Grossmann NC, Schuettfort VM, Pradere B, Moschini M, Quhal F, Mostafaei H, Soria F, Katayama S, Laukhtina E, Mori K, Sari Motlagh R, Poyet C, Abufaraj M, Karakiewicz PI, Shariat SF, D’Andrea D

OncoTargets and Therapy 2021, 14:315-324

Published Date: 13 January 2021

Original Research

Physalis alkekengi var. franchetii Extracts Exert Antitumor Effects on Non-Small Cell Lung Cancer and Multiple Myeloma by Inhibiting STAT3 Signaling

Fu Y, Zhu F, Ma Z, Lv B, Wang X, Dai C, Ma X, Liu P, Lv H, Chen X, Chen Z, Shen L

OncoTargets and Therapy 2021, 14:301-314

Published Date: 12 January 2021

Original Research

Lobaplatin Enhances Radioactive 125I Seed-Induced Apoptosis and Anti-Proliferative Effect in Non-Small Cell Lung Cancer by Suppressing the AKT/mTOR Pathway

Rong J, Li D, Li Y

OncoTargets and Therapy 2021, 14:289-300

Published Date: 12 January 2021

Review

The Biological Roles of Exosomal Long Non-Coding RNAs in Cancers

Da M, Jiang H, Xie Y, Jin W, Han S

OncoTargets and Therapy 2021, 14:271-287

Published Date: 12 January 2021

Original Research

GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial–Mesenchymal Transition

Gong L, Cai L, Li G, Cai J, Yi X

OncoTargets and Therapy 2021, 14:255-269

Published Date: 12 January 2021

Corrigendum

LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling [Corrigendum]

Wang Q, Liao J, He Z, Su Y, Lin D, Xu L, Xu H, Lin J

OncoTargets and Therapy 2021, 14:253-254

Published Date: 12 January 2021

Original Research

Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy

Lu Y, Li L, Chen H, Jing X, Wang M, Ge L, Yang J, Zhang M, Tang X

OncoTargets and Therapy 2021, 14:239-251

Published Date: 12 January 2021

Original Research

Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells

Wu J, Sun L, Liu T, Dong G

OncoTargets and Therapy 2021, 14:221-237

Published Date: 11 January 2021

Original Research

The Plasma Concentration of D-Dimer is Associated with Neoadjuvant-Chemotherapy Efficacy and the Prognosis in Osteosarcoma

Huang Y, Shen Z, Yao Y, He A, Min D

OncoTargets and Therapy 2021, 14:213-220

Published Date: 11 January 2021

Original Research

ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes

Li R, Li Y, Qin H, Li S

OncoTargets and Therapy 2021, 14:199-211

Published Date: 13 January 2021

Original Research

A Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells

Lv X, Zhang J, Zhang J, Guan W, Ren W, Liu Y, Xu G

OncoTargets and Therapy 2021, 14:187-198

Published Date: 8 January 2021

Case report

Multi Cytogenetic Changes in a Patient as Co-Existing MDS and CLL Progresses

Li X, Ma J, Wang L, Yan S, Li F, Wang L, Wang L, Li G, Ma D, Li H

OncoTargets and Therapy 2021, 14:177-186

Published Date: 8 January 2021

Original Research

Upregulation of miR-137 Expression Suppresses Tumor Growth and Progression via Interacting with DNMT3a Through Inhibiting the PTEN/Akt Signaling in HCC

Wang J, Wang Z, Yuan J, Wang Q, Shen X

OncoTargets and Therapy 2021, 14:165-176

Published Date: 8 January 2021

Original Research

LncRNA DDX11-AS1 Exerts Oncogenic Roles in Glioma Through Regulating miR-499b-5p/RWDD4 Axis

Zheng Y, Xie J, Xu X, Yang X, Zhou Y, Yao Q, Xiong Y

OncoTargets and Therapy 2021, 14:157-164

Published Date: 8 January 2021

Original Research

ALYREF Drives Cancer Cell Proliferation Through an ALYREF-MYC Positive Feedback Loop in Glioblastoma

Wang J, Li Y, Xu B, Dong J, Zhao H, Zhao D, Wu Y

OncoTargets and Therapy 2021, 14:145-155

Published Date: 8 January 2021

Case report

Rare Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review

Wang N, Dong SS, Wu CL, Wang Y, Meng L, Ren Y, Cui XB, Li M, Qi Y

OncoTargets and Therapy 2021, 14:139-144

Published Date: 8 January 2021

Original Research

PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma

Li H, Liu Q, Xiao K, He Z, Wu C, Sun J, Chen X, Chen S, Yang J, Ma Q, Su J

OncoTargets and Therapy 2021, 14:125-138

Published Date: 8 January 2021

Retraction

Exosomal miR-638 Inhibits Hepatocellular Carcinoma Progression by Targeting SP1 [Retraction]

Yang J, Li B, Zhao S, Du H, Du Y

OncoTargets and Therapy 2021, 14:123-124

Published Date: 8 January 2021

Original Research

Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene

Luo Y, Yu P, Zhao J, Guo Q, Fan B, Diao Y, Jin Y, Wu J, Zhang C

OncoTargets and Therapy 2021, 14:111-122

Published Date: 7 January 2021

Original Research

Circ_0007444 Inhibits the Progression of Ovarian Cancer via Mediating the miR-570-3p/PTEN Axis

Wu X, Liu D, Wang S, Liu J

OncoTargets and Therapy 2021, 14:97-110

Published Date: 7 January 2021

Original Research

Circ_0006404 Accelerates Prostate Cancer Progression Through Regulating miR-1299/CFL2 Signaling

Li P, Wang Z, Li S, Wang L

OncoTargets and Therapy 2021, 14:83-95

Published Date: 6 January 2021

Original Research

Silencing of MicroRNA-503 in Rat Mesenchymal Stem Cells Exerts Potent Antitumorigenic Effects in Lung Cancer Cells

Huang B, Feng Z, Zhu L, Zhang S, Duan J, Zhao C, Zhang X

OncoTargets and Therapy 2021, 14:67-81

Published Date: 6 January 2021

Review

Aberrant Factors of Fibrinolysis and Coagulation in Pancreatic Cancer

Fang L, Xu Q, Qian J, Zhou JY

OncoTargets and Therapy 2021, 14:53-65

Published Date: 6 January 2021

Original Research

Clinicopathological and Prognostic Significance of Immunoscore and PD-L1 in Intrahepatic Cholangiocarcinoma

Wu H, Wei Y, Jian M, Lu H, Song Q, Hao L, Yue Y

OncoTargets and Therapy 2021, 14:39-51

Published Date: 6 January 2021

Original Research

Prognostic Value of Pretreatment Serum Cystatin C Level in Nasopharyngeal Carcinoma Patients in the Intensity-modulated Radiotherapy Era

Tan XR, Huang SY, Gong S, Chen Y, Yang XJ, He QM, He SW, Liu N, Li YQ

OncoTargets and Therapy 2021, 14:29-37

Published Date: 6 January 2021

Original Research

MiRNA-1225 Inhibits Osteosarcoma Tumor Growth and Progression by Targeting YWHAZ

Gong Y, Wei Z, Liu J

OncoTargets and Therapy 2021, 14:15-27

Published Date: 6 January 2021

Original Research

Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression

He J, Guan J, Liao S, Wu Z, Liu B, Mo H, Yuan Z

OncoTargets and Therapy 2021, 14:1-13

Published Date: 6 January 2021

Review

Mechanisms and Functions of MiR-200 Family in Hepatocellular Carcinoma

Mao Y, Chen W, Wu H, Liu C, Zhang J, Chen S

OncoTargets and Therapy 2020, 13:13479-13490

Published Date: 5 January 2021

Original Research

Biostable Double-Strand Circular Aptamers Conjugated Onto Dendrimers for Specific Capture and Inhibition of Circulating Leukemia Cells

Li Y, Zhang T, Huang J, Dong H, Xie J, Jia L

OncoTargets and Therapy 2020, 13:13465-13477

Published Date: 5 January 2021

Original Research

Overexpression of a Long Non-Coding RNA BC037916 is Associated with Pancreatic Tumorigenesis and Poor Prognosis

Chen G, Xu L, Ye G, Lin J, Meng Z, Shen Y

OncoTargets and Therapy 2020, 13:13451-13463

Published Date: 5 January 2021

Original Research

ERK Activation-Mediated Autophagy Induction Resists Licochalcone A-Induced Anticancer Activities in Lung Cancer Cells in vitro

Luo W, Sun R, Chen X, Li J, Jiang J, He Y, Shi S, Wen H

OncoTargets and Therapy 2020, 13:13437-13450

Published Date: 8 January 2021

Original Research

The Impact of Acquired EGFR T790M Mutation and EGFR Circulating Cell-Free DNA on Survival in Patients with Lung Adenocarcinoma Following EGFR-TKI Therapy

Cheng WC, Hsia TC, Tu CY, Chen HJ

OncoTargets and Therapy 2020, 13:13425-13435

Published Date: 5 January 2021

Original Research

LncRNA LINC00511 Acts as an Oncogene in Colorectal Cancer via Sponging miR-29c-3p to Upregulate NFIA

Hu Y, Zhang Y, Ding M, Xu R

OncoTargets and Therapy 2020, 13:13413-13424

Published Date: 5 January 2021

Original Research

TRIM47 Promotes the Development of Glioma by Ubiquitination and Degradation of FOXO1

Wei H, Ding C, Zhuang H, Hu W

OncoTargets and Therapy 2020, 13:13401-13411

Published Date: 31 December 2020

Original Research

LncRNA GIHCG Promotes the Development of Esophageal Cancer by Modulating miR-29b-3p/ANO1 Axis

Zhao W, Huang Z, Liu H, Wang C

OncoTargets and Therapy 2020, 13:13387-13400

Published Date: 31 December 2020

Original Research

Circular RNA circGSE1 Promotes Cervical Cancer Progression Through miR-138-5p/Vimentin

Fan S, Zhao S, Gao X, Qin Q, Guo Y, Yuan Z, Zhang M, Liu Q, Li H

OncoTargets and Therapy 2020, 13:13371-13386

Published Date: 31 December 2020

Original Research

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells

Alhoshani A, Alatawi FO, Al-Anazi FE, Attafi IM, Zeidan A, Agouni A, El Gamal HM, Shamoon LS, Khalaf S, Korashy HM

OncoTargets and Therapy 2020, 13:13357-13370

Published Date: 31 December 2020

Review

Individualized Management of Blood Concentration in Patients with Gastrointestinal Stromal Tumors

Xu H, Liu Q

OncoTargets and Therapy 2020, 13:13345-13355

Published Date: 5 January 2021

Review

The Roles of Integrin α5β1 in Human Cancer

Hou J, Yan D, Liu Y, Huang P, Cui H

OncoTargets and Therapy 2020, 13:13329-13344

Published Date: 31 December 2020

Original Research

Circ_0001175 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis by Regulating miR-130a-5p

Li L, He K, Chen S, Wei W, Tian Z, Tang Y, Xiao C, Xiang G

OncoTargets and Therapy 2020, 13:13315-13327

Published Date: 31 December 2020

Case report

Effective Treatment of NSCLC with Surgery After Nivolumab Combined with Chemotherapy: A Case Report and Brief Review of the Literature

Zhao L, Li L, Chen T, Fang C

OncoTargets and Therapy 2020, 13:13307-13313

Published Date: 30 December 2020

Clinical Trial Report

Impact of Programmed Death Ligand 1 Expression in Advanced Non-Small–Cell Lung Cancer Patients, Treated by Chemotherapy (GFPC 06-2015 Study)

Auliac JB, Guisier F, Bizieux A, Assouline P, Bernardini M, Lamy R, Justeau G, François G, Damotte D, Chouaïd C

OncoTargets and Therapy 2020, 13:13299-13305

Published Date: 30 December 2020

Original Research

Expression and Prognostic Role of PLOD1 in Malignant Glioma

Wang H, Luo W, Dai L

OncoTargets and Therapy 2020, 13:13285-13297

Published Date: 29 December 2020

Original Research

Bioinformatics Analysis of Key Genes and Pathways of Cervical Cancer

Chen H, Wang X, Jia H, Tao Y, Zhou H, Wang M, Wang X, Fang X

OncoTargets and Therapy 2020, 13:13275-13283

Published Date: 29 December 2020

Original Research

Prognostic Value of Preoperative Albumin-to-Alkaline Phosphatase Ratio in Patients with Muscle-Invasive Bladder Cancer After Radical Cystectomy

Zhao M, Zhang M, Wang Y, Yang X, Teng X, Chu G, Wang X, Niu H

OncoTargets and Therapy 2020, 13:13265-13274

Published Date: 29 December 2020

Review

A Clinical Evaluation of Enzalutamide in Metastatic Castration-Sensitive Prostate Cancer: Guiding Principles for Treatment Selection and Perspectives on Research

Laccetti AL, Morris MJ, Kantoff PW

OncoTargets and Therapy 2020, 13:13247-13263

Published Date: 29 December 2020

Original Research

High Centromere Protein-A (CENP-A) Expression Correlates with Progression and Prognosis in Gastric Cancer

Xu Y, Liang C, Cai X, Zhang M, Yu W, Shao Q

OncoTargets and Therapy 2020, 13:13237-13246

Published Date: 29 December 2020

Review

RNA-Binding Motif Protein 38 as a Potential Biomarker and Therapeutic Target in Cancer

She X, Lin Y, Liang R, Liu Z, Gao X, Ye J

OncoTargets and Therapy 2020, 13:13225-13236

Published Date: 24 December 2020

Original Research

Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway

Guo M, Li S, Zhao X, Yuan Y, Zhang B, Guan Y

OncoTargets and Therapy 2020, 13:13211-13224

Published Date: 24 December 2020

Original Research

Comparative Study of Lipophilic Statin Activity in 2D and 3D in vitro Models of Human Breast Cancer Cell Lines MDA-MB-231 and MCF-7

Bytautaite M, Petrikaite V

OncoTargets and Therapy 2020, 13:13201-13209

Published Date: 24 December 2020

Review

Targeting BRD9 for Cancer Treatment: A New Strategy

Zhu X, Liao Y, Tang L

OncoTargets and Therapy 2020, 13:13191-13200

Published Date: 24 December 2020

Original Research

The effect of allicin on cell proliferation and apoptosis compared to blank control and cis-platinum in oral tongue squamous cell carcinoma

Guo Y, Liu H, Chen Y, Yan W

OncoTargets and Therapy 2020, 13:13183-13189

Published Date: 29 December 2020

Original Research

The lncRNA LINC00691 Functions as a ceRNA for miRNA-1256 to Suppress Osteosarcoma by Regulating the Expression of ST5

Wan D, Qu Y, Zhang L, Ai S, Cheng L

OncoTargets and Therapy 2020, 13:13171-13181

Published Date: 24 December 2020

Original Research

Interactions Between lncRNA TUG1 and miR-9-5p Modulate the Resistance of Breast Cancer Cells to Doxorubicin by Regulating eIF5A2

Wang S, Cheng M, Zheng X, Zheng L, Liu H, Lu J, Liu Y, Chen W

OncoTargets and Therapy 2020, 13:13159-13170

Published Date: 23 December 2020

Review

The Current State of Research Regarding the Role of Non-Coding RNAs in Cutaneous Squamous Cell Carcinoma

Chen S, Luo L, Chen H, He C

OncoTargets and Therapy 2020, 13:13151-13158

Published Date: 23 December 2020

Case report

Cutaneous Metastasis as the First Presentation of Non-Small-Cell Lung Cancer with a BRAF Mutation: A Case Report

Wang X, Wang H, Jia B, He F, Yuan Y, Zhang W

OncoTargets and Therapy 2020, 13:13143-13149

Published Date: 23 December 2020

Original Research

Fentanyl Inhibits Lung Cancer Viability and Invasion via Upregulation of miR-331-3p and Repression of HDAC5

Gong S, Ying L, Fan Y, Sun Z

OncoTargets and Therapy 2020, 13:13131-13141

Published Date: 23 December 2020

Original Research

Pretreatment Albumin-to-Fibrinogen Ratio Independently Predicts Chemotherapy Response and Prognosis in Patients with Locally Advanced Rectal Cancer Undergoing Total Mesorectal Excision After Neoadjuvant Chemoradiotherapy

Li H, Wang H, Shao S, Gu Y, Yao J, Huang J

OncoTargets and Therapy 2020, 13:13121-13130

Published Date: 23 December 2020

Original Research

Serum Calcium Levels Before Antitumour Therapy Predict Clinical Outcomes in Patients with Nasopharyngeal Carcinoma

Huang SY, Chen Y, Tan XR, Gong S, Yang XJ, He QM, He SW, Liu N, Li YQ

OncoTargets and Therapy 2020, 13:13111-13119

Published Date: 23 December 2020

Original Research

LncRNA MIR205HG Drives Esophageal Squamous Cell Carcinoma Progression by Regulating miR-214/SOX4 Axis

Li H, Jia J, Yang L, Chu J, Sheng J, Wang C, Meng W, Jia Z, Yin H, Wan J, He F

OncoTargets and Therapy 2020, 13:13097-13109

Published Date: 22 December 2020

Original Research

Brain Metastases of Non-Small Cell Lung Cancer: Magnetic Resonance Spectroscopy for Clinical Outcome Assessment in Patients with Stereotactic Radiotherapy

Jia C, Li Z, Guo D, Zhang Z, Yu J, Jiang G, Xing X, Ji S, Jin F

OncoTargets and Therapy 2020, 13:13087-13096

Published Date: 22 December 2020

Original Research

Preliminary Study on the Identification of BRAFV600E Mutation in Colorectal Cancer by Near-Infrared Spectroscopy

Duan J, Yang Y, Yin L, Zhang X, Tang Y, Zhang S, Gong H, Xiao M, Li M, Li Q, Li X, Yang L, Fan Q, Wang Y

OncoTargets and Therapy 2020, 13:13077-13085

Published Date: 22 December 2020

Original Research

Novel Small Molecular Compound AE-848 Potently Induces Human Multiple Myeloma Cell Apoptosis by Modulating the NF-κB and PI3K/Akt/mTOR Signaling Pathways

Xu Y, Feng X, Zhou Q, Jiang W, Dai Y, Jiang Y, Liu X, Li S, Wang Y, Wang F, Li A, Zheng C

OncoTargets and Therapy 2020, 13:13063-13075

Published Date: 22 December 2020

Original Research

Immunohistochemical Analysis of PGC-1α and ERRα Expression Reveals Their Clinical Significance in Human Ovarian Cancer

Huang X, Ruan G, Liu G, Gao Y, Sun P

OncoTargets and Therapy 2020, 13:13055-13062

Published Date: 22 December 2020

Original Research

Identifying an Eight-Gene Signature to Optimize Overall Survival Prediction of Esophageal Adenocarcinoma Using Bioinformatics Analysis of ceRNA Network

Wang Y, Liang N, Xue Z, Xue X

OncoTargets and Therapy 2020, 13:13041-13054

Published Date: 22 December 2020

Original Research

Overexpression of LncRNA SNHG1 Were Suitable for Oncolytic Adenoviruse H101 Therapy in Oral Squamous-Cell Carcinoma

Wang X, Yang S, Lv X, Wang L, Li C

OncoTargets and Therapy 2020, 13:13033-13039

Published Date: 21 December 2020

Review

Progress in Understanding the IL-6/STAT3 Pathway in Colorectal Cancer

Lin Y, He Z, Ye J, Liu Z, She X, Gao X, Liang R

OncoTargets and Therapy 2020, 13:13023-13032

Published Date: 21 December 2020

Case report

Primary Diffuse Large B-Cell Lymphoma of the Female Urethra: A Case Report and Review of the Literature

Zeng H, Wang J, Deng R, Chen Z

OncoTargets and Therapy 2020, 13:13015-13022

Published Date: 21 December 2020

Original Research

Long Noncoding RNA LINC00963 Promotes CDC5L-Mediated Malignant Progression in Gastric Cancer

Zhu H, Tang JH, Zhang SM, Qian JP, Ling X, Wu XY, Yang LX

OncoTargets and Therapy 2020, 13:12999-13013

Published Date: 22 December 2020

Original Research

MiR-519d and miR-328-3p Combinatorially Suppress Breast Cancer Progression

Ma H, Liu T, Xu Y, Wang X, Wang J, Liu X

OncoTargets and Therapy 2020, 13:12987-12997

Published Date: 18 December 2020

Case report

Niraparib as Maintenance Therapy in Germline ATM-mutated and Somatic BRCA2-mutated Ovarian Cancer with Brain Metastases: A Case Report and Literature Review

Tao M, Cheng J, Wu X

OncoTargets and Therapy 2020, 13:12979-12986

Published Date: 18 December 2020

Original Research

Profiling and Integrated Analysis of Differentially Expressed Circular RNAs in Plasma Exosomes as Novel Biomarkers for Advanced-Stage Lung Adenocarcinoma

Lin S, Xiong W, Liu H, Pei L, Yi H, Guan Y

OncoTargets and Therapy 2020, 13:12965-12977

Published Date: 18 December 2020

Original Research

Knockdown of Long Non-Coding RNA LOC100132707 Inhibits the Migration of Uveal Melanoma Cells via Silencing JAK2

Qi Y, Yao R, Zhang W, Cui Q, Zhang F

OncoTargets and Therapy 2020, 13:12955-12964

Published Date: 17 December 2020

Original Research

LncRNA SNHG16 Regulates the Progress of Acute Myeloid Leukemia Through miR183-5p–FOXO1 Axis

Yang R, Ma D, Wu Y, Zhang Y, Zhang L

OncoTargets and Therapy 2020, 13:12943-12954

Published Date: 17 December 2020

Original Research

Clinicopathological Characteristics of TZAP Expression in Colorectal Cancers

Jung SJ, Seo YR, Park WJ, Heo YR, Lee YH, Kim S, Lee JH

OncoTargets and Therapy 2020, 13:12933-12942

Published Date: 17 December 2020

Original Research

Gastric H+/K+-ATPase Expression in Normal Laryngeal Tissue and Laryngeal Carcinoma

Bao YY, Jiang Q, Li ZW, Yu E, Zhou SH, Yao HT, Fan J, Yong WW

OncoTargets and Therapy 2020, 13:12919-12931

Published Date: 17 December 2020

Original Research

Effect of Ect2 Expression on the Growth of Triple-Negative Breast Cancer Cells with Paclitaxel Intervention

Wang H, Liu H, Li J, Wei S, Liu X, Wan H, Zheng P, Zheng H

OncoTargets and Therapy 2020, 13:12905-12918

Published Date: 16 December 2020

Original Research

AHNAK2 Promotes Migration, Invasion, and Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Cells via the TGF-β/Smad3 Pathway

Liu G, Guo Z, Zhang Q, Liu Z, Zhu D

OncoTargets and Therapy 2020, 13:12893-12903

Published Date: 16 December 2020

Original Research

Apolipoprotein C1 (APOC1): A Novel Diagnostic and Prognostic Biomarker for Cervical Cancer

Shi X, Wang J, Dai S, Qin L, Zhou J, Chen Y

OncoTargets and Therapy 2020, 13:12881-12891

Published Date: 15 December 2020

Original Research

Role of Lipids and Apolipoproteins in Predicting the Prognosis of Hepatocellular Carcinoma After Resection

Ni XC, Yi Y, Fu YP, Cai XY, Liu G, Huang JL, Gan W, Xu J, Qiu SJ

OncoTargets and Therapy 2020, 13:12867-12880

Published Date: 16 December 2020

Original Research

Lower Serum Matrix Metalloproteinase‑9 in Metastatic Patients with Esophageal Squamous Cell Carcinoma After Concurrent Radiotherapy Was Significant for Prognosis

Ye Z, Zhao H, Zhou W, Ye T, Geng C, Li X, Yuan L, Du M, Xu H, Wang Q

OncoTargets and Therapy 2020, 13:12857-12866

Published Date: 15 December 2020

Review

The Potential Role of N6-Methyladenosine (m6A) Demethylase Fat Mass and Obesity-Associated Gene (FTO) in Human Cancers

Wang J, Chen L, Qiang P

OncoTargets and Therapy 2020, 13:12845-12856

Published Date: 15 December 2020

Original Research

Tumor-Linked Macrophages Promote HCC Development by Mediating the CCAT1/Let-7b/HMGA2 Signaling Pathway

Deng L, Huang S, Chen B, Tang Y, Huang F, Li D, Tang D

OncoTargets and Therapy 2020, 13:12829-12843

Published Date: 14 December 2020

Original Research

Endostar Rebuilding Vascular Homeostasis and Enhancing Chemotherapy Efficacy in Cervical Cancer Treatment

Guan L

OncoTargets and Therapy 2020, 13:12811-12827

Published Date: 14 December 2020

Original Research

Mutational Characterization and Potential Prognostic Biomarkers of Chinese Patients with Esophageal Squamous Cell Carcinoma

Zhang N, Shi J, Shi X, Chen W, Liu J

OncoTargets and Therapy 2020, 13:12797-12809

Published Date: 14 December 2020

Original Research

Downregulation of IRAK1 Prevents the Malignant Behavior of Hepatocellular Carcinoma Cells by Blocking Activation of the MAPKs/NLRP3/IL-1β Pathway

Chen W, Wei T, Chen Y, Yang L, Wu X

OncoTargets and Therapy 2020, 13:12787-12796

Published Date: 14 December 2020

Original Research

PD-1/PD-L1 Inhibitor Combined with Chemotherapy Can Improve the Survival of Non-Small Cell Lung Cancer Patients with Brain Metastases

Sun C, Zhou F, Li X, Zhao C, Li W, Li J, Xiong A, Yu J, Gao G, Wang Q, Wu F, Zhou C

OncoTargets and Therapy 2020, 13:12777-12786

Published Date: 14 December 2020

Original Research

An Iron Metabolism-Related SLC22A17 for the Prognostic Value of Gastric Cancer

Wei J, Gao X, Qin Y, Liu T, Kang Y

OncoTargets and Therapy 2020, 13:12763-12775

Published Date: 14 December 2020

Original Research

UBE2N Regulates Paclitaxel Sensitivity of Ovarian Cancer via Fos/P53 Axis

Zhu Q, Chen J, Pan P, Lin F, Zhang X

OncoTargets and Therapy 2020, 13:12751-12761

Published Date: 14 December 2020

Original Research

The Role of CCL20-CCR6 Axis in Ovarian Cancer Metastasis

Liu W, Wang W, Zhang N, Di W

OncoTargets and Therapy 2020, 13:12739-12750

Published Date: 11 December 2020

Retraction

lncRNA MAFG-AS1 Contributes to Esophageal Squamous-Cell Carcinoma Progression via Regulating miR143/LASP1 [Retraction]

Qu Y, Liu J

OncoTargets and Therapy 2020, 13:12737-12738

Published Date: 11 December 2020

Original Research

MAGOH/MAGOHB Inhibits the Tumorigenesis of Gastric Cancer via Inactivation of b-RAF/MEK/ERK Signaling

Zhou Y, Li Z, Wu X, Tou L, Zheng J, Zhou D

OncoTargets and Therapy 2020, 13:12723-12735

Published Date: 10 December 2020

Retraction

lncRNA CRNDE is Upregulated in Glioblastoma Multiforme and Facilitates Cancer Progression Through Targeting miR-337-3p and ELMOD2 Axis [Retraction]

Gao J, Chen Q, Zhao Y, Hou R

OncoTargets and Therapy 2020, 13:12721-12722

Published Date: 10 December 2020

Review

Locally Advanced Pancreatic Ductal Adenocarcinoma: Challenges and Progress

Barcellini A, Peloso A, Pugliese L, Vitolo V, Cobianchi L

OncoTargets and Therapy 2020, 13:12705-12720

Published Date: 10 December 2020

Original Research

In vitro and in vivo Study of a Novel Liposome-Mediated Dual Drug Delivery for Synergistic Lung Cancer Therapy via Oral Administration

Zhou Q, Fu Z

OncoTargets and Therapy 2020, 13:12695-12703

Published Date: 10 December 2020

Original Research

Safety and Efficacy of Camrelizumab Combined with Apatinib for Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus: A Multicenter Retrospective Study

Yuan G, Cheng X, Li Q, Zang M, Huang W, Fan W, Wu T, Ruan J, Dai W, Yu W, Chen M, Guo Y, Hu X, Chen J

OncoTargets and Therapy 2020, 13:12683-12693

Published Date: 9 December 2020

Original Research

Prognostic Value of the Preoperative Lymphocyte-to-C-Reactive Protein Ratio and Albumin-to-Globulin Ratio in Patients with Osteosarcoma

Hu H, Deng X, Song Q, Lv H, Chen W, Xing X, Zhu J, Tan Z, Cheng X, Wang B, Shao Z, Zhang Y

OncoTargets and Therapy 2020, 13:12673-12681

Published Date: 9 December 2020

Case report

Next Generation Sequencing Reveals a Synchronous Trilateral Lung Adenocarcinoma Case with Distinct Driver Alterations of EGFR 19 Deletion or EGFR 20 Insertion or EZR-ROS1 Fusion

Zhang X, Feng J, Su X, Lei Y, Wu W, Cheng X

OncoTargets and Therapy 2020, 13:12667-12671

Published Date: 9 December 2020

Original Research

Maintenance Chemotherapy with S-1 Following SOX Regimen Chemotherapy Improves Prognosis of Stage 3 Gastric Cancer After D2 Gastrectomy: A 5-Year Analysis

Tang C, Feng W, Bao Y, Chen C

OncoTargets and Therapy 2020, 13:12661-12666

Published Date: 8 December 2020

Original Research

Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer

Zheng D, Jiang C, Yan N, Miao Y, Wang K, Gao G, Jiao Y, Zhang X, He M, Yang Z

OncoTargets and Therapy 2020, 13:12649-12659

Published Date: 8 December 2020

Original Research

A Circular RNA Derived from Golgi Glycoprotein 1 mRNA Regulates KRAS Expression and Promotes Colorectal Cancer Progression by Targeting microRNA-622

Hao S, Qu R, Hu C, Wang M, Li Y

OncoTargets and Therapy 2020, 13:12637-12648

Published Date: 8 December 2020

Original Research

Superior Effect of the Combination of Carbon-Ion Beam Irradiation and 5-Fluorouracil on Colorectal Cancer Stem Cells in vitro and in vivo

Koom WS, Sai S, Suzuki M, Fujimori A, Yamada S, Tsujii H

OncoTargets and Therapy 2020, 13:12625-12635

Published Date: 8 December 2020

Original Research

CD26 as a Promising Biomarker for Predicting Prognosis in Patients with Pancreatic Tumors

Yan L, Tian X, Ye C, Guan X, Dong B, Zhao M, Wu J, Hao C

OncoTargets and Therapy 2020, 13:12615-12623

Published Date: 8 December 2020

Original Research

KRAS Codon 12 Mutation is Associated with More Aggressive Invasiveness in Synchronous Metastatic Colorectal Cancer (mCRC): Retrospective Research

He K, Wang Y, Zhong Y, Pan X, Si L, Lu J

OncoTargets and Therapy 2020, 13:12601-12613

Published Date: 8 December 2020

Review

Research Progress on the Anti-Cancer Molecular Mechanisms of Huaier

Qi T, Dong Y, Gao Z, Xu J

OncoTargets and Therapy 2020, 13:12587-12599

Published Date: 8 December 2020

Review

The Role of Exosomes in the Female Reproductive System and Breast Cancers

Bai Y, Guo J, Liu Z, Li Y, Jin S, Wang T

OncoTargets and Therapy 2020, 13:12567-12586

Published Date: 8 December 2020

Case report

Success of 125I-Seed Treatment in Vulvar Squamous-Cell Carcinoma with Aplastic Anemia: A Case Report

Ni Q, Pan C, Guo Q, Wang P, Sun G, Xiao S, Dai S

OncoTargets and Therapy 2020, 13:12561-12566

Published Date: 7 December 2020

Original Research

Inhibition of CSRP2 Promotes Leukemia Cell Proliferation and Correlates with Relapse in Adults with Acute Myeloid Leukemia

Wang S, Zhang Y, Liu Y, Zheng R, Wu Z, Fan Y, Li M, Li M, Li T, Li Y, Jiang Z, Wang C, Liu Y

OncoTargets and Therapy 2020, 13:12549-12560

Published Date: 7 December 2020

Original Research

Effect of Dose Adjustments on the Safety and Efficacy of Afatinib in Chinese Patients with EGFR-Mutated Non-Small Cell Lung Cancer Who Participated in the LUX-Lung Clinical Trial Program

Tu HY, Wu YL

OncoTargets and Therapy 2020, 13:12539-12547

Published Date: 7 December 2020

Original Research

Extracellular Matrix–Related Six-lncRNA Signature as a Novel Prognostic Biomarker for Bladder Cancer

Qing L, Gu P, Liu M, Shen J, Liu X, Guang R, Ke K, Huang Z, Lee W, Zhao H

OncoTargets and Therapy 2020, 13:12521-12538

Published Date: 7 December 2020

Case report

STRN-ALK Fusion in Lung Adenocarcinoma with Excellent Response Upon Alectinib Treatment: A Case Report and Literature Review

Su C, Jiang Y, Jiang W, Wang H, Liu S, Shao Y, Zhao W, Ning R, Yu Q

OncoTargets and Therapy 2020, 13:12515-12519

Published Date: 4 December 2020

Original Research

H19 Knockdown Suppresses Proliferation and Induces Apoptosis by Regulating miR-130a-3p/SATB1 in Breast Cancer Cells

Zhong G, Lin Y, Wang X, Wang K, Liu J, Wei W

OncoTargets and Therapy 2020, 13:12501-12513

Published Date: 7 December 2020

Original Research

CBX6 Promotes HCC Metastasis Via Transcription Factors Snail/Zeb1-Mediated EMT Mechanism

Wang J, He H, Jiang Q, Wang Y, Jia S

OncoTargets and Therapy 2020, 13:12489-12500

Published Date: 4 December 2020

Case report

Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepatocellular Carcinoma Patient

Zhang E, Zhang Z, Li J, Huang Z

OncoTargets and Therapy 2020, 13:12477-12487

Published Date: 4 December 2020

Case report

A Partial Response of Pulmonary Pleomorphic Carcinoma to Camrelizumab (PD1 Monoclonal Antibody) Monotherapy: A Case Report

Chen Y, Zhang H, Shi J, Wang T

OncoTargets and Therapy 2020, 13:12471-12476

Published Date: 3 December 2020

Original Research

α-MSH-PE38KDEL Kills Melanoma Cells via Modulating Erk1/2/MITF/TYR Signaling in an MC1R-Dependent Manner

Liu X, Li H, Cong X, Huo D, Cong L, Wu G

OncoTargets and Therapy 2020, 13:12457-12469

Published Date: 3 December 2020

Original Research

Profiling Analysis Reveals the Crucial Role of the Endogenous Peptides in Bladder Cancer Progression

Li W, Zhang Y, Li Y, Cao Y, Zhou J, Sun Z, Wu W, Tan X, Shao Y, Xie K, Yan X

OncoTargets and Therapy 2020, 13:12443-12455

Published Date: 3 December 2020

Review

Physiological and Pathophysiological Roles of Ion Transporter-Mediated Metabolism in the Thyroid Gland and in Thyroid Cancer

Wang H, Ma Z, Cheng X, Tuo B, Liu X, Li T

OncoTargets and Therapy 2020, 13:12427-12441

Published Date: 3 December 2020

Case report

A Case of Tuberous Sclerosis Complex with Lymphangioleiomyomatosis and Renal Cell Carcinoma

Wu Y, Li H, Yu X, Lin M, Chen Y

OncoTargets and Therapy 2020, 13:12421-12426

Published Date: 2 December 2020

Original Research

ADORA1 Promotes Hepatocellular Carcinoma Progression via PI3K/AKT Pathway

Ni S, Wei Q, Yang L

OncoTargets and Therapy 2020, 13:12409-12419

Published Date: 1 December 2020

Original Research

TRPS1 and YAP1 Regulate Cell Proliferation and Drug Resistance of Osteosarcoma via Competitively Binding to the Target of circTADA2A – miR-129-5p

Zhang J, Ma X, Zhou R, Zhou Y

OncoTargets and Therapy 2020, 13:12397-12407

Published Date: 1 December 2020

Original Research

CCNB1 Expedites the Progression of Cervical Squamous Cell Carcinoma via the Regulation by FOXM1

Li S, Liu N, Piao J, Meng F, Li Y

OncoTargets and Therapy 2020, 13:12383-12395

Published Date: 1 December 2020

Review

Impact of Mutational Profile on the Management of Myeloproliferative Neoplasms: A Short Review of the Emerging Data

Loscocco GG, Guglielmelli P, Vannucchi AM

OncoTargets and Therapy 2020, 13:12367-12382

Published Date: 1 December 2020

Corrigendum

Downregulation of miR-575 Inhibits the Tumorigenesis of Gallbladder Cancer via Targeting P27 Kip1 [Corrigendum]

Qin Y, Mi W, Huang C, Li J, Zhang Y, Fu Y

OncoTargets and Therapy 2020, 13:12365-12366

Published Date: 1 December 2020

Case Series

Improvement in Pituitary Imaging After Targeted Therapy in Three Children with BRAF-Mutated Langerhans Cell Histiocytosis with Pituitary Involvement

Yang Y, Wang D, Li N, Ma H, Lian H, Cui L, Zhang Q, Zhao X, Zhang L, Zhao Y, Wang C, Zhang L, Wang T, Li Z, Zhang R

OncoTargets and Therapy 2020, 13:12357-12363

Published Date: 1 December 2020

Original Research

Identification of a Functional ceRNA Network to Explore Potential Biomarkers for Hepatocellular Carcinoma

Jiang Z, Zhang Y, Liu X, Liang J, Qiu G, Zhu X, Chen J, Li L

OncoTargets and Therapy 2020, 13:12341-12355

Published Date: 1 December 2020

Original Research

Raltitrexed Enhances the Antitumor Effect of Apatinib in Human Esophageal Squamous Carcinoma Cells via Akt and Erk Pathways

Zhen H, Li G, Zhao P, Zhang Y, Wang J, Yu J, Cao B

OncoTargets and Therapy 2020, 13:12325-12339

Published Date: 1 December 2020

Original Research

A Study of hTERT Promoter Methylation in Circulating Tumour DNAs of Patients with Ovarian Magnificent Tumour

Li S, Huang W, Li Y, Chen B, Li D

OncoTargets and Therapy 2020, 13:12317-12323

Published Date: 1 December 2020

Review

Review of Adjuvant Therapies in Renal Cell Carcinoma: Evidence to Date

Tacconi EMC, Tuthill M, Protheroe A

OncoTargets and Therapy 2020, 13:12301-12316

Published Date: 30 November 2020

Original Research

Oncogenic Role of NUPR1 in Ovarian Cancer

Yu J, Zhu H, Li R, Jiang Q, Luan W, Shi J, Liu P

OncoTargets and Therapy 2020, 13:12289-12300

Published Date: 30 November 2020

Original Research

Genetic Variability in the microRNA Binding Sites of BMPR1B, TGFBR1, IQGAP1, KRAS, SETD8 and RYR3 and Risk of Breast Cancer in Colombian Women

Garcia Mesa K, Bermejo JL, Torres D, Gilbert M, Plass C, Hamann U

OncoTargets and Therapy 2020, 13:12281-12287

Published Date: 30 November 2020

Original Research

miR-let-7a-5p Inhibits Invasion and Migration of Hepatoma Cells by Regulating BZW2 Expression

Liu L, Zhao J, Peng Y, Yang M, Zhang L, Jin X

OncoTargets and Therapy 2020, 13:12269-12279

Published Date: 27 November 2020

Original Research

MRPL13 is a Prognostic Cancer Biomarker and Correlates with Immune Infiltrates in Breast Cancer

Tao Z, Suo H, Zhang L, Jin Z, Wang Z, Wang D, Wu M, Peng N, Zhao Y, Chen B

OncoTargets and Therapy 2020, 13:12255-12268

Published Date: 27 November 2020

Corrigendum

IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells [Corrigendum]

Li Y, Chen G, Han Z, Cheng H, Qiao L, Li Y

OncoTargets and Therapy 2020, 13:12253-12254

Published Date: 27 November 2020

Review

Research Progress of Cancer Stem Cells in Uveal Melanoma

Chen YN, Li Y, Wei WB

OncoTargets and Therapy 2020, 13:12243-12252

Published Date: 27 November 2020

Original Research

The Immunostimulative Effect and Mechanisms of a Novel Mouse Anti-Human PD-1 Monoclonal Antibody on Jurkat Lymphocytic Cells Cocultured with Hepatoma Cells

Li Z, Li B, Li L, Wang G, Li Y, Fu R, Ming Y, Ni R, Wang J, Ye G, Chen J

OncoTargets and Therapy 2020, 13:12225-12241

Published Date: 27 November 2020

Original Research

Human Positive Coactivator 4 Affects the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma via the mTOR/P70s6k Signaling Pathway

Su X, Yang Y, Ma L, Luo P, Shen K, Dai H, Jiang Y, Shuai L, Liu Z, You J, Min K, Shi C, Chen Z

OncoTargets and Therapy 2020, 13:12213-12223

Published Date: 26 November 2020

Original Research

miR-424-3p Contributes to the Malignant Progression and Chemoresistance of Gastric Cancer

Li Y, Liu H, Cui Y, Chen H, Cui X, Shao J, Su F, He X

OncoTargets and Therapy 2020, 13:12201-12211

Published Date: 26 November 2020

Retraction

Potential Influences of RNF6 on Prognosis and Metastasis of Colorectal Cancer: A Clinical Analysis [Retraction]

Zhu H, Wang C

OncoTargets and Therapy 2020, 13:12199-12200

Published Date: 26 November 2020

Retraction

lncRNA LSINCT5 Regulates miR-20a-5p/XIAP to Inhibit the Growth and Metastasis of Osteosarcoma Cells [Retraction]

Liao SA, Guan J, Mo H, He JL, Zhan XL

OncoTargets and Therapy 2020, 13:12197-12198

Published Date: 26 November 2020

Retraction

Silencing of Long Non-Coding RNA-HCG18 Inhibits the Tumorigenesis of Gastric Cancer Through Blocking PI3K/Akt Pathway [Retraction]

Ma F, An K, Li Y

OncoTargets and Therapy 2020, 13:12195-12196

Published Date: 26 November 2020

Original Research

SNHG6 Interacted with miR-325-3p to Regulate Cisplatin Resistance of Gastric Cancer by Targeting GITR

Sun T, Li K, Zhu K, Yan R, Dang C, Yuan D

OncoTargets and Therapy 2020, 13:12181-12193

Published Date: 25 November 2020

Original Research

Exosomal Transfer of Macrophage-Derived miR-223 Confers Doxorubicin Resistance in Gastric Cancer

Gao H, Ma J, Cheng Y, Zheng P

OncoTargets and Therapy 2020, 13:12169-12179

Published Date: 25 November 2020

Case Series

Sustained Remission of Relapsed or Refractory Mantle Cell Lymphoma After 4-1BB-Based CD19-Directed CAR-T Therapy

Yang C, Lei W, Xie H, Wu G, Wei J, Liang A, Qian W

OncoTargets and Therapy 2020, 13:12163-12168

Published Date: 25 November 2020

Original Research

Berberine Inhibits Cell Proliferation by Interfering with Wild-Type and Mutant P53 in Human Glioma Cells

Liu Z, Chen Y, Gao H, Xu W, Zhang C, Lai J, Liu X, Sun Y, Huang H

OncoTargets and Therapy 2020, 13:12151-12162

Published Date: 24 November 2020

Original Research

Hepsin Promotes Epithelial–Mesenchymal Transition and Cell Invasion Through the miR-222/PPP2R2A/AKT Axis in Prostate Cancer

Li R, Li J, Yang H, Bai Y, Hu C, Wu H, Jiang H, Wang Q

OncoTargets and Therapy 2020, 13:12141-12149

Published Date: 24 November 2020

Original Research

Diagnostic Value of Serum Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) in Colorectal Cancer

Qiu B, Chu LY, Li XX, Peng YH, Xu YW, Xie JJ, Chen XY

OncoTargets and Therapy 2020, 13:12131-12139

Published Date: 24 November 2020

Review

Anti-Angiogenic Therapy in the Treatment of Non-Small Cell Lung Cancer

Tian W, Cao C, Shu L, Wu F

OncoTargets and Therapy 2020, 13:12113-12129

Published Date: 24 November 2020

Review

Non-Coding RNAs in Diffuse Large B-Cell Lymphoma

Shi Y, Ding D, Qu R, Tang Y, Hao S

OncoTargets and Therapy 2020, 13:12097-12112

Published Date: 24 November 2020

Original Research

Identification and Development of Long Non‐coding RNA Associated Regulatory Network in Pancreatic Adenocarcinoma

Zhu W, Gao W, Deng Y, Yu X, Zhu H

OncoTargets and Therapy 2020, 13:12083-12096

Published Date: 23 November 2020

Original Research

Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer

Luo X, Yue M, Li C, Sun D, Wang L

OncoTargets and Therapy 2020, 13:12067-12081

Published Date: 23 November 2020

Original Research

LncRNA CASC15 is Upregulated in Osteosarcoma Plasma Exosomes and CASC15 Knockdown Inhibits Osteosarcoma Progression by Regulating miR-338-3p/RAB14 Axis

Zhang H, Wang J, Ren T, Huang Y, Yu Y, Chen C, Huang Q, Guo W

OncoTargets and Therapy 2020, 13:12055-12066

Published Date: 23 November 2020

Original Research

MIR155HG Knockdown Inhibited the Progression of Cervical Cancer by Binding SRSF1

Shen L, Li Y, Hu G, Huang Y, Song X, Yu S, Xu X

OncoTargets and Therapy 2020, 13:12043-12054

Published Date: 23 November 2020

Original Research

Long Noncoding RNA HEIH Promotes Proliferation, Migration and Invasion of Retinoblastoma Cells Through miR-194-5p/WEE1 Axis

Gao S, Chu Q, Liu X, Zhao X, Qin L, Li G, Liu Q

OncoTargets and Therapy 2020, 13:12033-12041

Published Date: 23 November 2020

Case report

Case Report: A Metabolic Complete Response to Upfront Osimertinib in a Smoker Non-Small Cell Lung Cancer Patient Harbouring EGFR G719A/V769M Complex Mutation

Simionato F, Calvetti L, Cosci M, Scarparo S, Aprile G

OncoTargets and Therapy 2020, 13:12027-12031

Published Date: 23 November 2020

Original Research

Huaier Suppresses the Hepatocellular Carcinoma Cell Cycle by Regulating Minichromosome Maintenance Proteins

Niu Y, Shan L, Gao H, Zhang C, Qian Z, Wang Z, Xu X, Zhang X, Wang J, Ma L, Chen L, Yu Y

OncoTargets and Therapy 2020, 13:12015-12025

Published Date: 20 November 2020

Original Research

Pretreatment CT-Based Radiomics Signature as a Potential Imaging Biomarker for Predicting the Expression of PD-L1 and CD8+TILs in ESCC

Wen Q, Yang Z, Zhu J, Qiu Q, Dai H, Feng A, Xing L

OncoTargets and Therapy 2020, 13:12003-12013

Published Date: 20 November 2020

Original Research

The Effects of TRAF6 on Growth and Progression in Colorectal Cancer are Regulated by miRNA-140

Zhu G, Cheng Z, Lin C, Wang Q, Huang Y, Zheng W, Yang S, Ye J

OncoTargets and Therapy 2020, 13:11991-12001

Published Date: 20 November 2020

Original Research

Long Intergenic Non-Protein Coding RNA 519 Promotes the Biological Activities of Tongue Squamous Cell Carcinoma by Sponging microRNA-876-3p and Consequently Upregulating MACC1

Liu D, Zhao J, Wang H, Li H, Li Y, Qin W

OncoTargets and Therapy 2020, 13:11975-11990

Published Date: 20 November 2020

Original Research

Histone Demethylase KDM3A Promotes Cervical Cancer Malignancy Through the ETS1/KIF14/Hedgehog Axis

Liu J, Li D, Zhang X, Li Y, Ou J

OncoTargets and Therapy 2020, 13:11957-11973

Published Date: 19 November 2020

Case report

Radiotherapy of Pulmonary Hepatoid Adenocarcinoma with Intrahepatic Hemangioma: A Case Report

Wang W, Li G

OncoTargets and Therapy 2020, 13:11947-11955

Published Date: 19 November 2020

Original Research

MST4 Regulates Epithelial–Mesenchymal Transition of Choriocarcinoma by Mediating TGF-β1 Expression

Yu H, Zhang W, Han P, Yang B, Feng X, Zhou P, Zhu X, Zhou B, Chen W, Qian J, Yu J

OncoTargets and Therapy 2020, 13:11935-11946

Published Date: 19 November 2020

Original Research

Identifying a Potential Key Gene, TIMP1, Associated with Liver Metastases of Uveal Melanoma by Weight Gene Co-Expression Network Analysis

Wang P, Yang X, Zhou N, Wang J, Li Y, Liu Y, Xu X, Wei W

OncoTargets and Therapy 2020, 13:11923-11934

Published Date: 19 November 2020

Original Research

Peripheral Blood Leukocyte N6-methyladenosine is a Noninvasive Biomarker for Non-small-cell Lung Carcinoma

Pei Y, Lou X, Li K, Xu X, Guo Y, Xu D, Yang Z, Xu D, Cui W, Zhang D

OncoTargets and Therapy 2020, 13:11913-11921

Published Date: 19 November 2020

Original Research

Circ_SATB2 Attenuates the Anti-Tumor Role of Celastrol in Non-Small-Cell Lung Carcinoma Through Targeting miR-33a-5p/E2F7 Axis

Liu P, Wang M, Tang W, Li G, Gong N

OncoTargets and Therapy 2020, 13:11899-11912

Published Date: 18 November 2020

Original Research

Hypoxic Tumor-Derived Exosomal Circ0048117 Facilitates M2 Macrophage Polarization Acting as miR-140 Sponge in Esophageal Squamous Cell Carcinoma

Lu Q, Wang X, Zhu J, Fei X, Chen H, Li C

OncoTargets and Therapy 2020, 13:11883-11897

Published Date: 18 November 2020

Review

Emerging Targets of Immunotherapy in Gynecologic Cancer

Cheng H, Zong L, Kong Y, Gu Y, Yang J, Xiang Y

OncoTargets and Therapy 2020, 13:11869-11882

Published Date: 18 November 2020

Original Research

miR-27b Suppresses Tongue Squamous Cell Carcinoma Epithelial–Mesenchymal Transition by Targeting ITGA5

Li T, Wu Q, Liu D, Wang X

OncoTargets and Therapy 2020, 13:11855-11867

Published Date: 17 November 2020

Case report

The Role of Dynamic ctDNA Monitoring During Combination Therapies of BRAF V600E-Mutated Metastatic Colorectal Cancer: A Case Report

Wang Z, Ye CY, Zhou WL, Wang MM, Dai WP, Zheng J, Zang YS

OncoTargets and Therapy 2020, 13:11849-11853

Published Date: 17 November 2020

Original Research

Forkhead Box S1 Inhibits the Progression of Hepatocellular Carcinoma

Lei D, Hu G, Chen Y, Hao T, Gao Y, Luo F

OncoTargets and Therapy 2020, 13:11839-11848

Published Date: 17 November 2020

Original Research

LncRNA HCP5 Promotes Cell Invasion and Migration by Sponging miR-29b-3p in Human Bladder Cancer

