTargets and Therapy 2018, 11:3671-3684

Published Date: 25 June 2018

Original Research

Prognostic impact of the number of lymph nodes examined in different stages of colorectal mucinous adenocarcinoma

Ma Y, Luo YQ, Lin N, Lv YZ, Zhou Y, Li B, Han KN, Jiang S, Gao JJ

OncoTargets and Therapy 2018, 11:3659-3670

Published Date: 25 June 2018

Original Research

lincROR influences the stemness and crizotinib resistance in EML–ALK+ non-small-cell lung cancer cells

Yang Y, Huang J, Xie N, Huang H, Xu S, Cai J, Qi S

OncoTargets and Therapy 2018, 11:3649-3657

Published Date: 22 June 2018

Original Research

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma

Wang H, Fang ZL, Zhang GH, Ma X

OncoTargets and Therapy 2018, 11:3637-3647

Published Date: 21 June 2018

Original Research

MYO5A inhibition by miR-145 acts as a predictive marker of occult neck lymph node metastasis in human laryngeal squamous cell carcinoma

Zhao X, Zhang W, Ji W

OncoTargets and Therapy 2018, 11:3619-3635

Published Date: 21 June 2018

Original Research

A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1

Zhao XZ, Wu XH

OncoTargets and Therapy 2018, 11:3609-3617

Published Date: 21 June 2018

Original Research

Whole-body MRI versus 18F-FDG PET/CT for pretherapeutic assessment and staging of lymphoma: a meta-analysis

Wang D, Huo Y, Chen S, Wang H, Ding Y, Zhu X, Ma C

OncoTargets and Therapy 2018, 11:3597-3608

Published Date: 20 June 2018

Original Research

lncRNA H19 predicts poor prognosis in patients with melanoma and regulates cell growth, invasion, migration and epithelial–mesenchymal transition in melanoma cells

Shi G, Li H, Gao F, Tan Q

OncoTargets and Therapy 2018, 11:3583-3595

Published Date: 20 June 2018

Original Research

Impact of RNA integrity and blood sample storage conditions on the gene expression analysis

Shen YT, Li R, Tian F, Chen ZZ, Lu N, Bai YF, Ge QY, Lu ZH

OncoTargets and Therapy 2018, 11:3573-3581

Published Date: 20 June 2018

Original Research

Clinicopathological and prognostic significance of FoxM1 in hepatocellular carcinoma patients: a meta-analysis

Liang C, Zhao J, Ge H, Li G, Wu J

OncoTargets and Therapy 2018, 11:3561-3571

Published Date: 19 June 2018

Original Research

The role of radioactive iodine therapy in papillary thyroid cancer: an observational study based on SEER

Tang J, Kong D, Cui Q, Wang K, Zhang D, Liao X, Gong Y, Wu G

OncoTargets and Therapy 2018, 11:3551-3560

Published Date: 19 June 2018

Original Research

Prognostic value of miR-17-5p in cancers: a meta-analysis

Kong W, Cheng Y, Liang H, Chen Q, Xiao C, Li K, Huang Z, Zhang J

OncoTargets and Therapy 2018, 11:3541-3549

Published Date: 19 June 2018

Review

Multiple biological functions of transcription factor 21 in the development of various cancers

Jiang X, Yang Z

OncoTargets and Therapy 2018, 11:3533-3539

Published Date: 19 June 2018

Original Research

Curcumin suppresses the progression of laryngeal squamous cell carcinoma through the upregulation of miR-145 and inhibition of the PI3K/Akt/mTOR pathway

Zhu X, Zhu R

OncoTargets and Therapy 2018, 11:3521-3531

Published Date: 19 June 2018

Original Research

The prognosis for patients with newly diagnosed glioblastoma receiving bevacizumab combination therapy: a meta-analysis

Liao KL, Huang S, Wu YP

OncoTargets and Therapy 2018, 11:3513-3520

Published Date: 19 June 2018

Review

Combined small-cell lung carcinoma

Qin J, Lu H

OncoTargets and Therapy 2018, 11:3505-3511

Published Date: 19 June 2018

Original Research

Association between common polymorphisms in ERCC gene and prognosis of osteosarcoma in patients treated with chemotherapy: a meta-analysis

Li C, Yu X, Guo D, Liu G, Zhang K, Teng Q, Lin H

OncoTargets and Therapy 2018, 11:3495-3504

Published Date: 18 June 2018

Original Research

Downregulation of ribophorin II suppresses tumor growth, migration, and invasion of nasopharyngeal carcinoma

Hong F, Li Y, Ni H, Li J

OncoTargets and Therapy 2018, 11:3485-3494

Published Date: 15 June 2018

Original Research

STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway

Wang N, He X, Zhou R, Jia G, Qiao Q

OncoTargets and Therapy 2018, 11:3475-3484

Published Date: 15 June 2018

Original Research

MALAT1 silencing suppresses prostate cancer progression by upregulating miR-1 and downregulating KRAS

Chang J, Xu W, Du X, Hou J

OncoTargets and Therapy 2018, 11:3461-3473

Published Date: 15 June 2018

Original Research

The association of pretreatment serum albumin with outcomes in bladder cancer: a meta-analysis

Li J, Cheng Y, Liu G, Ji Z

OncoTargets and Therapy 2018, 11:3449-3459

Published Date: 15 June 2018

Original Research

Comparison of the prognosis of neoadjuvant chemoradiotherapy treatment with surgery alone in esophageal carcinoma: a meta-analysis

Ma HF, Lv GX, Cai ZF, Zhang DH

OncoTargets and Therapy 2018, 11:3441-3447

Published Date: 14 June 2018

Original Research

Effectiveness of lomustine and bevacizumab in progressive glioblastoma: a meta-analysis

Song J, Xue YQ, Zhao MM, Xu P

OncoTargets and Therapy 2018, 11:3435-3439

Published Date: 13 June 2018

Review

Reformulating acute myeloid leukemia: liposomal cytarabine and daunorubicin (CPX-351) as an emerging therapy for secondary AML

Chen EC, Fathi AT, Brunner AM

OncoTargets and Therapy 2018, 11:3425-3434

Published Date: 12 June 2018

Original Research

Twenty-gene-based prognostic model predicts lung adenocarcinoma survival

Zhao K, Li Z, Tian H

OncoTargets and Therapy 2018, 11:3415-3424

Published Date: 12 June 2018

Original Research

Efficacy and safety of sorafenib versus apatinib in the treatment of intermediate and advanced hepatocellular carcinoma: a comparative retrospective study

Wang Y, Gou Q, Xu R, Chen X, Zhou Z

OncoTargets and Therapy 2018, 11:3407-3413

Published Date: 12 June 2018

Original Research

Identification of CD24 as a marker for tumorigenesis of melanoma

Tang MR, Guo JY, Wang D, Xu N

OncoTargets and Therapy 2018, 11:3401-3406

Published Date: 12 June 2018

Review

Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer

Huang G, Zhu G

OncoTargets and Therapy 2018, 11:3395-3400

Published Date: 11 June 2018

Original Research

Expression and functional characterization of FOXM1 in non-small cell lung cancer

Zhang Y, Qiao W, Shan L

OncoTargets and Therapy 2018, 11:3385-3393

Published Date: 11 June 2018

Original Research

Prognostic value of spleen tyrosine kinase in human solid tumors

Ni B, Li S, Liu Y, Huang Y, Li Z

OncoTargets and Therapy 2018, 11:3377-3384

Published Date: 8 June 2018

Original Research

Meta-analysis of segmentectomy versus wedge resection in stage IA non-small-cell lung cancer

Xue WF, Duan GC, Zhang XP, Zhang H, Zhao QT, Xin ZF

OncoTargets and Therapy 2018, 11:3369-3375

Published Date: 7 June 2018

Original Research

Effect of AQP-5 silencing by siRNA interference on chemosensitivity of breast cancer cells

Li X, Pei B, Wang H, Tang C, Zhu W, Jin F

OncoTargets and Therapy 2018, 11:3359-3368

Published Date: 6 June 2018

Original Research

Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics

Liu X, Weng Y, Liu P, Sui Z, Zhou L, Huang Y, Zhang L, Zhang Y, Tan X

OncoTargets and Therapy 2018, 11:3345-3357

Published Date: 6 June 2018

Original Research

Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer

Kobayashi K, Naoki K, Manabe T, Masuzawa K, Hasegawa H, Yasuda H, Kawada I, Soejima K, Betsuyaku T

OncoTargets and Therapy 2018, 11:3335-3343

Published Date: 6 June 2018

Original Research

Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling

Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y, Kan Q

OncoTargets and Therapy 2018, 11:3323-3333

Published Date: 6 June 2018

Original Research

Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway

Al-Obeed O, Vaali-Mohammed MA, Eldehna WM, Al-Khayal K, Mahmood A, Abdel-Aziz HA, Zubaidi A, Alafeefy A, Abdulla M, Ahmad R

OncoTargets and Therapy 2018, 11:3313-3322

Published Date: 5 June 2018

Original Research

Overexpression of CLEC3A promotes tumor progression and poor prognosis in breast invasive ductal cancer

Ni J, Peng Y, Yang F, Xi X, Huang X, He C

OncoTargets and Therapy 2018, 11:3303-3312

Published Date: 5 June 2018

Original Research

Effects of the combination of As2O3 and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1

Zhao C, Wang M, Liu Y, Liang YJ, Han L, Chen C

OncoTargets and Therapy 2018, 11:3293-3301

Published Date: 1 June 2018

Original Research

Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1

Chen Y, Zhang F, Zhao Y, He K, Zheng X, Pan Y, Shao D, Shang P, Yang Y, Zhang D, Xie Y, Yao X, Chen L, Li J, Zhang X

OncoTargets and Therapy 2018, 11:3281-3292

Published Date: 1 June 2018

Original Research

Association of VDR gene TaqI polymorphism with the susceptibility to prostate cancer in Asian population evaluated by an updated systematic meta-analysis

Chen L, Wei J, Zhang S, Lou Z, Wang X, Ren Y, Qi H, Xie Z, Chen Y, Chen F, Wu Q, Fan X, Xu H, Huang S, Weng G

OncoTargets and Therapy 2018, 11:3267-3280

Published Date: 31 May 2018

Original Research

A new apatinib microcrystal formulation enhances the effect of radiofrequency ablation treatment on hepatocellular carcinoma

Xie H, Tian S, Yu H, Yang X, Liu J, Wang H, Feng F, Guo Z

OncoTargets and Therapy 2018, 11:3257-3265

Published Date: 31 May 2018

Review

Prognostic role of plasma mammaglobin A expression in breast carcinoma patients: a meta-analysis

Hu YY, Liu P, Wu D, Jiang YH

OncoTargets and Therapy 2018, 11:3245-3255

Published Date: 30 May 2018

Original Research

Prognostic significance of galectin-1 and vasculogenic mimicry in patients with gastric cancer

You X, Wang Y, Wu J, Liu Q, Chen D, Tang D, Wang D

OncoTargets and Therapy 2018, 11:3237-3244

Published Date: 29 May 2018

Original Research

Association between KIF1B (rs17401966) polymorphism and hepatocellular carcinoma susceptibility: a meta-analysis

Zhang Y, Zeng X, Lu H, Ji H, Lu L, Liu P, Hong R, Li Y

OncoTargets and Therapy 2018, 11:3225-3235

Published Date: 29 May 2018

Original Research

Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression

Li S, Wen D, Che S, Cui Z, Sun Y, Ren H, Hao J

OncoTargets and Therapy 2018, 11:3215-3223

Published Date: 6 June 2018

Original Research

Periostin overexpression is associated with worse prognosis in nasopharyngeal carcinoma from endemic area: a cohort study

Wei YC, Yang SF, Chang SL, Chen TJ, Lee SW, Chen HS, Lin LC, Li CF

OncoTargets and Therapy 2018, 11:3205-3213

Published Date: 29 May 2018

Original Research

Knockdown of KIF26B inhibits breast cancer cell proliferation, migration, and invasion

Gu S, Liang H, Qi D, Mao L, Mao G, Qian L, Zhang S

OncoTargets and Therapy 2018, 11:3195-3203

Published Date: 29 May 2018

Review

Emerging role of long non-coding RNAs in cisplatin resistance

Hu Y, Zhu QN, Deng JL, Li ZX, Wang G, Zhu YS

OncoTargets and Therapy 2018, 11:3185-3194

Published Date: 28 May 2018

Case report

A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature

Duan M, Xing H, Wang K, Niu C, Jiang C, Zhang L, Ezzat S, Zhang L

OncoTargets and Therapy 2018, 11:3179-3184

Published Date: 28 May 2018

Review

Recent advances on the progressive mechanism and therapy in castration-resistant prostate cancer

Wang K, Ruan H, Xu T, Liu L, Liu D, Yang H, Zhang X, Chen K

OncoTargets and Therapy 2018, 11:3167-3178

Published Date: 28 May 2018

Original Research

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells

Wang Z, Luo C, Wang H, Yan X, Liu W, Meng Z

OncoTargets and Therapy 2018, 11:3159-3166

Published Date: 28 May 2018

Original Research

High SRPX2 protein expression predicts unfavorable clinical outcome in patients with prostate cancer

Zhang M, Li X, Fan Z, Zhao J, Liu S, Zhang M, Li H, Goscinski MA, Fan H, Suo Z

OncoTargets and Therapy 2018, 11:3149-3157

Published Date: 28 May 2018

Original Research

miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells

Chen K, Chen Y, Chen Z, Shi Y, He Z, Ding B, Wang C, Yu L

OncoTargets and Therapy 2018, 11:3141-3147

Published Date: 25 May 2018

Original Research

Construction of a specific SVM classifier and identification of molecular markers for lung adenocarcinoma based on lncRNA-miRNA-mRNA network

Zhao J, Cheng W, He X, Liu Y, Li J, Sun J, Li J, Wang F, Gao Y

OncoTargets and Therapy 2018, 11:3129-3140

Published Date: 25 May 2018

Original Research

The incidence and predictors of symptomatic venous thromboembolism associated with peripherally inserted central catheters in patients with nasopharyngeal carcinoma

Liang YJ, He Y, Li JM, Chen LM, Chen LP, Wang C, Ji L, Li ZX, Tang LQ, Chen QY, Fan YY, Hu W

OncoTargets and Therapy 2018, 11:3119-3127

Published Date: 25 May 2018

Original Research

Overexpression of MCPH1 inhibits the migration and invasion of lung cancer cells

Wu X, Liu W, Liu X, Ai Q, Yu J

OncoTargets and Therapy 2018, 11:3111-3117

Published Date: 25 May 2018

Original Research

Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma

Lin MH, Lv D, Zheng YL, Wu ML, Xu C, Zhang Q, Wu LH

OncoTargets and Therapy 2018, 11:3101-3110

Published Date: 25 May 2018

Original Research

Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis

Liu X, Zhao Y, Zhang W, Gao Y, Huo M, Liu M, Xiao Z, Liang S, Xu N, Zhu H

OncoTargets and Therapy 2018, 11:3087-3100

Published Date: 24 May 2018

Original Research

An integrated analysis of key microRNAs, regulatory pathways and clinical relevance in bladder cancer

Li D, Hao X, Song Y

OncoTargets and Therapy 2018, 11:3075-3085

Published Date: 24 May 2018

Original Research

Gene expression and prognosis of NOX family members in gastric cancer

You X, Ma M, Hou G, Hu Y, Shi X

OncoTargets and Therapy 2018, 11:3065-3074

Published Date: 24 May 2018

Original Research

Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic colorectal cancer

Cicero G, De Luca R, Dieli F

OncoTargets and Therapy 2018, 11:3059-3063

Published Date: 24 May 2018

Original Research

The synergistic effects of Apatinib combined with cytotoxic chemotherapeutic agents on gastric cancer cells and in a fluorescence imaging gastric cancer xenograft model

Feng JH, Qin SK

OncoTargets and Therapy 2018, 11:3047-3057

Published Date: 24 May 2018

Original Research

High expression of USP22 predicts poor prognosis and advanced clinicopathological features in solid tumors: a meta-analysis

Yang XH, Zang H, Luo Y, Wu J, Fang Z, Zhu W, Li Y

OncoTargets and Therapy 2018, 11:3035-3046

Published Date: 23 May 2018

Original Research

LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway

Ke J, Ma P, Chen J, Qin J, Qian H

OncoTargets and Therapy 2018, 11:3025-3033

Published Date: 22 May 2018

Original Research

Expression of HSP90AA1/HSPA8 in hepatocellular carcinoma patients with depression

Xiang X, You XM, Li LQ

OncoTargets and Therapy 2018, 11:3013-3023

Published Date: 22 May 2018

Review

The role of HIF-1α in chemo-/radioresistant tumors

Xia Y, Jiang L, Zhong T

OncoTargets and Therapy 2018, 11:3003-3011

Published Date: 22 May 2018

Original Research

The methylation profiles of PRDM promoters in non–small cell lung cancer

Tan SX, Hu RC, Xia Q, Tan YL, Liu JJ, Gan GX, Wang LL

OncoTargets and Therapy 2018, 11:2991-3002

Published Date: 22 May 2018

Original Research

Resveratrol inhibits the proliferation of A549 cells by inhibiting the expression of COX-2

Li X, Li F, Wang FF, Li JF, Lin CZ, Du JX

OncoTargets and Therapy 2018, 11:2981-2989

Published Date: 22 May 2018

Original Research

Intra-arterial chemotherapy improved survival of stage 2–3 gallbladder cancer after curative resection

Chen C, Feng W, Zheng Y, Bao Y, Feng M

OncoTargets and Therapy 2018, 11:2975-2979

Published Date: 22 May 2018

Original Research

Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma

Liu J, Wu Q, Wang Y, Wei Y, Wu H, Duan L, Zhang Q, Wu Y

OncoTargets and Therapy 2018, 11:2963-2973

Published Date: 22 May 2018

Original Research

Downregulation of STARD8 in gastric cancer and its involvement in gastric cancer progression

Zhang S, Chang X, Ma J, Chen J, Zhi Y, Li Z, Dai D

OncoTargets and Therapy 2018, 11:2955-2961

Published Date: 21 May 2018

Original Research

Triclosan treatment decreased the antitumor effect of sorafenib on hepatocellular carcinoma cells

Wu M, Zhao G, Zhuang X, Zhang T, Zhang C, Zhang W, Zhang Z

OncoTargets and Therapy 2018, 11:2945-2954

Published Date: 18 May 2018

Original Research

Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells

Li Z, Zhu C, An B, Chen Y, He X, Qian L, Lan L, Li S

OncoTargets and Therapy 2018, 11:2937-2944

Published Date: 18 May 2018

Original Research

Downregulation of PDIA3 inhibits proliferation and invasion of human acute myeloid leukemia cells

Ye Q, Fu P, Dou J, Wang N

OncoTargets and Therapy 2018, 11:2925-2935

Published Date: 17 May 2018

Original Research

miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R

Liu N, Yang H, Wang H

OncoTargets and Therapy 2018, 11:2911-2923

Published Date: 17 May 2018

Original Research

High neutrophil to lymphocyte ratio and decreased CD69+NK cells represent a phenotype of high risk in early-stage breast cancer patients

Mandó P, Rizzo M, Roberti MP, Juliá EP, Pampena MB, Pérez de la Puente C, Loza CM, Ponce C, Nadal J, Coló FA, Mordoh J, Levy EM

OncoTargets and Therapy 2018, 11:2901-2910

Published Date: 17 May 2018

Original Research

Bacillus Calmette–Guérin and anti-PD-L1 combination therapy boosts immune response against bladder cancer

Wang Y, Liu J, Yang X, Liu Y, Liu Y, Li Y, Sun L, Yang X, Niu H

OncoTargets and Therapy 2018, 11:2891-2899

Published Date: 16 May 2018

Original Research

RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway

Li C, Jiang X, Lin B, Hong H, Zhu S, Jiang L, Wang X, Tang N, She F, Chen Y

OncoTargets and Therapy 2018, 11:2875-2890

Published Date: 16 May 2018

Review

Leaflet manual of external beam radiation therapy for hepatocellular carcinoma: a review of the indications, evidences, and clinical trials

Rim CH, Yoon WS

OncoTargets and Therapy 2018, 11:2865-2874

Published Date: 16 May 2018

Original Research

circSMAD2 inhibits the epithelial–mesenchymal transition by targeting miR-629 in hepatocellular carcinoma

Zhang XW, Luo P, Jing W, Zhou H, Liang CZ, Tu JC

OncoTargets and Therapy 2018, 11:2853-2863

Published Date: 16 May 2018

Original Research

NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation

Li T, Sun R, Lu MD, Chang J, Meng X, Wu H

OncoTargets and Therapy 2018, 11:2843-2852

Published Date: 15 May 2018

Review

Advances of exosome in the development of ovarian cancer and its diagnostic and therapeutic prospect

Shen J, Zhu X, Fei J, Shi P, Yu S, Zhou J

OncoTargets and Therapy 2018, 11:2831-2841

Published Date: 15 May 2018

Original Research

Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis

Zhou X, Huang X, Liang S, Tang S, Wu S, Huang T, Mo Z, Wang Q

OncoTargets and Therapy 2018, 11:2815-2830

Published Date: 15 May 2018

Original Research

5-Azacytidine treatment induces demethylation of DAPK1 and MGMT genes and inhibits growth in canine mammary gland tumor cells

Ren XL, Li HT, Song XY, Wu YH, Liu Y

OncoTargets and Therapy 2018, 11:2805-2813

Published Date: 15 May 2018

Original Research

Long noncoding RNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression

Diao L, Wang S, Sun Z

OncoTargets and Therapy 2018, 11:2797-2804

Published Date: 14 May 2018

Original Research

Impact of targeting transforming growth factor β-2 with antisense OT-101 on the cytokine and chemokine profile in patients with advanced pancreatic cancer

D'Cruz OJ, Qazi S, Hwang L, Ng K, Trieu V

OncoTargets and Therapy 2018, 11:2779-2796

Published Date: 14 May 2018

Original Research

Peritoneal carcinomatosis index as a predictor of diaphragmatic involvement in stage III and IV ovarian cancer

Llueca A, Serra A, Herraiz JL, Rivadulla I, Gomez-Quiles L, Gilabert-Estelles J, Escrig J

OncoTargets and Therapy 2018, 11:2771-2777

Published Date: 15 May 2018

Original Research

ZNF418 overexpression protects against gastric carcinoma and prompts a good prognosis

Hui H, Hu Z, Jiang C, Wu J, Gao Y, Wang X

OncoTargets and Therapy 2018, 11:2763-2770

Published Date: 11 May 2018

Original Research

Upregulation of circ_0066444 promotes the proliferation, invasion, and migration of gastric cancer cells

Rong D, Dong C, Fu K, Wang H, Tang W, Cao H

OncoTargets and Therapy 2018, 11:2753-2761

Published Date: 11 May 2018

Original Research

Leucine-rich alpha-2-glycoprotein-1 is up-regulated in colorectal cancer and is a tumor promoter

Zhang Q, Huang R, Tang Q, Yu Y, Huang Q, Chen Y, Wang G, Wang X

OncoTargets and Therapy 2018, 11:2745-2752

Published Date: 11 May 2018

Original Research

Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo

Ling Z, Guan H, You Z, Wang C, Hu L, Zhang L, Wang Y, Chen S, Xu B, Chen M

OncoTargets and Therapy 2018, 11:2735-2743

Published Date: 11 May 2018

Original Research

Association between angiogenesis and cytotoxic signatures in the tumor microenvironment of gastric cancer

Feng Y, Dai Y, Gong Z, Cheng JN, Zhang L, Sun C, Zeng X, Jia Q, Zhu B

OncoTargets and Therapy 2018, 11:2725-2733

Published Date: 10 May 2018

Original Research

Association between NR5A2 and the risk of pancreatic cancer, especially among Caucasians: a meta-analysis of case–control studies

Chen Q, Yuan H, Shi GD, Wu Y, Liu D, Lin YT, Chen L, Ge W, Jiang K, Miao Y

OncoTargets and Therapy 2018, 11:2709-2723

Published Date: 9 May 2018

Original Research

Clinical relevance of lysyl oxidase-like 2 and functional mechanisms in glioma

Du XG, Zhu MJ

OncoTargets and Therapy 2018, 11:2699-2708

Published Date: 9 May 2018

Original Research

Traditional Chinese medicine Astragalus polysaccharide enhanced antitumor effects of the angiogenesis inhibitor apatinib in pancreatic cancer cells on proliferation, invasiveness, and apoptosis

Wu J, Wang J, Su Q, Ding W, Li T, Yu J, Cao B

OncoTargets and Therapy 2018, 11:2685-2698

Published Date: 9 May 2018

Original Research

Delivery of bevacizumab by intracranial injection: assessment in glioma model

Liu YX, Liu WJ, Zhang HR, Zhang ZW

OncoTargets and Therapy 2018, 11:2673-2683

Published Date: 8 May 2018

Original Research

Influence of different ex vivo cell culture methods on the proliferation and anti-tumor activity of cytokine-induced killer cells from gastric cancer patients

Shi B, Sun AX, Zhang XR

OncoTargets and Therapy 2018, 11:2657-2672

Published Date: 8 May 2018

Original Research

Effect of first-line endocrine therapy in patients with hormone-sensitive advanced breast cancer: a network meta-analysis

Zhang T, Feng F, Zhao W, Tian J, Yao Y, Zhou C, Dong S, Wang C, Zang C, Lv Q, Sun C

OncoTargets and Therapy 2018, 11:2647-2656

Published Date: 8 May 2018

Original Research

The utilization of next-generation sequencing to detect somatic mutations and predict clinical prognosis of Chinese non-small cell lung cancer patients

Cao L, Long L, Li M, Yang H, Deng P, Mao X, Xiang J, Li B, Zhang T, Hu C

OncoTargets and Therapy 2018, 11:2637-2646

Published Date: 8 May 2018

Original Research

Predicting initial margin status in breast cancer patients during breast-conserving surgery

Pan Z, Zhu L, Li Q, Lai J, Peng J, Su F, Li S, Chen K

OncoTargets and Therapy 2018, 11:2627-2635

Published Date: 8 May 2018

Review

Are ovarian cancer stem cells the target for innovative immunotherapy?

Wang L, Xu T, Cui M

OncoTargets and Therapy 2018, 11:2615-2626

Published Date: 8 May 2018

Original Research

A 5-serum miRNA panel for the early detection of colorectal cancer

Guo S, Zhang J, Wang B, Zhang B, Wang X, Huang L, Liu H, Jia B

OncoTargets and Therapy 2018, 11:2603-2614

Published Date: 8 May 2018

Original Research

Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells

Wu S, Yang Y, Li F, Huang L, Han Z, Wang G, Yu H, Li H

OncoTargets and Therapy 2018, 11:2593-2601

Published Date: 8 May 2018

Original Research

WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling

Han Q, Kremerskothen J, Lin X, Zhang X, Rong X, Zhang D, Wang E

OncoTargets and Therapy 2018, 11:2581-2591

Published Date: 8 May 2018

Original Research

Partial stereotactic ablative boost radiotherapy in bulky non-small cell lung cancer: a retrospective study

Bai Y, Gao XS, Qin SB, Chen JY, Su MM, Liu Q, Qin XB, Ma MW, Zhao B, Gu XB, Xie M, Cui M, Qi X, Li XY

OncoTargets and Therapy 2018, 11:2571-2579

Published Date: 8 May 2018

Case Series

Fatal hemoptysis in patients with advanced esophageal cancer treated with apatinib

Wang W, Zhang L, Xie Y, Zhen TC, Su GZ, Zang Q

OncoTargets and Therapy 2018, 11:2565-2570

Published Date: 7 May 2018

Case report

Perioperative chemotherapy with pemetrexed and cisplatin for pulmonary large-cell neuroendocrine carcinoma: a case report and literature review

Tang H, Wang HY, Xi SY, He CY, Chang YX, Wang QM, Wu YF

OncoTargets and Therapy 2018, 11:2557-2563

Published Date: 7 May 2018

Original Research

Patterns of local failures and suggestions for reduction of clinical target volume for nasopharyngeal carcinoma patients without cervical lymph node metastasis

Li Y, Ou X, Shen C, Xu T, Li W, Hu C

OncoTargets and Therapy 2018, 11:2545-2555

Published Date: 7 May 2018

Original Research

Prognostic factors for operable biliary tract cancer: serum levels of lactate dehydrogenase, a strong association with survival

Ma L, Qiu JR, Zhang YD, Qiu TZ, Wang B, Chen WS, Li X, Sun J, Wang K, Li XC, Gu YH, Shu YQ, Chen XF

OncoTargets and Therapy 2018, 11:2533-2543

Published Date: 4 May 2018

Original Research

Low circulating total adiponectin, especially its non-high-molecular weight fraction, represents a promising risk factor for colorectal cancer: a meta-analysis

Lu W, Huang Z, Li N, Liu H

OncoTargets and Therapy 2018, 11:2519-2531

Published Date: 4 May 2018

Original Research

Clinical and radiological characteristics of central pulmonary adenocarcinoma: a comparison with central squamous cell carcinoma and small cell lung cancer and the impact on treatment response

Wang Z, Li M, Huang Y, Ma L, Zhu H, Kong L, Yu J

OncoTargets and Therapy 2018, 11:2509-2517

Published Date: 4 May 2018

Original Research

The genetic association between iNOS and eNOS polymorphisms and gastric cancer risk: a meta-analysis

Zhu Y, Jiang HG, Chen ZH, Lu BH, Li J, Peng YP, Shen XN

OncoTargets and Therapy 2018, 11:2497-2507

Published Date: 3 May 2018

Original Research

Pretreatment hematologic markers as prognostic predictors of gastroenteropancreatic neuroendocrine tumors: a systematic review and meta-analysis

Zhou Y, Li D, Lin Y, Yu M, Lu X, Jian Z, Na N, Hou B

OncoTargets and Therapy 2018, 11:2489-2496

Published Date: 1 May 2018

Original Research

UCA1 promotes cell proliferation and invasion and inhibits apoptosis through regulation of the miR129–SOX4 pathway in renal cell carcinoma

Liu Q, Li Y, Lv W, Zhang G, Tian X, Li X, Cheng H, Zhu C

OncoTargets and Therapy 2018, 11:2475-2487

Published Date: 1 May 2018

Original Research

Rechallenge of oxaliplatin-containing regimens in the third- or later-line therapy for patients with heavily treated metastatic colorectal cancer

Yang Q, Huang YY, Jiang ZM, Wang HZ, Li WY, Zhang B, Xie DR

OncoTargets and Therapy 2018, 11:2467-2473

Published Date: 1 May 2018

Original Research

Comprehensive analysis of a long noncoding RNA-associated competing endogenous RNA network in colorectal cancer

Fan Q, Liu B

OncoTargets and Therapy 2018, 11:2453-2466

Published Date: 1 May 2018

Original Research

The CXCL12 rs1801157 polymorphism and risk of colorectal cancer: a meta-analysis

Xu K, Dai H, Wang S, Zhang J, Liu T

OncoTargets and Therapy 2018, 11:2445-2452

Published Date: 1 May 2018

Case report

A favorable outcome of advanced dermatofibrosarcoma protuberans under treatment with sunitinib after imatinib failure

Xiao W, Que Y, Peng RQ, Ding Y, Zhao JJ, Wen XZ, Weng DS, Zhang XS, Guan YX, Zhang X

OncoTargets and Therapy 2018, 11:2439-2443

Published Date: 1 May 2018

Original Research

Role of miR-613 as a tumor suppressor in glioma cells by targeting SOX9

Sang S, Liu X, Sun D

OncoTargets and Therapy 2018, 11:2429-2438

Published Date: 30 April 2018

Review

A meta-analytic review of the association between two common SNPs in miRNAs and lung cancer susceptibility

Xiao S, Sun S, Long W, Kuang S, Liu Y, Huang H, Zhou J, Zhou Y, Lu X

OncoTargets and Therapy 2018, 11:2419-2427

Published Date: 30 April 2018

Original Research

Peptide SA12 inhibits proliferation of breast cancer cell lines MCF-7 and MDA-MB-231 through G0/G1 phase cell-cycle arrest

Yang LF, Liu HR, Long M, Wang X, Lin F, Gao ZW, Zhang HZ

OncoTargets and Therapy 2018, 11:2409-2417

Published Date: 30 April 2018

Clinical Trial Report

A Phase Ib study of ruxolitinib + gemcitabine ± nab-paclitaxel in patients with advanced solid tumors

Bauer TM, Patel MR, Forero-Torres A, George TJ Jr, Assad A, Du Y, Hurwitz H

OncoTargets and Therapy 2018, 11:2399-2407

Published Date: 30 April 2018

Original Research

Role of Beclin1 expression in patients with hepatocellular carcinoma: a meta-analysis

Liang C, Li W, Ge H, Zhang KT, Li GM, Wu J

OncoTargets and Therapy 2018, 11:2387-2397

Published Date: 27 April 2018

Original Research

MicroRNA-328 inhibits migration and epithelial–mesenchymal transition by targeting CD44 in nasopharyngeal carcinoma cells

Lin CH, Chiang MC, Chen YJ

OncoTargets and Therapy 2018, 11:2375-2385

Published Date: 27 April 2018

Original Research

LDH-A promotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer

Zhang Y, Lin S, Chen Y, Yang F, Liu S

OncoTargets and Therapy 2018, 11:2363-2373

Published Date: 27 April 2018

Original Research

Retrospective study of survival in human papillomavirus-negative oropharyngeal squamous cell carcinoma treated with primary surgery and associated prognostic factors

Yuan Y, Wang L, Li QX, Zhang JY, Xu ZX, Guo CB

OncoTargets and Therapy 2018, 11:2355-2362

Published Date: 27 April 2018

Original Research

The effect of icotinib combined with chemotherapy in untreated non-small-cell lung cancer that harbored EGFR-sensitive mutations in a real-life setting: a retrospective analysis

Wang LL, Li Y, Li LC, Wu ZJ, Yang D, Ma HW, Wang DL

OncoTargets and Therapy 2018, 11:2345-2353

Published Date: 26 April 2018

Original Research

Combination of long noncoding RNA MALAT1 and carcinoembryonic antigen for the diagnosis of malignant pleural effusion caused by lung cancer

Wang WW, Zhou XL, Song YJ, Yu CH, Zhu WG, Tong YS

OncoTargets and Therapy 2018, 11:2333-2344

Published Date: 24 April 2018

Original Research

MicroRNA-150 suppresses triple-negative breast cancer metastasis through targeting HMGA2

Tang W, Xu P, Wang H, Niu Z, Zhu D, Lin Q, Tang L, Ren L

OncoTargets and Therapy 2018, 11:2319-2332

Published Date: 24 April 2018

Original Research

Risk factors for esophageal fistula in patients with locally advanced esophageal carcinoma receiving chemoradiotherapy

Zhang Y, Li Z, Zhang W, Chen W, Song Y

OncoTargets and Therapy 2018, 11:2311-2317

Published Date: 23 April 2018

Case report

Effectiveness of afatinib after ineffectiveness of gefitinib in an advanced lung adenocarcinoma patient with a single EGFR exon 20 S768I mutation: a case report

Duan H, Peng Y, Cui H, Qiu Y, Li Q, Zhang J, Shen W, Sun C, Luo C

OncoTargets and Therapy 2018, 11:2303-2309

Published Date: 23 April 2018

Case report

Neuroendocrine tumor of the common bile duct: a case report and review of the literature

Liu Z, Zhang DY, Lu Z, Zhang P, Sun WL, Ma X, Wu H, Wu BQ, Zhou S

OncoTargets and Therapy 2018, 11:2295-2301

Published Date: 23 April 2018

Review

Forodesine in the treatment of relapsed/refractory peripheral T-cell lymphoma: an evidence-based review

Makita S, Maeshima AM, Maruyama D, Izutsu K, Tobinai K

OncoTargets and Therapy 2018, 11:2287-2293

Published Date: 20 April 2018

Original Research

Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients

Chen Q, Li R, Zhang Z, Deng Q, Li K, Wang H, Yang X, Wu Y

OncoTargets and Therapy 2018, 11:2279-2286

Published Date: 20 April 2018

Corrigendum

Modulation of human melanoma cell proliferation and apoptosis by hydatid cyst fluid of Echinococcus granulosus [Corrigendum]

Gao XY, Zhang GH, Huang L

OncoTargets and Therapy 2018, 11:2277-2278

Published Date: 30 April 2018

Original Research

Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67

Xu J, Guo X, Jing M, Sun T

OncoTargets and Therapy 2018, 11:2269-2275

Published Date: 19 April 2018

Original Research

Role of DiGeorge syndrome critical region gene 9, a long noncoding RNA, in gastric cancer

Ni C, Yang P, Guo J, Ye M

OncoTargets and Therapy 2018, 11:2259-2267

Published Date: 19 April 2018

Original Research

Evidence from an updated meta-analysis of the prognostic impacts of postoperative radiotherapy and chemotherapy in patients with anaplastic thyroid carcinoma

Xia Q, Wang W, Xu J, Chen X, Zhong Z, Sun C

OncoTargets and Therapy 2018, 11:2251-2257

Published Date: 19 April 2018

Original Research

Cardiotoxic effects of the novel approved anti-ErbB2 agents and reverse cardioprotective effects of ranolazine

De Lorenzo C, Paciello R, Riccio G, Rea D, Barbieri A, Coppola C, Maurea N

OncoTargets and Therapy 2018, 11:2241-2250

Published Date: 19 April 2018

Original Research

microRNA-26a induces a mitochondrial apoptosis mediated by p53 through targeting to inhibit Mcl1 in human hepatocellular carcinoma

Gao X, Zhu Y, Li JH, Wang X, Zhang X, Yi C, Yang X

OncoTargets and Therapy 2018, 11:2227-2239

Published Date: 19 April 2018

Original Research

EGFR, KRAS, BRAF, PTEN, and PIK3CA mutation in plasma of small cell lung cancer patients

Lu HY, Qin J, Han N, Lei L, Xie F, Li C

OncoTargets and Therapy 2018, 11:2217-2226

Published Date: 20 April 2018

Original Research

miR-488 inhibits cell growth and metastasis in renal cell carcinoma by targeting HMGN5

Wei X, Yu L, Kong X

OncoTargets and Therapy 2018, 11:2205-2216

Published Date: 18 April 2018

Erratum

MicroRNA 302b-3p/302c-3p/302d-3p inhibits epithelial–mesenchymal transition and promotes apoptosis in human endometrial carcinoma cells [Erratum]

Li Y, Huo J, Pan X, Wang C, Ma X

OncoTargets and Therapy 2018, 11:2203-2204

Published Date: 17 April 2018

Original Research

miR-30a suppresses osteosarcoma proliferation and metastasis by downregulating MEF2D expression

Du L, Chen T, Zhao K, Yang D

OncoTargets and Therapy 2018, 11:2195-2202

Published Date: 17 April 2018

Review

The role of Hippo signal pathway in breast cancer metastasis

Wei C, Wang Y, Li X

OncoTargets and Therapy 2018, 11:2185-2193

Published Date: 17 April 2018

Original Research

Overexpression of HDAC9 is associated with poor prognosis and tumor progression of breast cancer in Chinese females

Huang Y, Jian W, Zhao J, Wang G

OncoTargets and Therapy 2018, 11:2177-2184

Published Date: 17 April 2018

Original Research

Preoperative apolipoprotein B/apolipoprotein A1 ratio: a novel prognostic factor for gastric cancer

Ma MZ, Yuan SQ, Chen Y, Zhou ZW

OncoTargets and Therapy 2018, 11:2169-2176

Published Date: 13 April 2018

Original Research

Prognostic and clinicopathological value of SIRT3 expression in various cancers: a systematic review and meta-analysis

Zhou Y, Cheng S, Chen S, Zhao Y

OncoTargets and Therapy 2018, 11:2157-2167

Published Date: 13 April 2018

Original Research

Multiple treatment modalities for brain metastasis in patients with EGFR-mutant non-small-cell lung cancer

Wang HY, Yu X, Fan Y, Jiang Y

OncoTargets and Therapy 2018, 11:2149-2155

Published Date: 13 April 2018

Review

Profile of apalutamide in the treatment of metastatic castration-resistant prostate cancer: evidence to date

Chong JT, Oh WK, Liaw BC

OncoTargets and Therapy 2018, 11:2141-2147

Published Date: 12 April 2018

Original Research

Albumin/globulin ratio is negatively correlated with PD-1 and CD25 mRNA levels in breast cancer patients

Liu C, Wang W, Meng XY, Sun B, Cong Y, Liu JN, Wang Q, Liu GX, Wu SK

OncoTargets and Therapy 2018, 11:2131-2139

Published Date: 12 April 2018

Review

Efficacy of pemetrexed-based regimens in advanced non–small cell lung cancer patients with activating epidermal growth factor receptor mutations after tyrosine kinase inhibitor failure: a systematic review

Han BH, Yang LL, Wang X, Yao LD

OncoTargets and Therapy 2018, 11:2121-2129

Published Date: 12 April 2018

Original Research

Overexpression of high mobility group box 1 contributes to progressive clinicopathological features and poor prognosis of human bladder urothelial carcinoma

Huang CK, Huang ZC, Zhao XK, Wang YH, Zhao HQ, Zhong ZH, Wang L

OncoTargets and Therapy 2018, 11:2111-2120

Published Date: 12 April 2018

Original Research

Small ubiquitin-like modifier 1 modification of pyruvate kinase M2 promotes aerobic glycolysis and cell proliferation in A549 human lung cancer cells

An S, Huang L, Miao P, Shi L, Shen M, Zhao X, Liu J, Huang G

OncoTargets and Therapy 2018, 11:2097-2109

Published Date: 13 April 2018

Original Research

Four cycles of adriamycin and cyclophosphamide followed by four cycles of docetaxel (NSABP-B27) with concomitant trastuzumab as neoadjuvant therapy for high-risk, early-stage, HER2-positive breast cancer patients

Abdel-Razeq H, Saadeh SS, Abu-Nasser M, Abdulelah H, Marie L, Salam M, Al-Haj Ali B, Ibrahim M, Rimawi D

OncoTargets and Therapy 2018, 11:2091-2096

Published Date: 11 April 2018

Original Research

Investigation of LEP and LEPR polymorphisms with the risk of hepatocellular carcinoma: a case–control study in Eastern Chinese Han population

Zhang S, Jiang J, Chen Z, Wang Y, Tang W, Liu C, Liu L, Chen Y

OncoTargets and Therapy 2018, 11:2083-2089

Published Date: 11 April 2018

Original Research

Expression of pyruvate kinase M2 in human bladder cancer and its correlation with clinical parameters and prognosis

Huang CK, Huang ZC, Bai PM, Luo GC, Zhao XK, Wang XJ

OncoTargets and Therapy 2018, 11:2075-2082

Published Date: 11 April 2018

Review

Role of the NFκB-signaling pathway in cancer

Xia LZ, Tan SM, Zhou YJ, Lin JG, Wang HR, Oyang LD, Tian YT, Liu L, Su M, Wang H, Cao D, Liao QJ

OncoTargets and Therapy 2018, 11:2063-2073

Published Date: 11 April 2018

Original Research

Combination of SIRT1 and Src overexpression suggests poor prognosis in luminal breast cancer

Tan J, Liu Y, Maimaiti Y, Wang C, Yan Y, Zhou J, Ruan S, Huang T

OncoTargets and Therapy 2018, 11:2051-2061

Published Date: 11 April 2018

Original Research

IL-21-secreting hUCMSCs combined with miR-200c inhibit tumor growth and metastasis via repression of Wnt/β-catenin signaling and epithelial-mesenchymal transition in epithelial ovarian cancer

Zhang Y, Wang J, Wu D, Li M, Zhao F, Ren M, Cai Y, Dou J

OncoTargets and Therapy 2018, 11:2037-2050

Published Date: 10 April 2018

Original Research

β-Catenin-driven adrenocortical carcinoma is characterized with immune exclusion

Liu S, Ding G, Zhou Z, Feng C

OncoTargets and Therapy 2018, 11:2029-2036

Published Date: 9 April 2018

Original Research

Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity

Yao C, Liu B, Qian X, Li L, Cao H, Guo Q, Zhou G

OncoTargets and Therapy 2018, 11:2017-2028

Published Date: 9 April 2018

Original Research

Butein activates p53 in hepatocellular carcinoma cells via blocking MDM2-mediated ubiquitination

Zhou Y, Wang K, Zhou N, Huang T, Zhu J, Li J

OncoTargets and Therapy 2018, 11:2007-2015

Published Date: 6 April 2018

Original Research

Role of presurgical targeted molecular therapy in renal cell carcinoma with an inferior vena cava tumor thrombus

Peng C, Gu L, Wang L, Huang Q, Wang B, Guo G, Fan Y, Gao Y, Ma X, Zhang X

OncoTargets and Therapy 2018, 11:1997-2005

Published Date: 6 April 2018

Case Series

Multiline treatment combining apatinib with toptecan for platinum-resistant recurrent ovarian cancer patients: a report of three cases