Zhao C, Li Y, Hu X, Wang R, He W, Wang L, Qi L, Tong S

OncoTargets and Therapy 2020, 13:11827-11838

Published Date: 17 November 2020

Original Research

Tumor Response to Irinotecan is Associated with IL-10 Expression Level in Metastatic Colorectal Cancer-Results from mCRC Biomarker Study

Chang J, Zhang W, Lin G, Tong D, Zhu D, Zhao J, Yu Q, Huang D, Li W

OncoTargets and Therapy 2020, 13:11819-11826

Published Date: 17 November 2020

Original Research

MiR-1224-5p Activates Autophagy, Cell Invasion and Inhibits Epithelial-to-Mesenchymal Transition in Osteosarcoma Cells by Directly Targeting PLK1 Through PI3K/AKT/mTOR Signaling Pathway

Jin B, Jin D, Zhuo Z, Zhang B, Chen K

OncoTargets and Therapy 2020, 13:11807-11818

Published Date: 17 November 2020

Original Research

ZFAS1 Exerts an Oncogenic Role via Suppressing miR-647 in an m6A-Dependent Manner in Cervical Cancer

Yang Z, Ma J, Han S, Li X, Guo H, Liu D

OncoTargets and Therapy 2020, 13:11795-11806

Published Date: 17 November 2020

Original Research

The Regulatory Mechanism and Biological Significance of Mitochondrial Calcium Uniporter in the Migration, Invasion, Angiogenesis and Growth of Gastric Cancer

Wang X, Song X, Cheng G, Zhang J, Dong L, Bai J, Luo D, Xiong Y, Li S, Liu F, Sun Y, Wang X, Li Y, Huang Y

OncoTargets and Therapy 2020, 13:11781-11794

Published Date: 17 November 2020

Original Research

Simultaneous Treatment with Soluble Forms of GAS1 and PTEN Reduces Invasiveness and Induces Death of Pancreatic Cancer Cells

Daniel-García L, Vergara P, Navarrete A, González RO, Segovia J

OncoTargets and Therapy 2020, 13:11769-11779

Published Date: 17 November 2020

Original Research

Secretory Pathway Kinase FAM20C, a Marker for Glioma Invasion and Malignancy, Predicts Poor Prognosis of Glioma

Du S, Guan S, Zhu C, Guo Q, Cao J, Guan G, Cheng W, Cheng P, Wu A

OncoTargets and Therapy 2020, 13:11755-11768

Published Date: 18 November 2020

Original Research

ATAS Acupuncture Reduces Chemotherapy Induced Fatigue in Breast Cancer Through Regulating ADROA1 Expression: A Randomized Sham-Controlled Pilot Trial

Li YF, Liu DQ, Nie JY, Chen DD, Yan M, Zuo Z, Liu LX, Wang WY, Zhu MS, Li WH

OncoTargets and Therapy 2020, 13:11743-11754

Published Date: 17 November 2020

Retraction

FOXN4 Inhibits Breast Cancer Progression by Direct Activation of P53 [Retraction]

Ye H, Duan M

OncoTargets and Therapy 2020, 13:11741-11742

Published Date: 16 November 2020

Review

Adverse Effects of Immune-Checkpoint Inhibitors in Hepatocellular Carcinoma

Cui TM, Liu Y, Wang JB, Liu LX

OncoTargets and Therapy 2020, 13:11725-11740

Published Date: 16 November 2020

Original Research

The SP1-Induced Long Noncoding RNA, LINC00339, Promotes Tumorigenesis in Colorectal Cancer via the miR-378a-3p/MED19 Axis

Ye H, Li W, Wu K, Liu Y, Lv Y, Zhu Y, Luo H, Cui L

OncoTargets and Therapy 2020, 13:11711-11724

Published Date: 16 November 2020

Original Research

Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells

Zeng Z, Lan J, Lei S, Yang Y, He Z, Xue Y, Chen T

OncoTargets and Therapy 2020, 13:11697-11709

Published Date: 17 November 2020

Case report

Erdheim–Chester Disease and Acute Myeloid Leukemia with Mutated NPM1 in a Patient with Clonal Hematopoiesis: A Case Report

Papageorgiou SG, Divane A, Roumelioti M, Kottaridi C, Bouchla A, Georgakopoulos A, Ieremiadou F, Daraki A, Bazani E, Thomopoulos TP, Chatziioannou S, Mavrogenis A, Panayiotidis P, Panayiotides IG, Pappa V, Foukas PG

OncoTargets and Therapy 2020, 13:11689-11695

Published Date: 16 November 2020

Original Research

Identification and Validation of MSX1 as a Key Candidate for Progestin Resistance in Endometrial Cancer

Yang L, Cui Y, Huang T, Sun X, Wang Y

OncoTargets and Therapy 2020, 13:11669-11688

Published Date: 13 November 2020

Original Research

18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model

Li X, Yin G, Ji W, Liu J, Zhang Y, Wang J, Zhu X, Zhu L, Dai D, Ma W, Xu W

OncoTargets and Therapy 2020, 13:11659-11668

Published Date: 13 November 2020

Review

Emerging Role of Immunotherapy for Colorectal Cancer with Liver Metastasis

Yu X, Zhu L, Liu J, Xie M, Chen J, Li J

OncoTargets and Therapy 2020, 13:11645-11658

Published Date: 13 November 2020

Original Research

Clinical Characteristics and Prognosis of Gastric Cancer Patients with BRCA 1/2 Germline Mutations: Report of Ten Cases and a Literature Review

Halpern N, Grinshpun A, Boursi B, Golan T, Margalit O, Aderka D, Friedman E, Laitman Y, Hubert A, Kadouri L, Hamburger T, Barnes-Kedar I, Levi Z, Ben-Aharon I, Brenner B, Goldberg Y, Peretz T, Shacham-Shmueli E

OncoTargets and Therapy 2020, 13:11637-11644

Published Date: 13 November 2020

Original Research

Down-Regulation of Hypoxia-Inducible Factor-1α and Downstream Glucose Transporter Protein-1 Gene by β-elemene Enhancing the Radiosensitivity of Lung Adenocarcinoma Transplanted Tumor

Wu W, Hu Z, Zhao Q, Zhang X, Zhang H, Wang H, Xue W, Yu L, Duan G

OncoTargets and Therapy 2020, 13:11627-11635

Published Date: 13 November 2020

Case report

Next-Generation Sequencing of Synchronous Multiple Primary Lung Cancers in a Patient with Squamous Cell Carcinoma and Small Cell Lung Cancer

Wu X, Huang W, Geng T, Wei Y

OncoTargets and Therapy 2020, 13:11621-11626

Published Date: 12 November 2020

Original Research

Overexpression of GIHCG is Associated with a Poor Prognosis and Immune Infiltration in Hepatocellular Carcinoma

Xiao S, Huang S, Yang J

OncoTargets and Therapy 2020, 13:11607-11619

Published Date: 12 November 2020

Original Research

Functional Implication of Exosomal miR-217 and miR-23b-3p in the Progression of Prostate Cancer

Zhou C, Chen Y, He X, Zheng Z, Xue D

OncoTargets and Therapy 2020, 13:11595-11606

Published Date: 12 November 2020

Original Research

Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer

Li Y, Tian H, Luo H, Fu J, Jiao Y, Li Y

OncoTargets and Therapy 2020, 13:11583-11594

Published Date: 11 November 2020

Original Research

Identification of Genomic Alterations of Perineural Invasion in Patients with Stage II Colorectal Cancer

Su H, Chang C, Hao J, Xu X, Bao M, Luo S, Zhao C, Liu Q, Wang X, Zhou Z, Zhou H

OncoTargets and Therapy 2020, 13:11571-11582

Published Date: 11 November 2020

Original Research

Low Levels of SPARC are Associated with Tumor Progression and Poor Prognosis in Human Endometrial Carcinoma

Wang L, Wang W, Xu Y, Wang Q

OncoTargets and Therapy 2020, 13:11549-11569

Published Date: 11 November 2020

Original Research

LncRNA CTBP1-AS2 Facilitates Gastric Cancer Progression via Regulating the miR-139-3p/MMP11 Axis

Yang Y, Gao M, Li Y, Li M, Ma Q

OncoTargets and Therapy 2020, 13:11537-11547

Published Date: 10 November 2020

Original Research

Safety and Efficacy of Low-Dosage Apatinib Monotherapy in Advanced Lung Squamous-Cell Carcinoma: A Prospective Cohort Study

Geng Q, Shen H, Zhu W, Lu Y, Wang M, Jiang H, Li D

OncoTargets and Therapy 2020, 13:11529-11535

Published Date: 10 November 2020

Original Research

RHPN2 Promotes Malignant Cell Behaviours in Ovarian Cancer by Activating STAT3 Signalling

Yu F, Qiao P, Yin G, Sun Y, Yu X, Sun X, Chu Y, Wang Y

OncoTargets and Therapy 2020, 13:11517-11527

Published Date: 10 November 2020

Original Research

Cytochrome C Oxidase Assembly Factor 1 Homolog Predicts Poor Prognosis and Promotes Cell Proliferation in Colorectal Cancer by Regulating PI3K/AKT Signaling

Xue Y, Li PD, Tang XM, Yan ZH, Xia SS, Tian HP, Liu ZL, Zhou T, Tang XG, Zhang GJ

OncoTargets and Therapy 2020, 13:11505-11516

Published Date: 10 November 2020

Case report

A Novel ROS1-FBXL17 Fusion Co-Existing with CD74-ROS1 Fusion May Improve Sensitivity to Crizotinib and Prolong Progression-Free Survival of Patients with Lung Adenocarcinoma

Lan S, Li H, Liu Y, Xu J, Huang Z, Yan S, Zhang Q, Cheng Y

OncoTargets and Therapy 2020, 13:11499-11504

Published Date: 10 November 2020

Original Research

CD276 Promotes Vasculogenic Mimicry Formation in Hepatocellular Carcinoma via the PI3K/AKT/MMPs Pathway

Cheng R, Wang B, Cai XR, Chen ZS, Du Q, Zhou LY, Ye JM, Chen YL

OncoTargets and Therapy 2020, 13:11485-11498

Published Date: 10 November 2020

Original Research

Low Level Donor Chimerism of CD19 CAR-T Cells Returned to Complete Donor Chimerism in Patients with Relapse After Allo-Hematopoietic Stem Cell Transplant

Li Q, Mu J, Yuan J, Yang Z, Wang J, Deng Q

OncoTargets and Therapy 2020, 13:11471-11484

Published Date: 9 November 2020

Original Research

Long Noncoding RNA LINC00551 Suppresses Glycolysis and Tumor Progression by Regulating c-Myc-Mediated PKM2 Expression in Lung Adenocarcinoma

Wang L, Wang H, Wu B, Zhang C, Yu H, Li X, Wang Q, Shi X, Fan C, Wang D, Luo J, Yang J

OncoTargets and Therapy 2020, 13:11459-11470

Published Date: 9 November 2020

Original Research

Circ_0110805 Knockdown Enhances Cisplatin Sensitivity and Inhibits Gastric Cancer Progression by miR-299-3p/ENDOPDI Axis

Yang X, Zhang Q, Guan B

OncoTargets and Therapy 2020, 13:11445-11457

Published Date: 6 November 2020

Original Research

Expression Profile of GINS Complex Predicts the Prognosis of Pancreatic Cancer Patients

Bu F, Zhu X, Yi X, Luo C, Lin K, Zhu J, Hu C, Liu Z, Zhao J, Huang C, Zhang W, Huang J

OncoTargets and Therapy 2020, 13:11433-11444

Published Date: 6 November 2020

Original Research

Use of a Novel Thyroid-Stimulating Hormone Model for Predicting the Progression of Hepatocellular Carcinoma

Yu L, Liu X, Jiang Y, Wang X, Wang X, Yang Z

OncoTargets and Therapy 2020, 13:11421-11431

Published Date: 6 November 2020

Original Research

LncRNA SNHG6 Inhibits Apoptosis by Regulating EZH2 Expression via the Sponging of MiR-101-3p in Esophageal Squamous-Cell Carcinoma

Wang J, Yang X, Li R, Zhang R, Hu D, Zhang Y, Gao L

OncoTargets and Therapy 2020, 13:11411-11420

Published Date: 6 November 2020

Original Research

Local Delivery of Minocycline and Vorinostat Targets the Tumor Microenvironment to Inhibit the Recurrence of Glioma

Zhao G, Jia J, Wang L, Zhang Y, Yang H, Lu Y, Yu R, Liu H, Zhu Y

OncoTargets and Therapy 2020, 13:11397-11409

Published Date: 6 November 2020

Original Research

Comprehensive Analysis of Aberrantly Expressed Competitive Endogenous RNA Network and Identification of Prognostic Biomarkers in Pheochromocytoma and Paraganglioma

Wang Z, Li Y, Zhong Y, Wang Y, Peng M

OncoTargets and Therapy 2020, 13:11377-11395

Published Date: 6 November 2020

Original Research

Combining Immunoscore with Clinicopathologic Features in Cholangiocarcinoma: An Influential Prognostic Nomogram

Wu ZY, Shen W, Yue JQ, Yao WY, Liu SL, Jin YP, Dong P, Ma F, Wu XS, Gong W

OncoTargets and Therapy 2020, 13:11359-11376

Published Date: 6 November 2020

Original Research

Knockdown of lncRNA ABHD11-AS1 Suppresses the Tumorigenesis of Pancreatic Cancer via Sponging miR-1231

Liu B, Wang W, Sun S, Ding H, Lan L, Li X, Han S

OncoTargets and Therapy 2020, 13:11347-11358

Published Date: 5 November 2020

Original Research

Gigantol Attenuates the Metastasis of Human Bladder Cancer Cells, Possibly Through Wnt/EMT Signaling

Zhao M, Sun Y, Gao Z, Cui H, Chen J, Wang M, Wang Z

OncoTargets and Therapy 2020, 13:11337-11346

Published Date: 4 November 2020

Original Research

SNHG3 Knockdown Suppresses Proliferation, Migration and Invasion, and Promotes Apoptosis in Non-Small Cell Lung Cancer Through Regulating miR-216a/ZEB1 Axis

Zhao S, Gao X, Zhong C, Li Y, Wang M, Zang S

OncoTargets and Therapy 2020, 13:11327-11336

Published Date: 4 November 2020

Original Research

NCAPG Induces Cell Proliferation in Cardia Adenocarcinoma via PI3K/AKT Signaling Pathway

Zhang X, Wang H, Han Y, Zhu M, Song Z, Zhan D, Jia J

OncoTargets and Therapy 2020, 13:11315-11326

Published Date: 4 November 2020

Original Research

Hsa_circ_0006916 Knockdown Represses the Development of Hepatocellular Carcinoma via Modulating miR-599/SRSF2 Axis

Zhu Z, Shen S, Zhao S, Wang Z

OncoTargets and Therapy 2020, 13:11301-11313

Published Date: 4 November 2020

Original Research

Circ_0057553/miR-515-5p Regulates Prostate Cancer Cell Proliferation, Apoptosis, Migration, Invasion and Aerobic Glycolysis by Targeting YES1

Zhang Y, Shi Z, Li Z, Wang X, Zheng P, Li H

OncoTargets and Therapy 2020, 13:11289-11299

Published Date: 4 November 2020

Original Research

LncRNA RNF144A-AS1 Promotes Bladder Cancer Progression via RNF144A-AS1/miR-455-5p/SOX11 Axis

Bi H, Shang Z, Jia C, Wu J, Cui B, Wang Q, Ou T

OncoTargets and Therapy 2020, 13:11277-11288

Published Date: 4 November 2020

Original Research

miR-1297 Suppresses Osteosarcoma Proliferation and Aerobic Glycolysis by Regulating PFKFB2

Pan X, Li H, Tan J, Weng X, Zhou L, Weng Y, Cao X

OncoTargets and Therapy 2020, 13:11265-11275

Published Date: 3 November 2020

Original Research

LOC441178 Overexpression Inhibits the Proliferation and Migration of Esophageal Carcinoma Cells via Methylation of miR-182

Hu W, Chen Z, Chen J, Cai D, Chen C, Fang T

OncoTargets and Therapy 2020, 13:11253-11263

Published Date: 3 November 2020

Original Research

Upregulated circPDK1 Promotes RCC Cell Migration and Invasion by Regulating the miR-377-3P-NOTCH1 Axis in Renal Cell Carcinoma

Huang Z, Ding Y, Zhang L, He S, Jia Z, Gu C, Wang T, Li H, Li X, Jin Z, Ding Y, Yang J

OncoTargets and Therapy 2020, 13:11237-11252

Published Date: 3 November 2020

Original Research

Role of GLUT-1 in the Upregulation of PD-L1 Expression After Radiotherapy and Association of PD-L1 with Favourable Overall Survival in Hypopharyngeal Cancer

Shen LF, Zhou SH, Guo Y

OncoTargets and Therapy 2020, 13:11221-11235

Published Date: 3 November 2020

Original Research

LncRNA XIST Inhibits the Progression of Oral Squamous Cell Carcinoma via Sponging miR-455-3p/BTG2 Axis

Li Q, Sun Q, Zhu B

OncoTargets and Therapy 2020, 13:11211-11220

Published Date: 3 November 2020

Original Research

Let-7c-5p Inhibits Cell Proliferation and Migration and Promotes Apoptosis via the CTHRC1/AKT/ERK Pathway in Esophageal Squamous Cell Carcinoma

Zheng Y, Luo M, Lü M, Zhou T, Liu F, Guo X, Zhang J, Kang M

OncoTargets and Therapy 2020, 13:11193-11209

Published Date: 2 November 2020

Original Research

Lenvatinib Promotes the Antitumor Effect of Doxorubicin in Anaplastic Thyroid Cancer

Su X, Liu J, Zhang H, Gu Q, Zhou X, Ji M, Yao D

OncoTargets and Therapy 2020, 13:11183-11192

Published Date: 2 November 2020

Case report

A Novel MYH9-RET Fusion Occurrence and EGFR T790M Loss as an Acquired Resistance Mechanism to Osimertinib in a Patient with Lung Adenocarcinoma: A Case Report

Sun Y, Pei L, Luo N, Chen D, Meng L

OncoTargets and Therapy 2020, 13:11177-11181

Published Date: 2 November 2020

Original Research

Identification and Validation of STAT6 as a Prognostic and Predictive Biomarker in Acute Myeloid Leukemia

Liu W, Zhu F, Yan J, Liu Y, Chen C, Zhang K, Zhao X, Chen J

OncoTargets and Therapy 2020, 13:11165-11176

Published Date: 2 November 2020

Original Research

Correlation Between Baseline Serum Tumor Markers and Clinical Characteristic Factors in Patients with Advanced Pancreatic Cancer

Deng G, Yan H, Guo Z, Dai G

OncoTargets and Therapy 2020, 13:11151-11163

Published Date: 2 November 2020

Original Research

The Tumor-Associated Macrophage-M2-Cancer Cell Complex and the Observation of Heterogeneous Modification of the Morphological Structure of Lung Adenocarcinoma

Xiao WH, Yao LP, Li M, Wang M, Wu L, Jiang MF, Ma HF, Li JQ, Chen GR

OncoTargets and Therapy 2020, 13:11139-11149

Published Date: 30 October 2020

Original Research

Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy

Gan L, Ren Y, Lu J, Ma J, Shen X, Zhuang Z

OncoTargets and Therapy 2020, 13:11125-11137

Published Date: 29 October 2020

Original Research

Desmoglein 3 and Keratin 14 for Distinguishing Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma

Dong Y, Li S, Sun X, Wang Y, Lu T, Wo Y, Leng X, Kong D, Jiao W

OncoTargets and Therapy 2020, 13:11111-11124

Published Date: 29 October 2020

Original Research

1, 6-O, O-Diacetylbritannilactone from Inula britannica Induces Anti-Tumor Effect on Oral Squamous Cell Carcinoma via miR-1247-3p/LXRα/ABCA1 Signaling

Zheng S, Li L, Li N, Du Y, Zhang N

OncoTargets and Therapy 2020, 13:11097-11109

Published Date: 29 October 2020

Original Research

Bilirubin Can Be Used as a Prognostic Factor for Lung Adenocarcinoma Patients with EGFR Mutations

Geng Y, Mei Y, Xi Y, Yu J, Meng K, Zhang T, Ma W

OncoTargets and Therapy 2020, 13:11089-11095

Published Date: 29 October 2020

Original Research

Targeting Yes1 Associated Transcriptional Regulator Inhibits Hepatocellular Carcinoma Progression and Improves Sensitivity to Sorafenib: An in vitro and in vivo Study

Guo L, Zheng J, Luo J, Zhang Z, Shao G

OncoTargets and Therapy 2020, 13:11071-11087

Published Date: 29 October 2020

Original Research

The Pseudogene DUXAP8 Promotes Colorectal Cancer Cell Proliferation, Invasion, and Migration by Inducing Epithelial-Mesenchymal Transition Through Interacting with EZH2 and H3K27me3

He W, Yu Y, Huang W, Feng G, Li J

OncoTargets and Therapy 2020, 13:11059-11070

Published Date: 29 October 2020

Original Research

Hsa-MiR-590-3p Promotes the Malignancy Progression of Pancreatic Ductal Carcinoma by Inhibiting the Expression of p27 and PPP2R2A via G1/S Cell Cycle Pathway

Shi X, Sheng W, Jia C, Tang J, Dong M

OncoTargets and Therapy 2020, 13:11045-11058

Published Date: 29 October 2020

Original Research

Therapeutic Potential of Apatinib Against Colorectal Cancer by Inhibiting VEGFR2-Mediated Angiogenesis and β-Catenin Signaling

Cai X, Wei B, Li L, Chen X, Yang J, Li X, Jiang X, Lv M, Li M, Lin Y, Xu Q, Guo W, Gu Y

OncoTargets and Therapy 2020, 13:11031-11044

Published Date: 29 October 2020

Original Research

Metformin Combined with 4SC-202 Inhibited the Migration and Invasion of OSCC via STAT3/TWIST1

He Y, Fan Z, He L, Zhang C, Ping F, Deng M, Liu S, Wang Y, Cheng B, Xia J

OncoTargets and Therapy 2020, 13:11019-11029

Published Date: 29 October 2020

Original Research

Hsa_circRNA_100146 Acts as a Sponge of miR-149-5p in Promoting Bladder Cancer Progression via Regulating RNF2

Wang H, Niu X, Mao F, Liu X, Zhong B, Jiang H, Fu G

OncoTargets and Therapy 2020, 13:11007-11017

Published Date: 29 October 2020

Original Research

Zeaxanthin Induces Apoptosis via ROS-Regulated MAPK and AKT Signaling Pathway in Human Gastric Cancer Cells

Sheng YN, Luo YH, Liu SB, Xu WT, Zhang Y, Zhang T, Xue H, Zuo WB, Li YN, Wang CY, Jin CH

OncoTargets and Therapy 2020, 13:10995-11006

Published Date: 29 October 2020

Original Research

LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling

Wang Q, Liao J, He Z, Su Y, Lin D, Xu L, Xu H, Lin J

OncoTargets and Therapy 2020, 13:10983-10994

Published Date: 28 October 2020

Original Research

Butorphanol Inhibits the Malignant Biological Behaviors of Ovarian Cancer Cells via Down-Regulating the Expression of TMEFF1

Wang B, Li Y, Shen Y, Xu Y, Zhang C

OncoTargets and Therapy 2020, 13:10973-10981

Published Date: 28 October 2020

Original Research

Long-Chain Non-Coding RNA SNHG3 Promotes the Growth of Ovarian Cancer Cells by Targeting miR-339-5p/TRPC3 Axis

Liu EL, Zhou YX, Li J, Zhang DH, Liang F

OncoTargets and Therapy 2020, 13:10959-10971

Published Date: 28 October 2020

Original Research

CircDDX42 Accelerates the Development of Pancreatic Cancer via miR-613/ID4/PI3K/AKT Axis

Yan Z, Yin H, Lin G

OncoTargets and Therapy 2020, 13:10945-10957

Published Date: 28 October 2020

Original Research

Comprehensively Identifying the Key tRNA-Derived Fragments and Investigating Their Function in Gastric Cancer Processes

Dong X, Fan X, He X, Chen S, Huang W, Gao J, Huang Y, Wang H

OncoTargets and Therapy 2020, 13:10931-10943

Published Date: 28 October 2020

Original Research

Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation

Wang S, Wang T, Wang L, Zhong L, Li K

OncoTargets and Therapy 2020, 13:10917-10929

Published Date: 28 October 2020

Original Research

Integrated RNA Sequencing and Single-Cell Mass Cytometry Reveal a Novel Role of LncRNA HOXA-AS2 in Tumorigenesis and Stemness of Hepatocellular Carcinoma

Lu Q, Gao J, Tang S, Li Z, Wang X, Deng C, Hu J, Tao Y, Wang Q

OncoTargets and Therapy 2020, 13:10901-10916

Published Date: 27 October 2020

Original Research

Microarray Expression Profiles and Bioinformatics Analyses Reveal Aberrant Circular RNAs Expression in Bladder Cancer

Yang J, Chen J, Wu S, Fei X, Wang X, Wang K

OncoTargets and Therapy 2020, 13:10889-10899

Published Date: 27 October 2020

Original Research

LINC01572 Regulates Cisplatin Resistance in Gastric Cancer Cells by Mediating miR-497-5p

Song Z, Jia N, Li W, Zhang XY

OncoTargets and Therapy 2020, 13:10877-10887

Published Date: 27 October 2020

Original Research

Yes-Associated Protein Contributes to Cell Proliferation and Migration of Gastric Cancer via Activation of Gli1

Han T, Cheng Z, Xu M, Wang X, Wu J, Fang X

OncoTargets and Therapy 2020, 13:10867-10876

Published Date: 27 October 2020

Review

MicroRNAs: Multifaceted Regulators of Colorectal Cancer Metastasis and Clinical Applications

Wen XQ, Qian XL, Sun HK, Zheng LL, Zhu WQ, Li TY, Hu JP

OncoTargets and Therapy 2020, 13:10851-10866

Published Date: 27 October 2020

Original Research

Prognostic Value of Ki67 in Patients with Stage 1–2 Endometrial Cancer: Validation of the Cut-off Value of Ki67 as a Predictive Factor

Jiang P, Jia M, Hu J, Huang Z, Deng Y, Lai L, Ding S, Hu Z

OncoTargets and Therapy 2020, 13:10841-10850

Published Date: 27 October 2020

Original Research

Dihydroartemisinin Inhibits the Proliferation, Colony Formation and Induces Ferroptosis of Lung Cancer Cells by Inhibiting PRIM2/SLC7A11 Axis

Yuan B, Liao F, Shi ZZ, Ren Y, Deng XL, Yang TT, Li DY, Li RF, Pu DD, Wang YJ, Tan Y, Yang Z, Zhang YH

OncoTargets and Therapy 2020, 13:10829-10840

Published Date: 27 October 2020

Original Research

MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma

Huang G, Chen J, Liu J, Zhang X, Duan H, Fang Q

OncoTargets and Therapy 2020, 13:10817-10828

Published Date: 23 October 2020

Original Research

MicroRNA-16 Inhibits Glioblastoma Growth in Orthotopic Model by Targeting Cyclin D1 and WIP1

Wang H, Pan J, Yu L, Meng L, Liu Y, Chen X

OncoTargets and Therapy 2020, 13:10807-10816

Published Date: 23 October 2020

Original Research

Genotyping on ctDNA Identifies Shifts in Mutation Spectrum Between Newly Diagnosed and Relapse/Refractory DLBCL

Liu H, Yang C, Zhao X, Le J, Wu G, Wei J, Liang Y, Qian W

OncoTargets and Therapy 2020, 13:10797-10806

Published Date: 23 October 2020

Original Research

To Develop and Validate the Combination of RNA Methylation Regulators for the Prognosis of Patients with Gastric Cancer

Zhang J, Piao H, Wang Y, Meng X, Yang D, Zhao Y, Zheng Z

OncoTargets and Therapy 2020, 13:10785-10795

Published Date: 23 October 2020

Original Research

Overexpression of hsa_circ_0001715 is a Potential Diagnostic and Prognostic Biomarker in Lung Adenocarcinoma

Lu G, Cui J, Qian Q, Hou Z, Xie H, Hu W, Hao K, Xia N, Zhang Y

OncoTargets and Therapy 2020, 13:10775-10783

Published Date: 23 October 2020

Original Research

MicroRNA Derived from Circulating Exosomes as Noninvasive Biomarkers for Diagnosing Renal Cell Carcinoma

Xiao CT, Lai WJ, Zhu WA, Wang H

OncoTargets and Therapy 2020, 13:10765-10774

Published Date: 23 October 2020

Corrigendum

PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin [Corrigendum]

Wei L, Li P, Luo Y, Zhang M, Yan T, Yang Y, Han Y, Liu S, Wang E

OncoTargets and Therapy 2020, 13:10763-10764

Published Date: 23 October 2020

Corrigendum

VUp-Regulation of VCAN Promotes the Proliferation, Invasion and Migration and Serves as a Biomarker in Gastric Cancer [Corrigendum]

Cheng Y, Sun H, Wu L, Wu F, Tang W, Wang X, Lv C

OncoTargets and Therapy 2020, 13:10761-10762

Published Date: 22 October 2020

Erratum

GRHL2 Acts as an Anti-Oncogene in Bladder Cancer by Regulating ZEB1 in Epithelial-Mesenchymal Transition (EMT) Process [Erratum]

Shen J, Lv X, Zhang L

OncoTargets and Therapy 2020, 13:10759-10760

Published Date: 22 October 2020

Original Research

Polysaccharides Derived from Saposhnikovia divaricata May Suppress Breast Cancer Through Activating Macrophages

Ding J, Guo Y, Jiang X, Li Q, Li K, Liu M, Fu W, Cao Y

OncoTargets and Therapy 2020, 13:10749-10757

Published Date: 22 October 2020

Original Research

Co-Expression of Stem Cell and Epithelial Mesenchymal Transition Markers in Circulating Tumor Cells of Bladder Cancer Patients

Zhang R, Xia J, Wang Y, Cao M, Jin D, Xue W, Huang Y, Chen H

OncoTargets and Therapy 2020, 13:10739-10748

Published Date: 22 October 2020

Original Research

RTKN2 is Associated with Unfavorable Prognosis and Promotes Progression in Non-Small-Cell Lung Cancer

Ji L, Huang Y, Zhang Y, Peng A, Qin J, Lu S, Huang Y

OncoTargets and Therapy 2020, 13:10729-10738

Published Date: 22 October 2020

Review

Human La Protein: An RNA-Binding Protein Involved in Ovarian Cancer Development and Multidrug Resistance

Huang X, Tang J

OncoTargets and Therapy 2020, 13:10721-10727

Published Date: 22 October 2020

Original Research

The LINC01260 Functions as a Tumor Suppressor via the miR-562/CYLD/NF-κB Pathway in Non-Small Cell Lung Cancer

Chen Y, Lei Y, Lin J, Huang Y, Zhang J, Chen K, Sun S, Lin X

OncoTargets and Therapy 2020, 13:10707-10719

Published Date: 20 October 2020

Original Research

Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway

Liu Y, Yin Z, Lu P, Ma Y, Luo B, Xiang L, Zhang W, He Y, Liang X

OncoTargets and Therapy 2020, 13:10693-10705

Published Date: 20 October 2020

Case report

Great Efficacy of Afatinib in a Patient with Lung Adenocarcinoma Harboring EGFR L833V/H835L Mutations: A Case Report

Long X, Qin T, Lin J

OncoTargets and Therapy 2020, 13:10689-10692

Published Date: 20 October 2020

Original Research

Neuropilin-1 Interacts with Fibronectin-1 to Promote Epithelial–Mesenchymal Transition Progress in Gastric Cancer

Wu C, Zeng M, Liao G, Qian K, Li H

OncoTargets and Therapy 2020, 13:10677-10687

Published Date: 20 October 2020

Original Research

VPS53 Suppresses Malignant Properties in Colorectal Cancer by Inducing the Autophagy Signaling Pathway

Peng H, Zheng J, Su Q, Feng X, Peng M, Gong L, Wu H, Pan X

OncoTargets and Therapy 2020, 13:10667-10675

Published Date: 21 October 2020

Review

Possible Oncogenic Viruses Associated with Lung Cancer

Hu Y, Ren S, He Y, Wang L, Chen C, Tang J, Liu W, Yu F

OncoTargets and Therapy 2020, 13:10651-10666

Published Date: 20 October 2020

Original Research

Long Noncoding RNA CDKN2B-AS1 Facilitates Lung Cancer Development Through Regulating miR-378b/NR2C2

Wang G, Xu G, Wang W

OncoTargets and Therapy 2020, 13:10641-10649

Published Date: 20 October 2020

Original Research

Disulfiram, a Ferroptosis Inducer, Triggers Lysosomal Membrane Permeabilization by Up-Regulating ROS in Glioblastoma

Qiu C, Zhang X, Huang B, Wang S, Zhou W, Li C, Li X, Wang J, Yang N

OncoTargets and Therapy 2020, 13:10631-10640

Published Date: 20 October 2020

Original Research

Highly Sensitive Droplet Digital PCR Method for Detection of de novo EGFR T790M Mutation in Patients with Non-Small Cell Lung Cancer

Wang X, Li X, Guo H, Zhu L, Peng Z, Wang J, Yang F, Guo Y

OncoTargets and Therapy 2020, 13:10621-10630

Published Date: 22 October 2020

Original Research

LINC01436 Promotes the Progression of Gastric Cancer via Regulating miR-513a-5p/APE1 Axis

Lu M, Liu D, Li Y

OncoTargets and Therapy 2020, 13:10607-10619

Published Date: 19 October 2020

Original Research

End Processing Factor APLF Promotes NHEJ Efficiency and Contributes to TMZ- and Ionizing Radiation-Resistance in Glioblastoma Cells

Dong W, Li L, Teng X, Yang X, Si S, Chai J

OncoTargets and Therapy 2020, 13:10593-10605

Published Date: 19 October 2020

Original Research

125I Seed Brachytherapy Combined with Single-Agent Chemotherapy in the Treatment of Non-Small-Cell Lung Cancer in the Elderly: A Valuable Solution

Yue TH, Xing W

OncoTargets and Therapy 2020, 13:10581-10591

Published Date: 16 October 2020

Original Research

Bone Marrow-Derived Myofibroblasts Promote Gastric Cancer Metastasis by Activating TGF-β1 and IL-6/STAT3 Signalling Loop

Wang J, Li Q, Cheng X, Zhang B, Lin J, Tang Y, Li F, Yang CS, Wang TC, Tu S

OncoTargets and Therapy 2020, 13:10567-10580

Published Date: 16 October 2020

Case report

Acute Myeloid Leukemia with NUP98-RARG Gene Fusion Similar to Acute Promyelocytic Leukemia: Case Report and Literature Review

Tao S, Song L, Deng Y, Chen Y, Shi Y, Gan Y, Deng Z, Ding B, He Z, Wang C, Yu L

OncoTargets and Therapy 2020, 13:10559-10566

Published Date: 15 October 2020

Original Research

LncRNA LINC01116 Promotes the Development of Colorectal Cancer by Targeting miR-9-5p/STMN1

Bi C, Cui H, Fan H, Li L

OncoTargets and Therapy 2020, 13:10547-10558

Published Date: 15 October 2020

Original Research

α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway

Wang W, Guo X, Dan H

OncoTargets and Therapy 2020, 13:10535-10546

Published Date: 15 October 2020

Original Research

WDR5 Promotes Proliferation and Correlates with Poor Prognosis in Oesophageal Squamous Cell Carcinoma

Huang D, Chen X, Chen X, Qu Y, Wang Y, Yang Y, Cheng Y

OncoTargets and Therapy 2020, 13:10525-10534

Published Date: 15 October 2020

Original Research

ITPKA1 Promotes Growth, Migration and Invasion of Renal Cell Carcinoma via Activation of mTOR Signaling Pathway

Zhu X, Xu A, Zhang Y, Huo N, Cong R, Ma L, Chu Z, Tang Z, Kang X, Xian S, Xu X

OncoTargets and Therapy 2020, 13:10515-10523

Published Date: 15 October 2020

Review

Novel Therapeutic Strategies for CDK4/6 Inhibitors in Metastatic Castrate-Resistant Prostate Cancer

Kase AM, Copland III JA, Tan W

OncoTargets and Therapy 2020, 13:10499-10513

Published Date: 15 October 2020

Original Research

TAGLN and High-mobility Group AT-Hook 2 (HMGA2) Complex Regulates TGF-β-induced Colorectal Cancer Metastasis

Zhou H, Li L, Xie W, Wu L, Lin Y, He X

OncoTargets and Therapy 2020, 13:10489-10498

Published Date: 15 October 2020

Original Research

MDM2-P53 Signaling Pathway-Mediated Upregulation of CDC20 Promotes Progression of Human Diffuse Large B-Cell Lymphoma

Sun C, Li M, Feng Y, Sun F, Zhang L, Xu Y, Lu S, Zhu J, Huang J, Wang J, Hu Y, Zhang Y

OncoTargets and Therapy 2020, 13:10475-10487

Published Date: 15 October 2020

Original Research

Genetic and Clinical Characterization of HOXB2 in Glioma

Pan X, Liu W, Chai Y, Wang J, Zhang Y

OncoTargets and Therapy 2020, 13:10465-10473

Published Date: 14 October 2020

Original Research

High Expression of CD39 is Associated with Poor Prognosis and Immune Infiltrates in Clear Cell Renal Cell Carcinoma

Wu J, Wang YC, Xu WH, Luo WJ, Wan FN, Zhang HL, Ye DW, Qu YY, Zhu YP

OncoTargets and Therapy 2020, 13:10453-10464

Published Date: 14 October 2020

Case report

Durable Response to Osimertinib in a Chinese Patient with Metastatic Lung Adenocarcinoma Harboring a Rare EGFR L858R/D761Y Compound Mutation

Zhu Y, Tang J, Li X, Qin T, Wei Y

OncoTargets and Therapy 2020, 13:10447-10451

Published Date: 14 October 2020

Review

The Evolving Role of Disulfiram in Radiobiology and the Treatment of Breast Cancer

Wang R, Shen J, Yan H, Gao X, Dong T, Wang P, Zhou J

OncoTargets and Therapy 2020, 13:10441-10446

Published Date: 14 October 2020

Original Research

LncRNA GAS8-AS1 Inhibits Ovarian Cancer Progression Through Activating Beclin1-Mediated Autophagy

Fang YJ, Jiang P, Zhai H, Dong JS

OncoTargets and Therapy 2020, 13:10431-10440

Published Date: 14 October 2020

Original Research

Metformin Increases the Chemosensitivity of Pancreatic Cancer Cells to Gemcitabine by Reversing EMT Through Regulation DNA Methylation of miR-663

Gu Y, Zhang B, Gu G, Yang X, Qian Z

OncoTargets and Therapy 2020, 13:10417-10429

Published Date: 14 October 2020

Original Research

Long Non-Coding RNA NRAD1 and LINC00152 are Highly Expressed and Associated with Prognosis in Patients with Hepatocellular Carcinoma

Wang B, Yang S, Zhao W

OncoTargets and Therapy 2020, 13:10409-10416

Published Date: 14 October 2020

Original Research

Gene Expression Along with Genomic Copy Number Variation and Mutational Analysis Were Used to Develop a 9-Gene Signature for Estimating Prognosis of COAD

Lu Y, Wu S, Cui C, Yu M, Wang S, Yue Y, Liu M, Sun Z

OncoTargets and Therapy 2020, 13:10393-10408

Published Date: 14 October 2020

Case report

Identification of a Novel MPRIP-ROS1 Fusion and Clinical Efficacy of Crizotinib in an Advanced Lung Adenocarcinoma Patient: A Case Report

Shu Y, Li H, Shang H, Chen J, Su X, Le W, Lei Y, Tao L, Zou C, Wu W

OncoTargets and Therapy 2020, 13:10387-10391

Published Date: 13 October 2020

Original Research

Knockdown of lncRNA PCAT1 Enhances Radiosensitivity of Cervical Cancer by Regulating miR-128/GOLM1 Axis

Ge X, Gu Y, Li D, Jiang M, Zhao S, Li Z, Liu S

OncoTargets and Therapy 2020, 13:10373-10385

Published Date: 13 October 2020

Original Research

Hsa_circ_0003645 Promotes Breast Cancer Progression by Regulating miR-139-3p/HMGB1 Axis

Zhang J, Ke S, Zheng W, Zhu Z, Wu Y

OncoTargets and Therapy 2020, 13:10361-10372

Published Date: 13 October 2020

Original Research

Aloperine Exerts Antitumor Effects on Bladder Cancer in vitro

Zhang L, Liang J, Liu X, Wu J, Tan D, Hu W

OncoTargets and Therapy 2020, 13:10351-10360

Published Date: 13 October 2020

Case report

Triple Discordances in Receptor Status During Breast Cancer Local Progression and Metastases: Case Report and Literature Review

Martuszewski A, Paluszkiewicz P, Nowak M, Szewczyk K, Staszek-Szewczyk U

OncoTargets and Therapy 2020, 13:10343-10349

Published Date: 13 October 2020

Case Series

Efficacy and Resistance of ALK Inhibitors in Two Inflammatory Myofibroblastic Tumor Patients with ALK Fusions Assessed by Whole Exome and RNA Sequencing

Zhang C, Wang Z, Zhuang R, Guo X, Feng Y, Shen F, Liu W, Zhang Y, Tong H, Sun W, Liu J, Wang G, Dai C, Lu W, Zhou Y

OncoTargets and Therapy 2020, 13:10335-10342

Published Date: 13 October 2020

Original Research

KCNH3 Predicts Poor Prognosis and Promotes Progression in Ovarian Cancer

Li Z, Huang L, Wei L, Zhang B, Zhong S, Ou Y, Wen C, Huang S

OncoTargets and Therapy 2020, 13:10323-10333

Published Date: 13 October 2020

Original Research

Delicaflavone Reverses Cisplatin Resistance via Endoplasmic Reticulum Stress Signaling Pathway in Non-Small Cell Lung Cancer Cells

Wang X, Chen B, Xu D, Li Z, Sui Y, Lin X

OncoTargets and Therapy 2020, 13:10315-10322

Published Date: 13 October 2020

Original Research

Analysis of Differential Expression Proteins of Paclitaxel-Treated Lung Adenocarcinoma Cell A549 Using Tandem Mass Tag-Based Quantitative Proteomics

Zheng W, Xu S

OncoTargets and Therapy 2020, 13:10297-10313

Published Date: 13 October 2020

Original Research

Study of the Relationship Between Serum Amino Acid Metabolism and Lymph Node Metastasis in Patients with Colorectal Cancer

Liu J, Wang J, Ma X, Feng Y, Chen Y, Wang Y, Xue D, Qiao S

OncoTargets and Therapy 2020, 13:10287-10296

Published Date: 13 October 2020

Original Research

Suppressing UVRAG Induces Radiosensitivity by Triggering Lysosomal Membrane Permeabilization in Hypopharyngeal Squamous Cell Carcinoma

Wang J, Wang X, Liu K, Gu L, Yu L, Han L, Meng Z

OncoTargets and Therapy 2020, 13:10275-10285

Published Date: 13 October 2020

Case report

Downstaging of Recurrent Advanced Hepatocellular Carcinoma After Lenvatinib Treatment: Opportunities or Pitfalls? A Case Report

Liu Z, Fu Z, Li G, Lin D

OncoTargets and Therapy 2020, 13:10267-10273

Published Date: 13 October 2020

Original Research

miR-519d-3p Overexpression Inhibits P38 and PI3K/AKT Pathway via Targeting VEGFA to Attenuate the Malignant Biological Behavior of Non-Small Cell Lung Cancer

Zhang G, Hu Y, Yuan W, Qiu H, Yu H, Du J

OncoTargets and Therapy 2020, 13:10257-10266

Published Date: 12 October 2020

Original Research

Long Non-Coding RNA LINC00511 Accelerates Proliferation and Invasion in Cervical Cancer Through Targeting miR-324-5p/DRAM1 Axis

Zhang X, Wang Y, Zhao A, Kong F, Jiang L, Wang J

OncoTargets and Therapy 2020, 13:10245-10256

Published Date: 12 October 2020

Original Research

NR5A2 Promotes Cell Growth and Resistance to Temozolomide Through Regulating Notch Signal Pathway in Glioma

Yang Q, Deng L, Li J, Miao P, Liu W, Huang Q

OncoTargets and Therapy 2020, 13:10231-10244

Published Date: 12 October 2020

Original Research

LukS-PV Inhibits Hepatocellular Carcinoma Cells Migration via the TNNC1/PI3K/AKT Axis

Ma F, Wang Z, Qiang Y, Xu L, Ding P, Wang Y, Ma X

OncoTargets and Therapy 2020, 13:10221-10230

Published Date: 12 October 2020

Review

Role of Focal Adhesion Kinase in Head and Neck Squamous Cell Carcinoma and Its Therapeutic Prospect

Zhang Y, Sun X

OncoTargets and Therapy 2020, 13:10207-10220

Published Date: 9 October 2020

Review

Alternative Treatment Options in Patients with Colorectal Cancer Who Encounter Fluoropyrimidine-Induced Cardiotoxicity

Saif MW

OncoTargets and Therapy 2020, 13:10197-10206

Published Date: 9 October 2020

Original Research

LINC02738 Participates in the Development of Kidney Cancer Through the miR-20b/Sox4 Axis

Han C, Xu B, Zhou L, Li L, Lu C, Yu GP, Liu YS

OncoTargets and Therapy 2020, 13:10185-10196

Published Date: 9 October 2020

Original Research

Knockdown of LncRNA DLEU2 Inhibits Cervical Cancer Progression via Targeting miR-128-3p

Wang B, Hang J, Li W, Yuan W

OncoTargets and Therapy 2020, 13:10173-10184

Published Date: 9 October 2020

Original Research

Long Non-Coding RNA LINC00662 Regulated Proliferation and Migration by Targeting miR-34a-5p/LMAN2L Axis in Glioma

Geng Y, Wu Y, Xu C, Li T, Zhang L

OncoTargets and Therapy 2020, 13:10161-10172

Published Date: 9 October 2020

Original Research

The Novel Circular RNA Circ-PGAP3 Promotes the Proliferation and Invasion of Triple Negative Breast Cancer by Regulating the miR-330-3p/Myc Axis

He D, Yang X, Kuang W, Huang G, Liu X, Zhang Y

OncoTargets and Therapy 2020, 13:10149-10159

Published Date: 9 October 2020

Case report

Ruxolitinib Plus Decitabine Effectively Treats Myelodysplastic Syndrome/Myeloproliferative Neoplasm, Unclassifiable, by Decreasing the Variant Allele Frequency of KRAS

Luo S, Xu X, Ye X, Zhu X, Wu C, Chen D, Jin J, Zheng Y, Zheng M, Huang J

OncoTargets and Therapy 2020, 13:10143-10148

Published Date: 9 October 2020

Original Research

RNF128 Promotes Malignant Behaviors via EGFR/MEK/ERK Pathway in Hepatocellular Carcinoma

Bai XS, Zhang C, Peng R, Jiang GQ, Jin SJ, Wang Q, Ke AW, Bai DS

OncoTargets and Therapy 2020, 13:10129-10141

Published Date: 9 October 2020

Case report

Successful Management of a ROS1-Rearranged Pulmonary Pleomorphic Carcinoma Using Serial Tyrosine Kinase Inhibitors

Wu CW, Yang CY, Chang YL, Shih JY

OncoTargets and Therapy 2020, 13:10123-10127

Published Date: 9 October 2020

Original Research

A Novel Imidazopyridine Derivative Exhibits Anticancer Activity in Breast Cancer by Inhibiting Wnt/β‑catenin Signaling

He LJ, Yang DL, Chen HY, Huang JH, Zhang YJ, Qin HX, Wang JL, Tang DY, Chen ZZ

OncoTargets and Therapy 2020, 13:10111-10121

Published Date: 9 October 2020

Original Research

Wogonoside Attenuates Cutaneous Squamous Cell Carcinoma by Reducing Epithelial–Mesenchymal Transition/Invasion and Cancer Stem-Like Cell Property

Wang X, Chang Y, Gao M, Zhang F

OncoTargets and Therapy 2020, 13:10097-10109

Published Date: 9 October 2020

Original Research

Circ-ELF2 Acts as a Competing Endogenous RNA to Facilitate Glioma Cell Proliferation and Aggressiveness by Targeting MiR-510-5p/MUC15 Signaling

Zhang W, Xu CM, Guo J, Guo L, Huo H, Wang H

OncoTargets and Therapy 2020, 13:10087-10096

Published Date: 9 October 2020

Original Research

Increased SNX20 and PD-L1 Levels Can Predict the Clinical Response to PD-1 Inhibitors in Lung Adenocarcinoma

Fan L, Li L, Huang C, Huang S, Deng J, Xiong J

OncoTargets and Therapy 2020, 13:10075-10085

Published Date: 9 October 2020

Original Research

Comprehensive Assessment of Plasma Circ_0004771 as a Novel Diagnostic and Dynamic Monitoring Biomarker in Gastric Cancer

Xu Y, Kong S, Qin X, Ju S

OncoTargets and Therapy 2020, 13:10063-10074

Published Date: 8 October 2020

Review

Toll-Like Receptor 9 Agonists in Cancer

Karapetyan L, Luke JJ, Davar D

OncoTargets and Therapy 2020, 13:10039-10061

Published Date: 9 October 2020

Original Research

PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin

Wei L, Li P, Luo Y, Zhang M, Yan T, Yang Y, Han Y, Liu S, Wang E

OncoTargets and Therapy 2020, 13:10025-10037

Published Date: 8 October 2020

Original Research

PTHLH Predicts the Prognosis of Patients with Oral Leukoplakia

Lv Z, Cong R, Li J, Cao K, Bao Q, Li L, Yang F, Yuan J

OncoTargets and Therapy 2020, 13:10013-10023

Published Date: 8 October 2020

Original Research

MBD2 Correlates with a Poor Prognosis and Tumor Progression in Renal Cell Carcinoma

Li L, Li N, Liu N, Huo F, Zheng J

OncoTargets and Therapy 2020, 13:10001-10012

Published Date: 7 October 2020

Original Research

miR-135b-5p Suppresses Androgen Receptor-Enhanced Hepatocellular Carcinoma Cell Proliferation via Regulating the HIF-2α/c-Myc/P27 Signals in vitro

Bao S, Wang C, Jin S, Hu K, Lu J

OncoTargets and Therapy 2020, 13:9991-10000

Published Date: 7 October 2020

Original Research

LncRNA PART1 Exerts Tumor-Suppressive Functions in Tongue Squamous Cell Carcinoma via miR-503-5p

Zhao X, Hong Y, Cheng Q, Guo L

OncoTargets and Therapy 2020, 13:9977-9989

Published Date: 7 October 2020

Original Research

Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy

Hu X, Wang J, Chai J, Yu X, Zhang Y, Feng Y, Qin J, Yu H

OncoTargets and Therapy 2020, 13:9967-9976

Published Date: 7 October 2020

Original Research

miR-525-5p Modulates Proliferation and Epithelial–Mesenchymal Transition of Glioma by Targeting Stat-1

Xie P, Han Q, Liu D, Yao D, Lu X, Wang Z, Zuo X

OncoTargets and Therapy 2020, 13:9957-9966

Published Date: 7 October 2020

Retraction

The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis [Retraction]

Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X

OncoTargets and Therapy 2020, 13:9955-9956

Published Date: 7 October 2020

Retraction

The Potential Tumor Promotional Role of circVAPA in Retinoblastoma via Regulating miR-615-3p and SMARCE1 [Retraction]

Xu Q

OncoTargets and Therapy 2020, 13:9953-9954

Published Date: 7 October 2020

Original Research

USP8 Inhibitor Suppresses HER-2 Positive Gastric Cancer Cell Proliferation and Metastasis via the PI3K/AKT Signaling Pathway

Sun J, Shen D, Zheng Y, Ren H, Liu H, Chen X, Gao Y

OncoTargets and Therapy 2020, 13:9941-9952

Published Date: 6 October 2020

Original Research

Long Non-Coding RNA NCK1-AS1 Serves an Oncogenic Role in Gastric Cancer by Regulating miR-137/NUP43 Axis

Li W, Duan J, Shi W, Lei L, Lv P

OncoTargets and Therapy 2020, 13:9929-9939

Published Date: 6 October 2020

Original Research

Linc01094 Accelerates the Growth and Metastatic-Related Traits of Glioblastoma by Sponging miR-126-5p

Li XX, Yu Q

OncoTargets and Therapy 2020, 13:9917-9928

Published Date: 6 October 2020

Original Research

Exploring DNA Methylation Profiles Altered in Cryptogenic Hepatocellular Carcinomas by High-Throughput Targeted DNA Methylation Sequencing: A Preliminary Study for Cryptogenic Hepatocellular Carcinoma

Wang X, Cheng Y, Yan LL, An R, Wang XY, Wang HY

OncoTargets and Therapy 2020, 13:9901-9916

Published Date: 6 October 2020

Original Research

LncRNA MIR194-2HG Promotes Cell Proliferation and Metastasis via Regulation of miR-1207-5p/TCF19/Wnt/β-Catenin Signaling in Liver Cancer

Xu G, Zhu Y, Liu H, Liu Y, Zhang X

OncoTargets and Therapy 2020, 13:9887-9899

Published Date: 6 October 2020

Original Research

Exosomal miR-548c-5p Regulates Colorectal Cancer Cell Growth and Invasion Through HIF1A/CDC42 Axis

Yan S, Ren X, Yang J, Wang J, Zhang Q, Xu D

OncoTargets and Therapy 2020, 13:9875-9885

Published Date: 5 October 2020

Review

Structural and Functional Overview of TEAD4 in Cancer Biology

Chen M, Huang B, Zhu L, Chen K, Liu M, Zhong C

OncoTargets and Therapy 2020, 13:9865-9874

Published Date: 6 October 2020

Original Research

Anlotinib as Exploratory Therapy for Platinum-Resistant Ovarian Cancer: A Retrospective Study on Efficacy and Safety

Ni J, Cheng X, Chen J, Guo W, Dai Z

OncoTargets and Therapy 2020, 13:9857-9863

Published Date: 5 October 2020

Case report

Efficacy of Pyrotinib in a Heavily Pretreated Patient with Lung Adenocarcinoma Harboring HER2 Amplification and Exon 20 Insertions: A Case Report

Shan J, Ruan J, Tan Y, Yan L, Chen S, Du M, Wang L

OncoTargets and Therapy 2020, 13:9849-9856

Published Date: 2 October 2020

Original Research

Emodin Reverses Gemcitabine Resistance of Pancreatic Cancer Cell Lines Through Inhibition of IKKβ/NF-κB Signaling Pathway

Tong H, Huang Z, Chen H, Zhou B, Liao Y, Wang Z

OncoTargets and Therapy 2020, 13:9839-9848

Published Date: 2 October 2020

Original Research

Prognostic and Therapeutic Significance of Androgen Receptor in Patients with Gastric Cancer

Soleymani Fard S, Yazdanbod M, Sotoudeh M, Bashash D, Mahmoodzadeh H, Saliminejad K, Mousavi SA, Ghaffari SH, Alimoghaddam K

OncoTargets and Therapy 2020, 13:9821-9837

Published Date: 2 October 2020

Original Research

lncRNAHIF1A-AS2 Promotes Renal Carcinoma Cell Proliferation and Migration via miR-130a-5p/ERBB2 Pathway

Zhu Y, Yang Z, Chen H, Pan Y, Gong L, Chen F, Jin X, Wen S, Li Y, Chen G

OncoTargets and Therapy 2020, 13:9807-9820

Published Date: 1 October 2020

Original Research

High Expression of miR-196b Predicts Poor Prognosis in Patients with Ovarian Cancer

Li Y, Li J, Liu Z, Zhang Y

OncoTargets and Therapy 2020, 13:9797-9806

Published Date: 1 October 2020

Original Research

MiRNA505/NET1 Axis Acts as a CD8+ T-TIL Regulator in Non-Small Cell Lung Cancer

Zhu P, Liu Z, Huang H, Zhong C, Zhou Y

OncoTargets and Therapy 2020, 13:9785-9795

Published Date: 1 October 2020

Original Research

LINC01087 is Highly Expressed in Breast Cancer and Regulates the Malignant Behavior of Cancer Cells Through miR-335-5p/Rock1

She JK, Fu DN, Zhen D, Gong GH, Zhang B

OncoTargets and Therapy 2020, 13:9771-9783

Published Date: 30 September 2020

Original Research

Novel lncRNA SFTA1P Promotes Tumor Growth by Down-Regulating miR-4766-5p via PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma

Huang G, Yang Y, Lv M, Huang T, Zhan X, Kang W, Hou J

OncoTargets and Therapy 2020, 13:9759-9770

Published Date: 30 September 2020

Case report

Response to Afatinib in a Patient with NSCLC Harboring Novel EGFR Exon 20 Insertion Mutations

Lin L, Wu X, Yan S, Zhu Y, Yan Z, Lv D, Ge H

OncoTargets and Therapy 2020, 13:9753-9757

Published Date: 30 September 2020

Original Research

Long Non-Coding RNA GATA6-AS1 Sponges miR-324-5p to Inhibit Lung Cancer Cell Proliferation and Invasion

Wang Z, Pan L, Yang L, Lv P, Mai S, Wang Y

OncoTargets and Therapy 2020, 13:9741-9751

Published Date: 30 September 2020

Case Series

Malignant Gastrointestinal Neuroectodermal Tumors: Clinicopathological and Prognostic Features of 96 Patients

Li R, Cao J, Chen L, Cui F, Chen S, Feng Z, Li N

OncoTargets and Therapy 2020, 13:9731-9740

Published Date: 30 September 2020

Original Research

IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells

Li Y, Chen G, Han Z, Cheng H, Qiao L, Li Y

OncoTargets and Therapy 2020, 13:9721-9730

Published Date: 30 September 2020

Original Research

G-MDSCs-Derived Exosomal miRNA-143-3p Promotes Proliferation via Targeting of ITM2B in Lung Cancer

Zhou J, Yao Z, Zheng Z, Yang J, Wang R, Fu S, Pan X, Liu Z, Wu K

OncoTargets and Therapy 2020, 13:9701-9719

Published Date: 30 September 2020

Original Research

Curcumin Negatively Regulates Cigarette Smoke-Induced Renal Cell Carcinoma Epithelial–Mesenchymal Transition Through the ERK5/AP-1 Pathway

Zhang T, Zhao L, Zhang T, Wu W, Liu J, Wang X, Wan Y, Geng H, Sun X, Qian W, Yu D

OncoTargets and Therapy 2020, 13:9689-9700

Published Date: 29 September 2020

Review

Lights and Shade of Next-Generation Pi3k Inhibitors in Chronic Lymphocytic Leukemia

Visentin A, Frezzato F, Severin F, Imbergamo S, Pravato S, Romano Gargarella L, Manni S, Pizzo S, Ruggieri E, Facco M, Brunati AM, Semenzato G, Piazza F, Trentin L

OncoTargets and Therapy 2020, 13:9679-9688

Published Date: 29 September 2020

Original Research

AZIN1-AS1, A Novel Oncogenic LncRNA, Promotes the Progression of Non-Small Cell Lung Cancer by Regulating MiR-513b-5p and DUSP11

Cai Y, Wu Q, Liu Y, Wang J

OncoTargets and Therapy 2020, 13:9667-9678

Published Date: 9 October 2020

Original Research

Efficacy and Safety of Iodine-125 Brachytherapy in the Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Wu C, Li B, Sun G, Peng C, Xiang D

OncoTargets and Therapy 2020, 13:9657-9666

Published Date: 29 September 2020

Original Research

Silencing of Long Non-Coding RNA LINC01106 Suppresses the Proliferation, Migration and Invasion of Endometrial Cancer Cells Through Regulating the miR-449a/MET Axis

Gao X, Yu L, Zhang J, Xue P

OncoTargets and Therapy 2020, 13:9643-9655

Published Date: 29 September 2020

Original Research

Effects of miR-384 and miR-134-5p Acting on YY1 Signaling Transduction on Biological Function of Gastric Cancer Cells

Zhong BZ, Wang Q, Liu F, He JL, Xiong Y, Cao J

OncoTargets and Therapy 2020, 13:9631-9641

Published Date: 29 September 2020

Original Research

The Impact of Smoking on Pulmonary Metastasis in Colorectal Cancer

Makino A, Tsuruta M, Okabayashi K, Ishida T, Shigeta K, Seishima R, Ikebata A, Koishikawa K, Hasegawa H, Shimoda M, Fukunaga K, Betsuyaku T, Kitagawa Y

OncoTargets and Therapy 2020, 13:9623-9629

Published Date: 30 September 2020

Review

Role of miRNA-424 in Cancers

Li S, Wu Y, Zhang J, Sun H, Wang X

OncoTargets and Therapy 2020, 13:9611-9622

Published Date: 28 September 2020

Original Research

MiR-101-3p and Syn-Cal14.1a Synergy in Suppressing EZH2-Induced Progression of Breast Cancer

Jiang H, Li L, Zhang J, Wan Z, Wang Y, Hou J, Yu Y

OncoTargets and Therapy 2020, 13:9599-9609

Published Date: 28 September 2020

Original Research

TP53INP2 Modulates Epithelial-to-Mesenchymal Transition via the GSK-3β/β-Catenin/Snail1 Pathway in Bladder Cancer Cells

Zhou Z, Liu X, Li Y, Li J, Deng W, Zhong J, Chen L, Li Y, Zeng X, Wang G, Zhu J, Fu B

OncoTargets and Therapy 2020, 13:9587-9597

Published Date: 28 September 2020

Review

Circular RNAs and Bladder Cancer

Cai Z, Li H

OncoTargets and Therapy 2020, 13:9573-9586

Published Date: 29 September 2020

Original Research

GRK2 Suppresses Hepatocellular Carcinoma Metastasis and Invasion Through Down-Regulation of Prostaglandin E Receptor 2

Li N, Wu JJ, Chen TT, Li XQ, Du JJ, Shan S, Wei W, Sun WY

OncoTargets and Therapy 2020, 13:9559-9571

Published Date: 28 September 2020

Original Research

Targeted Inhibition of P4HB Promotes Cell Sensitivity to Gemcitabine in Urothelial Carcinoma of the Bladder

Wang X, Bai Y, Zhang F, Yang Y, Feng D, Li A, Yang Z, Li D, Tang Y, Wei X, Wei W, Han P

OncoTargets and Therapy 2020, 13:9543-9558

Published Date: 28 September 2020

Original Research

Clinical and Molecular Characterization of Incidentally Discovered Lower-Grade Gliomas with Enrichment of Aerobic Respiration

Wang QW, Wang YW, Wang ZL, Bao ZS, Jiang T, Wang Z, You G

OncoTargets and Therapy 2020, 13:9533-9542

Published Date: 25 September 2020

Original Research

Molecular Analysis of Oncogenic Mutations in Resected Margins by Next-Generation Sequencing Predicts Relapse in Non-Small Cell Lung Cancer Patients

Wei W, Li X, Song M, Wang C

OncoTargets and Therapy 2020, 13:9525-9531

Published Date: 25 September 2020

Original Research

Reduced Expression of hsa-miR-338-3p Contributes to the Development of Glioma Cells by Targeting Mitochondrial 3-Oxoacyl-ACP Synthase (OXSM) in Glioblastoma (GBM)

Wang WY, Lu WC

OncoTargets and Therapy 2020, 13:9513-9523

Published Date: 24 September 2020

Original Research

Circ_0006528 Contributes to Paclitaxel Resistance of Breast Cancer Cells by Regulating miR-1299/CDK8 Axis

Liu G, Zhang Z, Song Q, Guo Y, Bao P, Shui H

OncoTargets and Therapy 2020, 13:9497-9511

Published Date: 24 September 2020

Original Research

Identification of P-Rex1 in the Regulation of Liver Cancer Cell Proliferation and Migration via HGF/c-Met/Akt Pathway

Qiu W, Chang Y, Liu J, Yang X, Yu Y, Li J, Liang Q, Sun G

OncoTargets and Therapy 2020, 13:9481-9495

Published Date: 24 September 2020

Original Research

Saikosaponin D Inhibits Proliferation and Promotes Apoptosis Through Activation of MKK4–JNK Signaling Pathway in Pancreatic Cancer Cells

Lai M, Ge Y, Chen M, Sun S, Chen J, Cheng R

OncoTargets and Therapy 2020, 13:9465-9479

Published Date: 24 September 2020

Original Research

Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells

Yan M, Shen M, Xu L, Huang J, He G, An M, Li X, Gao Z, Meng X

OncoTargets and Therapy 2020, 13:9455-9463

Published Date: 24 September 2020

Original Research

Downregulation of miR-7-5p Inhibits the Tumorigenesis of Esophagus Cancer via Targeting KLF4

Shi W, Song J, Gao Z, Liu X, Wang W

OncoTargets and Therapy 2020, 13:9443-9453

Published Date: 24 September 2020

Original Research

MicroRNA-6071 Suppresses Glioblastoma Progression Through the Inhibition of PI3K/AKT/mTOR Pathway by Binding to ULBP2

Zhou Y, An H, Wu G

OncoTargets and Therapy 2020, 13:9429-9441

Published Date: 23 September 2020

Original Research

Targeting of KDM5A by miR-421 in Human Ovarian Cancer Suppresses the Progression of Ovarian Cancer Cells

Ren F, Shrestha C, Shi H, Sun F, Zhang M, Cao Y, Li G

OncoTargets and Therapy 2020, 13:9419-9428

Published Date: 23 September 2020

Original Research

Relevance of EGFR Between Serum VEGF and MMP-9 in Primary Hepatocellular Carcinoma Patients with Transarterial Chemoembolization

Cao S, Zhu S, Yin W, Xu H, Wu J, Wang Q

OncoTargets and Therapy 2020, 13:9407-9417

Published Date: 23 September 2020

Original Research

The Perspective of Diagnostic and Prognostic Values of Lipoxygenases mRNA Expression in Colon Adenocarcinoma

Ruan GT, Gong YZ, Zhu LC, Gao F, Liao XW, Wang XK, Zhu GZ, Liao C, Wang S, Yan L, Xie HL, Zhou X, Liu JQ, Shao MN, Gan JL

OncoTargets and Therapy 2020, 13:9389-9405

Published Date: 23 September 2020

Original Research

Paclitaxel Suppresses Hepatocellular Carcinoma Tumorigenesis Through Regulating Circ-BIRC6/miR-877-5p/YWHAZ Axis

Liu Y, Guo J, Shen K, Wang R, Chen C, Liao Z, Zhou J

OncoTargets and Therapy 2020, 13:9377-9388

Published Date: 22 September 2020

Original Research

LncRNA MCM3AP-AS1 Promotes Cell Proliferation and Invasion Through Regulating miR-543-3p/SLC39A10/PTEN Axis in Prostate Cancer

Jia Z, Li W, Bian P, Liu H, Pan D, Dou Z

OncoTargets and Therapy 2020, 13:9365-9376

Published Date: 22 September 2020

Original Research

Circular RNA Hsa_circ_0004018 Inhibits Wnt/β-Catenin Signaling Pathway by Targeting microRNA-626/DKK3 in Hepatocellular Carcinoma

Zhu P, Liang H, Huang X, Zeng Q, Liu Y, Lv J, Ming L

OncoTargets and Therapy 2020, 13:9351-9364

Published Date: 22 September 2020

Editorial

Targeting Cancer Stem Cells by Oncolytic Viruses and Nano-Mediated Delivery

Hosseini M, Farassati FS, Farassati F

OncoTargets and Therapy 2020, 13:9349-9350

Published Date: 22 September 2020

Original Research

LncRNA LINC01116 Contributes to Cisplatin Resistance in Lung Adenocarcinoma

Wang J, Gao J, Chen Q, Zou W, Yang F, Wei C, Wang Z

OncoTargets and Therapy 2020, 13:9333-9347

Published Date: 22 September 2020

Review

Potential New Cancer Immunotherapy: Anti-CD47-SIRPα Antibodies

Lu Q, Chen X, Wang S, Lu Y, Yang C, Jiang G

OncoTargets and Therapy 2020, 13:9323-9331

Published Date: 22 September 2020

Review

Advanced Squamous Cell Carcinoma of the Lung: Current Treatment Approaches and the Role of Afatinib

Santos ES, Hart L

OncoTargets and Therapy 2020, 13:9305-9321

Published Date: 22 September 2020

Original Research

MicroRNA-623 Inhibits Epithelial–Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44

Cui D, Wang K, Liu Y, Gao J, Cui J

OncoTargets and Therapy 2020, 13:9291-9303

Published Date: 21 September 2020

Original Research

Downregulation of PFTK1 Inhibits Migration and Invasion of Non-Small Cell Lung Cancer

Jiang M, Chen Q, Zhao X, Teng Y, Yin C, Yue W

OncoTargets and Therapy 2020, 13:9281-9289

Published Date: 22 September 2020

Original Research

Rab14 Overexpression Promotes Proliferation and Invasion Through YAP Signaling in Non-Small Cell Lung Cancers

Zhang J, Zhao X, Luan Z, Wang A

OncoTargets and Therapy 2020, 13:9269-9280

Published Date: 18 September 2020

Original Research

Crosstalk Between AR and Wnt Signaling Promotes Castration-Resistant Prostate Cancer Growth

Luo J, Wang D, Wan X, Xu Y, Lu Y, Kong Z, Li D, Gu W, Wang C, Li Y, Ji C, Gu S, Xu Y

OncoTargets and Therapy 2020, 13:9257-9267

Published Date: 18 September 2020

Original Research

Circular RNA circNELL2 Acts as the Sponge of miR-127-5p to Promote Esophageal Squamous Cell Carcinoma Progression

Xiong G, Diao D, Lu D, Liu X, Liu Z, Mai S, Feng S, Dong X, Cai K

OncoTargets and Therapy 2020, 13:9245-9255

Published Date: 16 September 2020

Original Research

Galangin (GLN) Suppresses Proliferation, Migration, and Invasion of Human Glioblastoma Cells by Targeting Skp2-Induced Epithelial–Mesenchymal Transition (EMT)

Xiong Y, Lai X, Xiang W, Zhou J, Han J, Li H, Deng H, Liu L, Peng J, Chen L

OncoTargets and Therapy 2020, 13:9235-9244

Published Date: 17 September 2020

Original Research

lncRNA CRNDE is Upregulated in Glioblastoma Multiforme and Facilitates Cancer Progression Through Targeting miR-337-3p and ELMOD2 Axis

Gao J, Chen Q, Zhao Y, Hou R

OncoTargets and Therapy 2020, 13:9225-9234

Published Date: 16 September 2020

Original Research

Long Non-Coding RNA LINC01089 Enhances the Development of Gastric Cancer by Sponging miR-145-5p to Mediate SOX9 Expression

Wang F, Yang Q

OncoTargets and Therapy 2020, 13:9213-9224

Published Date: 16 September 2020

Original Research

Long Noncoding RNA PART1 Promotes Hepatocellular Carcinoma Progression via Targeting miR-590-3p/HMGB2 Axis

Pu J, Tan C, Shao Z, Wu X, Zhang Y, Xu Z, Wang J, Tang Q, Wei H

OncoTargets and Therapy 2020, 13:9203-9211

Published Date: 16 September 2020

Original Research

Prognostic Value of the FOXK Family Expression in Patients with Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiotherapy

Zhang Y, Xu M, Chen J, Chen K, Zhuang J, Yang Y, Liu X, Guan G

OncoTargets and Therapy 2020, 13:9185-9201

Published Date: 16 September 2020

Original Research

Mesencephalic Astrocyte-Derived Neurotrophic Factor, a Prognostic Factor of Cholangiocarcinoma, Affects Sorafenib Sensitivity of Cholangiocarcinoma Cells by Deteriorating ER Stress

He J, Li G, Liu X, Ma L, Zhang J, Zheng S, Wang J, Liu J

OncoTargets and Therapy 2020, 13:9169-9184

Published Date: 16 September 2020

Original Research

MicroRNA-182 Promotes Cell Migration by Targeting Programmed Cell Death 4 in Hepatocellular Carcinoma Cells

Hu J, Wang Z, Wang J, Jian Y, Dai J, Wang X, Xiong W

OncoTargets and Therapy 2020, 13:9159-9167

Published Date: 16 September 2020

Original Research

STAT3-Induced Upregulation of lncRNA CASC9 Promotes the Progression of Bladder Cancer by Interacting with EZH2 and Affecting the Expression of PTEN

Yuan B, Sun R, Du Y, Jia Z, Yao W, Yang J

OncoTargets and Therapy 2020, 13:9147-9157

Published Date: 16 September 2020

Original Research

Prognostic Value and Potential Biological Functions of CLDN8 in Patients with Clear Cell Renal Cell Carcinoma

Zhu Z, Xu C, Lin L, Lv T, Cai T, Lin J

OncoTargets and Therapy 2020, 13:9135-9145

Published Date: 15 September 2020

Original Research

PRDX1 is a Tumor Suppressor for Nasopharyngeal Carcinoma by Inhibiting PI3K/AKT/TRAF1 Signaling

Xiao H, Yang T, Yan L, Feng J, Huang B, Jiang Y

OncoTargets and Therapy 2020, 13:9123-9133

Published Date: 15 September 2020

Original Research

The NRF2/KEAP1 Pathway Modulates Nasopharyngeal Carcinoma Cell Radiosensitivity via ROS Elimination

Zhou J, Ding J, Ma X, Zhang M, Huo Z, Yao Y, Li D, Wang Z

OncoTargets and Therapy 2020, 13:9113-9122

Published Date: 11 September 2020

Original Research

HSPA12B Secreted by Tumor-Associated Endothelial Cells Might Induce M2 Polarization of Macrophages via Activating PI3K/Akt/mTOR Signaling

Zhou J, Zhang A, Fan L

OncoTargets and Therapy 2020, 13:9103-9111

Published Date: 11 September 2020

Corrigendum

The Medicinal Fungus Antrodia cinnamomea Regulates DNA Repair and Enhances the Radiosensitivity of Human Esophageal Cancer Cells [Corrigendum]

Liu YM, Liu YK, Wang LW, Huang YC, Huang PI, Tsai TH, Chen YJ

OncoTargets and Therapy 2020, 13:9101-9102

Published Date: 14 September 2020

Original Research

Biological Characterization and Therapeutics for Subscalp Recurrent in Intracranial Glioblastoma

Zhang J, Fang S, Song W, Zhang B, Fan W, Jin G, Liu F

OncoTargets and Therapy 2020, 13:9085-9099

Published Date: 11 September 2020

Review

CircRNAs: A New Chapter in Oral Squamous Cell Carcinoma Biology

Fan H, Jiang J, Tang Y, Liang X, Tang Y

OncoTargets and Therapy 2020, 13:9071-9083

Published Date: 11 September 2020

Original Research

Matrix Metalloproteinase 11 is a Potential Biomarker in Bladder Cancer Diagnosis and Prognosis

Chen C, Liu X, Jiang J, Li S, Wang G, Ju L, Wang F, Liu T, Li S

OncoTargets and Therapy 2020, 13:9059-9069

Published Date: 11 September 2020

Original Research

Prognostic Value of a Nomogram Based on the Dynamic Albumin-to-Alkaline Phosphatase Ratio for Patients with Extensive-Stage Small-Cell Lung Cancer

Li B, Jiang C, Wang R, Zou B, Xie P, Li W, Sun X, Yu J, Wang L

OncoTargets and Therapy 2020, 13:9043-9057

Published Date: 11 September 2020

Original Research

MicroRNA-3666 Suppresses Cell Growth in Head and Neck Squamous Cell Carcinoma Through Inhibition of PFKFB3-Mediated Warburg Effect

Chen L, Cao Y, Wu B, Cao Y

OncoTargets and Therapy 2020, 13:9029-9041

Published Date: 10 September 2020

Original Research

Long Noncoding RNA LINC00525 Promotes the Aggressive Phenotype of Chordoma Through Acting as a microRNA-505-3p Sponge and Consequently Raising HMGB1 Expression

Li L, Lv G, Wang B, Ma H

OncoTargets and Therapy 2020, 13:9015-9027

Published Date: 10 September 2020

Original Research

Caspase Recruitment Domain-Containing Protein 9 Expression is a Novel Prognostic Factor for Lung Adenocarcinoma

Miwa N, Nagano T, Jimbo N, Dokuni R, Kiriu T, Mimura C, Yasuda Y, Katsurada M, Yamamoto M, Tachihara M, Tanaka Y, Kobayashi K, Itoh T, Maniwa Y, Nishimura Y

OncoTargets and Therapy 2020, 13:9005-9013

Published Date: 10 September 2020

Original Research

Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells

Yu Y, Luo Y, Fang Z, Teng W, Yu Y, Tian J, Guo P, Xu R, Wu J, Li Y

OncoTargets and Therapy 2020, 13:8989-9003

Published Date: 10 September 2020

Original Research

Theabrownin Induces Apoptosis and Tumor Inhibition of Hepatocellular Carcinoma Huh7 Cells Through ASK1-JNK-c-Jun Pathway

Xu J, Yan B, Zhang L, Zhou L, Zhang J, Yu W, Dong X, Yao L, Shan L

OncoTargets and Therapy 2020, 13:8977-8987

Published Date: 9 September 2020

Original Research

circKRT7-miR-29a-3p-COL1A1 Axis Promotes Ovarian Cancer Cell Progression

An Q, Liu T, Wang M, Yang Y, Zhang Z, Lin Z, Yang B

OncoTargets and Therapy 2020, 13:8963-8976

Published Date: 9 September 2020

Original Research

Down-Regulation of SREBP via PI3K/AKT/mTOR Pathway Inhibits the Proliferation and Invasion of Non-Small-Cell Lung Cancer Cells

Zhang B, Wu J, Guo P, Wang Y, Fang Z, Tian J, Yu Y, Teng W, Luo Y, Li Y

OncoTargets and Therapy 2020, 13:8951-8961

Published Date: 8 September 2020

Original Research

LncRNA RMRP Promotes Cell Proliferation and Invasion Through miR-613/NFAT5 Axis in Non-Small Cell Lung Cancer

Yang M, Ke H, Zhou W

OncoTargets and Therapy 2020, 13:8941-8950

Published Date: 8 September 2020

Review

Information Transfer and Biological Significance of Neoplastic Exosomes in the Tumor Microenvironment of Osteosarcoma

Pu F, Chen F, Zhang Z, Liu J, Shao Z

OncoTargets and Therapy 2020, 13:8931-8940

Published Date: 8 September 2020

Original Research

Dual-Mode Contrast Agents with RGD-Modified Polymer for Tumour-Targeted US/NIRF Imaging

Nie Z, Luo N, Liu J, Zhang Y, Zeng X, Su D

OncoTargets and Therapy 2020, 13:8919-8929

Published Date: 8 September 2020

Original Research

LncRNA ANCR Suppresses the Progression of Hepatocellular Carcinoma Through the Inhibition of Wnt/β-Catenin Signaling Pathway

Song X, Xu X, Ren X, Ruan X, Wang Y, Yao TT

OncoTargets and Therapy 2020, 13:8907-8917

Published Date: 8 September 2020

Case report

Primary Resistance to Immune Checkpoint Blockade in an STK11/TP53/KRAS-Mutant Lung Adenocarcinoma with High PD-L1 Expression

Kwack WG, Shin SY, Lee SH

OncoTargets and Therapy 2020, 13:8901-8905

Published Date: 7 September 2020

Original Research

Estrogen-Related Receptor α (ERRα) and G Protein-Coupled Estrogen Receptor (GPER) Synergistically Indicate Poor Prognosis in Patients with Triple-Negative Breast Cancer

Ye S, Xu Y, Wang L, Zhou K, He J, Lu J, Huang Q, Sun P, Wang T

OncoTargets and Therapy 2020, 13:8887-8899

Published Date: 7 September 2020

Original Research

Circulating Tie2-Expressing Monocytes: A Potential Biomarker for Cervical Cancer

Han Q, Zhang Q, Ying F, Wang Z, Zhang Y, Gong L, Cai E, Qian J, Cai J

OncoTargets and Therapy 2020, 13:8877-8885

Published Date: 7 September 2020

Original Research

Sodium Butyrate Combined with Docetaxel for the Treatment of Lung Adenocarcinoma A549 Cells by Targeting Gli1

Chen M, Jiang W, Xiao C, Yang W, Qin Q, Mao A, Tan Q, Lian B, Wei C

OncoTargets and Therapy 2020, 13:8861-8875

Published Date: 4 September 2020

Original Research

Combining the Fibrinogen-to-Pre-Albumin Ratio and Prognostic Nutritional Index (FPR-PNI) Predicts the Survival in Elderly Gastric Cancer Patients After Gastrectomy

Zhang X, Zhao W, Chen X, Zhao M, Qi X, Li G, Shen A, Yang L

OncoTargets and Therapy 2020, 13:8845-8859

Published Date: 7 September 2020

Original Research

Lung-molGPA Index Predicts Survival Outcomes of Non-Small-Cell Lung Cancer Patients with Synchronous or Metachronous Brain Metastases

Chen K, Zhang F, Fan Y, Cheng G

OncoTargets and Therapy 2020, 13:8837-8844

Published Date: 4 September 2020

Original Research

TRPM8 Inhibition Regulates the Proliferation, Migration and ROS Metabolism of Bladder Cancer Cells

Wang G, Cao R, Qian K, Peng T, Yuan L, Chen L, Cheng S, Xiong Y, Ju L, Wang X, Xiao Y

OncoTargets and Therapy 2020, 13:8825-8835

Published Date: 4 September 2020

Original Research

Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines

Rodríguez-Lozano DC, Velázquez-Vázquez DE, Del Moral-Morales A, Camacho-Arroyo I

OncoTargets and Therapy 2020, 13:8813-8823

Published Date: 3 September 2020

Original Research

MOB1 Inhibits Malignant Progression of Colorectal Cancer by Targeting PAK2

Liu J, Shi Z, Ma Y, Fu L, Yi M

OncoTargets and Therapy 2020, 13:8803-8811

Published Date: 3 September 2020

Original Research

Genetic Heterogeneity of Esophageal Squamous Cell Carcinoma with Inherited Family History

He W, Leng X, Yang Y, Peng L, Shao Y, Li X, Han Y

OncoTargets and Therapy 2020, 13:8795-8802

Published Date: 3 September 2020

Original Research

RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway

Zhou B, Li C, Yang Y, Wang Z

OncoTargets and Therapy 2020, 13:8783-8794

Published Date: 3 September 2020

Original Research

FAM46B Promotes Apoptosis and Inhibits Glycolysis of Prostate Cancer Through Inhibition of the MYC-LDHA Axis

Liang T, Ye X, Yan D, Deng C, Li Z, Tian B

OncoTargets and Therapy 2020, 13:8771-8782

Published Date: 1 September 2020

Original Research

Serum CXCL13 Level is Associated with Tumor Progression and Unfavorable Prognosis in Penile Cancer

Mo M, Tong S, Li T, Zu X, Hu X

OncoTargets and Therapy 2020, 13:8757-8769

Published Date: 31 August 2020

Case report

Pathological Complete Response from Pyrotinib Combined with Trastuzumab, Paclitaxel and Cisplatin in a Postpartum Woman with HER2-Positive Locally Advanced Breast Cancer: A Case Report

He L, Zhang F, Ma Y, Zuo L, Xu Y

OncoTargets and Therapy 2020, 13:8749-8756

Published Date: 27 August 2020

Original Research

Malic Enzyme 1 Indicates Worse Prognosis in Breast Cancer and Promotes Metastasis by Manipulating Reactive Oxygen Species

Liu C, Cao J, Lin S, Zhao Y, Zhu M, Tao Z, Hu X

OncoTargets and Therapy 2020, 13:8735-8747

Published Date: 26 August 2020

Original Research

Bone Marrow Stromal Antigen 2 is a Potential Unfavorable Prognostic Factor for High-Grade Glioma

Shi H, Luo K, Huang W

OncoTargets and Therapy 2020, 13:8723-8734

Published Date: 26 August 2020

Original Research

Long Noncoding RNA HIF1A-AS2 Promotes Non-Small Cell Lung Cancer Progression by the miR-153-5p/S100A14 Axis

Zhang W, Liu K, Pei Y, Tan J, Ma J, Zhao J

OncoTargets and Therapy 2020, 13:8715-8722

Published Date: 26 August 2020

Original Research

Long-Noncoding RNA PCAT6 Aggravates Osteosarcoma Tumourigenesis via the MiR-143-3p/ZEB1 Axis

Wu K, Feng Q, Li L, Xiong Y, Liu S, Liu J, Wu Q

OncoTargets and Therapy 2020, 13:8705-8714

Published Date: 26 August 2020

Original Research

Effects of Huaier Extract on Ameliorating Colitis-Associated Colorectal Tumorigenesis in Mice

Zou Y, Rong Y, Chen Z, Shen Z, Chen X, Tan Y, Weng J, Huang X, Lin X

OncoTargets and Therapy 2020, 13:8691-8704

Published Date: 26 August 2020

Original Research

The Potential Action of Thomsen–Friedenreich Monoclonal Antibody (A78-G/A7) in Thyroid Cancer

Peng Y, Zhan XX, Cao Y, Zhang HW, Cao WH, Su YJ, Diao C, Sun QM, Cheng RC

OncoTargets and Therapy 2020, 13:8677-8689

Published Date: 25 August 2020

Original Research

VUp-Regulation of VCAN Promotes the Proliferation, Invasion and Migration and Serves as a Biomarker in Gastric Cancer

Cheng Y, Sun H, Wu L, Wu F, Tang W, Wang X, Lv C

OncoTargets and Therapy 2020, 13:8665-8675

Published Date: 25 August 2020

Original Research

Exosomal-lncRNA DLEU1 Accelerates the Proliferation, Migration, and Invasion of Endometrial Carcinoma Cells by Regulating microRNA-E2F3

Jia J, Guo S, Zhang D, Tian X, Xie X

OncoTargets and Therapy 2020, 13:8651-8663

Published Date: 25 August 2020

Original Research

Comprehensive Analysis of circRNA-miRNA-mRNA Network in Cervical Squamous Cell Carcinoma by Integrated Analysis

Wu Q, Liu P, Lao G, Liu Y, Zhang W, Ma C

OncoTargets and Therapy 2020, 13:8641-8650

Published Date: 25 August 2020

Original Research

Cryptanshinone Inhibits the Glycolysis and Inhibits Cell Migration Through PKM2/β-Catenin Axis in Breast Cancer

Zhou J, Su CM, Chen HA, Du S, Li CW, Wu H, Tsai SH, Yeh YT

OncoTargets and Therapy 2020, 13:8629-8639

Published Date: 25 August 2020

Original Research

Circular RNA MYLK Promotes Hepatocellular Carcinoma Progression Through the miR29a/KMT5C Signaling Pathway

Gao J, Li E, Liu W, Yang Q, Xie C, Ai J, Zhou F, Liao W, Wu L

OncoTargets and Therapy 2020, 13:8615-8627

Published Date: 25 August 2020

Original Research

GCNT4 is Associated with Prognosis and Suppress Cell Proliferation in Gastric Cancer

Sun H, Chang J, Ye M, Weng W, Zhang M, Ni S, Tan C, Huang D, Wang L, Du X, Xu M, Sheng W

OncoTargets and Therapy 2020, 13:8601-8613

Published Date: 25 August 2020

Original Research

Targeting PIN-1 Attenuates GCB DLBCL Cell Proliferation Through Inhibition of PI3K/AKT Signaling

Yang H, Zhang P, Li J, Gao Y, Zhao L, Li J, Guo M, Zhang J, Li H, Wang F, Yuan Y

OncoTargets and Therapy 2020, 13:8593-8600

Published Date: 25 August 2020

Original Research

Integrative Genomic Analysis Reveals Cancer-Associated Gene Mutations in Chronic Myeloid Leukemia Patients with Resistance or Intolerance to Tyrosine Kinase Inhibitor

Wu W, Xu N, Zhou X, Liu L, Tan Y, Luo J, Huang J, Qin J, Wang J, Li Z, Yin C, Zhou L, Liu X

OncoTargets and Therapy 2020, 13:8581-8591

Published Date: 25 August 2020

Original Research

CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling

Shao Q, Zhang Z, Cao R, Zang H, Pei W, Sun T

OncoTargets and Therapy 2020, 13:8567-8580

Published Date: 25 August 2020

Case report

A Novel Mutation in MYH Gene Associated with Aggressive Colorectal Cancer in a Child: A Case Report and Review of Literature

Tian X, Wang Q, Cai W

OncoTargets and Therapy 2020, 13:8557-8565

Published Date: 25 August 2020

Original Research

LncRNA SNHG15 Contributes to Immuno-Escape of Gastric Cancer Through Targeting miR141/PD-L1

Dang S, Malik A, Chen J, Qu J, Yin K, Cui L, Gu M

OncoTargets and Therapy 2020, 13:8547-8556

Published Date: 24 August 2020

Original Research

AMPK/mTOR/ULK1 Axis-Mediated Pathway Participates in Apoptosis and Autophagy Induction by Oridonin in Colon Cancer DLD-1 Cells

Bu H, Liu D, Zhang G, Chen L, Song Z

OncoTargets and Therapy 2020, 13:8533-8545

Published Date: 25 August 2020

Original Research

NHE1 Mediates 5-Fu Resistance in Gastric Cancer via STAT3 Signaling Pathway

Sun Z, Luan S, Yao Y, Qin T, Xu X, Shen Z, Yao R, Yue L

OncoTargets and Therapy 2020, 13:8521-8532

Published Date: 24 August 2020

Original Research

Treatment for Liver Tumor Using Combined Transarterial Embolization and Interaarterial Transfecting HIF-1α shRNA in a Rabbit VX2 Model

Guo C, Wang C, Zhang J, Chen X

OncoTargets and Therapy 2020, 13:8511-8519

Published Date: 24 August 2020

Original Research

USP19 Enhances MMP2/MMP9-Mediated Tumorigenesis in Gastric Cancer

Dong Z, Guo S, Wang Y, Zhang J, Luo H, Zheng G, Yang D, Zhang T, Yan L, Song L, Liu K, Sun Z, Meng X, Zheng Z, Zhang J, Zhao Y

OncoTargets and Therapy 2020, 13:8495-8510

Published Date: 24 August 2020

Original Research

Dysregulation of MiR-30a-3p/Gastrin Enhances Tumor Growth and Invasion throughSTAT3/MMP11 Pathway in Gastric Cancer

Liu Y, Gao M, An J, Wang X, Jia Y, Xu J, Zhu J, Cui J, Li W, Xing R, Song L, Liu K, He Y, Sheng J, Qi S, Pan Y, Lu Y

OncoTargets and Therapy 2020, 13:8475-8493

Published Date: 25 August 2020

Original Research

Knockdown of miR-183 Enhances the Cisplatin-Induced Apoptosis in Esophageal Cancer Through Increase of FOXO1 Expression

Chen H, Zheng B, Xue S, Chen C

OncoTargets and Therapy 2020, 13:8463-8474

Published Date: 24 August 2020

Original Research

Prophylactical Low Dose Whole-Liver Irradiation Inhibited Colorectal Liver Metastasis by Regulating Hepatic Niche in Mice

Wang L, Sun Y, Luo X, Han H, Yin H, Zhao B, Chen X, Yu Q, Qiu H, Yuan X

OncoTargets and Therapy 2020, 13:8451-8462

Published Date: 24 August 2020

Original Research

Identification of Long Non-Coding RNA SNHG Family as Promising Prognostic Biomarkers in Acute Myeloid Leukemia

Shi J, Ding W, Lu H

OncoTargets and Therapy 2020, 13:8441-8450

Published Date: 24 August 2020

Original Research

Downregulation of Hsa_circ_0000735 Inhibits the Proliferation, Migration, Invasion, and Glycolysis in Non-small-cell Lung Cancer by Targeting miR-940/BMPER Axis

Huang W, Xu X, Liu M, Cui W, Peng G

OncoTargets and Therapy 2020, 13:8427-8439

Published Date: 24 August 2020

Original Research

Long Noncoding RNA LINC01485 Promotes Tumor Growth and Migration via Inhibiting EGFR Ubiquitination and Activating EGFR/Akt Signaling in Gastric Cancer

Zhou J, Wu L, Li W, Xu X, Ju F, Yu S, Guo J, Li G, Shi J, Zhou S

OncoTargets and Therapy 2020, 13:8413-8425

Published Date: 21 August 2020

Original Research

Identification and Clinical Validation of 4-lncRNA Signature for Predicting Survival in Head and Neck Squamous Cell Carcinoma

Ji Y, Xue Y

OncoTargets and Therapy 2020, 13:8395-8411

Published Date: 21 August 2020

Original Research

TRPV4 Overexpression Promotes Metastasis Through Epithelial–Mesenchymal Transition in Gastric Cancer and Correlates with Poor Prognosis

Wang H, Zhang B, Wang X, Mao J, Li W, Sun Y, Yuan Y, Ben Q, Hua L, Qian A

OncoTargets and Therapy 2020, 13:8383-8394

Published Date: 21 August 2020

Original Research

ADAMTS8 Inhibits Cell Proliferation and Invasion, and Induces Apoptosis in Breast Cancer

Zhang K, Tian R, Wang G, Zhang J, Ma H, Hu X, Xi J, Wang G

OncoTargets and Therapy 2020, 13:8373-8382

Published Date: 21 August 2020

Retraction

Lupeol Inhibits Growth and Migration in Two Human Colorectal Cancer Cell Lines by Suppression of Wnt–β-Catenin Pathway [Retraction]

Wang YH, Hong D, Qian YQ, Tu XZ, Wang KK, Yang XH, Shao SJ, Kong XL, Lou ZF, Jin LJ

OncoTargets and Therapy 2020, 13:8371-8372

Published Date: 20 August 2020

Original Research

lncRNA MAFG-AS1 Contributes to Esophageal Squamous-Cell Carcinoma Progression via Regulating miR143/LASP1

Qu Y, Liu J

OncoTargets and Therapy 2020, 13:8359-8370

Published Date: 20 August 2020

Original Research

Construction of a circRNA-Related ceRNA Prognostic Regulatory Network in Breast Cancer

Song H, Sun J, Kong W, Ji Y, Xu D, Wang J

OncoTargets and Therapy 2020, 13:8347-8358

Published Date: 20 August 2020

Original Research

Prognostic Value of Cumulative Score Based on Preoperative Fibrinogen and Albumin Level in Skull Base Chordoma

Li M, Bai J, Wang S, Zhai Y, Zhang S, Li C, Du J, Zhang Y

OncoTargets and Therapy 2020, 13:8337-8346

Published Date: 20 August 2020

Review

Systemic Approach to Recurrent Primary CNS Lymphoma: Perspective on Current and Emerging Treatment Strategies

Holdhoff M, Wagner-Johnston N, Roschewski M

OncoTargets and Therapy 2020, 13:8323-8335

Published Date: 20 August 2020

Case report

KIF5B-EGFR Fusion: A Novel EGFR Mutation in Lung Adenocarcinoma

Xu H, Shao C

OncoTargets and Therapy 2020, 13:8317-8321

Published Date: 20 August 2020

Case report

Coexisting of COX7A2L–ALK, LINC01210–ALK, ATP13A4–ALK and Acquired SLCO2A1–ALK in a Lung Adenocarcinoma with Rearrangements Loss During the Treatment of Crizotinib and Ceritinib: A Case Report

Cai C, Long Y, Li Y, Huang M

OncoTargets and Therapy 2020, 13:8313-8316

Published Date: 20 August 2020

Original Research

Integrative Analysis of the IQ Motif-Containing GTPase-Activating Protein Family Indicates That the IQGAP3-PIK3C2B Axis Promotes Invasion in Colon Cancer

Liu Z, Li X, Ma J, Li D, Ju H, Liu Y, Chen Y, He X, Zhu Y

OncoTargets and Therapy 2020, 13:8299-8311

Published Date: 20 August 2020

Original Research

Validation of the Prognostic Value of Preoperative Albumin-to-Alkaline Phosphatase Ratio in Patients with Surgically Treated Non-Metastatic Renal Cell Carcinoma

Hu X, Yang ZQ, Dou WC, Shao YX, Wang YH, Lia T, Li X

OncoTargets and Therapy 2020, 13:8287-8297

Published Date: 20 August 2020

Original Research

High PD-L1 Expression is Associated with Unfavorable Clinical Outcome in EGFR-Mutated Lung Adenocarcinomas Treated with Targeted Therapy

Yoon BW, Chang B, Lee SH

OncoTargets and Therapy 2020, 13:8273-8285

Published Date: 20 August 2020

Review

Long Non-Coding RNA BLACAT1 in Human Cancers

Ye T, Yang X, Liu H, Lv P, Ye Z

OncoTargets and Therapy 2020, 13:8263-8272

Published Date: 20 August 2020

Retraction

Overexpression and Clinical Significance of MYC-Associated Zinc Finger Protein in Pancreatic Carcinoma [Retraction]

Zhu X, Luo W, Liang W, Tang F, Bei C, Ren Y, Qin L, Tan C, Zhang Y, Tan S

OncoTargets and Therapy 2020, 13:8261-8262

Published Date: 20 August 2020

Original Research

LINC01089 Blocks the Proliferation and Metastasis of Colorectal Cancer Cells via Regulating miR-27b-3p/HOXA10 Axis

Li M, Guo X

OncoTargets and Therapy 2020, 13:8251-8260

Published Date: 19 August 2020

Case report

Immune Checkpoint Inhibitor Therapy Achieved Complete Response for Drug-Sensitive EGFR/ALK Mutation-Negative Metastatic Pulmonary Large-Cell Neuroendocrine Carcinoma with High Tumor Mutation Burden: A Case Report

Zhang X, Sun Y, Miao Y, Xu S

OncoTargets and Therapy 2020, 13:8245-8250

Published Date: 19 August 2020

Original Research

Circular RNA circEXOC6B Inhibits the Progression of Ovarian Cancer by Sponging miR-421 and Regulating RUS1 Expression

Wang Z, Zhang W, Fang J, Xie P, Miao M, Yang H

OncoTargets and Therapy 2020, 13:8233-8243

Published Date: 19 August 2020

Original Research

Hint1 Overexpression Inhibits the Cell Cycle and Induces Cell Apoptosis in Human Osteosarcoma Cells

Duan DD, Xie H, Shi HF, Huang WW, Ding F, Hong JK, Fan JS, Hu SY, Wang QW, Zhou MQ

OncoTargets and Therapy 2020, 13:8223-8232

Published Date: 19 August 2020

Original Research

lncRNA LSINCT5 Regulates miR-20a-5p/XIAP to Inhibit the Growth and Metastasis of Osteosarcoma Cells

Liao SA, Guan J, Mo H, He JL, Zhan XL

OncoTargets and Therapy 2020, 13:8209-8221

Published Date: 18 August 2020

Original Research

Inhibition of PI3K-AKT Signaling Blocks PGE2-Induced COX-2 Expression in Lung Adenocarcinoma

Yang J, Wang X, Gao Y, Fang C, Ye F, Huang B, Li L

OncoTargets and Therapy 2020, 13:8197-8208

Published Date: 18 August 2020

Original Research

LINC00680 Promotes the Progression of Non-Small Cell Lung Cancer and Functions as a Sponge of miR-410-3p to Enhance HMGB1 Expression

Wang H, Feng L, Zheng Y, Li W, Liu L, Xie S, Zhou Y, Chen C, Cheng D

OncoTargets and Therapy 2020, 13:8183-8196

Published Date: 18 August 2020

Corrigendum

Metformin Promotes Beclin1-Dependent Autophagy to Inhibit the Progression of Gastric Cancer [Corrigendum]

Liu S, Yue C, Chen H, Chen Y, Li G

OncoTargets and Therapy 2020, 13:8181-8182

Published Date: 18 August 2020

Original Research

Reactive Oxygen Species Modulator 1 is Associated with Poor Survival in Patients with Non-Small Cell Lung Cancer After Stereotactic Fractionated Radiosurgery: A Retrospective Pilot Study

Kong M, Sung JY, Lee SH

OncoTargets and Therapy 2020, 13:8173-8180

Published Date: 18 August 2020

Original Research

Inhibition of VEGFA Increases the Sensitivity of Ovarian Cancer Cells to Chemotherapy by Suppressing VEGFA-Mediated Autophagy

Li X, Hu Z, Shi H, Wang C, Lei J, Cheng Y

OncoTargets and Therapy 2020, 13:8161-8171

Published Date: 18 August 2020

Original Research

MiR-140 Resensitizes Cisplatin-Resistant NSCLC Cells to Cisplatin Treatment Through the SIRT1/ROS/JNK Pathway

Lin Z, Pan J, Chen L, Wang X, Chen Y

OncoTargets and Therapy 2020, 13:8149-8160

Published Date: 17 August 2020

Original Research

Fibroblast Activation Protein-α Expressing Fibroblasts Promote Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma

Li F, Wu X, Sun Z, Cai P, Wu L, Li D

OncoTargets and Therapy 2020, 13:8141-8148

Published Date: 14 August 2020

Original Research

Development and Validation of a Novel 8 Immune Gene Prognostic Signature Based on the Immune Expression Profile for Hepatocellular Carcinoma

Xu D, Wang Y, Zhou K, Wu J, Zhang Z, Zhang J, Yu Z, Liu L, Liu X, Li B, Zheng J

OncoTargets and Therapy 2020, 13:8125-8140

Published Date: 14 August 2020

Original Research

A Hybrid Glioma Tumor Cell Lysate Immunotherapy Vaccine Demonstrates Good Clinical Efficacy in the Rat Model

Li XL, Zeng S, He HP, Zeng X, Peng LL, Chen LG

OncoTargets and Therapy 2020, 13:8109-8124

Published Date: 14 August 2020

Original Research

Identification of Osteosarcoma Metastasis-Associated Gene Biomarkers and Potentially Targeted Drugs Based on Bioinformatic and Experimental Analysis