Cheng Y, Zhang J, Geng HY, Qin SK, Hua HQ

OncoTargets and Therapy 2018, 11:1989-1995

Published Date: 6 April 2018

Original Research

Positioning error and expanding margins of planning target volume with kilovoltage cone beam computed tomography for prostate cancer radiotherapy

Wang G, Wang WL, Liu YQ, Dong HM, Hu YX

OncoTargets and Therapy 2018, 11:1981-1988

Published Date: 6 April 2018

Original Research

Postmastectomy radiotherapy reduces locoregional and disease recurrence in patients with stage II–III triple-negative breast cancer treated with neoadjuvant chemotherapy and mastectomy

Chen XX, Xia F, Luo JR, Ma JL, Yang ZZ, Zhang L, Feng Y, Shao ZM, Yu XL, Guo XM

OncoTargets and Therapy 2018, 11:1973-1980

Published Date: 5 April 2018

Original Research

Knockdown of fibrous sheath interacting protein 1 expression reduces bladder urothelial carcinoma cell proliferation and induces apoptosis via inhibition of the PI3K/AKT pathway

Sun M, Chen Z, Tan S, Liu C, Zhao W

OncoTargets and Therapy 2018, 11:1961-1971

Published Date: 5 April 2018

Original Research

Fabrication of ultrasmall WS2 quantum dots-coated periodic mesoporous organosilica nanoparticles for intracellular drug delivery and synergistic chemo-photothermal therapy

Liao W, Zhang L, Zhong Y, Shen Y, Li C, An N

OncoTargets and Therapy 2018, 11:1949-1960

Published Date: 5 April 2018

Original Research

Inhibition of NIPBL enhances the chemosensitivity of non-small-cell lung cancer cells via the DNA damage response and autophagy pathway

Zheng L, Zhou H, Guo L, Xu X, Zhang S, Xu W, Mao W

OncoTargets and Therapy 2018, 11:1941-1948

Published Date: 5 April 2018

Original Research

Downregulation of miR-542-3p promotes cancer metastasis through activating TGF-β/Smad signaling in hepatocellular carcinoma

Zhang T, Liu W, Meng W, Zhao H, Yang Q, Gu SJ, Xiao CC, Jia CC, Fu BS

OncoTargets and Therapy 2018, 11:1929-1939

Published Date: 5 April 2018

Case report

PET-CT evaluation of the curative effect of crizotinib on malignant myofibroblastoma with rare mutation of ALK R401: a case report and literature review

Yang L, Wu Y, Tang H, Zhao J, Zhao D, Yang S, Wang Q

OncoTargets and Therapy 2018, 11:1921-1927

Published Date: 5 April 2018

Original Research

miR-495 inhibits proliferation, migration, and invasion and induces apoptosis via inhibiting PBX3 in melanoma cells

Chen G, Xie Y

OncoTargets and Therapy 2018, 11:1909-1920

Published Date: 5 April 2018

Review

Prognostic value of platelet-to-lymphocyte ratio in pancreatic cancer: a comprehensive meta-analysis of 17 cohort studies

Zhou Y, Cheng S, Fathy AH, Qian H, Zhao Y

OncoTargets and Therapy 2018, 11:1899-1908

Published Date: 5 April 2018

Original Research

99mTc-labeled sodium phytate and stannous chloride injection accurately detects sentinel lymph node in axillary of early stage breast cancer: a randomized, controlled study

Yang S, Bao W, Bai X, Gao C, Zhang B, Jiang Z

OncoTargets and Therapy 2018, 11:1891-1898

Published Date: 4 April 2018

Case report

Long-term survival with transarterial chemoembolization and radioembolization in a patient with cancers of unknown primary

Aktas G, Kus T, Metin T, Kervancioglu S, Elboga U

OncoTargets and Therapy 2018, 11:1885-1889

Published Date: 4 April 2018

Original Research

Antiangiogenic effects of AA-PMe on HUVECs in vitro and zebrafish in vivo

Jing Y, Wang G, Xiao Q, Zhou Y, Wei Y, Gong Z

OncoTargets and Therapy 2018, 11:1871-1884

Published Date: 4 April 2018

Original Research

Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis

Zhou L, Du Y, Kong L, Zhang X, Chen Q

OncoTargets and Therapy 2018, 11:1861-1869

Published Date: 4 April 2018

Original Research

Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

Wang G, Li L, Liu B, Han X, Wang CH, Wang JW

OncoTargets and Therapy 2018, 11:1849-1859

Published Date: 4 April 2018

Original Research

D-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer

Yu X, Lin H, Wang Y, Lv W, Zhang S, Qian Y, Deng X, Feng N, Yu H, Qian B

OncoTargets and Therapy 2018, 11:1833-1847

Published Date: 4 April 2018

Original Research

Clinicopathological characteristics and prognostic value of the cancer stem cell marker ALDH1 in ovarian cancer: a meta-analysis

Zhao W, Zang C, Zhang T, Li J, Liu R, Feng F, Lv Q, Zheng L, Tian J, Sun C

OncoTargets and Therapy 2018, 11:1821-1831

Published Date: 3 April 2018

Case report

Rare malignant insulinoma with multiple liver metastases derived from ectopic pancreas: 3-year follow-up and literature review

Liu Q, Duan JH, Zheng YM, Luo J, Cai XP, Tan HY

OncoTargets and Therapy 2018, 11:1813-1819

Published Date: 3 April 2018

Original Research

Association between WWOX and the risk of malignant tumor, especially among Asians: evidence from a meta-analysis

Yuan H, Wu Y, Zhang J, Shi G, Liu D, He Y, Lu Z, Wu P, Jiang K, Miao Y

OncoTargets and Therapy 2018, 11:1801-1811

Published Date: 3 April 2018

Review

Prognostic value of increased integrin-beta 1 expression in solid cancers: a meta-analysis

Sun Q, Zhou C, Ma R, Guo Q, Huang H, Hao J, Liu H, Shi R, Liu B

OncoTargets and Therapy 2018, 11:1787-1799

Published Date: 29 March 2018

Original Research

Synergistic antitumor effects of tanshinone IIA and sorafenib or its derivative SC-1 in hepatocellular carcinoma cells

Chiu CM, Huang SY, Chang SF, Liao KF, Chiu SC

OncoTargets and Therapy 2018, 11:1777-1785

Published Date: 29 March 2018

Original Research

Metformin inhibits proliferation and cytotoxicity and induces apoptosis via AMPK pathway in CD19-chimeric antigen receptor-modified T cells

Mu Q, Jiang M, Zhang Y, Wu F, Li H, Zhang W, Wang F, Liu J, Li L, Wang D, Wang W, Li S, Song H, Tang D

OncoTargets and Therapy 2018, 11:1767-1776

Published Date: 3 April 2018

Original Research

miR-206 regulates 5-FU resistance by targeting Bcl-2 in colon cancer cells

Meng X, Fu R

OncoTargets and Therapy 2018, 11:1757-1765

Published Date: 29 March 2018

Original Research

Antibody-sandwich ELISA analysis of a novel blood biomarker of CST4 in gastrointestinal cancers

Dou YL, Lv YL, Zhou XJ, He LF, Liu LH, Li PF, Sun YL, Wang MH, Gao MJ, Wang C

OncoTargets and Therapy 2018, 11:1743-1756

Published Date: 28 March 2018

Original Research

MiR-152 functioning as a tumor suppressor that interacts with DNMT1 in nasopharyngeal carcinoma

Lu Z, Du M, Qian L, Zhang N, Gu J, Ding K, Wu J, Zhu H, He X, Yin L

OncoTargets and Therapy 2018, 11:1733-1741

Published Date: 27 March 2018

Original Research

miR-1269 promotes cell survival and proliferation by targeting tp53 and caspase-9 in lung cancer

Bao M, Song YJ, Xia JJ, Li PL, Liu Q, Wan ZR

OncoTargets and Therapy 2018, 11:1721-1732

Published Date: 26 March 2018

Original Research

KIF18B promotes tumor progression through activating the Wnt/β-catenin pathway in cervical cancer

Wu Y, Wang A, Zhu B, Huang J, Lu E, Xu H, Xia W, Dong G, Jiang F, Xu L

OncoTargets and Therapy 2018, 11:1707-1720

Published Date: 28 March 2018

Original Research

Upregulated VEGFA and DLL4 act as potential prognostic genes for clear cell renal cell carcinoma

Wang X, Zhang J, Wang Y, Tu M, Wang Y, Shi G

OncoTargets and Therapy 2018, 11:1697-1706

Published Date: 26 March 2018

Original Research

Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer

Yuan W, Xie S, Wang M, Pan S, Huang X, Xiong M, Xiao R, Xiong J, Zhang Q, Shao L

OncoTargets and Therapy 2018, 11:1683-1695

Published Date: 23 March 2018

Original Research

MiR-216b suppresses colorectal cancer proliferation, migration, and invasion by targeting SRPK1

Yao YF, Li QR, Wang H

OncoTargets and Therapy 2018, 11:1671-1681

Published Date: 23 March 2018

Original Research

The incidence of postoperative radiotherapy-induced acute dermatitis in breast cancer and its influencing factors for Chinese women

Ding J, Guo Y, Li Q, Chen J, Hu P, Liu Q, Cao Y, Wu J

OncoTargets and Therapy 2018, 11:1665-1670

Published Date: 23 March 2018

Original Research

Biomarker expression in rectal cancer tissue before and after neoadjuvant therapy

Boogerd LS, van der Valk MJM, Boonstra MC, Prevoo HA, Hilling DE, van de Velde CJ, Sier CF, Fariña Sarasqueta A, Vahrmeijer AL

OncoTargets and Therapy 2018, 11:1655-1664

Published Date: 23 March 2018

Original Research

miR-342-3p suppresses hepatocellular carcinoma proliferation through inhibition of IGF-1R-mediated Warburg effect

Liu W, Kang L, Han J, Wang Y, Shen C, Yan Z, Tai Y, Zhao C

OncoTargets and Therapy 2018, 11:1643-1653

Published Date: 23 March 2018

Original Research

Effects of isoliquiritigenin on ovarian cancer cells

Li N, Yang L, Deng XN, Sun YN

OncoTargets and Therapy 2018, 11:1633-1642

Published Date: 22 March 2018

Original Research

Open adrenalectomy versus laparoscopic adrenalectomy for adrenocortical carcinoma: a retrospective comparative study on short-term oncologic prognosis

Zheng G, Li H, Deng J, Zhang X, Wu X

OncoTargets and Therapy 2018, 11:1625-1632

Published Date: 21 March 2018

Original Research

Tooth loss and risk of colorectal cancer: a dose–response meta-analysis of prospective cohort studies

Ma P, Dai S, Jin C, Yao Y, Zou C

OncoTargets and Therapy 2018, 11:1617-1623

Published Date: 21 March 2018

Original Research

Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells

Chen YC, Chen IS, Huang GJ, Kang CH, Wang KC, Tsao MJ, Pan HW

OncoTargets and Therapy 2018, 11:1601-1616

Published Date: 21 March 2018

Case report

Lung squamous cell carcinoma associated with hypoparathyroidism with sensorineural deafness and renal dysplasia syndrome: a case report

Kojima M, Nagano T, Nakata K, Hara S, Katsurada N, Yamamoto M, Tachihara M, Kamiryo H, Kobayashi K, Usui T, Nishimura Y

OncoTargets and Therapy 2018, 11:1595-1599

Published Date: 20 March 2018

Original Research

Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis

Sun L, Yang S, Chi G, Jin X

OncoTargets and Therapy 2018, 11:1583-1593

Published Date: 20 March 2018

Original Research

High expression of COL10A1 is associated with poor prognosis in colorectal cancer

Huang H, Li T, Ye G, Zhao L, Zhang Z, Mo D, Wang Y, Zhang C, Deng H, Li G, Liu H

OncoTargets and Therapy 2018, 11:1571-1581

Published Date: 20 March 2018

Original Research

Overexpression of HHLA2, a member of the B7 family, is associated with worse survival in human colorectal carcinoma

Zhu Z, Dong W

OncoTargets and Therapy 2018, 11:1563-1570

Published Date: 20 March 2018

Review

Forecast of actin-binding proteins as the oncotarget in osteosarcoma – a review of mechanism, diagnosis and therapy

Fu Y, Yu W, Cai H, Lu A

OncoTargets and Therapy 2018, 11:1553-1561

Published Date: 20 March 2018

Original Research

Novel long noncoding RNA GACAT3 promotes colorectal cancer cell proliferation, invasion, and migration through miR-149

Zhou W, Wang L, Miao Y, Xing R

OncoTargets and Therapy 2018, 11:1543-1552

Published Date: 19 March 2018

Review

Functional miRNAs in breast cancer drug resistance

Hu WZ, Tan CL, He YJ, Zhang GQ, Xu Y, Tang JH

OncoTargets and Therapy 2018, 11:1529-1541

Published Date: 19 March 2018

Case report

Primary mucinous carcinoma of thyroid gland with prominent signet-ring-cell differentiation: a case report and review of the literature

Wang J, Guli QR, Ming XC, Zhou HT, Cui YJ, Jiang YF, Zhang D, Liu Y

OncoTargets and Therapy 2018, 11:1521-1528

Published Date: 16 March 2018

Original Research

STK39 blockage by RNA interference inhibits the proliferation and induces the apoptosis of renal cell carcinoma

Zhao Q, Zhu YJ, Liu L, Wang H, Jiang S, Hu X, Guo J

OncoTargets and Therapy 2018, 11:1511-1519

Published Date: 16 March 2018

Original Research

miR-622 suppresses tumor formation by directly targeting VEGFA in papillary thyroid carcinoma

Wang R, Ma Q, Ji L, Yao Y, Ma M, Wen Q

OncoTargets and Therapy 2018, 11:1501-1509

Published Date: 16 March 2018

Original Research

Upregulated long non-coding RNAs demonstrate promising efficacy for breast cancer detection: a meta-analysis

Yu G, Zhang W, Zhu L, Xia L

OncoTargets and Therapy 2018, 11:1491-1499

Published Date: 16 March 2018

Original Research

Midazolam activates caspase, MAPKs and endoplasmic reticulum stress pathways, and inhibits cell cycle and Akt pathway, to induce apoptosis in TM3 mouse Leydig progenitor cells

Kang FC, Wang SC, Chang MM, Pan BS, Wong KL, Cheng KS, So EC, Huang BM

OncoTargets and Therapy 2018, 11:1475-1490

Published Date: 15 March 2018

Original Research

Identification of differentially expressed genes and signaling pathways in ovarian cancer by integrated bioinformatics analysis

Yang X, Zhu S, Li L, Zhang L, Xian S, Wang Y, Cheng Y

OncoTargets and Therapy 2018, 11:1457-1474

Published Date: 15 March 2018

Original Research

Modulation of human melanoma cell proliferation and apoptosis by hydatid cyst fluid of Echinococcus granulosus

Gao X, Zhang G, Huang L

OncoTargets and Therapy 2018, 11:1447-1456

Published Date: 15 March 2018

Original Research

Measurement of serum PODXL concentration for detection of pancreatic cancer

Taniuchi K, Tsuboi M, Sakaguchi M, Saibara T

OncoTargets and Therapy 2018, 11:1433-1445

Published Date: 15 March 2018

Original Research

Peripheral inflammation/immune indicators of chemosensitivity and prognosis in breast cancer patients treated with neoadjuvant chemotherapy

Qian Y, Tao J, Li X, Chen H, Lu Q, Yang J, Pan H, Wang C, Zhou W, Liu X

OncoTargets and Therapy 2018, 11:1423-1432

Published Date: 15 March 2018

Original Research

Upregulation of FOXP1 is a new independent unfavorable prognosticator and a specific predictor of lymphatic dissemination in cutaneous melanoma patients

Donizy P, Pagacz K, Marczuk J, Fendler W, Maciejczyk A, Halon A, Matkowski R

OncoTargets and Therapy 2018, 11:1413-1422

Published Date: 14 March 2018

Original Research

Long non-coding RNA FENDRR inhibits cell proliferation and is associated with good prognosis in breast cancer

Li Y, Zhang W, Liu P, Xu Y, Tang L, Chen W, Guan X

OncoTargets and Therapy 2018, 11:1403-1412

Published Date: 14 March 2018

Original Research

Fast hemostasis: a win-win strategy for ultrasound and microwave ablation

Guo J, Tian G, Zhao Q, Jiang T

OncoTargets and Therapy 2018, 11:1395-1402

Published Date: 13 March 2018

Original Research

Rhein inhibits malignant phenotypes of human renal cell carcinoma by impacting on MAPK/NF-κB signaling pathways

Ma YL, Chen F, Shi J

OncoTargets and Therapy 2018, 11:1385-1394

Published Date: 14 March 2018

Original Research

Reliability of using circulating tumor cells for detecting epidermal growth factor receptor mutation status in advanced non-small-cell lung cancer patients: a meta-analysis and systematic review

Hu F, Mao XW, Zhang YJ, Zheng XX, Gu P, Wang HM, Zhang XY

OncoTargets and Therapy 2018, 11:1373-1384

Published Date: 14 March 2018

Original Research

Evaluation of biologically active substances promoting the development of or protecting against endometrial cancer

Cymbaluk-Płoska A, Chudecka-Głaz A, Jagodzińska A, Pius-Sadowska E, Sompolska-Rzechuła A, Machaliński B, Menkiszak J

OncoTargets and Therapy 2018, 11:1363-1372

Published Date: 13 March 2018

Original Research

Clinicopathological features and prognosis in elderly gastric cancer patients: a retrospective cohort study

Xu G, Feng F, Liu S, Wang F, Zheng G, Wang Q, Cai L, Guo M, Lian X, Zhang H

OncoTargets and Therapy 2018, 11:1353-1362

Published Date: 12 March 2018

Original Research

IL13Rα2 siRNA inhibited cell proliferation, induced cell apoptosis, and suppressed cell invasion in papillary thyroid carcinoma cells

Gu MJ

OncoTargets and Therapy 2018, 11:1345-1352

Published Date: 9 March 2018

Original Research

SPP1 promotes ovarian cancer progression via Integrin β1/FAK/Akt signaling pathway

Zeng B, Zhou M, Wu H, Xiong Z

OncoTargets and Therapy 2018, 11:1333-1343

Published Date: 12 March 2018

Original Research

CREB promotes laryngeal cancer cell migration via MYCT1/NAT10 axis

Zhang ZX, Zhang WN, Sun YY, Li YH, Xu ZM, Fu WN

OncoTargets and Therapy 2018, 11:1323-1331

Published Date: 8 March 2018

Original Research

Clinicopathological characteristics and prognosis of adult ovarian granulosa cell tumor: a single-institution experience in China

Wang D, Xiang Y, Wu M, Shen K, Yang J, Huang H, Ren T

OncoTargets and Therapy 2018, 11:1315-1322

Published Date: 7 March 2018

Original Research

Prognostic significance of preoperative IKBKE expression in esophageal squamous cell carcinoma

Yang WJ, Qu Y, Tan BX, Jia YB, Wang NN, Hu P, Wang JB

OncoTargets and Therapy 2018, 11:1305-1314

Published Date: 7 March 2018

Original Research

The clinicopathological and prognostic value of HSP27 in hepatocellular carcinoma: a systematic review and meta-analysis

Liang CJ, Xu YC, Ge H, Li GM, Wu JX

OncoTargets and Therapy 2018, 11:1293-1303

Published Date: 7 March 2018

Original Research

Overexpression of c-kit(CD117), relevant with microvessel density, is an independent survival prognostic factor for patients with HBV-related hepatocellular carcinoma

Yan W, Zhu Z, Pan F, Huang A, Dai G

OncoTargets and Therapy 2018, 11:1285-1292

Published Date: 7 March 2018

Original Research

MicroRNA 302b-3p/302c-3p/302d-3p inhibits epithelial–mesenchymal transition and promotes apoptosis in human endometrial carcinoma cells

Li Y, Huo J, Pan X, Wang C, Ma X

OncoTargets and Therapy 2018, 11:1275-1284

Published Date: 6 March 2018

Original Research

Vascular endothelial growth factor suppresses dendritic cells function of human prostate cancer

Bai WK, Zhang W, Hu B

OncoTargets and Therapy 2018, 11:1267-1274

Published Date: 6 March 2018

Original Research

Decreased expression of LKB1 predicts poor prognosis in pancreatic neuroendocrine tumor patients undergoing curative resection

Li D, Zhou Y, Liu Y, Lin Y, Yu M, Lu X, Huang B, Sun Z, Jian Z, Hou B

OncoTargets and Therapy 2018, 11:1259-1265

Published Date: 6 March 2018

Original Research

Icotinib hydrochloride enhances chemo- and radiosensitivity by inhibiting EGFR signaling and attenuating RAD51 expression and function in Hela S3 cells

Wang X, Gu Y, Liu H, Shi L, Sun X

OncoTargets and Therapy 2018, 11:1245-1258

Published Date: 5 March 2018

Review

Clinical value of Xenopus kinesin-like protein 2 as a prognostic marker in patients with digestive system cancers: a systematic review and meta-analysis

Wang G, Wang Q, Li Z, Liu C, He X

OncoTargets and Therapy 2018, 11:1229-1243

Published Date: 5 March 2018

Original Research

A national, multicenter, non-interventional, observational study on treatment patterns in patients with metastatic renal cell carcinoma in Turkey – NOTES study

Yalcin Ş, Yildiz R, Dane F, Karaoğlu A, Öksüzoğlu B, Özyilkan Ö, Sevinç A, Özdemir F, Turna H, Uslu R, Ulay E

OncoTargets and Therapy 2018, 11:1223-1228

Published Date: 5 March 2018

Original Research

Leukemia-related protein 16 (LRP16) promotes tumor growth and metastasis in pancreatic cancer

Mo Z, Hu MG, Yu F, Shao LJ, Fan KX, Jiao SC

OncoTargets and Therapy 2018, 11:1215-1222

Published Date: 5 March 2018

Original Research

Clinicopathological significance and prognostic role of p-STAT3 in patients with hepatocellular carcinoma

Liang CJ, Xu Y, Ge H, Li G, Wu J

OncoTargets and Therapy 2018, 11:1203-1214

Published Date: 5 March 2018

Original Research

Impact of diabetes mellitus on the risk and survival of nasopharyngeal carcinoma: a meta-analysis

Guo G, Fu M, Wei S, Chen R

OncoTargets and Therapy 2018, 11:1193-1201

Published Date: 2 March 2018

Original Research

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma

Wang R, Deng D, Shao N, Xu Y, Xue L, Peng Y, Liu Y, Zhi F

OncoTargets and Therapy 2018, 11:1183-1192

Published Date: 2 March 2018

Original Research

Hepatitis C virus core impacts expression of miR122 and miR204 involved in carcinogenic progression via regulation of TGFBRAP1 and HOTTIP expression

Wang X, Peng J, Wang J, Li M, Wu D, Wu S, Liao J, Dou J

OncoTargets and Therapy 2018, 11:1173-1182

Published Date: 2 March 2018

Original Research

SIRT1 overexpression protects non-small cell lung cancer cells against osteopontin-induced epithelial-mesenchymal transition by suppressing NF-κB signaling

Li X, Jiang Z, Li XM, Zhang X

OncoTargets and Therapy 2018, 11:1157-1171

Published Date: 2 March 2018

Original Research

Cisplatin concurrent chemoradiotherapy vs adjuvant radiation in stage IB/IIA cervical cancer with intermediate risk factors, treated with radical surgery: a retrospective study

Sun H, Tang Q, Chen J, Lv X, Tu Y, Yan D

OncoTargets and Therapy 2018, 11:1149-1155

Published Date: 6 March 2018

Original Research

Effects of propofol-based total intravenous anesthesia on gastric cancer: a retrospective study

Zheng XY, Wang Y, Dong LL, Zhao S, Wang LP, Chen H, Xu Y, Wang GN

OncoTargets and Therapy 2018, 11:1141-1148

Published Date: 1 March 2018

Review

rs11614913 polymorphism in miRNA-196a2 and cancer risk: an updated meta-analysis

Liu Y, He A, Liu B, Zhong Y, Liao X, Yang J, Chen J, Wu J, Mei H

OncoTargets and Therapy 2018, 11:1121-1139

Published Date: 1 March 2018

Case report

Response to crizotinib in a non-small-cell lung cancer patient harboring an EML4-ALK fusion with an atypical LTBP1 insertion

Aguado C, Gil MDLL, Yeste Z, Giménez-Capitán A, Teixidó C, Karachaliou N, Viteri S, Rosell R, Molina-Vila MA

OncoTargets and Therapy 2018, 11:1117-1120

Published Date: 1 March 2018

Original Research

The efficacy and safety of alectinib in the treatment of ALK+ NSCLC: a systematic review and meta-analysis

Fan JS, Xia ZF, Zhang XL, Chen YQ, Qian RL, Liu SH, You DM, Zhang J, Luo P

OncoTargets and Therapy 2018, 11:1105-1115

Published Date: 1 March 2018

Original Research

TSPAN12 is overexpressed in NSCLC via p53 inhibition and promotes NSCLC cell growth in vitro and in vivo

Hu Z, Hou D, Wang X, You Z, Cao X

OncoTargets and Therapy 2018, 11:1095-1103

Published Date: 1 March 2018

Original Research

Comparison between multi-slice spiral CT and magnetic resonance imaging in the diagnosis of peritoneal metastasis in primary ovarian carcinoma

Guo HL, He L, Zhu YC, Wu K, Yuan F

OncoTargets and Therapy 2018, 11:1087-1094

Published Date: 28 February 2018

Original Research

Association of doublecortin-like kinase 1 with tumor aggressiveness and poor biochemical recurrence-free survival in prostate cancer

Jiang DG, Xiao CT, Xian TZ, Wang LT, Mao YH, Zhang JF, Pang J

OncoTargets and Therapy 2018, 11:1077-1086

Published Date: 28 February 2018

Original Research

Forkhead box K2 inhibits the proliferation, migration, and invasion of human glioma cells and predicts a favorable prognosis

Wang B, Zhang XB, Wang W, Zhu ZZ, Tang F, Wang D, Liu X, Zhuang H, Yan XL

OncoTargets and Therapy 2018, 11:1067-1075

Published Date: 27 February 2018

Original Research

Genetic association between HER2 and ESR2 polymorphisms and ovarian cancer: a meta-analysis

Tang L, Li J, Bao M, Xiang J, Chen Y, Wang Y

OncoTargets and Therapy 2018, 11:1055-1066

Published Date: 1 March 2018

Original Research

CXCR3 is a prognostic marker and a potential target for patients with solid tumors: a meta-analysis

Zhang Y, Xu L, Peng M

OncoTargets and Therapy 2018, 11:1045-1054

Published Date: 27 February 2018

Original Research

Clinicopathologic characteristics and prognosis of proximal and distal gastric cancer

Yu X, Hu F, Li C, Yao Q, Zhang H, Xue Y

OncoTargets and Therapy 2018, 11:1037-1044

Published Date: 27 February 2018

Original Research

Reversine, a substituted purine, exerts an inhibitive effect on human renal carcinoma cells via induction of cell apoptosis and polyploidy

Cheng L, Wang H, Guo KC, Wang ZC, Zhang ZY, Shen C, Chen L, Lin J

OncoTargets and Therapy 2018, 11:1025-1035

Published Date: 26 February 2018

Original Research

Prognostic value of circulating tumor cells detected with the CellSearch System in patients with gastric cancer: evidence from a meta-analysis

Yang C, Zou K, Yuan Z, Guo T, Xiong B

OncoTargets and Therapy 2018, 11:1013-1023

Published Date: 26 February 2018

Original Research

How many ELNs are optimal for breast cancer patients with more than three PLNs who underwent MRM? A large population-based study

Wang X, Ji C, Chi H, Wang H

OncoTargets and Therapy 2018, 11:1005-1011

Published Date: 26 February 2018

Review

Prognostic significance of Epstein–Barr virus DNA in NK/T-cell lymphoma: a meta-analysis

Fei Q, Tian X, Wu J, Zhu H, Wang Y, Peng F, Zhang W, Yin L, He X

OncoTargets and Therapy 2018, 11:997-1004

Published Date: 26 February 2018

Original Research

Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway

Yang C, Hou A, Yu C, Dai L, Wang W, Zhang K, Shao H, Ma J, Xu W

OncoTargets and Therapy 2018, 11:983-996

Published Date: 26 February 2018

Original Research

Role of palliative resection of the primary pancreatic neuroendocrine tumor in patients with unresectable metastatic liver disease: a systematic review and meta-analysis

Zhou B, Zhan C, Ding Y, Yan S, Zheng S

OncoTargets and Therapy 2018, 11:975-982

Published Date: 23 February 2018

Original Research

Prognostic significance of mucinous component in gastric adenocarcinoma after radical D2 gastrectomy

Cai L, Li Y, Yang X, Lian X, Guo M, Xiao S, Wang W, Zhang H

OncoTargets and Therapy 2018, 11:967-973

Published Date: 23 February 2018

Review

Prognostic utility of baseline neutrophil-to-lymphocyte ratio in patients receiving immune checkpoint inhibitors: a review and meta-analysis

Sacdalan DB, Lucero JA, Sacdalan DL

OncoTargets and Therapy 2018, 11:955-965

Published Date: 23 February 2018

Original Research

Role of ubenimex as an anticancer drug and its synergistic effect with Akt inhibitor in human A375 and A2058 cells

Wang X, Liu Y, Wu R, Guo F, Zhang L, Cui M, Wu X, Zhang Y, Liu W

OncoTargets and Therapy 2018, 11:943-953

Published Date: 22 February 2018

Original Research

Characterization of luteinizing hormone-releasing hormone receptor type I (LH-RH-I) as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines

Sipos E, Dobos N, Rozsa D, Fodor K, Olah G, Szabo Z, Szekvolgyi L, Schally AV, Halmos G

OncoTargets and Therapy 2018, 11:933-941

Published Date: 22 February 2018

Original Research

The investigation for potential modifier genes in patients with neurofibromatosis type 1 based on next-generation sequencing

Yang F, Xu S, Liu RW, Shi T, Li XF, Li XB, Chen G, Liu HY, Zhou QH, Chen J

OncoTargets and Therapy 2018, 11:919-932

Published Date: 21 February 2018

Original Research

Low levels of tumor suppressor candidate 3 predict poor prognosis of patients with hepatocellular carcinoma

Sheng XR, Xing SG, Wang RD, Chen K, Jia WD

OncoTargets and Therapy 2018, 11:909-917

Published Date: 21 February 2018

Original Research

Postoperative hepatic arterial infusion chemotherapy improved survival of pancreatic cancer after radical pancreatectomy: a retrospective study

Wang Y, Xu Y, Zheng Y, Bao Y, Wang P

OncoTargets and Therapy 2018, 11:903-907

Published Date: 21 February 2018

Original Research

CDCA5 regulates proliferation in hepatocellular carcinoma and has potential as a negative prognostic marker

Shen Z, Yu X, Zheng Y, Lai X, Li J, Hong Y, Zhang H, Chen C, Su Z, Guo R

OncoTargets and Therapy 2018, 11:891-901

Published Date: 20 February 2018

Case Series

Successful treatment of metastatic colorectal cancer with apatinib: report of two cases and literature review

Bi MH, Yang JR, Wang YP, Zhang HR, Gao ZY, Zhou HR, Shi MH

OncoTargets and Therapy 2018, 11:883-890

Published Date: 19 February 2018

Original Research

Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy

Chen X, Tong H, Chen Y, Chen C, Ye J, Mo Q, Zhao G, Hong G, Zheng C, Lu Z

OncoTargets and Therapy 2018, 11:867-881

Published Date: 19 February 2018

Original Research

Effects of four single nucleotide polymorphisms of EZH2 on cancer risk: a systematic review and meta-analysis

Ling Z, You Z, Hu L, Zhang L, Wang Y, Zhang M, Zhang G, Chen S, Xu B, Chen M

OncoTargets and Therapy 2018, 11:851-865

Published Date: 16 February 2018

Original Research

Interleukin-33 enhanced the migration and invasiveness of human lung cancer cells

Yang Z, Gao X, Wang J, Xu L, Zheng Y, Xu Y

OncoTargets and Therapy 2018, 11:843-849

Published Date: 16 February 2018

Review

Developments in the management of advanced soft-tissue sarcoma – olaratumab in context

Moroncini G, Maccaroni E, Fiordoliva I, Pellei C, Gabrielli A, Berardi R

OncoTargets and Therapy 2018, 11:833-842

Published Date: 16 February 2018

Original Research

MiR-1180-5p regulates apoptosis of Wilms’ tumor by targeting p73

Jiang X, Li H

OncoTargets and Therapy 2018, 11:823-831

Published Date: 16 February 2018

Original Research

Knockdown of KLK11 reverses oxaliplatin resistance by inhibiting proliferation and activating apoptosis via suppressing the PI3K/AKT signal pathway in colorectal cancer cell

Zhang Y, Xu Z, Sun Y, Chi P, Lu X

OncoTargets and Therapy 2018, 11:809-821

Published Date: 16 February 2018

Original Research

Clinical significance of quantitative HER2 gene amplification as related to its predictive value in breast cancer patients in neoadjuvant setting

Wu Z, Xu S, Zhou L, Yin W, Lin Y, Du Y, Wang Y, Jiang Y, Yin K, Zhang J, Lu J

OncoTargets and Therapy 2018, 11:801-808

Published Date: 15 February 2018

Original Research

The association between HOTAIR polymorphisms and cancer susceptibility: an updated systemic review and meta-analysis

Min L, Mu X, Tong A, Qian Y, Ling C, Yi T, Zhao X

OncoTargets and Therapy 2018, 11:791-800

Published Date: 14 February 2018

Original Research

ISL1 is upregulated in breast cancer and promotes cell proliferation, invasion, and angiogenesis

Li L, Sun F, Chen X, Zhang M

OncoTargets and Therapy 2018, 11:781-789

Published Date: 14 February 2018

Original Research

Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial–mesenchymal transition via regulating the PI3K/AKT/mTOR pathway

Huang Y, Wu S, Zhang Y, Wang L, Guo Y

OncoTargets and Therapy 2018, 11:769-779

Published Date: 12 February 2018

Original Research

Raptor mediates the antiproliferation of cardamonin by mTORC1 inhibition in SKOV3 cells

Shi D, Zhu Y, Niu P, Zhou J, Chen H

OncoTargets and Therapy 2018, 11:757-767

Published Date: 9 February 2018

Case report

Molecular features of giant-cell carcinoma of the lung: a case report and literature review

Li X, Zhang ZH, Liu JH, Wang D, Wei S, Chen J

OncoTargets and Therapy 2018, 11:751-756

Published Date: 9 February 2018

Original Research

Expression of Nemo-like kinase in cervical squamous cell carcinoma: a clinicopathological study

Yang W, Gu L, Yang C, Liu T

OncoTargets and Therapy 2018, 11:743-749

Published Date: 8 February 2018

Original Research

Prognostic significance of epidermal growth factor receptor expression in glioma patients

Li JH, Liang RF, Song C, Xiang YF, Liu YH

OncoTargets and Therapy 2018, 11:731-742

Published Date: 7 February 2018

Original Research

Efficacy and safety of COX-2 inhibitors for advanced non-small-cell lung cancer with chemotherapy: a meta-analysis

Dai P, Li J, Ma XP, Huang J, Meng JJ, Gong P

OncoTargets and Therapy 2018, 11:721-730

Published Date: 5 February 2018

Original Research

Use of phosphodiesterase type 5 inhibitors and risk of melanoma: a meta-analysis of observational studies

Han X, Han Y, Zheng Y, Sun Q, Ma T, Dai L, Zhang J, Xu L

OncoTargets and Therapy 2018, 11:711-720

Published Date: 5 February 2018

Original Research

Association between IL-17A G197A polymorphism and gastric cancer risk: an updated meta-analysis based on 6,624 cases and 7,631 controls

Hu L, Kong F, Pan Y

OncoTargets and Therapy 2018, 11:703-710

Published Date: 5 February 2018

Original Research

Overexpression of Zwint predicts poor prognosis and promotes the proliferation of hepatocellular carcinoma by regulating cell-cycle-related proteins

Ying H, Xu Z, Chen M, Zhou S, Liang X, Cai X

OncoTargets and Therapy 2018, 11:689-702

Published Date: 2 February 2018

Corrigendum

PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells [Corrigendum]

Guo L, Huang S, Wang X

OncoTargets and Therapy 2018, 11:687-688

Published Date: 2 February 2018

Original Research

Effects of core needle biopsy and subsequent neoadjuvant chemotherapy on molecular alterations and outcome in breast cancer

Xie L, Li X, Wang Q, Zhou J, Shen J, Luo L, Lu Y, Wang L

OncoTargets and Therapy 2018, 11:677-685

Published Date: 1 February 2018

Original Research

Associations between ABCG2 gene polymorphisms and gefitinib toxicity in non-small cell lung cancer: a meta-analysis

Tang LN, Zhang CL, He HR, Pan ZY, Fan D, He YL, You HS, Li YJ

OncoTargets and Therapy 2018, 11:665-675

Published Date: 1 February 2018

Original Research

Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance

Li J, Ye D, Wang L, Peng Y, Li Q, Deng H, Zhou C

OncoTargets and Therapy 2018, 11:651-663

Published Date: 1 February 2018

Original Research

LincRNA-ROR promotes metastasis and invasion of esophageal squamous cell carcinoma by regulating miR-145/FSCN1

Shang M, Wang X, Zhang Y, Gao Z, Wang T, Liu R

OncoTargets and Therapy 2018, 11:639-649

Published Date: 31 January 2018

Original Research

The lncRNA PCAT1 is correlated with poor prognosis and promotes cell proliferation, invasion, migration and EMT in osteosarcoma

Zhang X, Zhang Y, Mao Y, Ma X

OncoTargets and Therapy 2018, 11:629-638

Published Date: 31 January 2018

Original Research

The application of a three-dimensional visualized seed planning and navigation system in 125I seed implantation for pancreatic cancer

Hu YY, Qi EP, Liu FY, Lu YH, Tan SL, Sun Y, Han ZY, Liang P, Yu XL

OncoTargets and Therapy 2018, 11:619-627

Published Date: 31 January 2018

Original Research

Identification of genomic expression differences between right-sided and left-sided colon cancer based on bioinformatics analysis

Peng Q, Lin K, Chang T, Zou L, Xing P, Shen Y, Zhu Y

OncoTargets and Therapy 2018, 11:609-618

Published Date: 31 January 2018

Original Research

ALDH1A2 suppresses epithelial ovarian cancer cell proliferation and migration by downregulating STAT3

Wang Y, Shao F, Chen L

OncoTargets and Therapy 2018, 11:599-608

Published Date: 31 January 2018

Original Research

Application of serum microRNA-9-5p, 21-5p, and 223-3p combined with tumor markers in the diagnosis of non-small-cell lung cancer in Yunnan in southwestern China

Yang YL, Chen K, Zhou YC, Hu ZX, Chen S, Huang YC

OncoTargets and Therapy 2018, 11:587-597

Published Date: 30 January 2018

Original Research

miR-106b-5p promotes stem cell-like properties of hepatocellular carcinoma cells by targeting PTEN via PI3K/Akt pathway

Shi DM, Bian XY, Qin CD, Wu WZ

OncoTargets and Therapy 2018, 11:571-585

Published Date: 26 January 2018

Original Research

A non-synonymous polymorphism in NBS1 is associated with progression from chronic hepatitis B virus infection to hepatocellular carcinoma in a Chinese population

Zhen YN, Xiao RX, Chen X, Yuan CJ, Sun YL, Li J

OncoTargets and Therapy 2018, 11:563-569

Published Date: 26 January 2018

Original Research

Clinical manifestations of pulmonary mucosa-associated lymphoid tissue lymphoma: single-center experience with 18 patients

Zhao S, Zhang L, Gu Z, Zhu C, Fang S, Yang N, Wang F, Guan L, Luo L, Gao C

OncoTargets and Therapy 2018, 11:555-561

Published Date: 24 January 2018

Original Research

Quantification of heart, pericardium, and left ventricular myocardium movements during the cardiac cycle for thoracic tumor radiotherapy

Tong Y, Yin Y, Lu J, Liu T, Chen J, Cheng P, Gong G

OncoTargets and Therapy 2018, 11:547-554

Published Date: 24 January 2018

Original Research

Nomogram for predicting survival in patients with pancreatic cancer

Song W, Miao DL, Chen L

OncoTargets and Therapy 2018, 11:539-545

Published Date: 24 January 2018

Review

Clinical efficacy and safety of afatinib in the treatment of non-small-cell lung cancer in Chinese patients

Wang LY, Cui JJ, Guo AX, Yin JY

OncoTargets and Therapy 2018, 11:529-538

Published Date: 24 January 2018

Original Research

The role of bevacizumab in targeted vascular endothelial growth factor therapy for epithelial ovarian cancer: an updated systematic review and meta-analysis

Ruan GY, Ye LX, Liu GF, An J, Sehouli J, Sun PM

OncoTargets and Therapy 2018, 11:521-528

Published Date: 23 January 2018

Original Research

The prognostic role of Gas6/Axl axis in solid malignancies: a meta-analysis and literature review

Zhang S, Xu XS, Yang JX, Guo JH, Chao TF, Tong YX

OncoTargets and Therapy 2018, 11:509-519

Published Date: 23 January 2018

Original Research

Prognostic role of neutrophil–lymphocyte ratio in multiple myeloma: a dose–response meta-analysis

Mu S, Ai L, Fan F, Sun C, Hu Y

OncoTargets and Therapy 2018, 11:499-507

Published Date: 23 January 2018

Original Research

ROS-dependent Bax/Bcl2 and caspase 3 pathway-mediated apoptosis induced by zineb in human keratinocyte cells

Ali D, Tripathi A, Al Ali H, Shahi Y, Mishra KK, Alarifi S, Alkahtane AA, Manohardas S

OncoTargets and Therapy 2018, 11:489-497

Published Date: 23 January 2018

Case report

Synovial sarcoma of the maxillary sinus: an extremely rare case with excellent response to chemotherapy

Saito S, Ozawa H, Ikari Y, Nakahara N, Ito F, Sekimizu M, Fukada J, Kameyama K, Ogawa K

OncoTargets and Therapy 2018, 11:483-488

Published Date: 23 January 2018

Original Research

Homeobox C10 knockdown suppresses cell proliferation and promotes cell apoptosis in osteosarcoma cells through regulating caspase 3

Xie X, Xiao Y, Huang X

OncoTargets and Therapy 2018, 11:473-482

Published Date: 22 January 2018

Review

Subsequent anti-VEGF therapy after first-line anti-EGFR therapy improved overall survival of patients with metastatic colorectal cancer

Qiu TZ, Chen WS, Li P, Sun J, Gu YH, Chen XF

OncoTargets and Therapy 2018, 11:465-471

Published Date: 22 January 2018

Case report

Apatinib-treated advanced medullary thyroid carcinoma: a case report

Chen K, Gao Y, Shi F, Cao G, Bao J

OncoTargets and Therapy 2018, 11:459-463

Published Date: 19 January 2018

Original Research

Association of clinicopathologic characteristics and outcomes with EZH2 expression in patients with breast cancer in East Azerbaijan, Iran

Boostani F, Dolatkhah R, Fakhrjou A, Farassati F, Sanaat Z

OncoTargets and Therapy 2018, 11:449-457

Published Date: 19 January 2018

Original Research

Overexpression of LBH is associated with poor prognosis in human hepatocellular carcinoma

Chen JW, Huang CQ, Chen K, Li SM, Zhang X, Cheng J, Cai MY, Xiao Y

OncoTargets and Therapy 2018, 11:441-448

Published Date: 19 January 2018

Original Research

Long noncoding RNA H19 promotes transforming growth factor-β-induced epithelial–mesenchymal transition by acting as a competing endogenous RNA of miR-370-3p in ovarian cancer cells

Li J, Huang YY, Deng XJ, Luo ML, Wang XF, Hu HY, Liu CD, Zhong M

OncoTargets and Therapy 2018, 11:427-440

Published Date: 18 January 2018

Original Research

Biosimilar filgrastim vs filgrastim: a multicenter nationwide observational bioequivalence study in patients with chemotherapy-induced neutropenia

Sevinç A, Özkan M, Özet A, Dane F, Öksüzoğlu B, Işıkdoğan A, Özdemir F, Uncu D, Gümüş M, Evrensel T, Yaren A, Kara O, Tekin SB

OncoTargets and Therapy 2018, 11:419-426

Published Date: 18 January 2018

Original Research

Neoadjuvant chemoradiotherapy followed by surgery in patients with unresectable locally advanced colon cancer: a prospective observational study