Cao MD, Song YC, Yang ZM, Wang DW, Lin YM, Lu HD

OncoTargets and Therapy 2020, 13:8095-8107

Published Date: 14 August 2020

Original Research

miR-148a Regulates the Stem Cell-Like Side Populations Distribution by Affecting the Expression of ACVR1 in Esophageal Squamous Cell Carcinoma

Tan Y, Lu X, Cheng Z, Pan G, Liu S, Apiziaji P, Wang H, Zhang J, Abulimiti Y

OncoTargets and Therapy 2020, 13:8079-8094

Published Date: 13 August 2020

Original Research

NY-ESO-1 Protein Vaccine Combining Alum, CpG ODN, and HH2 Complex Adjuvant Induces Protective and Therapeutic Anti-Tumor Responses in Murine Multiple Myeloma

Wang H, Huang W, Gao H, Liu TT

OncoTargets and Therapy 2020, 13:8069-8077

Published Date: 13 August 2020

Original Research

Doxorubicin and Edelfosine Combo-Loaded Lipid–Polymer Hybrid Nanoparticles for Synergistic Anticancer Effect Against Drug-Resistant Osteosarcoma

Yang P, Zhang L, Wang T, Liu Q, Wang J, Wang Y, Tu Z, Lin F

OncoTargets and Therapy 2020, 13:8055-8067

Published Date: 12 August 2020

Case report

Metastatic Castration-Resistant Prostate Cancer with Neuroendocrine Transformation and BRCA 1 Germ-Line Mutation: A Case Report and Literature Review

Wu Y, Gao Y, Dou X, Yue J

OncoTargets and Therapy 2020, 13:8049-8054

Published Date: 12 August 2020

Review

Cervical Cancer: Emerging Immune Landscape and Treatment

Guo L, Hua K

OncoTargets and Therapy 2020, 13:8037-8047

Published Date: 12 August 2020

Original Research

Biomarkers of Insulin and the Insulin-Like Growth Factor Axis in Relation to Breast Cancer Risk in Chinese Women

Zhu Y, Wang T, Wu J, Huang O, Zhu L, He J, Li Y, Chen W, Chen X, Shen K

OncoTargets and Therapy 2020, 13:8027-8036

Published Date: 11 August 2020

Original Research

URM1 Promoted Tumor Growth and Suppressed Apoptosis via the JNK Signaling Pathway in Hepatocellular Carcinoma

Cheng X, Zhang Y, Song F, Song F, Gao C, Liang X, Wang F, Chen Z

OncoTargets and Therapy 2020, 13:8011-8025

Published Date: 12 August 2020

Corrigendum

Evaluating the Therapeutic Potential of Zanubrutinib in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma: Evidence to Date [Corrigendum]

Sawalha Y, Bond DA, Alinari L

OncoTargets and Therapy 2020, 13:8009-8010

Published Date: 4 September 2020

Original Research

MiR-654-3p Suppresses Non-Small Cell Lung Cancer Tumourigenesis by Inhibiting PLK4

Pu J, Hu Z, Zhang D, Zhang T, He K, Dai T

OncoTargets and Therapy 2020, 13:7997-8008

Published Date: 13 August 2020

Original Research

miR-133b Suppresses Invasion and Migration of Gastric Cancer Cells via the COL1A1/TGF-β Axis

Guo Y, Lu G, Mao H, Zhou S, Tong X, Wu J, Sun Q, Xu H, Fang F

OncoTargets and Therapy 2020, 13:7985-7995

Published Date: 12 August 2020

Original Research

Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation

Sun J, Shen D, Gao Y, Zheng Y, Zhao L, Maa M, Liu H, Chen X

OncoTargets and Therapy 2020, 13:7973-7984

Published Date: 11 August 2020

Original Research

Next-Generation Sequencing Analysis Identified Genomic Alterations in Pathological Morphologies of 3 Cases of Pulmonary Carcinosarcoma

Li F, Hu S, Kong K, Cao P, Han P, Deng Y, Zhao B

OncoTargets and Therapy 2020, 13:7963-7972

Published Date: 10 August 2020

Original Research

LncRNA TBX5-AS1 Regulates the Tumor Progression Through the PI3K/AKT Pathway in Non-Small Cell Lung Cancer

Qu Q, Jiang S, Li X

OncoTargets and Therapy 2020, 13:7949-7961

Published Date: 12 August 2020

Case report

Three Novel EGFR Mutations (750_758del, I759S, T751_I759delinsS) in One Patient with Metastatic Non-Small Cell Lung Cancer Responding to Osimertinib: A Case Report

Li H, Yu T, Lin Y, Xie Y, Feng J, Huang M, Guo A, Liu X, Yin Z

OncoTargets and Therapy 2020, 13:7941-7948

Published Date: 10 August 2020

Case report

Durable Clinical Response of Advanced Lung Adenocarcinoma Harboring EGFR-19del/T790M/BRAFV600E Mutations After Treating with Osimertinib and Dabrafenib Plus Trametinib: A Case Report

Ding H, Zhuang Z, Xie J, Huang H, Tao Z, Liu Z

OncoTargets and Therapy 2020, 13:7933-7939

Published Date: 10 August 2020

Original Research

miR-137-3p Modulates the Progression of Prostate Cancer by Regulating the JNK3/EZH2 Axis

Zang Y, Zhu J, Li Q, Tu J, Li X, Hu R, Yang D

OncoTargets and Therapy 2020, 13:7921-7932

Published Date: 10 August 2020

Original Research

Antitumorigenic Effect of Hsp90 Inhibitor SNX-2112 on Tongue Squamous Cell Carcinoma is Enhanced by Low-Intensity Ultrasound

Nan C, Zheng Y, Fan H, Sun H, Huang S, Li N

OncoTargets and Therapy 2020, 13:7907-7919

Published Date: 12 August 2020

Original Research

The Long Non-Coding RNA IDH1-AS1 Promotes Prostate Cancer Progression by Enhancing IDH1 Enzyme Activity

Wu S, Ding L, Xu H, Gao J, Shao Y, Zhang S, Wei Z

OncoTargets and Therapy 2020, 13:7897-7906

Published Date: 7 August 2020

Original Research

Long Non-Coding RNA Taurine Upregulated Gene 1 Targets miR-185 to Regulate Cell Proliferation and Glycolysis in Acute Myeloid Leukemia Cells in vitro

Zhang W, Liu Y, Zhang J, Zheng N

OncoTargets and Therapy 2020, 13:7887-7896

Published Date: 7 August 2020

Review

Human Endogenous Retroviruses in Clear Cell Renal Cell Carcinoma: Biological Functions and Clinical Values

Cao W, Kang R, Xiang Y, Hong J

OncoTargets and Therapy 2020, 13:7877-7885

Published Date: 7 August 2020

Original Research

A New Fusion Peptide Targeting Pancreatic Cancer and Inhibiting Tumor Growth

Zheng L, Zhang B, He X, Cao G, Li Y, Cai K, Yang B, Wu Y

OncoTargets and Therapy 2020, 13:7865-7875

Published Date: 12 August 2020

Original Research

Tumor-Derived Exosome-Educated Hepatic Stellate Cells Regulate Lactate Metabolism of Hypoxic Colorectal Tumor Cells via the IL-6/STAT3 Pathway to Confer Drug Resistance

Li F, Zhan L, Dong Q, Wang Q, Wang Y, Li X, Zhang Y, Zhang J

OncoTargets and Therapy 2020, 13:7851-7864

Published Date: 7 August 2020

Original Research

The Potential Tumor Promotional Role of circVAPA in Retinoblastoma via Regulating miR-615-3p and SMARCE1

Xu Q

OncoTargets and Therapy 2020, 13:7839-7849

Published Date: 5 August 2020

Original Research

Huaier Restrains Cholangiocarcinoma Progression in vitro and in vivo Through Modulating lncRNA TP73-AS1 and Inducing Oxidative Stress

Ji D, Zheng W, Huang P, Yao Y, Zhong X, Kang P, Wang Z, Shi G, Xu Y, Cui Y

OncoTargets and Therapy 2020, 13:7819-7837

Published Date: 6 August 2020

Original Research

Serum Exosomal miR-1290 is a Potential Biomarker for Lung Adenocarcinoma

Wu Y, Wei J, Zhang W, Xie M, Wang X, Xu J

OncoTargets and Therapy 2020, 13:7809-7818

Published Date: 5 August 2020

Retraction

lncRNA NEAT1 Facilitates Cell Proliferation, Invasion and Migration by Regulating CBX7 and RTCB in Breast Cancer [Retraction]

Yan L, Zhang Z, Yin X, Li Y

OncoTargets and Therapy 2020, 13:7807-7808

Published Date: 5 August 2020

Original Research

Circ_0005576 Promotes Malignant Progression Through miR-874/CDK8 Axis in Colorectal Cancer

Yu C, Li S, Hu X

OncoTargets and Therapy 2020, 13:7793-7805

Published Date: 5 August 2020

Case report

Pseudoprogression After Palbociclib with Aromatase Inhibitors Treatment in Metastatic Breast Cancer

Huang W, Li C, Chen M, Lin D, Wu F, Chen X, Li N, Wang L, Liu J

OncoTargets and Therapy 2020, 13:7785-7792

Published Date: 5 August 2020

Original Research

Circular RNA ZNF609 Promoted Hepatocellular Carcinoma Progression by Upregulating PAP2C Expression via Sponging miR-342-3p

Liao X, Zhan W, Tian B, Luo Y, Gu F, Li R

OncoTargets and Therapy 2020, 13:7773-7783

Published Date: 4 August 2020

Original Research

Circular RNA circLPAR3 Facilitates Esophageal Squamous Cell Carcinoma Progression Through Upregulating HMGB1 via Sponging miR-375/miR-433

Cheng H, Jiang W, Song Z, Li T, Li Y, Zhang L, Wang G

OncoTargets and Therapy 2020, 13:7759-7771

Published Date: 4 August 2020

Original Research

PKMYT1 Promotes Gastric Cancer Cell Proliferation and Apoptosis Resistance

Zhang QY, Chen XQ, Liu XC, Wu DM

OncoTargets and Therapy 2020, 13:7747-7757

Published Date: 4 August 2020

Original Research

The Somatic Mutation Landscape and RNA Prognostic Markers in Stomach Adenocarcinoma

Zhang X, Zheng P, Li Z, Gao S, Liu G

OncoTargets and Therapy 2020, 13:7735-7746

Published Date: 4 August 2020

Original Research

Radiotherapy Increases 12-LOX and CCL5 Levels in Esophageal Cancer Cells and Promotes Cancer Metastasis via THP-1-Derived Macrophages

Mi S, Qu Y, Chen X, Wen Z, Chen P, Cheng Y

OncoTargets and Therapy 2020, 13:7719-7733

Published Date: 5 August 2020

Review

Long Non-Coding Small Nucleolar RNA Host Genes (SNHGs) in Endocrine-Related Cancers

Qin Y, Sun W, Wang Z, Dong W, He L, Zhang T, Zhang H

OncoTargets and Therapy 2020, 13:7699-7717

Published Date: 5 August 2020

Original Research

Evaluation of Tumor Specificity and Immunity of Thymidine Kinase-Deleted Vaccinia Virus Guang9 Strain

Ding Y, Fan J, Deng L, Peng Y, Zhou B, Huang B

OncoTargets and Therapy 2020, 13:7683-7697

Published Date: 5 August 2020

Case Series

SET-CAN Fusion Gene in Acute Leukemia and Myeloid Neoplasms: Report of Three Cases and a Literature Review

Zhang H, Zhang L, Li Y, Gu H, Wang X

OncoTargets and Therapy 2020, 13:7665-7681

Published Date: 3 August 2020

Original Research

Identification of Critical Pathways and Hub Genes in LanCL1-Overexpressed Prostate Cancer Cells

Tang R, Wu Z, Lu F, Wang C, Wu B, Wang J, Zhu Y

OncoTargets and Therapy 2020, 13:7653-7664

Published Date: 3 August 2020

Original Research

HNF1A-Induced lncRNA HCG18 Facilitates Gastric Cancer Progression by Upregulating DNAJB12 via miR-152-3p

Ma P, Li L, Liu F, Zhao Q

OncoTargets and Therapy 2020, 13:7641-7652

Published Date: 3 August 2020

Original Research

Phosphoribosyl Pyrophosphate Amidotransferase Promotes the Progression of Thyroid Cancer via Regulating Pyruvate Kinase M2

Liu B, Song M, Qin H, Zhang B, Liu Y, Sun Y, Ma Y, Shi T

OncoTargets and Therapy 2020, 13:7629-7639

Published Date: 3 August 2020

Original Research

Long Non-Coding RNA LOXL1-AS1 Enhances Colorectal Cancer Proliferation, Migration and Invasion Through miR-708-5p/CD44-EGFR Axis

Wu X, Cui F, Chen Y, Zhu Y, Liu F

OncoTargets and Therapy 2020, 13:7615-7627

Published Date: 3 August 2020

Case Series

Atypical Mature T-Cell Neoplasms: The Relevance of the Role of Flow Cytometry

Statuto T, D'Auria F, Del Vecchio L, Mansueto GR, Villani O, Lalinga AV, Possidente L, Nozza F, Vona G, Rago L, Storto G, Gasparini VR, Zambello R, D'Arena G, Valvano L

OncoTargets and Therapy 2020, 13:7605-7614

Published Date: 3 August 2020

Case report

Medullary Thyroid Carcinoma in a Patient with MEN 1 Syndrome. Case Report and Literature Review

Friziero A, Da Dalt G, Piotto A, Serafini S, Grego A, Galuppini F, Pennelli G, Sperti C

OncoTargets and Therapy 2020, 13:7599-7603

Published Date: 31 July 2020

Original Research

JuBei Oral Liquid Induces Mitochondria-Mediated Apoptosis in NSCLC Cells

Pan Z, Chen Q, Zheng X, Wang K, Duan Y, Xiao K, Jia Z, Ding X

OncoTargets and Therapy 2020, 13:7585-7598

Published Date: 31 July 2020

Original Research

lncRNA UCA1 Contributes to 5-Fluorouracil Resistance of Colorectal Cancer Cells Through miR-23b-3p/ZNF281 Axis

Xian Z, Hu B, Wang T, Zeng J, Cai J, Zou Q, Zhu P

OncoTargets and Therapy 2020, 13:7571-7583

Published Date: 31 July 2020

Original Research

Long Noncoding RNA LINC00460 Facilitates Colorectal Cancer Progression by Negatively Regulating miR-613

Wang L, Chen X, Sun X, Suo J

OncoTargets and Therapy 2020, 13:7555-7569

Published Date: 3 August 2020

Original Research

Both Methylation and Copy Number Variation Participated in the Varied Expression of PRAME in Multiple Myeloma

Yang L, Dao FT, Chang Y, Wang YZ, Li LD, Chen WM, Long LY, Liu YR, Lu J, Liu KY, Qin YZ

OncoTargets and Therapy 2020, 13:7545-7553

Published Date: 31 July 2020

Original Research

Large-Scale Analysis Reveals the Specific Clinical and Immune Features of DGCR5 in Glioma

Wu X, Hou P, Qiu Y, Wang Q, Lu X

OncoTargets and Therapy 2020, 13:7531-7543

Published Date: 31 July 2020

Original Research

LINC00662 Long Non-Coding RNA Knockdown Attenuates the Proliferation, Migration, and Invasion of Osteosarcoma Cells by Regulating the microRNA-15a-5p/Notch2 Axis

Liu S, Meng X

OncoTargets and Therapy 2020, 13:7517-7530

Published Date: 10 August 2020

Original Research

Cancer-Derived Transforming Growth Factor-β Modulates Tumor-Associated Macrophages in Ampullary Cancer

Cheng LC, Chao YJ, Wang CY, Phan NN, Chen YL, Wang TW, Hsu HP, Lin YJ, Shan YS, Lai MD

OncoTargets and Therapy 2020, 13:7503-7516

Published Date: 3 August 2020

Original Research

MiR-1299 Impedes the Progression of Non-Small-Cell Lung Cancer Through EGFR/PI3K/AKT Signaling Pathway

Cao S, Li L, Li J, Zhao H

OncoTargets and Therapy 2020, 13:7493-7502

Published Date: 30 July 2020

Original Research

miR-106b-5p Inhibits IRF1/IFN-β Signaling to Promote M2 Macrophage Polarization of Glioblastoma

Shi Y, Zhang B, Zhu J, Huang W, Han B, Wang Q, Qi C, Wang M, Liu F

OncoTargets and Therapy 2020, 13:7479-7492

Published Date: 30 July 2020

Original Research

miR-96-5p Suppresses the Progression of Nasopharyngeal Carcinoma by Targeting CDK1

Luo X, He X, Liu X, Zhong L, Hu W

OncoTargets and Therapy 2020, 13:7467-7477

Published Date: 30 July 2020

Review

Clinical Evaluation of the Safety and Efficacy of Trifluridine/Tipiracil in the Treatment of Advanced Gastric/Gastroesophageal Junction Adenocarcinoma: Evidence to Date

Wheelden M, Yee NS

OncoTargets and Therapy 2020, 13:7459-7465

Published Date: 30 July 2020

Original Research

Parthenolide Inhibits Angiogenesis in Esophageal Squamous Cell Carcinoma Through Suppression of VEGF

Tian B, Xiao Y, Ma J, Ou W, Wang H, Wu J, Tang J, Zhang B, Liao X, Yang D, Wu Z, Li X, Zhou Y, Su M, Wang W

OncoTargets and Therapy 2020, 13:7447-7458

Published Date: 29 July 2020

Original Research

Knockdown of T Cell Immunoglobulin and Mucin 1 (Tim-1) Suppresses Glioma Progression Through Inhibition of the Cytokine-PI3K/AKT Pathway

Zhou P, Fei M, Han Y, Zhou M, Wang H

OncoTargets and Therapy 2020, 13:7433-7445

Published Date: 4 August 2020

Original Research

Identification and Validation of Reference Genes Selection in Ovarian Cancer Exposed to Hypoxia

Yan W, Xie M, Li R, Hu H, Tang B, Shen J

OncoTargets and Therapy 2020, 13:7423-7431

Published Date: 28 July 2020

Review

Role of αVβ3 in Prostate Cancer: Metastasis Initiator and Important Therapeutic Target

Tang L, Xu M, Zhang L, Qu L, Liu X

OncoTargets and Therapy 2020, 13:7411-7422

Published Date: 28 July 2020

Original Research

FKBP10 Acts as a New Biomarker for Prognosis and Lymph Node Metastasis of Gastric Cancer by Bioinformatics Analysis and in Vitro Experiments

Gong LB, Zhang C, Yu RX, Li C, Fan YB, Liu YP, Qu XJ

OncoTargets and Therapy 2020, 13:7399-7409

Published Date: 28 July 2020

Original Research

LEMD1-AS1 Suppresses Ovarian Cancer Progression Through Regulating miR-183-5p/TP53 Axis

Guo R, Qin Y

OncoTargets and Therapy 2020, 13:7387-7398

Published Date: 28 July 2020

Original Research

3,6-Disubstituted 1,2,4-Triazolo[3,4-b]Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha

Sagredou S, Dalezis P, Nikoleousakos N, Nikolaou M, Voura M, Almpanakis K, Panayiotidis MI, Sarli V, Trafalis DT

OncoTargets and Therapy 2020, 13:7369-7386

Published Date: 28 July 2020

Original Research

Knockdown of circ_0000512 Inhibits Cell Proliferation and Promotes Apoptosis in Colorectal Cancer by Regulating miR-296-5p/RUNX1 Axis

Wang L, Wu H, Chu F, Zhang L, Xiao X

OncoTargets and Therapy 2020, 13:7357-7368

Published Date: 28 July 2020

Retraction

Coronin3 Promotes Nasopharyngeal Carcinoma Migration and Invasion by Induction of Epithelial-to-Mesenchymal Transition [Retraction]

Fan L, Wei Y, Ding X, Li B

OncoTargets and Therapy 2020, 13:7355-7356

Published Date: 28 July 2020

Retraction

Extracellular Hsp90α Clinically Correlates with Tumor Malignancy and Promotes Migration and Invasion in Esophageal Squamous Cell Carcinoma [Retraction]

Wang X, An D, Wang X, Liu X, Li B

OncoTargets and Therapy 2020, 13:7353-7354

Published Date: 29 July 2020

Original Research

The KN Motif and Ankyrin Repeat Domains 1/CXXC Finger Protein 5 Axis Regulates Epithelial-Mesenchymal Transformation, Metastasis and Apoptosis of Gastric Cancer via Wnt Signaling

Chen X, Wang X, Yi L, Song Y

OncoTargets and Therapy 2020, 13:7343-7352

Published Date: 28 July 2020

Original Research

Traditional Chinese Medicine Xiaoai Jiedu Recipe Suppresses the Development of Hepatocellular Carcinoma via Regulating the microRNA-29a/Signal Transducer and Activator of Transcription 3 Axis

Shi Y, Kong W, Lu Y, Zheng Y

OncoTargets and Therapy 2020, 13:7329-7342

Published Date: 29 July 2020

Original Research

Methylcrotonoyl-CoA Carboxylase 2 Promotes Proliferation, Migration and Invasion and Inhibits Apoptosis of Prostate Cancer Cells Through Regulating GLUD1-P38 MAPK Signaling Pathway

He J, Mao Y, Huang W, Li M, Zhang H, Qing Y, Lu S, Xiao H, Li K

OncoTargets and Therapy 2020, 13:7317-7327

Published Date: 28 July 2020

Original Research

POLE Mutation Characteristics in a Chinese Cohort with Endometrial Carcinoma

Li Y, He Q, Li S, Wen X, Ye L, Wang K, Wan X

OncoTargets and Therapy 2020, 13:7305-7316

Published Date: 28 July 2020

Original Research

Analysis of Key Genes Regulating the Warburg Effect in Patients with Gastrointestinal Cancers and Selective Inhibition of This Metabolic Pathway in Liver Cancer Cells

Zhang X, Guo J, Jabbarzadeh Kaboli P, Zhao Q, Xiang S, Shen J, Zhao Y, Du F, Wu X, Li M, Ji H, Yang X, Xiao Z, Wen Q

OncoTargets and Therapy 2020, 13:7295-7304

Published Date: 27 July 2020

Original Research

The Combination of Plasma Fibrinogen Concentration and Neutrophil Lymphocyte Ratio (F-NLR) as a Prognostic Factor of Epithelial Ovarian Cancer

Yang J, Ma J, Cheng S, Wang Y

OncoTargets and Therapy 2020, 13:7283-7293

Published Date: 27 July 2020

Original Research

TBRG4 Knockdown Suppresses Proliferation and Growth of Human Osteosarcoma Cell Lines MG63 Through PI3K/Akt Pathway

Huang F, Liao F, Ma G, Hu Y, Zhang C, Xu P, Xu T, Chang J

OncoTargets and Therapy 2020, 13:7271-7281

Published Date: 27 July 2020

Original Research

Long Noncoding RNA ST7-AS1 Upregulates TRPM7 Expression by Sponging microRNA-543 to Promote Cervical Cancer Progression

Qi H, Lu L, Wang L

OncoTargets and Therapy 2020, 13:7257-7269

Published Date: 27 July 2020

Original Research

Low Expression of APOB mRNA or Its Hypermethylation Predicts Favorable Overall Survival in Patients with Low-Grade Glioma

Han C, He Y, Chen L, Wang J, Jiao S, Xia X, Li G, Yao S

OncoTargets and Therapy 2020, 13:7243-7255

Published Date: 27 July 2020

Review

Combination of Immune Checkpoint Inhibitors with Chemotherapy in Lung Cancer

Liu W, Zhang L, Xiu Z, Guo J, Wang L, Zhou Y, Jiao Y, Sun M, Cai J

OncoTargets and Therapy 2020, 13:7229-7241

Published Date: 27 July 2020

Original Research

miR-3609 Decelerates the Clearance of Sorafenib in Hepatocellular Carcinoma Cells by Targeting EPAS-1 and Reducing the Activation of the Pregnane X Receptor Pathway

Shao QP, Wei C, Yang J, Zhang WZ

OncoTargets and Therapy 2020, 13:7213-7227

Published Date: 27 July 2020

Original Research

Discovering Biomarkers in Peritoneal Metastasis of Gastric Cancer by Metabolomics

Pan G, Ma Y, Suo J, Li W, Zhang Y, Qin S, Jiao Y, Zhang S, Li S, Kong Y, Du Y, Gao S, Wang D

OncoTargets and Therapy 2020, 13:7199-7211

Published Date: 27 July 2020

Case Series

Effective Treatment with PD-1 Antibody, Chidamide, Etoposide, and Thalidomide (PCET) for Relapsed/Refractory Natural Killer/T-Cell Lymphoma: A Report of Three Cases

Du L, Zhang L, Li L, Li X, Yan J, Wang X, Fu X, Sun Z, Zhang X, Li Z, Wu J, Yu H, Chang Y, Zhou Z, Nan F, Wu X, Tian L, Zhang M

OncoTargets and Therapy 2020, 13:7189-7197

Published Date: 27 July 2020

Original Research

miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma

Zong S, Zhao J, Liu L

OncoTargets and Therapy 2020, 13:7177-7188

Published Date: 27 July 2020

Original Research

Novel mTOR Inhibitor Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Molecular Targeting Agents

Feng YQ, Li BA, Feng F, Chen YS, Ren YX, Zhang H, Cao S

OncoTargets and Therapy 2020, 13:7165-7176

Published Date: 27 July 2020

Original Research

Baicalin Attenuates YAP Activity to Suppress Ovarian Cancer Stemness

Li Y, Wang D, Liu J, Li Y, Chen D, Zhou L, Lang T, Zhou Q

OncoTargets and Therapy 2020, 13:7151-7163

Published Date: 24 July 2020

Original Research

LINC00501 Inhibits the Growth and Metastasis of Lung Cancer by Mediating miR-129-5p/HMGB1

Wang RT, Zhang Y, Yao SY, Tan XG

OncoTargets and Therapy 2020, 13:7137-7149

Published Date: 24 July 2020

Original Research

Upregulation of FTX Promotes Osteosarcoma Tumorigenesis by Increasing SOX4 Expression via miR-214-5p

Chen H, Liu T, Ouyang H, Lin S, Zhong H, Zhang H, Yang Y

OncoTargets and Therapy 2020, 13:7125-7136

Published Date: 23 July 2020

Original Research

Long Non-Coding RNA DUXAP8 Facilitates Cell Viability, Migration, and Glycolysis in Non-Small-Cell Lung Cancer via Regulating HK2 and LDHA by Inhibition of miR-409-3p

Yin D, Hua L, Wang J, Liu Y, Li X

OncoTargets and Therapy 2020, 13:7111-7123

Published Date: 22 July 2020

Original Research

Comparison of Next-Generation Sequencing and Ventana Immunohistochemistry in Detecting ALK Rearrangements and Predicting the Efficacy of First-Line Crizotinib in Patients with Advanced Non-Small Cell Lung Cancer

Zeng L, Li Y, Xu Q, Jiang W, Lizaso A, Mao X, Zhang Y, Yang N, Wang Z

OncoTargets and Therapy 2020, 13:7101-7109

Published Date: 22 July 2020

Original Research

Long Noncoding RNA ADAMTS9-AS2 Inhibits the Proliferation, Migration, and Invasion in Bladder Tumor Cells

Zhang Z, Jia JP, Zhang YJ, Liu G, Zhou F, Zhang BC

OncoTargets and Therapy 2020, 13:7089-7100

Published Date: 21 July 2020

Review

Long Non-Coding RNAs in Drug Resistance of Breast Cancer

Du T, Shi Y, Xu S, Wan X, Sun H, Liu B

OncoTargets and Therapy 2020, 13:7075-7087

Published Date: 21 July 2020

Original Research

Up-Regulation of Tiam1 Promotes the Radioresistance of Laryngeal Squamous Cell Carcinoma Through Activation of the JNK/ATF-2 Signaling Pathway

Wang S, Zhu W, Ouyang L, Li J, Li S, Yang X

OncoTargets and Therapy 2020, 13:7065-7074

Published Date: 21 July 2020

Original Research

Resveratrol Suppresses Tumor Progression via Inhibiting STAT3/HIF-1α/VEGF Pathway in an Orthotopic Rat Model of Non-Small-Cell Lung Cancer (NSCLC)

Wang H, Jia R, Lv T, Wang M, He S, Zhang X

OncoTargets and Therapy 2020, 13:7057-7063

Published Date: 21 July 2020

Original Research

LncRNA EMX2OS, Regulated by TCF12, Interacts with FUS to Regulate the Proliferation, Migration and Invasion of Prostate Cancer Cells Through the cGMP-PKG Signaling Pathway

Wang Z, Zhang C, Chang J, Tian X, Zhu C, Xu W

OncoTargets and Therapy 2020, 13:7045-7056

Published Date: 21 July 2020

Original Research

WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling

Dai J, Jiang L, Qiu L, Shao Y, Shi P, Li J

OncoTargets and Therapy 2020, 13:7033-7044

Published Date: 20 July 2020

Original Research

Long Non-Coding RNA TP73-AS1 Promotes the Development of Lung Cancer by Targeting the miR-27b-3p/LAPTM4B Axis

Jiang Q, Xing W, Cheng J, Yu Y

OncoTargets and Therapy 2020, 13:7019-7031

Published Date: 20 July 2020

Original Research

Disruption of LTBP4 Induced Activated TGFβ1, Immunosuppression Signal and Promoted Pulmonary Metastasis in Hepatocellular Carcinoma

Yang X, Ye X, Zhang L, Zhang X, Shu P

OncoTargets and Therapy 2020, 13:7007-7017

Published Date: 20 July 2020

Original Research

Combination of CpG Oligodeoxynucleotide and Anti-4-1BB Antibody in the Treatment of Multiple Hepatocellular Carcinoma in Mice

Ma S, Yang X, Zhou H, Zhang C, Kang J, Sun D

OncoTargets and Therapy 2020, 13:6997-7005

Published Date: 20 July 2020

Original Research

Effect of Malus asiatica Nakai Leaf Flavonoids on the Prevention of Esophageal Cancer in C57BL/6J Mice by Regulating the IL-17 Signaling Pathway

Jia XB, Zhang Q, Xu L, Yao WJ, Wei L

OncoTargets and Therapy 2020, 13:6987-6996

Published Date: 17 July 2020

Original Research

Co-Expression Network Analysis Identified LTF in Association with Metastasis Risk and Prognosis in Clear Cell Renal Cell Carcinoma

Ni L, Yuan C, Zhang C, Xiang Y, Wu J, Wang X, Wu X

OncoTargets and Therapy 2020, 13:6975-6986

Published Date: 17 July 2020

Original Research

Upregulation of TRIAP1 by the lncRNA MFI2-AS1/miR-125a-5p Axis Promotes Thyroid Cancer Tumorigenesis

Yu T, Tong L, Ao Y, Zhang G, Liu Y, Zhang H

OncoTargets and Therapy 2020, 13:6967-6974

Published Date: 17 July 2020

Original Research

Upregulation of MiR-1274a is Correlated with Survival Outcomes and Promotes Cell Proliferation, Migration, and Invasion of Colon Cancer

Ren B, Yang B, Li P, Ge L

OncoTargets and Therapy 2020, 13:6957-6966

Published Date: 17 July 2020

Review

Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma

Han W, Shi J, Cao J, Dong B, Guan W

OncoTargets and Therapy 2020, 13:6937-6955

Published Date: 16 July 2020

Original Research

Evaluating Solid Lung Adenocarcinoma Anaplastic Lymphoma Kinase Gene Rearrangement Using Noninvasive Radiomics Biomarkers

Ma DN, Gao XY, Dan YB, Zhang AN, Wang WJ, Yang G, Zhu HZ

OncoTargets and Therapy 2020, 13:6927-6935

Published Date: 16 July 2020

Original Research

Suppression of CXCL-1 Could Restore Necroptotic Pathway in Chronic Lymphocytic Leukemia

Xu Z, Sun Y, Wei Z, Jiang J, Xu J, Liu P

OncoTargets and Therapy 2020, 13:6917-6925

Published Date: 16 July 2020

Original Research

Anti-Cancer Activity of Acriflavine as Metabolic Inhibitor of OXPHOS in Pancreas Cancer Xenografts

Bulle A, Dekervel J, Deschuttere L, Nittner D, Van Cutsem E, Verslype C, van Pelt J

OncoTargets and Therapy 2020, 13:6907-6916

Published Date: 15 July 2020

Original Research

PIM3 Promotes the Proliferation and Migration of Acute Myeloid Leukemia Cells

Luo H, Sun R, Zheng Y, Huang J, Wang F, Long D, Wu Y

OncoTargets and Therapy 2020, 13:6897-6905

Published Date: 14 July 2020

Review

Update on Targeted Therapies for Advanced Non-Small Cell Lung Cancer: Durvalumab in Context

Gullapalli S, Remon J, Hendriks LEL, Lopes G

OncoTargets and Therapy 2020, 13:6885-6896

Published Date: 14 July 2020

Original Research

MicroRNA-27a-3p Reverses Adriamycin Resistance by Targeting BTG2 and Activating PI3K/Akt Pathway in Breast Cancer Cells

Zhu B, Chen W, Fu Y, Cui X, Jin L, Chao J, Yun X, Gao P, Shan S, Li J, Yin X, Zhu C, Qin X

OncoTargets and Therapy 2020, 13:6873-6884

Published Date: 14 July 2020

Review

HMGB1 in Radiotherapy: A Two Headed Signal Regulating Tumor Radiosensitivity and Immunity

Liao Y, Liu S, Fu S, Wu J

OncoTargets and Therapy 2020, 13:6859-6871

Published Date: 14 July 2020

Expression of Concern

PP4R1 Accelerates Cell Growth and Proliferation in HepG2 Hepatocellular Carcinoma [Expression of Concern]

Wu G, Ma Z, Qian J, Liu B

OncoTargets and Therapy 2020, 13:6857-6858

Published Date: 14 July 2020

Expression of Concern

miR-139-5p Regulates Proliferation, Apoptosis, and Cell Cycle of Uterine Leiomyoma Cells by Targeting TPD52 [Expression of Concern]

Chen H, Xu H, Meng YG, Zhang Y, Chen JY, Wei XN

OncoTargets and Therapy 2020, 13:6855-6856

Published Date: 14 July 2020

Retraction

Estrogen Receptor Beta Inhibits the Proliferation, Migration, and Angiogenesis of Gastric Cancer Cells Through Inhibiting Nuclear Factor-Kappa B Signaling [Retraction]

Zhang Y, Wu Y, Zhou X, Yi B, Wang L

OncoTargets and Therapy 2020, 13:6853-6854

Published Date: 14 July 2020

Retraction

MicroRNA-145 Inhibits the Activation of the mTOR Signaling Pathway to Suppress the Proliferation and Invasion of Invasive Pituitary Adenoma Cells by Targeting AKT3 in vivo and in vitro [Retraction]

Zhou K, Fan Y, Wu P, Duysenbi S, Feng Z, Du G, Zhang T

OncoTargets and Therapy 2020, 13:6851-6852

Published Date: 14 July 2020

Retraction

Overexpression of ERβ Participates in the Progression of Liver Cancer via Inhibiting the Notch Signaling Pathway [Retraction]

Zhang Y, Yi B, Zhou X, Wu Y, Wang L

OncoTargets and Therapy 2020, 13:6849-6850

Published Date: 16 July 2020

Retraction

miR-125a Restrains Cell Migration and Invasion by Targeting STAT3 in Gastric Cancer Cells [Retraction]

Yang L, Zhang S, Guo K, Huang H, Qi S, Yao J, Zhang Z

OncoTargets and Therapy 2020, 13:6847-6848

Published Date: 14 July 2020

Review

The Role of Methyltransferase NSD2 as a Potential Oncogene in Human Solid Tumors

Chen R, Chen Y, Zhao W, Fang C, Zhou W, Yang X, Ji M

OncoTargets and Therapy 2020, 13:6837-6846

Published Date: 13 July 2020

Original Research

LncRNA GA-Binding Protein Transcription Factor Subunit Beta-1 Antisense RNA 1 Inhibits Renal Carcinoma Growth Through an MiR-1246/Phosphoenolpyruvate Carboxykinase 1 Pathway

Gao S, Zhang F, Sun H, Yang X

OncoTargets and Therapy 2020, 13:6827-6836

Published Date: 12 July 2020

Case report

Giant Cell-Rich Solitary Fibrous Tumor in the Nasopharynx: Case Report and Literature Review

Dong SS, Wang N, Yang CP, Zhang GC, Liang WH, Zhao J, Qi Y

OncoTargets and Therapy 2020, 13:6819-6826

Published Date: 12 July 2020

Original Research

Identification of Important Modules and Biomarkers in Breast Cancer Based on WGCNA

Tian Z, He W, Tang J, Liao X, Yang Q, Wu Y, Wu G

OncoTargets and Therapy 2020, 13:6805-6817

Published Date: 12 July 2020

Original Research

MORC4 Promotes Chemoresistance of Luminal A/B Breast Cancer via STAT3-Mediated MID2 Upregulation

Luo J, Zeng S, Tian C

OncoTargets and Therapy 2020, 13:6795-6803

Published Date: 12 July 2020

Case Series

Radiofrequency Ablation with Continued EGFR Tyrosine Kinase Inhibitor Therapy Prolongs Disease Control in EGFR-Mutant Advanced Lung Cancers with Acquired Resistance to EGFR Tyrosine Kinase Inhibitors: Two Case Reports

Shi X, Zhou J, Qian C, Gao L, Wang B, Feng X

OncoTargets and Therapy 2020, 13:6789-6793

Published Date: 13 July 2020

Original Research

RNA-Seq Profiling of Circular RNAs and the Oncogenic Role of circPVT1 in Cutaneous Squamous Cell Carcinoma

Chen S, Ding J, Wang Y, Lu T, Wang L, Gao X, Chen H, Qu L, He C

OncoTargets and Therapy 2020, 13:6777-6788

Published Date: 12 July 2020

Original Research

miR-602 Mediates the RASSF1A/JNK Pathway, Thereby Promoting Postoperative Recurrence in Nude Mice with Liver Cancer

Zhou C, Huang Y, Chen Y, Xie Y, Wen H, Tan W, Wang C

OncoTargets and Therapy 2020, 13:6767-6776

Published Date: 10 July 2020

Original Research

Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs

Sun F, Wu K, Yao Z, Mu X, Zheng Z, Sun M, Wang Y, Liu Z, Zhu Y

OncoTargets and Therapy 2020, 13:6755-6765

Published Date: 10 July 2020

Case report

Primary Resistance to Combination Therapy with First- and Third-Generation EGFR Tyrosine Kinase Inhibitors of Lung Adenocarcinoma Harboring EGFR 19Del/T790M/in Trans-C797S Mutations with Co-Occurring CTNNB1 Alteration

Chen J, Wang J, Wu X

OncoTargets and Therapy 2020, 13:6749-6753

Published Date: 9 July 2020

Expression of Concern

Long Noncoding RNA SNHG15 Serves as an Oncogene and Predicts Poor Prognosis in Epithelial Ovarian Cancer [Expression of Concern]

Qu C, Dai C, Guo Y, Qin R, Liu J

OncoTargets and Therapy 2020, 13:6747-6748

Published Date: 9 July 2020

Original Research

GINS2 Functions as a Key Gene in Lung Adenocarcinoma by WGCNA Co-Expression Network Analysis

Tian W, Yang X, Yang H, Zhou B

OncoTargets and Therapy 2020, 13:6735-6746

Published Date: 8 July 2020

Original Research

A Four Gene-Based Risk Score System Associated with Chemoradiotherapy Response and Tumor Recurrence in Rectal Cancer by Co-Expression Network Analysis

Sun Y, Zhang Y, Wu X, Chi P

OncoTargets and Therapy 2020, 13:6721-6733

Published Date: 8 July 2020

Original Research

Exosomal miR-638 Inhibits Hepatocellular Carcinoma Progression by Targeting SP1

Yang J, Li B, Zhao S, Du H, Du Y

OncoTargets and Therapy 2020, 13:6709-6720

Published Date: 7 July 2020

Original Research

Ribosome Binding Protein 1 Correlates with Prognosis and Cell Proliferation in Bladder Cancer

Lv S, Shi Z, Wang X, Zheng P, Li H, Han Q, Li Z

OncoTargets and Therapy 2020, 13:6699-6707

Published Date: 7 July 2020

Original Research

miR-188-5p Promotes Tumor Growth by Targeting CD2AP Through PI3K/AKT/mTOR Signaling in Children with Acute Promyelocytic Leukemia

Wang D, Chen J, Ding Y, Kong H, You H, Zhao Y, Wei H, Liu Y

OncoTargets and Therapy 2020, 13:6681-6697

Published Date: 7 July 2020

Case report

Coexistence of Low-Grade Fetal Adenocarcinoma and Adenocarcinoma in situ of the Lung Harboring Different Genetic Mutations: A Case Report and Review of Literature

Liu S, Wang J, Luo X, Li X, Miao Y, Wang L, Li Q, Qiu X, Wang EH

OncoTargets and Therapy 2020, 13:6675-6680

Published Date: 7 July 2020

Original Research

Coronin 3 Promotes the Development of Oncogenic Properties in Glioma Through the Wnt/β-Catenin Signaling Pathway

Wang M, Li Q, Yu S, Zhang Z, Qiu P, Zhang Y, Yang W, Xu G, Xu T

OncoTargets and Therapy 2020, 13:6661-6673

Published Date: 7 July 2020

Original Research

Pristimerin Suppressed Breast Cancer Progression via miR-542-5p/DUB3 Axis

Cheng S, Zhang Z, Hu C, Xing N, Xia Y, Pang B

OncoTargets and Therapy 2020, 13:6651-6660

Published Date: 7 July 2020

Case Series

Association of TP53 Mutations with Response to Anlotinib Treatment in Advanced Non-Small Cell Lung Cancer

Fang S, Cheng W, Zhang M, Yang R

OncoTargets and Therapy 2020, 13:6645-6650

Published Date: 7 July 2020

Original Research

ARPP-19 Mediates Herceptin Resistance via Regulation of CD44 in Gastric Cancer

Gao X, Lu C, Chen C, Sun K, Liang Q, Shuai J, Wang X, Xu Y

OncoTargets and Therapy 2020, 13:6629-6643

Published Date: 7 July 2020

Original Research

Rat Bone Marrow-Derived Mesenchymal Stem Cells Promote the Migration and Invasion of Colorectal Cancer Stem Cells

Zou W, Zhao J, Li Y, Wang Z, Yan H, Liu Y, Sun M, Zhuang J, Wang J

OncoTargets and Therapy 2020, 13:6617-6628

Published Date: 7 July 2020

Review

MicroRNA-154: A Novel Candidate for Diagnosis and Therapy of Human Cancers

Nazarizadeh A, Mohammadi F, Alian F, Faraji P, Nourbakhsh M, Alizadeh-Fanalou S

OncoTargets and Therapy 2020, 13:6603-6615

Published Date: 7 July 2020

Original Research

Clinical Significance of ZNF711 in Human Breast Cancer

Li X, Tian L, Zhang L, Xu B, Zhang Y, Li Q

OncoTargets and Therapy 2020, 13:6593-6601

Published Date: 6 July 2020

Original Research

The CXCR4 Antagonist, AMD3100, Reverses Mesenchymal Stem Cell-Mediated Drug Resistance in Relapsed/Refractory Acute Lymphoblastic Leukemia

Wang S, Wang X, Liu S, Zhang S, Wei X, Song Y, Yin Q

OncoTargets and Therapy 2020, 13:6583-6591

Published Date: 6 July 2020

Review

Evaluating the Therapeutic Potential of Zanubrutinib in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma: Evidence to Date

Sawalha Y, Bond DA, Alinari L

OncoTargets and Therapy 2020, 13:6573-6581

Published Date: 6 July 2020

Original Research

Interactive Effects of PD-L1 Expression in Tumor and Immune Cells on Prognosis of Esophageal Squamous Cell Carcinoma: A One-Center Retrospective Cohort Study

Shi F, Xiao S, Miller KB, Zhao Y, Li Y, Gao Y, Chang H, Song Q, Qu C

OncoTargets and Therapy 2020, 13:6565-6572

Published Date: 3 July 2020

Original Research

LncRNA HCG11 Suppresses Cell Proliferation and Promotes Apoptosis via Sponging miR-224-3p in Non-Small-Cell Lung Cancer Cells

Wang G, Liu L, Zhang J, Huang C, Chen Y, Bai W, Wang Y, Zhao K, Li S

OncoTargets and Therapy 2020, 13:6553-6563

Published Date: 3 July 2020

Original Research

lncRNA TMPO-AS1 Exerts Oncogenic Roles in HCC Through Regulating miR-320a/SERBP1 Axis

Wang Z, Huang D, Huang J, Nie K, Li X, Yang X

OncoTargets and Therapy 2020, 13:6539-6551

Published Date: 3 July 2020

Original Research

Downregulation of RRM2 Attenuates Retroperitoneal Liposarcoma Progression via the Akt/mTOR/4EBP1 Pathway: Clinical, Biological, and Therapeutic Significance

Zhang S, Yan L, Cui C, Wang Z, Wu J, Lv A, Zhao M, Dong B, Zhang W, Guan X, Tian X, Hao C

OncoTargets and Therapy 2020, 13:6523-6537

Published Date: 3 July 2020

Original Research

LINC00665 Promotes the Progression of Multiple Myeloma by Adsorbing miR-214-3p and Positively Regulating the Expression of PSMD10 and ASF1B

Wang C, Li M, Wang S, Jiang Z, Liu Y

OncoTargets and Therapy 2020, 13:6511-6522

Published Date: 7 July 2020

Original Research

A Six-Epithelial–Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer

Wei LY, Zhang XJ, Wang L, Hu LN, Zhang XD, Li L, Gao JN

OncoTargets and Therapy 2020, 13:6497-6509

Published Date: 3 July 2020

Original Research

Sequential Whole Exome Sequencing Reveals Somatic Mutations Associated with Platinum Response in NSCLC

Guo AX, Xiao F, Shao WH, Zhan Y, Zhang L, Xiong J, Gao Y, Yin JY

OncoTargets and Therapy 2020, 13:6485-6496

Published Date: 3 July 2020

Original Research

Expression of PD-1 and PD-L1 on Tumor-Infiltrating Lymphocytes Predicts Prognosis in Patients with Small-Cell Lung Cancer

Sun C, Zhang L, Zhang W, Liu Y, Chen B, Zhao S, Li W, Wang L, Ye L, Jia K, Wang H, Wu C, He Y, Zhou C

OncoTargets and Therapy 2020, 13:6475-6483

Published Date: 3 July 2020

Original Research

miR-195 Serves as a Tumor Suppressor in the Progression of Liposarcoma by Targeting OSBP

Cao Y, Li L, Han L, Zheng J, Lv C

OncoTargets and Therapy 2020, 13:6465-6474

Published Date: 6 July 2020

Original Research

Overexpression of LRRC59 Is Associated with Poor Prognosis and Promotes Cell Proliferation and Invasion in Lung Adenocarcinoma

Li D, Xing Y, Tian T, Guo Y, Qian J

OncoTargets and Therapy 2020, 13:6453-6463

Published Date: 3 July 2020

Original Research

S100A9 promotes prostate cancer cell invasion by activating TLR4/NF-κB/integrin β1/FAK signaling

Lv Z, Li W, Wei X

OncoTargets and Therapy 2020, 13:6443-6452

Published Date: 3 July 2020

Original Research

Chloroquine Combined with Imatinib Overcomes Imatinib Resistance in Gastrointestinal Stromal Tumors by Inhibiting Autophagy via the MAPK/ERK Pathway

Zheng S, Shu Y, Lu Y, Sun Y

OncoTargets and Therapy 2020, 13:6433-6441

Published Date: 2 July 2020

Case report

Invasive Micropapillary Carcinoma with CEP17 Monosomy of the Bilateral Breast: A Rare Case Report and Review of the Literature

Zhang L, Wang Y, Zhang L, Xing H, Niu C, Yu Q, Tang L

OncoTargets and Therapy 2020, 13:6425-6432

Published Date: 2 July 2020

Short Report

Adipose-Derived Stem Cells Can Replace Fibroblasts as Cell Control for Anti-Tumor Screening Assay

Pham PV, Nguyen ST, Phan NLC, Do NM, Vo PH

OncoTargets and Therapy 2020, 13:6417-6423

Published Date: 2 July 2020

Review

Clinical Utility of Selinexor/Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma: A Review of Current Evidence and Patient Selection

Malandrakis P, Ntanasis-Stathopoulos I, Gavriatopoulou M, Terpos E

OncoTargets and Therapy 2020, 13:6405-6416

Published Date: 1 July 2020

Review

Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers

Han W, Shi J, Cao J, Dong B, Guan W

OncoTargets and Therapy 2020, 13:6393-6403

Published Date: 1 July 2020

Case report

Olaparib and Pembrolizumab Treatment for BRCA1-Mutated and PD-L1-Positive Intrahepatic Cholangiocarcinoma Recurrence and Metastasis: A Case Report

Xiong F, Gong J, Wang Q

OncoTargets and Therapy 2020, 13:6385-6391

Published Date: 1 July 2020

Original Research

LncRNA NEAT1 Regulates 5-Fu Sensitivity, Apoptosis and Invasion in Colorectal Cancer Through the MiR-150-5p/CPSF4 Axis

Wang X, Jiang G, Ren W, Wang B, Yang C, Li M

OncoTargets and Therapy 2020, 13:6373-6383

Published Date: 1 July 2020

Original Research

LncRNA TTN-AS1 Promotes Progression of Non-Small Cell Lung Cancer via Regulating miR-491-5p/ZNF503 Axis

Qi G, Li L

OncoTargets and Therapy 2020, 13:6361-6371

Published Date: 1 July 2020

Review

A Review of MicroRNA in Uveal Melanoma

Li YF, Dong L, Li Y, Wei WB

OncoTargets and Therapy 2020, 13:6351-6359

Published Date: 1 July 2020

Original Research

Helicobacter pylori CagA Protein Attenuates 5-Fu Sensitivity of Gastric Cancer Cells Through Upregulating Cellular Glucose Metabolism

Gao S, Song D, Liu Y, Yan H, Chen X

OncoTargets and Therapy 2020, 13:6339-6349

Published Date: 1 July 2020

Original Research

circPDSS1 Stimulates the Development of Colorectal Cancer via Activating the Wnt/β-Catenin Signaling

Fang Q, Yang A, Dong A, Zhao L

OncoTargets and Therapy 2020, 13:6329-6337

Published Date: 30 June 2020

Original Research

Hsa_circ_0001806 Acts as a ceRNA to Facilitate the Stemness of Colorectal Cancer Cells by Increasing COL1A1

Sun J, Liu J, Zhu Q, Xu F, Kang L, Shi X

OncoTargets and Therapy 2020, 13:6315-6327

Published Date: 30 June 2020

Original Research

GRHL2 Upregulation Predicts a Poor Prognosis and Promotes the Resistance of Serous Ovarian Cancer to Cisplatin

Nie Y, Ding Y, Yang M

OncoTargets and Therapy 2020, 13:6303-6314

Published Date: 30 June 2020

Original Research

LncRNA SLC7A11-AS1 Contributes to Lung Cancer Progression Through Facilitating TRAIP Expression by Inhibiting miR-4775

Liu Y, Fan X, Zhao Z, Shan X

OncoTargets and Therapy 2020, 13:6295-6302

Published Date: 30 June 2020

Case report

Response to Pyrotinib in a Chinese Patient with Bone-Metastatic Scrotal Paget’s Disease Harboring Triple Uncommon HER2 Mutation: A Case Report

Guo JJ, Jiao XD, Wu Y, Qin BD, Liu K, Zang YS

OncoTargets and Therapy 2020, 13:6289-6293

Published Date: 30 June 2020

Original Research

Down-Regulation of circNRIP1 Promotes the Apoptosis and Inhibits the Migration and Invasion of Gastric Cancer Cells by miR-182/ROCK1 Axis

Liang L, Li L

OncoTargets and Therapy 2020, 13:6279-6288

Published Date: 30 June 2020

Original Research

GOLPH3 Promotes Angiogenesis of Lung Adenocarcinoma by Regulating the Wnt/β-Catenin Signaling Pathway

Zhao C, Zhang J, Ma L, Wu H, Zhang H, Su J, Geng B, Yao Q, Zheng J

OncoTargets and Therapy 2020, 13:6265-6277

Published Date: 30 June 2020

Original Research

miR-335-5p Regulates Cell Cycle and Metastasis in Lung Adenocarcinoma by Targeting CCNB2

Wang X, Xiao H, Wu D, Zhang D, Zhang Z

OncoTargets and Therapy 2020, 13:6255-6263

Published Date: 30 June 2020

Original Research

Incidence and PD-L1 Expression of MET 14 Skipping in Chinese Population: A Non-Selective NSCLC Cohort Study Using RNA-Based Sequencing

Xu Z, Li H, Dong Y, Cheng P, Luo F, Fu S, Gao M, Kong L, Che N

OncoTargets and Therapy 2020, 13:6245-6253

Published Date: 30 June 2020

Original Research

CCDC7 Activates Interleukin-6 and Vascular Endothelial Growth Factor to Promote Proliferation via the JAK-STAT3 Pathway in Cervical Cancer Cells

Zhou C, He X, Zeng Q, Zhang P, Wang C

OncoTargets and Therapy 2020, 13:6229-6244

Published Date: 30 June 2020

Review

Autophagy-Related Beclin 1 and Head and Neck Cancers

Hu YJ, Zhong JT, Gong L, Zhang SC, Zhou SH

OncoTargets and Therapy 2020, 13:6213-6227

Published Date: 30 June 2020

Original Research

Long Noncoding RNA CAR10 Contributes to Melanoma Progression By Suppressing miR-125b-5p to Induce RAB3D Expression

Xie J, Zheng Y, Xu X, Sun C, Lv M

OncoTargets and Therapy 2020, 13:6203-6211

Published Date: 29 June 2020

Original Research

UBE2O Promotes Progression and Epithelial–Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma

Chen X, Zhang S, Liu C, Li G, Lu S, Wang Y, Zhang X, Huang D, Qiu Y, Liu Y

OncoTargets and Therapy 2020, 13:6191-6202

Published Date: 29 June 2020

Original Research

LINC00565 Enhances Proliferative Ability in Endometrial Carcinoma by Downregulating KLF9

Yin X, Li X, Feng G, Qu Y, Wang H

OncoTargets and Therapy 2020, 13:6181-6189

Published Date: 29 June 2020

Original Research

A Novel Circular RNA, circ_0005394, Predicts Unfavorable Prognosis and Contributes to Hepatocellular Carcinoma Progression by Regulating miR-507/E2F3 and miR-515-5p/CXCL6 Signaling Pathways

Sun C, Li G, Liu M

OncoTargets and Therapy 2020, 13:6171-6180

Published Date: 29 June 2020

Original Research

Circular RNA 0001073 Attenuates Malignant Biological Behaviours in Breast Cancer Cell and Is Delivered by Nanoparticles to Inhibit Mice Tumour Growth

Yi Z, Li Y, Wu Y, Zeng B, Li H, Ren G, Wang X

OncoTargets and Therapy 2020, 13:6157-6169

Published Date: 29 June 2020

Original Research

Genes Regulated by HPV 16 E6 and High Expression of NFX1-123 in Cervical Cancers

Chintala S, Levan J, Robinson K, Quist K, Katzenellenbogen RA

OncoTargets and Therapy 2020, 13:6143-6156

Published Date: 26 June 2020

Original Research

RPL38 Regulates the Proliferation and Apoptosis of Gastric Cancer via miR-374b-5p/VEGF Signal Pathway

Ji H, Zhang X

OncoTargets and Therapy 2020, 13:6131-6141

Published Date: 26 June 2020

Review

Immunotherapy For Ovarian Cancer: Recent Advances And Combination Therapeutic Approaches

Palaia I, Tomao F, Sassu CM, Musacchio L, Benedetti Panici P

OncoTargets and Therapy 2020, 13:6109-6129

Published Date: 26 June 2020

Original Research

Differential Metabolic Alterations and Biomarkers Between Gastric Cancer and Colorectal Cancer: A Systematic Review and Meta-Analysis

Tian J, Xue W, Yin H, Zhang N, Zhou J, Long Z, Wu C, Liang Z, Xie K, Li S, Li L, Wu Z, Daria V, Zhao Y, Wang F, Wang M

OncoTargets and Therapy 2020, 13:6093-6108

Published Date: 25 June 2020

Case report

Isolated Intracranial Myeloid Sarcoma Mimicking Malignant Lymphoma: A Diagnostic Challenge and Literature Reviews

Xu G, Zhang H, Nong W, Li C, Meng L, Liu C, Li F

OncoTargets and Therapy 2020, 13:6085-6092

Published Date: 25 June 2020

Original Research

Hypoxia-Induced Placenta-Specific microRNA (miR-512-3p) Promotes Hepatocellular Carcinoma Progression by Targeting Large Tumor Suppressor Kinase 2

Zhang B, Huang L, Tu J, Wu T

OncoTargets and Therapy 2020, 13:6073-6083

Published Date: 25 June 2020

Original Research

LOXL1-AS1 Contributes to Non-Small Cell Lung Cancer Progression by Regulating miR-3128/RHOXF2 Axis

Zhao L, Zhang X, Guo H, Liu M, Wang L

OncoTargets and Therapy 2020, 13:6063-6071

Published Date: 25 June 2020

Original Research

CircHIPK3 Promotes Clear Cell Renal Cell Carcinoma (ccRCC) Cells Proliferation and Metastasis via Altering of miR-508-3p/CXCL13 Signal

Han B, Shaolong E, Luan L, Li N, Liu X

OncoTargets and Therapy 2020, 13:6051-6062

Published Date: 25 June 2020

Review

Targeting IFN/STAT1 Pathway as a Promising Strategy to Overcome Radioresistance

Liu S, Imani S, Deng Y, Pathak JL, Wen Q, Chen Y, Wu J

OncoTargets and Therapy 2020, 13:6037-6050

Published Date: 24 June 2020

Original Research

Upregulated lncRNA CASC9 Contributes to Progression of Non-Small Cell Lung Cancer Through Inhibition of miR-335-3p and Activation S100A14 Expression

Zhao W, Chen T, Zhao Y

OncoTargets and Therapy 2020, 13:6027-6036

Published Date: 24 June 2020

Original Research

The Anti-Tumor Effect of Nab-Paclitaxel Proven by Patient-Derived Organoids

Xiao X, Chen W, Wei ZW, Chu WW, Lu XF, Li B, Chen H, Meng SJ, Hao TF, Wei JT, He YL, Zhang CH

OncoTargets and Therapy 2020, 13:6017-6025

Published Date: 24 June 2020

Case report

Primary Urothelium Carcinoma of the Distal Urethra in a Male: Case Report and Literature Review

Wang N, Min J, Wei Q, Tan W, Dang Q

OncoTargets and Therapy 2020, 13:6011-6015

Published Date: 24 June 2020

Review

Safety and Efficacy of Brentuximab Vedotin in the Treatment of Classic Hodgkin Lymphoma

Makita S, Maruyama D, Tobinai K

OncoTargets and Therapy 2020, 13:5993-6009

Published Date: 23 June 2020

Original Research

SSPH I, a Novel Anti-Cancer Saponin, Inhibits Autophagy and Induces Apoptosis via ROS Accumulation and ERK1/2 Signaling Pathway in Hepatocellular Carcinoma Cells

Zhou J, Huang X, Qiu H, Gan R, Zhou H, Zhu H, Zhang X, Lu G, Liang G

OncoTargets and Therapy 2020, 13:5979-5991

Published Date: 23 June 2020

Original Research

AMPK α1 Downregulates ROS Levels Through Regulating Trx Leading to Dysfunction of Apoptosis in Non-Small Cell Lung Cancer

Gong D, Li Y, Wang Y, Chi B, Zhang J, Gu J, Yang J, Xu X, Hu S, Min L

OncoTargets and Therapy 2020, 13:5967-5977

Published Date: 23 June 2020

Original Research

HOPX Is an Epigenetically Inactivated Tumor Suppressor and Overexpression of HOPX Induce Apoptosis and Cell Cycle Arrest in Breast Cancer

You Q, Geng Y, Ye H, Zhu G, Gao X, Zhu H

OncoTargets and Therapy 2020, 13:5955-5965

Published Date: 23 June 2020

Original Research

Circ-PRKDC Contributes to 5-Fluorouracil Resistance of Colorectal Cancer Cells by Regulating miR-375/FOXM1 Axis and Wnt/β-Catenin Pathway

Chen H, Pei L, Xie P, Guo G

OncoTargets and Therapy 2020, 13:5939-5953

Published Date: 23 June 2020

Original Research

Quantitative Proteomics Analysis Indicates That Upregulation of lncRNA HULC Promotes Pathogenesis of Glioblastoma Cells

Hu Y, Ye S, Li Q, Yin T, Wu J, He J

OncoTargets and Therapy 2020, 13:5927-5938

Published Date: 22 June 2020

Original Research

Lnc HAGLR Promotes Colon Cancer Progression Through Sponging miR‐185‐5p and Activating CDK4 and CDK6 in vitro and in vivo

Sun W, Nie W, Wang Z, Zhang H, Li Y, Fang X

OncoTargets and Therapy 2020, 13:5913-5925

Published Date: 22 June 2020

Original Research

Implications of the Receptor Tyrosine Kinase Axl in Gastric Cancer Progression

He L, Lei Y, Hou J, Wu J, Lv G

OncoTargets and Therapy 2020, 13:5901-5911

Published Date: 22 June 2020

Review

Predictors of Neoadjuvant Chemotherapy Response in Breast Cancer: A Review

Xu W, Chen X, Deng F, Zhang J, Zhang W, Tang J

OncoTargets and Therapy 2020, 13:5887-5899

Published Date: 22 June 2020

Original Research

Autologous Cytokine-Induced Killer Cell Immunotherapy for Patients with High-Risk Diffuse Large B Cell Lymphoma After the First Complete Remission

Zhou M, Wang J, Li CP, Xu JY, Chen B

OncoTargets and Therapy 2020, 13:5879-5885

Published Date: 22 June 2020

Original Research

Effect of CXCR5-Positive Cell Infiltration on the Immune Contexture and Patient Prognosis in Head and Neck Squamous Cell Carcinoma

Chen J, Meng X, Zhou Q, Feng J, Zheng W, Wang Z, Wang J, Wang Y

OncoTargets and Therapy 2020, 13:5869-5877

Published Date: 22 June 2020

Original Research

Long Non-Coding RNA TUG1 Promotes Cell Proliferation and Inhibits Cell Apoptosis, Autophagy in Clear Cell Renal Cell Carcinoma via MiR-31-5p/FLOT1 Axis

Lv D, Xiang Y, Yang Q, Yao J, Dong Q

OncoTargets and Therapy 2020, 13:5857-5868

Published Date: 19 June 2020

Original Research

TDO Promotes Hepatocellular Carcinoma Progression

Li S, Li L, Wu J, Song F, Qin Z, Hou L, Xiao C, Weng J, Qin X, Xu J

OncoTargets and Therapy 2020, 13:5845-5855

Published Date: 19 June 2020

Case report

Primary Pulmonary Diffuse Large B Cell Lymphoma Mimicking Metastasis: A Case Report and Literature Review

Liu B, Liu H, Guo L, Ma Y, Guan M, Liu M

OncoTargets and Therapy 2020, 13:5837-5843

Published Date: 19 June 2020

Case report

A Serosa-Originated Gastric Stromal Tumor Misdiagnosed by Ultrasonography and Frozen Section Pathology: A Case Report

Ren L, Qian H, Wang J, Jin P, Hu Q, Yu J, Zhang X, Zhang Y, Huang H

OncoTargets and Therapy 2020, 13:5831-5835

Published Date: 19 June 2020

Original Research

TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling

Zhang X, Luo Y, Li Q

OncoTargets and Therapy 2020, 13:5819-5830

Published Date: 19 June 2020

Review

Long Non-Coding RNA MALAT1 as a Detection and Diagnostic Molecular Marker in Various Human Cancers: A Pooled Analysis Based on 3255 Subjects

Zhao Y, Yu Y, You S, Zhang C, Wu L, Zhao W, Wang X

OncoTargets and Therapy 2020, 13:5807-5817

Published Date: 19 June 2020

Original Research

B7-H6 Promotes Cell Proliferation, Migration and Invasion of Non-Hodgkin Lymphoma via Ras/MEK/ERK Pathway Based on Quantitative Phosphoproteomics Data

Yang S, Yuan L, Wang Y, Zhu M, Wang J, Ke X

OncoTargets and Therapy 2020, 13:5795-5805

Published Date: 18 June 2020

Review

The Biological Role of the Collagen Alpha-3 (VI) Chain and Its Cleaved C5 Domain Fragment Endotrophin in Cancer

Wang J, Pan W

OncoTargets and Therapy 2020, 13:5779-5793

Published Date: 22 June 2020

Original Research

Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells – Role of Snail, Slug and Twist and Small Molecule Inhibitors

Kaşıkcı E, Aydemir E, Bayrak ÖF, Şahin F

OncoTargets and Therapy 2020, 13:5763-5777

Published Date: 18 June 2020

Original Research

The Expression of IgG and IgG4 in Orbital MALT Lymphoma: The Similarities and Differences of IgG4-Related Diseases

Li KM, Xu MH, Wu X, He WM

OncoTargets and Therapy 2020, 13:5755-5761

Published Date: 17 June 2020

Original Research

CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway

Bai Y, Yin K, Su T, Ji F, Zhang S

OncoTargets and Therapy 2020, 13:5743-5753

Published Date: 17 June 2020

Original Research

Down-Regulated CMTM2 Promotes Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma

Zhang S, Tian R, Bei C, Zhang H, Kong J, Zheng C, Song X, Li D, Tan H, Zhu X, Tan S

OncoTargets and Therapy 2020, 13:5731-5741

Published Date: 17 June 2020

Original Research

Quiescin Sulfhydryl Oxidase 1 Regulates the Proliferation, Migration and Invasion of Human Glioblastoma Cells via PI3K/Akt Pathway

Geng Y, Xu C, Wang Y, Zhang L

OncoTargets and Therapy 2020, 13:5721-5729

Published Date: 17 June 2020

Original Research

Diagnostic Role of Dysregulated Circular RNA hsa_circ_0036722 in Laryngeal Squamous Cell Carcinoma

Guo Y, Huang Q, Zheng J, Hsueh CY, Yuan X, Heng Y, Zhou L

OncoTargets and Therapy 2020, 13:5709-5719

Published Date: 17 June 2020

Corrigendum

Minicircle DNA-Mediated CAR T Cells Targeting CD44 Suppressed Hepatocellular Carcinoma Both in vitro and in vivo [Corrigendum]

Wang H, Ye X, Ju Y, Cai Z, Wang X, Du P, Zhang M, Li Y, Cai J

OncoTargets and Therapy 2020, 13:5707-5708

Published Date: 17 June 2020

Review

Targeting the MET-Signaling Pathway in Non-Small–Cell Lung Cancer: Evidence to Date

Bylicki O, Paleiron N, Assié JB, Chouaïd C

OncoTargets and Therapy 2020, 13:5691-5706

Published Date: 17 June 2020

Review

Von Hippel-Lindau Disease: Current Challenges and Future Prospects

Gläsker S, Vergauwen E, Koch CA, Kutikov A, Vortmeyer AO

OncoTargets and Therapy 2020, 13:5669-5690

Published Date: 16 June 2020

Original Research

KIAA1522 Promotes the Progression of Hepatocellular Carcinoma via the Activation of the Wnt/β-Catenin Signaling Pathway

Jiang S, Zhang Y, Li Q, Qiu L, Bian B

OncoTargets and Therapy 2020, 13:5657-5668

Published Date: 16 June 2020

Original Research

LINC01224 Exhibits Cancer-Promoting Activity in Epithelial Ovarian Cancer Through microRNA-485-5p-Mediated PAK4 Upregulation

Xing S, Zhang Y, Zhang J

OncoTargets and Therapy 2020, 13:5643-5655

Published Date: 16 June 2020

Original Research

YAP1 Promotes Tumor Invasion and Metastasis in Nasopharyngeal Carcinoma with Hepatitis B Virus Infection

Huang Z, Su B, Liu F, Zhang N, Ye Y, Zhang Y, Zhen Z, Liang S, Liang S, Chen L, Luo W, Claret FX, Huang Y, Xu T

OncoTargets and Therapy 2020, 13:5629-5642

Published Date: 17 June 2020

Original Research

A Comprehensive Risk Assessment Model for Ovarian Cancer Patients with Phospho-STAT3 and IL-31 as Immune Infiltration Relevant Genes

Wang X, Lin F, Li J, Wang H

OncoTargets and Therapy 2020, 13:5617-5628

Published Date: 16 June 2020

Original Research

Eicosapentaenoic acid’s metabolism of 15-LOX-1 promotes the expression of miR-101 thus inhibits Cox2 pathway in colon cancer

Cai Y, Liu J, Cai S, Miao E, Jia C, Fan Y, Li Y

OncoTargets and Therapy 2020, 13:5605-5616

Published Date: 15 June 2020

Original Research

Inhibition of ERKs/Akt-Mediated c-Fos Expression Is Required for Piperlongumine-Induced Cyclin D1 Downregulation and Tumor Suppression in Colorectal Cancer Cells

Gao F, Zhou L, Li M, Liu W, Yang S, Li W

OncoTargets and Therapy 2020, 13:5591-5603

Published Date: 15 June 2020

Corrigendum

miR-140-3p Suppresses Cell Growth and Induces Apoptosis in Colorectal Cancer by Targeting PD-L1 [Corrigendum]

Jiang W, Li T, Wang J, Jiao R, Shi X, Huang X, Ji G

OncoTargets and Therapy 2020, 13:5589-5590

Published Date: 15 June 2020

Original Research

HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice

Afaloniati H, Angelopoulou K, Giakoustidis A, Hardas A, Pseftogas A, Makedou K, Gargavanis A, Goulopoulos T, Iliadis S, Papadopoulos V, Papalois A, Mosialos G, Poutahidis T, Giakoustidis D

OncoTargets and Therapy 2020, 13:5575-5588

Published Date: 15 June 2020

Original Research

Long Noncoding RNA SNHG12 Indicates the Prognosis and Accelerates Tumorigenesis of Diffuse Large B-Cell Lymphoma Through Sponging microR-195

Chen LY, Zhang XM, Han BQ, Dai HB

OncoTargets and Therapy 2020, 13:5563-5574

Published Date: 12 June 2020

Original Research

LINC00461 Overexpression Can Induce Docetaxel Resistance in Breast Cancer by Interacting with miR-411-5p

Zhang C, Wang J, Zhang J, Qu H, Tang X

OncoTargets and Therapy 2020, 13:5551-5562

Published Date: 12 June 2020

Original Research

Identification of Potential Key Genes and Pathways for Inflammatory Breast Cancer Based on GEO and TCGA Databases

Lv Q, Liu Y, Huang H, Zhu M, Wu J, Meng D

OncoTargets and Therapy 2020, 13:5541-5550

Published Date: 12 June 2020

Original Research

Hsa_circRNA_000166 Promotes Cell Proliferation, Migration and Invasion by Regulating miR-330-5p/ELK1 in Colon Cancer

Zhao G, Dai GJ

OncoTargets and Therapy 2020, 13:5529-5539

Published Date: 12 June 2020

Original Research

Highly Efficient Targeting of EGFR-Expressing Tumor Cells with UniCAR T Cells via Target Modules Based on Cetuximab®

Jureczek J, Feldmann A, Bergmann R, Arndt C, Berndt N, Koristka S, Loureiro LR, Mitwasi N, Hoffmann A, Kegler A, Bartsch T, Bachmann M

OncoTargets and Therapy 2020, 13:5515-5527

Published Date: 12 June 2020

Original Research

MicroRNA-92a Targets SERTAD3 and Regulates the Growth, Invasion, and Migration of Prostate Cancer Cells via the P53 Pathway

Zhang S, Yu J, Sun B, Hou G, Yu ZJ, Luo H

OncoTargets and Therapy 2020, 13:5495-5514

Published Date: 12 June 2020

Corrigendum

Long Noncoding RNA H19 Facilitates Small Cell Lung Cancer Tumorigenesis Through miR-140-5p/FGF9 Axis [Corrigendum]

Li X, Lv F, Li F, Du M, Liang Y, Ju S, Liu Z, Wang B, Gao Y

OncoTargets and Therapy 2020, 13:5493-5494

Published Date: 12 June 2020

Original Research

Knockdown of TRIM37 Promotes Apoptosis and Suppresses Tumor Growth in Gastric Cancer by Inactivation of the ERK1/2 Pathway

Zhu H, Chen Y, Zhang J, Qian C, Qiu W, Shen H, Shen Z

OncoTargets and Therapy 2020, 13:5479-5491

Published Date: 12 June 2020

Original Research

miR-423 Promotes Breast Cancer Invasion by Activating NF-κB Signaling

Dai T, Zhao X, Li Y, Yu L, Li Y, Zhou X, Gong Q

OncoTargets and Therapy 2020, 13:5467-5478

Published Date: 12 June 2020

Original Research

A Novel lncRNA NONHSAT053785 Acts as an Independent Risk Factor for Intrahepatic Metastasis of Hepatocellular Carcinoma

Li Y, Li G, Chen X, Huang H, Liao L, Yuan T, Deng S

OncoTargets and Therapy 2020, 13:5455-5466

Published Date: 11 June 2020

Original Research

PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer

Zhang Y, Li J, Dong X, Meng D, Zhi X, Yuan L, Yao L

OncoTargets and Therapy 2020, 13:5443-5453

Published Date: 11 June 2020

Review

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy

Zhao Y, Li Y, Zhang R, Wang F, Wang T, Jiao Y

OncoTargets and Therapy 2020, 13:5429-5441

Published Date: 11 June 2020

Original Research

Noscapine Induces Apoptosis in Human Colon Cancer Cells by Regulating Mitochondrial Damage and Warburg Effect via PTEN/PI3K/mTOR Signaling Pathway

Tian X, Liu M, Huang X, Zhu Q, Liu W, Chen W, Zou Y, Cai Y, Huang S, Chen A, Zhan T, Huang M, Chen X, Han Z, Tan J

OncoTargets and Therapy 2020, 13:5419-5428

Published Date: 11 June 2020

Original Research

Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway

Fan J, Tian L, Huang S, Zhang J, Zhao B

OncoTargets and Therapy 2020, 13:5407-5417

Published Date: 11 June 2020

Original Research

Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model

Huang Z, Yu P, Tang J

OncoTargets and Therapy 2020, 13:5395-5405

Published Date: 11 June 2020

Original Research

Expression Level of Wnt5a Was Related to the Therapeutic Effects of First-Generation EGFR-TKIs

Zhang H, Yang X, Hu F, Li C, Xu J, Nie W, Shen Y, Lou Y, Han B, Zhong H, Zhang X

OncoTargets and Therapy 2020, 13:5387-5394

Published Date: 11 June 2020

Original Research

MiR-124-3p.1 Sensitizes Ovarian Cancer Cells to Mitochondrial Apoptosis Induced by Carboplatin

Deng X, Chen Y, Liu Z, Xu J

OncoTargets and Therapy 2020, 13:5375-5386

Published Date: 10 June 2020

Original Research

Brevilin A, a Natural Sesquiterpene Lactone Inhibited the Growth of Triple-Negative Breast Cancer Cells via Akt/mTOR and STAT3 Signaling Pathways

Qu Z, Lin Y, Mok DKW, Bian Q, Tai WCS, Chen S

OncoTargets and Therapy 2020, 13:5363-5373

Published Date: 10 June 2020

Original Research

MCTS1 Directly Binds to TWF1 and Synergistically Modulate Cyclin D1 and C-Myc Translation in Luminal A/B Breast Cancer Cells

Tian C, Zeng S, Luo J

OncoTargets and Therapy 2020, 13:5353-5361

Published Date: 10 June 2020

Original Research

A Retrospective Analysis of Primary Gastrointestinal Non-Hodgkin Lymphomas: Clinical Features, Prognostic Factors and Treatment Outcomes

Tian C, Li Y, Chen Z

OncoTargets and Therapy 2020, 13:5345-5352

Published Date: 10 June 2020

Original Research

lncRNA RHPN1-AS1 Promotes Ovarian Cancer Growth and Invasiveness Through Inhibiting miR-1299

Zhao L, Liu T, Zhang X, Zuo D, Liu C

OncoTargets and Therapy 2020, 13:5337-5344

Published Date: 10 June 2020

Original Research

Connexin 43 Modulates the Cellular Resistance to Paclitaxel via Targeting β-Tubulin in Triple-Negative Breast Cancer

Fu Y, Sun X, Gu Z, Zhuang Z

OncoTargets and Therapy 2020, 13:5323-5335

Published Date: 10 June 2020

Original Research

Ropivacaine Inhibits the Growth, Migration and Invasion of Gastric Cancer Through Attenuation of WEE1 and PI3K/AKT Signaling via miR-520a-3p

Zhang N, Xing X, Gu F, Zhou G, Liu X, Li B

OncoTargets and Therapy 2020, 13:5309-5321

Published Date: 9 June 2020

Original Research

A Novel Serum Exosomes-Based Biomarker hsa_circ_0002130 Facilitates Osimertinib-Resistance in Non-Small Cell Lung Cancer by Sponging miR-498

Ma J, Qi G, Li L

OncoTargets and Therapy 2020, 13:5293-5307

Published Date: 9 June 2020

Original Research

LncRNA PTTG3P Sponge Absorbs microRNA-155-5P to Promote Metastasis of Colorectal Cancer

Liu N, Dou L, Zhang X

OncoTargets and Therapy 2020, 13:5283-5291

Published Date: 9 June 2020

Original Research

Destruction of Neutrophil Extracellular Traps Promotes the Apoptosis and Inhibits the Invasion of Gastric Cancer Cells by Regulating the Expression of Bcl-2, Bax and NF-κB

Li R, Zou X, Zhu T, Xu H, Li X, Zhu L

OncoTargets and Therapy 2020, 13:5271-5281

Published Date: 9 June 2020

Original Research

p70S6K Promotes Acquired Resistance of Erlotinib Through Induction of Epithelial-Mesenchymal Transition in Non-Small Cell Lung Carcinoma

Li M, Chen H, Sun T, Ma Z, Chen X, Wu D, Huang W, Wang X

OncoTargets and Therapy 2020, 13:5257-5270

Published Date: 9 June 2020

Original Research

Antitumor Actions of Intratumoral Delivery of Membrane-Fused Mitochondria in a Mouse Model of Triple-Negative Breast Cancers

Chang JC, Chang HS, Wu YC, Cheng WL, Lin TT, Chang HJ, Chen ST, Liu CS

OncoTargets and Therapy 2020, 13:5241-5255

Published Date: 9 June 2020

Original Research

FOXA1 Promotes Cell Proliferation and Suppresses Apoptosis in HCC by Directly Regulating miR-212-3p/FOXA1/AGR2 Signaling Pathway

Yuan Z, Ye M, Qie J, Ye T

OncoTargets and Therapy 2020, 13:5231-5240

Published Date: 9 June 2020

Original Research

Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma

Zhao Y, He K, Zheng H, Sun M, Shi T, Zheng X, Shao D, Zhang H, Guan F, Li J, Chen L

OncoTargets and Therapy 2020, 13:5223-5230

Published Date: 9 June 2020

Original Research

β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways

Su P, Ahmad B, Zou K, Zou L

OncoTargets and Therapy 2020, 13:5207-5222

Published Date: 9 June 2020

Review

Tagraxofusp for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): A Brief Report on Emerging Data

Beziat G, Ysebaert L

OncoTargets and Therapy 2020, 13:5199-5205

Published Date: 9 June 2020

Original Research

Tumor Mutational Burden and PD-L1 Expression in Non-Small-Cell Lung Cancer (NSCLC) in Southwestern China

Ma Y, Li Q, Du Y, Chen W, Zhao G, Liu X, Ye L, Li H, Wang X, Liu J, Shen Z, Ma L, Zhou Y

OncoTargets and Therapy 2020, 13:5191-5198

Published Date: 8 June 2020

Original Research

P55PIK Regulates P53-Dependent Apoptosis in Cancer Cells by Interacting with P53 DNA-Specific Domain

Li C, Li W, Cheng X, Zhang D, Sun X, Zhou J, Zhou Y, Huang Y, Xia X, Ma Q, Su Z

OncoTargets and Therapy 2020, 13:5177-5190

Published Date: 8 June 2020

Original Research

CircNOL10 Acts as a Sponge of miR-135a/b-5p in Suppressing Colorectal Cancer Progression via Regulating KLF9

Zhang Y, Zhang Z, Yi Y, Wang Y, Fu J

OncoTargets and Therapy 2020, 13:5165-5176

Published Date: 8 June 2020

Original Research

Combined Evaluation of Preoperative Serum CEA and CA125 as an Independent Prognostic Biomarker in Patients with Early-Stage Cervical Adenocarcinoma

Huang G, Chen R, Lu N, Chen Q, Lv W, Li B

OncoTargets and Therapy 2020, 13:5155-5164

Published Date: 8 June 2020

Original Research

Low-Temperature Plasma Suppresses Proliferation and Induces Apoptosis in Lung Cancer Cells by Regulating the miR-203a/BIRC5 Axis

Yang Y, Li D, Li Y, Jiang Q, Sun R, Liu J, Wu F, Miao J, Ni L, Shi X, Huang C

OncoTargets and Therapy 2020, 13:5145-5153

Published Date: 8 June 2020

Original Research

Elevation in the Expression of circ_0079586 Predicts Poor Prognosis and Accelerates Progression in Glioma via Interactions with the miR-183-5p/MDM4 Signaling Pathway

Chen J, Liu T, Wang H, Wang Z, Lv Y, Zhao Y, Yang N, Yuan X

OncoTargets and Therapy 2020, 13:5135-5143

Published Date: 8 June 2020

Review

Profile of Polatuzumab Vedotin in the Treatment of Patients with Relapsed/Refractory Non-Hodgkin Lymphoma: A Brief Report on the Emerging Clinical Data

Sawalha Y, Maddocks K

OncoTargets and Therapy 2020, 13:5123-5133

Published Date: 8 June 2020

Original Research

CircFoxo3 Promotes Adriamycin Resistance Through Regulation of miR-199a-5p/ATP Binding Cassette Subfamily C Member 1 Axis in Hepatocellular Carcinoma

Huang W, Huang F, Feng C

OncoTargets and Therapy 2020, 13:5113-5122

Published Date: 8 June 2020

Review

Management of Refractory Pediatric Sarcoma: Current Challenges and Future Prospects

Pushpam D, Garg V, Ganguly S, Biswas B

OncoTargets and Therapy 2020, 13:5093-5112

Published Date: 8 June 2020

Original Research

Insulin-Like Growth Factor Binding Protein-2 Promotes Proliferation and Predicts Poor Prognosis in Hepatocellular Carcinoma

Ma Y, Cui D, Zhang Y, Han C, Wei W

OncoTargets and Therapy 2020, 13:5083-5092

Published Date: 8 June 2020

Original Research

Novel Nanocomplexes Targeting STAT3 Demonstrate Promising Anti-Ovarian Cancer Effects in vivo

Zhang X, Lu T, Ma Y, Li R, Pang Y, Mao H, Liu P

OncoTargets and Therapy 2020, 13:5069-5082

Published Date: 8 June 2020

Original Research

Diosgenin and GSK126 Produce Synergistic Effects on Epithelial–Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway

Liu S, Rong G, Li X, Geng L, Zeng Z, Jiang D, Yang J, Wei Y

OncoTargets and Therapy 2020, 13:5057-5067

Published Date: 8 June 2020

Original Research

Prognostic Value of the Preoperative Plasma D-Dimer Levels in Patients with Upper Tract Urothelial Carcinoma in a Retrospective Cohort Study

Chen X, Ji H, Wang J, Zhao G, Zheng B, Niu Z, He W

OncoTargets and Therapy 2020, 13:5047-5055

Published Date: 8 June 2020

Original Research

lncRNA MT1JP Suppresses Biological Activities of Breast Cancer Cells in vitro and in vivo by Regulating the miRNA-214/RUNX3 Axis

Ouyang Q, Cui Y, Yang S, Wei W, Zhang M, Zeng J, Qu F

OncoTargets and Therapy 2020, 13:5033-5046

Published Date: 4 June 2020

Original Research

Circulating Tumor DNA Correlates with Outcome in Metastatic Melanoma Treated by BRAF and MEK Inhibitors – Results of a Prospective Biomarker Study

Forschner A, Weißgraeber S, Hadaschik D, Schulze M, Kopp M, Kelkenberg S, Sinnberg T, Garbe C, Biskup S, Battke F

OncoTargets and Therapy 2020, 13:5017-5032

Published Date: 4 June 2020

Original Research

Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence

Chen PY, Li XD, Ma WN, Li H, Li MM, Yang XY, Li SY

OncoTargets and Therapy 2020, 13:4999-5016

Published Date: 3 June 2020

Original Research

Epoxycytochalasin H: An Endophytic Phomopsis Compound Induces Apoptosis in A2780 Cells Through Mitochondrial Damage and Endoplasmic Reticulum Stress

Wang J, Xu Z, Hu X, Yang Y, Su J, Liu Y, Zhou L, Qin J, Zhang D, Yu H

OncoTargets and Therapy 2020, 13:4987-4997

Published Date: 3 June 2020

Original Research

Identification of Aurora Kinase A as a Biomarker for Prognosis in Obesity Patients with Early Breast Cancer

Jiang J, Guo Z, Xu J, Sun T, Zheng X

OncoTargets and Therapy 2020, 13:4971-4985

Published Date: 3 June 2020

Original Research

Salinomycin and Sulforaphane Exerted Synergistic Antiproliferative and Proapoptotic Effects on Colorectal Cancer Cells by Inhibiting the PI3K/Akt Signaling Pathway in vitro and in vivo

Liu F, Lv RB, Liu Y, Hao Q, Liu SJ, Zheng YY, Li C, Zhu C, Wang M

OncoTargets and Therapy 2020, 13:4957-4969

Published Date: 3 June 2020

Original Research

HMGA1 Regulates the Stem Cell-Like Properties of Circulating Tumor Cells from GIST Patients via Wnt/β-Catenin Pathway

Chen M, Xu K, Li B, Wang N, Zhang Q, Chen L, Zhang D, Yang L, Xu Z, Xu H

OncoTargets and Therapy 2020, 13:4943-4956

Published Date: 11 June 2020

Original Research

Long Non-Coding RNA CRNDE Promotes Colorectal Carcinoma Cell Progression and Paclitaxel Resistance by Regulating miR-126-5p/ATAD2 Axis

Liu C, Hou J, Shan F, Wang L, Lu H, Ren T

OncoTargets and Therapy 2020, 13:4931-4942

Published Date: 2 June 2020

Original Research

Knockdown of lncRNA XIST Suppresses Cell Tumorigenicity in Human Non-Small Cell Lung Cancer by Regulating miR-142-5p/PAX6 Axis

Jiang Q, Xing W, Cheng J, Yu Y

OncoTargets and Therapy 2020, 13:4919-4929

Published Date: 2 June 2020

Corrigendum

Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells [Corrigendum]

Shi S, Zheng G, Yang C, Chen X, Yan Q, Jiang F, Jiang X, Xin Y, Jiang G

OncoTargets and Therapy 2020, 13:4917-4918

Published Date: 2 June 2020

Original Research

Silencing TCF4 Sensitizes Melanoma Cells to Vemurafenib Through Inhibiting GLUT3-Mediated Glycolysis

Liu C, He S, Zhang J, Li S, Chen J, Han C

OncoTargets and Therapy 2020, 13:4905-4915

Published Date: 29 May 2020

Original Research

CircRNA-PTN Sponges miR-326 to Promote Proliferation in Hepatocellular Carcinoma

Jia B, Yin X, Wang Y, Qian J, He Y, Yang C, Yu G, Guo B, Meng X

OncoTargets and Therapy 2020, 13:4893-4903

Published Date: 29 May 2020

Review

Ibrutinib in Chronic Lymphocytic Leukemia: Clinical Applications, Drug Resistance, and Prospects

Zhou H, Hu P, Yan X, Zhang Y, Shi W

OncoTargets and Therapy 2020, 13:4877-4892

Published Date: 29 May 2020

Original Research

Long Non-Coding RNA SNHG14 Contributes to the Development of Hepatocellular Carcinoma via Sponging miR-217

Xu X, Song F, Jiang X, Hong H, Fei Q, Jin Z, Zhu X, Dai B, Yang J, Sui C, Xu M

OncoTargets and Therapy 2020, 13:4865-4876

Published Date: 29 May 2020

Original Research

Six1 Overexpression Promotes Glucose Metabolism and Invasion Through Regulation of GLUT3, MMP2 and Snail in Thyroid Cancer Cells

Yang C, Xu W, Gong J, Chai F, Cui D, Liu Z

OncoTargets and Therapy 2020, 13:4855-4863

Published Date: 29 May 2020

Original Research

MiR-486-5p Act as a Biomarker in Endometrial Carcinoma: Promotes Cell Proliferation, Migration, Invasion by Targeting MARK1

Zheng X, Xu K, Zhu L, Mao M, Zhang F, Cui L

OncoTargets and Therapy 2020, 13:4843-4853

Published Date: 28 May 2020

Original Research

Inhibition of Serine Metabolism Promotes Resistance to Cisplatin in Gastric Cancer

Zhao X, Fu J, Tang W, Yu L, Xu W

OncoTargets and Therapy 2020, 13:4833-4842

Published Date: 29 May 2020

Review

Recent Advances of Magnetic Nanomaterials in the Field of Oncology

Li T, Yang C, Wei Z, Pei D, Jiang G

OncoTargets and Therapy 2020, 13:4825-4832

Published Date: 28 May 2020

Original Research

Overexpression of GAS6 Promotes Cell Proliferation and Invasion in Bladder Cancer by Activation of the PI3K/AKT Pathway

Mao S, Wu Y, Wang R, Guo Y, Bi D, Ma W, Zhang W, Zhang J, Yan Y, Yao X

OncoTargets and Therapy 2020, 13:4813-4824

Published Date: 27 May 2020

Original Research

LncRNA TTN-AS1 Regulates miR-524-5p and RRM2 to Promote Breast Cancer Progression

Feng H, Wang Q, Xiao W, Zhang B, Jin Y, Lu H

OncoTargets and Therapy 2020, 13:4799-4811

Published Date: 27 May 2020

Original Research

Circular RNA hsa_circ_0131242 Promotes Triple-Negative Breast Cancer Progression by Sponging hsa-miR-2682

Li Y, Shi P, Zheng T, Ying Z, Jiang D

OncoTargets and Therapy 2020, 13:4791-4798

Published Date: 27 May 2020

Original Research

ZNRD1-AS1 Promotes Nasopharyngeal Carcinoma Cell Invasion and Metastasis by Regulating the miR-335–ROCK1 Axis

Wang Q, Hu X, Du M, Lu Z, Yan K, Zhao D, Jiang N, Peng Y, He X, Yin L

OncoTargets and Therapy 2020, 13:4779-4790

Published Date: 27 May 2020

Original Research

Bufalin Induces Glioma Cell Death by Apoptosis or Necroptosis

LingHu HR, Luo H, Gang L

OncoTargets and Therapy 2020, 13:4767-4778

Published Date: 27 May 2020

Original Research

LncRNA XIST Promotes Growth of Human Chordoma Cells by Regulating miR-124-3p/iASPP Pathway

Hai B, Pan X, Du C, Mao T, Jia F, Liu Y, Ma Y, Liu X, Zhu B

OncoTargets and Therapy 2020, 13:4755-4765

Published Date: 26 May 2020

Original Research

FTY720 Suppresses Liver Tumor Growth and Metastasis by Reducing Circulating Regulating T Cells and Enhancing the Anti-Tumor Effect of Rapamycin

Li CX, Yang XX, Wang HW, Li XC, Ng KTP, Lo CM, Man K

OncoTargets and Therapy 2020, 13:4743-4754

Published Date: 26 May 2020

Original Research

miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1

Wu K, Yu Z, Tang Z, Wei W, Xie D, Xie Y, Xiao Q

OncoTargets and Therapy 2020, 13:4731-4742

Published Date: 26 May 2020

Original Research

Pre-mRNA Processing Factor 8 Accelerates the Progression of Hepatocellular Carcinoma by Regulating the PI3K/Akt Pathway

Wang S, Wang M, Wang B, Chen J, Cheng X, Sun X

OncoTargets and Therapy 2020, 13:4717-4730

Published Date: 26 May 2020

Corrigendum

Role of Robot-Assisted Partial Nephrectomy for Renal Cell Carcinomas in the Purpose of Nephron Sparing [Corrigendum]

Shao IH, Kan HC, Liu CY, Lin PH, Yu KJ, Pang ST, Wu CT, Chuang CK, Chang YH

OncoTargets and Therapy 2020, 13:4715-4716

Published Date: 26 May 2020

Case report

Pleomorphic Leiomyosarcoma of the Adrenal Gland in a Young Woman: A Case Report and Review of the Literature

Wang Y, Teng Y, Na S, Yuan Y

OncoTargets and Therapy 2020, 13:4705-4713

Published Date: 26 May 2020

Original Research

Sodium Butyrate Selectively Kills Cancer Cells and Inhibits Migration in Colorectal Cancer by Targeting Thioredoxin-1

Wang W, Fang D, Zhang H, Xue J, Wangchuk D, Du J, Jiang L

OncoTargets and Therapy 2020, 13:4691-4704

Published Date: 27 May 2020

Original Research

Loss of miR-204-5p Promotes Tumor Proliferation, Migration, and Invasion Through Targeting YWHAZ/PI3K/AKT Pathway in Esophageal Squamous Cell Carcinoma

Shen Z, Chai T, Luo F, Liu Z, Xu H, Zhang P, Kang M, Chen S

OncoTargets and Therapy 2020, 13:4679-4690

Published Date: 26 May 2020

Original Research

Knockdown of FAM83D Enhances Radiosensitivity in Coordination with Irradiation by Inhibiting EMT via the Akt/GSK-3β/Snail Signaling Pathway in Human Esophageal Cancer Cells

Yang XX, Ma M, Sang M, Zhang X, Zou N, Zhu S

OncoTargets and Therapy 2020, 13:4665-4678

Published Date: 26 May 2020

Original Research

Deficiency of PTEN and CDKN2A Tumor-Suppressor Genes in Conventional and Chondroid Chordomas: Molecular Characteristics and Clinical Relevance

Yang C, Sun J, Yong L, Liang C, Liu T, Xu Y, Yang J, Liu X

OncoTargets and Therapy 2020, 13:4649-4663

Published Date: 25 May 2020

Original Research

SRC Promotes Tamoxifen Resistance in Breast Cancer via Up-Regulating SIRT1

Zhou J, Xu M, Le K, Ming J, Guo H, Ruan S, Huang T

OncoTargets and Therapy 2020, 13:4635-4647

Published Date: 25 May 2020

Original Research

The Value of ABO Blood Group and Complete Blood Count for the Prognosis Analysis of Gastric Cancer Patients

Sun X, Ai L, Feng Y

OncoTargets and Therapy 2020, 13:4627-4633

Published Date: 25 May 2020

Original Research

SASH1 Suppresses the Proliferation and Invasion of Human Skin Squamous Cell Carcinoma Cells via Inhibiting Akt Cascade

Chen S, Zhang Y, Lei S, Zhou F

OncoTargets and Therapy 2020, 13:4617-4625

Published Date: 25 May 2020

Original Research

Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung Cancer

Bai J, Jiao WY

OncoTargets and Therapy 2020, 13:4607-4616

Published Date: 22 May 2020

Original Research

Long Non-Coding RNA 691 Regulated PTEN/PI3K/AKT Signaling Pathway in Osteosarcoma Through miRNA-9-5p

Yao P, Ni Y, Liu C

OncoTargets and Therapy 2020, 13:4597-4606

Published Date: 22 May 2020

Case report

Primary Resistance to Brigatinib in a Patient with Lung Adenocarcinoma Harboring ALK G1202R Mutation and LIPI-NTRK1 Rearrangement

Xiao Z, Huang X, Xie B, Xie W, Huang M, Lin L

OncoTargets and Therapy 2020, 13:4591-4595

Published Date: 22 May 2020

Original Research

Significance of Tumor-Infiltrating Immune Cells in the Prognosis of Colon Cancer

Wu D, Ding Y, Wang T, Cui P, Huang L, Min Z, Xu M

OncoTargets and Therapy 2020, 13:4581-4589

Published Date: 22 May 2020

Original Research

LncRNA SNHG16 Promotes the Progression of Laryngeal Squamous Cell Carcinoma by Mediating miR-877-5p/FOXP4 Axis

Wang X, Liu L, Zhao W, Li Q, Wang G, Li H

OncoTargets and Therapy 2020, 13:4569-4579

Published Date: 22 May 2020

Original Research

Prognostic Significance of Elevated Preoperative Serum CA125 Levels After Curative Hepatectomy for Hepatocellular Carcinoma

Huang Y, Zeng J, Liu T, Lin X, Guo P, Zeng J, Zhou W, Liu J

OncoTargets and Therapy 2020, 13:4559-4567

Published Date: 22 May 2020

Original Research

CircHIPK3 Facilitates the G2/M Transition in Prostate Cancer Cells by Sponging miR-338-3p

Liu F, Fan Y, Ou L, Li T, Fan J, Duan L, Yang J, Luo C, Wu X

OncoTargets and Therapy 2020, 13:4545-4558

Published Date: 22 May 2020

Original Research

Circ_0001023 Promotes Proliferation and Metastasis of Gastric Cancer Cells Through miR-409-3p/PHF10 Axis

Wang Y, Zhang J, Chen X, Gao L

OncoTargets and Therapy 2020, 13:4533-4544

Published Date: 22 May 2020

Original Research

lncRNA HAND2-AS1 Regulates Prostate Cancer Cell Growth Through Targeting the miR-106a-5p/RBM24 Axis

Wei P, Yang J, Zhang D, Cui M, Li L

OncoTargets and Therapy 2020, 13:4523-4531

Published Date: 21 May 2020

Original Research

Circular RNA Gprc5a Promotes HCC Progression by Activating YAP1/TEAD1 Signalling Pathway by Sponging miR-1283

Lin Y, Huang G, Jin H, Jian Z

OncoTargets and Therapy 2020, 13:4509-4521

Published Date: 21 May 2020

Corrigendum

Downregulation of miR-486-5p Enhances the Anti-Tumor Effect of 5-Fluorouracil on Pancreatic Cancer Cells [Corrigendum]

Wang W, Liu B, Sun S, Lan L, Chen Y, Han S, Li X, Li Z

OncoTargets and Therapy 2020, 13:4507-4508

Published Date: 21 May 2020

Original Research

MiR-181c-5p Mitigates Tumorigenesis in Cervical Squamous Cell Carcinoma via Targeting Glycogen Synthase Kinase 3β Interaction Protein (GSKIP)

Li N, Cheng C, Wang T

OncoTargets and Therapy 2020, 13:4495-4505

Published Date: 21 May 2020

Original Research

miR-381 Mediates the Development of Head and Neck Squamous Cell Carcinoma via Targeting STC2

Ma HF, Lv GX, Zhang DH

OncoTargets and Therapy 2020, 13:4485-4493

Published Date: 21 May 2020

Review

Advances and Prospects of Vasculogenic Mimicry in Glioma: A Potential New Therapeutic Target?