Chang H, Yu X, Xiao W, Wang QX, Zhou WH, Zeng ZF, Ding PR, Li L, Gao YH

OncoTargets and Therapy 2018, 11:409-418

Published Date: 17 January 2018

Original Research

Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway

Daya M, Loilome W, Techasen A, Thanee M, Sa-Ngiamwibool P, Titapun A, Yongvanit P, Namwat N

OncoTargets and Therapy 2018, 11:395-408

Published Date: 18 January 2018

Original Research

Prognostic role of HSF1 overexpression in solid tumors: a pooled analysis of 3,159 patients

Wan T, Shao J, Hu B, Liu G, Luo P, Zhou Y

OncoTargets and Therapy 2018, 11:383-393

Published Date: 17 January 2018

Original Research

Comparison of FOLFOX and DOF regimens as first-line treatment in East Asian patients with advanced gastric cancer

Liu M, Hu G, Wang Y, Guo J, Liu L, Han X, Wang Z

OncoTargets and Therapy 2018, 11:375-381

Published Date: 17 January 2018

Original Research

Combination of betulinic acid with diazen-1-ium-1,2-diolate nitric oxide moiety donating a novel anticancer candidate

Zhang L, Hou S, Li B, Pan J, Jiang L, Zhou G, Gu H, Zhao C, Lu H, Ma F

OncoTargets and Therapy 2018, 11:361-373

Published Date: 15 January 2018

Original Research

Prognostic role of HSPs in human gastrointestinal cancer: a systematic review and meta-analysis

Ge H, Yan Y, Guo L, Tian F, Wu D

OncoTargets and Therapy 2018, 11:351-359

Published Date: 15 January 2018

Original Research

Safety and efficacy of transarterial chemoembolization with degradable starch microspheres (DSM-TACE) in the treatment of secondary liver malignancies

Schicho A, Pereira PL, Michalik K, Beyer LP, Stroszczynski C, Wiggermann P

OncoTargets and Therapy 2018, 11:345-350

Published Date: 12 January 2018

Original Research

The clinical characteristics and prognostic analysis of Chinese advanced NSCLC patients based on circulating tumor DNA sequencing

Rao C, Nie L, Miao X, Xu Y, Li B, Zhang T

OncoTargets and Therapy 2018, 11:337-344

Published Date: 12 January 2018

Original Research

High-frequency deregulated expression of Wnt signaling pathway members in breast carcinomas

Khan Z, Arafah M, Shaik JP, Mahale A, Alanazi MS

OncoTargets and Therapy 2018, 11:323-335

Published Date: 11 January 2018

Original Research

The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway

Jia L, Tian Y, Chen Y, Zhang G

OncoTargets and Therapy 2018, 11:313-321

Published Date: 11 January 2018

Original Research

A novel tumor suppressor gene NCOA5 is correlated with progression in papillary thyroid carcinoma

Zheng Z, Wang Q, Zhang W, Zhang X, Huang D

OncoTargets and Therapy 2018, 11:307-311

Published Date: 11 January 2018

Original Research

Comparative study of clinical efficacy using three-dimensional and two-dimensional laparoscopies in the treatment of distal gastric cancer

Liu JG, Zhou HT, Qin HQ, Ru HM, Huang JH, Liang SY, Mo XW, Tang WZ

OncoTargets and Therapy 2018, 11:301-306

Published Date: 11 January 2018

Original Research

Exosome-mediated delivery of MALAT1 induces cell proliferation in breast cancer

Zhang P, Zhou H, Lu K, Lu Y, Wang Y, Feng T

OncoTargets and Therapy 2018, 11:291-299

Published Date: 9 January 2018

Original Research

Over-expression of ARHGAP18 suppressed cell proliferation, migration, invasion, and tumor growth in gastric cancer by restraining over-activation of MAPK signaling pathways

Li Y, Ji S, Fu L, Jiang T, Wu D, Meng F

OncoTargets and Therapy 2018, 11:279-290

Published Date: 9 January 2018

Original Research

Experimental study of inhibitory effects of diallyl trisulfide on the growth of human osteosarcoma Saos-2 cells by downregulating expression of glucose-regulated protein 78

Zhang Y, Xie WP, Zhang YK, Chen YQ, Wang DL, Li G, Guan DH

OncoTargets and Therapy 2018, 11:271-277

Published Date: 9 January 2018

Original Research

A support vector machine and a random forest classifier indicates a 15-miRNA set related to osteosarcoma recurrence

He Y, Ma J, Wang A, Wang W, Luo S, Liu Y, Ye X

OncoTargets and Therapy 2018, 11:253-269

Published Date: 5 January 2018

Original Research

miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells

Tsai TF, Lin JF, Chou KY, Lin YC, Chen HE, Hwang TIS

OncoTargets and Therapy 2018, 11:239-252

Published Date: 4 January 2018

Original Research

Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance

Vert A, Castro J, Ribó M, Vilanova M, Benito A

OncoTargets and Therapy 2018, 11:221-237

Published Date: 4 January 2018

Original Research

RACK1 induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression

Liu B, Wang C, Chen P, Cheng B, Cheng Y

OncoTargets and Therapy 2018, 11:211-220

Published Date: 4 January 2018

Original Research

KDM2B overexpression correlates with poor prognosis and regulates glioma cell growth

Wang Y, Zang J, Zhang D, Sun Z, Qiu B, Wang X

OncoTargets and Therapy 2018, 11:201-209

Published Date: 8 January 2018

Original Research

Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/β-catenin signaling

Hu P, Cheng B, He Y, Wei Z, Wu D, Meng Z

OncoTargets and Therapy 2018, 11:193-200

Published Date: 4 January 2018

Original Research

The effects of naloxone on human breast cancer progression: in vitro and in vivo studies on MDA.MB231 cells

Bimonte S, Barbieri A, Cascella M, Rea D, Palma G, Del Vecchio V, Forte CA, Del Prato F, Arra C, Cuomo A

OncoTargets and Therapy 2018, 11:185-191

Published Date: 3 January 2018

Editorial

Cancer stem cells, the ultimate targets in cancer therapy

Shabbir A, Esfandyari T, Farassati F

OncoTargets and Therapy 2018, 11:183-184

Published Date: 3 January 2018

Review

Spotlight on midostaurin in the treatment of FLT3-mutated acute myeloid leukemia and systemic mastocytosis: design, development, and potential place in therapy

Weisberg E, Sattler M, Manley PW, Griffin JD

OncoTargets and Therapy 2018, 11:175-182

Published Date: 29 December 2017

Original Research

Identification of key pathways and genes in TP53 mutation acute myeloid leukemia: evidence from bioinformatics analysis

Huang R, Liao X, Li Q

OncoTargets and Therapy 2018, 11:163-173

Published Date: 28 December 2017

Case report

A patient with classic biphasic pulmonary blastoma harboring CD74–ROS1 fusion responds to crizotinib

Meng Z, Chen P, Zang F, Liu Y, Xu X, Su Y, Chen J, Lin L, Zhang L, Zhang T

OncoTargets and Therapy 2018, 11:157-161

Published Date: 28 December 2017

Review

Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy

Castelli G, Pelosi E, Testa U

OncoTargets and Therapy 2018, 11:131-155

Published Date: 28 December 2017

Original Research

Assessment of the cardiac safety between cetuximab and panitumumab as single therapy in Chinese chemotherapy-refractory mCRC

Tang XM, Chen H, Li Q, Song YL, Zhang SP, Xu XS, Xu YW, Chen SL

OncoTargets and Therapy 2018, 11:123-129

Published Date: 28 December 2017

Original Research

A retrospective examination of the US Food and Drug Administration’s clinical pharmacology reviews of oncology biologics for potential use of therapeutic drug monitoring

Fleisher B, Ait-Oudhia S

OncoTargets and Therapy 2018, 11:113-121

Published Date: 27 December 2017

Original Research

The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1

Zhang X, Li P, Ding Z, Wang H, Wang J, Han L, Ding S

OncoTargets and Therapy 2018, 11:103-112

Published Date: 27 December 2017

Review

The RNASEL −1385G/A polymorphism is associated with risk of prostate cancer in Africans

Liu X, Zheng D, Lu G, Yang B

OncoTargets and Therapy 2018, 11:97-102

Published Date: 22 December 2017

Original Research

Prognosis of patients with primary malignant main stem bronchial tumors: 7,418 cases based on the SEER database

Ma K, Sun F, Yang X, Wang S, Wang L, Jin Y, Shi Y, Jiang W, Zhan C, Wang Q

OncoTargets and Therapy 2018, 11:83-95

Published Date: 22 December 2017

Original Research

Real-world usage and clinical outcomes of alectinib among post-crizotinib progression anaplastic lymphoma kinase positive non-small-cell lung cancer patients in the USA

DiBonaventura MD, Wong W, Shah-Manek B, Schulz M

OncoTargets and Therapy 2018, 11:75-82

Published Date: 22 December 2017

Original Research

miR-136 targets MIEN1 and involves the metastasis of colon cancer by suppressing epithelial-to-mesenchymal transition

Ren H, Qi Y, Yin X, Gao J

OncoTargets and Therapy 2018, 11:67-74

Published Date: 22 December 2017

Original Research

Pretreatment platelet count as a prognostic factor in patients with pancreatic cancer: a systematic review and meta-analysis

Chen S, Na N, Jian Z

OncoTargets and Therapy 2018, 11:59-65

Published Date: 21 December 2017

Review

Clinicopathological and prognostic significance of OCT4 in patients with hepatocellular carcinoma: a meta-analysis

Liang CJ, Xu YC, Ge H, Li GM, Wu JX

OncoTargets and Therapy 2018, 11:47-57

Published Date: 21 December 2017

Original Research

Upregulated LAMB3 increases proliferation and metastasis in thyroid cancer

Wang Y, Jin Y, Bhandari A, Yao Z, Yang F, Pan Y, Zheng Z, Lv S, Wang O

OncoTargets and Therapy 2018, 11:37-46

Published Date: 21 December 2017

Original Research

Four-miRNA signature as a prognostic tool for lung adenocarcinoma

Lin Y, Lv Y, Liang R, Yuan C, Zhang J, He D, Zheng X, Zhang J

OncoTargets and Therapy 2018, 11:29-36

Published Date: 21 December 2017

Original Research

Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway

Gong C, Yang Z, Zhang L, Wang Y, Gong W, Liu Y

OncoTargets and Therapy 2018, 11:17-27

Published Date: 21 December 2017

Original Research

Identification of epigenetically altered genes and potential gene targets in melanoma using bioinformatic methods

Duan HH, Jiang K, Wei DK, Zhang LJ, Cheng DL, Lv M, Xu YB, He AM

OncoTargets and Therapy 2018, 11:9-15

Published Date: 20 December 2017

Original Research

ERCC1 rs3212986 A/C polymorphism is not associated with chemotherapy treatment outcomes in gastric cancer patients: evidence from 11 publications in Chinese populations

Tang WW, Wang H, Wang YM, Wang XW

OncoTargets and Therapy 2018, 11:1-8

Published Date: 20 December 2017

Retraction

ALK-positive anaplastic large cell lymphoma with soft tissue involvement in a young woman [Retraction]

Gao K, Li H, Huang C, Li H, Fang J, Tian C

OncoTargets and Therapy 2017, 10:5945-5946

Published Date: 18 December 2017

Original Research

Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

Guo Y, Wang P, Wang P, Gao W, Li F, Yang X, Ni H, Shen W, Guo Z

OncoTargets and Therapy 2017, 10:5937-5943

Published Date: 15 December 2017

Retraction

SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma [Retraction]

Huang W, Huang H, Wang L, Hu J, Song W

OncoTargets and Therapy 2017, 10:5935-5936

Published Date: 18 December 2017

Original Research

Nuclear expression of XBP1s is correlated with breast cancer survival: a retrospective analysis based on tissue microarray

Wang M, Ruan S, Ming J, Dong F

OncoTargets and Therapy 2017, 10:5927-5934

Published Date: 13 December 2017

Original Research

Seven-microRNA panel for lung adenocarcinoma early diagnosis in patients presenting with ground-glass nodules

He Y, Yang Y, Kuang P, Ren S, Rozeboom L, Rivard CJ, Li X, Zhou C, Hirsch FR

OncoTargets and Therapy 2017, 10:5915-5926

Published Date: 13 December 2017

Original Research

High expression of CIP2A protein is associated with tumor aggressiveness in stage I–III NSCLC and correlates with poor prognosis

Cha GQ, Xu JY, Xu XY, Li B, Lu S, Nanding AB, Hu SL, Liu SL

OncoTargets and Therapy 2017, 10:5907-5914

Published Date: 12 December 2017

Original Research

miR-199a modulates cisplatin resistance in ovarian cancer by targeting Hif1α

Feng X, Liu N, Deng S, Zhang DD, Wang KX, Lu MS

OncoTargets and Therapy 2017, 10:5899-5906

Published Date: 12 December 2017

Original Research

Integrative analysis of lncRNAs and miRNAs with coding RNAs associated with ceRNA crosstalk network in triple negative breast cancer

Yuan NJ, Zhang G, Bie FJ, Ma M, Ma Y, Jiang X, Wang Y, Hao X

OncoTargets and Therapy 2017, 10:5883-5897

Published Date: 12 December 2017

Original Research

Targeting of GIT1 by miR-149* in breast cancer suppresses cell proliferation and metastasis in vitro and tumor growth in vivo

Dong Y, Chang C, Liu J, Qiang J

OncoTargets and Therapy 2017, 10:5873-5882

Published Date: 11 December 2017

Original Research

Overexpression of UHRF2 in intrahepatic cholangiocarcinoma and its clinical significance

Peng R, Huang X, Zhang C, Yang X, Xu Y, Bai D

OncoTargets and Therapy 2017, 10:5863-5872

Published Date: 11 December 2017

Original Research

Deletion and downregulation of MTAP contribute to the motility of esophageal squamous carcinoma cells

Cheng X, Liu Z, Shang L, Cai H, Zhang Y, Cai Y, Xu X, Hao J, Wang M

OncoTargets and Therapy 2017, 10:5855-5862

Published Date: 11 December 2017

Original Research

Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-κB pathway

Cheng N, Guo Y

OncoTargets and Therapy 2017, 10:5843-5853

Published Date: 11 December 2017

Original Research

Intensity-modulated radiotherapy plus nimotuzumab with or without concurrent chemotherapy for patients with locally advanced nasopharyngeal carcinoma

Huang JF, Zou QZ, Qian DQ, Zhou LY, Yang B, Chu JJ, Pang QF, Wang KW, Zhang FZ

OncoTargets and Therapy 2017, 10:5835-5841

Published Date: 8 December 2017

Original Research

The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer

Wu Y, Gong L, Xu J, Mou Y, Xu X, Qian Z

OncoTargets and Therapy 2017, 10:5827-5834

Published Date: 8 December 2017

Original Research

Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway

Cui LZ, Zhao YW, Pan Y, Zheng X, Shao D, Jia Y, He K, Li K, Chen L

OncoTargets and Therapy 2017, 10:5817-5826

Published Date: 8 December 2017

Original Research

Prognostic role of CD82/KAI1 in multiple human malignant neoplasms: a meta-analysis of 31 studies

Zhu J, Miao C, Liu S, Tian Y, Zhang C, Liang C, Xu A, Cao Q, Wang Z

OncoTargets and Therapy 2017, 10:5805-5816

Published Date: 6 December 2017

Original Research

The combination astemizole–gefitinib as a potential therapy for human lung cancer

Chávez-López MDG, Zúñiga-García V, Hernández-Gallegos E, Vera E, Chasiquiza-Anchatuña CA, Viteri-Yánez M, Sanchez-Ramos J, Garrido E, Camacho J

OncoTargets and Therapy 2017, 10:5795-5803

Published Date: 6 December 2017

Original Research

CircRNA_100782 regulates pancreatic carcinoma proliferation through the IL6-STAT3 pathway

Chen G, Shi Y, Zhang Y, Sun J

OncoTargets and Therapy 2017, 10:5783-5794

Published Date: 5 December 2017

Original Research

Impact of aristolochic acid exposure on oncologic outcomes of upper tract urothelial carcinoma after radical nephroureterectomy

Zhong W, Zhang L, Ma J, Shao S, Lin R, Li X, Xiong G, Fang D, Zhou L

OncoTargets and Therapy 2017, 10:5775-5782

Published Date: 5 December 2017

Original Research

Hopea odorata extract inhibits hepatocellular carcinoma via induction of caspase-dependent apoptosis

Nguyen ST, Huynh KL, Nguyen HL, Nguyen Thi Thanh M, Nguyen Trung N, Nguyen Xuan H, Ngoc KP, Truong Dinh K, Pham PV

OncoTargets and Therapy 2017, 10:5765-5774

Published Date: 4 December 2017

Original Research

Differential radiation response between normal astrocytes and glioma cells revealed by comparative transcriptome analysis

Gong L, Gu JC, Ge JW, Wu X, Zhang C, Yang C, Weng WJ, Gao GY, Feng JF, Mao Q

OncoTargets and Therapy 2017, 10:5755-5764

Published Date: 4 December 2017

Review

Advances in T-cell checkpoint immunotherapy for head and neck squamous cell carcinoma

Qi X, Jia B, Zhao X, Yu D

OncoTargets and Therapy 2017, 10:5745-5754

Published Date: 1 December 2017

Original Research

Cisplatin versus carboplatin in combination with paclitaxel as neoadjuvant regimen for triple negative breast cancer

Huang L, Liu Q, Chen S, Shao ZM

OncoTargets and Therapy 2017, 10:5739-5744

Published Date: 1 December 2017

Original Research

Predictive value of interim PET/CT visual interpretation in the prognosis of patients with aggressive non-Hodgkin’s lymphoma

Liao CC, Qin YY, Tan XH, Hu JJ, Tang Q, Rong Y, Cen H, Li LQ

OncoTargets and Therapy 2017, 10:5727-5738

Published Date: 30 November 2017

Original Research

Low expression of DAB2IP predicts an unfavorable prognosis in human bladder carcinoma

Zheng L, Chen K, Zhu L, Su D, Cheng G

OncoTargets and Therapy 2017, 10:5719-5726

Published Date: 29 November 2017

Original Research

Expression patterns of microRNA-329 and its clinical performance in diagnosis and prognosis of breast cancer

Li P, Dong J, Zhou X, Sun W, Huang H, Chen T, Ye B, Zheng Z, Lu M

OncoTargets and Therapy 2017, 10:5711-5718

Published Date: 28 November 2017

Original Research

Antitumor effects of pristimerin on human osteosarcoma cells in vitro and in vivo

Mori Y, Shirai T, Terauchi R, Tsuchida S, Mizoshiri N, Hayashi D, Arai Y, Kishida T, Mazda O, Kubo T

OncoTargets and Therapy 2017, 10:5703-5710

Published Date: 28 November 2017

Original Research

Diagnostic significance of circulating long noncoding RNA PCAT6 in patients with non-small cell lung cancer

Wan L, Zhang L, Fan K, Wang JJ

OncoTargets and Therapy 2017, 10:5695-5702

Published Date: 28 November 2017

Original Research

PBX3 is associated with proliferation and poor prognosis in patients with cervical cancer

Li H, Sun G, Liu C, Wang J, Jing R, Wang J, Zhao X, Xu X, Yang Y

OncoTargets and Therapy 2017, 10:5685-5694

Published Date: 27 November 2017

Original Research

The combination of systemic therapy and locoregional radiotherapy prolongs survival in newly diagnosed metastatic nasopharyngeal carcinoma patients

Yin Z, Zhang X, Wang Y, Wang P, Yuan Z

OncoTargets and Therapy 2017, 10:5677-5683

Published Date: 27 November 2017

Original Research

MicroRNA-211 promotes non-small-cell lung cancer proliferation and invasion by targeting MxA

Kang M, Shi J, Peng N, He S

OncoTargets and Therapy 2017, 10:5667-5675

Published Date: 28 November 2017

Original Research

The combination therapy of salinomycin and gefitinib using poly(D,L-lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles for targeting both lung cancer stem cells and cancer cells

Zhang Y, Zhang Q, Sun J, Liu H, Li Q

OncoTargets and Therapy 2017, 10:5653-5666

Published Date: 27 November 2017

Original Research

18F-fluorodeoxyglucose uptake predicts MET expression in lung adenocarcinoma

An S, Zhou X, Liu J, Huang G

OncoTargets and Therapy 2017, 10:5643-5651

Published Date: 27 November 2017

Original Research

Microtubule-targeting agents can sensitize cancer cells to ionizing radiation by an interphase-based mechanism

Markowitz D, Ha G, Ruggieri R, Symons M

OncoTargets and Therapy 2017, 10:5633-5642

Published Date: 24 November 2017

Original Research

Effects of insulin analogs and glucagon-like peptide-1 receptor agonists on proliferation and cellular energy metabolism in papillary thyroid cancer

He L, Zhang S, Zhang X, Liu R, Guan H, Zhang H

OncoTargets and Therapy 2017, 10:5621-5631

Published Date: 24 November 2017

Original Research

RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer

Xie SY, Li G, Han C, Yu YY, Li N

OncoTargets and Therapy 2017, 10:5605-5619

Published Date: 23 November 2017

Original Research

Simultaneous overexpression of miR-126 and miR-34a induces a superior antitumor efficacy in pancreatic adenocarcinoma

Feng SD, Mao ZM, Liu CY, Nie YS, Sun B, Guo MG, Su CQ

OncoTargets and Therapy 2017, 10:5591-5604

Published Date: 23 November 2017

Original Research

Clinical application of carbon nanoparticles in curative resection for colorectal carcinoma

Wang LY, Li JH, Zhou X, Zheng QC, Cheng X

OncoTargets and Therapy 2017, 10:5585-5589

Published Date: 22 November 2017

Original Research

Lymphocyte-to-monocyte ratio before chemoradiotherapy represents a prognostic predictor for locally advanced rectal cancer

Deng YX, Lin JZ, Peng JH, Zhao YJ, Sui QQ, Wu XJ, Lu ZH, Gao YH, Zeng ZF, Pan ZZ

OncoTargets and Therapy 2017, 10:5575-5583

Published Date: 22 November 2017

Original Research

The clinical significance of CXCL5 in non-small cell lung cancer

Wu K, Yu S, Liu Q, Bai X, Zheng X, Wu K

OncoTargets and Therapy 2017, 10:5561-5573

Published Date: 21 November 2017

Original Research

Identification of hub miRNA biomarkers for bladder cancer by weighted gene coexpression network analysis

Zhao F, Ge YZ, Zhou LH, Xu LW, Xu Z, Ping WW, Wang M, Zhou CC, Wu R, Jia RP

OncoTargets and Therapy 2017, 10:5551-5559

Published Date: 22 November 2017

Original Research

Preoperative prognostic nutritional index and nomogram predicting recurrence-free survival in patients with primary non-muscle-invasive bladder cancer without carcinoma in situ

Cui J, Chen S, Bo Q, Wang S, Zhang N, Yu M, Wang W, Han J, Zhu Y, Shi B

OncoTargets and Therapy 2017, 10:5541-5550

Published Date: 21 November 2017

Original Research

Prognostic and clinicopathological significance of ubiquitin-specific protease 22 overexpression in cancers: evidence from a meta-analysis

Ao N, Wang L, Liu Y

OncoTargets and Therapy 2017, 10:5533-5540

Published Date: 21 November 2017

Original Research

The relationship between IGF2BP2 and PPARG polymorphisms and susceptibility to esophageal squamous-cell carcinomas in the eastern Chinese Han population

Qiu H, Wang Y, Kang M, Ding H, Liu C, Tang W, Xiao Z, Chen Y

OncoTargets and Therapy 2017, 10:5525-5532

Published Date: 21 November 2017

Review

The crossroads of breast cancer progression: insights into the modulation of major signaling pathways

Velloso FJ, Bianco AFR, Farias JO, Torres NEC, Ferruzo PY, Anschau V, Jesus-Ferreira HC, Chang TH, Sogayar MC, Zerbini LF, Correa RG

OncoTargets and Therapy 2017, 10:5491-5524

Published Date: 20 November 2017

Corrigendum

Toll-like receptors 7 and 8 expression correlates with the expression of immune biomarkers and positively predicts the clinical outcome of patients with melanoma [Corrigendum]

Zhang MC, Yan ZL, Wang JJ, Yao XQ

OncoTargets and Therapy 2017, 10:5489-5490

Published Date: 16 November 2017

Original Research

Cytomembranic PD-L1 expression in locoregionally advanced nasopharyngeal carcinoma

Zheng L, Cao C, Cheng G, Hu Q, Chen X

OncoTargets and Therapy 2017, 10:5483-5487

Published Date: 16 November 2017

Original Research

Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-κB/COX-2 signaling pathways

Zhao J, Zhu J, Lv X, Xing J, Liu S, Chen C, Xu Y

OncoTargets and Therapy 2017, 10:5471-5482

Published Date: 15 November 2017

Original Research

Identification of COX5B as a novel biomarker in high-grade glioma patients

Hu T, Xi J

OncoTargets and Therapy 2017, 10:5463-5470

Published Date: 15 November 2017

Case report

Male occult triple-negative breast cancer with dermatomyositis: a case report and review of the literature

Zhang L, Zhang C, Yang Z, He M, Zhang L, Ezzat S, Liang X

OncoTargets and Therapy 2017, 10:5459-5462

Published Date: 14 November 2017

Original Research

Nimotuzumab combined with concurrent chemoradiotherapy benefits patients with advanced nasopharyngeal carcinoma

Li Z, Li Y, Yan S, Fu J, Zhou Q, Huang X, Shen L

OncoTargets and Therapy 2017, 10:5445-5458

Published Date: 14 November 2017

Original Research

Clinical significance of CMTM4 expression in hepatocellular carcinoma

Bei CH, Zhang Y, Wei RM, Zhu XN, Wang ZG, Zeng W, Chen QY, Tan SK

OncoTargets and Therapy 2017, 10:5439-5443

Published Date: 14 November 2017

Original Research

The effect of CYP2D6 *10 polymorphism on adjuvant tamoxifen in Asian breast cancer patients: a meta-analysis

Lu J, Li H, Guo P, Shen R, Luo Y, Ge Q, Shi WF, Li Y, Zhu W

OncoTargets and Therapy 2017, 10:5429-5437

Published Date: 13 November 2017

Case report

Effective treatment of low-dose decitabine in myelodysplastic syndrome/myeloproliferative neoplasms

Ye X, Chen D, Zheng Y, Zhu X, Fu J, Huang J

OncoTargets and Therapy 2017, 10:5425-5428

Published Date: 13 November 2017

Original Research

Expression and significance of B7-H3 and Tie-2 in the tumor vasculature of clear cell renal carcinoma

Zhang X, Ji J, Zhang G, Fang C, Jiang F, Ma S, Hou J

OncoTargets and Therapy 2017, 10:5417-5424

Published Date: 13 November 2017

Original Research

In vitro study on anti-cancer properties of genistein in tongue cancer

Ardito F, Pellegrino MR, Perrone D, Troiano G, Cocco A, Lo Muzio L

OncoTargets and Therapy 2017, 10:5405-5415

Published Date: 13 November 2017

Original Research

Therapeutic efficacy and safety of combined BRAF and MEK inhibition in patients with malignant melanoma: a meta-analysis

Chen P, Chen FC, Zhou BH

OncoTargets and Therapy 2017, 10:5391-5403

Published Date: 13 November 2017

Original Research

LncRNA NEAT1 contributes to paclitaxel resistance of ovarian cancer cells by regulating ZEB1 expression via miR-194

An J, Lv W, Zhang Y

OncoTargets and Therapy 2017, 10:5377-5390

Published Date: 10 November 2017

Original Research

The effect of antiviral therapy on patients with hepatitis B virus-related hepatocellular carcinoma after curative resection: a systematic review and meta-analysis

Chen X, Cheng J, Huang A, Zhang X, Wang J, Fan J, Zhou J, Yang X

OncoTargets and Therapy 2017, 10:5363-5375

Published Date: 10 November 2017

Original Research

LncRNA expression and implication in osteosarcoma: a systematic review and meta-analysis

Wang Y, Huang YL, Xiang P, Tian W

OncoTargets and Therapy 2017, 10:5355-5361

Published Date: 9 November 2017

Review

Amatuximab and novel agents targeting mesothelin for solid tumors

Baldo P, Cecco S

OncoTargets and Therapy 2017, 10:5337-5353

Published Date: 8 November 2017

Original Research

Interleukin-6 upregulates SOX18 expression in osteosarcoma

Wu Z, Yang W, Liu J, Zhang F

OncoTargets and Therapy 2017, 10:5329-5336

Published Date: 8 November 2017

Original Research

FGF2 promotes metastasis of uveal melanoma cells via store-operated calcium entry

Wang Y, Bao X, Zhang Z, Sun Y, Zhou X

OncoTargets and Therapy 2017, 10:5317-5328

Published Date: 8 November 2017

Original Research

Primary site surgery for metastatic adrenocortical carcinoma improves survival outcomes: an analysis of a population-based database

Wang S, Gao W, Chen S, Bai L, Luo L, Zheng X, Luo Y

OncoTargets and Therapy 2017, 10:5311-5315

Published Date: 8 November 2017

Original Research

UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis

Wang B, Shen J, Wang J

OncoTargets and Therapy 2017, 10:5303-5309

Published Date: 6 November 2017

Original Research

The associations between common SNPs of EFEMP1 gene and glioma risk in Chinese population

Hu J, Dong D, Lu DD

OncoTargets and Therapy 2017, 10:5297-5302

Published Date: 6 November 2017

Clinical Trial Report

Analysis of the factors affecting the safety of robotic stereotactic body radiation therapy for hepatocellular carcinoma patients

Liu XJ, Song YC, Liang P, Su TS, Zhang HJ, Zhao XZ, Yuan ZY, Wang P

OncoTargets and Therapy 2017, 10:5289-5295

Published Date: 6 November 2017

Original Research

PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells

Guo L, Huang S, Wang X

OncoTargets and Therapy 2017, 10:5281-5288

Published Date: 3 November 2017

Original Research

S100A16, a promising candidate as a prognostic marker for platinum-based adjuvant chemotherapy in resected lung adenocarcinoma

Katono K, Sato Y, Kobayashi M, Nagashio R, Ryuge S, Igawa S, Ichinoe M, Murakumo Y, Saegusa M, Masuda N

OncoTargets and Therapy 2017, 10:5273-5279

Published Date: 2 November 2017

Original Research

Association of GEMIN4 gene polymorphism and the risk of cancer: a meta-analysis

Wu N, Zhang X, Tian J, Yu S, Qiao Y

OncoTargets and Therapy 2017, 10:5263-5271

Published Date: 2 November 2017

Original Research

Prognostic value of the C-reactive protein to albumin ratio: a novel inflammation-based prognostic indicator in osteosarcoma

Li YJ, Yao K, Lu MX, Zhang WB, Xiao C, Tu CQ

OncoTargets and Therapy 2017, 10:5255-5261

Published Date: 2 November 2017

Original Research

Identification and validation of potential prognostic gene biomarkers for predicting survival in patients with acute myeloid leukemia

Huang R, Liao XW, Li Q

OncoTargets and Therapy 2017, 10:5243-5254

Published Date: 2 November 2017

Case report

Progression-free survival of up to 8 months of an advanced intrahepatic cholangiocarcinoma patient treated with apatinib: a case report

Ma FC, Yu Q, Zeng ZM, He RQ, Mo CH, Zhong JC, Ma J, Feng ZB, Chen G, Hu XH

OncoTargets and Therapy 2017, 10:5237-5242

Published Date: 1 November 2017

Original Research

MicroRNAs as a novel class of diagnostic biomarkers for the detection of osteosarcoma: a meta-analysis

Liu H, Li P, Chen L, Jian C, Li ZH, Yu AX

OncoTargets and Therapy 2017, 10:5229-5236

Published Date: 1 November 2017

Review

Cancer cell dormancy: mechanisms and implications of cancer recurrence and metastasis

Gao XL, Zhang M, Tang YL, Liang XH

OncoTargets and Therapy 2017, 10:5219-5228

Published Date: 27 October 2017

Original Research

Matrine suppresses the migration and invasion of NSCLC cells by inhibiting PAX2-induced epithelial-mesenchymal transition

Yang J, He D, Peng Y, Zhong HZ, Deng YH, Yu Z, Guan C, Zuo Y, Xu Z

OncoTargets and Therapy 2017, 10:5209-5217

Published Date: 27 October 2017

Review

Current status of poly(ADP-ribose) polymerase inhibitors and future directions

Ohmoto A, Yachida S

OncoTargets and Therapy 2017, 10:5195-5208

Published Date: 26 October 2017

Original Research

The expression profile and clinical significance of circRNA0003906 in colorectal cancer

Zhuo F, Lin HS, Chen ZX, Huang ZJ, Hu JP

OncoTargets and Therapy 2017, 10:5187-5193

Published Date: 25 October 2017

Original Research

Frequency and clinical relevance of EGFR mutations and EML4–ALK translocations in octogenarians with non-small cell lung cancer

Tufman A, Kahnert K, Duell T, Kauffmann-Guerrero D, Milger K, Schneider C, Stump J, Syunyaeva Z, Huber RM, Reu S

OncoTargets and Therapy 2017, 10:5179-5186

Published Date: 25 October 2017

Original Research

Impact of hypertrophic pulmonary osteoarthropathy on patients with lung cancer

Fang YH, Hsu CC, Hsieh MJ, Hung MS, Tsai YH, Lin YC

OncoTargets and Therapy 2017, 10:5173-5177

Published Date: 25 October 2017

Case report

Low-grade central osteosarcoma in proximal humerus: a rare entity

Tang F, Min L, Zhou Y, Luo Y, Tu CQ

OncoTargets and Therapy 2017, 10:5165-5172

Published Date: 24 October 2017

Original Research

Overexpression of MPC1 inhibits the proliferation, migration, invasion, and stem cell-like properties of gastric cancer cells

Zhou X, Xiong ZJ, Xiao SM, Zhou J, Ding Z, Tang LC, Chen XD, Xu R, Zhao P

OncoTargets and Therapy 2017, 10:5151-5163

Published Date: 24 October 2017

Original Research

LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis

Wang P, Chen D, Ma H, Li Y

OncoTargets and Therapy 2017, 10:5137-5149

Published Date: 25 October 2017

Original Research

Increased histone deacetylase 6 expression serves as a favorable prognostic factor for diffuse large B-cell lymphoma

Lin X, Cai L, Qian Z, Wang C, Sun N, Sun X, Huang H, Guo W, Lin H, Yao R

OncoTargets and Therapy 2017, 10:5129-5136

Published Date: 24 October 2017

Original Research

Long noncoding RNA and mRNA profiling in MDA-MB-231 cells following RNAi-mediated knockdown of SIRT7

Chen KL, Li L, Wang YR, Li CM, Badri TM, Wang GL

OncoTargets and Therapy 2017, 10:5115-5128

Published Date: 24 October 2017

Original Research

Preventive effect of kampo medicine (hangeshashin-to, TJ-14) plus minocycline against afatinib-induced diarrhea and skin rash in patients with non-small cell lung cancer

Ichiki M, Wataya H, Yamada K, Tsuruta N, Takeoka H, Okayama Y, Sasaki J, Hoshino T

OncoTargets and Therapy 2017, 10:5107-5113

Published Date: 24 October 2017

Original Research

The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study

Schiegnitz E, Kämmerer PW, Schön H, Gülle C, Berres M, Sagheb K, Al-Nawas B

OncoTargets and Therapy 2017, 10:5099-5105

Published Date: 24 October 2017

Original Research

Association of PTEN expression with biochemical recurrence in prostate cancer: results based on previous reports

Xie HJ, Xie B, Liu CY, Wang J, Xu Y

OncoTargets and Therapy 2017, 10:5089-5097

Published Date: 24 October 2017

Original Research

Developing a novel dual PI3K–mTOR inhibitor from the prodrug of a metabolite

Zhou Y, Zhang GY, Wang F, Wang J, Ding YW, Li XY, Shi CT, Li JK, Shih CK, You S

OncoTargets and Therapy 2017, 10:5077-5087

Published Date: 20 October 2017

Original Research

FcγRIIA and IIIA polymorphisms predict clinical outcome of trastuzumab-treated metastatic gastric cancer

Wang D, Wei X, Wang Z, Lu Y, Shi S, Wang N, Qiu M, Wang F, Wang RJ, Li Y, Xu R

OncoTargets and Therapy 2017, 10:5065-5076

Published Date: 19 October 2017

Review

Practical management of adverse events associated with cabozantinib treatment in patients with renal-cell carcinoma

Gerendash BS, Creel PA

OncoTargets and Therapy 2017, 10:5053-5064

Published Date: 19 October 2017

Case report

Adult acute megakaryoblastic leukemia: rare association with cytopenias of undetermined significance and p210 and p190 BCR–ABL transcripts

Dima D, Oprita L, Rosu AM, Trifa A, Selicean C, Moisoiu V, Frinc I, Zdrenghea M, Tomuleasa C

OncoTargets and Therapy 2017, 10:5047-5051

Published Date: 19 October 2017

Original Research

Clinical significance of Fusobacterium nucleatum, epithelial–mesenchymal transition, and cancer stem cell markers in stage III/IV colorectal cancer patients

Yan X, Liu L, Li H, Qin H, Sun Z

OncoTargets and Therapy 2017, 10:5031-5046

Published Date: 17 October 2017

Original Research

Impact of prior therapies on everolimus activity: an exploratory analysis of RADIANT-4

Buzzoni R, Carnaghi C, Strosberg J, Fazio N, Singh S, Herbst F, Ridolfi A, Pavel ME, Wolin EM, Valle JW, Oh DY, Yao JC, Pommier R

OncoTargets and Therapy 2017, 10:5013-5030

Published Date: 16 October 2017

Original Research

Prognostic value of PD-L1 overexpression for pancreatic cancer: evidence from a meta-analysis

Zhuan-Sun Y, Huang F, Feng M, Zhao X, Chen W, Zhu Z, Zhang S

OncoTargets and Therapy 2017, 10:5005-5012

Published Date: 16 October 2017

Case Series

Novel strategy of stents in thyroid mass: a case series report of managing severely dyspneic patients

Bhandari A, Wang Y, Lv S, Xia E, Wang O

OncoTargets and Therapy 2017, 10:4997-5004

Published Date: 16 October 2017

Original Research

Apatinib plus icotinib in treating advanced non-small cell lung cancer after icotinib treatment failure: a retrospective study

Xu J, Liu X, Yang S, Zhang X, Shi Y

OncoTargets and Therapy 2017, 10:4989-4995

Published Date: 13 October 2017

Original Research

Clinical outcome and toxicity evaluation of simultaneous integrated boost pelvic IMRT/VMAT at different dose levels combined with androgen deprivation therapy in prostate cancer patients

Daoud MA, Aboelnaga EM, Alashry MS, Fathy S, Aletreby MA

OncoTargets and Therapy 2017, 10:4981-4988

Published Date: 12 October 2017

Original Research

Mutation analysis and copy number alterations of KIF23 in non-small-cell lung cancer exhibiting KIF23 over-expression

Vikberg AL, Vooder T, Lokk K, Annilo T, Golovleva I

OncoTargets and Therapy 2017, 10:4969-4979

Published Date: 11 October 2017

Original Research

Molecular alterations and clinical prognostic factors for cholangiocarcinoma in Thai population

Trachu N, Sirachainan E, Larbcharoensub N, Rattanadech W, Detarkom S, Monnamo N, Kamprerasart K, MunTham D, Sukasem C, Reungwetwattana T

OncoTargets and Therapy 2017, 10:4955-4968

Published Date: 11 October 2017

Original Research

Upregulation of long noncoding RNA LOC440040 promotes tumor progression and predicts poor prognosis in patients with prostate cancer

Zhang C, Liu C, Wu J, Zheng Y, Xu H, Cheng G, Hua L

OncoTargets and Therapy 2017, 10:4945-4954

Published Date: 11 October 2017

Original Research

The expression of microRNA-324-3p as a tumor suppressor in nasopharyngeal carcinoma and its clinical significance

Zhang H, Sun Y, Li J, Huang L, Tan S, Yang F, Li H

OncoTargets and Therapy 2017, 10:4935-4943

Published Date: 11 October 2017

Original Research

Identification of key pathways and genes with aberrant methylation in prostate cancer using bioinformatics analysis

Singh AN, Sharma N

OncoTargets and Therapy 2017, 10:4925-4933

Published Date: 10 October 2017

Original Research

Low platelet count is potentially the most important contributor to severe bleeding in patients newly diagnosed with acute promyelocytic leukemia

Song Y, Peng P, Qiao C, Zhang R, Li J, Lu H

OncoTargets and Therapy 2017, 10:4917-4924

Published Date: 9 October 2017

Original Research

NEAT1 regulates cell proliferation and apoptosis of ovarian cancer by miR-34a-5p/BCL2

Ding N, Wu H, Tao T, Peng E

OncoTargets and Therapy 2017, 10:4905-4915

Published Date: 6 October 2017

Original Research

let-7d suppresses proliferation and invasion and promotes apoptosis of meningioma by targeting AEG-1

Li H, Zhao J

OncoTargets and Therapy 2017, 10:4895-4904

Published Date: 6 October 2017

Original Research

Real-world experience of everolimus as second-line treatment in metastatic renal cell cancer after failure of pazopanib

Koutsoukos K, Bamias A, Tzannis K, Espinosa Montaño M, Bozionelou V, Christodoulou C, Stefanou D, Kalofonos H, Duran I, Papazisis K

OncoTargets and Therapy 2017, 10:4885-4893

Published Date: 6 October 2017

Original Research

Crizotinib, a MET inhibitor, inhibits growth, migration, and invasion of breast cancer cells in vitro and synergizes with chemotherapeutic agents

Ayoub NM, Al-Shami KM, Alqudah MA, Mhaidat NM

OncoTargets and Therapy 2017, 10:4869-4883

Published Date: 5 October 2017

Original Research

ER-positive breast cancer patients with more than three positive nodes or grade 3 tumors are at high risk of late recurrence after 5-year adjuvant endocrine therapy

Song F, Zhang J, Li S, Wu J, Jin T, Qin J, Wang Y, Wang M, Xu J

OncoTargets and Therapy 2017, 10:4859-4867

Published Date: 3 October 2017

Original Research

TERT-CLPTM1 locus polymorphism (rs401681) is associated with the prognosis of hepatocellular carcinoma

Lee HW, Park W, Heo Y, Park TI, Park SY, Lee J

OncoTargets and Therapy 2017, 10:4853-4858

Published Date: 3 October 2017

Original Research

Significant association of the EXO1 rs851797 polymorphism with clinical outcome of ovarian cancer

Shi T, Jiang R, Wang P, Xu Y, Yin S, Cheng X, Zang R

OncoTargets and Therapy 2017, 10:4841-4851

Published Date: 3 October 2017

Review

Comparison of microwave ablation and hepatic resection for hepatocellular carcinoma: a meta-analysis

Zhang M, Ma H, Zhang J, He L, Ye X, Li X

OncoTargets and Therapy 2017, 10:4829-4839

Published Date: 3 October 2017

Review

Theranostics in nuclear medicine practice

Yordanova A, Eppard E, Kürpig S, Bundschuh RA, Schönberger S, Gonzalez-Carmona M, Feldmann G, Ahmadzadehfar H, Essler M

OncoTargets and Therapy 2017, 10:4821-4828

Published Date: 3 October 2017

Original Research

Low dose of kaempferol suppresses the migration and invasion of triple-negative breast cancer cells by downregulating the activities of RhoA and Rac1

Li S, Yan T, Deng R, Jiang X, Xiong H, Wang Y, Yu Q, Wang X, Chen C, Zhu Y

OncoTargets and Therapy 2017, 10:4809-4819

Published Date: 3 October 2017

Review

Is this the end of cytotoxic chemotherapy in Merkel cell carcinoma?