Cai H, Liu W, Liu X, Li Z, Feng T, Xue Y, Liu Y

OncoTargets and Therapy 2020, 13:4473-4483

Published Date: 21 May 2020

Case report

The Combined Use of Chemotherapy and Radiotherapy with PD-1 Inhibitor, Pembrolizumab, in Advanced Cervical Cancer: A Case Report

Lyu M, Shen Y, Beharee N, Lu J, Deng F, Wang J

OncoTargets and Therapy 2020, 13:4465-4471

Published Date: 21 May 2020

Original Research

Effectiveness and Safety of Apatinib in Patients with Advanced or Metastatic Adenocarcinoma of Stomach or Gastroesophageal Junction: A Prospective Observation Study

Shen B, Jiang H, Wang L, Qian J, Shu Y, Chen P, Mao G, Liu B, Zhang X, Liu C, Wu J, Li X, Cai W, Shen W, Wang Q, He J, Hua D, Zhang Z, Zhang Y, Feng J

OncoTargets and Therapy 2020, 13:4457-4464

Published Date: 20 May 2020

Original Research

Metformin Promotes Beclin1-Dependent Autophagy to Inhibit the Progression of Gastric Cancer

Liu S, Yue C, Chen H, Chen Y, Li G

OncoTargets and Therapy 2020, 13:4445-4455

Published Date: 19 May 2020

Original Research

The Long Noncoding RNA ZFAS1 Potentiates the Development of Hepatocellular Carcinoma via the microRNA-624/MDK/ERK/JNK/P38 Signaling Pathway

Duan R, Li C, Wang F, Han F, Zhu L

OncoTargets and Therapy 2020, 13:4431-4444

Published Date: 19 May 2020

Review

Review of Research on the Role of Irisin in Tumors

Zhang D, Tan X, Tang N, Huang F, Chen Z, Shi G

OncoTargets and Therapy 2020, 13:4423-4430

Published Date: 19 May 2020

Original Research

Identification of Pannexin 2 as a Novel Marker Correlating with Ferroptosis and Malignant Phenotypes of Prostate Cancer Cells

Liao D, Yang G, Yang Y, Tang X, Huang H, Shao J, Pan Q

OncoTargets and Therapy 2020, 13:4411-4421

Published Date: 19 May 2020

Original Research

LncRNA ZNF667-AS1 Promotes ABLIM1 Expression by Adsorbing microRNA-1290 to Suppress Nasopharyngeal Carcinoma Cell Progression

Chen X, Huang Y, Shi D, Nie C, Luo Y, Guo L, Zou Y, Xie C

OncoTargets and Therapy 2020, 13:4397-4409

Published Date: 20 May 2020

Original Research

Prognostic Value of Plasma HER2 Gene Copy Number in HER2-Positive Metastatic Breast Cancer Treated with First-Line Trastuzumab

Ran R, Huang W, Liu Y, Shao L, Liu X, Niu Y, Kong W, Bo S, Rugo HS, Lu S, Li H

OncoTargets and Therapy 2020, 13:4385-4395

Published Date: 19 May 2020

Original Research

FAM110B Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through Inactivating Wnt/β-Catenin Signaling

Xie M, Cai L, Li J, Zhao J, Guo Y, Hou Z, Zhang X, Tian H, Li A, Miao Y

OncoTargets and Therapy 2020, 13:4373-4384

Published Date: 19 May 2020

Original Research

A Combination of circRNAs as a Diagnostic Tool for Discrimination of Papillary Thyroid Cancer

Shi E, Ye J, Zhang R, Ye S, Zhang S, Wang Y, Cao Y, Dai W

OncoTargets and Therapy 2020, 13:4365-4372

Published Date: 19 May 2020

Case report

Anti-PD-1 Therapy Achieved Disease Control After Multiline Chemotherapy in Unresectable KRAS-Positive Hepatoid Lung Adenocarcinoma: A Case Report and Literature Review

Chen L, Han X, Gao Y, Zhao Q, Wang Y, Jiang Y, Liu S, Wu X, Miao L

OncoTargets and Therapy 2020, 13:4359-4364

Published Date: 19 May 2020

Original Research

MiR-1193 Inhibits the Malignancy of Cervical Cancer Cells by Targeting Claudin 7 (CLDN7)

Zhang B, Lin Y, Bao Q, Zheng Y, Lan L

OncoTargets and Therapy 2020, 13:4349-4358

Published Date: 19 May 2020

Original Research

A 5-Gene Stemness Score for Rapid Determination of Risk in Multiple Myeloma

Bai H, Chen B

OncoTargets and Therapy 2020, 13:4339-4348

Published Date: 18 May 2020

Original Research

Vital and Distinct Roles of H2A.Z Isoforms in Hepatocellular Carcinoma

Tang S, Huang X, Wang X, Zhou X, Huang H, Qin L, Tao H, Wang Q, Tao Y

OncoTargets and Therapy 2020, 13:4319-4337

Published Date: 18 May 2020

Original Research

SP1-Mediated Upregulation of lncRNA LINC01614 Functions a ceRNA for miR-383 to Facilitate Glioma Progression Through Regulation of ADAM12

Wang H, Wu J, Guo W

OncoTargets and Therapy 2020, 13:4305-4318

Published Date: 18 May 2020

Review

Long Noncoding RNAs in Diffuse Large B-Cell Lymphoma: Current Advances and Perspectives

Huang X, Qian W, Ye X

OncoTargets and Therapy 2020, 13:4295-4303

Published Date: 18 May 2020

Original Research

Long Non-Coding RNA SNHG16 Activates USP22 Expression to Promote Colorectal Cancer Progression by Sponging miR-132-3p

He X, Ma J, Zhang M, Cui J, Yang H

OncoTargets and Therapy 2020, 13:4283-4294

Published Date: 18 May 2020

Original Research

Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer

Jiang Z, Cheng P, Luo B, Huang J

OncoTargets and Therapy 2020, 13:4271-4282

Published Date: 18 May 2020

Original Research

MicroRNA-939 Directly Targets HDGF to Inhibit the Aggressiveness of Prostate Cancer via Deactivation of the WNT/β-Catenin Pathway

Situ J, Zhang H, Jin Z, Li K, Mao Y, Huang W

OncoTargets and Therapy 2020, 13:4257-4270

Published Date: 18 May 2020

Case report

Response to Anti-HER2-Based Treatment in a Patient with Bladder Adenocarcinoma Harboring HER2 Amplification and S310F Mutation Discovered by Next-Generation Sequencing: A Case Report

Wang X, Hu W, Xie L

OncoTargets and Therapy 2020, 13:4249-4255

Published Date: 18 May 2020

Original Research

Rapamycin Reduces Cervical Cancer Cells Viability in Hypoxic Condition: Investigation of the Role of Autophagy and Apoptosis

Rezazadeh D, Norooznezhad AH, Mansouri K, Jahani M, Mostafaie A, Mohammadi MH, Modarressi MH

OncoTargets and Therapy 2020, 13:4239-4247

Published Date: 18 May 2020

Original Research

MicroRNA-374b-5p Functions as a Tumor Suppressor in Non-Small Cell Lung Cancer by Targeting FOXP1 and Predicts Prognosis of Cancer Patients

Li J, Zhang X, Tang J, Gong C

OncoTargets and Therapy 2020, 13:4229-4237

Published Date: 15 May 2020

Original Research

Ingredients, Anti-Liver Cancer Effects and the Possible Mechanism of DWYG Formula Based on Network Prediction

Li Y, Li HM, Li ZC, Yang M, Xie RF, Ye ZH, Gao X, Zhou X

OncoTargets and Therapy 2020, 13:4213-4227

Published Date: 15 May 2020

Original Research

DNMT1 Enhances the Radiosensitivity of HPV-Positive Head and Neck Squamous Cell Carcinomas via Downregulating SMG1

Zhang C, Mi J, Deng Y, Deng Z, Long D, Liu Z

OncoTargets and Therapy 2020, 13:4201-4211

Published Date: 15 May 2020

Original Research

Inhibition of HMGB1 Overcomes Resistance to Radiation and Chemotherapy in Nasopharyngeal Carcinoma

Zhu X, Cong J, Lin Z, Sun J, Yang B, Li A

OncoTargets and Therapy 2020, 13:4189-4199

Published Date: 14 May 2020

Case report

Responses to ALK Inhibitor Treatments in a Patient with Non-Small Cell Lung Cancer Harboring a Novel HPCAL1-ALK Fusion Variant: A Case Report

Wang R, Qin J, Fan Y, Li Z, Chen C, Su W

OncoTargets and Therapy 2020, 13:4183-4187

Published Date: 14 May 2020

Original Research

Metformin Suppresses the Proliferation and Promotes the Apoptosis of Colon Cancer Cells Through Inhibiting the Expression of Long Noncoding RNA-UCA1

Guo J, Li Y, Duan H, Yuan L

OncoTargets and Therapy 2020, 13:4169-4181

Published Date: 14 May 2020

Original Research

The microRNA miR-3174 Suppresses the Expression of ADAM15 and Inhibits the Proliferation of Patient-Derived Bladder Cancer Cells

Yu C, Wang Y, Liu T, Sha K, Song Z, Zhao M, Wang X

OncoTargets and Therapy 2020, 13:4157-4168

Published Date: 14 May 2020

Original Research

Interfering Human Papillomavirus E6/E7 Oncogenes in Cervical Cancer Cells Inhibits the Angiogenesis of Vascular Endothelial Cells via Increasing miR-377 in Cervical Cancer Cell-Derived Microvesicles

Zhang Y, Liu Y, Guo X, Hu Z, Shi H

OncoTargets and Therapy 2020, 13:4145-4155

Published Date: 13 May 2020

Original Research

Clinical Value of Tumor Marker Index Based on Preoperative CYFRA 21-1 and SCC-Ag in the Evaluation of Prognosis and Treatment Effectiveness in Patients with Esophageal Squamous Cell Carcinoma

Yin N, Liu W

OncoTargets and Therapy 2020, 13:4135-4143

Published Date: 13 May 2020

Original Research

Rab18 Regulates Proliferation, Invasion and Cisplatin Sensitivity Through STAT3 Signaling in Head and Neck Squamous Cell Carcinoma

Ji X, Guo X, Wang Y, Li X, Li H

OncoTargets and Therapy 2020, 13:4123-4134

Published Date: 13 May 2020

Original Research

Bruton’s Tyrosine Kinase (BTK) Inhibitor (Ibrutinib)-Suppressed Migration and Invasion of Prostate Cancer

Zhu Z, Ling L, Qi L, Chong Y, Xue L

OncoTargets and Therapy 2020, 13:4113-4122

Published Date: 13 May 2020

Corrigendum

Bioinformatics Analysis to Reveal Potential Differentially Expressed Long Non-Coding RNAs and Genes Associated with Tumour Metastasis in Lung Adenocarcinoma [Corrigendum]

Yao X, Zhang H, Tang S, Zheng X, Jiang L

OncoTargets and Therapy 2020, 13:4111-4112

Published Date: 13 May 2020

Original Research

MicroRNA-766 Promotes The Proliferation, Migration And Invasion, And Inhibits The Apoptosis Of Cutaneous Squamous Cell Carcinoma Cells By Targeting PDCD5

Liu P, Shi L, Ding Y, Luan J, Shan X, Li Q, Zhang S

OncoTargets and Therapy 2020, 13:4099-4110

Published Date: 13 May 2020

Original Research

MiR-153-5p Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Paclitaxel by Inducing G2M Phase Arrest

Wang Y, Wu N, Zhang J, Wang H, Men X

OncoTargets and Therapy 2020, 13:4089-4097

Published Date: 12 May 2020

Review

Current Molecular Targeted Agents for Advanced Gastric Cancer

Nie S, Yang G, Lu H

OncoTargets and Therapy 2020, 13:4075-4088

Published Date: 12 May 2020

Original Research

miR-383 Down-Regulates the Oncogene CIP2A to Influence Glioma Proliferation and Invasion

Zhang S, Wang K

OncoTargets and Therapy 2020, 13:4063-4074

Published Date: 12 May 2020

Original Research

lncRNA MALAT1 Promotes EMT Process and Cisplatin Resistance of Oral Squamous Cell Carcinoma via PI3K/AKT/m-TOR Signal Pathway

Wang R, Lu X, Yu R

OncoTargets and Therapy 2020, 13:4049-4061

Published Date: 12 May 2020

Original Research

Elevated Levels of circRUNX1 in Colorectal Cancer Promote Cell Growth and Metastasis via miR-145-5p/IGF1 Signalling

Chen ZL, Li XN, Ye CX, Chen HY, Wang ZJ

OncoTargets and Therapy 2020, 13:4035-4048

Published Date: 12 May 2020

Review

Optimal Management of First-Line Advanced Renal Cell Carcinoma: Focus on Pembrolizumab

Singh A, Singh I, Singh N, Puzanov I

OncoTargets and Therapy 2020, 13:4021-4034

Published Date: 13 May 2020

Erratum

Efficacy of sorafenib after liver transplantation in patients with primary hepatic carcinoma exceeding the Milan criteria: a preliminary study [Expression of concern] [Erratum]

Huang L, Li G, Zhu J, Li Z, Li T, Leng X

OncoTargets and Therapy 2020, 13:4019-4020

Published Date: 12 May 2020

Original Research

Plasma Exosomal Long Noncoding RNA lnc-SLC2A12-10:1 as a Novel Diagnostic Biomarker for Gastric Cancer

Zheng P, Zhang H, Gao H, Sun J, Li J, Zhang X, Gao L, Ma P, Li S

OncoTargets and Therapy 2020, 13:4009-4018

Published Date: 11 May 2020

Original Research

SLC39A4 as a Novel Prognosis Marker Promotes Tumor Progression in Esophageal Squamous Cell Carcinoma

Xia C, Chen X, Li J, Chen P

OncoTargets and Therapy 2020, 13:3999-4008

Published Date: 11 May 2020

Original Research

Circ-OXCT1 Suppresses Gastric Cancer EMT and Metastasis by Attenuating TGF-β Pathway Through the Circ-OXCT1/miR-136/SMAD4 Axis

Liu J, Dai X, Guo X, Cheng A, Mac SM, Wang Z

OncoTargets and Therapy 2020, 13:3987-3998

Published Date: 11 May 2020

Original Research

Long Non-Coding RNA NEAT1 Serves as Sponge for miR-365a-3p to Promote Gastric Cancer Progression via Regulating ABCC4

Gao M, Liu L, Zhang D, Yang Y, Chang Z

OncoTargets and Therapy 2020, 13:3977-3985

Published Date: 11 May 2020

Corrigendum

Antitumor Activity of Larotrectinib in Tumors Harboring NTRK Gene Fusions: A Short Review on the Current Evidence [Corrigendum]

Ricciuti B, Genova C, Crinò L, Libra M, Leonardi GC

OncoTargets and Therapy 2020, 13:3975-3976

Published Date: 11 May 2020

Original Research

High Expression of hsa_circRNA_001387 in Nasopharyngeal Carcinoma and the Effect on Efficacy of Radiotherapy

Shuai M, Huang L

OncoTargets and Therapy 2020, 13:3965-3973

Published Date: 8 May 2020

Original Research

Inhibition of Aurora Kinase A by Alisertib Reduces Cell Proliferation and Induces Apoptosis and Autophagy in HuH-6 Human Hepatoblastoma Cells

Tan J, Xu W, Lei L, Liu H, Wang H, Cao X, Xu M

OncoTargets and Therapy 2020, 13:3953-3963

Published Date: 8 May 2020

Original Research

Clinicopathological, Immunohistochemical and Molecular Genetic Study on Epithelioid Glioblastoma: A Series of Fifteen Cases with Literature Review

Zeng Y, Zhu X, Wang Y, Liu B, Yang X, Wang Q, Du J, Ma Y, Lin L, Fu P, Xiao H, Guo QN

OncoTargets and Therapy 2020, 13:3943-3952

Published Date: 8 May 2020

Original Research

NR1D2 Accelerates Hepatocellular Carcinoma Progression by Driving the Epithelial-to-Mesenchymal Transition

Tong H, Liu X, Li T, Qiu W, Peng C, Shen B, Zhu Z

OncoTargets and Therapy 2020, 13:3931-3942

Published Date: 8 May 2020

Review

Pulmonary Lymphoepithelioma-Like Carcinoma: A Mini-Review

Hu Y, Ren S, Liu Y, Han W, Liu W

OncoTargets and Therapy 2020, 13:3921-3929

Published Date: 11 May 2020

Original Research

Dinutuximab Synergistically Enhances the Cytotoxicity of Natural Killer Cells to Retinoblastoma Through the Perforin-Granzyme B Pathway

Wang H, Yang J, Pan H, Tai MC, Maher MH, Jia R, Ge S, Lu L

OncoTargets and Therapy 2020, 13:3903-3920

Published Date: 8 May 2020

Review

The Role of DLLs in Cancer: A Novel Therapeutic Target

Xiu MX, Liu YM, Kuang B

OncoTargets and Therapy 2020, 13:3881-3901

Published Date: 7 May 2020

Original Research

Hsa_circ_0043265 Suppresses Proliferation, Metastasis, EMT and Promotes Apoptosis in Non-Small Cell Lung Cancer Through miR-25-3p/FOXP2 Pathway

Ren T, Liu C, Hou J, Shan F

OncoTargets and Therapy 2020, 13:3867-3880

Published Date: 7 May 2020

Original Research

Long Non-Coding RNA OIP5-AS1 Knockdown Enhances CDDP Sensitivity in Osteosarcoma via miR-377-3p/FOSL2 Axis

Liu L, Wang S

OncoTargets and Therapy 2020, 13:3853-3866

Published Date: 7 May 2020

Original Research

Identification of Aberrantly Expressed Genes in Murine Glioblastoma During Radiotherapy via Bioinformatic Data Mining

Zhao X, Li C, Liu L, Zou H, Li K

OncoTargets and Therapy 2020, 13:3839-3851

Published Date: 6 May 2020

Original Research

The Synergistic Antitumor Activity of Chidamide in Combination with Bortezomib on Gastric Cancer

Zhang W, Niu J, Ma Y, Yang X, Cao H, Guo H, Bao F, Haw A, Chen Y, Sun K

OncoTargets and Therapy 2020, 13:3823-3837

Published Date: 6 May 2020

Original Research

Microsatellite Instability-Related ACVR2A Mutations Partially Account for Decreased Lymph Node Metastasis in MSI-H Gastric Cancers

Zhao L, Zhang J, Qu X, Yang Y, Gong Z, Yang Y, Wu Z, Guo W

OncoTargets and Therapy 2020, 13:3809-3821

Published Date: 5 May 2020

Original Research

GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways

Zha B, Qiu P, Zhang C, Li X, Chen Z

OncoTargets and Therapy 2020, 13:3801-3808

Published Date: 6 May 2020

Original Research

miR-145 Inhibits Th9 Cell Differentiation by Suppressing Activation of the PI3K/Akt/mTOR/p70S6K/HIF-1α Pathway in Malignant Ascites from Liver Cancer

Huang YY, Jiang HX, Shi QY, Qiu X, Wei X, Zhang XL, Qin SY

OncoTargets and Therapy 2020, 13:3789-3800

Published Date: 5 May 2020

Original Research

The Anti-Breast Cancer Effect and Mechanism of Glimepiride-Metformin Adduct

Long L, Hu X, Li X, Zhou D, Shi Y, Wang L, Zeng H, Yu X, Zhou W

OncoTargets and Therapy 2020, 13:3777-3788

Published Date: 4 May 2020

Original Research

Histamine H3 Receptor Promotes Cell Survival via Regulating PKA/CREB/CDKN1A Signal Pathway in Hepatocellular Carcinoma

Zhang C, Yu Y, Ma L, Fu P

OncoTargets and Therapy 2020, 13:3765-3776

Published Date: 4 May 2020

Original Research

Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells

Wu D, Liu T, Deng S, Han R, Zhang T, Li J, Xu Y

OncoTargets and Therapy 2020, 13:3751-3763

Published Date: 4 May 2020

Original Research

Targeting eIF3f Suppresses the Growth of Prostate Cancer Cells by Inhibiting Akt Signaling

Li J, Yu W, Ge J, Zhang J, Wang Y, Wang P, Shi G

OncoTargets and Therapy 2020, 13:3739-3750

Published Date: 4 May 2020

Original Research

Circular RNA circTUBGCP3 Is Up-Regulated and Promotes Cell Proliferation, Migration and Survivability via Sponge mir-30b in Osteosarcoma

Xu Y, Yao T, Huang K, Liu G, Huang Y, Gao J, Ye H, Shen S, Ma J

OncoTargets and Therapy 2020, 13:3729-3737

Published Date: 4 May 2020

Original Research

CircLARP4 Suppresses Cell Proliferation, Invasion and Glycolysis and Promotes Apoptosis in Non-Small Cell Lung Cancer by Targeting miR-135b

Lu H, Guo Q, Mao G, Zhu J, Li F

OncoTargets and Therapy 2020, 13:3717-3728

Published Date: 4 May 2020

Original Research

Minicircle DNA-Mediated CAR T Cells Targeting CD44 Suppressed Hepatocellular Carcinoma Both in vitro and in vivo

Wang H, Ye X, Ju Y, Cai Z, Wang X, Du P, Zhang M, Li Y, Cai J

OncoTargets and Therapy 2020, 13:3703-3716

Published Date: 4 May 2020

Original Research

Circular RNA circ_0007142 Facilitates Colorectal Cancer Progression by Modulating CDC25A Expression via miR-122-5p

Yin W, Xu J, Li C, Dai X, Wu T, Wen J

OncoTargets and Therapy 2020, 13:3689-3701

Published Date: 1 May 2020

Original Research

SCAMP3 Promotes Glioma Proliferation and Indicates Unfavorable Prognosis via Multiple Pathways

Li C, Zhang Z, Lv P, Zhan Y, Zhong Q

OncoTargets and Therapy 2020, 13:3677-3687

Published Date: 1 May 2020

Original Research

Downregulation of miR-575 Inhibits the Tumorigenesis of Gallbladder Cancer via Targeting p27 Kip1

Qin Y, Mi W, Huang C, Li J, Zhang Y, Fu Y

OncoTargets and Therapy 2020, 13:3667-3676

Published Date: 1 May 2020

Original Research

Long Noncoding RNA MALAT1 Promotes the Development of Colon Cancer by Regulating miR-101-3p/STC1 Axis

Luan C, Li Y, Liu Z, Zhao C

OncoTargets and Therapy 2020, 13:3653-3665

Published Date: 30 April 2020

Original Research

Long Non-Coding RNA NNT-AS1 Contributes to Cisplatin Resistance via miR-1236-3p/ATG7 Axis in Lung Cancer Cells

Wang H, Guo M, Ding D, Yang F, Chen Z

OncoTargets and Therapy 2020, 13:3641-3652

Published Date: 30 April 2020

Original Research

Tetrandrine Reverses Paclitaxel Resistance in Human Ovarian Cancer via Inducing Apoptosis, Cell Cycle Arrest Through β-Catenin Pathway

Jiang L, Hou R

OncoTargets and Therapy 2020, 13:3631-3639

Published Date: 30 April 2020

Original Research

Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway

Li J, Wu D, Han R, Yu Y, Deng S, Liu T, Zhang T, Xu Y

OncoTargets and Therapy 2020, 13:3619-3629

Published Date: 29 April 2020

Original Research

MiR-138 Suppresses the PDK1 Expression to Decrease the Oxaliplatin Resistance of Colorectal Cancer

Wang Y, Zhang D, Li Y, Fang F

OncoTargets and Therapy 2020, 13:3607-3618

Published Date: 29 April 2020

Original Research

Phosphoproteomics Reveals Key Regulatory Kinases and Modulated Pathways Associated with Ovarian Cancer Tumors

Hu Y, Sun L, Zhang Y, Lang J, Rao J

OncoTargets and Therapy 2020, 13:3595-3605

Published Date: 29 April 2020

Original Research

BCAT1 Overexpression Promotes Proliferation, Invasion, and Wnt Signaling in Non-Small Cell Lung Cancers

Lin X, Tan S, Fu L, Dong Q

OncoTargets and Therapy 2020, 13:3583-3594

Published Date: 29 April 2020

Review

Metastatic Hormone-sensitive Prostate Cancer: Current Perspective on the Evolving Therapeutic Landscape

Hall ME, Huelster HL, Luckenbaugh AN, Laviana AA, Keegan KA, Klaassen Z, Moses KA, Wallis CJD

OncoTargets and Therapy 2020, 13:3571-3581

Published Date: 29 April 2020

Original Research

MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib

Yang S, Wang M, Yang L, Li Y, Ma Y, Peng X, Li X, Li B, Jin H, Li H

OncoTargets and Therapy 2020, 13:3557-3570

Published Date: 28 April 2020

Review

Peptide Receptor Radionuclide Therapy for the Treatment of Pancreatic Neuroendocrine Tumors: Recent Insights

Starr JS, Sonbol MB, Hobday TJ, Sharma A, Kendi AT, Halfdanarson TR

OncoTargets and Therapy 2020, 13:3545-3555

Published Date: 28 April 2020

Original Research

An Oncolytic Vaccinia Virus Armed with GM-CSF and IL-24 Double Genes for Cancer Targeted Therapy

Deng L, Yang X, Fan J, Ding Y, Peng Y, Xu D, Huang B, Hu Z

OncoTargets and Therapy 2020, 13:3535-3544

Published Date: 28 April 2020

Original Research

Long Noncoding RNA H19 Facilitates Small Cell Lung Cancer Tumorigenesis Through miR-140-5p/FGF9 Axis

Li X, Lv F, Li F, Du M, Liang Y, Ju S, Liu Z, Wang B, Gao Y

OncoTargets and Therapy 2020, 13:3525-3534

Published Date: 28 April 2020

Original Research

Mitofusin1 Is a Major Mediator in Glucose-Induced Epithelial-to-Mesenchymal Transition in Lung Adenocarcinoma Cells

Liu X, Feng C, Wei G, Kong W, Meng H, Du Y, Li J

OncoTargets and Therapy 2020, 13:3511-3523

Published Date: 24 April 2020

Original Research

FNDC3B, Targeted by miR-125a-5p and miR-217, Promotes the Proliferation and Invasion of Colorectal Cancer Cells via PI3K/mTOR Signaling

Li Y, Yang J, Wang H, Qiao W, Guo Y, Zhang S, Guo Y

OncoTargets and Therapy 2020, 13:3501-3510

Published Date: 30 April 2020

Original Research

Downregulation of OSR1 Promotes Colon Adenocarcinoma Progression via FAK-Mediated Akt and MAPK Signaling

Zhang F, Jiang Z

OncoTargets and Therapy 2020, 13:3489-3500

Published Date: 24 April 2020

Original Research

ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer

Weng M, Zhang H, Hou W, Sun Z, Zhong J, Miao C

OncoTargets and Therapy 2020, 13:3477-3488

Published Date: 24 April 2020

Original Research

ATF3 Demethylation Promotes the Transcription of ARL4C, Which Acts as a Tumor Suppressor in Human Breast Cancer

Li L, Sun RM, Jiang GQ

OncoTargets and Therapy 2020, 13:3467-3476

Published Date: 23 April 2020

Original Research

The miR-1224-5p/ELF3 Axis Regulates Malignant Behaviors of Pancreatic Cancer via PI3K/AKT/Notch Signaling Pathways

Kong L, Liu P, Zheng M, Wang Z, Gao Y, Liang K, Wang H, Tan X

OncoTargets and Therapy 2020, 13:3449-3466

Published Date: 23 April 2020

Original Research

The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer

Zhang Y, Zheng A, Lu H, Jin Z, Peng Z, Jin F

OncoTargets and Therapy 2020, 13:3437-3448

Published Date: 23 April 2020

Case report

Essential Thrombocythaemia with Concomitant Waldenström Macroglobulinaemia: Case Report and Literature Review

Lu N, Neoh CL, Ruan Z, Zhao L, Ying L, Zhang X, Chen S, Xu L

OncoTargets and Therapy 2020, 13:3431-3435

Published Date: 23 April 2020

Case report

Case Report of Anti-CD123 Chimeric Antigen Receptor T-Cell Therapy Followed by Radiotherapy for a Recurrence of Blastic Plasmacytoid Dendritic Cell Neoplasm After Allogeneic Hematopoietic Stem Cell Transplantation

Jiang Y, Li Q, Yuan T, Jiang Y, Deng Q

OncoTargets and Therapy 2020, 13:3425-3430

Published Date: 22 April 2020

Original Research

Effects of miR-330-3p on Invasion, Migration and EMT of Gastric Cancer Cells by Targeting PRRX1-Mediated Wnt/β-Catenin Signaling Pathway

Ma B, Ma J, Yang Y, He X, Pan X, Wang Z, Qian Y

OncoTargets and Therapy 2020, 13:3411-3423

Published Date: 22 April 2020

Original Research

LINC01272 Promotes Migration and Invasion of Gastric Cancer Cells via EMT

Leng X, Liu G, Wang S, Song J, Zhang W, Zhang X, Rong L, Ma Y, Song F

OncoTargets and Therapy 2020, 13:3401-3410

Published Date: 22 April 2020

Original Research

miR-934 as a Prognostic Marker Facilitates Cell Proliferation and Migration of Pancreatic Tumor by Targeting PROX1

Jin Y, Weng Y, Wang Y, Lin J, Deng X, Shen B, Zhan Q, Lu X

OncoTargets and Therapy 2020, 13:3389-3399

Published Date: 22 April 2020

Original Research

Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment

Chen R, Lu X, Li Z, Sun Y, He Z, Li X

OncoTargets and Therapy 2020, 13:3375-3387

Published Date: 22 April 2020

Original Research

HBXIP Regulates Gastric Cancer Glucose Metabolism and Malignancy Through PI3K/AKT and p53 Signaling

Qiu L, Lu F, Zhang L, Wang G, Geng R, Miao Y

OncoTargets and Therapy 2020, 13:3359-3374

Published Date: 21 April 2020

Original Research

PRMT5 Promotes Aerobic Glycolysis and Invasion of Breast Cancer Cells by Regulating the LXRα/NF-κBp65 Pathway

Han X, Wei L, Wu B

OncoTargets and Therapy 2020, 13:3347-3357

Published Date: 21 April 2020

Original Research

Comprehensive Analysis of CDC27 Related to Peritoneal Metastasis by Whole Exome Sequencing in Gastric Cancer

Wu R, Li Q, Wu F, Shi C, Chen Q

OncoTargets and Therapy 2020, 13:3335-3346

Published Date: 21 April 2020

Original Research

CD47 Overexpression Is Associated with Epstein–Barr Virus Infection and Poor Prognosis in Patients with Nasopharyngeal Carcinoma

Wang ZH, Pei XF, Zhu ZQ, Lin Z, Mao YY, Xu XL, Luo YL, Zhang L, Peng PJ

OncoTargets and Therapy 2020, 13:3325-3334

Published Date: 21 April 2020

Case report

Recurrent Metastatic Penile Cancer Patient with Positive PD-L1 Expression Obtained Significant Benefit from Immunotherapy: A Case Report and Literature Review

Su X, Zhang J, Fu C, Xiao M, Wang C

OncoTargets and Therapy 2020, 13:3319-3324

Published Date: 21 April 2020

Review

Tumor Necrosis Factor Alpha-Induced Proteins in Malignant Tumors: Progress and Prospects

Guo F, Yuan Y

OncoTargets and Therapy 2020, 13:3303-3318

Published Date: 20 April 2020

Original Research

Exosomal lncRNA RAMP2-AS1 Derived from Chondrosarcoma Cells Promotes Angiogenesis Through miR-2355-5p/VEGFR2 Axis

Cheng C, Zhang Z, Cheng F, Shao Z

OncoTargets and Therapy 2020, 13:3291-3301

Published Date: 20 April 2020

Expression of Concern

Efficacy of sorafenib after liver transplantation in patients with primary hepatic carcinoma exceeding the Milan criteria: a preliminary study [Expression of concern]

Huang L, Li G, Zhu J, Li Z, Li T, Leng X

OncoTargets and Therapy 2020, 13:3289-3290

Published Date: 20 April 2020

Original Research

Chrysin Induced Cell Apoptosis and Inhibited Invasion Through Regulation of TET1 Expression in Gastric Cancer Cells

Zhong X, Liu D, Jiang Z, Li C, Chen L, Xia Y, Liu D, Yao Q, Wang D

OncoTargets and Therapy 2020, 13:3277-3287

Published Date: 20 April 2020

Original Research

Long Non-Coding RNA-NEAT1 Promotes Cell Migration and Invasion via Regulating miR-124/NF-κB Pathway in Cervical Cancer

Shen X, Zhao W, Zhang Y, Liang B

OncoTargets and Therapy 2020, 13:3265-3276

Published Date: 17 April 2020

Case report

Myeloid Blast Crisis of Chronic Myeloid Leukemia Followed by Lineage Switch to B-Lymphoblastic Leukemia: A Case Report

Liu J, Zhou Y, Yuan Q, Xiao M

OncoTargets and Therapy 2020, 13:3259-3264

Published Date: 17 April 2020

Original Research

Silencing of Long Noncoding RNA LINC00346 Inhibits the Tumorigenesis of Colorectal Cancer Through Targeting MicroRNA-148b

Li T, Wang B, Zhang L, Cui M, Sun B

OncoTargets and Therapy 2020, 13:3247-3257

Published Date: 17 April 2020

Original Research

Grainyhead-Like Genes Family May Act as Novel Biomarkers in Colon Cancer

Yuan M, Wang J, Fang F

OncoTargets and Therapy 2020, 13:3237-3245

Published Date: 17 April 2020

Original Research

Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway

Liu X, Liu C, Chen C, Sun W, Ci Y, Li Q, Song Y

OncoTargets and Therapy 2020, 13:3223-3235

Published Date: 16 April 2020

Original Research

Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic Glycolysis

Liu W, Yu X, Zhou L, Li J, Li M, Li W, Gao F

OncoTargets and Therapy 2020, 13:3209-3221

Published Date: 16 April 2020

Original Research

Bioinformatics Analysis to Reveal Potential Differentially Expressed Long Non-Coding RNAs and Genes Associated with Tumour Metastasis in Lung Adenocarcinoma

Yao X, Zhang H, Tang S, Zheng X, Jiang L

OncoTargets and Therapy 2020, 13:3197-3207

Published Date: 16 April 2020

Original Research

Long Non-Coding RNA HAND2-AS1 Inhibits Growth and Migration of Gastric Cancer Cells Through Regulating the miR-590-3p/KCNT2 Axis

Yu L, Li H, Li Z, Jia J, Wu Z, Wang M, Li F, Feng Z, Xia H, Gao G

OncoTargets and Therapy 2020, 13:3187-3196

Published Date: 16 April 2020

Original Research

PFND1 Predicts Poor Prognosis of Gastric Cancer and Promotes Cell Metastasis by Activating the Wnt/β-Catenin Pathway

Zhou C, Guo Z, Xu L, Jiang H, Sun P, Zhu X, Mu X

OncoTargets and Therapy 2020, 13:3177-3186

Published Date: 16 April 2020

Original Research

Pharmacological Inhibition of Necroptosis Promotes Human Breast Cancer Cell Proliferation and Metastasis

Shen F, Pan X, Li M, Chen Y, Jiang Y, He J

OncoTargets and Therapy 2020, 13:3165-3176

Published Date: 16 April 2020

Original Research

The lncRNA LINC01194/miR-486-5p Axis Facilitates Malignancy in Non-Small Cell Lung Cancer via Regulating CDK4

Xing Z, Zhang Z, Gao Y, Zhang X, Kong X, Zhang J, Bai H

OncoTargets and Therapy 2020, 13:3151-3163

Published Date: 15 April 2020

Original Research

PCSK1 Overexpression in Rectal Cancer Correlates with Poor Response to Preoperative Chemoradiotherapy and Prognosis

Chou CL, Chen TJ, Lin CY, Lee SW, Wang SC, Chu SS, Yang CC

OncoTargets and Therapy 2020, 13:3141-3150

Published Date: 15 April 2020

Original Research

Lamin B1 Overexpresses in Lung Adenocarcinoma and Promotes Proliferation in Lung Cancer Cells via AKT Pathway

Li W, Li X, Li X, Li M, Yang P, Wang X, Li L, Yang B

OncoTargets and Therapy 2020, 13:3129-3139

Published Date: 15 April 2020

Original Research

LncRNA OR3A4 Regulated the Growth of Osteosarcoma Cells by Modulating the miR-1207-5p/G6PD Signaling

Wang X, Chen K, Zhao Z

OncoTargets and Therapy 2020, 13:3117-3128

Published Date: 15 April 2020

Original Research

TUG1 Promoted Tumor Progression by Sponging miR-335-5p and Regulating CXCR4-Mediated Infiltration of Pro-Tumor Immunocytes in CTNNB1-Mutated Hepatoblastoma

Xie F, Zhang L, Yao Q, Shan L, Liu J, Dong N, Liang J

OncoTargets and Therapy 2020, 13:3105-3115

Published Date: 14 April 2020

Original Research

RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer

Wang P, Zhang W, Wang L, Liang W, Cai A, Gao Y, Chen L

OncoTargets and Therapy 2020, 13:3093-3103

Published Date: 14 April 2020

Review

Rationale for Lung Adenocarcinoma Prevention and Drug Development Based on Molecular Biology During Carcinogenesis

Zhang H, Guo L, Chen J

OncoTargets and Therapy 2020, 13:3085-3091

Published Date: 14 April 2020

Original Research

Rap2c as a Novel Biomarker for Predicting Poor Prognosis in Glioma

Wang X, Wang C, Xi L, Yu Z

OncoTargets and Therapy 2020, 13:3073-3083

Published Date: 14 April 2020

Original Research

RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis

Tian J, Kong E, Wang X, Xie Z, Chang CYY, Sheu JJC, Hao Q, Sun L

OncoTargets and Therapy 2020, 13:3061-3071

Published Date: 9 April 2020

Review

Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date

McCusker MG, Orkoulas-Razis D, Mehra R

OncoTargets and Therapy 2020, 13:3047-3059

Published Date: 9 April 2020

Corrigendum

Sequential Infusion of Anti-CD22 and Anti-CD19 Chimeric Antigen Receptor T Cells for a Pediatric Ph-Like B-ALL Patient That Relapsed After CART-Cell and Haplo-HSCT Therapy: A Case Report and Review of Literature [Corrigendum]

Hua J, Qian W, Wu X, Zhou L, Yu L, Chen S, Zhang J, Qiu H

OncoTargets and Therapy 2020, 13:3045-3046

Published Date: 9 April 2020

Case report

Immunotherapy Combined with Chemotherapy as a Promising Therapy for a EGFR Exon 19 Deletion with MET Amplification Patient with Non-Small-Cell Lung Cancer: A Case Report

Ni Q, Pan C, Dai S, Wang P

OncoTargets and Therapy 2020, 13:3039-3044

Published Date: 9 April 2020

Original Research

Knockdown of lncRNA PCAT6 Enhances Radiosensitivity in Triple-Negative Breast Cancer Cells by Regulating miR-185-5p/TPD52 Axis

Shi R, Wu P, Liu M, Chen B, Cong L

OncoTargets and Therapy 2020, 13:3025-3037

Published Date: 8 April 2020

Original Research

Long Noncoding RNA RMRP Suppresses the Tumorigenesis of Hepatocellular Carcinoma Through Targeting microRNA-766

Shao C, Liu G, Zhang X, Li A, Guo X

OncoTargets and Therapy 2020, 13:3013-3024

Published Date: 8 April 2020

Original Research

HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma

Guan L, Zou Q, Liu Q, Lin Y, Chen S

OncoTargets and Therapy 2020, 13:2997-3011

Published Date: 8 April 2020

Original Research

The Protective Effect of Testosterone on the Ovarian Reserve During Cyclophosphamide Treatment

Yoo M, Tanaka T, Konishi H, Tanabe A, Taniguchi K, Komura K, Hayashi M, Ohmichi M

OncoTargets and Therapy 2020, 13:2987-2995

Published Date: 8 April 2020

Original Research

Tripterine Restrains the Aggressiveness of Hepatocellular Carcinoma Cell via Regulating miRNA-532-5p/CXCL2 Axis

Jiang ZT, Han Y, Liu XY, Lv LY, Pan JH, Liu CD

OncoTargets and Therapy 2020, 13:2973-2985

Published Date: 8 April 2020

Original Research

Long Non-Coding RNA LEF1-AS1 Promotes Migration, Invasion and Metastasis of Colon Cancer Cells Through miR-30-5p/SOX9 Axis

Sun T, Liu Z, Zhang R, Ma S, Lin T, Li Y, Yang S, Zhang W, Wang Y

OncoTargets and Therapy 2020, 13:2957-2972

Published Date: 7 April 2020

Original Research

Identification of circRNA-miRNA-mRNA Networks for Exploring the Fundamental Mechanism in Lung Adenocarcinoma

Liang L, Zhang L, Zhang J, Bai S, Fu H

OncoTargets and Therapy 2020, 13:2945-2955

Published Date: 8 April 2020

Original Research

Upregulation of miR-211 Promotes Chondrosarcoma Development via Targeting Tumor Suppressor VHL

Chen C, Tian A, Zhou H, Zhang X, Liu Z, Ma X

OncoTargets and Therapy 2020, 13:2935-2943

Published Date: 5 April 2020

Original Research

Long Noncoding RNA SOCS2-AS Promotes Leukemogenesis in FLT3-ITD+ Acute Myeloid Leukemia Through miRNA-221

Zhang R, Huo C

OncoTargets and Therapy 2020, 13:2925-2934

Published Date: 5 April 2020

Original Research

MiR-499a-5p Inhibits Proliferation, Invasion, Migration, and Epithelial–Mesenchymal Transition, and Enhances Radiosensitivity of Cervical Cancer Cells via Targeting eIF4E

Gu X, Dong M, Liu Z, Yang J, Shi Y

OncoTargets and Therapy 2020, 13:2913-2924

Published Date: 5 April 2020

Corrigendum

Long Non-Coding RNA PVT1 Regulates BAMBI to Promote Tumor Progression in Non-Small Cell Lung Cancer by Sponging miR-17-5p [Corrigendum]

Wang Z, Zhang Q, Sun Y, Shao F

OncoTargets and Therapy 2020, 13:2911-2912

Published Date: 6 April 2020

Original Research

Long Non-Coding RNA FEZF1-AS1 Modulates CXCR4 to Promote Cell Proliferation, Warburg Effect and Suppress Cell Apoptosis in Osteosarcoma by Sponging miR-144

Liu J, Feng G, Li Z, Li R, Xia P

OncoTargets and Therapy 2020, 13:2899-2910

Published Date: 5 April 2020

Original Research

miR-34c Targets MET to Improve the Anti-Tumor Effect of Cisplatin on Ovarian Cancer

Yang S, Li Z, Luo R

OncoTargets and Therapy 2020, 13:2887-2897

Published Date: 5 April 2020

Original Research

CircRNA hsa_circ_0087862 Acts as an Oncogene in Non-Small Cell Lung Cancer by Targeting miR-1253/RAB3D Axis

Li L, Wan K, Xiong L, Liang S, Tou F, Guo S

OncoTargets and Therapy 2020, 13:2873-2886

Published Date: 3 April 2020

Review

A Systemic Review on the Regulatory Roles of miR-34a in Gastrointestinal Cancer

Kong J, Wang W

OncoTargets and Therapy 2020, 13:2855-2872

Published Date: 3 April 2020

Original Research

ZGRF1 Is Associated with Poor Prognosis in Triple-Negative Breast Cancer and Promotes Cancer Stemness Based on Bioinformatics

Ge W, Jiang M, Zhang F, Ma Y, Wang H, Xu Y

OncoTargets and Therapy 2020, 13:2843-2854

Published Date: 3 April 2020

Original Research

Phillygenin, a MELK Inhibitor, Inhibits Cell Survival and Epithelial–Mesenchymal Transition in Pancreatic Cancer Cells

Li H, Chen M, Yang Z, Wang Q, Wang J, Jin D, Yang X, Chen F, Zhou X, Luo K

OncoTargets and Therapy 2020, 13:2833-2842

Published Date: 3 April 2020

Original Research

Overexpression of COL24A1 in Hepatocellular Carcinoma Predicts Poor Prognosis: A Study Based on Multiple Databases, Clinical Samples and Cell Lines

Yan L, Xu F, Dai C

OncoTargets and Therapy 2020, 13:2819-2832

Published Date: 2 April 2020

Original Research

Irinotecan Induces Autophagy-Dependent Apoptosis and Positively Regulates ROS-Related JNK- and P38-MAPK Pathways in Gastric Cancer Cells

Zhu Q, Guo Y, Chen S, Fu D, Li Y, Li Z, Ni C

OncoTargets and Therapy 2020, 13:2807-2817

Published Date: 2 April 2020

Original Research

Evaluation of C5orf66-AS1 as a Potential Biomarker for Predicting Early Gastric Cancer and Its Role in Gastric Carcinogenesis

Zhou Q, Li H, Jing J, Yuan Y, Sun L

OncoTargets and Therapy 2020, 13:2795-2805

Published Date: 2 April 2020

Original Research

Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC

Ye Y, Gu J, Liu P, Wang H, Jiang L, Lei T, Yu S, Han G, Wang Z

OncoTargets and Therapy 2020, 13:2783-2793

Published Date: 2 April 2020

Original Research

Mannose Suppresses the Proliferation and Metastasis of Lung Cancer by Targeting the ERK/GSK-3β/β-Catenin/SNAIL Axis

Luo Q, Li B, Li G

OncoTargets and Therapy 2020, 13:2771-2781

Published Date: 2 April 2020

Original Research

Inhibition of EGFR Signaling and Activation of Mitochondrial Apoptosis Contribute to Tanshinone IIA-Mediated Tumor Suppression in Non-Small Cell Lung Cancer Cells

Gao F, Li M, Liu W, Li W

OncoTargets and Therapy 2020, 13:2757-2769

Published Date: 2 April 2020

Review

Matrix Stiffness and Colorectal Cancer

Liu C, Pei H, Tan F

OncoTargets and Therapy 2020, 13:2747-2755

Published Date: 1 April 2020

Original Research

Genome-Wide Microarray Analysis of circRNAs Revealed Novel Biomarkers for Glioma Treatment and Their Promoting Effect on Glioma Progression

Lyu X, Zhou L, Fan F, Dong Z

OncoTargets and Therapy 2020, 13:2739-2745

Published Date: 1 April 2020

Original Research

Up-Regulation of FSTL3, Regulated by lncRNA DSCAM-AS1/miR-122-5p Axis, Promotes Proliferation and Migration of Non-Small Cell Lung Cancer Cells

Gao L, Chen X, Wang Y, Zhang J

OncoTargets and Therapy 2020, 13:2725-2738

Published Date: 1 April 2020

Original Research

The Metastasis Potential Promoting Capacity of Cancer-Associated Fibroblasts Was Attenuated by Cisplatin via Modulating KRT8

Li X, Song Q, Guo X, Wang L, Zhang Q, Cao L, Ren Y, Wu X, Meng Z, Xu K

OncoTargets and Therapy 2020, 13:2711-2723

Published Date: 1 April 2020

Original Research

LINC02476 Promotes the Malignant Phenotype of Hepatocellular Carcinoma by Sponging miR-497 and Increasing HMGA2 Expression

Duan Y, Zhao M, Jiang M, Li Z, Ni C

OncoTargets and Therapy 2020, 13:2701-2710

Published Date: 1 April 2020

Original Research

LncRNA HOTTIP Participates in Cisplatin Resistance of Tumor Cells by Regulating miR-137 Expression in Pancreatic Cancer

Yin F, Zhang Q, Dong Z, Hu J, Ma Z

OncoTargets and Therapy 2020, 13:2689-2699

Published Date: 1 April 2020

Original Research

LncRNA FTX Contributes to the Progression of Colorectal Cancer Through Regulating miR-192-5p/EIF5A2 Axis

Zhao K, Ye Z, Li Y, Li C, Yang X, Chen Q, Xing C

OncoTargets and Therapy 2020, 13:2677-2688

Published Date: 31 March 2020

Original Research

KIF4A Promotes Clear Cell Renal Cell Carcinoma (ccRCC) Proliferation in vitro and in vivo

Yang GH, Ren ZX, Yang X, Zhang YG

OncoTargets and Therapy 2020, 13:2667-2676

Published Date: 31 March 2020

Review

Combination Strategies of Checkpoint Immunotherapy in Metastatic Breast Cancer

Liu ZB, Zhang L, Bian J, Jian J

OncoTargets and Therapy 2020, 13:2657-2666

Published Date: 31 March 2020

Original Research

Lung Cancer Cells Derived Circulating miR-21 Promotes Differentiation of Monocytes into Osteoclasts

Zhao Q, Liu C, Xie Y, Tang M, Luo G, Chen X, Tian L, Yu X

OncoTargets and Therapy 2020, 13:2643-2656

Published Date: 31 March 2020

Original Research

Overexpression of Progerin Results in Impaired Proliferation and Invasion of Non-Small Cell Lung Cancer Cells

Hu XT, Song HC, Yu H, Wu ZC, Liu XG, Chen WC

OncoTargets and Therapy 2020, 13:2629-2642

Published Date: 30 March 2020

Original Research

PCK1 Regulates Glycolysis and Tumor Progression in Clear Cell Renal Cell Carcinoma Through LDHA

Shi L, An S, Liu Y, Liu J, Wang F

OncoTargets and Therapy 2020, 13:2613-2627

Published Date: 30 March 2020

Original Research

Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial–Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9)

Wu Q, Zhao M, Huang G, Zheng Z, Chen Y, Zeng W, Lv X

OncoTargets and Therapy 2020, 13:2599-2611

Published Date: 27 March 2020

Original Research

Prognostic Value and Molecular Regulatory Mechanism of MSTO2P in Hepatocellular Carcinoma: A Comprehensive Study Based on Bioinformatics, Clinical Analysis and in vitro Validation

Yan L, Yue C, Xu Y, Jiang X, Zhang L, Wu J

OncoTargets and Therapy 2020, 13:2583-2598

Published Date: 27 March 2020

Original Research

The Long Non-Coding RNA-RoR Promotes the Tumorigenesis of Human Colorectal Cancer by Targeting miR-6833-3p Through SMC4

Li X, Chen W, Jia J, You Z, Hu C, Zhuang Y, Lin Z, Liu Y, Yang C, Xu R

OncoTargets and Therapy 2020, 13:2573-2581

Published Date: 27 March 2020

Original Research

Determination of Serum Exosomal H19 as a Noninvasive Biomarker for Breast Cancer Diagnosis

Zhong G, Wang K, Li J, Xiao S, Wei W, Liu J

OncoTargets and Therapy 2020, 13:2563-2571

Published Date: 27 March 2020

Review

Is there a CDKN2A-centric network in pancreatic ductal adenocarcinoma?