Rabinowits G

OncoTargets and Therapy 2017, 10:4803-4807

Published Date: 28 September 2017

Original Research

Clinicopathological features and prognoses in younger and older patients with gastric cancer

Song S, Li C, Li S, Cong X, Xue Y

OncoTargets and Therapy 2017, 10:4795-4802

Published Date: 27 September 2017

Original Research

Sitting time and occupational and recreational physical activity in relation to the risk of esophageal squamous cell carcinoma

Chen P, Song Q, Han J, Xu H, Chen T, Xu J, Cheng Y

OncoTargets and Therapy 2017, 10:4787-4794

Published Date: 27 September 2017

Original Research

Yttrium-90 radioembolization of unresectable hepatocellular carcinoma – a single center experience

Meyer C, Pieper CC, Ahmadzadehfar H, Lampe NA, Matuschek EME, Maschke TA, Enkirch SJ, Essler M, Spengler U, Schild HH

OncoTargets and Therapy 2017, 10:4773-4785

Published Date: 26 September 2017

Original Research

Molecular classification of esophagogastric junction carcinoma correlated with prognosis

Zou L, Wu Y, Ma K, Fan Y, Dong D, Geng N, Li E

OncoTargets and Therapy 2017, 10:4765-4772

Published Date: 25 September 2017

Original Research

HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a

Wang Q, Jiang S, Song A, Hou S, Wu Q, Qi L, Gao X

OncoTargets and Therapy 2017, 10:4753-4763

Published Date: 28 September 2017

Clinical Trial Report

DNA hypermethylated status and gene expression of PAX1/SOX1 in patients with colorectal carcinoma

Huang J, Tan ZR, Yu J, Li H, Lv Q, Shao Y, Zhou H

OncoTargets and Therapy 2017, 10:4739-4751

Published Date: 26 September 2017

Original Research

Characteristics and mutation analysis of Ph-positive leukemia patients with T315I mutation receiving tyrosine kinase inhibitors

Xu PP, Guo D, Shao XY, Peng MX, Chen B

OncoTargets and Therapy 2017, 10:4731-4738

Published Date: 25 September 2017

Original Research

Quercetin inhibits epithelial–mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial–mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells

Yu D, Ye T, Xiang Y, Shi Z, Zhang J, Lou B, Zhang F, Chen B, Zhou M

OncoTargets and Therapy 2017, 10:4719-4729

Published Date: 25 September 2017

Review

Current advances of long non-coding RNA highly upregulated in liver cancer in human tumors

Ma Z, Huang H, Xu Y, He X, Wang J, Hui B, Ji H, Zhou J, Wang K

OncoTargets and Therapy 2017, 10:4711-4717

Published Date: 25 September 2017

Original Research

RNAi-mediated knockdown of CAIX enhances the radiosensitivity of nasopharyngeal carcinoma cell line, CNE-2

Jiang L, Xu G, Li Z, Zeng X, Li Z, Liu J, Mei L, Li X

OncoTargets and Therapy 2017, 10:4701-4709

Published Date: 25 September 2017

Original Research

High expression of Sam68 in sacral chordomas is associated with worse clinical outcomes

Wen H, Li P, Ma H, Zheng J, Yu Y, Lv G

OncoTargets and Therapy 2017, 10:4691-4700

Published Date: 22 September 2017

Case report

Clinical effects of autologous cytokine-induced killer cell-based immunotherapy in the treatment of endometrial cancer: a case report and literature review

Zhang Y, Qi Y, Wang A, Ma B, Fu X, Zhao L, Gao Q

OncoTargets and Therapy 2017, 10:4687-4690

Published Date: 22 September 2017

Review

Targeting the androgen receptor in triple-negative breast cancer: current perspectives

Mina A, Yoder R, Sharma P

OncoTargets and Therapy 2017, 10:4675-4685

Published Date: 20 September 2017

Original Research

Clinical significance of SLP-2 in hepatocellular carcinoma tissues and its regulation in cancer cell proliferation, migration, and EMT

Huang Y, Chen Y, Lin X, Lin Q, Han M, Guo G

OncoTargets and Therapy 2017, 10:4665-4673

Published Date: 20 September 2017

Original Research

DNA ploidy and S-phase fraction analysis in peritoneal carcinomatosis from ovarian cancer: correlation with clinical pathological factors and response to chemotherapy

Carloni S, Gallerani G, Tesei A, Scarpi E, Verdecchia GM, Virzì S, Fabbri F, Arienti C

OncoTargets and Therapy 2017, 10:4657-4664

Published Date: 20 September 2017

Original Research

The effects of nonsteroidal anti-inflammatory drugs in the incident and recurrent risk of hepatocellular carcinoma: a meta-analysis

Pang Q, Jin H, Qu K, Man Z, Wang Y, Yang S, Zhou L, Liu H

OncoTargets and Therapy 2017, 10:4645-4656

Published Date: 20 September 2017

Original Research

HIF pathway and c-Myc as biomarkers for response to sunitinib in metastatic clear-cell renal cell carcinoma

Maroto P, Esteban E, Fernández Parra E, Mendez-Vidal MJ, Domenech M, Pérez-Valderrama B, Calderero V, Pérez-Gracia JL, Grande E, Algaba F

OncoTargets and Therapy 2017, 10:4635-4643

Published Date: 20 September 2017

Original Research

NANOG as an adverse predictive marker in advanced non–small cell lung cancer treated with platinum-based chemotherapy

Chang B, Park MJ, Choi SI, In KH, Kim CH, Lee SH

OncoTargets and Therapy 2017, 10:4625-4633

Published Date: 19 September 2017

Review

The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer

Mahecha AM, Wang H

OncoTargets and Therapy 2017, 10:4617-4624

Published Date: 19 September 2017

Corrigendum

Effect of temozolomide on survival in elderly patients with glioblastoma and impaired performance status: a propensity score-matching analysis [Corrigendum]

Liu Y, Liu P, Shao W, Du H, Li Z, Guo C, Li Z

OncoTargets and Therapy 2017, 10:4615-4616

Published Date: 18 September 2017

Original Research

EGFR with TKI-sensitive mutations in exon 19 is highly expressed and frequently detected in Chinese patients with lung squamous carcinoma

Memon AA, Zhang HP, Gu Y, Luo Q, Shi JJ, Deng Z, Ma J, Ma W

OncoTargets and Therapy 2017, 10:4607-4613

Published Date: 18 September 2017

Review

Profile of trifluridine/tipiracil hydrochloride in the treatment of metastatic colorectal cancer: efficacy, safety, and place in therapy

Sunakawa Y, Izawa N, Mizukami T, Horie Y, Hirakawa M, Arai H, Ogura T, Tsuda T, Nakajima TE

OncoTargets and Therapy 2017, 10:4599-4605

Published Date: 15 September 2017

Review

Diagnostic and prognostic value of carcinoembryonic antigen in pancreatic cancer: a systematic review and meta-analysis

Meng Q, Shi S, Liang C, Liang D, Xu W, Ji S, Zhang B, Ni Q, Xu J, Yu X

OncoTargets and Therapy 2017, 10:4591-4598

Published Date: 15 September 2017

Original Research

DNA fragmentation factors 40 and 45 (DFF40/DFF45) and B-cell lymphoma 2 (Bcl-2) protein are underexpressed in uterine leiomyosarcomas and may predict survival

Banas T, Pitynski K, Okon K, Czerw A

OncoTargets and Therapy 2017, 10:4579-4589

Published Date: 14 September 2017

Original Research

Polygonatum odoratum lectin promotes BECN1 expression and induces autophagy in malignant melanoma by regulation of miR1290

Luan W, Qian Y, Ni X, Chanda TK, Xia Y, Wang J, Yan Y, Xu B

OncoTargets and Therapy 2017, 10:4569-4577

Published Date: 14 September 2017

Original Research

CYP19A1 gene polymorphism and colorectal cancer etiology in Saudi population: case–control study

Al-Mukaynizi FB, Alanazi M, Al-Daihan S, Parine NR, Almadi M, Aljebreen A, Azzam N, Alharbi O, Arafah M, Warsy A

OncoTargets and Therapy 2017, 10:4559-4567

Published Date: 14 September 2017

Case report

Case report of a KIT-mutated melanoma patient with an excellent response to apatinib and temozolomide combination therapy

Luo C, Shen JY, Ying J, Fang XH, Wang XH, Fu ZX, Liu P

OncoTargets and Therapy 2017, 10:4553-4557

Published Date: 14 September 2017

Review

Clinicopathological significance of HSP27 in gastric cancer: a meta-analysis

Ge H, He X, Guo L, Yang X

OncoTargets and Therapy 2017, 10:4543-4551

Published Date: 13 September 2017

Review

Anaplastic lymphoma kinase inhibition in metastatic non-small cell lung cancer: clinical impact of alectinib

Muller IB, de Langen AJ, Giovannetti E, Peters GJ

OncoTargets and Therapy 2017, 10:4535-4541

Published Date: 13 September 2017

Review

Biomarkers for early diagnosis, prognosis, prediction, and recurrence monitoring of non-small cell lung cancer

Tang Y, Qiao G, Xu E, Xuan Y, Liao M, Yin G

OncoTargets and Therapy 2017, 10:4527-4534

Published Date: 12 September 2017

Case report

Adenocarcinoma of the lung with EGFR gene mutation and subsequent resistance mechanisms exploration: case report

Xu L, Wang QZ, Wu L

OncoTargets and Therapy 2017, 10:4517-4525

Published Date: 12 September 2017

Original Research

The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive

Yu S, Zhang Y, Pan YJ, Cheng C, Sun YH, Chen HQ

OncoTargets and Therapy 2017, 10:4507-4515

Published Date: 12 September 2017

Original Research

Genome-scale analysis to identify prognostic markers in patients with early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy

Liao X, Huang K, Huang R, Liu X, Han C, Yu L, Yu T, Yang C, Wang X, Peng T

OncoTargets and Therapy 2017, 10:4493-4506

Published Date: 12 September 2017

Original Research

Predictive factors and prognosis for recurrent laryngeal nerve invasion in papillary thyroid carcinoma

Chen W, Lei J, You J, Lei Y, Li Z, Gong R, Tang H, Zhu J

OncoTargets and Therapy 2017, 10:4485-4491

Published Date: 11 September 2017

Original Research

Cervical level IIb metastases in squamous cell carcinoma of the oral cavity: a systematic review and meta-analysis

Kou Y, Zhao T, Huang S, Liu J, Duan W, Wang Y, Wang Z, Li D, Ning C, Sun C

OncoTargets and Therapy 2017, 10:4475-4483

Published Date: 11 September 2017

Original Research

Oncogenic role of microRNA-20a in human multiple myeloma

Wang T, Tao W, Zhang L, Li SL

OncoTargets and Therapy 2017, 10:4465-4474

Published Date: 11 September 2017

Original Research

miR-509-5p inhibits cellular proliferation and migration via targeting MDM2 in pancreatic cancer cells

Li X, Li Y, Wan L, Chen R, Chen F

OncoTargets and Therapy 2017, 10:4455-4464

Published Date: 11 September 2017

Original Research

Targeted interfering DEP domain containing 1 protein induces apoptosis in A549 lung adenocarcinoma cells through the NF-κB signaling pathway

Wang Q, Li A, Jin J, Huang G

OncoTargets and Therapy 2017, 10:4443-4454

Published Date: 11 September 2017

Original Research

Intraoperative measurement of thyroglobulin in lymph node aspirates for the detection of metastatic papillary thyroid carcinoma

Wang Y, Liu Y, Wang X, Li X, Jiang R, He X

OncoTargets and Therapy 2017, 10:4435-4441

Published Date: 11 September 2017

Original Research

Prognostic immune-related gene models for breast cancer: a pooled analysis

Zhao J, Wang Y, Lao Z, Liang S, Hou J, Yu Y, Yao H, You N, Chen K

OncoTargets and Therapy 2017, 10:4423-4433

Published Date: 11 September 2017

Original Research

Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer

Yang F, Gao JY, Chen H, Du ZH, Zhang XQ, Gao W

OncoTargets and Therapy 2017, 10:4413-4422

Published Date: 11 September 2017

Review

Marketed drugs used for the management of hypercholesterolemia as anticancer armament

Papanagnou P, Stivarou T, Papageorgiou I, Papadopoulos GE, Pappas A

OncoTargets and Therapy 2017, 10:4393-4411

Published Date: 8 September 2017

Original Research

Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

Hu B, Lv X, Gao F, Chen S, Wang S, Qing X, Liu J, Wang B, Shao Z

OncoTargets and Therapy 2017, 10:4379-4391

Published Date: 8 September 2017

Original Research

Genetic variants in long noncoding RNA H19 contribute to the risk of breast cancer in a southeast China Han population

Lin Y, Fu F, Chen Y, Qiu W, Lin S, Yang P, Huang M, Wang C

OncoTargets and Therapy 2017, 10:4369-4378

Published Date: 7 September 2017

Original Research

Biomarker analysis and clinical relevance of TK1 on the cell membrane of Burkitt’s lymphoma and acute lymphoblastic leukemia

Weagel EG, Meng W, Townsend MH, Velazquez EJ, Brog RA, Boyer MW, Weber KS, Robison RA, O'Neill KL

OncoTargets and Therapy 2017, 10:4355-4367

Published Date: 6 September 2017

Case report

Durable complete remission of poor performance status metastatic lung adenocarcinoma patient treated with second-line erlotinib: a case report

Jovanovic D, Stevic R, Velinovic M, Kontic M, Maric D, Spasic J, Radosavljevic D

OncoTargets and Therapy 2017, 10:4347-4354

Published Date: 6 September 2017

Original Research

Toll-like receptors 7 and 8 expression correlates with the expression of immune biomarkers and positively predicts the clinical outcome of patients with melanoma

Zhang MC, Yan ZL, Wang JJ, Yao XQ

OncoTargets and Therapy 2017, 10:4339-4346

Published Date: 1 September 2017

Original Research

Inhibitory effects of a selective Jak2 inhibitor on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT20 cells

Asari Y, Kageyama K, Nakada Y, Tasso M, Takayasu S, Niioka K, Ishigame N, Daimon M

OncoTargets and Therapy 2017, 10:4329-4338

Published Date: 1 September 2017

Original Research

Clinicopathological and prognostic significance of Ki-67 immunohistochemical expression in gastric cancer: a systematic review and meta-analysis

Liu G, Xiong DS, Zeng JJ, Chen BR, Huang ZJ

OncoTargets and Therapy 2017, 10:4321-4328

Published Date: 1 September 2017

Review

The role and significance of VEGFR2+ regulatory T cells in tumor immunity

Zhu PR, Hu CX, Hui KY, Jiang XD

OncoTargets and Therapy 2017, 10:4315-4319

Published Date: 1 September 2017

Original Research

Nuclear factor-kappa B1 inhibits early apoptosis of glioma cells by promoting the expression of Bcl-2

Yang TQ, Chen M, Wang YQ, Xu W, Han Y, Xu J, Xiang YJ, Yuan B, Wang HZ, Zhou YX

OncoTargets and Therapy 2017, 10:4305-4313

Published Date: 31 August 2017

Original Research

Improvement of survival for non-small cell lung cancer over time

Xia W, Yu X, Mao Q, Xia W, Wang A, Dong G, Chen B, Ma W, Xu L, Jiang F

OncoTargets and Therapy 2017, 10:4295-4303

Published Date: 29 August 2017

Original Research

Synaptotagmin-7 is overexpressed in hepatocellular carcinoma and regulates hepatocellular carcinoma cell proliferation via Chk1–p53 signaling

Jin H, Xu G, Zhang Q, Pang Q, Fang M

OncoTargets and Therapy 2017, 10:4283-4293

Published Date: 29 August 2017

Original Research

Comparison of autogeneic and allogeneic natural killer cells immunotherapy on the clinical outcome of recurrent breast cancer

Liang S, Xu K, Niu L, Wang X, Liang Y, Zhang M, Chen J, Lin M

OncoTargets and Therapy 2017, 10:4273-4281

Published Date: 28 August 2017

Original Research

Apatinib in the treatment of advanced lung adenocarcinoma with KRAS mutation

Zeng D, Wang C, Huang J, Jiang J

OncoTargets and Therapy 2017, 10:4269-4272

Published Date: 28 August 2017

Original Research

Continuous EGFR tyrosine kinase inhibitor treatment with or without chemotherapy beyond gradual progression in non-small cell lung cancer patients

Peng L, Wang YN, Tang YM, Zeng L, Liu JF, Zeng Z, Liu J, Shi P, Ye XH, Zhao Q

OncoTargets and Therapy 2017, 10:4261-4267

Published Date: 28 August 2017

Original Research

LEF1-AS1, a long non-coding RNA, promotes malignancy in glioblastoma

Wang J, Liu X, Yan C, Liu J, Wang S, Hong Y, Gu A, Zhao P

OncoTargets and Therapy 2017, 10:4251-4260

Published Date: 28 August 2017

Clinical Trial Report

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

Creelan BC, Gabrilovich DI, Gray JE, Williams CC, Tanvetyanon T, Haura EB, Weber JS, Gibney GT, Markowitz J, Proksch JW, Reisman SA, McKee MD, Chin MP, Meyer CJ, Antonia SJ

OncoTargets and Therapy 2017, 10:4239-4250

Published Date: 29 August 2017

Original Research

miRNA expression profiling in formalin-fixed paraffin-embedded endometriosis and ovarian cancer samples

Braicu OL, Budisan L, Buiga R, Jurj A, Achimas-Cadariu P, Pop LA, Braicu C, Irimie A, Berindan-Neagoe I

OncoTargets and Therapy 2017, 10:4225-4238

Published Date: 28 August 2017

Original Research

Initial experience of correlating diffusion spectral parameters with histopathologic indexes in murine colorectal tumor homografts

Zhang XY, Li XT, Sun J, Sun YS

OncoTargets and Therapy 2017, 10:4213-4223

Published Date: 26 August 2017

Original Research

HPIP: a predictor of lymph node metastasis and poor survival in cervical cancer

Cao S, Sun J, Lin S, Zhao L, Wu D, Liang T, Sheng W

OncoTargets and Therapy 2017, 10:4205-4211

Published Date: 26 August 2017

Original Research

Investigation of proliferation and migration of tongue squamous cell carcinoma promoted by three chemokines, MIP-3α, MIP-1β, and IP-10

Chu H, Jia B, Qiu X, Pan J, Sun X, Wang Z, Zhao J

OncoTargets and Therapy 2017, 10:4193-4203

Published Date: 29 August 2017

Original Research

Clinical applications of dendritic cells–cytokine-induced killer cells mediated immunotherapy for pancreatic cancer: an up-to-date meta-analysis

Zhang YC, Zhang X, Zhang AQ, Li K, Qu K

OncoTargets and Therapy 2017, 10:4173-4192

Published Date: 23 August 2017

Original Research

miRNA-221 of exosomes originating from bone marrow mesenchymal stem cells promotes oncogenic activity in gastric cancer

Ma M, Chen S, Liu Z, Xie H, Deng H, Shang S, Wang X, Xia M, Zuo C

OncoTargets and Therapy 2017, 10:4161-4171

Published Date: 22 August 2017

Original Research

AKT inhibition is an effective treatment strategy in ARID1A-deficient gastric cancer cells

Lee D, Yu EJ, Ham I, Hur H, Kim Y

OncoTargets and Therapy 2017, 10:4153-4159

Published Date: 22 August 2017

Original Research

RASSF1A hypermethylation is associated with ASXL1 mutation and indicates an adverse outcome in non-M3 acute myeloid leukemia

Liu F, Gong M, Gao L, Cai X, Zhang H, Ma Y

OncoTargets and Therapy 2017, 10:4143-4151

Published Date: 22 August 2017

Original Research

Survival significance of epidermal growth factor receptor tyrosine kinase inhibitors and current staging system for survival after recurrence in patients with completely resected lung adenocarcinoma

Saji H, Sakai H, Kimura H, Miyazawa T, Marushima H, Nakamura H

OncoTargets and Therapy 2017, 10:4135-4141

Published Date: 21 August 2017

Case report

Response to crizotinib in a lung adenocarcinoma patient harboring a novel SLC34A2-ROS1 fusion variant

Zhao Z, Song ZJ, Wang XW, Sun HF, Yang XM, Yuan Y, Yu P

OncoTargets and Therapy 2017, 10:4129-4133

Published Date: 21 August 2017

Original Research

Osteopontin and vasculogenic mimicry formation are associated with response to neoadjuvant chemotherapy in advanced breast cancer

Gu M, Zheng X

OncoTargets and Therapy 2017, 10:4121-4127

Published Date: 18 August 2017

Original Research

Safety and efficacy of nimotuzumab combined with chemoradiotherapy in Chinese patients with locally advanced cervical cancer

Chen Y, Tang W, Pan X, Wu C, Cao Y, Yang W

OncoTargets and Therapy 2017, 10:4113-4119

Published Date: 17 August 2017

Case Series

Clinicopathologic characteristics, therapy and outcomes of patients with primary ureteral small cell carcinoma: a case series and systematic review of the literature

Zhong W, Lin R, Zhang L, Jin C, Li X, He Q, Gong K, He Z, Zhou L

OncoTargets and Therapy 2017, 10:4105-4111

Published Date: 17 August 2017

Case report

Chest reconstruction using a custom-designed polyethylene 3D implant after resection of the sternal manubrium

Lipińska J, Kutwin L, Wawrzycki M, Olbrzymek L, Jabłoński S

OncoTargets and Therapy 2017, 10:4099-4103

Published Date: 17 August 2017

Review

Cabazitaxel in the treatment of metastatic castration-resistant prostate cancer: patient selection and special considerations

Patel SA, Hoffman-Censits J

OncoTargets and Therapy 2017, 10:4089-4098

Published Date: 17 August 2017

Original Research

CT-guided 125I interstitial brachytherapy for pelvic recurrent cervical carcinoma after radiotherapy

Tong L, Liu P, Huo B, Guo Z, Ni H

OncoTargets and Therapy 2017, 10:4081-4088

Published Date: 17 August 2017

Review

Carcinogenicity of chromium and chemoprevention: a brief update

Wang Y, Su H, Gu Y, Song X, Zhao J

OncoTargets and Therapy 2017, 10:4065-4079

Published Date: 16 August 2017

Review

The role of desmosomes in carcinogenesis

Zhou G, Yang L, Gray A, Srivastava AK, Li C, Zhang G, Cui T

OncoTargets and Therapy 2017, 10:4059-4063

Published Date: 14 August 2017

Original Research

Low versus high radioiodine activity for ablation of the thyroid remnant after thyroidectomy in Han Chinese with low-risk differentiated thyroid cancer

Lv RB, Wang QG, Liu C, Liu F, Zhao Q, Han JG, Ren DL, Liu B, Li CL

OncoTargets and Therapy 2017, 10:4051-4057

Published Date: 14 August 2017

Original Research

An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma

Huang CG, Yuan NJ, Wu LY, Wang XF, Dai JQ, Song P, Li FX, Xu CB, Zhao XH

OncoTargets and Therapy 2017, 10:4037-4050

Published Date: 14 August 2017

Original Research

Effect of temozolomide on survival in elderly patients with glioblastoma and impaired performance status: a propensity score–matching analysis

Liu Y, Liu P, Shao W, Du H, Li Z, Guo C, Li Z

OncoTargets and Therapy 2017, 10:4029-4035

Published Date: 14 August 2017

Original Research

Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells

Liu Y, Tang Z, Yang J, Zhou Y, Meng L, Wang H, Li C

OncoTargets and Therapy 2017, 10:4023-4028

Published Date: 11 August 2017

Case report

Perihippocampal metastasis following hippocampus-avoiding prophylactic cranial irradiation for small cell lung cancer: a case report

Yeo SG

OncoTargets and Therapy 2017, 10:4017-4021

Published Date: 11 August 2017

Original Research

Monocyte to lymphocyte ratio predicts survival in patients with advanced gastric cancer undergoing neoadjuvant chemotherapy

Chen L, Hao Y, Zhu LH, Li S, Zuo YJ, Zhang YX, Song HJ, Xue YW

OncoTargets and Therapy 2017, 10:4007-4016

Published Date: 10 August 2017

Original Research

Clinical significance and prospective molecular mechanism of MALAT1 in pancreatic cancer exploration: a comprehensive study based on the GeneChip, GEO, Oncomine, and TCGA databases

Xie ZC, Dang YW, Wei DM, Chen P, Tang RX, Huang Q, Liu JH, Luo DZ

OncoTargets and Therapy 2017, 10:3991-4005

Published Date: 10 August 2017

Original Research

Enhancement of antitumor activity by using a fully human gene encoding a single-chain fragmented antibody specific for carcinoembryonic antigen

Shibaguchi H, Luo N, Shirasu N, Kuroki M, Kuroki M

OncoTargets and Therapy 2017, 10:3979-3990

Published Date: 22 August 2017

Original Research

Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells

Liang J, Gao W, Cai L

OncoTargets and Therapy 2017, 10:3971-3978

Published Date: 7 August 2017

Original Research

Efficacy and safety of apatinib treatment for advanced esophageal squamous cell carcinoma

Li J, Wang L

OncoTargets and Therapy 2017, 10:3965-3969

Published Date: 7 August 2017

Review

Therapies for acute myeloid leukemia: vosaroxin

Sayar H, Bashardoust P

OncoTargets and Therapy 2017, 10:3957-3963

Published Date: 7 August 2017

Original Research

Fibrous sheath interacting protein 1 overexpression is associated with unfavorable prognosis in bladder cancer: a potential therapeutic target

Sun M, Zhao W, Zeng Y, Zhang D, Chen Z, Liu C, Wu B

OncoTargets and Therapy 2017, 10:3949-3956

Published Date: 7 August 2017

Review

NRAS-mutant melanoma: current challenges and future prospect

Muñoz-Couselo E, Zamora Adelantado E, Ortiz C, Soberino García J, Perez-Garcia J

OncoTargets and Therapy 2017, 10:3941-3947

Published Date: 8 August 2017

Review

Bystander signaling via oxidative metabolism

Sawal HA, Asghar K, Bureik M, Jalal N

OncoTargets and Therapy 2017, 10:3925-3940

Published Date: 4 August 2017

Original Research

Prognosis of neutrophil-to-lymphocyte ratio in clinical early-stage tongue (cT1/T2N0) cancer

Wu CN, Chuang HC, Lin YT, Fang FM, Li SH, Chien CY

OncoTargets and Therapy 2017, 10:3917-3924

Published Date: 4 August 2017

Review

Clinicopathological and prognostic significance of circulating tumor cells in patients with head and neck cancer: a meta-analysis

Sun T, Zou K, Yuan Z, Yang C, Lin X, Xiong B

OncoTargets and Therapy 2017, 10:3907-3916

Published Date: 4 August 2017

Original Research

microRNA-130a is an oncomir suppressing the expression of CRMP4 in gastric cancer

Zhou Y, Li R, Yu H, Wang R, Shen Z

OncoTargets and Therapy 2017, 10:3893-3905

Published Date: 3 August 2017

Original Research

SHP2 overexpression enhances the invasion and metastasis of ovarian cancer in vitro and in vivo

Hu ZQ, Li J, Gao Q, Wei S, Yang B

OncoTargets and Therapy 2017, 10:3881-3891

Published Date: 2 August 2017

Review

A practical guide to the handling and administration of talimogene laherparepvec in Europe

Harrington KJ, Michielin O, Malvehy J, Pezzani Grüter I, Grove L, Frauchiger AL, Dummer R

OncoTargets and Therapy 2017, 10:3867-3880

Published Date: 2 August 2017

Original Research

IGF2BP3 as a potential tissue marker for the diagnosis of esophageal high-grade intraepithelial neoplasia

Zhang JJ, Ji Q, Jiao CH, Ren LH, Zhao Y, Chen YF, Shi RH, Feng YD

OncoTargets and Therapy 2017, 10:3861-3866

Published Date: 1 August 2017

Original Research

Outcomes of adding induction chemotherapy to concurrent chemoradiotherapy for stage T3N0-1 nasopharyngeal carcinoma: a propensity-matched study

Lan XW, Xiao Y, Zou XB, Zhang XM, OuYang PY, Xie FY

OncoTargets and Therapy 2017, 10:3853-3860

Published Date: 1 August 2017

Original Research

Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma

Liu W, Hu J, Zhou K, Chen F, Wang Z, Liao B, Dai Z, Cao Y, Fan J, Zhou J

OncoTargets and Therapy 2017, 10:3843-3851

Published Date: 1 August 2017

Original Research

The effect of lipiodol deposition in HCC after TACE on the necrosis range of PMCT

Sun HL, Ni JY, Jiang XY, Chen D, Chen YT, Xu LF

OncoTargets and Therapy 2017, 10:3835-3842

Published Date: 1 August 2017

Original Research

Elevated expression of neuropilin-2 associated with unfavorable prognosis in hepatocellular carcinoma

Dong X, Guo W, Zhang S, Wu T, Sun Z, Yan S, Zheng S

OncoTargets and Therapy 2017, 10:3827-3833

Published Date: 31 July 2017

Original Research

CD155 expression and its correlation with clinicopathologic characteristics, angiogenesis, and prognosis in human cholangiocarcinoma

Huang DW, Huang M, Lin XS, Huang Q

OncoTargets and Therapy 2017, 10:3817-3825

Published Date: 31 July 2017

Original Research

Circulating tumor cells correlate with patterns of recurrence in patients with hormone-sensitive prostate cancer

Roviello G, Corona SP, Bonetta A, Cappelletti MR, Generali D

OncoTargets and Therapy 2017, 10:3811-3815

Published Date: 31 July 2017

Review

The RANK/RANKL/OPG system in tumorigenesis and metastasis of cancer stem cell: potential targets for anticancer therapy

Sisay M, Mengistu G, Edessa D

OncoTargets and Therapy 2017, 10:3801-3810

Published Date: 27 July 2017

Original Research

Preoperative lymphocyte-to-monocyte ratio represents a superior predictor compared with neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios for colorectal liver-only metastases survival

Peng JH, Li H, Ou QJ, Lin JZ, Wu XJ, Lu ZH, Yuan YF, Wan DS, Fang YJ, Pan ZZ

OncoTargets and Therapy 2017, 10:3789-3799

Published Date: 27 July 2017

Original Research

Overexpression of mitochondrial serine hydroxyl-methyltransferase 2 is associated with poor prognosis and promotes cell proliferation and invasion in gliomas

Wu M, Wanggou S, Li X, Liu Q, Xie Y

OncoTargets and Therapy 2017, 10:3781-3788

Published Date: 27 July 2017

Original Research

MDM2 promoter del1518 polymorphism and cancer risk: evidence from 22,931 subjects

Hua WF, Zhang A, Duan P, Zhu J, Zhao Y, He J, Zhang Z

OncoTargets and Therapy 2017, 10:3773-3780

Published Date: 27 July 2017

Review

Volumetric modulated arc therapy for treatment of solid tumors: current insights

Macchia G, Deodato F, Cilla S, Cammelli S, Guido A, Ferioli M, Siepe G, Valentini V, Morganti AG, Ferrandina G

OncoTargets and Therapy 2017, 10:3755-3772

Published Date: 26 July 2017

Original Research

KIAA1522 overexpression promotes tumorigenicity and metastasis of esophageal cancer cells through potentiating the ERK activity

Xie ZH, Yu J, Shang L, Zhu YQ, Hao JJ, Cai Y, Xu X, Zhang Y, Wang MR

OncoTargets and Therapy 2017, 10:3743-3754

Published Date: 26 July 2017

Original Research

Foxj2 overexpression is associated with poor prognosis, progression, and metastasis in nasopharyngeal carcinoma

Shan Y, Chang T, Shi S, Tang M, Bao L, Li L, You B, You Y

OncoTargets and Therapy 2017, 10:3733-3741

Published Date: 24 July 2017

Original Research

Distinct prognostic values of alcohol dehydrogenase mRNA expression in pancreatic adenocarcinoma

Liao X, Huang R, Liu X, Han C, Yu L, Wang SJ, Sun N, Li B, Ning X, Peng T

OncoTargets and Therapy 2017, 10:3719-3732

Published Date: 24 July 2017

Original Research

The prognostic value of decreased miR-101 in various cancers: a meta-analysis of 12 studies

Hu J, Wu C, Zhao X, Liu C

OncoTargets and Therapy 2017, 10:3709-3718

Published Date: 24 July 2017

Review

Emerging role of nivolumab in the management of patients with non-small-cell lung cancer: current data and future perspectives

Feld E, Horn L

OncoTargets and Therapy 2017, 10:3697-3708

Published Date: 24 July 2017

Original Research

miR-203 as a novel biomarker for the diagnosis and prognosis of colorectal cancer: a systematic review and meta-analysis

Ye H, Hao H, Wang J, Chen R, Huang Z

OncoTargets and Therapy 2017, 10:3685-3696

Published Date: 21 July 2017

Original Research

Role of downregulated miR-133a-3p expression in bladder cancer: a bioinformatics study

Gao L, Li SH, Tian YX, Zhu QQ, Chen G, Pang YY, Hu XH

OncoTargets and Therapy 2017, 10:3667-3683

Published Date: 20 July 2017

Review

Clinical targeting recombinant immunotoxins for cancer therapy

Li M, Liu ZS, Liu XL, Hui Q, Lu SY, Qu LL, Li YS, Zhou Y, Ren HL, Hu P

OncoTargets and Therapy 2017, 10:3645-3665

Published Date: 20 July 2017

Original Research

Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia

Guo H, Zhang T, Wen X, Zhou JD, Ma J, An C, Zhang W, Xu Z, Lin J, Qian J

OncoTargets and Therapy 2017, 10:3635-3644

Published Date: 20 July 2017

Original Research

Prognostic and predictive values of PD-L1 expression in patients with digestive system cancer: a meta-analysis

Dai C, Wang M, Lu J, Dai Z, Lin S, Yang P, Tian T, Liu X, Min WL, Dai Z

OncoTargets and Therapy 2017, 10:3625-3634

Published Date: 21 July 2017

Original Research

A systematic comparison of treatment modalities for nasal extranodal natural killer/T-cell lymphoma in early stages between concurrent chemoradiotherapy and sequential chemotherapy

Qian M, Tao HM, Xu W, Ji HZ

OncoTargets and Therapy 2017, 10:3617-3623

Published Date: 20 July 2017

Original Research

Impact of combined treatment with nimesulide and cisplatin on oral carcinoma cells

Barac A, Mitulovic G, Hallström S, Zehetmayer S, Grasl MC, Erovic BM

OncoTargets and Therapy 2017, 10:3607-3616

Published Date: 19 July 2017

Original Research

Identification of the anticancer effects of a novel proteasome inhibitor, ixazomib, on colorectal cancer using a combined method of microarray and bioinformatics analysis

Fan QW, Liu BR

OncoTargets and Therapy 2017, 10:3591-3606

Published Date: 19 July 2017

Original Research

Emodin suppresses proliferation, migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo

Lu JJ, Xu Y, Zhao Z, Ke XN, Wei X, Kang J, Zong X, Mao HL, Liu PS

OncoTargets and Therapy 2017, 10:3579-3589

Published Date: 19 July 2017

Review

Immunotargeting relapsed or refractory precursor B-cell acute lymphoblastic leukemia – role of blinatumomab

Queudeville M, Handgretinger R, Ebinger M

OncoTargets and Therapy 2017, 10:3567-3578

Published Date: 19 July 2017

Original Research

The status of immunosuppression in patients with stage IIIB or IV non-small-cell lung cancer correlates with the clinical characteristics and response to chemotherapy

Wang Y, Hu GF, Wang ZH

OncoTargets and Therapy 2017, 10:3557-3566

Published Date: 19 July 2017

Original Research

Combined detection of dickkopf-1 subtype classification autoantibodies as biomarkers for the diagnosis and prognosis of non-small cell lung cancer

Shen L, Wu X, Tan J, Gu M, Teng Y, Wang Z, Yue W

OncoTargets and Therapy 2017, 10:3545-3556

Published Date: 18 July 2017

Original Research

Targeted TPX2 increases chromosome missegregation and suppresses tumor cell growth in human prostate cancer

Pan HW, Su HH, Hsu C, Huang GJ, Wu TT

OncoTargets and Therapy 2017, 10:3531-3543

Published Date: 17 July 2017

Original Research

Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells

Li J, Zhen L, Zhang Y, Zhao L, Liu H, Cai D, Chen H, Yu J, Qi X, Li G

OncoTargets and Therapy 2017, 10:3521-3529

Published Date: 17 July 2017

Original Research

Analysis of clinical characteristics and efficacy of chronic myeloid leukemia onset with extreme thrombocytosis in the era of tyrosine kinase inhibitors

Liu Z, Fan H, Li Y, Liu C

OncoTargets and Therapy 2017, 10:3515-3520

Published Date: 17 July 2017

Original Research

Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer

Heerma van Voss MR, Vesuna F, Bol GM, Meeldijk J, Raman A, Offerhaus GJ, Buerger H, Patel AH, van der Wall E, van Diest PJ, Raman V

OncoTargets and Therapy 2017, 10:3501-3513

Published Date: 17 July 2017

Original Research

An evaluation of the clinical diagnostic value of contrast-enhanced ultrasound combined with contrast-enhanced computed tomography in space-occupying lesions of the kidney

Tian W, Lu JB, Jiao D, Cong ZB

OncoTargets and Therapy 2017, 10:3493-3499

Published Date: 14 July 2017

Original Research

Interleukin-35 as a predictor of prostate cancer in patients undergoing initial prostate biopsy

Zhou CC, Zhang J, Chen Y, Wang H, Hou JQ

OncoTargets and Therapy 2017, 10:3485-3491

Published Date: 14 July 2017

Original Research

Association between polymorphisms in DNA repair gene XRCC1 and non-melanoma skin cancer risk: a meta-analysis

Wang L, Xu J, Duan B

OncoTargets and Therapy 2017, 10:3475-3483

Published Date: 13 July 2017

Original Research

Ergosterol peroxide inhibits ovarian cancer cell growth through multiple pathways

Tan W, Pan M, Liu H, Tian H, Ye Q, Liu H

OncoTargets and Therapy 2017, 10:3467-3474

Published Date: 13 July 2017

Original Research

PD-1 blockade restores impaired function of ex vivo expanded CD8+ T cells and enhances apoptosis in mismatch repair deficient EpCAM+PD-L1+ cancer cells

Kumar R, Yu F, Zhen YH, Li B, Wang J, Yang Y, Ge HX, Hu P, Xiu J

OncoTargets and Therapy 2017, 10:3453-3465

Published Date: 13 July 2017

Review

Recent progress on the effects of microRNAs and natural products on tumor epithelial–mesenchymal transition

He SJ, Xiang CQ, Zhang Y, Lu XT, Chen HW, Xiong LX

OncoTargets and Therapy 2017, 10:3435-3451

Published Date: 12 July 2017

Original Research

Evaluation of p53 gene expression and prognosis characteristics in uveal melanoma cases

Liu H, Zhou M

OncoTargets and Therapy 2017, 10:3429-3434

Published Date: 12 July 2017

Original Research

RNA sequencing identifies gene expression profile changes associated with β-estradiol treatment in U2OS osteosarcoma cells

Chen B, Liu Z, Zhang J, Wang H, Yu B

OncoTargets and Therapy 2017, 10:3421-3427

Published Date: 11 July 2017

Original Research

A comprehensive insight into the clinicopathologic significance of miR-144-3p in hepatocellular carcinoma

Liang HW, Ye ZH, Yin SY, Mo WJ, Wang HL, Zhao JC, Liang GM, Feng ZB, Chen G, Luo DZ

OncoTargets and Therapy 2017, 10:3405-3419

Published Date: 11 July 2017

Original Research

ALK and ROS1 concurrent with EGFR mutation in patients with lung adenocarcinoma

Mao Y, Wu S

OncoTargets and Therapy 2017, 10:3399-3404

Published Date: 11 July 2017

Review

Prognostic role of lymphocyte to monocyte ratio for patients with pancreatic cancer: a systematic review and meta-analysis

Li W, Tao L, Zhang L, Xiu D

OncoTargets and Therapy 2017, 10:3391-3397

Published Date: 11 July 2017

Original Research

Sex-related differences in clinicopathological features and survival of patients with primary urethral carcinoma: a population-based study

Wei Y, Wu YP, Xu N, Li XD, Chen SH, Cai H, Zheng QS, Xue XY

OncoTargets and Therapy 2017, 10:3381-3389

Published Date: 10 July 2017

Original Research

The translational expression of ABCA2 and ABCA3 is a strong prognostic biomarker for multidrug resistance in pediatric acute lymphoblastic leukemia

Aberuyi N, Rahgozar S, Khosravi Dehaghi Z, Moafi A, Masotti A, Paolini A

OncoTargets and Therapy 2017, 10:3373-3380

Published Date: 10 July 2017

Review

Emerging treatments for HER2-positive early-stage breast cancer: focus on neratinib

Kourie HR, El Rassy E, Clatot F, de Azambuja E, Lambertini M

OncoTargets and Therapy 2017, 10:3363-3372

Published Date: 10 July 2017

Original Research

The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer

Chen ZL, Liu H, Yang HL, Gao YK, Zhang GW, Hu JJ

OncoTargets and Therapy 2017, 10:3353-3362

Published Date: 10 July 2017

Original Research

Preoperative serum carcinoembryonic antigen levels are associated with histologic subtype, EGFR mutations, and ALK fusion in patients with completely resected lung adenocarcinoma

Wang Z, Yang S, Lu H

OncoTargets and Therapy 2017, 10:3345-3351

Published Date: 7 July 2017

Original Research

Polypeptide N-acetylgalactosaminyltransferase-6 expression in gastric cancer

Guo Y, Shi JJ, Zhang J, Li HX, Liu B, Guo H

OncoTargets and Therapy 2017, 10:3337-3344

Published Date: 7 July 2017

Original Research

Induction chemotherapy followed by intensity-modulated radiotherapy with reduced gross tumor volume delineation for stage T3-4 nasopharyngeal carcinoma

Xue F, Hu C, He X

OncoTargets and Therapy 2017, 10:3329-3336

Published Date: 6 July 2017

Original Research

Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells

Woitok M, Klose D, Di Fiore S, Richter W, Stein C, Gresch G, Grieger E, Barth S, Fischer R, Kolberg K, Niesen J

OncoTargets and Therapy 2017, 10:3313-3327

Published Date: 6 July 2017

Original Research

Conventional real-time PCR-based detection of T790M using tumor tissue or blood in patients with EGFR TKI-resistant NSCLC

Wu Y, Tong R, Zhang Y, Hu B, Zheng K, Ding Z, Peng F, Gong Y, Liu Y, Lu Y

OncoTargets and Therapy 2017, 10:3307-3312

Published Date: 5 July 2017

Review

Novel agents for the treatment of childhood leukemia: an update

Eryılmaz E, Canpolat C

OncoTargets and Therapy 2017, 10:3299-3306

Published Date: 4 July 2017

Original Research

Reactive oxygen species mediate soft corals-derived sinuleptolide-induced antiproliferation and DNA damage in oral cancer cells

Chang YT, Huang C, Tang J, Liaw C, Li R, Liu J, Sheu J, Chang HW

OncoTargets and Therapy 2017, 10:3289-3297

Published Date: 4 July 2017

Case report

Primary lung sarcoma treated with stereotactic ablative radiotherapy: a case report

Yeo SG

OncoTargets and Therapy 2017, 10:3285-3288

Published Date: 4 July 2017

Original Research

Therapeutic value of 3-D printing template-assisted 125I-seed implantation in the treatment of malignant liver tumors

Han T, Yang X, Xu Y, Zheng Z, Yan Y, Wang N

OncoTargets and Therapy 2017, 10:3277-3283

Published Date: 3 July 2017

Review

The diagnostic and prognostic values of Ki-67/MIB-1 expression in thyroid cancer: a meta-analysis with 6,051 cases

Pan DH, Wen DY, Luo YH, Chen G, Yang H, Chen JQ, He Y

OncoTargets and Therapy 2017, 10:3261-3276

Published Date: 3 July 2017

Review

Hedgehog signaling pathway in colorectal cancer: function, mechanism, and therapy

Wu C, Zhu X, Liu W, Ruan T, Tao K

OncoTargets and Therapy 2017, 10:3249-3259

Published Date: 30 June 2017

Original Research

LincRNA-p21 inhibits invasion and metastasis of hepatocellular carcinoma through miR-9/E-cadherin cascade signaling pathway molecular mechanism

Ding G, Peng Z, Shang J, Kang Y, Ning HB, Mao CS

OncoTargets and Therapy 2017, 10:3241-3247

Published Date: 30 June 2017

Original Research

Targeted regulation of MiR-98 on E2F1 increases chemosensitivity of leukemia cells K562/A02

Huang YD, Hong XL, Hu J, Lu Q

OncoTargets and Therapy 2017, 10:3233-3239

Published Date: 29 June 2017

Original Research

Exploration of the molecular mechanism of prostate cancer based on mRNA and miRNA expression profiles

Zhang X, Sun YY, Wang P, Yang CF, Li SW

OncoTargets and Therapy 2017, 10:3225-3232

Published Date: 29 June 2017

Original Research

CXCL12 suppresses cisplatin-induced apoptosis through activation of JAK2/STAT3 signaling in human non-small-cell lung cancer cells

Wang M, Lin T, Wang YC, Gao S, Yang ZY, Hong X, Chen GY

OncoTargets and Therapy 2017, 10:3215-3224

Published Date: 29 June 2017

Case report

Adverse renal effects of anaplastic lymphoma kinase inhibitors and the response to alectinib of an ALK+ lung cancer patient with renal dysfunction

Shimada M, Fukuda M, Fukuda M, Kitazaki T, Hashiguchi K, Ikeda T, Yamaguchi H, Nakatomi K, Ashizawa K, Mukae H

OncoTargets and Therapy 2017, 10:3211-3214

Published Date: 29 June 2017

Original Research

Association of estrogen receptor α PvuII and XbaI polymorphisms with prostate cancer susceptibility and risk stratification: a meta-analysis from case-control studies

Zhao YN, Zheng X, Zhang LJ, Hu Q, Guo YT, Jiang H, Shi SN, Zhang X

OncoTargets and Therapy 2017, 10:3203-3210

Published Date: 29 June 2017

Original Research

The effect of circulating miR-223 on surveillance of different cancers: a meta-analysis

Zhang YF, Lin JB, Huang WJ, Cao Y, Liu Y, Wang TQ, Zhong WY, Wang DL, Mao RR, Chen XL

OncoTargets and Therapy 2017, 10:3193-3201

Published Date: 28 June 2017

Case report

Patients harboring ALK rearrangement adenocarcinoma after acquired resistance to crizotinib and transformation to small-cell lung cancer: a case report

Zhu Y, Liao X, Wang W, Xu C, Zhuang W, Zhong L, Du K, Chen Y, Chen G, Fang M

OncoTargets and Therapy 2017, 10:3187-3192

Published Date: 27 June 2017

Original Research

Phase I dose-escalation study of long-acting pasireotide in patients with neuroendocrine tumors

Yao JC, Chan JA, Mita AC, Kundu MG, Hermosillo Reséndiz K, Hu K, Ravichandran S, Strosberg JR, Wolin EM

OncoTargets and Therapy 2017, 10:3177-3186

Published Date: 27 June 2017

Original Research

Clinical importance of serum HE4 and MMP2 levels in endometrial cancer patients

Cymbaluk-Ploska A, Chudecka-Głaz A, Pius-Sadowska E, Sompolska-Rzechuła A, Machaliński B, Surowiec A, Menkiszak J

OncoTargets and Therapy 2017, 10:3169-3175

Published Date: 27 June 2017

Original Research

Optimizing the treatment of bevacizumab as first-line therapy for human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer: an updated meta-analysis of published randomized trials

Li C, Xiang A, Chen X, Yin K, Lu J, Yin W

OncoTargets and Therapy 2017, 10:3155-3168

Published Date: 27 June 2017

Original Research

Derived neutrophil to lymphocyte ratio and monocyte to lymphocyte ratio may be better biomarkers for predicting overall survival of patients with advanced gastric cancer

Song S, Li C, Li S, Gao H, Lan X, Xue Y

OncoTargets and Therapy 2017, 10:3145-3154

Published Date: 26 June 2017

Original Research

Histone demethylase KDM2B upregulates histone methyltransferase EZH2 expression and contributes to the progression of ovarian cancer in vitro and in vivo

Kuang Y, Lu F, Guo J, Xu H, Wang Q, Xu C, Zeng L, Yi S

OncoTargets and Therapy 2017, 10:3131-3144

Published Date: 26 June 2017

Original Research

The association between SPINK1 and clinical outcomes in patients with prostate cancer: a systematic review and meta-analysis

Zhang X, Yin X, Shen P, Sun G, Yang Y, Liu J, Chen N, Zeng H

OncoTargets and Therapy 2017, 10:3123-3130

Published Date: 22 June 2017

Review

Clinical efficacy evaluation of tyrosine kinase inhibitors for non-adenocarcinoma lung cancer patients harboring EGFR-sensitizing mutations

Song X, Wang Z

OncoTargets and Therapy 2017, 10:3119-3122

Published Date: 22 June 2017

Original Research

Plasma fibrinogen and serum albumin levels (FA score) act as a promising prognostic indicator in non-small cell lung cancer

Chen P, Wang C, Cheng B, Nesa EU, Liu Y, Jia Y, Qu Y, Jiang Z, Han J, Cheng Y

OncoTargets and Therapy 2017, 10:3107-3118

Published Date: 21 June 2017

Original Research

Comprehensive analysis of differential co-expression patterns reveal transcriptional dysregulation mechanism and identify novel prognostic lncRNAs in esophageal squamous cell carcinoma

Li Z, Yao Q, Zhao S, Wang Y, Li Y, Wang Z

OncoTargets and Therapy 2017, 10:3095-3105

Published Date: 21 June 2017

Original Research

Association of FHIT expression and FHIT gene hypermethylation with liver cancer risk: a PRISMA-compliant meta-analysis

Zhang Y, Xu X, Chen Z, Zhao Z

OncoTargets and Therapy 2017, 10:3083-3093

Published Date: 20 June 2017

Original Research

Relationship between UGT1A16/28 gene polymorphisms and the efficacy and toxicity of irinotecan-based chemotherapy

Bai Y, Wu HW, Ma X, Liu Y, Zhang YH

OncoTargets and Therapy 2017, 10:3071-3081

Published Date: 19 June 2017

Review

The prognostic value of C-reactive protein/albumin ratio in human malignancies: an updated meta-analysis

Xu H, Ma Y, Deng F, Ju W, Sun X, Wang H

OncoTargets and Therapy 2017, 10:3059-3070

Published Date: 19 June 2017

Original Research

Isolated thoracic perfusion with chemofiltration for progressive malignant pleural mesothelioma

Aigner KR, Selak E, Gailhofer S

OncoTargets and Therapy 2017, 10:3049-3057

Published Date: 19 June 2017

Original Research

Downregulation of lncRNA SDPR-AS is associated with poor prognosis in renal cell carcinoma

Ni W, Song E, Gong M, Li Y, Yao J, An R

OncoTargets and Therapy 2017, 10:3039-3047

Published Date: 19 June 2017

Review

Rucaparib: the past, present, and future of a newly approved PARP inhibitor for ovarian cancer

Dockery LE, Gunderson CC, Moore KN

OncoTargets and Therapy 2017, 10:3029-3037

Published Date: 19 June 2017

Original Research

Identification of key genes and molecular mechanisms associated with dedifferentiated liposarcoma based on bioinformatic methods

Yu H, Pei D, Chen L, Zhou X, Zhu H

OncoTargets and Therapy 2017, 10:3017-3027

Published Date: 16 June 2017

Original Research

Skin toxicity evaluation in patients treated with cetuximab for metastatic colorectal cancer: a new tool for more accurate comprehension of quality of life impacts

De Tursi M, Zilli M, Carella C, Auriemma M, Lisco MN, Di Nicola M, Di Martino G, Natoli C, Amerio P

OncoTargets and Therapy 2017, 10:3007-3015

Published Date: 16 June 2017

Original Research

Hepatic artery-infusion chemotherapy improved survival of hepatocellular carcinoma after radical hepatectomy

Feng M, Tang C, Feng W, Bao Y, Zheng Y, Shen J

OncoTargets and Therapy 2017, 10:3001-3005

Published Date: 14 June 2017

Original Research

Combination of azacitidine and trichostatin A decreased the tumorigenic potential of lung cancer cells

Yang Y, Yin W, Wu FY, Fan J

OncoTargets and Therapy 2017, 10:2993-2999

Published Date: 14 June 2017

Original Research

Overexpression of PD-L2 is associated with shorter relapse-free survival in patients with malignant salivary gland tumors

Chang H, Kim JS, Choi YJ, Cho J, Woo J, Kim A, Kim JS, Kang EJ

OncoTargets and Therapy 2017, 10:2983-2992

Published Date: 13 June 2017

Original Research

Accelerated or hyperfractionated radiotherapy for esophageal carcinoma: a meta-analysis of randomized controlled trials

Liu YY, Kou CG, Su YY, Zhang YY, You YY, Zhang LL, Wang MH, Fu YL, Ren XJ, Yang YM

OncoTargets and Therapy 2017, 10:2971-2981

Published Date: 13 June 2017

Original Research

Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult Ewing sarcoma patients treated with chemotherapy

de Groot S, Gelderblom H, Fiocco M, Bovée JVMG, van der Hoeven JJM, Pijl H, Kroep JR

OncoTargets and Therapy 2017, 10:2963-2970

Published Date: 13 June 2017

Original Research

Overexpression of the cancer stem cell marker CD117 predicts poor prognosis in epithelial ovarian cancer patients: evidence from meta-analysis

Yang B, Yan X, Liu L, Jiang C, Hou S

OncoTargets and Therapy 2017, 10:2951-2961

Published Date: 13 June 2017

Original Research

Prognosis of prostate cancer with initial prostate-specific antigen >1,000 ng/mL at diagnosis

Kan HC, Hou CP, Lin YH, Tsui KH, Chang PL, Chen CL

OncoTargets and Therapy 2017, 10:2943-2949

Published Date: 12 June 2017

Original Research

WWC3 downregulation correlates with poor prognosis and inhibition of Hippo signaling in human gastric cancer

Hou J, Zhou J

OncoTargets and Therapy 2017, 10:2931-2942

Published Date: 12 June 2017

Original Research

Vasculogenic mimicry is associated with increased tumor-infiltrating neutrophil and poor outcome in esophageal squamous cell carcinoma

Zhang J, Zhang G, Hu P, Deng G, Liu Q, Qiao L, Luo H, Zhang J

OncoTargets and Therapy 2017, 10:2923-2930

Published Date: 9 June 2017

Original Research

Long-term outcomes of neoadjuvant chemotherapy followed by concurrent chemoradiotherapy (CCRT) vs CCRT alone for nasopharyngeal carcinoma in the era of intensity-modulated radiation therapy using propensity score matching method

Chen X, Zhu X, Liang Z, Li L, Qu S, Chen K, Pan X

OncoTargets and Therapy 2017, 10:2909-2921

Published Date: 9 June 2017

Original Research

Epidermal growth factor receptor exon 20 mutation in lung cancer: types, incidence, clinical features and impact on treatment

Noronha V, Choughule A, Patil VM, Joshi A, Kumar R, Susan Joy Philip D, Banavali S, Dutt A, Prabhash K

OncoTargets and Therapy 2017, 10:2903-2908

Published Date: 9 June 2017

Review

The prognostic value of cyclooxygenase-2 expression in patients with esophageal cancer: evidence from a meta-analysis

Hu Z, Yang Y, Zhao Y, Huang Y

OncoTargets and Therapy 2017, 10:2893-2901

Published Date: 9 June 2017

Original Research

Stereotactic body radiotherapy or stereotactic ablative radiotherapy versus surgery for patients with T1-3N0M0 non-small cell lung cancer: a systematic review and meta-analysis

Li M, Yang X, Chen Y, Yang X, Dai X, Sun F, Zhang L, Zhan C, Feng M, Wang Q

OncoTargets and Therapy 2017, 10:2885-2892

Published Date: 7 June 2017

Original Research

Upregulated long noncoding RNA PANDAR predicts an unfavorable prognosis and promotes tumorigenesis in cholangiocarcinoma

Xu Y, Jiang X, Cui Y

OncoTargets and Therapy 2017, 10:2873-2883

Published Date: 6 June 2017

Original Research

PI3K/AKT/mTOR pathway promotes progestin resistance in endometrial cancer cells by inhibition of autophagy

Liu H, Zhang L, Zhang X, Cui Z

OncoTargets and Therapy 2017, 10:2865-2871

Published Date: 6 June 2017

Original Research

Prognostic value of high IMP3 expression in solid tumors: a meta-analysis

Chen L, Xie Y, Li X, Gu L, Gao Y, Tang L, Chen J, Zhang X

OncoTargets and Therapy 2017, 10:2849-2863

Published Date: 6 June 2017

Original Research

Role of matrix metalloproteinase-9 in transforming growth factor-β1-induced epithelial–mesenchymal transition in esophageal squamous cell carcinoma

Bai X, Li Y, Zhang H, Wang F, He H, Yao J, Liu L, Li S

OncoTargets and Therapy 2017, 10:2837-2847

Published Date: 2 June 2017

Retraction

Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells [Retraction]

Yu L, Wang XL, Zhu D, Ding W, Wang L, Zhang C, Jiang X, Shen H, Liao S, Ma D, Hu Z, Wang H

OncoTargets and Therapy 2017, 10:2835-2836

Published Date: 2 June 2017

Original Research

SUN1 silencing inhibits cell growth through G0/G1 phase arrest in lung adenocarcinoma

Huang W, Huang H, Wang L, Hu J, Song W

OncoTargets and Therapy 2017, 10:2825-2833

Published Date: 2 June 2017

Letter

Letter to the editor regarding the article “Prognostic role of long noncoding RNA NEAT1 in various carcinomas: a meta-analysis”

Yu H, Wang P, Zhang X

OncoTargets and Therapy 2017, 10:2823-2824

Published Date: 6 June 2017

Original Research

MicroRNA-148b suppresses proliferation, migration, and invasion of nasopharyngeal carcinoma cells by targeting metastasis-associated gene 2

Wu MH, Ye XX, Wang SC, Li QH, Lai YX, Yi YM

OncoTargets and Therapy 2017, 10:2815-2822

Published Date: 2 June 2017

Original Research

Panel of seven long noncoding RNA as a candidate prognostic biomarker for ovarian cancer

Zhan XH, Dong C, Liu G, Li YX, Liu L

OncoTargets and Therapy 2017, 10:2805-2813

Published Date: 1 June 2017

Original Research

Silencing of AQP3 induces apoptosis of gastric cancer cells via downregulation of glycerol intake and downstream inhibition of lipogenesis and autophagy

Chen L, Li Z, Zhang Q, Wei S, Li B, Zhang X, Zhang L, Li Q, Xu H, Xu Z

OncoTargets and Therapy 2017, 10:2791-2804

Published Date: 1 June 2017

Original Research

The critical role of EGF-β-catenin signaling in the epithelial-mesenchymal transition in human glioblastoma

Wang X, Wang S, Li X, Jin S, Xiong F, Wang X

OncoTargets and Therapy 2017, 10:2781-2789

Published Date: 31 May 2017

Corrigendum

Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells [Corrigendum]

Ye T, Su J, Huang C, Yu D, Dai S, Huang X, Chen B, Zhou M

OncoTargets and Therapy 2017, 10:2779-2780

Published Date: 31 May 2017

Original Research

The role of long noncoding RNA-LET in cell proliferation and invasion of nasopharyngeal carcinoma and its mechanism

Chen L, Sun L, Dong L, Cui P, Xia Z, Li C, Zhu Y

OncoTargets and Therapy 2017, 10:2769-2778

Published Date: 30 May 2017

Original Research

Efficacy and safety of TACE in combination with sorafenib for the treatment of TACE-refractory advanced hepatocellular carcinoma in Chinese patients: a retrospective study

Wu J, Li A, Yang J, Lu Y, Li J

OncoTargets and Therapy 2017, 10:2761-2768

Published Date: 29 May 2017

Original Research

Pretreatment combination of platelet counts and neutrophil–lymphocyte ratio predicts survival of nasopharyngeal cancer patients receiving intensity-modulated radiotherapy

Lin YH, Chang KP, Lin YS, Chang TS

OncoTargets and Therapy 2017, 10:2751-2760

Published Date: 26 May 2017

Original Research

Neoadjuvant chemotherapy combined with limb salvage surgery in patients with limb osteosarcoma of Enneking stage II: a retrospective study

Yuan G, Chen J, Wu D, Gao C

OncoTargets and Therapy 2017, 10:2745-2750

Published Date: 26 May 2017

Original Research

Overexpression of ecotropic viral integration site-1 is a prognostic factor of lung squamous cell cancer

Xu X, Liu S, Ji X

OncoTargets and Therapy 2017, 10:2739-2744

Published Date: 26 May 2017

Corrigendum

Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis [Corrigendum]

Xia S, Wang C, Postma EL, Yang Y, Ni X, Zhan W

OncoTargets and Therapy 2017, 10:2737-2738

Published Date: 29 May 2017

Original Research

The prognostic value of nodal skip metastasis in resectable thoracic esophageal squamous cell carcinoma

Song G, Jing W, Xue S, Guo H, Yu J

OncoTargets and Therapy 2017, 10:2729-2736

Published Date: 25 May 2017

Original Research

Leucine-rich glioma inactivated 3: integrative analyses support its prognostic role in glioma

Kwon NS, Kim DS, Yun HY

OncoTargets and Therapy 2017, 10:2721-2728

Published Date: 24 May 2017

Original Research

miR-124 suppresses proliferation and invasion of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway by targeting Capn4

Hu H, Wang G, Li C

OncoTargets and Therapy 2017, 10:2711-2720

Published Date: 23 May 2017

Original Research

MicroRNA-216a promotes the metastasis and epithelial–mesenchymal transition of ovarian cancer by suppressing the PTEN/AKT pathway

Liu H, Pan Y, Han X, Liu J, Li R

OncoTargets and Therapy 2017, 10:2701-2709

Published Date: 23 May 2017

Original Research

Effects of chemopreventive agents on the incidence of recurrent colorectal adenomas: a systematic review with network meta-analysis of randomized controlled trials

Veettil SK, Teerawattanapong N, Ching SM, Lim KG, Saokaew S, Phisalprapa P, Chaiyakunapruk N

OncoTargets and Therapy 2017, 10:2689-2700

Published Date: 23 May 2017

Editorial

Ezh2, a novel target in detection and therapy of breast cancer

Pourakbar S, Pluard TJ, Accurso AD, Farassati F

OncoTargets and Therapy 2017, 10:2685-2687

Published Date: 22 May 2017

Original Research

Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancer

Shao Y, Zhu W, Da J, Xu M, Wang Y, Zhou J, Wang Z

OncoTargets and Therapy 2017, 10:2675-2683

Published Date: 22 May 2017

Original Research

Expression of urinary miRNAs targeting NLRs inflammasomes in bladder cancer

Mearini E, Poli G, Cochetti G, Boni A, Egidi MG, Brancorsini S

OncoTargets and Therapy 2017, 10:2665-2673

Published Date: 22 May 2017

Original Research

The prognostic value of neutrophil–lymphocyte ratio is superior to derived neutrophil–lymphocyte ratio in advanced gastric cancer treated with preoperative chemotherapy and sequential R0 resection: a 5-year follow-up

Jin H, Sun J, Zhu K, Liu X, Zhang Q, Shen Q, Gao Y, Yu J

OncoTargets and Therapy 2017, 10:2655-2664

Published Date: 22 May 2017

Original Research

Association between clinicopathological features and survival in patients with primary and paired metastatic colorectal cancer and KRAS mutation

Pang X, Li Q, Ma Z, Shi Y, Ma Y, Li X, Cui W, Zhang W

OncoTargets and Therapy 2017, 10:2645-2654

Published Date: 19 May 2017

Original Research

The novel long noncoding RNA RP11–357H14.17 acts as an oncogene by promoting cell proliferation and invasion in diffuse-type gastric cancer

Yang B, Luo TH, Zhang MJ, Lu ZM, Xue XC, Fang GN

OncoTargets and Therapy 2017, 10:2635-2643

Published Date: 18 May 2017

Original Research

FOLFOX regimen plus dendritic cells–cytokine-induced killer cells immunotherapy for the treatment of colorectal cancer: a meta-analysis

Liu Y, Zheng Z, Zhang QX, Zhou XL, Feng YK, Yan AQ

OncoTargets and Therapy 2017, 10:2621-2633

Published Date: 18 May 2017

Original Research

RNA-binding protein HuR promotes bladder cancer progression by competitively binding to the long noncoding HOTAIR with miR-1

Yu DP, Zhang C, Gui JQ

OncoTargets and Therapy 2017, 10:2609-2619

Published Date: 17 May 2017

Original Research

Holliday junction–recognizing protein promotes cell proliferation and correlates with unfavorable clinical outcome of hepatocellular carcinoma

Hu B, Wang Q, Wang Y, Chen J, Li P, Han M

OncoTargets and Therapy 2017, 10:2601-2607

Published Date: 17 May 2017

Original Research

Efficacy and safety of pemetrexed on recurrent primary central nervous system lymphomas in China: a prospective study

Sun Y, Wang Y, Han S, Xing B, Li H, Zhu Y, Zhou S, Wang X, Xu J, Tao R

OncoTargets and Therapy 2017, 10:2595-2600

Published Date: 17 May 2017

Original Research

The HIV protease inhibitor, nelfinavir, as a novel therapeutic approach for the treatment of refractory pediatric leukemia

Meier-Stephenson V, Riemer J, Narendran A

OncoTargets and Therapy 2017, 10:2581-2593

Published Date: 16 May 2017

Original Research

Peripheral venous blood neutrophil-to-lymphocyte ratio predicts survival in patients with advanced gastric cancer treated with neoadjuvant chemotherapy

Chen L, Zuo YJ, Zhu LH, Zhang YX, Li S, Ma F, Han Y, Song HJ, Xue YW

OncoTargets and Therapy 2017, 10:2569-2580

Published Date: 17 May 2017

Original Research

Analysis of immune status after iodine-125 permanent brachytherapy in prostate cancer

Du E, Wang L, Li C, Zhang C, Qu Y, Liu R, Xu Y, Yang K, Zhang Z

OncoTargets and Therapy 2017, 10:2561-2567

Published Date: 15 May 2017

Original Research

Predictive significance of HMGCS2 for prognosis in resected Chinese esophageal squamous cell carcinoma patients

Tang H, Wu Y, Qin Y, Wang H, Jia Y, Yang S, Luo S, Wang Q

OncoTargets and Therapy 2017, 10:2553-2560

Published Date: 15 May 2017

Review

Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer

Hollis RL, Churchman M, Gourley C

OncoTargets and Therapy 2017, 10:2539-2551

Published Date: 11 May 2017

Original Research

MicroRNA-381 enhances radiosensitivity in esophageal squamous cell carcinoma by targeting X-linked inhibitor of apoptosis protein

Zhou S, Cui Y, Yu D, Liang J, Zhang M, Ye W

OncoTargets and Therapy 2017, 10:2527-2538

Published Date: 11 May 2017

Review

New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

Hirsh V

OncoTargets and Therapy 2017, 10:2513-2526

Published Date: 11 May 2017

Corrigendum

Retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia: current perspectives [Corrigendum]

McCulloch D, Brown C, Iland H

OncoTargets and Therapy 2017, 10:2511-2512

Published Date: 8 May 2017

Original Research

Aberrant promoter methylation profiles and association with survival in patients with hepatocellular carcinoma

Zhong D, Cen H

OncoTargets and Therapy 2017, 10:2501-2509

Published Date: 8 May 2017

Original Research

Clinicopathological significance of p14ARF expression in lung cancer: a meta-analysis

Wang F, Li H, Long J, Ye S

OncoTargets and Therapy 2017, 10:2491-2499

Published Date: 8 May 2017

Review

Ocular basal cell carcinoma: a brief literature review of clinical diagnosis and treatment

Shi Y, Jia R, Fan X

OncoTargets and Therapy 2017, 10:2483-2489

Published Date: 8 May 2017

Original Research

Tyrosine kinase inhibitor combination therapy in first-line treatment of non-small-cell lung cancer: systematic review and network meta-analysis

Batson S, Mitchell SA, Windisch R, Damonte E, Munk VC, Reguart N

OncoTargets and Therapy 2017, 10:2473-2482

Published Date: 5 May 2017

Original Research

Downregulation of long noncoding RNA TUG1 inhibits proliferation and induces apoptosis through the TUG1/miR-142/ZEB2 axis in bladder cancer cells

Liu Q, Liu H, Cheng HP, Li Y, Li XD, Zhu CY

OncoTargets and Therapy 2017, 10:2461-2471

Published Date: 5 May 2017

Original Research

A retrospective study on the prognostic value of preoperative neutrophil/lymphocyte ratio in patients with primary small-cell carcinoma of the esophagus

Wang Y, Liu JF

OncoTargets and Therapy 2017, 10:2453-2459

Published Date: 5 May 2017

Case report

An isolated unusual digit metastasis from esophageal carcinoma: a case report

Chen Y, Tang W, Xiao H, Chen J, Zhao H, Shi J

OncoTargets and Therapy 2017, 10:2449-2452

Published Date: 9 May 2017

Original Research

Sialylation facilitates self-assembly of 3D multicellular prostaspheres by using cyclo-RGDfK(TPP) peptide

Haq S, Samuel V, Haxho F, Akasov R, Leko M, Burov SV, Markvicheva E, Szewczuk MR

OncoTargets and Therapy 2017, 10:2427-2447

Published Date: 4 May 2017

Retraction

The coexpression of EphB4 and EphrinB2 is associated with poor prognosis in HER2-positive breast cancer [Retraction]

Li X, Song C, Huang G, Sun S, Qiao J, Zhao J, Zhao Z, Li M

OncoTargets and Therapy 2017, 10:2425-2426

Published Date: 4 May 2017

Original Research

Characteristics of circulating tumor cells in organ metastases, prognosis, and T lymphocyte mediated immune response

Sun WW, Xu ZH, Lian P, Gao BL, Hu JA

OncoTargets and Therapy 2017, 10:2413-2424

Published Date: 4 May 2017

Retraction

FAM172A expression in circulating tumor cells for prediction of high-risk subgroups of colorectal cancer [Retraction]

Xu C, Zhang C, Wang H, Yang H, Li G, Fei Z, Li W

OncoTargets and Therapy 2017, 10:2411-2412

Published Date: 3 May 2017

Original Research

The voice quality after laser surgery versus radiotherapy of T1a glottic carcinoma: systematic review and meta-analysis

Huang GJ, Luo MS, Zhang JX, Liu HB

OncoTargets and Therapy 2017, 10:2403-2410

Published Date: 3 May 2017

Original Research

Immunogenicity of oncolytic vaccinia viruses JX-GFP and TG6002 in a human melanoma in vitro model: studying immunogenic cell death, dendritic cell maturation and interaction with cytotoxic T lymphocytes

Heinrich B, Klein J, Delic M, Goepfert K, Engel V, Geberzahn L, Lusky M, Erbs P, Preville X, Moehler M

OncoTargets and Therapy 2017, 10:2389-2401

Published Date: 2 May 2017

Original Research

Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells

Feng S, Wang Y, Zhang R, Yang G, Liang Z, Wang Z, Zhang G

OncoTargets and Therapy 2017, 10:2377-2388

Published Date: 2 May 2017

Original Research

Knockdown of a DIS3L2 promoter upstream long noncoding RNA (AC105461.1) enhances colorectal cancer stem cell properties in vitro by down-regulating DIS3L2

Liu W, Yu Q, Ma J, Cheng Y, Zhang H, Luo W, Yao J, Zhang H

OncoTargets and Therapy 2017, 10:2367-2376

Published Date: 2 May 2017

Corrigendum

Lead identification for the K-Ras protein: virtual screening and combinatorial fragment-based approaches [Corrigendum]

Pathan AAK, Panthi B, Khan Z, Koppula PR, Alanazi M, Sachchidanand, Parine NR, Chourasia M

OncoTargets and Therapy 2017, 10:2365-2366

Published Date: 28 April 2017

Review

Immune checkpoint blockade: the role of PD-1-PD-L axis in lymphoid malignancies

Ilcus C, Bagacean C, Tempescul A, Popescu C, Parvu A, Cenariu M, Bocsan C, Zdrenghea M

OncoTargets and Therapy 2017, 10:2349-2363

Published Date: 28 April 2017

Original Research

Epithelial-to-mesenchymal transition correlates with gefitinib resistance in NSCLC cells and the liver X receptor ligand GW3965 reverses gefitinib resistance through inhibition of vimentin

Hu Y, Zang J, Qin X, Yan D, Cao H, Zhou L, Ni J, Yu S, Wu J, Feng JF

OncoTargets and Therapy 2017, 10:2341-2348

Published Date: 28 April 2017

Original Research

The effectiveness of EGFR-TKIs against brain metastases in EGFR mutation-positive non-small-cell lung cancer

Bai H, Xiong L, Han B

OncoTargets and Therapy 2017, 10:2335-2340

Published Date: 27 April 2017

Original Research

No genetic relationship between TLR2 rs4696480, rs3804100, and rs3804099 gene polymorphisms and female breast cancer in Saudi populations

Semlali A, Almutairi M, Parine NR, Al Amri A, Shaik JP, Al Naeem A, Abdulla Ajaj S, Rouabhia M, Alanazi MS

OncoTargets and Therapy 2017, 10:2325-2333

Published Date: 27 April 2017

Corrigendum

B-cell-specific Moloney murine leukemia virus integration site 1: potential stratification factor and therapeutic target for epithelial ovarian cancer [Corrigendum]

Zhao Q, Gui T, Qian Q, Li L, Shen K

OncoTargets and Therapy 2017, 10:2323-2324

Published Date: 27 April 2017

Original Research

Identification of potential biomarkers and analysis of prognostic values in head and neck squamous cell carcinoma by bioinformatics analysis

Yang B, Chen Z, Huang Y, Han G, Li W

OncoTargets and Therapy 2017, 10:2315-2321

Published Date: 26 April 2017

Original Research

Maintenance therapy with all-trans retinoic acid and arsenic trioxide improves relapse-free survival in adults with low- to intermediate-risk acute promyelocytic leukemia who have achieved complete remission after consolidation therapy

Liang B, Zheng ZY, Shi YF, Chen JJ, Hu XD, Qian HL, Shen ZJ, Jiang SF, Yu K, Feng JH

OncoTargets and Therapy 2017, 10:2305-2313

Published Date: 26 April 2017

Original Research

Role of CT scan in differentiating the type of colorectal cancer

Li ZH, You DY, Gao DP, Yang GJ, Dong XX, Zhang DF, Ding YY

OncoTargets and Therapy 2017, 10:2297-2303

Published Date: 26 April 2017

Case report

Apatinib to combat EGFR-TKI resistance in an advanced non-small cell lung cancer patient with unknown EGFR status: a case report

Peng Y, Cui H, Liu Z, Liu D, Liu F, Song Y, Duan H, Qiu Y, Li Q

OncoTargets and Therapy 2017, 10:2289-2295

Published Date: 26 April 2017

Original Research

Treatment-related severe and fatal adverse events with molecular targeted agents in the treatment of advanced gastric cancer: a meta-analysis

Wang L, Liu Y, Zhou W, Li W

OncoTargets and Therapy 2017, 10:2281-2287

Published Date: 26 April 2017

Original Research

Meta-analysis of the impact of de novo and acquired EGFR T790M mutations on the prognosis of patients with non-small cell lung cancer receiving EGFR-TKIs

Liu Y, Sun L, Xiong Z, Sun X, Zhang S, Ma J, Han C

OncoTargets and Therapy 2017, 10:2267-2279

Published Date: 24 April 2017

Original Research

Results of adjuvant radiation therapy for locoregional perihilar cholangiocarcinoma after curative intent resection

Leng KM, Liu YP, Wang ZD, Zhong XY, Liao GQ, Kang PC, Cui YF, Jiang XM

OncoTargets and Therapy 2017, 10:2257-2266

Published Date: 21 April 2017

Original Research

Relationship between computed tomography morphology and prognosis of patients with stage I non-small cell lung cancer

Ma J, Yang Y, Wang Y, Zhang X, Gu X, Wang Z

OncoTargets and Therapy 2017, 10:2249-2256

Published Date: 21 April 2017

Original Research

PIK3CA expression in diffuse large B cell lymphoma tissue and the effect of its knockdown in vitro

Cui W, Zheng S, Liu Z, Wang W, Cai Y, Bi R, Cao B, Zhou X

OncoTargets and Therapy 2017, 10:2239-2247

Published Date: 20 April 2017

Original Research

Novel role of granulocyte-macrophage colony-stimulating factor: antitumor effects through inhibition of epithelial-to-mesenchymal transition in esophageal cancer

Zhang J, Liu Q, Qiao L, Hu P, Deng G, Liang N, Xie J, Luo H, Zhang J

OncoTargets and Therapy 2017, 10:2227-2237

Published Date: 20 April 2017

Original Research

NVP-AUY922, a novel HSP90 inhibitor, inhibits the progression of malignant pheochromocytoma in vitro and in vivo

Lian JP, Lin D, Xie X, Xu Y, Xu L, Meng L, Zhu Y

OncoTargets and Therapy 2017, 10:2219-2226

Published Date: 19 April 2017

Original Research

Radiobiological evaluation of simultaneously dose-escalated versus non-escalated intensity-modulated radiation therapy for patients with upper thoracic esophageal cancer

Huang BT, Wu LL, Guo LJ, Xu LY, Huang RH, Lin PX, Chen JZ, Li DR, Chen CZ

OncoTargets and Therapy 2017, 10:2209-2217

Published Date: 19 April 2017

Original Research

Impact of platelet to lymphocyte ratio and metabolic syndrome on the prognosis of colorectal cancer patients

You J, Zhang H, Shen Y, Chen C, Liu W, Zheng M, Van Poucke S, Guo G, Huang Z

OncoTargets and Therapy 2017, 10:2199-2208

Published Date: 18 April 2017

Original Research

Allergic conditions are not associated with the risk of non-Hodgkin’s lymphoma or Hodgkin’s lymphoma: a systematic review and meta-analysis

Yang J, Xu H, Liang X, Lv S, Lin B, Jia Y

OncoTargets and Therapy 2017, 10:2189-2198

Published Date: 18 April 2017

Review

Novel insights into circular RNAs in clinical application of carcinomas

Rong D, Tang W, Li Z, Zhou J, Shi J, Wang H, Cao H

OncoTargets and Therapy 2017, 10:2183-2188

Published Date: 18 April 2017

Original Research

Serpin peptidase inhibitor, clade A member 3 (SERPINA3), is overexpressed in glioma and associated with poor prognosis in glioma patients

Luo D, Chen W, Tian Y, Li J, Xu X, Chen C, Li F

OncoTargets and Therapy 2017, 10:2173-2181

Published Date: 18 April 2017

Review

Monosomal karyotype in myeloid neoplasias: a literature review

Anelli L, Pasciolla C, Zagaria A, Specchia G, Albano F

OncoTargets and Therapy 2017, 10:2163-2171

Published Date: 20 April 2017

Original Research

Prognostic value of pretreatment albumin–globulin ratio in predicting long-term mortality in gastric cancer patients who underwent D2 resection

Liu J, Chen S, Geng Q, Liu X, Kong P, Zhan Y, Xu D

OncoTargets and Therapy 2017, 10:2155-2162

Published Date: 13 April 2017

Original Research

Soluble cytotoxic T-lymphocyte antigen 4: a favorable predictor in malignant tumors after therapy

Liu Q, Hu P, Deng G, Zhang J, Liang N, Xie J, Qiao L, Luo H, Zhang J

OncoTargets and Therapy 2017, 10:2147-2154

Published Date: 12 April 2017

Original Research

Inhibition of PCSK9 protects against radiation-induced damage of prostate cancer cells

Gan S, Ye J, Wang L, Qu F, Chu C, Tian Y, Yang W, Cui X

OncoTargets and Therapy 2017, 10:2139-2146

Published Date: 12 April 2017

Original Research

miR-762 can negatively regulate menin in ovarian cancer

Hou R, Yang Z, Wang S, Chu D, Liu Q, Liu J, Jiang L

OncoTargets and Therapy 2017, 10:2127-2137

Published Date: 12 April 2017

Original Research

A blockade of PD-L1 produced antitumor and antimetastatic effects in an orthotopic mouse pancreatic cancer model via the PI3K/AkT/MTOR signaling pathway

Zhao L, Li C, Liu F, Zhao Y, Liu J, Hua Y, Liu J, Huang J, Ge C

OncoTargets and Therapy 2017, 10:2115-2126

Published Date: 12 April 2017

Original Research

Gastric cancer, nutritional status, and outcome

Liu X, Qiu H, Kong P, Zhou Z, Sun X

OncoTargets and Therapy 2017, 10:2107-2114

Published Date: 12 April 2017

Review

Targeting the PD-1 pathway in pediatric solid tumors and brain tumors

Wagner LM, Adams VR

OncoTargets and Therapy 2017, 10:2097-2106

Published Date: 12 April 2017

Review

Can involved-field irradiation replace elective nodal irradiation in chemoradiotherapy for esophageal cancer? A systematic review and meta-analysis

Wang X, Miao C, Chen Z, Li W, Yuan S, Yu J, Hu X

OncoTargets and Therapy 2017, 10:2087-2095

Published Date: 11 April 2017

Original Research

Expression and activity of the urokinase plasminogen activator system in canine primary brain tumors

Rossmeisl JH, Hall-Manning K, Robertson JL, King JN, Davalos RV, Debinski W, Elankumaran S

OncoTargets and Therapy 2017, 10:2077-2085

Published Date: 12 April 2017

Original Research

Therapeutic outcome of nasopharyngeal carcinoma with cranial nerve palsy: a single institution experience of 104 patients

Huang CC, Fang FM, Chen HC, Hsu HC, Huang TL, Su YL, Chang YC

OncoTargets and Therapy 2017, 10:2069-2075

Published Date: 10 April 2017

Editorial

The role of KPNβ1 in neuro-oncology

Lilley M, Farassati F

OncoTargets and Therapy 2017, 10:2067-2068

Published Date: 10 April 2017

Review

Spotlight on bevacizumab and its potential in the treatment of malignant pleural mesothelioma: the evidence to date

Levin PA, Dowell JE

OncoTargets and Therapy 2017, 10:2057-2066

Published Date: 7 April 2017

Original Research

Silencing CDR1as inhibits colorectal cancer progression through regulating microRNA-7

Tang W, Ji M, He G, Yang L, Niu Z, Jian M, Wei Y, Ren L, Xu J

OncoTargets and Therapy 2017, 10:2045-2056

Published Date: 7 April 2017

Review

Patient considerations in metastatic colorectal cancer – role of panitumumab

Rogers JE

OncoTargets and Therapy 2017, 10:2033-2044

Published Date: 7 April 2017

Original Research

Expression and significance of GRHL2 in esophageal cancer

Shao CC, Ji CS, Wang XQ, Hu B

OncoTargets and Therapy 2017, 10:2025-2031

Published Date: 7 April 2017

Original Research

REG3A promotes the proliferation, migration, and invasion of gastric cancer cells

Chen ZF, Huang ZM, Xue HB, Lin XQ, Chen RP, Chen MJ, Jin RF

OncoTargets and Therapy 2017, 10:2017-2023

Published Date: 6 April 2017

Review

Role of postmastectomy radiotherapy in early-stage (T1–2N0–1M0) triple-negative breast cancer: a systematic review

Chen F, Pu F

OncoTargets and Therapy 2017, 10:2009-2016

Published Date: 6 April 2017

Original Research

Altered status of programmed death-ligand 1 after recurrence in resected lung adenocarcinoma patients

Chen J, Li H, Pang RL, Huang J

OncoTargets and Therapy 2017, 10:2003-2007

Published Date: 6 April 2017

Original Research

Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer

Yan CS, Jiang Y, Wan YC, Zhang L, Liu JH, Zhou SL, Cheng WJ

OncoTargets and Therapy 2017, 10:1993-2002

Published Date: 6 April 2017

Review

The activity, safety, and evolving role of brigatinib in patients with ALK-rearranged non-small cell lung cancers

Sabari JK, Santini FC, Schram AM, Bergagnini I, Chen R, Mrad C, Lai WV, Arbour KC, Drilon A

OncoTargets and Therapy 2017, 10:1983-1992

Published Date: 6 April 2017

Original Research

Serum galectin-1 in patients with multiple myeloma: associations with survival, angiogenesis, and biomarkers of macrophage activation

Andersen MN, Ludvigsen M, Abildgaard N, Petruskevicius I, Hjortebjerg R, Bjerre M, Honoré B, Møller HJ, Andersen NF

OncoTargets and Therapy 2017, 10:1977-1982

Published Date: 4 April 2017

Original Research

HSD17B12 gene rs11037575 C>T polymorphism confers neuroblastoma susceptibility in a Southern Chinese population

Zhang ZR, Zou Y, Zhu JH, Zhang RZ, Yang TY, Wang FH, Xia HM, He J, Feng ZC

OncoTargets and Therapy 2017, 10:1969-1975

Published Date: 4 April 2017

Original Research

Exploratory cohort study and meta-analysis of BIM deletion polymorphism in patients with epidermal growth factor receptor-mutant non-small-cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors

Sun S, Yu H, Wang H, Zhao X, Zhao X, Wu X, Qiao J, Chang J, Wang J

OncoTargets and Therapy 2017, 10:1955-1967

Published Date: 3 April 2017

Original Research

Clinical significance of serum cathepsin B and cystatin C levels and their ratio in the prognosis of patients with esophageal cancer

Yan Y, Zhou K, Wang L, Wang F, Chen X, Fan Q

OncoTargets and Therapy 2017, 10:1947-1954

Published Date: 3 April 2017

Original Research

Apoptotic and genomic effects of corilagin on SKOV3 ovarian cancer cell line

Attar R, Cincin ZB, Bireller ES, Cakmakoglu B

OncoTargets and Therapy 2017, 10:1941-1946

Published Date: 31 March 2017

Original Research

FAM172A expression in circulating tumor cells for prediction of high-risk subgroups of colorectal cancer

Xu C, Zhang C, Wang H, Yang H, Li G, Fei Z, Li W

OncoTargets and Therapy 2017, 10:1933-1939

Published Date: 30 March 2017

Original Research

Non-small-cell lung cancer cell lines A549 and NCI-H460 express hypoxanthine guanine phosphoribosyltransferase on the plasma membrane

Townsend MH, Anderson MD, Weagel EG, Velazquez EJ, Weber KS, Robison RA, O'Neill KL

OncoTargets and Therapy 2017, 10:1921-1932

Published Date: 30 March 2017

Original Research

Expression of SHP-1 and SOCS6 in patients with acute leukemia and their clinical implication

Liu J, Zheng Y, Gao J, Zhu G, Gao K, Zhang W, Shi F, Shi Q

OncoTargets and Therapy 2017, 10:1915-1920

Published Date: 29 March 2017

Review

Spotlight on ibrutinib and its potential in frontline treatment of chronic lymphocytic leukemia

Khan M, Gibbons JL, Ferrajoli A

OncoTargets and Therapy 2017, 10:1909-1914

Published Date: 29 March 2017

Original Research

Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer in China: a meta-analysis

Liu Y, Mu Y, Zhang A, Ren SD, Wang WH, Xie JP, Zhang YX, Zhou CH

OncoTargets and Therapy 2017, 10:1897-1908

Published Date: 29 March 2017

Original Research

Clinical course and outcome of patients with high-level microsatellite instability cancers in a real-life setting: a retrospective analysis

Halpern N, Goldberg Y, Kadouri L, Duvdevani M, Hamburger T, Peretz T, Hubert A

OncoTargets and Therapy 2017, 10:1889-1896

Published Date: 29 March 2017

Original Research

Genetic variants and increased risk of meningioma: an updated meta-analysis

Han X, Wang W, Wang L, Wang X, Li G

OncoTargets and Therapy 2017, 10:1875-1888

Published Date: 28 March 2017

Original Research

DNMT1 regulates human endometrial carcinoma cell proliferation

Wang X, Li B

OncoTargets and Therapy 2017, 10:1865-1873

Published Date: 29 March 2017

Original Research

EGFR mutation in squamous cell carcinoma of the lung: does it carry the same connotation as in adenocarcinomas?