Wu C, Yang P, Liu B, Tang Y

OncoTargets and Therapy 2020, 13:2551-2562

Published Date: 27 March 2020

Original Research

miR-26a-5p Inhibit Gastric Cancer Cell Proliferation and Invasion Through Mediated Wnt5a

Li Y, Wang P, Wu LL, Yan J, Pang XY, Liu SJ

OncoTargets and Therapy 2020, 13:2537-2550

Published Date: 27 March 2020

Original Research

LncRNA LINC00665 Promotes Prostate Cancer Progression via miR-1224-5p/SND1 Axis

Chen W, Yu Z, Huang W, Yang Y, Wang F, Huang H

OncoTargets and Therapy 2020, 13:2527-2535

Published Date: 26 March 2020

Retraction

The Prognostic Value of LINC01296 in Pan-Cancers and the Molecular Regulatory Mechanism in Hepatocellular Carcinoma: A Comprehensive Study Based on Data Mining, Bioinformatics, and in vitro Validation [Retraction]

Liang C, Zhang Y, Zhang Y, Li R, Wang Z, Wei Z, Guo J

OncoTargets and Therapy 2020, 13:2525-2526

Published Date: 26 March 2020

Retraction

The Long Non-Coding RNA SBF2-AS1 Exerts Oncogenic Functions in Gastric Cancer by Targeting the miR-302b-3p/E2F Transcription Factor 3 Axis [Retraction]

Liang C, Yue C, Liang C, Ge H, Wei Z, Li G, Wu J, Huang H, Guo J

OncoTargets and Therapy 2020, 13:2523-2524

Published Date: 26 March 2020

Original Research

GRHL2 Acts as an Anti-Oncogene in Bladder Cancer by Regulating ZEB1 in Epithelial-Mesenchymal Transition (EMT) Process

Shen J, Lv X, Zhang L

OncoTargets and Therapy 2020, 13:2511-2522

Published Date: 25 March 2020

Review

MET Oncogene in Non-Small Cell Lung Cancer: Mechanism of MET Dysregulation and Agents Targeting the HGF/c-Met Axis

Liang H, Wang M

OncoTargets and Therapy 2020, 13:2491-2510

Published Date: 25 March 2020

Original Research

Long Non-Coding RNA BCAR4 Binds to miR-644a and Targets TLX1 to Promote the Progression of Bladder Cancer

Wang X, He H, Rui W, Xie X, Wang D, Zhu Y

OncoTargets and Therapy 2020, 13:2483-2490

Published Date: 24 March 2020

Original Research

Bit1 Silencing Enhances the Proliferation, Migration, and Invasion of Glioma Cells Through Activation of the IL-6/STAT3 Pathway

Wang Z, Yin M, Wang R, Liu X, Yan D

OncoTargets and Therapy 2020, 13:2469-2481

Published Date: 24 March 2020

Original Research

MicroRNA-126 Inhibit Viability of Colorectal Cancer Cell by Repressing mTOR Induced Apoptosis and Autophagy

Wei L, Chen Z, Cheng N, Li X, Chen J, Wu D, Dong M, Wu X

OncoTargets and Therapy 2020, 13:2459-2468

Published Date: 24 March 2020

Original Research

lncRNA NEAT1 Facilitates Cell Proliferation, Invasion and Migration by Regulating CBX7 and RTCB in Breast Cancer

Yan L, Zhang Z, Yin X, Li Y

OncoTargets and Therapy 2020, 13:2449-2458

Published Date: 24 March 2020

Review

The Use of Molecular Subtypes for Precision Therapy of Recurrent and Metastatic Gastrointestinal Stromal Tumor

Liu P, Tan F, Liu H, Li B, Lei T, Zhao X

OncoTargets and Therapy 2020, 13:2433-2447

Published Date: 24 March 2020

Original Research

CK19 Promotes Ovarian Cancer Development by Impacting on Wnt/β-Catenin Pathway

Lu Q, Qu H, Lou T, Liu C, Zhang Z

OncoTargets and Therapy 2020, 13:2421-2431

Published Date: 24 March 2020

Original Research

Dysregulation of SPRR3/miR-876-3p Axis Contributes to Tumorigenesis in Non-Small-Cell Lung Cancer

Li Q, Wang Y, Hu R, Yang G

OncoTargets and Therapy 2020, 13:2411-2419

Published Date: 23 March 2020

Original Research

CircRNA ZNF609 Knockdown Suppresses Cell Growth via Modulating miR-188/ELF2 Axis in Nasopharyngeal Carcinoma

Li M, Li Y, Yu M

OncoTargets and Therapy 2020, 13:2399-2409

Published Date: 23 March 2020

Original Research

Downregulation of RAGE Inhibits Cell Proliferation and Induces Apoptosis via Regulation of PI3K/AKT Pathway in Cervical Squamous Cell Carcinoma

Li R, Song Y, Zhou L, Li W, Zhu X

OncoTargets and Therapy 2020, 13:2385-2397

Published Date: 20 March 2020

Original Research

Albumin-to-Alkaline Phosphatase Ratio Associates with Good Prognosis of Hepatitis B Virus-Positive HCC Patients

Li Q, Lyu Z, Wang L, Li F, Yang Z, Ren W

OncoTargets and Therapy 2020, 13:2377-2384

Published Date: 20 March 2020

Original Research

miR-145-5p Regulates the Proliferation, Migration and Invasion in Cervical Carcinoma by Targeting KLF5

Cao H, Pan G, Tang S, Zhong N, Liu H, Zhou H, Peng Q, Zou Y

OncoTargets and Therapy 2020, 13:2369-2376

Published Date: 20 March 2020

Original Research

Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335

Yang F, Tang Z, Duan A, Yi B, Shen N, Bo Z, Yin L, Zhu B, Qiu Y, Li J

OncoTargets and Therapy 2020, 13:2357-2367

Published Date: 20 March 2020

Original Research

LncRNA FOXP4-AS1 Is Involved in Cervical Cancer Progression via Regulating miR-136-5p/CBX4 Axis

Zhao J, Yang T, Li L

OncoTargets and Therapy 2020, 13:2347-2355

Published Date: 19 March 2020

Original Research

Promotion of miR-221-5p on the Sensitivity of Gastric Cancer Cells to Cisplatin and Its Effects on Cell Proliferation and Apoptosis by Regulating DDR1

Jiang X, Jiang M, Guo S, Cai P, Wang W, Li Y

OncoTargets and Therapy 2020, 13:2333-2345

Published Date: 18 March 2020

Original Research

Knockdown of lncRNA TUG1 Enhances Radiosensitivity of Prostate Cancer via the TUG1/miR-139-5p/SMC1A Axis

Xiu D, Liu L, Cheng M, Sun X, Ma X

OncoTargets and Therapy 2020, 13:2319-2331

Published Date: 17 March 2020

Case report

Sequential Infusion of Anti-CD22 and Anti-CD19 Chimeric Antigen Receptor T Cells for a Pediatric Ph-Like B-ALL Patient That Relapsed After CART-Cell and Haplo-HSCT Therapy: A Case Report and Review of Literature

Hua J, Qian W, Wu X, Zhou L, Yu L, Chen S, Zhang J, Qiu H

OncoTargets and Therapy 2020, 13:2311-2317

Published Date: 17 March 2020

Original Research

ANGPTL4 Promotes the Proliferation of Papillary Thyroid Cancer via AKT Pathway

Yang L, Wang Y, Sun R, Zhang Y, Fu Y, Zheng Z, Ji Z, Zhao D

OncoTargets and Therapy 2020, 13:2299-2309

Published Date: 17 March 2020

Review

Contemporary Multidisciplinary Management of Sinonasal Mucosal Melanoma

Na'ara S, Mukherjee A, Billan S, Gil Z

OncoTargets and Therapy 2020, 13:2289-2298

Published Date: 16 March 2020

Original Research

Polyphyllin VI Induces Apoptosis and Autophagy via Reactive Oxygen Species Mediated JNK and P38 Activation in Glioma

Liu W, Chai Y, Hu L, Wang J, Pan X, Yuan H, Zhao Z, Song Y, Zhang Y

OncoTargets and Therapy 2020, 13:2275-2288

Published Date: 13 March 2020

Original Research

Long Non-Coding RNA ASB16-AS1 Functions as a miR-760 Sponge to Facilitate the Malignant Phenotype of Osteosarcoma by Increasing HDGF Expression

Yin R, Liu J, Zhao D, Wang F

OncoTargets and Therapy 2020, 13:2261-2274

Published Date: 13 March 2020

Original Research

Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2

Yang Y, Liu X, Cheng L, Li L, Wei Z, Wang Z, Han G, Wan X, Wang Z, Zhang J, Chen C

OncoTargets and Therapy 2020, 13:2247-2260

Published Date: 13 March 2020

Original Research

MiR-154-5p Suppresses Cell Invasion and Migration Through Inhibiting KIF14 in Nasopharyngeal Carcinoma

Chen J, Ma C, Zhang Y, Pei S, Du M, Zhang Y, Qian L, Wang J, Yin L, He X

OncoTargets and Therapy 2020, 13:2235-2246

Published Date: 13 March 2020

Original Research

Silencing of Long Non-Coding RNA-HCG18 Inhibits the Tumorigenesis of Gastric Cancer Through Blocking PI3K/Akt Pathway

Ma F, An K, Li Y

OncoTargets and Therapy 2020, 13:2225-2234

Published Date: 18 March 2020

Original Research

B7-H3 Regulates Glioma Growth and Cell Invasion Through a JAK2/STAT3/Slug-Dependent Signaling Pathway

Zhong C, Tao B, Chen Y, Guo Z, Yang X, Peng L, Xia X, Chen L

OncoTargets and Therapy 2020, 13:2215-2224

Published Date: 12 March 2020

Original Research

Novel Alternatively Spliced Variants of Smad4 Expressed in TGF-β-Induced EMT Regulating Proliferation and Migration of A549 Cells

Wan R, Xu X, Ma L, Chen Y, Tang L, Feng J

OncoTargets and Therapy 2020, 13:2203-2213

Published Date: 11 March 2020

Original Research

RAB43 Promotes Gastric Cancer Cell Proliferation and Metastasis via Regulating the PI3K/AKT Signaling Pathway

Huang Z, Liang H, Chen L

OncoTargets and Therapy 2020, 13:2193-2202

Published Date: 11 March 2020

Review

ERα, A Key Target for Cancer Therapy: A Review

Liu Y, Ma H, Yao J

OncoTargets and Therapy 2020, 13:2183-2191

Published Date: 11 March 2020

Original Research

Up-Regulation of Hsa_circ_0008792 Inhibits Osteosarcoma Cell Invasion and Migration and Promotes Apoptosis by Regulating Hsa-miR-711/ZFP1

Chen L, Shan Y, Zhang H, Wang H, Chen Y

OncoTargets and Therapy 2020, 13:2173-2181

Published Date: 11 March 2020

Original Research

HOXD9 Activates the TGF-β/Smad Signaling Pathway to Promote Gastric Cancer

Xiong R, Yin T, Gao J, Yuan Y

OncoTargets and Therapy 2020, 13:2163-2172

Published Date: 10 March 2020

Original Research

MiR-483 Targeted SOX3 to Suppress Glioma Cell Migration, Invasion and Promote Cell Apoptosis

Lu S, Yu Z, Zhang X, Sui L

OncoTargets and Therapy 2020, 13:2153-2161

Published Date: 9 March 2020

Original Research

5-HT7 Receptor Contributes to Proliferation, Migration and Invasion in NSCLC Cells

Du X, Wang T, Wang Z, Wu X, Gu Y, Huang Q, Wang J, Xie J

OncoTargets and Therapy 2020, 13:2139-2151

Published Date: 9 March 2020

Original Research

HANR Enhances Autophagy-Associated Sorafenib Resistance Through miR-29b/ATG9A Axis in Hepatocellular Carcinoma

Shi Y, Yang X, Xue X, Sun D, Cai P, Song Q, Zhang B, Qin L

OncoTargets and Therapy 2020, 13:2127-2137

Published Date: 9 March 2020

Retraction

Simultaneous Overexpression of miR-126 and miR-34a Induces a Superior Antitumor Efficacy in Pancreatic Adenocarcinoma [Retraction]

Feng SD, Mao ZM, Liu CY, Nie YS, Sun B, Guo MG, Su CQ

OncoTargets and Therapy 2020, 13:2125-2126

Published Date: 9 March 2020

Original Research

Down-regulation of lncRNA LINC00152 Suppresses Gastric Cancer Cell Migration and Invasion Through Inhibition of the ERK/MAPK Signaling Pathway

Shi Y, Sun H

OncoTargets and Therapy 2020, 13:2115-2124

Published Date: 9 March 2020

Original Research

UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1

Xing T, Chen P, Wu J, Gao L, Yang W, Cheng Y, Tong L

OncoTargets and Therapy 2020, 13:2103-2114

Published Date: 9 March 2020

Original Research

Prognostic Nomogram for Patients with Radical Surgery for Non-Metastatic Colorectal Cancer Incorporating Hematological Biomarkers and Clinical Characteristics

Long P, Zang Y, Wang H, Liang X, Xie X, Han Z, Lin D, Wang Z, Huang S, Chen C

OncoTargets and Therapy 2020, 13:2093-2102

Published Date: 9 March 2020

Review

Biological Roles and Mechanisms of Circular RNA in Human Cancers

Tang Q, Hann SS

OncoTargets and Therapy 2020, 13:2067-2092

Published Date: 9 March 2020

Original Research

Simvastatin Inhibits the Malignant Behaviors of Gastric Cancer Cells by Simultaneously Suppressing YAP and β-Catenin Signaling

Liu Q, Xia H, Zhou S, Tang Q, Zhou J, Ren M, Bi F

OncoTargets and Therapy 2020, 13:2057-2066

Published Date: 9 March 2020

Original Research

EMP1 Promotes the Proliferation and Invasion of Ovarian Cancer Cells Through Activating the MAPK Pathway

Liu Y, Ding Y, Nie Y, Yang M

OncoTargets and Therapy 2020, 13:2047-2055

Published Date: 9 March 2020

Original Research

Long Non-Coding RNA DLEU1 Up-Regulates BIRC6 Expression by Competitively Sponging miR-381-3p to Promote Cisplatin Resistance in Nasopharyngeal Carcinoma

Li H, Huang J, Yu S, Lou Z

OncoTargets and Therapy 2020, 13:2037-2045

Published Date: 9 March 2020

Original Research

Potential Influences of RNF6 on Prognosis and Metastasis of Colorectal Cancer: A Clinical Analysis

Zhu H, Wang C

OncoTargets and Therapy 2020, 13:2031-2036

Published Date: 9 March 2020

Original Research

Exosomal MicroRNAs as Liquid Biopsy Biomarkers in Hepatocellular Carcinoma

Wang S, Yang Y, Sun L, Qiao G, Song Y, Liu B

OncoTargets and Therapy 2020, 13:2021-2030

Published Date: 9 March 2020

Original Research

Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells

Gu L, Li Q, Liu H, Lu X, Zhu M

OncoTargets and Therapy 2020, 13:2007-2019

Published Date: 6 March 2020

Original Research

TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition

Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, Tang X, Chen Z

OncoTargets and Therapy 2020, 13:1993-2006

Published Date: 6 March 2020

Original Research

Long Noncoding RNA LINC00460 Promotes Hepatocellular Carcinoma Progression via Regulation of miR-342-3p/AGR2 Axis

Yang J, Li K, Chen J, Hu X, Wang H, Zhu X

OncoTargets and Therapy 2020, 13:1979-1991

Published Date: 6 March 2020

Original Research

HIPK3 Promotes Growth and Metastasis of Esophageal Squamous Cell Carcinoma via Regulation of miR-599/c-MYC Axis

Ba Y, Liu Y, Li C, Zhu Y, Xing W

OncoTargets and Therapy 2020, 13:1967-1978

Published Date: 6 March 2020

Original Research

Omega-3PUFA Attenuates MNU-Induced Colorectal Cancer in Rats by Blocking PI3K/AKT/Bcl-2 Signaling

Huang Z, Liu CA, Cai PZ, Xu FP, Zhu WJ, Wang WW, Jiang HP

OncoTargets and Therapy 2020, 13:1953-1965

Published Date: 5 March 2020

Original Research

Circular RNA 0060745, a Novel circRNA, Promotes Colorectal Cancer Cell Proliferation and Metastasis Through miR-4736 Sponging

Wang X, Ren Y, Ma S, Wang S

OncoTargets and Therapy 2020, 13:1941-1951

Published Date: 5 March 2020

Original Research

Circulating Tumor Cells as a Screening and Diagnostic Marker for Early-Stage Non-Small Cell Lung Cancer

Duan GC, Zhang XP, Wang HE, Wang ZK, Zhang H, Yu L, Xue WF, Xin ZF, Hu ZH, Zhao QT

OncoTargets and Therapy 2020, 13:1931-1939

Published Date: 4 March 2020

Original Research

Circular RNA hsa_circ_0068033 Acts as a Diagnostic Biomarker and Suppresses the Progression of Breast Cancer Through Sponging miR-659

Yuan P, Lei L, Dong S, Liu D

OncoTargets and Therapy 2020, 13:1921-1929

Published Date: 4 March 2020

Original Research

Berberine Reverses Doxorubicin Resistance by Inhibiting Autophagy Through the PTEN/Akt/mTOR Signaling Pathway in Breast Cancer

Wang Y, Liu Y, Du X, Ma H, Yao J

OncoTargets and Therapy 2020, 13:1909-1919

Published Date: 4 March 2020

Erratum

SMAGP a Novel Biomarker of Cervical Cancer Development and Progression [Erratum]

Jia Y, Li H, Liu G, Song F

OncoTargets and Therapy 2020, 13:1907-1908

Published Date: 4 March 2020

Original Research

Adequate Lymph Node Assessments and Investigation of Gut Microorganisms and Microbial Metabolites in Colorectal Cancer

Han S, Wu W, Da M, Xu J, Zhuang J, Zhang L, Zhang X, Yang X

OncoTargets and Therapy 2020, 13:1893-1906

Published Date: 4 March 2020

Original Research

Serum Platelet-Derived Growth Factor Is Significantly Lower in Patients with Lung Cancer and Continued to Decrease After Platinum-Based Chemotherapy

Ma R, Yang Q, Cao S, Liu S, Cao H, Xu H, Wu J, Feng J

OncoTargets and Therapy 2020, 13:1883-1892

Published Date: 4 March 2020

Original Research

The Role of β-Arrestin1 in Esophageal Squamous Cell Carcinoma

Tan Z, Li B, Dong X, Liu W, Liu S

OncoTargets and Therapy 2020, 13:1873-1881

Published Date: 3 March 2020

Corrigendum

Effects of Adenosine on Apoptosis of Ovarian Cancer A2780 Cells via ROS and Caspase Pathways [Corrigendum]

Xia B, Wang J

OncoTargets and Therapy 2020, 13:1871-1872

Published Date: 3 March 2020

Original Research

MicroRNA Profile Identifies miR-6165 Could Suppress Gastric Cancer Migration and Invasion by Targeting STRN4

Wang Z, Li Y, Cao J, Zhang W, Wang Q, Zhang Z, Gao Z, Ye Y, Jiang K, Wang S

OncoTargets and Therapy 2020, 13:1859-1869

Published Date: 3 March 2020

Original Research

Elevated Expression of miR-629 Predicts a Poor Prognosis and Promotes Cell Proliferation, Migration, and Invasion of Osteosarcoma

Li X, Li N, Niu Q, Zhu H, Wang Z, Hou Q

OncoTargets and Therapy 2020, 13:1851-1857

Published Date: 2 March 2020

Case report

An EGFR-Amplified Cervical Squamous Cell Carcinoma Patient with Pulmonary Metastasis Benefits from Afatinib: A Case Report

Chen Q, Huang Y, Shao L, Han-Zhang H, Yang F, Wang Y, Liu J, Gan J

OncoTargets and Therapy 2020, 13:1845-1849

Published Date: 28 February 2020

Original Research

LncRNA LINC01140 Inhibits Glioma Cell Migration and Invasion via Modulation of miR-199a-3p/ZHX1 Axis

Xin Y, Zhang W, Mao C, Li J, Liu X, Zhao J, Xue J, Li J, Ren Y

OncoTargets and Therapy 2020, 13:1833-1844

Published Date: 28 February 2020

Original Research

PVT1 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer via Regulating miR-148/RAB34 Signal Axis

Xi Y, Shen W, Jin C, Wang L, Yu B

OncoTargets and Therapy 2020, 13:1819-1832

Published Date: 28 February 2020

Original Research

Variants of MIR137HG Genes are Associated with Liver Cancer Risk in Chinese Li Population

Wang C, Zhuang X, Xu J, Dai Z, Wu W, Zhang C, Lin S, Chen S, Lin H, Tang W

OncoTargets and Therapy 2020, 13:1809-1818

Published Date: 28 February 2020

Review

A Review of Research Progress in Multidrug-Resistance Mechanisms in Gastric Cancer

Ruan T, Liu W, Tao K, Wu C

OncoTargets and Therapy 2020, 13:1797-1807

Published Date: 28 February 2020

Review

Phosphoglycerate Mutase 1: Its Glycolytic and Non-Glycolytic Roles in Tumor Malignant Behaviors and Potential Therapeutic Significance

Li N, Liu X

OncoTargets and Therapy 2020, 13:1787-1795

Published Date: 27 February 2020

Original Research

Hsa_circ_103973 Acts as a Sponge of miR-335 to Promote Cervical Cancer Progression

Zhu Y, Jiang X, Zhang S, Wang L, Zhou Q, Jiang J

OncoTargets and Therapy 2020, 13:1777-1786

Published Date: 28 February 2020

Original Research

Gluconokinase IDNK Promotes Cell Proliferation and Inhibits Apoptosis in Hepatocellular Carcinoma

Wu XM, Jin C, Gu YL, Chen WQ, Zhu MQ, Zhang S, Zhang Z

OncoTargets and Therapy 2020, 13:1767-1776

Published Date: 26 February 2020

Original Research

High Soluble Programmed Death-Ligand 1 Predicts Poor Prognosis in Patients with Nasopharyngeal Carcinoma

Lu T, Chen Y, Li J, Guo Q, Lin W, Zheng Y, Su Y, Zong J, Lin S, Ye Y, Pan J

OncoTargets and Therapy 2020, 13:1757-1765

Published Date: 26 February 2020

Case report

Pathological Complete Response After a Single Dose of Anti-PD-1 Therapy in Combination with Chemotherapy as a First-Line Setting in an Unresectable Locally Advanced Gastric Cancer with PD-L1 Positive and Microsatellite Instability

Jin H, Li P, Mao C, Zhu K, Chen H, Gao Y, Yu J

OncoTargets and Therapy 2020, 13:1751-1756

Published Date: 26 February 2020

Original Research

SRPX2 Promotes Cell Proliferation and Invasion in Osteosarcoma Through Regulating Hippo Signaling Pathway

Wu Z, Wang C, Chen Y, Sun Z, Yan W

OncoTargets and Therapy 2020, 13:1737-1749

Published Date: 26 February 2020

Original Research

Circular RNA circ_0001105 Inhibits Progression and Metastasis of Osteosarcoma by Sponging miR-766 and Activating YTHDF2 Expression

Yang J, Han Q, Li C, Yang H, Chen X, Wang X

OncoTargets and Therapy 2020, 13:1723-1736

Published Date: 26 February 2020

Short Report

Efficacy and Safety of Apatinib in the Treatment of Postoperative Recurrence of Fibrosarcoma

Ma H, Fang J, Wang T, Wang D, Wang L, Wang C, Tang L, Tang Y, Lu S, Wang Y, Chen X

OncoTargets and Therapy 2020, 13:1717-1721

Published Date: 25 February 2020

Original Research

Serum miR-191 and miR-425 as Diagnostic and Prognostic Markers of Advanced Gastric Cancer Can Predict the Sensitivity of FOLFOX Chemotherapy Regimen

Bie LY, Li N, Deng WY, Lu XY, Guo P, Luo SX

OncoTargets and Therapy 2020, 13:1705-1715

Published Date: 25 February 2020

Original Research

Long Noncoding RNA RGMB-AS1 Acts as a microRNA-574 Sponge Thereby Enhancing the Aggressiveness of Gastric Cancer via HDAC4 Upregulation

Wang X, Chen X, Tian Y, Jiang D, Song Y

OncoTargets and Therapy 2020, 13:1691-1704

Published Date: 24 February 2020

Original Research

LncRNA SNHG7 Functions as an Oncogene in Cervical Cancer by Sponging miR-485-5p to Modulate JUND Expression

Zhao D, Zhang H, Long J, Li M

OncoTargets and Therapy 2020, 13:1677-1689

Published Date: 25 February 2020

Original Research

Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway

BommaReddy RR, Patel R, Smalley T, Acevedo-Duncan M

OncoTargets and Therapy 2020, 13:1661-1676

Published Date: 24 February 2020

Original Research

Downregulation of miR-486-5p Enhances the Anti-Tumor Effect of 5-Fluorouracil on Pancreatic Cancer Cells

Wang W, Liu B, Sun S, Lan L, Chen Y, Han S, Li X, Li Z

OncoTargets and Therapy 2020, 13:1649-1659

Published Date: 24 February 2020

Original Research

Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells

Yuan Q, Yu H, Chen J, Song X, Sun L

OncoTargets and Therapy 2020, 13:1637-1647

Published Date: 21 February 2020

Original Research

FOXC2 Promotes Oxaliplatin Resistance by Inducing Epithelial-Mesenchymal Transition via MAPK/ERK Signaling in Colorectal Cancer

Chen Y, Deng G, Fu Y, Han Y, Guo C, Yin L, Cai C, Shen H, Wu S, Zeng S

OncoTargets and Therapy 2020, 13:1625-1635

Published Date: 21 February 2020

Original Research

circHIPK3 Promotes Cell Proliferation and Migration of Gastric Cancer by Sponging miR-107 and Regulating BDNF Expression

Wei J, Xu H, Wei W, Wang Z, Zhang Q, De W, Shu Y

OncoTargets and Therapy 2020, 13:1613-1624

Published Date: 21 February 2020

Original Research

Progression of Thyroid Carcinoma Is Promoted by the m6A Methyltransferase METTL3 Through Regulating m6A Methylation on TCF1

Wang K, Jiang L, Zhang Y, Chen C

OncoTargets and Therapy 2020, 13:1605-1612

Published Date: 21 February 2020

Original Research

miR-26b-5p Inhibits the Proliferation, Migration and Invasion of Human Papillary Thyroid Cancer in a β-Catenin-Dependent Manner

Zhou A, Pan H, Sun D, Xu H, Zhang C, Chen X, Li L, Wang T

OncoTargets and Therapy 2020, 13:1593-1603

Published Date: 21 February 2020

Original Research

Significant Contribution of DNA Repair Human 8-Oxoguanine DNA N-Glycosylase 1 Genotypes to Renal Cell Carcinoma

Chang WS, Shen TC, Liao JM, Tsai YT, Hsia TC, Wu HC, Tsai CW, Bau DT

OncoTargets and Therapy 2020, 13:1583-1591

Published Date: 20 February 2020

Original Research

Circ_0058124 Upregulates MAPK1 Expression to Promote Proliferation, Metastasis and Metabolic Abilities in Thyroid Cancer Through Sponging miR-940

Sun D, Chen L, Lv H, Gao Y, Liu X, Zhang X

OncoTargets and Therapy 2020, 13:1569-1581

Published Date: 19 February 2020

Original Research

Safety and Efficacy of Chemotherapy Combined with Anlotinib Plus Anlotinib Maintenance in Chinese Patients with Advanced/Metastatic Soft Tissue Sarcoma

Wang H, Chu J, Zhang P, Wang J, Yan Z, Yao S, Yao Z, Liu Y

OncoTargets and Therapy 2020, 13:1561-1568

Published Date: 19 February 2020

Case report

ALK Rearrangement Adenocarcinoma with Histological Transformation to Squamous Cell Carcinoma Resistant to Alectinib and Ceritinib

Kaiho T, Nakajima T, Iwasawa S, Yonemori Y, Yoshino I

OncoTargets and Therapy 2020, 13:1557-1560

Published Date: 19 February 2020

Original Research

Knockdown of FOXO6 Inhibits Glycolysis and Reduces Cell Resistance to Paclitaxel in HCC Cells via PI3K/Akt Signaling Pathway

Yu X, Gao X, Mao X, Shi Z, Zhu B, Xie L, Di S, Jin L

OncoTargets and Therapy 2020, 13:1545-1556

Published Date: 19 February 2020

Original Research

The lncRNA NORAD/miR-520a-3p Facilitates Malignancy in Non-Small Cell Lung Cancer via PI3k/Akt/mTOR Signaling Pathway

Wan Y, Yao Z, Chen W, Li D

OncoTargets and Therapy 2020, 13:1533-1544

Published Date: 19 February 2020

Original Research

A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma

Sun Y, Niu X, Wang G, Qiao X, Chen L, Zhong M

OncoTargets and Therapy 2020, 13:1519-1531

Published Date: 19 February 2020

Original Research

HNF1A-AS1 Regulates Cell Migration, Invasion and Glycolysis via Modulating miR-124/MYO6 in Colorectal Cancer Cells

Guo X, Zhang Y, Liu L, Yang W, Zhang Q

OncoTargets and Therapy 2020, 13:1507-1518

Published Date: 18 February 2020

Original Research

Activated Hepatic Stellate Cells (HSCs) Exert Immunosuppressive Effects in Hepatocellular Carcinoma by Producing Complement C3

Xu Y, Huang Y, Xu W, Zheng X, Yi X, Huang L, Wang Y, Wu K

OncoTargets and Therapy 2020, 13:1497-1505

Published Date: 18 February 2020

Original Research

DEP Domain-Containing Protein 1B (DEPDC1B) Promotes Migration and Invasion in Pancreatic Cancer Through the Rac1/PAK1-LIMK1-Cofilin1 Signaling Pathway

Zhang S, Shi W, Hu W, Ma D, Yan D, Yu K, Zhang G, Cao Y, Wu J, Jiang C, Wang Z

OncoTargets and Therapy 2020, 13:1481-1496

Published Date: 18 February 2020

Original Research

Downregulation of USP34 Inhibits the Growth and Migration of Pancreatic Cancer Cells via Inhibiting the PRR11

Lin C, Xia J, Gu Z, Meng Y, Gao D, Wei S

OncoTargets and Therapy 2020, 13:1471-1480

Published Date: 18 February 2020

Original Research

FTO Facilitates Lung Adenocarcinoma Cell Progression by Activating Cell Migration Through mRNA Demethylation

Ding Y, Qi N, Wang K, Huang Y, Liao J, Wang H, Tan A, Liu L, Zhang Z, Li J, Kong J, Qin S, Jiang Y

OncoTargets and Therapy 2020, 13:1461-1470

Published Date: 18 February 2020

Original Research

DUB3 Facilitates Growth and Inhibits Apoptosis Through Enhancing Expression of EZH2 in Oral Squamous Cell Carcinoma

Luo F, Zhou Z, Cai J, Du W

OncoTargets and Therapy 2020, 13:1447-1460

Published Date: 18 February 2020

Original Research

lncRNA CCAT2 Enhanced Resistance of Glioma Cells Against Chemodrugs by Disturbing the Normal Function of miR-424

Ding J, Zhang L, Chen S, Cao H, Xu C, Wang X

OncoTargets and Therapy 2020, 13:1431-1445

Published Date: 17 February 2020

Original Research

Embelin Promotes Oncolytic Vaccinia Virus-Mediated Antitumor Immunity Through Disruption of IL-6/STAT3 Signaling in Lymphoma

Wang P, Wu Y, Yang C, Zhao G, Liu Y, Cheng G, Wang S

OncoTargets and Therapy 2020, 13:1421-1429

Published Date: 17 February 2020

Original Research

In vitro Transport Ability of ABCC2 (G1249A) Polymorphic Variant Towards Anticancer Drugs

Lian G, Yuan J, Gao Y

OncoTargets and Therapy 2020, 13:1413-1419

Published Date: 17 February 2020

Review

The Research Progress on the Prognostic Value of the Common Hematological Parameters in Peripheral Venous Blood in Breast Cancer

Chen L, Kong X, Yan C, Fang Y, Wang J

OncoTargets and Therapy 2020, 13:1397-1412

Published Date: 14 February 2020

Original Research

EFEMP2 Suppresses the Invasion of Lung Cancer Cells by Inhibiting Epithelial-Mesenchymal Transition (EMT) and Down-Regulating MMPs

Song L, Li XX, Liu XY, Wang Z, Yu Y, Shi M, Jiang B, He XP

OncoTargets and Therapy 2020, 13:1375-1396

Published Date: 14 February 2020

Original Research

Exosomal Long Non-Coding RNA CEBPA-AS1 Inhibits Tumor Apoptosis and Functions as a Non-Invasive Biomarker for Diagnosis of Gastric Cancer

Piao H, Guo S, Wang Y, Zhang J

OncoTargets and Therapy 2020, 13:1365-1374

Published Date: 14 February 2020

Original Research

P53 Mutant p53N236S Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway

Liu Q, Yu B, Tian Y, Dan J, Luo Y, Wu X

OncoTargets and Therapy 2020, 13:1355-1363

Published Date: 14 February 2020

Original Research

lncRNA MALAT1 modulates oxaliplatin resistance of gastric cancer via sponging miR-22-3p

Zhang Z, Li M, Zhang Z

OncoTargets and Therapy 2020, 13:1343-1354

Published Date: 13 February 2020

Original Research

Lentivirus-Mediated VEGF Knockdown Suppresses Gastric Cancer Cell Proliferation and Tumor Growth in vitro and in vivo

Park JH, Seo JH, Jeon HY, Seo SM, Lee HK, Park JI, Kim JY, Choi YK

OncoTargets and Therapy 2020, 13:1331-1341

Published Date: 13 February 2020

Original Research

DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway

Luo J, Luo X, Liu X, Fang Z, Xu J, Li L

OncoTargets and Therapy 2020, 13:1321-1330

Published Date: 13 February 2020

Original Research

Plasma Exosomal miR-146b-5p and miR-222-3p are Potential Biomarkers for Lymph Node Metastasis in Papillary Thyroid Carcinomas

Jiang K, Li G, Chen W, Song L, Wei T, Li Z, Gong R, Lei J, Shi H, Zhu J

OncoTargets and Therapy 2020, 13:1311-1319

Published Date: 13 February 2020

Original Research

KLF16 Affects the MYC Signature and Tumor Growth in Prostate Cancer

Zhang J, Yu W, Wang X, Hu B, Wu D, Shi G

OncoTargets and Therapy 2020, 13:1303-1310

Published Date: 13 February 2020

Original Research

LncRNA TUG1 Regulates Cell Viability and Death by Regulating miR-193a-5p/Rab10 Axis in Acute Myeloid Leukemia

Li Q, Wang J

OncoTargets and Therapy 2020, 13:1289-1301

Published Date: 13 February 2020

Original Research

Long Noncoding RNA X-Inactive Specific Transcript Facilitates Cellular Functions in Melanoma via miR-139-5p/ROCK1 Pathway

Tian K, Sun D, Chen M, Yang Y, Wang F, Guo T, Shi Z

OncoTargets and Therapy 2020, 13:1277-1287

Published Date: 12 February 2020

Original Research

γ-Catenin Overexpression in AML Patients May Promote Tumor Cell Survival via Activation of the Wnt/β-Catenin Axis

Qian J, Huang X, Zhang Y, Ye X, Qian W

OncoTargets and Therapy 2020, 13:1265-1276

Published Date: 12 February 2020

Original Research

Prognostic Values of LDH and CRP in Cervical Cancer

Wang H, Wang MS, Zhou YH, Shi JP, Wang WJ

OncoTargets and Therapy 2020, 13:1255-1263

Published Date: 11 February 2020

Original Research

MicroRNA-1246 Promotes Melanoma Progression Through Targeting FOXA2

Yu Y, Yu F, Sun P

OncoTargets and Therapy 2020, 13:1245-1253

Published Date: 11 February 2020

Original Research

Upregulation of Cullin 4B Promotes Gastric Cancer and Predicts Poor Prognosis

Wu P, Hu H, Li J, Gong W

OncoTargets and Therapy 2020, 13:1235-1243

Published Date: 11 February 2020

Original Research

Expression and Prognostic Value of Id-4 in Patients with Esophageal Squamous Cell Carcinoma

Wang X, Lu Q, Fei X, Zhao Y, Shi B, Li C, Chen H

OncoTargets and Therapy 2020, 13:1225-1234

Published Date: 12 February 2020

Original Research

Transcriptomics Analysis of the Tumor-Inhibitory Pathways of 6-Thioguanine in MCF-7 Cells via Silencing DNMT1 Activity

Li H, An X, Zhang D, Li Q, Zhang N, Yu H, Li Z

OncoTargets and Therapy 2020, 13:1211-1223

Published Date: 11 February 2020

Original Research

miR-4999-5p Predicts Colorectal Cancer Survival Outcome and Reprograms Glucose Metabolism by Targeting PRKAA2

Zhang Q, Hong Z, Zhu J, Zeng C, Tang Z, Wang W, Huang H

OncoTargets and Therapy 2020, 13:1199-1210

Published Date: 11 February 2020

Original Research

Knockdown of HMGB1 Suppresses Hypoxia-Induced Mitochondrial Biogenesis in Pancreatic Cancer Cells

Yang L, Ye F, Zeng L, Li Y, Chai W

OncoTargets and Therapy 2020, 13:1187-1198

Published Date: 12 February 2020

Corrigendum

Partial Stereotactic Ablative Boost Radiotherapy in Bulky Non-Small Cell Lung Cancer: A Retrospective Study [Corrigendum]

Bai Y, Gao XS, Qin SB, Chen JY, Su MM, Liu Q, Qin XB, Ma MW, Zhao B, Gu XB, Xie M, Cui M, Qi X, Li XY

OncoTargets and Therapy 2020, 13:1185-1186

Published Date: 11 February 2020

Case report

Management of Ewing Sarcoma Family of Tumors: A Short Description of a Rare Primitive Uterine pPNET and Literature Review

Pisconti S, Della Vittoria Scarpati G, Buonerba C, Messinese S, Carella R, Di Marzo M, Di Lorenzo G, Lazzari G, Perri F, Solla R

OncoTargets and Therapy 2020, 13:1179-1184

Published Date: 14 February 2020

Case report

Effective Treatment with Cabozantinib in an Advanced Non-Small-Cell Lung Cancer Patient Harboring a CD74-ROS1 Fusion: A Case Report

Wang G, Gao J, Lv J, Chen X, Wu J, Wang R, Jiang J

OncoTargets and Therapy 2020, 13:1171-1177

Published Date: 11 February 2020

Original Research

LncRNA PCAT6 Accelerates the Progression and Chemoresistance of Cervical Cancer Through Up-Regulating ZEB1 by Sponging miR-543

Ma Z, Gu G, Pan W, Chen X

OncoTargets and Therapy 2020, 13:1159-1170

Published Date: 7 February 2020

Original Research

LncRNA DANCR Promotes Sorafenib Resistance via Activation of IL-6/STAT3 Signaling in Hepatocellular Carcinoma Cells

Liu Y, Chen L, Yuan H, Guo S, Wu G

OncoTargets and Therapy 2020, 13:1145-1157

Published Date: 5 February 2020

Original Research

IFI30 Is a Novel Immune-Related Target with Predicting Value of Prognosis and Treatment Response in Glioblastoma

Zhu C, Chen X, Guan G, Zou C, Guo Q, Cheng P, Cheng W, Wu A

OncoTargets and Therapy 2020, 13:1129-1143

Published Date: 5 February 2020

Original Research

Inhibition of cyclinB1 Suppressed the Proliferation, Invasion, and Epithelial Mesenchymal Transition of Hepatocellular Carcinoma Cells and Enhanced the Sensitivity to TRAIL-Induced Apoptosis

Lv S, Ning H, Li Y, Wang J, Jia Q, Wen H

OncoTargets and Therapy 2020, 13:1119-1128

Published Date: 5 February 2020

Original Research

Long Non-Coding RNA HULC Promotes Cervical Cancer Cell Proliferation, Migration and Invasion via miR-218/TPD52 Axis

Lu W, Wan X, Tao L, Wan J

OncoTargets and Therapy 2020, 13:1109-1118

Published Date: 5 February 2020

Original Research

GAS2 Promotes Cell Proliferation and Invasion and Suppresses Apoptosis in Pediatric T-Cell Acute Lymphoblastic Leukemia and Activates Wnt/β-Catenin Pathway

Kong Y, Zhao S, Tian H, Hai Y

OncoTargets and Therapy 2020, 13:1099-1108

Published Date: 5 February 2020

Original Research

Identification of Novel lncRNA Markers in Glioblastoma Multiforme and Their Clinical Significance: A Study Based on Multiple Sequencing Data

Li Y, Guo D

OncoTargets and Therapy 2020, 13:1087-1098

Published Date: 4 February 2020

Original Research

Long Non-Coding RNA PART1 Exerts Tumor Suppressive Functions in Glioma via Sponging miR-190a-3p and Inactivation of PTEN/AKT Pathway

Jin Z, Piao L, Sun G, Lv C, Jing Y, Jin R

OncoTargets and Therapy 2020, 13:1073-1086

Published Date: 4 February 2020

Original Research

Expression and Clinical Significance of ERCC1 and XPF in Human Hepatocellular Carcinoma

Liao X, Li Y, Li H, Huang W, Wang H, Xie W

OncoTargets and Therapy 2020, 13:1059-1072

Published Date: 4 February 2020

Original Research

Bioinformatics Analysis and RNA-Sequencing of SCAMP3 Expression and Correlated Gene Regulation in Hepatocellular Carcinoma

Han S, Feng Z, Liu R, Ye J, Cheng W, Bao J

OncoTargets and Therapy 2020, 13:1047-1057

Published Date: 4 February 2020

Original Research

miR-873-5p Inhibits Cell Migration and Invasion of Papillary Thyroid Cancer via Regulation of CXCL16

Wang Z, Liu W, Wang C, Ai Z

OncoTargets and Therapy 2020, 13:1037-1046

Published Date: 4 February 2020

Original Research

Foretinib Inhibits Cancer Stemness and Gastric Cancer Cell Proliferation by Decreasing CD44 and c-MET Signaling

Sohn SH, Kim B, Sul HJ, Choi BY, Kim HS, Zang DY

OncoTargets and Therapy 2020, 13:1027-1035

Published Date: 3 February 2020

Original Research

The Ectopic Expression of SurvivinT34A and FilC Can Enhance the Oncolytic Effects of Vaccinia Virus in Murine Gastric Cancer

Wang M, Luo Y, Sun T, Mao C, Jiang Y, Yu X, Li Z, Xie T, Wu F, Yan H, Teng L

OncoTargets and Therapy 2020, 13:1011-1025

Published Date: 3 February 2020

Original Research

Circular RNA circ_0006282 Contributes to the Progression of Gastric Cancer by Sponging miR-155 to Upregulate the Expression of FBXO22

He Y, Wang Y, Liu L, Liu S, Liang L, Chen Y, Zhu Z

OncoTargets and Therapy 2020, 13:1001-1010

Published Date: 31 January 2020

Original Research

Meg3 Induces EMT and Invasion of Glioma Cells via Autophagy

Yang Z, Bian E, Xu Y, Ji X, Tang F, Ma C, Wang H, Zhao B

OncoTargets and Therapy 2020, 13:989-1000

Published Date: 31 January 2020

Original Research

MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1

Li C, Wang X, Song Q

OncoTargets and Therapy 2020, 13:981-988

Published Date: 31 January 2020

Case report

Primary Hepatic Neuroendocrine Tumor Mimicking Ruptured Hepatocellular Carcinoma with AFP Elevation: A Case Report and Literature Review

Huang H, Jin P, Yang H, Zhang C, Zhang X, Wang J, Yu J, Zhang B, Zhang Y, Hu Q

OncoTargets and Therapy 2020, 13:975-979

Published Date: 3 February 2020

Original Research

Bioactive Compounds from Abelmoschus manihot L. Alleviate the Progression of Multiple Myeloma in Mouse Model and Improve Bone Marrow Microenvironment

Hou J, Qian J, Li Z, Gong A, Zhong S, Qiao L, Qian S, Zhang Y, Dou R, Li R, Yang Y, Gu C

OncoTargets and Therapy 2020, 13:959-973

Published Date: 31 January 2020

Original Research

Biological and Clinical Significance of GATA3 Detected from TCGA Database and FFPE Sample in Bladder Cancer Patients

Wang C, Yang S, Jin L, Dai G, Yao Q, Xiang H, Zhang Y, Liu X, Xue B

OncoTargets and Therapy 2020, 13:945-958

Published Date: 31 January 2020

Original Research

MiR-195-5p Inhibits Malignant Progression of Cervical Cancer by Targeting YAP1

Liu X, Zhou Y, Ning Y, Gu H, Tong Y, Wang N

OncoTargets and Therapy 2020, 13:931-944

Published Date: 30 January 2020

Original Research

Long Noncoding RNA SNHG6 Functions as an Oncogene in Non-Small Cell Lung Cancer via Modulating ETS1 Signaling

Geng H, Li S, Xu M

OncoTargets and Therapy 2020, 13:921-930

Published Date: 30 January 2020

Case report

Testicular Metastasis from Urothelial Carcinoma of the Renal Pelvis: A Rare Case and Review of the Literature

Wu X, Zhang Y, Li Y, Li Y, Zhang X, Wang W, Ma J, Wang P, Dong Z, Shi W, Tian J

OncoTargets and Therapy 2020, 13:915-920

Published Date: 30 January 2020

Original Research

ST6GAL2 Downregulation Inhibits Cell Adhesion and Invasion and is Associated with Improved Patient Survival in Breast Cancer

Cheng J, Wang R, Zhong G, Chen X, Cheng Y, Li W, Yang Y

OncoTargets and Therapy 2020, 13:903-914

Published Date: 29 January 2020

Original Research

Sonophoresis Enhanced Transdermal Delivery of Cisplatin in the Xenografted Tumor Model of Cervical Cancer

Ma S, Liu C, Li B, Zhang T, Jiang L, Wang R

OncoTargets and Therapy 2020, 13:889-902

Published Date: 29 January 2020

Original Research

miR-31 Modulates Liver Cancer HepG2 Cell Apoptosis and Invasion via ROCK1/F-Actin Pathways

Zhang X, Xu L, Yang T

OncoTargets and Therapy 2020, 13:877-888

Published Date: 29 January 2020

Original Research

Nivolumab in Heavily Pretreated Metastatic Gastric Cancer Patients: Real-Life Data from a Western Population

Petrillo A, Tirino G, Zito Marino F, Pompella L, Sabetta R, Panarese I, Pappalardo A, Caterino M, Ventriglia A, Laterza MM, Morgillo F, Orditura M, Ciardiello F, Franco R, De Vita F

OncoTargets and Therapy 2020, 13:867-876

Published Date: 29 January 2020

Corrigendum

Upregulated LINC00565 Accelerates Ovarian Cancer Progression by Targeting GAS6 [Corrigendum]

Gong M, Luo C, Meng H, Li S, Nie S, Jiang Y, Wan Y, Li H, Cheng W

OncoTargets and Therapy 2020, 13:865-866

Published Date: 29 January 2020

Original Research

The Prognostic Impact of Hormonal Receptor and HER-2 Expression Discordance in Metastatic Breast Cancer Patients

Yang Z, Li N, Li X, Lei L, Wang X

OncoTargets and Therapy 2020, 13:853-863

Published Date: 28 January 2020

Review

From Anemia to Erythropoietin Resistance in Head and Neck Squamous Cell Carcinoma Treatment: A Carousel Driven by Hypoxia

Lazzari G, Silvano G

OncoTargets and Therapy 2020, 13:841-851

Published Date: 29 January 2020

Original Research

Dynamic Changes in Serum Markers and Their Utility in the Early Diagnosis of All Stages of Hepatitis B-Associated Hepatocellular Carcinoma

Wu M, Liu Z, Li X, Zhang A, Li N

OncoTargets and Therapy 2020, 13:827-840

Published Date: 28 January 2020

Original Research

Nucleolar and Spindle Associated Protein 1 (NUSAP1) Promotes Bladder Cancer Progression Through the TGF-β Signaling Pathway

Gao S, Yin H, Tong H, Zhan K, Yang G, Hossain MA, Li T, Gou X, He W

OncoTargets and Therapy 2020, 13:813-825

Published Date: 28 January 2020

Original Research

miR-214-3p Regulates Multi-Drug Resistance and Apoptosis in Retinoblastoma Cells by Targeting ABCB1 and XIAP

Yang L, Zhang L, Lu L, Wang Y

OncoTargets and Therapy 2020, 13:803-811

Published Date: 28 January 2020

Case report

A Rare Case of Moderately Differentiated Adenocarcinoma With PD-L1 Overexpression and a Heterogeneous LELC Component in the Ascending Colon

Nagano H, Watanabe T, Togawa T, Ohnishi K, Kimura T, Iida A, Sato Y, Goi T

OncoTargets and Therapy 2020, 13:791-801

Published Date: 28 January 2020

Case report

Entire ABL1 Gene Deletion Without BCR/ABL1 Rearrangement in a Female Patient with B-Cell Precursor Acute Lymphoblastic Leukemia

Jiang Y, Zhang J, Guo D, Zhang C, Hong L, Huang H, Liu H

OncoTargets and Therapy 2020, 13:783-790

Published Date: 24 January 2020

Original Research

MicroRNA-423 Drug Resistance and Proliferation of Breast Cancer Cells by Targeting ZFP36

Xia W, Liu Y, Du Y, Cheng T, Hu X, Li X

OncoTargets and Therapy 2020, 13:769-782

Published Date: 24 January 2020

Original Research

LncRNA SNHG1 Regulates the Progression of Esophageal Squamous Cell Cancer by the miR-204/HOXC8 Axis

Li HM, Yu YK, Liu Q, Wei XF, Zhang J, Zhang RX, Sun HB, Wang ZF, Xing WQ, Li Y

OncoTargets and Therapy 2020, 13:757-767

Published Date: 24 January 2020

Original Research

Hsa_circ_RNA_0011780 Represses the Proliferation and Metastasis of Non-Small Cell Lung Cancer by Decreasing FBXW7 via Targeting miR-544a

Liu Y, Yang C, Cao C, Li Q, Jin X, Shi H

OncoTargets and Therapy 2020, 13:745-755

Published Date: 23 January 2020

Original Research

Acetyl-11-Keto-β-Boswellic Acid Exerts the Anti-Cancer Effects via Cell Cycle Arrest, Apoptosis Induction and Autophagy Suppression in Non-Small Cell Lung Cancer Cells

Lv M, Shao S, Zhang Q, Zhuang X, Qiao T

OncoTargets and Therapy 2020, 13:733-744

Published Date: 23 January 2020

Review

Clinical Applications of Cerebrospinal Fluid Circulating Tumor DNA as a Liquid Biopsy for Central Nervous System Tumors

Yan W, Xu T, Zhu H, Yu J

OncoTargets and Therapy 2020, 13:719-731

Published Date: 23 January 2020

Original Research

KNDC1 Is a Predictive Marker of Malignant Transformation in Borderline Ovarian Tumors

Yu S, Shen J, Fei J, Zhu X, Yin M, Zhou J

OncoTargets and Therapy 2020, 13:709-718

Published Date: 23 January 2020

Original Research

MLPH Accelerates the Epithelial–Mesenchymal Transition in Prostate Cancer

Zhang T, Sun Y, Zheng T, Wang R, Jia D, Zhang W

OncoTargets and Therapy 2020, 13:701-708

Published Date: 23 January 2020

Original Research

Long Noncoding RNA SNHG7, a Molecular Sponge for microRNA-485, Promotes the Aggressive Behavior of Cervical Cancer by Regulating PAK4

Wu F, Sui Y, Wang Y, Xu T, Fan L, Zhu H

OncoTargets and Therapy 2020, 13:685-699

Published Date: 23 January 2020

Review

Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer

Wang S, Hu C, Xie F, Liu Y

OncoTargets and Therapy 2020, 13:667-683

Published Date: 23 January 2020

Original Research

SNHG15 Contributes To Cisplatin Resistance In Breast Cancer Through Sponging miR-381

Mi H, Wang X, Wang F, Li L, Zhu M, Wang N, Xiong Y, Gu Y

OncoTargets and Therapy 2020, 13:657-666

Published Date: 21 January 2020

Case Series

Dual Targeting of the Epidermal Growth Factor Receptor Using Combination of Nimotuzumab and Erlotinib in Advanced Non-Small-Cell Lung Cancer with Leptomeningeal Metastases: A Report of Three Cases

Xu H, Zhou L, Lu Y, Su X, Cheng P, Li D, Gao H, Li H, Yuan W, Zhang L, Zhang T

OncoTargets and Therapy 2020, 13:647-656

Published Date: 21 January 2020

Original Research

Comparison of Gut Microbiome in Human Colorectal Cancer in Paired Tumor and Adjacent Normal Tissues

Sheng QS, He KX, Li JJ, Zhong ZF, Wang FX, Pan LL, Lin JJ

OncoTargets and Therapy 2020, 13:635-646

Published Date: 21 January 2020

Original Research

FOXK1, Regulated by miR-365-3p, Promotes Cell Growth and EMT Indicates Unfavorable Prognosis in Breast Cancer

Gao F, Tian J

OncoTargets and Therapy 2020, 13:623-634

Published Date: 21 January 2020

Original Research

Prevalence of ESR1 Mutation in Chinese ER-Positive Breast Cancer

Zhu W, Ren C, Wang Y, Wen L, Zhang G, Liao N

OncoTargets and Therapy 2020, 13:615-621

Published Date: 21 January 2020

Original Research

Clinical Outcomes and Safety of Apatinib Mesylate in the Treatment of Advanced Non-Squamous Non-Small Cell Lung Cancer in Patients Who Progressed After Standard Therapy and Analysis of the KDR Gene Polymorphism