Joshi A, Zanwar S, Noronha V, Patil VM, Chougule A, Kumar R, Janu A, Mahajan A, Kapoor A, Prabhash K

OncoTargets and Therapy 2017, 10:1859-1863

Published Date: 28 March 2017

Case report

Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report and review of the literature

Sheng Q, Xu W, Liu J, Shen B, Deng X, Wu Y, Wu W, Yu S, Wang X, Lv Z

OncoTargets and Therapy 2017, 10:1853-1858

Published Date: 27 March 2017

Original Research

Long noncoding RNA LINC01296 is associated with poor prognosis in prostate cancer and promotes cancer-cell proliferation and metastasis

Wu J, Cheng G, Zhang C, Zheng Y, Xu H, Yang H, Hua L

OncoTargets and Therapy 2017, 10:1843-1852

Published Date: 27 March 2017

Original Research

Predictive parameters in hypofractionated whole-breast 3D conformal radiotherapy according to the Ontario Canadian trial

Lazzari G, Terlizzi A, Della Vittoria Scarpati G, Perri F, De Chiara V, Turi B, Silvano G

OncoTargets and Therapy 2017, 10:1835-1842

Published Date: 24 March 2017

Original Research

Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

Xu X, Shen H, Zhu L, Lu J, Zhang L, Luo Z, Wu Y

OncoTargets and Therapy 2017, 10:1827-1834

Published Date: 23 March 2017

Original Research

Salvage treatment with apatinib for advanced non-small-cell lung cancer

Song Z, Yu X, Lou G, Shi X, Zhang Y

OncoTargets and Therapy 2017, 10:1821-1825

Published Date: 23 March 2017

Original Research

Role of Nrf2 signaling pathway in the radiation tolerance of patients with head and neck squamous cell carcinoma: an in vivo and in vitro study

Wang T, Hu P, Li B, Zhang J, Cheng Y, Liang Y

OncoTargets and Therapy 2017, 10:1809-1819

Published Date: 23 March 2017

Review

Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy

Robainas M, Otano R, Bueno S, Ait-Oudhia S

OncoTargets and Therapy 2017, 10:1803-1807

Published Date: 23 March 2017

Original Research

Associations of NQO1 C609T and NQO1 C465T polymorphisms with acute leukemia risk: a PRISMA-compliant meta-analysis

He H, Zhai X, Liu X, Zheng J, Zhai Y, Gao F, Chen Y, Lu J

OncoTargets and Therapy 2017, 10:1793-1801

Published Date: 23 March 2017

Original Research

Focal adhesion kinases crucially regulate TGFβ-induced migration and invasion of bladder cancer cells via Src kinase and E-cadherin

Kong D, Chen F, Sima N

OncoTargets and Therapy 2017, 10:1783-1792

Published Date: 23 March 2017

Original Research

Prognostic value of FOXQ1 in patients with malignant solid tumors: a meta-analysis

Cui X, Zhang J, Lv J, Yan Y, Liu X, Wang J, Lv Y, Zhang J

OncoTargets and Therapy 2017, 10:1777-1781

Published Date: 23 March 2017

Original Research

Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer

Shi L, Zheng H, Hu W, Zhou B, Dai X, Zhang Y, Liu Z, Wu X, Zhao C, Liang G

OncoTargets and Therapy 2017, 10:1767-1776

Published Date: 23 March 2017

Review

Epidermal growth factor receptor T790M mutation-positive metastatic non-small-cell lung cancer: focus on osimertinib (AZD9291)

Saad N, Poudel A, Basnet A, Gajra A

OncoTargets and Therapy 2017, 10:1757-1766

Published Date: 22 March 2017

Original Research

Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis

Xia S, Wang C, Postma EL, Yang Y, Ni X, Zhan W

OncoTargets and Therapy 2017, 10:1743-1755

Published Date: 22 March 2017

Original Research

The coexpression of EphB4 and EphrinB2 is associated with poor prognosis in HER2-positive breast cancer

Li X, Song C, Huang G, Sun S, Qiao J, Zhao J, Zhao Z, Li M

OncoTargets and Therapy 2017, 10:1735-1742

Published Date: 21 March 2017

Original Research

The associations between five polymorphisms of vascular endothelial growth factor and renal cell carcinoma risk: an updated meta-analysis

Wang J, Shen CX, Fu Y, Yu T, Song J

OncoTargets and Therapy 2017, 10:1725-1734

Published Date: 21 March 2017

Original Research

Diagnostic and prognostic roles of IRAK1 in hepatocellular carcinoma tissues: an analysis of immunohistochemistry and RNA-sequencing data from the cancer genome atlas

Ye ZH, Gao L, Wen DY, He Y, Pang YY, Chen G

OncoTargets and Therapy 2017, 10:1711-1723

Published Date: 21 March 2017

Corrigendum

Efficacy and safety of icotinib in patients with brain metastases from lung adenocarcinoma [Corrigendum]

Xu J, Liu X, Yang S, Zhang X, Shi Y

OncoTargets and Therapy 2017, 10:1709-1710

Published Date: 21 March 2017

Corrigendum

Primary neuroendocrine breast carcinomas: a retrospective analysis and review of literature [Corrigendum]

Yang X, Cao YD, Chen C, Liu L, Wang C, Liu SC

OncoTargets and Therapy 2017, 10:1707-1708

Published Date: 21 March 2017

Original Research

Suppression of microRNA-629 enhances sensitivity of cervical cancer cells to 1′S-1′-acetoxychavicol acetate via regulating RSU1

Phuah NH, Azmi MN, Awang K, Nagoor NH

OncoTargets and Therapy 2017, 10:1695-1705

Published Date: 20 March 2017

Case Series

Primary pancreatic lymphoma: two case reports and a literature review

Yu L, Chen Y, Xing L

OncoTargets and Therapy 2017, 10:1687-1694

Published Date: 20 March 2017

Original Research

Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma

Ning X, Deng Y

OncoTargets and Therapy 2017, 10:1673-1686

Published Date: 20 March 2017

Review

Role of cytokines and chemokines in alcohol-induced tumor promotion

Chen D, Zhang F, Ren H, Luo J, Wang S

OncoTargets and Therapy 2017, 10:1665-1671

Published Date: 17 March 2017

Original Research

Human omental adipose-derived mesenchymal stem cell-conditioned medium alters the proteomic profile of epithelial ovarian cancer cell lines in vitro

Zhang YL, Dong WH, Wang JJ, Cai J, Wang ZH

OncoTargets and Therapy 2017, 10:1655-1663

Published Date: 17 March 2017

Review

Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas

Jain S, Song R, Xie J

OncoTargets and Therapy 2017, 10:1645-1653

Published Date: 16 March 2017

Original Research

Evaluation of efficacy of transcatheter arterial chemoembolization for hepatocellular carcinoma using magnetic resonance diffusion-weighted imaging

Wu X, Wang J, Ji J, Chen M, Song J

OncoTargets and Therapy 2017, 10:1637-1643

Published Date: 16 March 2017

Original Research

MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro

Zhou K, Fan Y, Wu P, Duysenbi S, Feng Z, Du G, Zhang T

OncoTargets and Therapy 2017, 10:1625-1635

Published Date: 16 March 2017

Original Research

CDKL1 promotes tumor proliferation and invasion in colorectal cancer

Qin C, Ren L, Ji M, Lv S, Wei Y, Zhu D, Lin Q, Xu P, Chang W, Xu J

OncoTargets and Therapy 2017, 10:1613-1624

Published Date: 16 March 2017

Original Research

TCF21 functions as a tumor suppressor in colorectal cancer through inactivation of PI3K/AKT signaling

Dai Y, Duan H, Duan C, Zhu H, Zhou R, Pei H, Shen L

OncoTargets and Therapy 2017, 10:1603-1611

Published Date: 14 March 2017

Review

Retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia: current perspectives

McCulloch D, Brown C, Iland H

OncoTargets and Therapy 2017, 10:1585-1601

Published Date: 14 March 2017

Original Research

SDF1-3'A polymorphism is associated with increased risk of hematological malignancy: a meta-analysis

Zhang X, Fan Y, Li Z

OncoTargets and Therapy 2017, 10:1575-1583

Published Date: 14 March 2017

Review

Mechanism of immune evasion in breast cancer

Wang M, Zhang C, Song Y, Wang Z, Wang Y, Luo F, Xu Y, Zhao Y, Wu Z, Xu Y

OncoTargets and Therapy 2017, 10:1561-1573

Published Date: 14 March 2017

Original Research

Knockdown of IQGAP1 inhibits proliferation and epithelial–mesenchymal transition by Wnt/β-catenin pathway in thyroid cancer

Su D, Liu Y, Song T

OncoTargets and Therapy 2017, 10:1549-1559

Published Date: 13 March 2017

Original Research

Risk of subsequent primary malignancies among patients with prior colorectal cancer: a population-based cohort study

Yang J, Li S, Lv M, Wu Y, Chen Z, Shen Y, Wang B, Chen L, Yi M, Yang J

OncoTargets and Therapy 2017, 10:1535-1548

Published Date: 13 March 2017

Original Research

Tyrosine kinase domain mutations of EGFR gene in head and neck squamous cell carcinoma

Vatte C, Al Amri AM, Cyrus C, Chathoth S, Acharya S, Hashim TM, Al Ali Z, Alshreadah ST, Alsayyah A, Al-Ali AK

OncoTargets and Therapy 2017, 10:1527-1533

Published Date: 13 March 2017

Case report

Apatinib treatment combined with chemotherapy for advanced epithelial ovarian cancer: a case report

Deng L, Wang Y, Lu W, Liu Q, Wu J, Jin J

OncoTargets and Therapy 2017, 10:1521-1525

Published Date: 13 March 2017

Retraction

MTA1 promotes proliferation and invasion in human gastric cancer cells [Retraction]

Yao Y, Feng S, Xiao M, Li Y, Yang L, Gong J

OncoTargets and Therapy 2017, 10:1519-1520

Published Date: 10 March 2017

Original Research

Adverse prognostic impact of TGFB1 T869C polymorphism in non-small-cell lung cancer

Sang Y, Bi X, Liu Y, Zhang W, Wang D

OncoTargets and Therapy 2017, 10:1513-1518

Published Date: 10 March 2017

Original Research

Silencing Trim59 inhibits invasion/migration and epithelial-to-mesenchymal transition via TGF-β/Smad2/3 signaling pathway in bladder cancer cells

Chen W, Zhao K, Miao C, Xu A, Zhang J, Zhu J, Su S, Wang Z

OncoTargets and Therapy 2017, 10:1503-1512

Published Date: 9 March 2017

Review

Spotlight on atezolizumab and its potential in the treatment of advanced urothelial bladder cancer

Aydin AM, Woldu SL, Hutchinson RC, Boegemann M, Bagrodia A, Lotan Y, Margulis V, Krabbe LM

OncoTargets and Therapy 2017, 10:1487-1502

Published Date: 9 March 2017

Original Research

Investigating the expression, effect and tumorigenic pathway of PADI2 in tumors

Guo W, Zheng YB, Xu B, Ma F, Li C, Zhang XQ, Wang Y, Chang XT

OncoTargets and Therapy 2017, 10:1475-1485

Published Date: 8 March 2017

Original Research

Pancreatic neuroendocrine neoplasms at magnetic resonance imaging: comparison between grade 3 and grade 1/2 tumors

Guo C, Chen X, Xiao W, Wang Q, Sun K, Wang Z

OncoTargets and Therapy 2017, 10:1465-1474

Published Date: 7 March 2017

Original Research

Chronological changes in lung cancer surgery in a single Japanese institution

Nakamura H, Sakai H, Kimura H, Miyazawa T, Marushima H, Saji H

OncoTargets and Therapy 2017, 10:1459-1464

Published Date: 6 March 2017

Original Research

Arm lymphoscintigraphy after axillary lymph node dissection or sentinel lymph node biopsy in breast cancer

Sarri AJ, Dias R, Laurienzo CE, Gonçalves MCP, Dias DS, Moriguchi SM

OncoTargets and Therapy 2017, 10:1451-1457

Published Date: 6 March 2017

Original Research

Serum liver enzymes serve as prognostic factors in patients with intrahepatic cholangiocarcinoma

Zhang C, Wang H, Ning Z, Xu L, Zhuang L, Wang P, Meng Z

OncoTargets and Therapy 2017, 10:1441-1449

Published Date: 6 March 2017

Review

GSTM1 polymorphism is related to risks of nasopharyngeal cancer and laryngeal cancer: a meta-analysis

Zhang F, Wu X, Niu J, Kang X, Cheng L, Lv Y, Wu M

OncoTargets and Therapy 2017, 10:1433-1440

Published Date: 6 March 2017

Original Research

MicroRNA 543 suppresses breast cancer cell proliferation, blocks cell cycle and induces cell apoptosis via direct targeting of ERK/MAPK

Chen P, Xu W, Luo Y, Zhang Y, He Y, Yang S, Yuan Z

OncoTargets and Therapy 2017, 10:1423-1431

Published Date: 6 March 2017

Review

Safety, efficacy, and clinical utility of asparaginase in the treatment of adult patients with acute lymphoblastic leukemia

Koprivnikar J, McCloskey J, Faderl S

OncoTargets and Therapy 2017, 10:1413-1422

Published Date: 6 March 2017

Review

Nonalcoholic steatohepatitis-related hepatocellular carcinoma: is there a role for the androgen receptor pathway?

Ali MA, Lacin S, Abdel-Wahab R, Uemura M, Hassan M, Rashid A, Duda DG, Kaseb AO

OncoTargets and Therapy 2017, 10:1403-1412

Published Date: 3 March 2017

Original Research

HMGB1 is negatively correlated with the development of endometrial carcinoma and prevents cancer cell invasion and metastasis by inhibiting the process of epithelial-to-mesenchymal transition

Luan XR, Ma CJ, Wang P, Lou FL

OncoTargets and Therapy 2017, 10:1389-1402

Published Date: 3 March 2017

Review

Arterial stiffness in hematologic malignancies

Mozos I, Borzak G, Caraba A, Mihaescu R

OncoTargets and Therapy 2017, 10:1381-1388

Published Date: 3 March 2017

Case Series

The world of targeted therapies in kidney cancers: pitfalls, tips and tricks

Vallard A, Trone JC, Langrand-Escure J, Espenel S, Guy JB, Rancoule C, Xia YX, El Meddeb Hamrouni A, Ben Mrad M, Magné N

OncoTargets and Therapy 2017, 10:1375-1380

Published Date: 3 March 2017

Original Research

Prognostic value of circulating tumor cells in the peripheral blood of patients with esophageal squamous cell carcinoma

Qiao Y, Li J, Shi C, Wang W, Qu X, Xiong M, Sun Y, Li D, Zhao X, Zhang D

OncoTargets and Therapy 2017, 10:1363-1373

Published Date: 3 March 2017

Original Research

MicroRNA-148a suppresses proliferation and invasion potential of non-small cell lung carcinomas via regulation of STAT3

He M, Xue Y

OncoTargets and Therapy 2017, 10:1353-1361

Published Date: 2 March 2017

Original Research

125I brachytherapy of locally advanced non-small-cell lung cancer after one cycle of first-line chemotherapy：a comparison with best supportive care

Song J, Fan X, Zhao Z, Chen M, Chen W, Wu F, Zhang D, Chen L, Tu J, Ji J

OncoTargets and Therapy 2017, 10:1345-1352

Published Date: 2 March 2017

Original Research

Evidence from a meta-analysis: is nivolumab neurotoxic in cancer patients?

Kong X, Kong Y

OncoTargets and Therapy 2017, 10:1335-1344

Published Date: 1 March 2017

Original Research

Clarifying the molecular mechanism associated with carfilzomib resistance in human multiple myeloma using microarray gene expression profile and genetic interaction network

Zheng Z, Liu T, Zheng J, Hu J

OncoTargets and Therapy 2017, 10:1327-1334

Published Date: 1 March 2017

Original Research

Salinomycin repressed the epithelial–mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway

Li R, Dong T, Hu C, Lu J, Dai J, Liu P

OncoTargets and Therapy 2017, 10:1317-1325

Published Date: 28 February 2017

Original Research

Downregulation of long noncoding RNA HOTAIRM1 promotes monocyte/dendritic cell differentiation through competitively binding to endogenous miR-3960

Xin J, Li J, Feng Y, Wang L, Zhang Y, Yang R

OncoTargets and Therapy 2017, 10:1307-1315

Published Date: 1 March 2017

Original Research

Biosimilar Retacrit® (epoetin zeta) in the treatment of chemotherapy-induced symptomatic anemia in hematology and oncology in Germany (ORHEO) – non-interventional study

Losem C, Koenigsmann M, Rudolph C

OncoTargets and Therapy 2017, 10:1295-1305

Published Date: 28 February 2017

Original Research

Discrimination of serous cystadenoma from mucinous cystadenoma in the pancreas with contrast-enhanced ultrasonography: a prospective study in 61 patients

Sun Y, Zhou F, Liu F, Hu Y, Tan S, Liang P, Linghu EQ, Yu X

OncoTargets and Therapy 2017, 10:1285-1294

Published Date: 28 February 2017

Original Research

Sequential treatment of tyrosine kinase inhibitor and platinum-based doublet chemotherapy on EGFR mutant non-small cell lung cancer: a meta-analysis of randomized controlled clinical trials

Qiao L, Wang J, Long G, Jiang Y

OncoTargets and Therapy 2017, 10:1279-1284

Published Date: 28 February 2017

Original Research

MicroRNA-194 modulates epithelial–mesenchymal transition in human colorectal cancer metastasis

Cai H, Chen X, Tang Y, Deng Y

OncoTargets and Therapy 2017, 10:1269-1278

Published Date: 28 February 2017

Original Research

Arenobufagin activates p53 to trigger esophageal squamous cell carcinoma cell apoptosis in vitro and in vivo

Lv J, Lin S, Peng P, Cai C, Deng J, Wang M, Li X, Lin R, Lin Y, Fang A, Li Q

OncoTargets and Therapy 2017, 10:1261-1267

Published Date: 28 February 2017

Original Research

Application of carbon nanoparticles in lymph node dissection and parathyroid protection during thyroid cancer surgeries: a systematic review and meta-analysis

Wang L, Yang D, Lv JY, Yu D, Xin SJ

OncoTargets and Therapy 2017, 10:1247-1260

Published Date: 27 February 2017

Original Research

miR-204-5p acts as a tumor suppressor by targeting matrix metalloproteinases-9 and B-cell lymphoma-2 in malignant melanoma

Luan WK, Qian Y, Ni X, Bu XF, Xia Y, Wang JL, Ruan HR, Ma SJ, Xu B

OncoTargets and Therapy 2017, 10:1237-1246

Published Date: 27 February 2017

Original Research

A new tumor suppressor lncRNA RP11-190D6.2 inhibits the proliferation, migration, and invasion of epithelial ovarian cancer cells

Tong W, Yang L, Yu Q, Yao J, He A

OncoTargets and Therapy 2017, 10:1227-1235

Published Date: 27 February 2017

Original Research

The expression of aplysia ras homolog I (ARHI) and its inhibitory effect on cell biological behavior in esophageal squamous cell carcinoma

Mao Y, Han Y, Shi W

OncoTargets and Therapy 2017, 10:1217-1226

Published Date: 27 February 2017

Original Research

Toll-like receptor-4 as a predictor of clinical outcomes of estrogen receptor-negative breast cancer in Saudi women

Semlali A, Jalouli M, Parine NR, Al Amri A, Arafah M, Al Naeem A, Abdullah Ajaj S, Rouabhia M, Alanazi MS

OncoTargets and Therapy 2017, 10:1207-1216

Published Date: 24 February 2017

Original Research

Combination of preoperative CEA and CA19-9 improves prediction outcomes in patients with resectable pancreatic adenocarcinoma: results from a large follow-up cohort

Zhou G, Liu X, Wang X, Jin D, Chen Y, Li G, Li C, Fu D, Xu W, Wang X

OncoTargets and Therapy 2017, 10:1199-1206

Published Date: 24 February 2017

Original Research

Long non-coding RNA CCAT2 is associated with poor prognosis in hepatocellular carcinoma and promotes tumor metastasis by regulating Snail2-mediated epithelial–mesenchymal transition

Xu Y, Wang B, Zhang F, Wang A, Du X, Hu P, Zhu Y, Fang Z

OncoTargets and Therapy 2017, 10:1191-1198

Published Date: 24 February 2017

Original Research

Preoperative lymphocyte-to-monocyte ratio predicts survival in primary hepatitis B-virus positive hepatocellular carcinoma after curative resection

Li G, Ji J, Yang F, Xu H, Bai Y

OncoTargets and Therapy 2017, 10:1181-1189

Published Date: 23 February 2017

Original Research

Aberrant histone modification in CD19+ B cells of the patients with chronic lymphocytic leukemia

Zhou K, Zhang Q, Liu Y, Xiong Y, Wu S, Yang J, Zhou H, Liu X, Wei X, Song Y

OncoTargets and Therapy 2017, 10:1173-1179

Published Date: 23 February 2017

Original Research

Prognostic and clinicopathologic significance of neutrophil-to-lymphocyte ratio in esophageal squamous cell carcinoma: evidence from a meta-analysis

Huang Y, Sun Y, Peng P, Zhu S, Sun W, Zhang P

OncoTargets and Therapy 2017, 10:1165-1172

Published Date: 23 February 2017

Review

Update on the role of trabectedin in the treatment of intractable soft tissue sarcomas

Recine F, Bongiovanni A, Riva N, Fausti V, De Vita A, Mercatali L, Liverani C, Miserocchi G, Amadori D, Ibrahim T

OncoTargets and Therapy 2017, 10:1155-1164

Published Date: 23 February 2017

Original Research

Association between TP53 gene Arg72Pro polymorphism and Wilms’ tumor risk in a Chinese population

Fu W, Zhuo Z, Jia W, Zhu J, Zhu S, Lin Z, Wang F, Xia H, He J, Liu G

OncoTargets and Therapy 2017, 10:1149-1154

Published Date: 23 February 2017

Case report

Long-term survival after a favorable response to anti-EGFR antibody plus chemotherapy to treat bone marrow metastasis: a case report of KRAS-wildtype rectal cancer

Nakamura S, Fukui T, Suzuki S, Takeda H, Watanabe K, Yoshioka T

OncoTargets and Therapy 2017, 10:1143-1147

Published Date: 23 February 2017

Review

Intrahepatic cholangiocarcinoma: current perspectives

Buettner S, van Vugt JLA, IJzermans JNM, Groot Koerkamp B

OncoTargets and Therapy 2017, 10:1131-1142

Published Date: 22 February 2017

Original Research

Diagnostic and prognostic values of contrast-enhanced ultrasound in breast cancer: a retrospective study

Zhao YX, Liu S, Hu YB, Ge YY, Lv DM

OncoTargets and Therapy 2017, 10:1123-1129

Published Date: 22 February 2017

Original Research

miR-182 promotes tumor growth and increases chemoresistance of human anaplastic thyroid cancer by targeting tripartite motif 8

Liu Y, Zhang B, Shi T, Qin H

OncoTargets and Therapy 2017, 10:1115-1122

Published Date: 24 February 2017

Letter

Internal mammary lymph node management – further direction

Vrana D, Gatek J

OncoTargets and Therapy 2017, 10:1111-1114

Published Date: 21 February 2017

Original Research

Impact of gefitinib in early stage treatment on circulating cytokines and lymphocytes for patients with advanced non–small cell lung cancer

Sheng J, Fang W, Liu X, Xing S, Zhan J, Ma Y, Huang Y, Zhou N, Zhao H, Zhang L

OncoTargets and Therapy 2017, 10:1101-1110

Published Date: 21 February 2017

Original Research

Decrease of miR-622 expression suppresses migration and invasion by targeting regulation of DYRK2 in colorectal cancer cells

Wang Y, Sun J, Wei X, Luan L, Zeng X, Wang C, Zhao W

OncoTargets and Therapy 2017, 10:1091-1100

Published Date: 22 February 2017

Original Research

Metronomic treatment of advanced non-small-cell lung cancer with daily oral vinorelbine – a Phase I trial

Guetz S, Tufman A, von Pawel J, Rittmeyer A, Borgmeier A, Ferré P, Edlich B, Huber RM

OncoTargets and Therapy 2017, 10:1081-1089

Published Date: 21 February 2017

Original Research

SIX1 overexpression predicts poor prognosis and induces radioresistance through AKT signaling in esophageal squamous cell carcinoma

He Z, Li G, Tang L, Li Y

OncoTargets and Therapy 2017, 10:1071-1079

Published Date: 21 February 2017

Original Research

Tbx2 confers poor prognosis in glioblastoma and promotes temozolomide resistance with change of mitochondrial dynamics

Yi F, Du J, Ni W, Liu W

OncoTargets and Therapy 2017, 10:1059-1069

Published Date: 20 February 2017

Original Research

MicroRNA-320 inhibits invasion and induces apoptosis by targeting CRKL and inhibiting ERK and AKT signaling in gastric cancer cells

Zhao Y, Dong Q, Wang E

OncoTargets and Therapy 2017, 10:1049-1058

Published Date: 20 February 2017

Original Research

Prognostic significance of tumor budding and single cell invasion in gastric adenocarcinoma

Che K, Zhao Y, Qu X, Pang Z, Ni Y, Zhang T, Du J, Shen H

OncoTargets and Therapy 2017, 10:1039-1047

Published Date: 20 February 2017

Original Research

miR-195 enhances the radiosensitivity of colorectal cancer cells by suppressing CARM1

Zheng L, Chen J, Zhou Z, He Z

OncoTargets and Therapy 2017, 10:1027-1038

Published Date: 20 February 2017

Original Research

Overexpression of the long non-coding RNA, linc-UBC1, is associated with poor prognosis and facilitates cell proliferation, migration, and invasion in colorectal cancer

Gao X, Wen J, Gao P, Zhang G, Zhang G

OncoTargets and Therapy 2017, 10:1017-1026

Published Date: 22 February 2017

Original Research

Long noncoding RNA NEAT1 promotes cell proliferation and invasion by regulating hnRNP A2 expression in hepatocellular carcinoma cells

Mang YY, Li L, Ran JH, Zhang SN, Liu J, Li LB, Chen YM, Liu J, Gao Y, Ren G

OncoTargets and Therapy 2017, 10:1003-1016

Published Date: 20 February 2017

Corrigendum

Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury [Corrigendum]

Mizuno T, Sato W, Ishikawa K, Terao Y, Takahashi K, Noda Y, Yuzawa Y, Nagamatsu T

OncoTargets and Therapy 2017, 10:1001-1002

Published Date: 21 February 2017

Original Research

Prognostic role of long noncoding RNA NEAT1 in various carcinomas: a meta-analysis

Chen T, Wang H, Yang P, He ZY

OncoTargets and Therapy 2017, 10:993-1000

Published Date: 17 February 2017

Original Research

Breast and cervical cancer-screening uptake among females in Ardabil, northwest Iran: a community-based study

Farzaneh E, Heydari H, Shekarchi AA, Kamran A

OncoTargets and Therapy 2017, 10:985-992

Published Date: 17 February 2017

Original Research

Antiangiogenic drugs used with chemotherapy for patients with recurrent ovarian cancer: a meta-analysis

Yi SY, Zeng LJ, Kuang Y, Cao ZJ, Zheng CJ, Zhang Y, Liao M, Yang L

OncoTargets and Therapy 2017, 10:973-984

Published Date: 17 February 2017

Original Research

BRAFV600 mutations in solid tumors, other than metastatic melanoma and papillary thyroid cancer, or multiple myeloma: a screening study

Cohn AL, Day B, Abhyankar S, McKenna E, Riehl T, Puzanov I

OncoTargets and Therapy 2017, 10:965-971

Published Date: 17 February 2017

Original Research

Axl promotes the proliferation, invasion and migration of Wilms’ tumor and can be used as a prognostic factor

Zhu S, Liu G, Fu W, Hu J, Fu K, Jia W

OncoTargets and Therapy 2017, 10:955-963

Published Date: 16 February 2017

Original Research

Effectiveness of circulating tumor DNA for detection of KRAS gene mutations in colorectal cancer patients: a meta-analysis

Hao Y, Fu Q, Guo Y, Ye M, Zhao H, Wang Q, Peng X, Li Q, Wang R, Xiao W

OncoTargets and Therapy 2017, 10:945-953

Published Date: 16 February 2017

Original Research

Polydatin regulates proliferation, apoptosis and autophagy in multiple myeloma cells through mTOR/p70s6k pathway

Yang B, Zhao S

OncoTargets and Therapy 2017, 10:935-944

Published Date: 16 February 2017

Original Research

The superiority of 256-slice spiral computed tomography angiography for preoperative evaluation of surrounding arteries in patients with gastric cancer

Wu D, Zhao L, Liu Y, Wang J, Hu W, Feng X, Lv Z, Li Y, Yao X

OncoTargets and Therapy 2017, 10:927-933

Published Date: 16 February 2017

Original Research

Increased BTLA and HVEM in gastric cancer are associated with progression and poor prognosis

Lan X, Li S, Gao H, Nanding A, Quan L, Yang C, Ding S, Xue Y

OncoTargets and Therapy 2017, 10:919-926

Published Date: 16 February 2017

Original Research

Association between VEGF–460T/C gene polymorphism and clinical outcomes of nasopharyngeal carcinoma treated with intensity-modulated radiation therapy

Tan JY, Jiang L, Cheng XW, Wang CL, Chen JS, Huang XQ, Xie P, Xia DM, Wang RS, Zhang Y

OncoTargets and Therapy 2017, 10:909-918

Published Date: 15 February 2017

Review

Carfilzomib boosted combination therapy for relapsed multiple myeloma

Steiner RE, Manasanch EE

OncoTargets and Therapy 2017, 10:895-907

Published Date: 15 February 2017

Original Research

miRNA-320a inhibits tumor proliferation and invasion by targeting c-Myc in human hepatocellular carcinoma

Xie F, Yuan Y, Xie L, Ran P, Xiang X, Huang Q, Qi G, Guo X, Xiao C, Zheng S

OncoTargets and Therapy 2017, 10:885-894

Published Date: 15 February 2017

Original Research

Prognostic value of the C-reactive protein/albumin ratio in patients with laryngeal squamous cell carcinoma

Yu S, Zhou Z, Cai Q, Liang F, Han P, Chen R, Huang X

OncoTargets and Therapy 2017, 10:879-884

Published Date: 15 February 2017

Original Research

The lymphocyte–monocyte ratio predicts tumor response and survival in patients with locally advanced esophageal cancer who received definitive chemoradiotherapy

Liu X, Li M, Zhao F, Zhu Y, Luo Y, Kong L, Zhu H, Zhang Y, Shi F, Yu J

OncoTargets and Therapy 2017, 10:871-877

Published Date: 14 February 2017

Original Research

Clinicopathological characteristics and prognostic value of cancer stem cell marker CD133 in breast cancer: a meta-analysis

Li Z, Yin SC, Zhang L, Liu WG, Chen B, Xing H

OncoTargets and Therapy 2017, 10:859-870

Published Date: 14 February 2017

Original Research

Correlations of microvascular blood flow of contrast-enhanced ultrasound and HGF/c-Met signaling pathway with clinicopathological features and prognosis of patients with hepatocellular carcinoma

Zhuang PH, Xu L, Gao L, Lu W, Ruan LT, Yang J

OncoTargets and Therapy 2017, 10:847-857

Published Date: 14 February 2017

Case Series

Successful treatment with apatinib for refractory recurrent malignant gliomas: a case series

Zhang H, Chen F, Wang Z, Wu S

OncoTargets and Therapy 2017, 10:837-845

Published Date: 14 February 2017

Review

The different functions and clinical significances of caveolin-1 in human adenocarcinoma and squamous cell carcinoma

Fu P, Chen F, Pan Q, Zhao X, Zhao C, Cho WC, Chen H

OncoTargets and Therapy 2017, 10:819-835

Published Date: 14 February 2017

Original Research

AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway

Chen JJ, Wang ZJ, Yu SS

OncoTargets and Therapy 2017, 10:811-817

Published Date: 13 February 2017

Original Research

Effects of HGF gene polymorphisms and protein expression on transhepatic arterial chemotherapeutic embolism efficacy and prognosis in patients with primary liver cancer

Chen HY, Chen YM, Wu J, Yang FC, Lv Z, Qian YG, Zheng SS

OncoTargets and Therapy 2017, 10:803-810

Published Date: 13 February 2017

Original Research

RNAi for contactin 2 inhibits proliferation of U87-glioma stem cells by downregulating AICD, EGFR, and HES1

Guo Y, Zhang PD, Zhang HT, Zhang P, Xu RX

OncoTargets and Therapy 2017, 10:791-801

Published Date: 13 February 2017

Original Research

Clinicopathological significance of ZEB-1 and E-cadherin proteins in patients with oral cavity squamous cell carcinoma

Yao X, Sun S, Zhou X, Zhang Q, Guo W, Zhang L

OncoTargets and Therapy 2017, 10:781-790

Published Date: 13 February 2017

Review

Efficacy of eribulin in breast cancer: a short report on the emerging new data

Eslamian G, Wilson C, Young RJ

OncoTargets and Therapy 2017, 10:773-779

Published Date: 13 February 2017

Original Research

Induction of PD-L1 expression by epidermal growth factor receptor–mediated signaling in esophageal squamous cell carcinoma

Zhang W, Pang Q, Yan C, Wang Q, Yang J, Yu S, Liu X, Yuan Z, Wang P, Xiao Z

OncoTargets and Therapy 2017, 10:763-771

Published Date: 13 February 2017

Original Research

MiR-99a suppresses cell invasion and metastasis in nasopharyngeal carcinoma through targeting HOXA1

Wang J, Tang W, Liao M, Liu Y, Ai X

OncoTargets and Therapy 2017, 10:753-761

Published Date: 10 February 2017

Original Research

Two SNPs in the promoter region of Toll-like receptor 4 gene are not associated with smoking in Saudi Arabia

Kohailan M, Alanazi M, Rouabhia M, Al Amri A, Parine NR, Semlali A

OncoTargets and Therapy 2017, 10:745-752

Published Date: 9 February 2017

Original Research

CUL4A promotes proliferation and metastasis of colorectal cancer cells by regulating H3K4 trimethylation in epithelial–mesenchymal transition

Sui X, Zhou H, Zhu L, Wang D, Fan S, Zhao W

OncoTargets and Therapy 2017, 10:735-743

Published Date: 9 February 2017

Original Research

Preoperative albumin-to-globulin ratio and prognostic nutrition index predict prognosis for glioblastoma

Xu WZ, Li F, Xu ZK, Chen X, Sun B, Cao JW, Liu YG

OncoTargets and Therapy 2017, 10:725-733

Published Date: 8 February 2017

Original Research

β-Catenin promotes cell proliferation, migration, and invasion but induces apoptosis in renal cell carcinoma

Yang CM, Ji S, Li Y, Fu LY, Jiang T, Meng FD

OncoTargets and Therapy 2017, 10:711-724

Published Date: 20 February 2017

Original Research

Common variations within HACE1 gene and neuroblastoma susceptibility in a Southern Chinese population

Zhang Z, Zhang R, Zhu J, Wang F, Yang T, Zou Y, He J, Xia H

OncoTargets and Therapy 2017, 10:703-709

Published Date: 8 February 2017

Original Research

ARHGAP1 overexpression inhibits proliferation, migration and invasion of C-33A and SiHa cell lines

Li JP, Liu Y, Yin YH

OncoTargets and Therapy 2017, 10:691-701

Published Date: 7 February 2017

Original Research

USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma

Chen Y, Zhou B, Chen D

OncoTargets and Therapy 2017, 10:681-689

Published Date: 7 February 2017

Original Research

miR182 activates the Ras–MEK–ERK pathway in human oral cavity squamous cell carcinoma by suppressing RASA1 and SPRED1

Wang JH, Wang W, Li JC, Wu LJ, Song M, Meng QG

OncoTargets and Therapy 2017, 10:667-679

Published Date: 7 February 2017

Original Research

Prognostic implications of Kindlin proteins in human osteosarcoma

Ning K, Zhang H, Wang Z, Li K

OncoTargets and Therapy 2017, 10:657-665

Published Date: 7 February 2017

Review

Profile of venetoclax and its potential in the context of treatment of relapsed or refractory chronic lymphocytic leukemia

Huber H, Edenhofer S, Estenfelder S, Stilgenbauer S

OncoTargets and Therapy 2017, 10:645-656

Published Date: 7 February 2017

Original Research

Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway

Cui Y, Li Q, Li H, Wang Y, Wang H, Chen W, Zhang S, Cao J, Liu T

OncoTargets and Therapy 2017, 10:627-643

Published Date: 3 February 2017

Original Research

High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma

Ren P, Chen C, Yue J, Zhang J, Yu Z

OncoTargets and Therapy 2017, 10:617-625

Published Date: 9 February 2017

Review

FLT3 inhibitors: clinical potential in acute myeloid leukemia

Hospital MA, Green AS, Maciel TT, Moura IC, Leung AY, Bouscary D, Tamburini J

OncoTargets and Therapy 2017, 10:607-615

Published Date: 3 February 2017

Review

Prevention and treatment of tumor lysis syndrome, and the efficacy and role of rasburicase

Alakel N, Middeke JM, Schetelig J, Bornhäuser M

OncoTargets and Therapy 2017, 10:597-605

Published Date: 2 February 2017

Original Research

nab-Paclitaxel plus gemcitabine for metastatic pancreatic cancer: a subgroup analysis of the Western European cohort of the MPACT trial

Tabernero J, Kunzmann V, Scheithauer W, Reni M, Shiansong Li J, Ferrara S, Djazouli K

OncoTargets and Therapy 2017, 10:591-596

Published Date: 2 February 2017

Original Research

Expression of microRNA-30c via lentivirus vector inhibits the proliferation and enhances the sensitivity of highly aggressive ccRCC Caki-1 cells to anticancer agents

Yang HL, Song EL, Shen GR, Zhu TH, Jiang TW, Shen H, Niu LP, Wang B, Lu ZY, Qian JP

OncoTargets and Therapy 2017, 10:579-590

Published Date: 2 February 2017

Original Research

Exploring targeted therapy of osteosarcoma using proteomics data

Chaiyawat P, Settakorn J, Sangsin A, Teeyakasem P, Klangjorhor J, Soongkhaw A, Pruksakorn D

OncoTargets and Therapy 2017, 10:565-577

Published Date: 1 February 2017

Original Research

Impact of tumor volume doubling time on post-metastatic survival in bone or soft-tissue sarcoma patients treated with metastasectomy and/or radiofrequency ablation of the lung

Nakamura T, Matsumine A, Takao M, Nakatsuka A, Matsubara T, Asanuma K, Sudo A

OncoTargets and Therapy 2017, 10:559-564

Published Date: 31 January 2017

Review

Peptide receptor radionuclide therapy in the management of gastrointestinal neuroendocrine tumors: efficacy profile, safety, and quality of life

Severi S, Grassi I, Nicolini S, Sansovini M, Bongiovanni A, Paganelli G

OncoTargets and Therapy 2017, 10:551-557

Published Date: 27 January 2017

Original Research

miR-17 as a diagnostic biomarker regulates cell proliferation in breast cancer

Yang F, Li Y, Xu L, Zhu Y, Gao H, Zhen L, Fang L

OncoTargets and Therapy 2017, 10:543-550

Published Date: 27 January 2017

Original Research

Clinical investigation into the initial diagnosis and treatment of 539 patients with stage IV lung cancer

Shao Q, Liu S, Wang W, zhang Y, Li F, Li J

OncoTargets and Therapy 2017, 10:535-541

Published Date: 31 January 2017

Original Research

The clinical significance of the Ezrin gene and circulating tumor cells in osteosarcoma

Zhong GX, Feng SD, Shen RK, Wu Z, Chen F, Zhu X

OncoTargets and Therapy 2017, 10:527-533

Published Date: 8 February 2017

Case report

Effective BRAF inhibitor vemurafenib therapy in a 2-year-old patient with sequentially diagnosed Langerhans cell histiocytosis and Erdheim–Chester disease

Váradi Z, Bánusz R, Csomor J, Kállay K, Varga E, Kertész G, Csóka M

OncoTargets and Therapy 2017, 10:521-526

Published Date: 24 January 2017

Review

Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma

Wahid M, Jawed A, Dar SA, Mandal RK, Haque S

OncoTargets and Therapy 2017, 10:515-520

Published Date: 24 January 2017

Original Research

Silencing of Foxp3 enhances the antitumor efficacy of GM-CSF genetically modified tumor cell vaccine against B16 melanoma

Miguel A, Sendra L, Noé V, Ciudad CJ, Dasi F, Hervas D, Herrero MJ, Aliño SF

OncoTargets and Therapy 2017, 10:503-514

Published Date: 23 January 2017

Original Research

Prognostic significance of microRNA-100 in solid tumors: an updated meta-analysis

Wang J, Yu M, Guan S, Zhang G, Wang J, Cheng Y

OncoTargets and Therapy 2017, 10:493-502

Published Date: 23 January 2017

Original Research

Silence of long noncoding RNA PANDAR switches low-dose curcumin-induced senescence to apoptosis in colorectal cancer cells

Chen T, Yang P, Wang H, He ZY

OncoTargets and Therapy 2017, 10:483-491

Published Date: 21 January 2017

Original Research

Parity association with clinicopathological factors in invasive breast cancer: a retrospective analysis

Shen SD, Zhong SZ, Xiao GF, Zhou HB, Huang WH

OncoTargets and Therapy 2017, 10:477-481

Published Date: 21 January 2017

Review

Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors

Zulfiqar B, Mahroo A, Nasir K, Farooq RK, Jalal N, Rashid MU, Asghar K

OncoTargets and Therapy 2017, 10:463-476

Published Date: 21 January 2017

Original Research

Parthenolide suppresses pancreatic cell growth by autophagy-mediated apoptosis

Liu W, Wang X, Sun J, Yang Y, Li W, Song J

OncoTargets and Therapy 2017, 10:453-461

Published Date: 23 January 2017

Case Series

Apatinib as post second-line therapy in EGFR wild-type and ALK-negative advanced lung adenocarcinoma

Fang S, Zhang H, Zhang Y, Xie W

OncoTargets and Therapy 2017, 10:447-452

Published Date: 18 January 2017

Original Research

Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel

Huang T, Yang L, Wang G, Ding G, Peng B, Wen Y, Wang Z

OncoTargets and Therapy 2017, 10:439-446

Published Date: 18 January 2017

Original Research

Add-on bevacizumab can prevent early clinical deterioration and prolong survival in newly diagnosed partially resected glioblastoma patients with a poor performance status

Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Shono T, Mizoguchi M, Iihara K

OncoTargets and Therapy 2017, 10:429-437

Published Date: 18 January 2017

Original Research

Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis

Liang CJ, Xu YC, Li GM, Zhao TJ, Xia F, Li GQ, Zhang D, Wu JX

OncoTargets and Therapy 2017, 10:417-428

Published Date: 18 January 2017

Original Research

Elevated serum levels of vascular endothelial growth factor predict a poor prognosis of platinum-based chemotherapy in non-small cell lung cancer

Zang JL, Hu Y, Xu XY, Ni J, Yan DL, Liu SW, He J, Xue J, Wu JZ, Feng JF

OncoTargets and Therapy 2017, 10:409-415

Published Date: 18 January 2017

Original Research

Primary neuroendocrine breast carcinomas: a retrospective analysis and review of literature

Yang X, Cao YD, Chen C, Liu L, Wang C, Liu SC

OncoTargets and Therapy 2017, 10:397-407

Published Date: 18 January 2017

Original Research

FBLN4 as candidate gene associated with long-term and short-term survival with primary glioblastoma

Li F, Li YP, Zhang K, Li Y, He P, Liu YJ, Yuan H, Lu H, Liu J, Che S, Li Z, Bie L

OncoTargets and Therapy 2017, 10:387-395

Published Date: 16 January 2017

Original Research

Overall survival in renal cell carcinoma after introduction of targeted therapies: a Norwegian population-based study

Beisland C, Johannesen TB, Klepp O, Axcrona U, Torgersen KM, Kowalski J, Solli O, Sandin R, Oldenburg J

OncoTargets and Therapy 2017, 10:371-385

Published Date: 16 January 2017

Original Research

Validation of a novel prognostic scoring system using inflammatory response biomarkers in patients undergoing curative thoracoscopic esophagectomy for esophageal squamous cell carcinoma

Hirahara N, Fujii Y, Yamamoto T, Hyakudomi R, Hirayama T, Taniura T, Ishitobi K, Tajima Y

OncoTargets and Therapy 2017, 10:363-370

Published Date: 13 January 2017

Letter

Letter to the editor regarding "Prognostic role of microRNA-150 in various carcinomas: a meta-analysis"

Li M, Yang Y

OncoTargets and Therapy 2017, 10:361-362

Published Date: 13 January 2017

Review

Advances in antiangiogenic treatment of small-cell lung cancer

Lu H, Jiang Z

OncoTargets and Therapy 2017, 10:353-359

Published Date: 12 January 2017

Review

Chidamide in the treatment of peripheral T-cell lymphoma

Chan TS, Tse E, Kwong YL

OncoTargets and Therapy 2017, 10:347-352

Published Date: 12 January 2017

Original Research

Decrease of RBM4 indicates poor prognosis in patients with hepatocellular carcinoma after hepatectomy

Chen J, Liu L, Xu J

OncoTargets and Therapy 2017, 10:339-345

Published Date: 11 January 2017

Original Research

Radiosynthesis and pharmacokinetics of [18F]fluoroethyl bufalin in hepatocellular carcinoma-bearing mice

Yang Z, Liu J, Huang Q, Zhang Z, Zhang J, Pan Y, Yang Y, Cheng D

OncoTargets and Therapy 2017, 10:329-338

Published Date: 11 January 2017

Original Research

Prognostic value and clinicopathological significance of proliferating cell nuclear antigen expression in gastric cancer: a systematic review and meta-analysis

Yin SC, Li Z, Huang JY, Miao ZF, Zhang JY, Lu CY, Xu H, Xu HM

OncoTargets and Therapy 2017, 10:319-327

Published Date: 10 January 2017

Original Research

Expression of phosphatase of regenerating liver-3 is associated with prognosis of Wilms’ tumor

Sun F, Li W, Wang L, Jiao C

OncoTargets and Therapy 2017, 10:311-317

Published Date: 10 January 2017

Original Research

Association of MTHFR C677T and A1298C polymorphisms with oral cancer susceptibility: evidence from a meta-analysis

Jiang S, Xu J, Zhuo Z, Hua Z

OncoTargets and Therapy 2017, 10:303-310

Published Date: 10 January 2017

Original Research

Clinical outcomes of patients with metachronous second primary lung adenocarcinomas