Song ZZ, Zhao LF, Zuo J, Fan ZS, Wang L, Wang YD

OncoTargets and Therapy 2020, 13:603-613

Published Date: 21 January 2020

Original Research

miR-100 Inhibits Cell Growth and Proliferation by Targeting HOXA1 in Nasopharyngeal Carcinoma

He W, Huang Y, Jiang C, Zhu Y, Wang L, Zhang W, Huang W, Zhou T, Tang S

OncoTargets and Therapy 2020, 13:593-602

Published Date: 20 January 2020

Case report

The Expressions of Keratins and P63 in Primary Squamous Cell Carcinoma of the Thyroid Gland: An Application of Raman Spectroscopy

Wang S, Ye D, Wang B, Xie C

OncoTargets and Therapy 2020, 13:585-591

Published Date: 20 January 2020

Original Research

LncRNA-ATB Promotes the Tumorigenesis of Ovarian Cancer via Targeting miR-204-3p

Yuan D, Qian H, Guo T, Ye J, Jin C, Liu X, Jiang L, Wang X, Lin M, Yu H

OncoTargets and Therapy 2020, 13:573-583

Published Date: 20 January 2020

Original Research

Silencing of LncRNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 Inhibits the Proliferation and Promotes the Apoptosis of Gastric Cancer Cells Through Regulating microRNA-22-3p-Mediated ErbB3

Li X, Zhao J, Zhang H, Cai J

OncoTargets and Therapy 2020, 13:559-571

Published Date: 20 January 2020

Original Research

circGFRA1 Enhances NSCLC Progression by Sponging miR-188-3p

Yao J, Xu G, Zhu L, Zheng H

OncoTargets and Therapy 2020, 13:549-558

Published Date: 20 January 2020

Original Research

Plasma Messenger RNAs Identified Through Bioinformatics Analysis are Novel, Non-Invasive Prostate Cancer Biomarkers

Wang R, Wu Y, Yu J, Yang G, Yi H, Xu B

OncoTargets and Therapy 2020, 13:541-548

Published Date: 17 January 2020

Review

Self-Renewal Signalling Pathway Inhibitors: Perspectives on Therapeutic Approaches for Cancer Stem Cells

Zhu Q, Shen Y, Chen X, He J, Liu J, Zu X

OncoTargets and Therapy 2020, 13:525-540

Published Date: 16 January 2020

Original Research

Quercetin Enhanced Paclitaxel Therapeutic Effects Towards PC-3 Prostate Cancer Through ER Stress Induction and ROS Production

Zhang X, Huang J, Yu C, Xiang L, Li L, Shi D, Lin F

OncoTargets and Therapy 2020, 13:513-523

Published Date: 16 January 2020

Original Research

Silencing Snail Reverses Epithelial-Mesenchymal Transition and Increases Radiosensitivity in Hypopharyngeal Carcinoma

Wang H, Wang Z, Li Y, Lu T, Hu G

OncoTargets and Therapy 2020, 13:497-511

Published Date: 16 January 2020

Original Research

Preparation and SPECT/CT Imaging of 177Lu-Labeled Peptide Nucleic Acid (PNA) Targeting CITED1: Therapeutic Evaluation in Tumor-Bearing Nude Mice

Li J, Zhang L, Li W, Lei C, Cao Y, Wang Y, Wang Z, Pang H

OncoTargets and Therapy 2020, 13:487-496

Published Date: 15 January 2020

Original Research

The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis

Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X

OncoTargets and Therapy 2020, 13:473-486

Published Date: 15 January 2020

Original Research

HMGA2 Gene rs8756 A>C Polymorphism Reduces Neuroblastoma Risk in Chinese Children: A Four-Center Case-Control Study

Liu J, Hua RX, Cheng Y, Zhu J, Zhang J, Cheng J, Zhou H, Xia H, Bian J, He J

OncoTargets and Therapy 2020, 13:465-472

Published Date: 15 January 2020

Original Research

FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway

Zheng P, Li L

OncoTargets and Therapy 2020, 13:451-463

Published Date: 15 January 2020

Original Research

Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells

Saleem MZ, Nisar MA, Alshwmi M, Din SRU, Gamallat Y, Khan M, Ma T

OncoTargets and Therapy 2020, 13:435-450

Published Date: 15 January 2020

Original Research

Circular RNA circHUWE1 Is Upregulated and Promotes Cell Proliferation, Migration and Invasion in Colorectal Cancer by Sponging miR-486

Chen HY, Li XN, Ye CX, Chen ZL, Wang ZJ

OncoTargets and Therapy 2020, 13:423-434

Published Date: 14 January 2020

Original Research

LncRNA SNHG11 Promotes Proliferation, Migration, Apoptosis, and Autophagy by Regulating hsa-miR-184/AGO2 in HCC

Huang W, Huang F, Lei Z, Luo H

OncoTargets and Therapy 2020, 13:413-421

Published Date: 14 January 2020

Original Research

PHLPP Sensitizes Multiple Myeloma Cells to Bortezomib Through Regulating LAMP2

Liu X, Li C, Fu Y, Liu J

OncoTargets and Therapy 2020, 13:401-411

Published Date: 14 January 2020

Original Research

miR-939-5p Contributes to the Migration and Invasion of Pancreatic Cancer by Targeting ARHGAP4

Shen Y, Chen G, Gao H, Li Y, Zhuang L, Meng Z, Liu L

OncoTargets and Therapy 2020, 13:389-399

Published Date: 14 January 2020

Original Research

ASH2L-Promoted HOXC8 Gene Expression Plays a Role in Mixed Lineage Leukemia-Rearranged Acute Leukemia

Wu YJ, Li L, Liu L, Zhao S, Qiu H, Wang H

OncoTargets and Therapy 2020, 13:381-387

Published Date: 14 January 2020

Original Research

RING Finger Protein 38 Mediates LIM Domain Binding 1 Degradation and Regulates Cell Growth in Colorectal Cancer

Huang Z, Yang P, Ge H, Yang C, Cai Y, Chen Z, Tian W, Wang H

OncoTargets and Therapy 2020, 13:371-379

Published Date: 14 January 2020

Original Research

Propofol Inhibits the Migration and Invasion of Glioma Cells by Blocking the PI3K/AKT Pathway Through miR-206/ROCK1 Axis

Wang D, Yang T, Liu J, Liu Y, Xing N, He J, Yang J, Ai Y

OncoTargets and Therapy 2020, 13:361-370

Published Date: 14 January 2020

Original Research

SPOCD1 accelerates ovarian cancer progression and inhibits cell apoptosis via the PI3K/AKT pathway

Liu D, Yang Y, Yan A, Yang Y

OncoTargets and Therapy 2020, 13:351-359

Published Date: 15 January 2020

Original Research

Silencing of Long Non-Coding RNA Colon Cancer-Associated Transcript 2 Inhibits the Growth and Metastasis of Gastric Cancer Through Blocking mTOR Signaling

Lin S, Wang H, Yang W, Wang A, Geng C

OncoTargets and Therapy 2020, 13:337-349

Published Date: 13 January 2020

Original Research

Transcriptome Analysis Reveals Key Genes and Pathways Associated with Metastasis in Breast Cancer

Li W, Liu J, Zhang B, Bie Q, Qian H, Xu W

OncoTargets and Therapy 2020, 13:323-335

Published Date: 13 January 2020

Original Research

Nomograms for Prediction of Molecular Phenotypes in Colorectal Cancer

Yu Z, Yu H, Zou Q, Huang Z, Wang X, Tang G, Bai L, Zhou C, Zhuang Z, Xie Y, Wang H, Xu G, Chen Z, Fu X, Huang M, Luo Y

OncoTargets and Therapy 2020, 13:309-321

Published Date: 13 January 2020

Original Research

Icariin Mitigates the Growth and Invasion Ability of Human Oral Squamous Cell Carcinoma via Inhibiting Toll-Like Receptor 4 and Phosphorylation of NF-κB P65

Lei K, Ma B, Shi P, Jin C, Ling T, Li L, He X, Wang L

OncoTargets and Therapy 2020, 13:299-307

Published Date: 10 January 2020

Original Research

Tizanidine (Hydrochloride) Inhibits A549 Lung Cancer Cell Proliferation and Motility Through Regulating Nischarin

Zhao L, Zhao G, Xue Q

OncoTargets and Therapy 2020, 13:291-298

Published Date: 10 January 2020

Original Research

Inhibition of TRIM32 Induced by miR-519d Increases the Sensitivity of Colorectal Cancer Cells to Cisplatin

Su X, Wang B, Wang Y, Wang B

OncoTargets and Therapy 2020, 13:277-289

Published Date: 10 January 2020

Original Research

Long Non Coding RNA SNHG16 Facilitates Proliferation, Migration, Invasion and Autophagy of Neuroblastoma Cells via Sponging miR-542-3p and Upregulating ATG5 Expression

Wen Y, Gong X, Dong Y, Tang C

OncoTargets and Therapy 2020, 13:263-275

Published Date: 10 January 2020

Original Research

Repression of PCGF1 Decreases the Proliferation of Glioblastoma Cells in Association with Inactivation of c-Myc Signaling Pathway

Yan R, Cui F, Dong L, Liu Y, Chen X, Fan R

OncoTargets and Therapy 2020, 13:253-261

Published Date: 9 January 2020

Original Research

LncRNA PVT1 Enhances Proliferation and Cisplatin Resistance via Regulating miR-194-5p/HIF1a Axis in Oral Squamous Cell Carcinoma

Wang F, Ji X, Wang J, Ma X, Yang Y, Zuo J, Cui J

OncoTargets and Therapy 2020, 13:243-252

Published Date: 9 January 2020

Case report

Urgent Chemotherapy Successfully Rescues a Near Death Patient of Acute Intracranial Hypertension Caused by Intracranial Myeloid Sarcoma

Zhou L, Zhang X, Feng S, Zhao N, Hu X, Huang L, Zheng C

OncoTargets and Therapy 2020, 13:237-241

Published Date: 9 January 2020

Original Research

MicroRNA-708 Suppresses Cell Proliferation and Enhances Chemosensitivity of Cervical Cancer Cells to cDDP by Negatively Targeting Timeless

Zou X, Zhu C, Zhang L, Zhang Y, Fu F, Chen Y, Zhou J

OncoTargets and Therapy 2020, 13:225-235

Published Date: 9 January 2020

Original Research

BTLA Expression in Stage I–III Non–Small-Cell Lung Cancer and Its Correlation with PD-1/PD-L1 and Clinical Outcomes

Li X, Xu Z, Cui G, Yu L, Zhang X

OncoTargets and Therapy 2020, 13:215-224

Published Date: 9 January 2020

Original Research

The Clinical Significance of PPEF1 as a Promising Biomarker and Its Potential Mechanism in Breast Cancer

Ye T, Wan X, Li J, Feng J, Guo J, Li G, Liu J

OncoTargets and Therapy 2020, 13:199-214

Published Date: 8 January 2020

Original Research

The Roles of Ubiquitination Factor E4B (UBE4B) in the Postoperative Prognosis of Patients with Renal Cell Carcinoma and in Renal Tumor Cells Growth and Metastasis

Huang XQ, Hao S, Zhou ZQ, Huang B, Fang JY, Tang Y, Zhang JH, Xia JC

OncoTargets and Therapy 2020, 13:185-197

Published Date: 8 January 2020

Original Research

Knockdown of LINC00473 Enhances Radiosensitivity in Hepatocellular Carcinoma via Regulating the miR-345-5p/FOXP1 Axis

Zhang Y, Huang B, Chen Z, Yang S

OncoTargets and Therapy 2020, 13:173-183

Published Date: 8 January 2020

Original Research

lncRNA FLVCR-AS1 promotes osteosarcoma growth by targeting miR381-3p/CCND1

Yang G, He F, Duan H, Shen J, Dong Q

OncoTargets and Therapy 2020, 13:163-172

Published Date: 9 January 2020

Original Research

Predictive Value of Lymphocyte-Related Blood Parameters at the Time Point of Lymphocyte Nadir During Radiotherapy in Breast Cancer

Liu J, Ma F, Sun B, Cong Y, Xuan L, Wang Q, Wu S

OncoTargets and Therapy 2020, 13:151-161

Published Date: 8 January 2020

Original Research

Programmed Cell Death Protein-1 (PD-1)-Targeted Immunotherapy for Advanced Hepatocellular Carcinoma in Real World

Cui H, Dai G, Guan J

OncoTargets and Therapy 2020, 13:143-149

Published Date: 8 January 2020

Original Research

Long Non-Coding RNA PVT1 Regulates BAMBI To Promote Tumor Progression In Non-Small Cell Lung Cancer By Sponging miR-17-5p

Wang Z, Zhang Q, Sun Y, Shao F

OncoTargets and Therapy 2020, 13:131-142

Published Date: 7 January 2020

Original Research

Upregulated lncRNA THRIL/TNF-α Signals Promote Cell Growth and Predict Poor Clinical Outcomes of Osteosarcoma

Xu B, Jin X, Yang T, Zhang Y, Liu S, Wu L, Ying H, Wang Z

OncoTargets and Therapy 2020, 13:119-129

Published Date: 7 January 2020

Original Research

miR-1269b Drives Cisplatin Resistance of Human Non-Small Cell Lung Cancer via Modulating the PTEN/PI3K/AKT Signaling Pathway

Yang W, Xiao W, Cai Z, Jin S, Li T

OncoTargets and Therapy 2020, 13:109-118

Published Date: 7 January 2020

Original Research

Prognostic Correlation of Autophagy-Related Gene Expression-Based Risk Signature in Patients with Glioblastoma

Wang QW, Liu HJ, Zhao Z, Zhang Y, Wang Z, Jiang T, Bao ZS

OncoTargets and Therapy 2020, 13:95-107

Published Date: 7 January 2020

Review

Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle

Zhuang Y, Liu C, Liu J, Li G

OncoTargets and Therapy 2020, 13:83-94

Published Date: 7 January 2020

Original Research

FOXN4 Inhibits Breast Cancer Progression By Direct Activation Of P53

Ye H, Duan M

OncoTargets and Therapy 2020, 13:71-81

Published Date: 7 January 2020

Original Research

Exon Coverage Variations Between Cancer Tissues and Adjacent Non-Cancerous Tissues are Prognostic Factors in Gastric Cancer

Pan X, Wang Y, Li C, Zhou Z, Zhong Y, Feng J, Lu J

OncoTargets and Therapy 2020, 13:61-70

Published Date: 7 January 2020

Original Research

Up-Regulated CCDC34 Contributes to the Proliferation and Metastasis of Hepatocellular Carcinoma

Lin Z, Qu S, Peng W, Yang P, Zhang R, Zhang P, Guo D, Du J, Wu W, Tao K, Wang J

OncoTargets and Therapy 2020, 13:51-60

Published Date: 7 January 2020

Original Research

Metformin Inhibits Proliferation of Human Thyroid Cancer TPC-1 Cells by Decreasing LRP2 to Suppress the JNK Pathway

He Y, Cao L, Wang L, Liu L, Huang Y, Gong X

OncoTargets and Therapy 2020, 13:45-50

Published Date: 6 January 2020

Original Research

Dioscin Inhibited Glycolysis and Induced Cell Apoptosis in Colorectal Cancer via Promoting c-myc Ubiquitination and Subsequent Hexokinase-2 Suppression

Wu Z, Han X, Tan G, Zhu Q, Chen H, Xia Y, Gong J, Wang Z, Wang Y, Yan J

OncoTargets and Therapy 2020, 13:31-44

Published Date: 6 January 2020

Original Research

Cas9 Mediated Correction of β-catenin Mutation and Restoring the Expression of Protein Phosphorylation in Colon Cancer HCT-116 Cells Decrease Cell Proliferation in vitro and Hamper Tumor Growth in Mice in vivo

Li Y, Li X, Qu J, Luo D, Hu Z

OncoTargets and Therapy 2020, 13:17-29

Published Date: 6 January 2020

Review

Optimal Management of Upper Tract Urothelial Carcinoma: Current Perspectives

Leow JJ, Liu Z, Tan TW, Lee YM, Yeo EK, Chong YL

OncoTargets and Therapy 2020, 13:1-15

Published Date: 6 January 2020

Original Research

Circular RNA PVT1 promotes the invasion and epithelial–mesenchymal transition of breast cancer cells through serving as a competing endogenous RNA for miR-204-5p

Bian Q

OncoTargets and Therapy 2019, 12:11817-11826

Published Date: 7 July 2020

Review

miRNAs: A Promising Target in the Chemoresistance of Bladder Cancer

Cai Z, Zhang F, Chen W, Zhang J, Li H

OncoTargets and Therapy 2019, 12:11805-11816

Published Date: 3 January 2020

Review

Epstein-Barr Virus-Encoded Products Promote Circulating Tumor Cell Generation: A Novel Mechanism of Nasopharyngeal Carcinoma Metastasis

Yang Z, Wang J, Zhang Z, Tang F

OncoTargets and Therapy 2019, 12:11793-11804

Published Date: 6 January 2020

Original Research

Identification of the Different Roles and Potential Mechanisms of T Isoforms in the Tumor Recurrence and Cell Cycle of Chordomas

Ma J, Chen W, Wang K, Tian K, Li Q, Zhao T, Zhang L, Wang L, Wu Z, Zhang J

OncoTargets and Therapy 2019, 12:11777-11791

Published Date: 3 January 2020

Original Research

Midkine Is a Potential Urinary Biomarker for Non-Invasive Detection of Bladder Cancer with Microscopic Hematuria

Lin H, Zhou Q, Wu W, Ma Y

OncoTargets and Therapy 2019, 12:11765-11775

Published Date: 3 January 2020

Original Research

Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake

Zhang P, Wang Q, Lin Z, Yang P, Dou K, Zhang R

OncoTargets and Therapy 2019, 12:11751-11763

Published Date: 3 January 2020

Original Research

MicroRNA-769-5p Inhibits Pancreatic Ductal Adenocarcinoma Progression by Directly Targeting and Downregulating ETS Proto-Oncogene 1

Cheng K, Feng L, Yu S, Yu C, Chi N

OncoTargets and Therapy 2019, 12:11737-11750

Published Date: 3 January 2020

Original Research

Expression and Effects of Long Non-Coding RNA, LINC01124, in Non-Small Cell Lung Cancer

Wang ZB, Zhang HY, Lu JB

OncoTargets and Therapy 2019, 12:11729-11736

Published Date: 3 January 2020

Original Research

Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells

Shi S, Zheng G, Yang C, Chen X, Yan Q, Jiang F, Jiang X, Xin Y, Jiang G

OncoTargets and Therapy 2019, 12:11715-11727

Published Date: 3 January 2020

Original Research

LncRNA FTX Promotes Proliferation and Invasion of Gastric Cancer via miR-144/ZFX Axis

Li H, Yao G, Zhai J, Hu D, Fan Y

OncoTargets and Therapy 2019, 12:11701-11713

Published Date: 31 December 2019

Original Research

miR-520b Promotes Breast Cancer Stemness Through Hippo/YAP Signaling Pathway

Zhang H, Lang T, Zou D, Zhou L, Lou M, Liu J, Li Y, Ding D, Li Y, Zhang N, Zheng X, Zeng X, Zhou Q, Li L

OncoTargets and Therapy 2019, 12:11691-11700

Published Date: 31 December 2019

Review

SNHG16: A Novel Long-Non Coding RNA in Human Cancers

Yang M, Wei W

OncoTargets and Therapy 2019, 12:11679-11690

Published Date: 31 December 2019

Original Research

A Chemotherapy-Driven Increase in Mcl-1 Mediates the Effect of miR-375 on Cisplatin Resistance in Osteosarcoma Cells

Liu A, Yu H, Yang Y, Xue F, Chen X, Zhang Y, Zhou Z, Zhang B, Li L, Sun C, Huang P, Huang J

OncoTargets and Therapy 2019, 12:11667-11677

Published Date: 31 December 2019

Original Research

Water Extract of Sporoderm-Broken Spores of Ganoderma lucidum Induces Osteosarcoma Apoptosis and Restricts Autophagic Flux

Zhang W, Lei Z, Meng J, Li G, Zhang Y, He J, Yan W

OncoTargets and Therapy 2019, 12:11651-11665

Published Date: 31 December 2019

Original Research

DUXAP8 a Pan-Cancer Prognostic Marker Involved in the Molecular Regulatory Mechanism in Hepatocellular Carcinoma: A Comprehensive Study Based on Data Mining, Bioinformatics, and in vitro Validation

Yue C, Liang C, Li P, Yan L, Zhang D, Xu Y, Wei Z, Wu J

OncoTargets and Therapy 2019, 12:11637-11650

Published Date: 31 December 2019

Original Research

Long Non-Coding RNA EGOT Promotes the Malignant Phenotypes of Hepatocellular Carcinoma Cells and Increases the Expression of HMGA2 via Down-Regulating miR-33a-5p

Wu S, Ai H, Zhang K, Yun H, Xie F

OncoTargets and Therapy 2019, 12:11623-11635

Published Date: 31 December 2019

Original Research

Potential Prognostic and Diagnostic Values of CDC6, CDC45, ORC6 and SNHG7 in Colorectal Cancer

Hu Y, Wang L, Li Z, Wan Z, Shao M, Wu S, Wang G

OncoTargets and Therapy 2019, 12:11609-11621

Published Date: 31 December 2019

Original Research

Identification of an Activating Mutation in the Extracellular Domain of HER2 Conferring Resistance to Pertuzumab

Zhang Y, Wu S, Zhuang X, Weng G, Fan J, Yang X, Xu Y, Pan L, Hou T, Zhou Z, Chen S

OncoTargets and Therapy 2019, 12:11597-11608

Published Date: 30 December 2019

Original Research

TRIM3 Negatively Regulates Autophagy Through Promoting Degradation of Beclin1 in Ewing Sarcoma Cells

Lu Q, Zhang Y, Ma L, Li D, Li M, Liu P, Li J

OncoTargets and Therapy 2019, 12:11587-11595

Published Date: 30 December 2019

Original Research

Resveratrol Inhibits Proliferation in HBL-52 Meningioma Cells

Hu S, Wei W, Yuan J, Cheng J

OncoTargets and Therapy 2019, 12:11579-11586

Published Date: 30 December 2019

Original Research

Prognostic Significance of FKBP14 in Gastric Cancer

Ghoorun RA, Wu XH, Chen HL, Ren DL, Wu XB

OncoTargets and Therapy 2019, 12:11567-11577

Published Date: 30 December 2019

Original Research

microRNA-26a-5p Promotes Proliferation and Migration of Osteosarcoma Cells by Targeting HOXA5 in vitro and in vivo

Yu T, Chen D, Zhang L, Wan D

OncoTargets and Therapy 2019, 12:11555-11565

Published Date: 30 December 2019

Case report

Primary Prostatic Extra-Gastrointestinal Stromal Tumor Treated with Imatinib Mesylate as Neoadjuvant and Adjuvant Therapy: A Case Report and Literature Review

Shen H, Wang Z, Feng M, Liu J, Li J, Wang X, Xu X

OncoTargets and Therapy 2019, 12:11549-11553

Published Date: 30 December 2019

Original Research

Conformance Assessment of PD-L1 Expression Between Primary Tumour and Nodal Metastases in Non-Small-Cell Lung Cancer

Xu H, Chen X, Lin D, Zhang J, Li C, Zhang D, Zhang X

OncoTargets and Therapy 2019, 12:11541-11547

Published Date: 30 December 2019

Original Research

Long Non-Coding RNA TTN-AS1 Promotes the Proliferation and Invasion of Colorectal Cancer Cells by Activating miR-497-Mediated PI3K/Akt/mTOR Signaling

Cui Z, Han B, Wang X, Li Z, Wang J, Lv Y

OncoTargets and Therapy 2019, 12:11531-11539

Published Date: 27 December 2019

Review

Circulating Cell-Free DNA or Circulating Tumor DNA in the Management of Ovarian and Endometrial Cancer

Chen Q, Zhang ZH, Wang S, Lang JH

OncoTargets and Therapy 2019, 12:11517-11530

Published Date: 27 December 2019

Original Research

ARHGAP10 Inhibits the Proliferation and Metastasis of CRC Cells via Blocking the Activity of RhoA/AKT Signaling Pathway

Liu L, Xie D, Xie H, Huang W, Zhang J, Jin W, Jiang W, Xie D

OncoTargets and Therapy 2019, 12:11507-11516

Published Date: 27 December 2019

Review

Role of Olaparib as Maintenance Treatment for Ovarian Cancer: The Evidence to Date

Montemorano L, Lightfoot MDS, Bixel K

OncoTargets and Therapy 2019, 12:11497-11506

Published Date: 27 December 2019

Original Research

LncRNA SNHG5 Promotes Proliferation of Glioma by Regulating miR-205-5p/ZEB2 Axis

Meng X, Deng Y, Lv Z, Liu C, Guo Z, Li Y, Liu H, Xie B, Jin Z, Lin F, Zhu H

OncoTargets and Therapy 2019, 12:11487-11496

Published Date: 27 December 2019

Original Research

IRF1 Negatively Regulates Oncogenic KPNA2 Expression Under Growth Stimulation and Hypoxia in Lung Cancer Cells

Huang JX, Wu YC, Cheng YY, Wang CL, Yu CJ

OncoTargets and Therapy 2019, 12:11475-11486

Published Date: 27 December 2019

Original Research

MiR-195-5p Inhibits Proliferation and Induces Apoptosis of Non-Small Cell Lung Cancer Cells by Targeting CEP55

Luo J, Pan J, Jin Y, Li M, Chen M

OncoTargets and Therapy 2019, 12:11465-11474

Published Date: 24 December 2019

Original Research

miR-492 Promotes Cancer Progression by Targeting GJB4 and Is a Novel Biomarker for Bladder Cancer

Wang K, Lü H, Qu H, Xie Q, Sun T, Gan O, Hu B

OncoTargets and Therapy 2019, 12:11453-11464

Published Date: 24 December 2019

Original Research

Berbamine Enhances the Efficacy of Gefitinib by Suppressing STAT3 Signaling in Pancreatic Cancer Cells

Hu B, Cai H, Yang S, Tu J, Huang X, Chen G

OncoTargets and Therapy 2019, 12:11437-11451

Published Date: 24 December 2019

Original Research

miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4

Chen S, Zhang JY, Sun LS, Li XF, Bai JY, Zhang HY, Li TJ

OncoTargets and Therapy 2019, 12:11425-11436

Published Date: 24 December 2019

Original Research

A Novel Scoring System Based on Peripheral Blood Test in Predicting Grade and Prognosis of Patients with Glioma

Wu Y, Song Z, Sun K, Rong S, Gao P, Wang F, Sun T

OncoTargets and Therapy 2019, 12:11413-11423

Published Date: 24 December 2019

Review

Research Progress in microRNA-Based Therapy for Gastric Cancer

Zhao X, Hu GF, Shi YF, Xu W

OncoTargets and Therapy 2019, 12:11393-11411

Published Date: 24 December 2019

Original Research

Evodiamine Selectively Inhibits Multiple Myeloma Cell Growth by Triggering Activation of Intrinsic Apoptosis Pathway

Fang Q, Jiang S, Li C

OncoTargets and Therapy 2019, 12:11383-11391

Published Date: 24 December 2019

Original Research

TMEFF2 inhibits pancreatic cancer cells proliferation, migration, and invasion by suppressing phosphorylation of the MAPK signaling pathway

Han H, Zhan Z, Xu J, Song Z

OncoTargets and Therapy 2019, 12:11371-11382

Published Date: 23 December 2019

Original Research

Cystatin SN Affects Cell Proliferation by Regulating the ERα/PI3K/AKT/ERα Loopback Pathway in Breast Cancer

Liu Y, Ma H, Wang Y, Du X, Yao J

OncoTargets and Therapy 2019, 12:11359-11369

Published Date: 23 December 2019

Original Research

LOXL1-AS1 Drives The Progression Of Gastric Cancer Via Regulating miR-142-5p/PIK3CA Axis

Li M, Cai O, Tan S

OncoTargets and Therapy 2019, 12:11345-11357

Published Date: 20 December 2019

Case report

Application of Somatostatin, Chemotherapy Combined with TAE in Heterogeneous Glucagonoma Presented with Necrolytic Migratory Erythema

Shen C, He J, Le X, Zheng L, Cao D

OncoTargets and Therapy 2019, 12:11339-11344

Published Date: 20 December 2019

Original Research

Exosome-Mediated Transfer of lncRNA HOTTIP Promotes Cisplatin Resistance in Gastric Cancer Cells by Regulating HMGA1/miR-218 Axis

Wang J, Lv B, Su Y, Wang X, Bu J, Yao L

OncoTargets and Therapy 2019, 12:11325-11338

Published Date: 20 December 2019

Original Research

miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells

Wang Y, Wang F, He J, Du J, Zhang H, Shi H, Chen Y, Wei Y, Xue W, Yan J, Feng Y, Gao Y, Li D, Han J, Zhang J

OncoTargets and Therapy 2019, 12:11313-11324

Published Date: 19 December 2019

Case report

Third-Generation TKI Resistance Due to SCLC Transformation: A Case Report and Brief Review

Chen S, He Y, Liu J, Chen X, Yu J, Li W, Chen B, Sun C, Zhou C

OncoTargets and Therapy 2019, 12:11305-11311

Published Date: 19 December 2019

Review

Ferroptosis in Carcinoma: Regulatory Mechanisms and New Method for Cancer Therapy

Shi ZZ, Fan ZW, Chen YX, Xie XF, Jiang W, Wang WJ, Qiu YT, Bai J

OncoTargets and Therapy 2019, 12:11291-11304

Published Date: 19 December 2019

Original Research

MAGI1 Inhibits the Proliferation, Migration and Invasion of Glioma Cells

Li ZY, Li XH, Tian GW, Zhang DY, Gao H, Wang ZY

OncoTargets and Therapy 2019, 12:11281-11290

Published Date: 19 December 2019

Original Research

MicroRNA-432 Suppresses Invasion and Migration via E2F3 in Nasopharyngeal Carcinoma

Wang T, Du M, Zhang W, Bai H, Yin L, Chen W, He X, Chen Q

OncoTargets and Therapy 2019, 12:11271-11280

Published Date: 19 December 2019

Original Research

Demethylation and Overexpression of CSF2 are Involved in Immune Response, Chemotherapy Resistance, and Poor Prognosis in Colorectal Cancer

Xu Z, Zhang Y, Xu M, Zheng X, Lin M, Pan J, Ye C, Deng Y, Jiang C, Lin Y, Lu X, Chi P

OncoTargets and Therapy 2019, 12:11255-11269

Published Date: 19 December 2019

Original Research

Upregulated miR-27a-3p Indicates a Poor Prognosis in Pancreatic Carcinoma Patients and Promotes the Angiogenesis and Migration by Epigenetic Silencing of GATA6 and Activating VEGFA/VEGFR2 Signaling Pathway

Rao X, Wan L, Jie Z, Zhu X, Yin J, Cao H

OncoTargets and Therapy 2019, 12:11241-11254

Published Date: 19 December 2019

Original Research

Aberrant Expression of miR-592 Is Associated with Prognosis and Progression of Renal Cell Carcinoma

Lv X, Shen J, Guo Z, Kong L, Zhou G, Ning H

OncoTargets and Therapy 2019, 12:11231-11239

Published Date: 18 December 2019

Original Research

RNA-Seq Analysis Identified XLOC_009190 as Potential Therapeutic Target for Lung Adenocarcinoma

Wang J, Wang N, Zhao W, Zhao L, Jing Y, Yang L, He J, Li J

OncoTargets and Therapy 2019, 12:11221-11229

Published Date: 18 December 2019

Original Research

MTF2 Induces Epithelial-Mesenchymal Transition and Progression of Hepatocellular Carcinoma by Transcriptionally Activating Snail

Wu TT, Cai J, Tian YH, Chen JF, Cheng ZL, Pu CS, Shi WZ, Suo XP, Wu XJ, Dou XW, Zhang KM

OncoTargets and Therapy 2019, 12:11207-11220

Published Date: 17 December 2019

Original Research

Long Non-Coding RNA HOXA11-AS Promotes Non-Small Cell Lung Cancer Tumorigenesis Through microRNA-148a-3p/DNMT1 Regulatory Axis

Bai Y, Lang L, Zhao W, Niu R

OncoTargets and Therapy 2019, 12:11195-11206

Published Date: 17 December 2019

Original Research

Baicalin Inhibits Cell Viability, Migration and Invasion in Breast Cancer by Regulating miR-338-3p and MORC4

Duan X, Guo G, Pei X, Wang X, Li L, Xiong Y, Qiu X

OncoTargets and Therapy 2019, 12:11183-11193

Published Date: 17 December 2019

Original Research

Notch Intracellular Domain (NICD) Expression and Clinical Manifestations of Second Primary Tumor at Esophagus in Patients with Head and Neck Squamous Cell Carcinoma

Anekpuritanang T, Pongsapich W, Watcharadilokkul T, Ngaotepprutaram P, Pithuksurachai P, Bunbanjerdsuk S

OncoTargets and Therapy 2019, 12:11175-11181

Published Date: 17 December 2019

Original Research

Impact of Fucosylation on Self-Assembly of Prostate and Breast Tumor Spheroids by Using Cyclo-RGDfK(TPP) Peptide and Image Object Detection

Kalaydina RV, Zhou H, Markvicheva E, Burov SV, Zulkernine F, Szewczuk MR

OncoTargets and Therapy 2019, 12:11153-11173

Published Date: 17 December 2019

Case report

Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report

Chen J, Mu F, Lu T, Du D, Xu K

OncoTargets and Therapy 2019, 12:11145-11151

Published Date: 17 December 2019

Review

Oral Microbiota as Promising Diagnostic Biomarkers for Gastrointestinal Cancer: A Systematic Review

Chen Y, Chen X, Yu H, Zhou H, Xu S

OncoTargets and Therapy 2019, 12:11131-11144

Published Date: 18 December 2019

Original Research

LncRNA LINC00461 Promotes Colorectal Cancer Progression via miRNA-323b-3p/NFIB Axis

Yu H, Ma J, Chen J, Yang Y, Liang J, Liang Y

OncoTargets and Therapy 2019, 12:11119-11129

Published Date: 17 December 2019

Original Research

CDK4/6 Inhibitor Palbociclib Amplifies the Radiosensitivity to Nasopharyngeal Carcinoma Cells via Mediating Apoptosis and Suppressing DNA Damage Repair

Xie X, Zheng W, Chen T, Lin W, Liao Z, Liu J, Ding Y

OncoTargets and Therapy 2019, 12:11107-11117

Published Date: 16 December 2019

Original Research

miR-7 Reverses Breast Cancer Resistance To Chemotherapy By Targeting MRP1 And BCL2

Hong T, Ding J, Li W

OncoTargets and Therapy 2019, 12:11097-11105

Published Date: 16 December 2019

Original Research

Extrapancreatic Neuropathy Correlates with Early Liver Metastasis in Pancreatic Head Adenocarcinoma

Lu M, Xiu D, Guo L, Yuan C, Zhang L, Tao L

OncoTargets and Therapy 2019, 12:11083-11095

Published Date: 16 December 2019

Review

miR-451: A Novel Biomarker and Potential Therapeutic Target for Cancer

Bai H, Wu S

OncoTargets and Therapy 2019, 12:11069-11082

Published Date: 16 December 2019

Original Research

Knockdown Of lncRNA NCK-AS1 Regulates Cisplatin Resistance Through Modulating miR-137 In Osteosarcoma Cells

Cheng Y, Shen X, Zheng M, Zou G, Shen Y

OncoTargets and Therapy 2019, 12:11057-11068

Published Date: 16 December 2019

Original Research

Oncogenic Role and Prognostic Value of MicroRNA-937-3p in Patients with Breast Cancer

Li D, Zhong J, Zhang G, Lin L, Liu Z

OncoTargets and Therapy 2019, 12:11045-11056

Published Date: 13 December 2019

Review

Cancer Immunotherapies Targeting Tumor-Associated Regulatory T Cells

Ge X, Zhao Y, Chen C, Wang J, Sun L

OncoTargets and Therapy 2019, 12:11033-11044

Published Date: 13 December 2019

Original Research

The Down-Regulation of lncRNA PCAT18 Promotes the Progression of Gastric Cancer via MiR-107/PTEN/PI3K/AKT Signaling Pathway

Chen P, Zhao X, Wang H, Zheng M, Wang Q, Chang W

OncoTargets and Therapy 2019, 12:11017-11031

Published Date: 13 December 2019

Original Research

LncRNA HOTAIRM1/HOXA1 Axis Promotes Cell Proliferation, Migration And Invasion In Endometrial Cancer

Li X, Pang L, Yang Z, Liu J, Li W, Wang D

OncoTargets and Therapy 2019, 12:10997-11015

Published Date: 13 December 2019

Case report

Durable Molecular Remission in a Lymphoid BP-CML Patient Harboring T315I Mutation Treated with Anti-CD19 CAR-T Therapy

Zhou L, Shi H, Shi W, Yang L, Zhang Y, Xu M, Chen X, Zhu Y, Mu H, Wan X, Yang Z, Zeng Y, Liu H

OncoTargets and Therapy 2019, 12:10989-10995

Published Date: 13 December 2019

Original Research

miR-449a Is Related to Short-Term Recurrence of Hepatocellular Carcinoma and Inhibits Migration and Invasion by Targeting Notch1

Han B, Huang J, Yang Z, Zhang J, Wang X, Xu N, Meng H, Wu J, Huang Q, Yang X, Shen R, Sun C

OncoTargets and Therapy 2019, 12:10975-10987

Published Date: 13 December 2019

Original Research

Long Non-Coding RNA BCAR4 Promotes Growth, Invasion and Tumorigenicity by Targeting miR-2276 to Upregulate MMP7 Expression in Glioma

Wang Z, Wang L, Liang Z, Xi Y

OncoTargets and Therapy 2019, 12:10963-10973

Published Date: 12 December 2019

Original Research

LncRNA RP11-422N16.3 Inhibits Cell Proliferation and EMT, and Induces Apoptosis in Hepatocellular Carcinoma Cells by Sponging miR-23b-3p

Sun Y, Zhou Q, Li J, Zhao C, Yu Z, Zhu Q

OncoTargets and Therapy 2019, 12:10943-10961

Published Date: 12 December 2019

Original Research

PRKD2 Promotes Progression and Chemoresistance of AML via Regulating Notch1 Pathway

Liu Q, Li W, Zhou Y, Jian J, Han S, Liu C, Li W, Zhu X, Ma D, Ji M, Ji C

OncoTargets and Therapy 2019, 12:10931-10941

Published Date: 12 December 2019

Original Research

Triterpenoid Saponins from Anemone flaccida Suppress Tumor Cell Proliferation by Regulating MAPK, PD1/PDL1, and STAT3 Signaling Pathways and Altering Cancer Metabolism

Han L, Yao S, Cao S, Mo G, Li J, Cao Y, Huang F

OncoTargets and Therapy 2019, 12:10917-10930

Published Date: 12 December 2019

Review

DNA Methyltransferase Inhibitors: Catalysts For Antitumour Immune Responses

Dan H, Zhang S, Zhou Y, Guan Q

OncoTargets and Therapy 2019, 12:10903-10916

Published Date: 12 December 2019

Case report

Response to Afatinib in a Patient with Non-Small Cell Lung Cancer Harboring HER2 R896G Mutation: A Case Report

Lin L, Ge H, Yan Z, Wang G, Wu X, Lv D

OncoTargets and Therapy 2019, 12:10897-10902

Published Date: 12 December 2019

Original Research

20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis

Phi LTH, Wijaya YT, Sari IN, Kim KS, Yang YG, Lee MW, Kwon HY

OncoTargets and Therapy 2019, 12:10885-10895

Published Date: 11 December 2019

Original Research

miR-181a Upregulation Promotes Radioresistance of Nasopharyngeal Carcinoma by Targeting RKIP

Huang W, Liu J, Hu S, Shi G, Yong Z, Li J, Qiu J, Cao Y, Yuan L

OncoTargets and Therapy 2019, 12:10873-10884

Published Date: 11 December 2019

Original Research

Knockdown of lncRNA TDRG1 Inhibits Tumorigenesis in Endometrial Carcinoma Through the PI3K/AKT/mTOR Pathway

Sun R, Sun X, Liu H, Li P

OncoTargets and Therapy 2019, 12:10863-10872

Published Date: 11 December 2019

Original Research

Knockdown of lncRNA HOXA-AS2 Inhibits Viability, Migration and Invasion of Osteosarcoma Cells by miR-124-3p/E2F3

Wang L, Wang L, Zhang X

OncoTargets and Therapy 2019, 12:10851-10861

Published Date: 11 December 2019

Original Research

Biological Functions of TNKS1 and Its Relationship with Wnt/β-Catenin Pathway in Astrocytoma

Chen M, Tang B, Xie S, Yan J, Yang L, Zhou X, Zeng E

OncoTargets and Therapy 2019, 12:10841-10850

Published Date: 11 December 2019

Original Research

Exosomes-Derived Long Non-Coding RNA HOTAIR Reduces Laryngeal Cancer Radiosensitivity by Regulating microRNA-454-3p/E2F2 Axis

Cui X, Xiao D, Cui Y, Wang X

OncoTargets and Therapy 2019, 12:10827-10839

Published Date: 11 December 2019

Original Research

Camellia nitidissima Chi Extract Potentiates the Sensitivity of Gastric Cancer Cells to Paclitaxel via the Induction of Autophagy and Apoptosis

He X, Li H, Zhan M, Li H, Jia A, Lin S, Sun L, Du H, Yuan S, Li Y

OncoTargets and Therapy 2019, 12:10811-10825

Published Date: 11 December 2019

Original Research

MicroRNA-145 Inhibits Cell Migration and Invasion in Colorectal Cancer by Targeting TWIST

Shen X, Jiang H, Chen Z, Lu B, Zhu Y, Mao J, Chai K, Chen W

OncoTargets and Therapy 2019, 12:10799-10809

Published Date: 10 December 2019

Original Research

Long Noncoding RNA KCNQ1OT1 Promotes the Progression of Non-Small Cell Lung Cancer via Regulating miR-204-5p/ATG3 Axis

Kang Y, Jia Y, Wang Q, Zhao Q, Song M, Ni R, Wang J

OncoTargets and Therapy 2019, 12:10787-10797

Published Date: 10 December 2019

Original Research

Knockdown of SLC35F2 Inhibits the Proliferation and Metastasis of Bladder Cancer Cells

Chen M, Gao X, Huang D, Wang S, Zheng L, Chen Y, Wen X, Gao Y, Cao H, Zhang S

OncoTargets and Therapy 2019, 12:10771-10786

Published Date: 10 December 2019

Case report

Low-Grade Chondrosarcoma In The Sellar Area: Case Report And Literature Review

Zhang Z, Pang LJ, Wang N, Li Z, Cao YW, Hu WH, Liang WH, Jiang JF, Zou H, Qi Y

OncoTargets and Therapy 2019, 12:10763-10770

Published Date: 10 December 2019

Original Research

Baicalein, as a Prooxidant, Triggers Mitochondrial Apoptosis in MCF-7 Human Breast Cancer Cells Through Mobilization of Intracellular Copper and Reactive Oxygen Species Generation

Liu ZH, Yang CX, Zhang L, Yang CY, Xu XQ

OncoTargets and Therapy 2019, 12:10749-10761

Published Date: 9 December 2019

Original Research

Low Expression of ASK1-Interacting Protein-1 Is Significantly Correlated with Tumor Angiogenesis and Poor Survival in Patients with Early Stage Non-Small Cell Lung Cancer

Chen C, Geng Q, Sun D, Hu W, Zhong C, Fan L, Song X

OncoTargets and Therapy 2019, 12:10739-10747

Published Date: 10 December 2019

Original Research

miR-139 Controls Viability Of Ovarian Cancer Cells Through Apoptosis Induction And Exosome Shedding Inhibition By Targeting ATP7A

Xiao F, Xiao S, Xue M

OncoTargets and Therapy 2019, 12:10727-10737

Published Date: 6 December 2019

Original Research

Long Noncoding RNA RP5-833A20.1 Suppresses Tumorigenesis In Hepatocellular Carcinoma Through Akt/ERK Pathway By Targeting miR-18a-5p

Chen Z, Ma Y, Pan Y, Zuo S, Zhu H, Yu C, Zhu C, Sun C

OncoTargets and Therapy 2019, 12:10717-10726

Published Date: 6 December 2019

Original Research

NRAS Contributes to Retinoblastoma Progression Through SNHG16/miR-183-5p/NRAS Regulatory Network

Sun G, Su G, Liu F, Han W

OncoTargets and Therapy 2019, 12:10703-10715

Published Date: 6 December 2019

Original Research

TRIM44 Promotes Colorectal Cancer Proliferation, Migration, and Invasion Through the Akt/mTOR Signaling Pathway

Li C, Hu H, Yang X, Huang C, Yu X

OncoTargets and Therapy 2019, 12:10693-10701

Published Date: 9 December 2019

Original Research

Long Noncoding RNA LINC00265 Targets EGFR and Promotes Deterioration of Colorectal Cancer: A Comprehensive Study Based on Data Mining and in vitro Validation

Ge H, Yan Y, Yue C, Liang C, Wu J

OncoTargets and Therapy 2019, 12:10681-10692

Published Date: 5 December 2019

Original Research

Long Non-Coding RNA HULC Promotes the Development of Breast Cancer Through Regulating LYPD1 Expression by Sponging miR-6754-5p

Wang N, Zhong C, Fu M, Li L, Wang F, Lv P, Zhu M, Xiong Y, Mi H, Gu Y

OncoTargets and Therapy 2019, 12:10671-10679

Published Date: 5 December 2019

Original Research

Cobalt Chloride Induced Apoptosis by Inhibiting GPC3 Expression via the HIF-1α/c-Myc Axis in HepG2 Cells

Tong Y, Tong K, Zhu Q, Wu Y, Yang Y, Zhang J, Hu P, Yan S

OncoTargets and Therapy 2019, 12:10663-10670

Published Date: 5 December 2019

Original Research

13-[CH2CO-Cys-(Bzl)-OBzl]-Berberine: Exploring The Correlation Of Anti-Tumor Efficacy With ROS And Apoptosis Protein

Li G, Ren Y, Zhang X, Zhao S, Wang Y, Wu J, Peng S, Zhao M

OncoTargets and Therapy 2019, 12:10651-10662

Published Date: 5 December 2019

Original Research

Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway

Xu T, Zhang R, Dong M, Zhang Z, Li H, Zhan C, Li X

OncoTargets and Therapy 2019, 12:10639-10650

Published Date: 4 December 2019

Original Research

NEDD4 Negatively Regulates GITR via Ubiquitination in Immune Microenvironment of Melanoma

Guo Y, Yang L, Lei S, Tan W, Long J

OncoTargets and Therapy 2019, 12:10629-10637

Published Date: 4 December 2019

Original Research

Piwi-Interacting RNA1037 Enhances Chemoresistance and Motility in Human Oral Squamous Cell Carcinoma Cells

Li G, Wang X, Li C, Hu S, Niu Z, Sun Q, Sun M

OncoTargets and Therapy 2019, 12:10615-10627

Published Date: 4 December 2019

Review

Nucleic Acid Aptamer: A Novel Potential Diagnostic and Therapeutic Tool for Leukemia

Tan Y, Li Y, Tang F

OncoTargets and Therapy 2019, 12:10597-10613

Published Date: 4 December 2019

Original Research

A Retrospective Analysis: A Novel Index Predicts Survival and Risk-Stratification for Bone Destruction in 419 Newly Diagnosed Multiple Myelomas

Jin Y, Shang Y, Liu H, Ding L, Tong X, Tu H, Yuan G, Zhou F

OncoTargets and Therapy 2019, 12:10587-10596

Published Date: 3 December 2019

Original Research

Apatinib Plus Temozolomide for Recurrent Glioblastoma: An Uncontrolled, Open-Label Study

Wang Y, Meng X, Zhou S, Zhu Y, Xu J, Tao R

OncoTargets and Therapy 2019, 12:10579-10585

Published Date: 3 December 2019

Original Research

LINC00096 Promotes the Proliferation and Invasion by Sponging miR-383-5p and Regulating RBM3 Expression in Triple-Negative Breast Cancer

Tian Y, Xia S, Ma M, Zuo Y

OncoTargets and Therapy 2019, 12:10569-10578

Published Date: 2 December 2019

Original Research

Pseudo-Progression and the Neutrophil-to-Lymphocyte Ratio in Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors: A Case–Control Study

Kiriu T, Yamamoto M, Nagano T, Hazama D, Sekiya R, Katsurada M, Katsurada N, Tachihara M, Kobayashi K, Nishimura Y

OncoTargets and Therapy 2019, 12:10559-10568

Published Date: 2 December 2019

Original Research

Docosahexaenoic Acid Serving As Sensitizing Agents And Gefitinib Resistance Revertants In EGFR Targeting Treatment

Ding X, Ge L, Yan A, Ding Y, Tao J, Liu Q, Qiao C

OncoTargets and Therapy 2019, 12:10547-10558

Published Date: 2 December 2019

Original Research

MicroRNA-497-5p Induces Cell Cycle Arrest Of Cervical Cancer Cells In S Phase By Targeting CBX4

Chen Y, Du J, Wang Y, Shi H, Jiang Q, Wang Y, Zhang H, Wei Y, Xue W, Pu Z, Gao Y, Li D, Feng Y, Yan J, Zhang J

OncoTargets and Therapy 2019, 12:10535-10545

Published Date: 2 December 2019

Original Research

EPS8 is a Potential Oncogene in Glioblastoma

Yang G, Lu Y, Guan Q

OncoTargets and Therapy 2019, 12:10523-10534

Published Date: 2 December 2019

Original Research

miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2

Sun J, Niu L, Gao S, Yi X, Chen J

OncoTargets and Therapy 2019, 12:10515-10522

Published Date: 2 December 2019

Original Research

JAZF1 Suppresses Papillary Thyroid Carcinoma Cell Proliferation and Facilitates Apoptosis via Regulating TAK1/NF-κB Pathways

Huang L, Cai Y, Luo Y, Xiong D, Hou Z, Lv J, Zeng F, Yang Y, Cheng X

OncoTargets and Therapy 2019, 12:10501-10514

Published Date: 2 December 2019

Case report

Initial Therapy of Advanced Anaplastic Thyroid Cancer via Targeting VEGFR-2: A Case Report

Cheng L, Jiao Q, Jin Y, Fu H, Zhang H, Chen L

OncoTargets and Therapy 2019, 12:10495-10500

Published Date: 2 December 2019

Original Research

Further Study of Circulating Antibodies to P16, CD25 and FOXP3 in Hepatocellular Carcinoma

Wang J, Xu Y, Wang Y, Zhang X, Zhang G

OncoTargets and Therapy 2019, 12:10487-10493

Published Date: 2 December 2019

Original Research

Differential Expression And Effects Of Peroxiredoxin-6 On Drug Resistance And Cancer Stem Cell-Like Properties In Non-Small Cell Lung Cancer

Xu J, Su Q, Gao M, Liang Q, Li J, Chen X

OncoTargets and Therapy 2019, 12:10477-10486