Zhao H, Yang H, Han K, Xu J, Yao F, Zhao Y, Fan L, Gu H, Shen Z

OncoTargets and Therapy 2017, 10:295-302

Published Date: 10 January 2017

Original Research

Apoptotic induction and inhibition of NF-κB signaling pathway in human prostatic cancer PC3 cells by natural compound 2,2'-oxybis (4-allyl-1-methoxybenzene), biseugenol B, from Litsea costalis: an in vitro study

Abbaspour Babaei M, Zaman Huri H, Kamalidehghan B, Yeap SK, Ahmadipour F

OncoTargets and Therapy 2017, 10:277-294

Published Date: 10 January 2017

Original Research

Correlation of SASH1 expression and ultrasonographic features in breast cancer

Gong X, Wu J, Wu J, Liu J, Gu H, Shen H

OncoTargets and Therapy 2017, 10:271-276

Published Date: 10 January 2017

Review

Strategies of temozolomide in future glioblastoma treatment

Lee CY

OncoTargets and Therapy 2017, 10:265-270

Published Date: 9 January 2017

Original Research

Basal oxidative stress ratio of head and neck squamous cell carcinomas correlates with nodal metastatic spread in patients under therapy

Dequanter D, Dok R, Nuyts S

OncoTargets and Therapy 2017, 10:259-263

Published Date: 9 January 2017

Original Research

RASSF1A promoter methylation is associated with increased risk of thyroid cancer: a meta-analysis

Shou FY, Xu F, Li G, Zhao ZH, Mao Y, Yang FF, Wang HM, Guo HY

OncoTargets and Therapy 2017, 10:247-257

Published Date: 9 January 2017

Original Research

Clinical outcomes of epidermal growth factor receptor tyrosine kinase inhibitors in recurrent adenosquamous carcinoma of the lung after resection

Fan L, Yang H, Yao F, Zhao Y, Gu H, Han K, Zhao H

OncoTargets and Therapy 2017, 10:239-245

Published Date: 6 January 2017

Original Research

MTHFR C677T polymorphism and breast, ovarian cancer risk: a meta-analysis of 19,260 patients and 26,364 controls

He L, Shen Y

OncoTargets and Therapy 2017, 10:227-238

Published Date: 6 January 2017

Original Research

VTD-melphalan is well tolerated and results in very high rates of stringent CR and MRD-negative status in multiple myeloma

Nadiminti K, Singh Abbi KK, Mott SL, Dozeman L, Tricot A, Schultz A, Behrends S, Zhan F, Tricot G

OncoTargets and Therapy 2017, 10:217-226

Published Date: 6 January 2017

Original Research

Long noncoding RNA CRNDE functions as a competing endogenous RNA to promote metastasis and oxaliplatin resistance by sponging miR-136 in colorectal cancer

Gao H, Song X, Kang T, Yan B, Feng L, Gao L, Ai L, Liu X, Yu J, Li H

OncoTargets and Therapy 2017, 10:205-216

Published Date: 5 January 2017

Original Research

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas

He T, Qiu T, Wang X, Gui H, Wang X, Hu Q, Xia H, Qi G, Wu J, Ma H

OncoTargets and Therapy 2017, 10:195-203

Published Date: 4 January 2017

Original Research

The role of microRNA-21 in predicting brain metastases from non-small cell lung cancer

Dong J, Zhang Z, Gu T, Xu SF, Dong LX, Li X, Fu BH, Fu ZZ

OncoTargets and Therapy 2017, 10:185-194

Published Date: 29 December 2016

Original Research

A comparative study of target volumes based on 18F-FDG PET-CT and ten phases of 4DCT for primary thoracic squamous esophageal cancer

Guo Y, Li J, Zhang P, Zhang Y

OncoTargets and Therapy 2017, 10:177-184

Published Date: 6 January 2017

Review

Pediatric papillary thyroid cancer: current management challenges

Verburg FA, Van Santen HM, Luster M

OncoTargets and Therapy 2017, 10:165-175

Published Date: 28 December 2016

Original Research

Clinicopathological and immunohistochemical features of lung invasive mucinous adenocarcinoma based on computed tomography findings

Shimizu K, Okita R, Saisho S, Maeda A, Nojima Y, Nakata M

OncoTargets and Therapy 2017, 10:153-163

Published Date: 28 December 2016

Clinical Trial Report

Recombinant human endostatin in combination with CHOP regimen for peripheral T cell lymphoma

Zhang Q, Cao J, Xue K, Liu X, Ji D, Guo Y, Hong X

OncoTargets and Therapy 2017, 10:145-151

Published Date: 22 December 2016

Original Research

Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells

Kwak TW, Park SB, Kim HJ, Jeong YI, Kang DH

OncoTargets and Therapy 2017, 10:137-144

Published Date: 22 December 2016

Original Research

Decreased miR-503 expression in gastric cancer is inversely correlated with serum carcinoembryonic antigen and acts as a potential prognostic and diagnostic biomarker

Wu D, Cao G, Huang Z, Jin K, Hu H, Yu J, Zeng Y

OncoTargets and Therapy 2017, 10:129-135

Published Date: 23 December 2016

Original Research

Comparing efficacy and survivals of initial treatments for elderly patients with newly diagnosed multiple myeloma: a network meta-analysis of randomized controlled trials

Liu X, Chen J, He YA, Meng X, Li K, He CK, Liu S

OncoTargets and Therapy 2017, 10:121-128

Published Date: 22 December 2016

Original Research

High expression of long noncoding RNA HULC is a poor predictor of prognosis and regulates cell proliferation in glioma

Yan H, Tian R, Zhang M, Wu J, Ding M, He J

OncoTargets and Therapy 2017, 10:113-120

Published Date: 21 December 2016

Review

nab-Paclitaxel as a potential partner with checkpoint inhibitors in solid tumors

Soliman HH

OncoTargets and Therapy 2017, 10:101-112

Published Date: 21 December 2016

Original Research

Expression of HPIP in epithelial ovarian carcinoma: a clinicopathological study

Wang Y, Meng F, Liu Y, Chen X

OncoTargets and Therapy 2017, 10:95-100

Published Date: 20 December 2016

Original Research

Reduction of AZGP1 predicts poor prognosis in esophageal squamous cell carcinoma patients in Northern China

Tang H, Wu Y, Qin Y, Wang H, Wang L, Guan X, Luo S, Wang Q

OncoTargets and Therapy 2017, 10:85-94

Published Date: 20 December 2016

Original Research

RANKL/RANK pathway abrogates cetuximab sensitivity in gastric cancer cells via activation of EGFR and c-Src

Zhang X, Song Y, Song N, Zhang Y, Zhang L, Wang Y, Wang Z, Qu X, Liu Y

OncoTargets and Therapy 2017, 10:73-83

Published Date: 5 January 2017

Case report

Nasopharyngeal carcinoma treated with bevacizumab combined with paclitaxel liposome plus cisplatin: a case report and literature review

He W, Zou C, Tian ZK, Tan WY, Shen WX, Chen JH, Liu LP, Xu RL

OncoTargets and Therapy 2017, 10:67-72

Published Date: 20 December 2016

Original Research

A novel synthetic Asiatic acid derivative induces apoptosis and inhibits proliferation and mobility of gastric cancer cells by suppressing STAT3 signaling pathway

Wang G, Jing Y, Cao LS, Gong CC, Gong ZN, Cao XR

OncoTargets and Therapy 2017, 10:55-66

Published Date: 20 December 2016

Original Research

Low PLCE1 levels are correlated with poor prognosis in hepatocellular carcinoma

Cheng Y, Xing SG, Jia WD, Huang M, Bian NN

OncoTargets and Therapy 2017, 10:47-54

Published Date: 19 December 2016

Original Research

Long noncoding RNA MALAT1-regulated microRNA 506 modulates ovarian cancer growth by targeting iASPP

Lei R, Xue M, Zhang L, Lin ZQ

OncoTargets and Therapy 2017, 10:35-46

Published Date: 19 December 2016

Case report

Atypical aleukemic presentation of large granular lymphocytic leukemia: a case report

Bagacean C, Tempescul A, Patiu M, Fetica B, Bumbea H, Zdrenghea M

OncoTargets and Therapy 2017, 10:31-34

Published Date: 19 December 2016

Review

Potential role of immunotherapy in advanced non-small-cell lung cancer

de Mello RA, Veloso AF, Esrom Catarina P, Nadine S, Antoniou G

OncoTargets and Therapy 2017, 10:21-30

Published Date: 16 December 2016

Original Research

J-pouch versus Roux-en-Y reconstruction after gastrectomy: functional assessment and quality of life (randomized trial)

Zonca P, Maly T, Ihnat P, Peteja M, Kraft O, Kuca K

OncoTargets and Therapy 2017, 10:13-19

Published Date: 16 December 2016

Original Research

Association between TLR-9 polymorphisms and colon cancer susceptibility in Saudi Arabian female patients

Semlali A, Parine NR, Al Amri A, Azzi A, Arafah M, Kohailan M, Shaik JP, Almadi MA, Aljebreen AM, Alharbi O, Ali Azzam N, Rouabhia M, Alanazi MS

OncoTargets and Therapy 2017, 10:1-11

Published Date: 16 December 2016

Review

Non-secretory multiple myeloma: from biology to clinical management

Dupuis MM, Tuchman SA

OncoTargets and Therapy 2016, 9:7583-7590

Published Date: 15 December 2016

Review

Sunitinib in the treatment of gastrointestinal stromal tumor: patient selection and perspectives

Mulet-Margalef N, Garcia-del-Muro X

OncoTargets and Therapy 2016, 9:7573-7582

Published Date: 15 December 2016

Original Research

Lipopolysaccharide-induced α-catenin downregulation enhances the motility of human colorectal cancer cells in an NF-κB signaling-dependent manner

Cheng G, Yang S, Zhang G, Xu Y, Liu X, Sun W, Zhu L

OncoTargets and Therapy 2016, 9:7563-7571

Published Date: 14 December 2016

Original Research

Evaluation of the efficacy of chemoradiotherapy in cervical cancer using diffusion-weighted imaging and apparent diffusion coefficient

Ju F

OncoTargets and Therapy 2016, 9:7555-7561

Published Date: 13 December 2016

Original Research

Different levels of serum microRNAs in prostate cancer and benign prostatic hyperplasia: evaluation of potential diagnostic and prognostic role

Cochetti G, Poli G, Guelfi G, Boni A, Egidi MG, Mearini E

OncoTargets and Therapy 2016, 9:7545-7553

Published Date: 13 December 2016

Original Research

The benefit of using bladder sub-volume equivalent uniform dose constraints in prostate intensity-modulated radiotherapy planning

Zhu J, Simon A, Haigron P, Lafond C, Acosta O, Shu H, Castelli J, Li B, De Crevoisier R

OncoTargets and Therapy 2016, 9:7537-7544

Published Date: 12 December 2016

Original Research

A pilot study employing hepatic intra-arterial irinotecan injection of drug-eluting beads as salvage therapy in liver metastatic colorectal cancer patients without extrahepatic involvement: the first southern Italy experience

Ranieri G, Niccoli Asabella A, Altini C, Fazio V, Caporusso L, Marech I, Vinciarelli G, Macina F, de Ceglia D, Fanelli M, Ammendola M, Rubini G, Gadaleta CD

OncoTargets and Therapy 2016, 9:7527-7535

Published Date: 12 December 2016

Original Research

β-Elemene treatment of glioblastoma: a single-center retrospective study

Ma C, Zhou W, Yan Z, Qu M, Bu X

OncoTargets and Therapy 2016, 9:7521-7526

Published Date: 12 December 2016

Original Research

Correlation between epidermal growth factor receptor tyrosine kinase inhibitor efficacy and circulating tumor cell levels in patients with advanced non-small cell lung cancer

He W, Li W, Jiang B, Chang L, Jin C, Tu C, Li Y

OncoTargets and Therapy 2016, 9:7515-7520

Published Date: 12 December 2016

Original Research

Early detection of poor outcome in patients with metastatic colorectal cancer: tumor kinetics evaluated by circulating tumor cells

Souza e Silva V, Chinen LTD, Abdallah EA, Damascena A, Paludo J, Chojniak R, Dettino ALA, Mello CAL, Alves VS, Fanelli MF

OncoTargets and Therapy 2016, 9:7503-7513

Published Date: 13 December 2016

Original Research

Overexpression and clinical significance of MYC-associated zinc finger protein in pancreatic carcinoma

Zhu X, Luo W, Liang W, Tang F, Bei C, Ren Y, Qin L, Tan C, Zhang Y, Tan S

OncoTargets and Therapy 2016, 9:7493-7501

Published Date: 12 December 2016

Original Research

Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells

Ye T, Su J, Huang C, Yu D, Dai S, Huang X, Chen B, Zhou M

OncoTargets and Therapy 2016, 9:7481-7492

Published Date: 12 December 2016

Review

Biomarkers in pancreatic adenocarcinoma: current perspectives

Swords DS, Firpo MA, Scaife CL, Mulvihill SJ

OncoTargets and Therapy 2016, 9:7459-7467

Published Date: 9 December 2016

Original Research

Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion in colorectal cancer

Guo J, Li J, Zhu C, Feng W, Shao J, Wan L, Huang M, He J

OncoTargets and Therapy 2016, 9:7451-7458

Published Date: 9 December 2016

Original Research

Comparison of the clinical features and hematopoietic stem cell transplantation outcomes of mediastinal malignant germ cell tumors with nonmediastinal extragonadal placements

Ocal N, Yildiz B, Karadurmus N, Dogan D, Ozaydin S, Ocal R, Ozturk M, Arpaci F, Bilgic H

OncoTargets and Therapy 2016, 9:7445-7450

Published Date: 9 December 2016

Original Research

Omega-3 polyunsaturated fatty acids in the prevention of postoperative complications in colorectal cancer: a meta-analysis

Xie H, Chang Y

OncoTargets and Therapy 2016, 9:7435-7443

Published Date: 9 December 2016

Original Research

Prognostic value of p53 mutation for poor outcome of Asian primary liver cancer patients: evidence from a cohort study and meta-analysis of 988 patients

Wen X, Lu F, Liu S

OncoTargets and Therapy 2016, 9:7425-7433

Published Date: 8 December 2016

Original Research

Prediction of biological behavior and prognosis of colorectal cancer patients by tumor MSI/MMR in the Chinese population

Yan WY, Hu J, Xie L, Cheng L, Yang M, Li L, Shi J, Liu BR, Qian X

OncoTargets and Therapy 2016, 9:7415-7424

Published Date: 8 December 2016

Original Research

Association between CHFR gene hypermethylation and gastric cancer risk: a meta-analysis

Shi H, Wang X, Wang J, Pan J, Liu J, Ye B

OncoTargets and Therapy 2016, 9:7409-7414

Published Date: 8 December 2016

Original Research

Identification of feature genes for smoking-related lung adenocarcinoma based on gene expression profile data

Liu Y, Ni R, Zhang H, Miao L, Wang J, Jia W, Wang Y

OncoTargets and Therapy 2016, 9:7397-7407

Published Date: 7 December 2016

Original Research

Association between proto-oncogene mutations and clinicopathologic characteristics and overall survival in colorectal cancer in East Azerbaijan, Iran

Dolatkhah R, Somi MH, Asvadi Kermani I, Bonyadi M, Sepehri B, Boostani K, Azadbakht S, Fotouhi N, Farassati F, Dastgiri S

OncoTargets and Therapy 2016, 9:7385-7395

Published Date: 7 December 2016

Original Research

Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway

Kang Y, Hu W, Bai E, Zheng H, Liu Z, Wu J, Jin R, Zhao C, Liang G

OncoTargets and Therapy 2016, 9:7373-7384

Published Date: 5 December 2016

Original Research

Mutations in hepatitis B virus small S genes predict postoperative survival in hepatocellular carcinoma

Peng L, Yang G, Wu C, Wang WS, Wu J, Guo Z

OncoTargets and Therapy 2016, 9:7367-7372

Published Date: 2 December 2016

Review

Next-generation sequencing: advances and applications in cancer diagnosis

Serratì S, De Summa S, Pilato B, Petriella D, Lacalamita R, Tommasi S, Pinto R

OncoTargets and Therapy 2016, 9:7355-7365

Published Date: 2 December 2016

Original Research

Structure–activity relationships study of mTOR kinase inhibition using QSAR and structure-based drug design approaches

Lakhlili W, Yasri A, Ibrahimi A

OncoTargets and Therapy 2016, 9:7345-7353

Published Date: 2 December 2016

Review

History and progression of Fat cadherins in health and disease

Zhang X, Liu J, Liang X, Chen J, Hong J, Li L, He Q, Cai X

OncoTargets and Therapy 2016, 9:7337-7343

Published Date: 1 December 2016

Original Research

Postoperative adjuvant chemotherapy combined with intracavitary brachytherapy in early-stage cervical cancer patients with intermediate risk factors

Yu H, Zhang LL, Du X, Sheng XG

OncoTargets and Therapy 2016, 9:7331-7335

Published Date: 1 December 2016

Original Research

Mesoporous silica nanoparticles functionalized with folic acid/methionine for active targeted delivery of docetaxel

Khosravian P, Shafiee Ardestani M, Khoobi M, Ostad SN, Dorkoosh FA, Akbari Javar H, Amanlou M

OncoTargets and Therapy 2016, 9:7315-7330

Published Date: 1 December 2016

Original Research

Long-term benefit of sunitinib in patients with metastatic renal cell carcinoma in Latin America: retrospective analysis of patient clinical characteristics

Smaletz O, Chacón M, de Oliveira Koch L, de Carvalho Rocha DR, Cardoso FC

OncoTargets and Therapy 2016, 9:7309-7314

Published Date: 30 November 2016

Original Research

Silencing of miR-1247 by DNA methylation promoted non-small-cell lung cancer cell invasion and migration by effects of STMN1

Zhang J, Fu J, Pan Y, Zhang X, Shen L

OncoTargets and Therapy 2016, 9:7297-7307

Published Date: 1 December 2016

Original Research

CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer

Yang K, Gao K, Hu G, Wen Y, Lin C, Li X

OncoTargets and Therapy 2016, 9:7285-7295

Published Date: 30 November 2016

Original Research

A randomized Phase II trial of the tumor vascular disrupting agent CA4P (fosbretabulin tromethamine) with carboplatin, paclitaxel, and bevacizumab in advanced nonsquamous non-small-cell lung cancer

Garon EB, Neidhart JD, Gabrail NY, de Oliveira MR, Balkissoon J, Kabbinavar F

OncoTargets and Therapy 2016, 9:7275-7283

Published Date: 30 November 2016

Review

Androgen deprivation therapy as backbone therapy in the management of prostate cancer

Merseburger AS, Alcaraz A, von Klot CA

OncoTargets and Therapy 2016, 9:7263-7274

Published Date: 29 November 2016

Original Research

Let-7a enhances the sensitivity of hepatocellular carcinoma cells to cetuximab by regulating STAT3 expression

Xue F, Liu YH, Zhang HW, Wen Y, Yan L, Tang Q, Xiao EH, Zhang DY

OncoTargets and Therapy 2016, 9:7253-7261

Published Date: 28 November 2016

Review

The evolution of the diminishing role of extrapleural pneumonectomy in the surgical management of malignant pleural mesothelioma

Azzouqa AG, Stevenson JP

OncoTargets and Therapy 2016, 9:7247-7252

Published Date: 25 November 2016

Review

Trastuzumab in the management of gastroesophageal cancer: patient selection and perspectives

Davidson M, Starling N

OncoTargets and Therapy 2016, 9:7235-7245

Published Date: 25 November 2016

Original Research

Comparison of survival rates between 3D conformal radiotherapy and intensity-modulated radiotherapy in patients with stage Ⅲ non–small cell lung cancer

Kong M, Hong SE

OncoTargets and Therapy 2016, 9:7227-7234

Published Date: 24 November 2016

Original Research

E2A-PBX1 exhibited a promising prognosis in pediatric acute lymphoblastic leukemia treated with the CCLG-ALL2008 protocol

Hu YX, He HL, Lu J, Wang Y, Xiao PF, Li JQ, Li J, Sun YN, Lv H, Fan JJ, Yao YH, Chai YH, Hu SY

OncoTargets and Therapy 2016, 9:7219-7225

Published Date: 22 November 2016

Original Research

Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time

Baek N, Seo OW, Kim M, Hulme J, An SSA

OncoTargets and Therapy 2016, 9:7207-7218

Published Date: 22 November 2016

Original Research

High expression of HMGA2 predicts poor survival in patients with clear cell renal cell carcinoma

Na N, Si T, Huang Z, Miao B, Hong L, Li H, Qiu J, Qiu J

OncoTargets and Therapy 2016, 9:7199-7205

Published Date: 22 November 2016

Original Research

Effect of smoking on the genetic makeup of toll-like receptors 2 and 6

Kohailan M, Alanazi M, Rouabhia M, Alamri A, Parine NR, Alhadheq A, Basavarajappa S, Abdullah Al-Kheraif AA, Semlali A

OncoTargets and Therapy 2016, 9:7187-7198

Published Date: 21 November 2016

Original Research

The prognostic value of systemic and local inﬂammation in patients with laryngeal squamous cell carcinoma

Wang J, Wang SZ, Song XM, Zeng WJ, Wang SY, Chen F, Ding H

OncoTargets and Therapy 2016, 9:7177-7185

Published Date: 21 November 2016

Original Research

Effect of CyberKnife stereotactic body radiation therapy for hepatocellular carcinoma on hepatic toxicity

Liang P, Huang C, Liang S, Li Y, Huang S, Lian Z, Liu J, Tang Y, Lu H

OncoTargets and Therapy 2016, 9:7169-7175

Published Date: 18 November 2016

Original Research

Next-generation sequence detects ARAP3 as a novel oncogene in papillary thyroid carcinoma

Wang QX, Chen ED, Cai YF, Zhou YL, Zheng ZC, Wang YH, Jin YX, Jin WX, Zhang XH, Wang OC

OncoTargets and Therapy 2016, 9:7161-7167

Published Date: 18 November 2016

Review

BRAF inhibitors and radiotherapy for melanoma brain metastases: potential advantages and disadvantages of combination therapy

Chowdhary M, Patel KR, Danish HH, Lawson DH, Khan MK

OncoTargets and Therapy 2016, 9:7149-7159

Published Date: 12 December 2016

Original Research

Efficacy of three-dimensional conformal radiotherapy combined with transarterial chemoembolization for hepatocellular carcinoma with portal vein tumor thrombus

Wu F, Lu H, Zhu S, Li Z, Zou L, Bai T, Chen J, Yang T, Liang S

OncoTargets and Therapy 2016, 9:7141-7147

Published Date: 1 December 2016

Original Research

Meta-analysis of the impact of thioprine S-methyltransferase polymorphisms on the tolerable 6-mercaptopurine dose considering initial dose and ethnic difference

Kim MG, Ko M, Kim IW, Oh JM

OncoTargets and Therapy 2016, 9:7133-7139

Published Date: 18 November 2016

Original Research

Deferred radiotherapy and upfront procarbazine–ACNU–vincristine administration for 1p19q codeleted oligodendroglial tumors are associated with favorable outcome without compromising patient performance, regardless of WHO grade

Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Suzuki SO, Iwaki T, Shono T, Mizoguchi M, Iihara K

OncoTargets and Therapy 2016, 9:7123-7131

Published Date: 17 November 2016

Original Research

Methotrexate induces DNA damage and inhibits homologous recombination repair in choriocarcinoma cells

Xie L, Zhao T, Cai J, Su Y, Wang Z, Dong W

OncoTargets and Therapy 2016, 9:7115-7122

Published Date: 17 November 2016

Original Research

Human papillomavirus as a potential risk factor for gastric cancer: a meta-analysis of 1,917 cases

Zeng ZM, Luo FF, Zou LX, He RQ, Pan DH, Chen X, Xie TT, Li YQ, Peng ZG, Chen G

OncoTargets and Therapy 2016, 9:7105-7114

Published Date: 17 November 2016

Methodology

A FISH-based method for assessment of HER-2 amplification status in breast cancer circulating tumor cells following CellSearch isolation

Frithiof H, Aaltonen K, Ryden L

OncoTargets and Therapy 2016, 9:7095-7103

Published Date: 16 November 2016

Original Research

Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the Phase III OPTiM trial

Harrington KJ, Andtbacka RHI, Collichio F, Downey G, Chen L, Szabo Z, Kaufman HL

OncoTargets and Therapy 2016, 9:7081-7093

Published Date: 16 November 2016

Original Research

Lrig1 is a positive prognostic marker in hepatocellular carcinoma

Yang B, Dai C, Tan RM, Zhang B, Meng X, Ye J, Wang XQ, Wei L, He F, Chen ZS

OncoTargets and Therapy 2016, 9:7071-7079

Published Date: 15 November 2016

Original Research

Meta-analysis of outcomes of patients with stage IV colorectal cancer managed with chemotherapy/radiochemotherapy with and without primary tumor resection

Lee KC, Ou YC, Hu WH, Liu CC, Chen HH

OncoTargets and Therapy 2016, 9:7059-7069

Published Date: 15 November 2016

Original Research

MicroRNA-9 suppresses the growth, migration, and invasion of malignant melanoma cells via targeting NRP1

Xu D, Chen XF, He QY, Luo CQ

OncoTargets and Therapy 2016, 9:7047-7057

Published Date: 15 November 2016

Original Research

Identification of lncRNA FAM83H-AS1 as a novel prognostic marker in luminal subtype breast cancer

Yang F, Lv S, Lv L, Liu Y, Dong S, Yao Z, Dai X, Zhang X, Wang O

OncoTargets and Therapy 2016, 9:7039-7045

Published Date: 15 November 2016

Original Research

Predictive values of diffusion-weighted imaging and perfusion-weighted imaging in evaluating the efficacy of transcatheter arterial chemoembolization for hepatocellular carcinoma

Lin M, Tian MM, Zhang WP, Xu L, Jin P

OncoTargets and Therapy 2016, 9:7029-7037

Published Date: 14 November 2016

Clinical Trial Report

ERCC1 and XRCC1 but not XPA single nucleotide polymorphisms correlate with response to chemotherapy in endometrial carcinoma

Chen L, Liu MM, Liu H, Lu D, Zhao XD, Yang XJ

OncoTargets and Therapy 2016, 9:7019-7028

Published Date: 14 November 2016

Original Research

CT-diagnosed severe skull base bone destruction predicts distant bone metastasis in early N-stage nasopharyngeal carcinoma

Yi W, Liu ZG, Li X, Tang J, Jiang CB, Hu JY, Tu ZW, Wang H, Niu DL, Xia YF

OncoTargets and Therapy 2016, 9:7011-7017

Published Date: 14 November 2016

Original Research

MicroRNA-29a plays a suppressive role in non-small cell lung cancer cells via targeting LASP1

Hu ZL, Cui YH, Zhou YH, Zhou KY, Qiao XQ, Li CQ, Wang S

OncoTargets and Therapy 2016, 9:6999-7009

Published Date: 14 November 2016

Original Research

The relationship between the expression of USP22, BMI1, and EZH2 in hepatocellular carcinoma and their impacts on prognosis

Zhai R, Tang F, Gong JH, Zhang J, Lei B, Li B, Wei YC, Liang XS, Tang B, He SQ

OncoTargets and Therapy 2016, 9:6987-6998

Published Date: 24 November 2016

Original Research

Role of p14ARF and p15INK4B promoter methylation in patients with lung cancer: a systematic meta-analysis

Yang X, Yang L, Dai W, Ye B

OncoTargets and Therapy 2016, 9:6977-6985

Published Date: 11 November 2016

Original Research

Association of telomerase reverse transcriptase promoter mutations with clinicopathological features and prognosis of thyroid cancer: a meta-analysis

Su X, Jiang X, Wang W, Wang H, Xu X, Lin A, Teng X, Wu H, Teng L

OncoTargets and Therapy 2016, 9:6965-6976

Published Date: 11 November 2016

Original Research

Portulacerebroside A inhibits adhesion, migration, and invasion of human leukemia HL60 cells and U937 cells through the regulation of p38/JNK signaling pathway

Ye QD, Liao XL, Fu P, Dou JY, Chen K, Jiang H

OncoTargets and Therapy 2016, 9:6953-6963

Published Date: 11 November 2016

Original Research

Comparison of internal target volumes defined on 3-dimensional, 4-dimensonal, and cone-beam CT images of non-small-cell lung cancer

Li F, Li J, Ma Z, Zhang Y, Xing J, Qi H, Shang D

OncoTargets and Therapy 2016, 9:6945-6951

Published Date: 17 November 2016

Original Research

Paxillin functions as an oncogene in human gliomas by promoting cell migration and invasion

Chen B, Xia L, Xu C, Xiao F, Wang Y

OncoTargets and Therapy 2016, 9:6935-6943

Published Date: 9 November 2016

Original Research

Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Pileczki V, Pop L, Braicu C, Budisan L, Bolba Morar G, del C Monroig-Bosque P, Sandulescu RV, Berindan-Neagoe I

OncoTargets and Therapy 2016, 9:6921-6933

Published Date: 11 November 2016

Original Research

A retrospective analysis of the clinicopathological and molecular characteristics of pulmonary blastoma

Zhao YY, Liu L, Zhou T, Zhou NN, Yang YP, Hou X, Li Y, Zhao HY, Huang Y, Zhang L

OncoTargets and Therapy 2016, 9:6915-6920

Published Date: 8 November 2016

Original Research

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition

Zhang XG, Zhang T, Yang K, Zhang MH, Wang KM

OncoTargets and Therapy 2016, 9:6909-6914

Published Date: 8 November 2016

Original Research

Adefovir dipivoxil is less expensive than lamivudine and associated with similar prognosis in patients with hepatitis B virus-related hepatocellular carcinoma after radical resection

Zhong JH, Ke Y, Zhu SL, Wang L, Luo CP, Gong WF, You XM, Ma L, Xiang BD, Li LQ

OncoTargets and Therapy 2016, 9:6897-6907

Published Date: 10 November 2016

Original Research

Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer

Lee AR, Park J, Jung KJ, Jee SH, Kim-Yoon SJ

OncoTargets and Therapy 2016, 9:6885-6895

Published Date: 7 November 2016

Review

Hürthle cell carcinoma: current perspectives

Ahmadi S, Stang M, Jiang XS, Sosa JA

OncoTargets and Therapy 2016, 9:6873-6884

Published Date: 7 November 2016

Original Research

NOTCH1 is a poor prognostic factor for breast cancer and is associated with breast cancer stem cells

Zhong Y, Shen S, Zhou Y, Mao F, Lin Y, Guan J, Xu Y, Zhang S, Liu X, Sun Q

OncoTargets and Therapy 2016, 9:6865-6871

Published Date: 7 November 2016

Original Research

FAS and FASL genetic polymorphisms impact on clinical outcome of malignant pleural mesothelioma

El-Hamamsy M, Ghali RR, Saad AS, Shaheen SM, Salem AM

OncoTargets and Therapy 2016, 9:6857-6863

Published Date: 7 November 2016

Original Research

Synergistic activity of vorinostat combined with gefitinib but not with sorafenib in mutant KRAS human non-small cell lung cancers and hepatocarcinoma

Jeannot V, Busser B, Vanwonterghem L, Michallet S, Ferroudj S, Cokol M, Coll JL, Ozturk M, Hurbin A

OncoTargets and Therapy 2016, 9:6843-6855

Published Date: 9 November 2016

Original Research

Benefit of percutaneous endoscopic gastrostomy in patients undergoing definitive chemoradiotherapy for locally advanced nasopharyngeal carcinoma

Xu Y, Guo Q, Lin J, Chen B, Wen J, Lu T, Xu Y, Zhang M, Pan J, Lin S

OncoTargets and Therapy 2016, 9:6835-6841

Published Date: 4 November 2016

Original Research

Local recurrence following mastectomy and autologous breast reconstruction: incidence, risk factors, and management

Wu S, Mo M, Wang Y, Zhang N, Li J, Di G, Shao Z, Wu J, Liu G

OncoTargets and Therapy 2016, 9:6829-6834

Published Date: 4 November 2016

Original Research

Diagnosis reliability of combined flexible sigmoidoscopy and fecal-immunochemical test in colorectal neoplasia screening

Iovanescu D, Frandes M, Lungeanu D, Burlea A, Miutescu BP, Miutescu E

OncoTargets and Therapy 2016, 9:6819-6828

Published Date: 4 November 2016

Original Research

Differentiation between adrenal adenomas and nonadenomas using dynamic contrast-enhanced computed tomography

Wang XF, Li KG, Sun HR, Zhao JL, Zheng LF, Zhang ZL, Bai RJ, Zhang GX

OncoTargets and Therapy 2016, 9:6809-6817

Published Date: 3 November 2016

Original Research

Association of TIMP-2-418G/C and TIMP-2-303G/A with gastric cancer: a meta-analysis

Yang Y, Xiong Y, Li J, Wu C, Jiang J

OncoTargets and Therapy 2016, 9:6801-6808

Published Date: 3 November 2016

Original Research

Total versus subtotal gastrectomy for distal gastric cancer: meta-analysis of randomized clinical trials

Kong L, Yang N, Shi L, Zhao G, Wang M, Zhang Y

OncoTargets and Therapy 2016, 9:6795-6800

Published Date: 7 November 2016

Original Research

Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking

Coppola C, Riccio G, Barbieri A, Monti MG, Piscopo G, Rea D, Arra C, Maurea C, De Lorenzo C, Maurea N

OncoTargets and Therapy 2016, 9:6785-6794

Published Date: 2 November 2016

Original Research

Cervical nodal necrosis is an independent survival predictor in nasopharyngeal carcinoma: an observational cohort study

Luo Y, Ren J, Zhou P, Gao Y, Yang G, Lang J

OncoTargets and Therapy 2016, 9:6775-6783

Published Date: 1 November 2016

Original Research

The association, clinicopathological significance, and diagnostic value of CDH1 promoter methylation in head and neck squamous cell carcinoma: a meta-analysis of 23 studies

Shen ZS, Zhou CC, Li JY, Deng HX, Li Q, Wang J

OncoTargets and Therapy 2016, 9:6763-6773

Published Date: 31 October 2016

Original Research

Minimally invasive esophagectomy versus open esophagectomy for esophageal cancer: a meta-analysis

Lv L, Hu WD, Ren YC, Wei XX

OncoTargets and Therapy 2016, 9:6751-6762

Published Date: 31 October 2016

Original Research

Positive expression of KIF20A indicates poor prognosis of glioma patients

Duan J, Huang W, Shi H

OncoTargets and Therapy 2016, 9:6741-6749

Published Date: 2 November 2016

Review

A current perspective on stereotactic body radiation therapy for pancreatic cancer

Hong JC, Czito BG, Willett CG, Palta M

OncoTargets and Therapy 2016, 9:6733-6739

Published Date: 31 October 2016

Original Research

Effect of VEGF-C siRNA and endostatin on ring formation and proliferation of esophageal squamous cell carcinoma lymphatic endothelial cells

Zheng YP, Sun MM, Chen JY, He LL, Zhao N, Chen KS

OncoTargets and Therapy 2016, 9:6727-6732

Published Date: 31 October 2016

Original Research

High expression of muscarinic acetylcholine receptor 3 predicts poor prognosis in patients with pancreatic ductal adenocarcinoma

Zhang L, Xiu DR, Zhan J, He XK, Guo LM, Wang JL, Tao M, Fu W, Zhang HQ

OncoTargets and Therapy 2016, 9:6719-6726

Published Date: 31 October 2016

Original Research

Elevated HABP1 protein expression correlates with progression and poor survival in patients with gastric cancer

Gao H, Yao Q, Lan X, Li S, Wu J, Zeng G, Xue Y

OncoTargets and Therapy 2016, 9:6711-6718

Published Date: 31 October 2016

Original Research

Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis

Chen Z, Shao Y, Wang K, Cao W, Xiong Y, Wu R, Luo S, Xu X, He X

OncoTargets and Therapy 2016, 9:6701-6710

Published Date: 28 October 2016

Original Research

Efficacy and toxicities of adding molecular targeted agents to first-line chemotherapy in the treatment of advanced biliary tract cancer: a systematic review and meta-analysis

Zhao S, Miao Y, Wang R, Guo H, Jin F, Guo X, Luo T

OncoTargets and Therapy 2016, 9:6695-6700

Published Date: 28 October 2016

Original Research

Biosimilar epoetin for the management of chemotherapy-induced anemia in elderly patients

Kurtz JE, Soubeyran P, Michallet M, Luporsi E, Albrand H

OncoTargets and Therapy 2016, 9:6689-6693

Published Date: 28 October 2016

Original Research

Association between prognostic survival of human colorectal carcinoma and ZNRF3 expression

Yu N, Zhu H, Tao Y, Huang Y, Song X, Zhou Y, Li Y, Pei Q, Tan Q, Pei H

OncoTargets and Therapy 2016, 9:6679-6687

Published Date: 28 October 2016

Original Research

Dendritic cell immunotherapy versus bevacizumab plus irinotecan in recurrent malignant glioma patients: a survival gain analysis

Artene S, Turcu-Stiolica A, Hartley R, Ciurea ME, Daianu O, Brindusa C, Alexandru O, Tataranu LG, Purcaru SO, Dricu A

OncoTargets and Therapy 2016, 9:6669-6677

Published Date: 4 November 2016

Original Research

SPARC is a possible predictive marker for albumin-bound paclitaxel in non-small-cell lung cancer

Komiya K, Nakamura T, Nakashima C, Takahashi K, Umeguchi H, Watanabe N, Sato A, Takeda Y, Kimura S, Sueoka-Aragane N

OncoTargets and Therapy 2016, 9:6663-6668

Published Date: 27 October 2016

Original Research

The medicinal fungus Antrodia cinnamomea regulates DNA repair and enhances the radiosensitivity of human esophageal cancer cells

Liu YM, Liu YK, Wang LW, Huang YC, Huang PI, Tsai TH, Chen YJ

OncoTargets and Therapy 2016, 9:6651-6661

Published Date: 27 October 2016

Original Research

Investigation of cyclin D1 rs9344 G>A polymorphism in colorectal cancer: a meta-analysis involving 13,642 subjects

Qiu H, Cheng C, Wang Y, Kang M, Tang W, Chen S, Gu H, Liu C, Chen Y

OncoTargets and Therapy 2016, 9:6641-6650

Published Date: 27 October 2016

Original Research

MLL1 promotes cervical carcinoma cell tumorigenesis and metastasis through interaction with β-catenin

Qiang R, Cai N, Wang X, Wang L, Cui K, Wang X, Li X

OncoTargets and Therapy 2016, 9:6631-6640

Published Date: 28 October 2016

Original Research

BCL3 exerts an oncogenic function by regulating STAT3 in human cervical cancer

Zhao H, Wang WL, Zhao QH, Hu GM, Deng KH, Liu YL

OncoTargets and Therapy 2016, 9:6619-6629

Published Date: 26 October 2016

Original Research

Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction

Jiang C, Jin S, Jiang Z, Wang J

OncoTargets and Therapy 2016, 9:6609-6618

Published Date: 26 October 2016

Case report

Effective treatment with icotinib in lung adenocarcinoma with EGFR and ALK co-alterations and brain metastasis

Ye CY, Wang J, Zheng S, Chai Y

OncoTargets and Therapy 2016, 9:6605-6608

Published Date: 26 October 2016

Original Research

miR-497 suppresses epithelial–mesenchymal transition and metastasis in colorectal cancer cells by targeting fos-related antigen-1

Zhang N, Shen Q, Zhang P

OncoTargets and Therapy 2016, 9:6597-6604

Published Date: 25 October 2016

Original Research

The accumulation of macrophages attenuates the effect of recombinant human endostatin on lung cancer

Liu YY, Tu L, Wang L, Long J, Wang J, Wang Y, Luo F, Cao D

OncoTargets and Therapy 2016, 9:6581-6595

Published Date: 25 October 2016

Original Research

Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease

Hua J, Ding T, Yang L

OncoTargets and Therapy 2016, 9:6573-6579

Published Date: 25 October 2016

Original Research

Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study

Cai CF, Sun JY, He Z, Lin HX, Liu FR, Wang Y

OncoTargets and Therapy 2016, 9:6569-6572

Published Date: 25 October 2016

Original Research

Patterns of failure and survival in patients with nasopharyngeal carcinoma treated with intensity-modulated radiation therapy in Saudi Arabia

Maklad AM, Bayoumi Y, Senosy Hassan MA, Elawadi AA, AlHussain H, Elyamany A, Aldhahri SF, Al-Qahtani KH, AlQahtani M, Tunio MA

OncoTargets and Therapy 2016, 9:6561-6567

Published Date: 25 October 2016

Review

Cell-free DNA as a diagnostic marker for cancer: current insights

Salvi S, Gurioli G, De Giorgi U, Conteduca V, Tedaldi G, Calistri D, Casadio V

OncoTargets and Therapy 2016, 9:6549-6559

Published Date: 25 October 2016

Original Research

WISP-1 overexpression upregulates cell proliferation in human salivary gland carcinomas via regulating MMP-2 expression

Li FJ, Wang XJ, Zhou XL

OncoTargets and Therapy 2016, 9:6539-6548

Published Date: 21 October 2016

Original Research

The postoperative neutrophil-to-lymphocyte ratio and changes in this ratio predict survival after the complete resection of stage I non-small cell lung cancer

Jin F, Han A, Shi F, Kong L, Yu J

OncoTargets and Therapy 2016, 9:6529-6537

Published Date: 21 October 2016

Review

Novel therapeutic strategies for patients with triple-negative breast cancer

Zhang JF, Liu J, Wang Y, Zhang B

OncoTargets and Therapy 2016, 9:6519-6528

Published Date: 21 October 2016

Original Research

High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells

Chen X, Zhang Q, Luo Y, Gao C, Zhuang X, Xu G, Qaio T

OncoTargets and Therapy 2016, 9:6511-6518

Published Date: 21 October 2016

Original Research

The diagnostic value of 99TcM-2-(2-methyl-5-nitro-1H-imidazol-1-yl) ethyl dihydrogen phosphate hypoxia imaging and its evaluation performance for radiotherapy efficacy in non-small-cell lung cancer

Yang Y, Han G, Xu W

OncoTargets and Therapy 2016, 9:6499-6509

Published Date: 21 October 2016

Original Research

Snake venom causes apoptosis by increasing the reactive oxygen species in colorectal and breast cancer cell lines

Al-Asmari AK, Riyasdeen A, Al-Shahrani MH, Islam M

OncoTargets and Therapy 2016, 9:6485-6498

Published Date: 20 October 2016

Original Research

The EGFR tyrosine kinase inhibitors as second-line therapy for EGFR wild-type non-small-cell lung cancer: a real-world study in People's Republic of China

Xu J, Ding G, Zhang X, Jin B, Lou Y, Zhang Y, Wang H, Wu D, Han B

OncoTargets and Therapy 2016, 9:6479-6484

Published Date: 20 October 2016

Review

Lenvatinib and other tyrosine kinase inhibitors for the treatment of radioiodine refractory, advanced, and progressive thyroid cancer

Lorusso L, Pieruzzi L, Biagini A, Sabini E, Valerio L, Giani C, Passannanti P, Pontillo-Contillo B, Battaglia V, Mazzeo S, Molinaro E, Elisei R

OncoTargets and Therapy 2016, 9:6467-6477

Published Date: 20 October 2016

Original Research

Dephosphorylated cofilin expression is associated with poor prognosis in cases of human breast cancer: a tissue microarray analysis

Maimaiti Y, Liu ZM, Tan J, Abudureyimu K, Huang BX, Liu CP, Guo YW, Wang CW, Nie X, Zhou J, Huang T

OncoTargets and Therapy 2016, 9:6461-6466

Published Date: 19 October 2016

Original Research

Inhibitory effect of quercetin on epithelial to mesenchymal transition in SK-MEL-28 human melanoma cells defined by in vitro analysis on 3D collagen gels

Patel DH, Sharma N

OncoTargets and Therapy 2016, 9:6445-6459

Published Date: 19 October 2016

Original Research

Differences in esophageal cancer characteristics and survival between Chinese and Caucasian patients in the SEER database

Lin MQ, Li YP, Wu SG, Sun JY, Lin HX, Zhang SY, He ZY

OncoTargets and Therapy 2016, 9:6435-6444

Published Date: 19 October 2016

Original Research

Intravoxel incoherent motion model–based analysis of diffusion-weighted magnetic resonance imaging with 3 b-values for response assessment in locoregional therapy of hepatocellular carcinoma

Mürtz P, Penner AH, Pfeiffer AK, Sprinkart AM, Pieper CC, König R, Block W, Schild HH, Willinek WA, Kukuk GM

OncoTargets and Therapy 2016, 9:6425-6433

Published Date: 19 October 2016

Original Research

Prognostic nutritional index serves as a predicative marker of survival and associates with systemic inflammatory response in metastatic intrahepatic cholangiocarcinoma

Zhang C, Wang H, Ning Z, Xu L, Zhuang L, Wang P, Meng Z

OncoTargets and Therapy 2016, 9:6417-6423

Published Date: 19 October 2016

Original Research

Double-edged role of G protein-coupled estrogen receptor 1 in breast cancer prognosis: an analysis of 167 breast cancer samples and online data sets

Yang F, Shao ZM

OncoTargets and Therapy 2016, 9:6407-6415

Published Date: 25 October 2016

Original Research

Biomarker and competing endogenous RNA potential of tumor-specific long noncoding RNA in chromophobe renal cell carcinoma

He HT, Xu M, Kuang Y, Han XY, Wang MQ, Yang Q

OncoTargets and Therapy 2016, 9:6399-6406

Published Date: 18 October 2016

Original Research

Prognostic impact of body mass index stratified by smoking status in patients with esophageal squamous cell carcinoma

Sun P, Zhang F, Chen C, Ren C, Bi XW, Yang H, An X, Wang FH, Jiang WQ

OncoTargets and Therapy 2016, 9:6389-6397

Published Date: 17 October 2016

Original Research

Synergistic suppression effect on tumor growth of ovarian cancer by combining cisplatin with a manganese superoxide dismutase-armed oncolytic adenovirus

Wang S, Shu J, Chen L, Chen X, Zhao J, Li S, Mou X, Tong X

OncoTargets and Therapy 2016, 9:6381-6388

Published Date: 17 October 2016

Retraction

miR-32 functions as a tumor suppressor and directly targets SOX9 in human non–small cell lung cancer [Retraction]

Zhu D, Chen H, Yang X, Chen W, Wang L, Xu J, Yu L

OncoTargets and Therapy 2016, 9:6379-6380

Published Date: 20 October 2016

Retraction

MiR-206 functions as a tumor suppressor and directly targets K-Ras in human oral squamous cell carcinoma [Retraction]

Lin FO, Yao LJ, Xiao J, Liu DF, Ni ZY

OncoTargets and Therapy 2016, 9:6377-6378

Published Date: 20 October 2016

Review

Personalized treatment in advanced ALK-positive non-small cell lung cancer: from bench to clinical practice

Passaro A, Lazzari C, Karachaliou N, Spitaleri G, Pochesci A, Catania C, Rosell R, de Marinis F

OncoTargets and Therapy 2016, 9:6361-6376

Published Date: 17 October 2016

Hypothesis

Cancer: fundamentals behind pH targeting and the double-edged approach

Koltai T

OncoTargets and Therapy 2016, 9:6343-6360

Published Date: 17 October 2016

Original Research

Rare frequency of gene variation and survival analysis in thymic epithelial tumors

Song Z, Yu X, Zhang Y

OncoTargets and Therapy 2016, 9:6337-6342

Published Date: 14 October 2016

Case report

Alveolar rhabdomyosarcoma of the sphenoid sinus mimicking optic neuritis presenting with intermittent visual loss in an adult

Liu W, Jiang L, Jin Y, Yang BT, Lai TYY

OncoTargets and Therapy 2016, 9:6333-6336

Published Date: 14 October 2016

Original Research

hERG1 positivity and Glut-1 negativity identifies high-risk TNM stage I and II colorectal cancer patients, regardless of adjuvant chemotherapy

Muratori L, Petroni G, Antonuzzo L, Boni L, Iorio J, Lastraioli E, Bartoli G, Messerini L, Di Costanzo F, Arcangeli A

OncoTargets and Therapy 2016, 9:6325-6332

Published Date: 14 October 2016

Original Research

18F-fludrodeoxyglucose maximal standardized uptake value and metabolic tumor burden are associated with major chemotherapy-related tumor markers in NSCLC patients

Bai L, Guo CH, Wang JS, Liu X, Li Y, Li M, Guo YM, Duan XY

OncoTargets and Therapy 2016, 9:6315-6324

Published Date: 14 October 2016

Original Research

Comparison of the efficacy and tolerability of gefitinib with pemetrexed maintenance after first-line platinum-based doublet chemotherapy in advanced lung adenocarcinoma: single-center experience

Lin L, Zhao J, Hu J, Huang F, Han J, He Y, Cao X

OncoTargets and Therapy 2016, 9:6305-6314

Published Date: 14 October 2016

Review

Prognostic value of endocan expression in cancers: evidence from meta-analysis

Huang X, Chen C, Wang X, Zhang JY, Ren BH, Ma DW, Xia L, Xu XY, Xu L

OncoTargets and Therapy 2016, 9:6297-6304

Published Date: 13 October 2016

Case report

Primary adenoid cystic carcinoma of the trachea with thyroid invasion: a case report and literature review

Qi D, Feng L, Li J, Liu B, Zhang Q

OncoTargets and Therapy 2016, 9:6291-6296

Published Date: 13 October 2016

Original Research

Prognostic value of fever grade combined with neutrophil percentage in hepatocellular carcinoma patients presenting fever as the initial manifestation

Gong ZJ, Guo W, Sun YF, Zhang X, Qiu SJ, Zhou J, Fan J, Yang XR

OncoTargets and Therapy 2016, 9:6281-6290

Published Date: 13 October 2016

Original Research

CT-detected solitary thyroid calcification: an important imaging feature for papillary carcinoma

Yang T, Huang Y, Jing X, Gai X, Li W

OncoTargets and Therapy 2016, 9:6273-6279

Published Date: 13 October 2016

Review

Locally advanced rectal cancer: management challenges

Kokelaar RF, Evans MD, Davies M, Harris DA, Beynon J

OncoTargets and Therapy 2016, 9:6265-6272

Published Date: 13 October 2016

Original Research

Epidermal growth factor receptor and B7-H3 expression in esophageal squamous tissues correlate to patient prognosis

Song J, Shi W, Zhang Y, Sun M, Liang X, Zheng S

OncoTargets and Therapy 2016, 9:6257-6263

Published Date: 12 October 2016

Original Research

miR-144 functions as a tumor suppressor in breast cancer through inhibiting ZEB1/2-mediated epithelial mesenchymal transition process

Pan Y, Zhang J, Fu H, Shen L

OncoTargets and Therapy 2016, 9:6247-6255

Published Date: 11 October 2016

Review

Current classification, treatment options, and new perspectives in the management of adipocytic sarcomas

De Vita A, Mercatali L, Recine F, Pieri F, Riva N, Bongiovanni A, Liverani C, Spadazzi C, Miserocchi G, Amadori D, Ibrahim T

OncoTargets and Therapy 2016, 9:6233-6246

Published Date: 11 October 2016

Original Research

Differential expression of two activating transcription factor 5 isoforms in papillary thyroid carcinoma

Vicari L, La Rosa C, Forte S, Calabrese G, Colarossi C, Aiello E, Salluzzo S, Memeo L

OncoTargets and Therapy 2016, 9:6225-6231

Published Date: 11 October 2016

Original Research

Influence of MDM2 polymorphisms on squamous cell carcinoma susceptibility: a meta-analysis

Yu H, Li H, Zhang J, Liu G

OncoTargets and Therapy 2016, 9:6211-6224

Published Date: 11 October 2016

Original Research

miR-203 facilitates tumor growth and metastasis by targeting fibroblast growth factor 2 in breast cancer

He S, Zhang G, Dong H, Ma M, Sun Q

OncoTargets and Therapy 2016, 9:6203-6210

Published Date: 11 October 2016

Original Research

Everolimus enhances cellular cytotoxicity of lapatinib via the eukaryotic elongation factor-2 kinase pathway in nasopharyngeal carcinoma cells

Liu L, Wang ZH, Han J, Tang C, Chen N, Lin Z, Peng PJ

OncoTargets and Therapy 2016, 9:6195-6201

Published Date: 11 October 2016

Original Research

Sensitivity value of hematological markers in patients receiving chemoradiotherapy for esophageal squamous cell carcinoma

Zhu S, Miao CW, Wang ZT, Peng L, Li B

OncoTargets and Therapy 2016, 9:6187-6193

Published Date: 13 October 2016

Original Research

Biomarker discovery to improve prediction of breast cancer survival: using gene expression profiling, meta-analysis, and tissue validation

Meng L, Xu Y, Xu C, Zhang W

OncoTargets and Therapy 2016, 9:6177-6185

Published Date: 11 October 2016

Case Series

Invasive atypical thymic carcinoid: three case reports and literature review

Zhu S, Wang Z, Liu W, Zong S, Li B

OncoTargets and Therapy 2016, 9:6171-6176

Published Date: 11 October 2016

Clinical Trial Report

The influence of the metastasis pattern of mediastinal lymph nodes on the postoperative radiotherapy’s efficacy for the IIIA-pN2 non-small-cell lung cancer: a retrospective analysis of 220 patients

Zhang B, Zhao L, Yuan Z, Pang Q, Wang P

OncoTargets and Therapy 2016, 9:6161-6169

Published Date: 11 October 2016

Original Research

miR-139-5p regulates proliferation, apoptosis, and cell cycle of uterine leiomyoma cells by targeting TPD52

Chen H, Xu H, Meng YG, Zhang Y, Chen JY, Wei XN

OncoTargets and Therapy 2016, 9:6151-6160

Published Date: 11 October 2016

Original Research

Chemotherapy combined with high-dose extended-field radiotherapy for stage I extranodal nasal-type natural killer/T-cell lymphoma

Luo J, Cao C, Zhu Y, Liu P, Liu L, Lu K, Zhang N, Zhou N

OncoTargets and Therapy 2016, 9:6147-6150

Published Date: 11 October 2016

Original Research

Effectiveness of tyrosine kinase inhibitors on uncommon E709X epidermal growth factor receptor mutations in non-small-cell lung cancer

Wu JY, Shih JY

OncoTargets and Therapy 2016, 9:6137-6145

Published Date: 11 October 2016

Original Research

Prognostic value of microRNA-126 and CRK expression in gastric cancer

Yue S, Shi H, Han J, Zhang T, Zhu W, Zhang D

OncoTargets and Therapy 2016, 9:6127-6135

Published Date: 11 October 2016

Review

Impact of palbociclib combinations on treatment of advanced estrogen receptor-positive/human epidermal growth factor 2-negative breast cancer

Boér K

OncoTargets and Therapy 2016, 9:6119-6125

Published Date: 11 October 2016

Original Research

Association of preoperative levels of selected blood inflammatory markers with prognosis in gliomas

Auezova R, Ryskeldiev N, Doskaliyev A, Kuanyshev Y, Zhetpisbaev B, Aldiyarova N, Ivanova N, Akshulakov S, Auezova L

OncoTargets and Therapy 2016, 9:6111-6117

Published Date: 11 October 2016

Original Research

Downregulation of ALDOB is associated with poor prognosis of patients with gastric cancer

He J, Jin Y, Chen Y, Yao HB, Xia YJ, Ma YY, Wang W, Shao QS

OncoTargets and Therapy 2016, 9:6099-6109

Published Date: 7 October 2016

Original Research

Primary breast diffuse large B-cell lymphoma in the era of rituximab

Zhang N, Cao C, Zhu Y, Liu P, Liu L, Lu K, Luo J, Zhou N

OncoTargets and Therapy 2016, 9:6093-6097

Published Date: 7 October 2016

Original Research

IL-10-1082A/G, -592C/A, and -819T/C polymorphisms in association with lung cancer susceptibility: a meta-analysis

Liu L, Zheng F

OncoTargets and Therapy 2016, 9:6083-6091

Published Date: 7 October 2016

Original Research

Prognostic value of PD-L1 and PD-1 expression in pulmonary neuroendocrine tumors

Fan Y, Ma K, Wang C, Ning J, Hu Y, Dong D, Dong X, Geng Q, Li E, Wu Y

OncoTargets and Therapy 2016, 9:6075-6082

Published Date: 6 October 2016

Review

New developments in the management of non-small-cell lung cancer, focus on rociletinib: what went wrong?

Van Der Steen N, Caparello C, Rolfo C, Pauwels P, Peters GJ, Giovannetti E

OncoTargets and Therapy 2016, 9:6065-6074

Published Date: 6 October 2016

Case report

A patient previously treated with ALK inhibitors for central nervous system lesions from ALK rearranged lung cancer: a case report

Kashima J, Okuma Y, Hishima T

OncoTargets and Therapy 2016, 9:6059-6063

Published Date: 12 October 2016

Original Research

Relationships between MGMT promoter methylation and gastric cancer: a meta-analysis

Yu D, Cao T, Han YD, Huang FS

OncoTargets and Therapy 2016, 9:6049-6057

Published Date: 5 October 2016

Review

Spotlight on elotuzumab in the treatment of multiple myeloma: the evidence to date

Weisel K

OncoTargets and Therapy 2016, 9:6037-6048

Published Date: 5 October 2016

Original Research

Preventive effect of zoledronic acid on aromatase inhibitor-associated bone loss for postmenopausal breast cancer patients receiving adjuvant letrozole

Sun SL, Wang FC, Dou HL, Zhang LQ, Li JW

OncoTargets and Therapy 2016, 9:6029-6036

Published Date: 5 October 2016

Original Research

Recurrence pattern of squamous cell carcinoma in the midthoracic esophagus: implications for the clinical target volume design of postoperative radiotherapy

Wang X, Luo Y, Li M, Yan H, Sun M, Fan T

OncoTargets and Therapy 2016, 9:6021-6027

Published Date: 3 October 2016

Original Research

miR-590-5p regulates gastric cancer cell growth and chemosensitivity through RECK and the AKT/ERK pathway

Shen B, Yu S, Zhang Y, Yuan Y, Li X, Zhong J, Feng J

OncoTargets and Therapy 2016, 9:6009-6019

Published Date: 3 October 2016

Original Research

Infliximab enhances the therapeutic effects of 5-fluorouracil resulting in tumor regression in colon cancer

Liu F, Ai F, Tian L, Liu S, Zhao L, Wang X

OncoTargets and Therapy 2016, 9:5999-6008

Published Date: 3 October 2016

Original Research

CX-5461 induces autophagy and inhibits tumor growth via mammalian target of rapamycin-related signaling pathways in osteosarcoma

Li L, Li Y, Zhao J, Fan S, Wang L, Li X

OncoTargets and Therapy 2016, 9:5985-5997

Published Date: 29 September 2016

Original Research

Association analysis of DACT1 genetic variants and gastric cancer risk in a Chinese Han population: a case–control study

Huang C, Wang YN, Fan H, Ma X, Tang R, Huan XK, Zhu Y, Xu ZK, Xu H, Yang L

OncoTargets and Therapy 2016, 9:5975-5983

Published Date: 29 September 2016

Original Research

Expression of OVOL2 is related to epithelial characteristics and shows a favorable clinical outcome in hepatocellular carcinoma

Fu H, Qi L, Chen L, He Y, Zhang N, Guo H

OncoTargets and Therapy 2016, 9:5963-5973

Published Date: 29 September 2016

Original Research

Prognostic nutritional index predicts prognosis in patients with metastatic nasopharyngeal carcinoma

Wei GB, Lu YY, Liao RW, Chen QS, Zhang KQ

OncoTargets and Therapy 2016, 9:5955-5961

Published Date: 28 September 2016

Review

BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects

Abedin SM, Boddy CS, Munshi HG

OncoTargets and Therapy 2016, 9:5943-5953

Published Date: 28 September 2016

Original Research

MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches

Markowitz J, Abrams Z, Jacob NK, Zhang X, Hassani JN, Latchana N, Wei L, Regan KE, Brooks TR, Uppati SR, Levine KM, Bekaii-Saab T, Kendra KL, Lesinski GB, Howard JH, Olencki T, Payne PR, Carson WE III

OncoTargets and Therapy 2016, 9:5931-5941

Published Date: 29 September 2016

Original Research

The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study

Jia YX, Li TF, Zhang DD, Fan ZM, Fan HJ, Yan J, Chen LJ, Tang H, Qin YR, Li XY

OncoTargets and Therapy 2016, 9:5919-5929

Published Date: 27 September 2016

Original Research

Combination of cold atmospheric plasma and iron nanoparticles in breast cancer: gene expression and apoptosis study

Jalili A, Irani S, Mirfakhraie R

OncoTargets and Therapy 2016, 9:5911-5917

Published Date: 28 September 2016

Original Research

Complications of ultrasound-guided percutaneous microwave ablation of renal cell carcinoma

Dong XJ, Li X, Yu J, Yu MA, Yu XL, Liang P

OncoTargets and Therapy 2016, 9:5903-5909

Published Date: 26 September 2016

Original Research

Postoperative prophylactic hepatic arterial infusion chemotherapy for stage III colorectal cancer: a retrospective study

Wang Y, Sun XR, Feng WM, Bao Y, Zheng YY

OncoTargets and Therapy 2016, 9:5897-5902

Published Date: 26 September 2016

Original Research

Differential proteomics analysis of low- and high-grade of astrocytoma using iTRAQ quantification

Ren T, Lin SD, Wang ZF, Shang AJ

OncoTargets and Therapy 2016, 9:5883-5895

Published Date: 27 September 2016

Original Research

Radiation dose reduction for patients with extranodal NK/T-cell lymphoma with complete response after initial induction chemotherapy

Wang L, Bi XW, Xia ZJ, Huang HQ, Jiang WQ, Zhang YJ

OncoTargets and Therapy 2016, 9:5875-5881

Published Date: 26 September 2016

Original Research

The efficacy and safety of nivolumab in previously treated advanced non-small-cell lung cancer: a meta-analysis of prospective clinical trials

Huang J, Zhang Y, Sheng J, Zhang H, Fang W, Zhan J, Zhou T, Chen Y, Liu L, Zhang L

OncoTargets and Therapy 2016, 9:5867-5874

Published Date: 23 September 2016

Review

Spotlight on pembrolizumab in non-small cell lung cancer: the evidence to date

Vachhani P, Chen H

OncoTargets and Therapy 2016, 9:5855-5866

Published Date: 23 September 2016

Original Research

Nanoradiopharmaceuticals for breast cancer imaging: development, characterization, and imaging in inducted animals

Sarcinelli MA, Albernaz MS, Szwed M, Iscaife A, Leite KRM, Junqueira MS, Bernardes ES, da Silva EO, Tavares MIB, Santos-Oliveira R

OncoTargets and Therapy 2016, 9:5847-5854

Published Date: 23 September 2016

Clinical Trial Report

Safety and efficacy of sunitinib in patients from Latin America: subanalysis of an expanded access trial in metastatic renal cell carcinoma

Barrios CH, Herchenhorn D, Chacón M, Cabrera-Galeana P, Sajben P, Zhang K

OncoTargets and Therapy 2016, 9:5839-5845

Published Date: 23 September 2016

Review

Clinical use of cabozantinib in the treatment of advanced kidney cancer: efficacy, safety, and patient selection

Yu SS, Quinn DI, Dorff TB

OncoTargets and Therapy 2016, 9:5825-5837

Published Date: 23 September 2016

Original Research

An evaluation of the diagnostic efficacy of fine needle aspiration biopsy in patients operated for a thyroid nodular goiter

Janczak D, Pawlowski W, Dorobisz T, Janczak D, Dorobisz K, Leśniak M, Ziomek A, Chabowski M

OncoTargets and Therapy 2016, 9:5819-5823

Published Date: 22 September 2016

Original Research

Evaluation of c-Met, HGF, and HER-2 expressions in gastric carcinoma and their association with other clinicopathological factors

Yıldız Y, Sokmensuer C, Yalcin S

OncoTargets and Therapy 2016, 9:5809-5817

Published Date: 22 September 2016

Original Research

Anatomic distribution of supraclavicular lymph node in patients with esophageal cancer

Xing J, Luo Y, Wang X, Gao M, Sun M, Ding X, Fan T, Yu J

OncoTargets and Therapy 2016, 9:5803-5808

Published Date: 22 September 2016

Case report

A clear cell adenocarcinoma of the gallbladder with hepatoid differentiation: case report and review of literature

Zhang C, Zhang W, Mu D, Shi X, Zhao L

OncoTargets and Therapy 2016, 9:5797-5802

Published Date: 22 September 2016

Original Research

Apparent diffusion coefficient values detected by diffusion-weighted imaging in the prognosis of patients with locally advanced esophageal squamous cell carcinoma receiving chemoradiation

Liu S, Zhen F, Sun N, Chen J, Cao Y, Zhang S, Cheng H, Ge X, Sun X

OncoTargets and Therapy 2016, 9:5791-5796

Published Date: 21 September 2016

Case report

A case report and literature review of primary resistant Hodgkin lymphoma: a response to anti-PD-1 after failure of autologous stem cell transplantation and brentuximab vedotin

Xu PP, Wang F, Guan CY, Ouyang J, Shao XY, Chen B

OncoTargets and Therapy 2016, 9:5781-5789

Published Date: 21 September 2016

Original Research

Prognostic value of decreased microRNA-133a in solid cancers: a meta-analysis

Xiao J, Zou Y, Lu X, Xie B, Yu Q, He B, He B, Chen Q

OncoTargets and Therapy 2016, 9:5771-5779

Published Date: 21 September 2016

Original Research

Pretreatment neutrophil-to-lymphocyte ratio as a survival predictor for small-cell lung cancer

Wang X, Teng F, Kong L, Yu J

OncoTargets and Therapy 2016, 9:5761-5770

Published Date: 20 September 2016

Original Research

The expression of NEDD9 and E-cadherin correlates with metastasis and poor prognosis in triple-negative breast cancer patients

Li P, Sun T, Yuan Q, Pan G, Zhang J, Sun D

OncoTargets and Therapy 2016, 9:5751-5759

Published Date: 19 September 2016

Original Research

The role of semaphorin 4D in tumor development and angiogenesis in human breast cancer

Jiang HC, Chen CS, Sun QM, Wu J, Qiu LJ, Gao CE, Liu WQ, Yang J, Jun N, Dong J

OncoTargets and Therapy 2016, 9:5737-5750

Published Date: 26 September 2016

Original Research

Consolidation chemotherapy improves progression-free survival in stage III small-cell lung cancer following concurrent chemoradiotherapy: a retrospective study

Chen XR, Liang JZ, Ma SX, Fang WF, Zhou NN, Liao H, Li DL, Chen LK

OncoTargets and Therapy 2016, 9:5729-5736

Published Date: 19 September 2016

Review

Proton beam therapy: clinical utility and current status in prostate cancer

Yamoah K, Johnstone PA

OncoTargets and Therapy 2016, 9:5721-5727

Published Date: 16 September 2016

Original Research

A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer

Zhai N, Xia Y, Yin R, Liu J, Gao F

OncoTargets and Therapy 2016, 9:5713-5720

Published Date: 16 September 2016

Methodology

Identifying module biomarkers from gastric cancer by differential correlation network

Liu X, Chang X

OncoTargets and Therapy 2016, 9:5701-5711

Published Date: 19 September 2016

Retraction

Expression of PER, CRY, and TIM genes for the pathological features of colorectal cancer patients [Retraction]

Wang Y, Cheng Y, Yu G, Jia B, Hu Z, Zhang L

OncoTargets and Therapy 2016, 9:5699-5700

Published Date: 20 September 2016

Review

Clinical comparative investigation of efficacy and toxicity of cisplatin plus gemcitabine or plus Abraxane as first-line chemotherapy for stage III/IV non-small-cell lung cancer

Ai D, Guan Y, Liu XJ, Zhang CF, Wang P, Liang HL, Guo QS

OncoTargets and Therapy 2016, 9:5693-5698

Published Date: 16 September 2016

Original Research

MicroRNA expression profiles predict progression and clinical outcome in lung adenocarcinoma

Lin K, Xu T, He BS, Pan YQ, Sun HL, Peng HX, Hu XX, Wang SK

OncoTargets and Therapy 2016, 9:5679-5692

Published Date: 15 September 2016

Review

Sonidegib, a novel smoothened inhibitor for the treatment of advanced basal cell carcinoma

Doan HQ, Silapunt S, Migden MR

OncoTargets and Therapy 2016, 9:5671-5678

Published Date: 14 September 2016

Original Research

Weekly nanoparticle albumin bound-paclitaxel in combination with cisplatin versus weekly solvent-based paclitaxel plus cisplatin as first-line therapy in Chinese patients with advanced esophageal squamous cell carcinoma

Wang HY, Yao ZH, Tang H, Zhao Y, Zhang XS, Yao SN, Yang SJ, Liu YY

OncoTargets and Therapy 2016, 9:5663-5669

Published Date: 23 September 2016

Case report

Primary gastric anaplastic lymphoma kinase-negative anaplastic large-cell lymphoma

Tian C, Zhang Y

OncoTargets and Therapy 2016, 9:5659-5661

Published Date: 13 September 2016

Original Research

A retrospective study of neoadjuvant chemotherapy plus radical hysterectomy versus radical hysterectomy alone in patients with stage II cervical squamous cell carcinoma presenting as a bulky mass

Takatori E, Shoji T, Takada A, Nagasawa T, Omi H, Kagabu M, Honda T, Miura F, Takeuchi S, Sugiyama T

OncoTargets and Therapy 2016, 9:5651-5657

Published Date: 13 September 2016

Original Research

The association of PTEN hypermethylation and breast cancer: a meta-analysis

Luo S, Chen J, Mo X

OncoTargets and Therapy 2016, 9:5643-5650

Published Date: 12 September 2016

Review

Clinical utility of 5-aminolevulinic acid HCl to better visualize and more completely remove gliomas

Halani SH, Adamson DC

OncoTargets and Therapy 2016, 9:5629-5642

Published Date: 12 September 2016

Review

Eribulin in the management of inoperable soft-tissue sarcoma: patient selection and survival

Thomas C, Movva S

OncoTargets and Therapy 2016, 9:5619-5627

Published Date: 9 September 2016

Original Research

Prostate cancer patients may have an increased risk of coexisting advanced colorectal neoplasms

Ko SH, Baeg MK, Bae WJ, Kim P, Choi MG

OncoTargets and Therapy 2016, 9:5611-5617

Published Date: 9 September 2016

Original Research

Polymorphisms in the MTHFR gene are associated with recurrence risk in lymph node-positive breast cancer patients

Suner A, Buyukhatipoglu H, Aktas G, Kus T, Ulaslı M, Oztuzcu S, Kalender ME, Sevinc A, Kul S, Camci C

OncoTargets and Therapy 2016, 9:5603-5609

Published Date: 9 September 2016

Original Research

Correlation of PDK1 expression with clinicopathologic features and prognosis of hepatocellular carcinoma

Wang J, Liu F, Ao P, Li X, Zheng H, Wu D, Zhang N, She J, Yuan J, Wu X

OncoTargets and Therapy 2016, 9:5597-5602

Published Date: 9 September 2016

Original Research

Role of post mastectomy radiation therapy in breast cancer patients with T1–2 and 1–3 positive lymph nodes

Cihan YB, Sarigoz T

OncoTargets and Therapy 2016, 9:5587-5595

Published Date: 9 September 2016

Review

Proton therapy for early stage prostate cancer: is there a case?

Chan TY, Tan PW, Tang JI

OncoTargets and Therapy 2016, 9:5577-5586

Published Date: 9 September 2016

Review

The neutrophil lymphocyte ratio is associated with breast cancer prognosis: an updated systematic review and meta-analysis

Wei BJ, Yao MY, Xing CY, Wang W, Yao J, Hong Y, Liu Y, Fu PF

OncoTargets and Therapy 2016, 9:5567-5575

Published Date: 8 September 2016

Original Research

Accelerated partial breast irradiation in an Asian population: dosimetric findings and preliminary results of a multicatheter interstitial program

Koh YV, Tan PW, Buhari SA, Iau P, Chan CW, Shen L, Tan SH, Tang JI

OncoTargets and Therapy 2016, 9:5561-5566

Published Date: 8 September 2016

Original Research

Phosphoglycerate dehydrogenase is a novel predictor for poor prognosis in gastric cancer

Xian Y, Zhang S, Wang X, Qin J, Wang W, Wu H

OncoTargets and Therapy 2016, 9:5553-5560

Published Date: 7 September 2016

Original Research

The clinical effects of low-dose splenic irradiation combined with chest three-dimensional conformal radiotherapy on patients with locally advanced non-small-cell lung cancer: a randomized clinical trial

Yu H, Qu Y, Shang Q, Yan C, Jiang P, Wang X, Liang D, Jiang T

OncoTargets and Therapy 2016, 9:5545-5552

Published Date: 7 September 2016

Original Research

Novel chlorambucil-conjugated anionic linear-globular PEG-based second-generation dendrimer: in vitro/in vivo improved anticancer activity

Assadi A, Najafabadi VS, Shandiz SAS, Boroujeni AS, Ashrafi S, Vaziri AZ, Ghoreishi SM, Aghasadeghi MR, Ebrahimi SES, Pirali-Hamedani M, Ardestani MS

OncoTargets and Therapy 2016, 9:5531-5543

Published Date: 7 September 2016

Original Research

Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980–2013): an analysis of population-based data in relation to socio-economic changes

Banas T, Juszczyk G, Pitynski K, Nieweglowska D, Ludwin A, Czerw A

OncoTargets and Therapy 2016, 9:5521-5530

Published Date: 7 September 2016

Original Research

Polymorphisms in the XPC gene and gastric cancer susceptibility in a Southern Chinese population

Hua RX, Zhuo ZJ, Shen GP, Zhu J, Zhang SD, Xue WQ, Li XZ, Zhang PF, He J, Jia WH

OncoTargets and Therapy 2016, 9:5513-5519

Published Date: 7 September 2016

Case report

Lenalidomide, celecoxib, and azacitidine therapy for blastic plasmocytoid dendritic cell neoplasm: a case report

Garcia-Recio M, Martinez-Serra J, Bento L, Ramos R, Gines J, Daumal J, Sampol A, Gutierrez A

OncoTargets and Therapy 2016, 9:5507-5511

Published Date: 7 September 2016

Review

Sunitinib: the antiangiogenic effects and beyond

Hao Z, Sadek I

OncoTargets and Therapy 2016, 9:5495-5505

Published Date: 8 September 2016

Review

Osimertinib making a breakthrough in lung cancer targeted therapy

Zhang H

OncoTargets and Therapy 2016, 9:5489-5493

Published Date: 6 September 2016

Original Research

Clinical implications of the coexpression of SRC1 and NANOG in HER-2-overexpressing breast cancers

Jin CY, Zhang XY, Sun M, Zhang YF, Zhang GX, Wang B

OncoTargets and Therapy 2016, 9:5483-5488

Published Date: 6 September 2016

Original Research

A comparison study of pancreatic acinar cell carcinoma with ductal adenocarcinoma using computed tomography in Chinese patients

Wang Q, Wang X, Guo R, Li G

OncoTargets and Therapy 2016, 9:5475-5481

Published Date: 6 September 2016

Review

Next-generation EGFR/HER tyrosine kinase inhibitors for the treatment of patients with non-small-cell lung cancer harboring EGFR mutations: a review of the evidence

Wang X, Goldstein D, Crowe PJ, Yang JL

OncoTargets and Therapy 2016, 9:5461-5473

Published Date: 6 September 2016

Review

Association between insulin-like growth factor-binding protein-3 polymorphism -202 A/C and the risk of prostate cancer: a meta-analysis

Qin Z, Li X, Tang J, Jiang X, Yu Y, Wang C, Xu W, Hua Y, Yu B, Zhang W

OncoTargets and Therapy 2016, 9:5451-5459

Published Date: 6 September 2016

Original Research

Identifying candidate agents for lung adenocarcinoma by walking the human interactome

Sun Y, Zhang R, Jiang Z, Xia R, Zhang J, Liu J, Chen F

OncoTargets and Therapy 2016, 9:5439-5450

Published Date: 1 September 2016

Review

Clinical potential of necitumumab in non-small cell lung carcinoma

Genova C, Hirsch FR

OncoTargets and Therapy 2016, 9:5427-5437

Published Date: 31 August 2016

Original Research

Long noncoding RNA SPRY4-IT1 promotes malignant development of colorectal cancer by targeting epithelial–mesenchymal transition

Cao D, Ding Q, Yu W, Gao M, Wang Y

OncoTargets and Therapy 2016, 9:5417-5425

Published Date: 30 August 2016

Original Research

Efficacy and safety of anti-epidermal growth factor receptor therapy compared with anti-vascular endothelial growth factor therapy for metastatic colorectal cancer in first-line and second-line therapies: a meta-analysis

Wang H, Ma B, Gao P, Song Y, Xu Q, Hu Y, Zhang C, Wang Z

OncoTargets and Therapy 2016, 9:5405-5416

Published Date: 30 August 2016

Case report

Real-time tests of multiple genome alterations take the first steps into the clinic: a learning example

Gerratana L, De Maglio G, De Pellegrin A, Follador A, Rihawi K, Pizzolitto S, Puglisi F, Fasola G

OncoTargets and Therapy 2016, 9:5399-5404

Published Date: 30 August 2016

Original Research

Long-term results of definitive concurrent chemoradiotherapy using S-1 in the treatment of geriatric patients with esophageal cancer

Lv S, Fang M, Yang J, Zhan W, Jia Y, Xu H, Song T

OncoTargets and Therapy 2016, 9:5389-5397

Published Date: 6 September 2016

Original Research

Pitavastatin suppressed liver cancer cells in vitro and in vivo

You HY, Zhang WJ, Xie XM, Zheng ZH, Zhu HL, Jiang FZ

OncoTargets and Therapy 2016, 9:5383-5388

Published Date: 29 August 2016

Original Research

Verteporfin, a suppressor of YAP–TEAD complex, presents promising antitumor properties on ovarian cancer

Feng J, Gou J, Jia J, Yi T, Cui T, Li Z

OncoTargets and Therapy 2016, 9:5371-5381

Published Date: 29 August 2016

Original Research

Limb-salvage treatment of en-block resected distal femoral tumors with endoprosthesis of all-polyethylene tibial component: a 9-year follow-up study

Tang F, Zhou Y, Min L, Zhang WL, Shi R, Luo Y, Duan H, Tu CQ

OncoTargets and Therapy 2016, 9:5361-5369

Published Date: 13 September 2016

Original Research

ALDH1A1 induces resistance to CHOP in diffuse large B-cell lymphoma through activation of the JAK2/STAT3 pathway

Jiang J, Liu Y, Tang Y, Li L, Zeng R, Zeng S, Zhong M

OncoTargets and Therapy 2016, 9:5349-5360

Published Date: 29 August 2016

Original Research

The clinicopathological significance of RUNX3 hypermethylation and mRNA expression in human breast cancer, a meta-analysis

Song XY, Li BY, Zhou EX, Wu FX

OncoTargets and Therapy 2016, 9:5339-5347

Published Date: 26 August 2016

Original Research

Knockdown of peroxisome proliferator-activated receptor gamma coactivator-1 alpha increased apoptosis of human endometrial cancer HEC-1A cells

Yang H, Yang R, Liu H, Ren Z, Wang C, Li D, Ma X

OncoTargets and Therapy 2016, 9:5329-5338

Published Date: 24 August 2016

Original Research

Prognostic significance of pretreatment albumin/globulin ratio in patients with hepatocellular carcinoma

Deng Y, Pang Q, Miao RC, Chen W, Zhou YY, Bi JB, Liu SS, Zhang JY, Qu K, Liu C

OncoTargets and Therapy 2016, 9:5317-5328

Published Date: 24 August 2016

Original Research

Risk prediction and clinical model building for lymph node metastasis in papillary thyroid microcarcinoma

Lin DZ, Qu N, Shi RL, Lu ZW, Ji QH, Wu WL

OncoTargets and Therapy 2016, 9:5307-5316

Published Date: 24 August 2016

Original Research

Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells

Zhu L, Huang FZ, Deng G, Nie W, Huang W, Xu HB, Zheng SP, Yi ZJ, Wan T

OncoTargets and Therapy 2016, 9:5297-5305

Published Date: 24 August 2016

Clinical Trial Report

Noninvasive monitoring of the genetic evolution of EGFR-mutant non-small-cell lung cancer by analyzing circulating tumor DNA during combination chemotherapy with gefitinib and pemetrexed or S-1

Nakahara Y, Takagi Y, Hosomi Y, Kagei A, Yamamoto T, Sawada T, Yomota M, Okuma Y, Mikura S, Okamura T

OncoTargets and Therapy 2016, 9:5287-5295

Published Date: 24 August 2016

Original Research

An isolated orbital mass with proptosis and diplopia: an uncommon metastasis from intracranial olfactory neuroblastoma in a Chinese patient

Shen JQ, Cui HG, Feng S

OncoTargets and Therapy 2016, 9:5281-5286

Published Date: 24 August 2016

Original Research

Expression and prognostic significance of unique ULBPs in pancreatic cancer

Chen J, Zhu XX, Xu H, Fang HZ, Zhao JQ

OncoTargets and Therapy 2016, 9:5271-5279

Published Date: 25 August 2016

Original Research

Correlations between EGFR gene polymorphisms and pleural metastasis of lung adenocarcinoma

Guo HS, Xing YH, Mu AL, Li X, Li TS, Bian X, Yang CM, Zhang XL, Liu YF, Wang XG

OncoTargets and Therapy 2016, 9:5257-5270

Published Date: 25 August 2016

Original Research

MicroRNA-210 interacts with FBXO31 to regulate cancer proliferation cell cycle and migration in human breast cancer

Liu D, Xia H, Wang F, Chen C, Long J

OncoTargets and Therapy 2016, 9:5245-5255

Published Date: 23 August 2016

Review

Prognostic significance of TAZ expression in various cancers: a meta-analysis

Feng J, Ren P, Gou J, Li Z

OncoTargets and Therapy 2016, 9:5235-5244

Published Date: 23 August 2016

Original Research

Association between BHMT gene rs3733890 polymorphism and cancer risk: evidence from a meta-analysis

Xu Y, Yan C, Hao Z, Zhou J, Fan S, Tai S, Yang C, Zhang L, Liang C

OncoTargets and Therapy 2016, 9:5225-5233

Published Date: 22 August 2016

Original Research

Evaluation of the characteristics of hepatic focal nodular hyperplasia: correlation between dynamic contrast-enhanced multislice computed tomography and pathological findings

Zhang HT, Gao XY, Xu QS, Chen YT, Song YP, Yao ZW

OncoTargets and Therapy 2016, 9:5217-5224

Published Date: 22 August 2016

Original Research

Surgical procedures for papillary thyroid carcinoma located in the thyroid isthmus: an intention-to-treat analysis

Lei JY, Zhu JQ, Li ZH, Gong RX, Wei T

OncoTargets and Therapy 2016, 9:5209-5216

Published Date: 22 August 2016

Review

B-cell-specific Moloney murine leukemia virus integration site 1: potential stratification factor and therapeutic target for epithelial ovarian cancer

Zhao Q, Gui T, Qian Q, Li L, Shen K

OncoTargets and Therapy 2016, 9:5203-5208

Published Date: 22 August 2016

Original Research

Effect of DcR3-specific siRNA on cell growth suppression and apoptosis induction in glioma cells via affecting ERK and AKT

Zhang Y, Huang SN, Leng YH, Chen X, Liu TT, Wang HL, Wei FL, Luo DZ, Chen G, Wei ZX

OncoTargets and Therapy 2016, 9:5195-5202

Published Date: 29 August 2016

Original Research

MiR-126 regulates proliferation and invasion in the bladder cancer BLS cell line by targeting the PIK3R2-mediated PI3K/Akt signaling pathway

Xiao J, Lin HY, Zhu YY, Zhu YP, Chen LW

OncoTargets and Therapy 2016, 9:5181-5193

Published Date: 22 August 2016

Original Research

Lower expressed miR-198 and its potential targets in hepatocellular carcinoma: a clinicopathological and in silico study

Huang WT, Wang HL, Yang H, Ren FH, Luo YH, Huang CQ, Liang YY, Liang HW, Chen G, Dang YW

OncoTargets and Therapy 2016, 9:5163-5180

Published Date: 22 August 2016

Original Research

EGFR protein expression using a specific intracellular domain antibody and PTEN and clinical outcomes in squamous cell lung cancer patients with EGFR-tyrosine kinase inhibitor therapy

Chang H, Oh J, Zhang X, Kim YJ, Lee JH, Lee CT, Chung JH, Lee JS

OncoTargets and Therapy 2016, 9:5153-5162

Published Date: 19 August 2016

Original Research

Meta-analysis of the prognostic value of abnormally expressed lncRNAs in hepatocellular carcinoma

Qu Z, Yuan CH, Yin CQ, Guan Q, Chen H, Wang FB

OncoTargets and Therapy 2016, 9:5143-5152

Published Date: 18 August 2016

Original Research

Co-expression of periostin and EGFR in patients with esophageal squamous cell carcinoma and their prognostic significance

Jia W, Wang W, Ji CS, Niu JY, Lv YJ, Zhou HC, Hu B

OncoTargets and Therapy 2016, 9:5133-5142

Published Date: 18 August 2016

Original Research

Comparison of the short-term efficacy between docetaxel plus carboplatin and 5-fluorouracil plus carboplatin in locoregionally advanced nasopharyngeal carcinoma

Lv X, Xia WX, Ke LR, Yang J, Qiu WZ, Yu YH, Liang H, Huang XJ, Liu GY, Zeng Q, Guo X, Xiang YQ

OncoTargets and Therapy 2016, 9:5123-5131

Published Date: 18 August 2016

Original Research

Comparison of long-term survival between temozolomide-based chemoradiotherapy and radiotherapy alone for patients with low-grade gliomas after surgical resection

Gai XJ, Wei YM, Tao HM, An DZ, Sun JT, Li BS

OncoTargets and Therapy 2016, 9:5117-5121

Published Date: 17 August 2016

Review

Immune checkpoint inhibitors: the new frontier in non–small cell lung cancer treatment

El-Osta HE, Shahid K, Mills GM, Peddi P

OncoTargets and Therapy 2016, 9:5101-5116

Published Date: 16 August 2016

Original Research

MiR-200c promotes bladder cancer cell migration and invasion by directly targeting RECK

Cheng Y, Zhang X, Li P, Yang C, Tang J, Deng X, Yang X, Tao J, Lu Q, Li P

OncoTargets and Therapy 2016, 9:5091-5099

Published Date: 16 August 2016

Original Research

The clinicopathological significance of hMLH1 hypermethylation in non-small-cell lung cancer: a meta-analysis and literature review

Han Y, Shi K, Zhou SJ, Yu DP, Liu ZD

OncoTargets and Therapy 2016, 9:5081-5090

Published Date: 16 August 2016

Original Research

Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breast cancer patients treated with paclitaxel and docetaxel

Kus T, Aktas G, Kalender ME, Demiryurek AT, Ulasli M, Oztuzcu S, Sevinc A, Kul S, Camci C

OncoTargets and Therapy 2016, 9:5073-5080

Published Date: 12 August 2016

Original Research

Clinicopathological role of miR-30a-5p in hepatocellular carcinoma tissues and prediction of its function with bioinformatics analysis

Huang WT, Chen ZX, He RQ, Wu YZ, Yin SY, Liang XN, Chen G, Yang H, Peng ZG, Yang LH

OncoTargets and Therapy 2016, 9:5061-5071

Published Date: 12 August 2016

Original Research

Tf-PEG-PLL-PLGA nanoparticles enhanced chemosensitivity for hypoxia-responsive tumor cells

Liu P, Zhang H, Wu X, Guo L, Wang F, Xia G, Chen B, Yin H, Wang Y, Li X

OncoTargets and Therapy 2016, 9:5049-5059

Published Date: 12 August 2016

Original Research

New utility of an old marker: serum low-density lipoprotein predicts histopathological response of neoadjuvant chemotherapy in locally advanced gastric cancer

Zhou JC, Guo JF, Teng RY, Wang QC, Wang J, Wei Q, Li ZD, Shen JG, Wang LB

OncoTargets and Therapy 2016, 9:5041-5047

Published Date: 12 August 2016

Review

PD-L1 expression in human cancers and its association with clinical outcomes

Wang X, Teng FF, Kong L, Yu JM

OncoTargets and Therapy 2016, 9:5023-5039

Published Date: 12 August 2016

Original Research

Tumor size interpretation for predicting cervical lymph node metastasis using a differentiated thyroid cancer risk model

Shi RL, Qu N, Yang SW, Ma B, Lu ZW, Wen D, Sun GH, Wang Y, Ji QH

OncoTargets and Therapy 2016, 9:5015-5022

Published Date: 12 August 2016

Original Research

Long noncoding RNA ZNFX1-AS1 suppresses growth of hepatocellular carcinoma cells by regulating the methylation of miR-9

Wang T, Ma SC, Qi X, Tang X, Cui D, Wang Z, Chi J, Li P, Zhai B

OncoTargets and Therapy 2016, 9:5005-5014

Published Date: 12 August 2016

Original Research