Arroyo-Acevedo JL, Rojas-Armas JP, Herrera-Calderón O, Chávez-Asmat R, Justil-Guerrero HJ, Aguilar-Carranza C, Enciso-Roca E, Tinco-Jayo JA, Yuli-Posadas RÁ, Franco-Quino C, Chumpitaz-Cerrate V

OncoTargets and Therapy 2019, 12:6555-6562

Published Date: 15 August 2019

Original Research

The efficacy and safety of anlotinib treatment for advanced lung cancer

Shao L, Wang W, Song Z, Zhang Y

OncoTargets and Therapy 2019, 12:6549-6554

Published Date: 15 August 2019

Review

Second-generation EGFR and ErbB tyrosine kinase inhibitors as first-line treatments for non-small cell lung cancer

Wang S, Li J

OncoTargets and Therapy 2019, 12:6535-6548

Published Date: 15 August 2019

Original Research

Downregulated miR-585-3p promotes cell growth and proliferation in colon cancer by upregulating PSME3

Liu C, Yang J, Wu H, Li J

OncoTargets and Therapy 2019, 12:6525-6534

Published Date: 14 August 2019

Original Research

Efficacy of a new oncolytic adenovirus armed with IL-13 against oral carcinoma models

Zhang KL, Li RP, Zhang BP, Gao ST, Li B, Huang CJ, Cao R, Cheng JY, Xie XD, Yu ZH, Feng XY

OncoTargets and Therapy 2019, 12:6515-6523

Published Date: 14 August 2019

Original Research

miR520a-3p suppresses cell proliferation and metastasis by inhibiting the p65–NFκB pathway in glioblastoma

Zhang J, Hong B

OncoTargets and Therapy 2019, 12:6503-6513

Published Date: 14 August 2019

Case report

Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report

Shu Y, Wang A, Yi L, Xu X, Yang W

OncoTargets and Therapy 2019, 12:6497-6501

Published Date: 14 August 2019

Review

Chinese perspectives on clinical efficacy and safety of alectinib in patients with ALK-positive advanced non-small cell lung cancer

Yu H, Sun S, Hu X, Xia J, Wang J, Chen H

OncoTargets and Therapy 2019, 12:6481-6495

Published Date: 14 August 2019

Original Research

LINC00491 as a new molecular marker can promote the proliferation, migration and invasion of colon adenocarcinoma cells

Wan J, Deng D, Wang X, Wang X, Jiang S, Cui R

OncoTargets and Therapy 2019, 12:6471-6480

Published Date: 13 August 2019

Original Research

HIF1α/PD-L1 axis mediates hypoxia-induced cell apoptosis and tumor progression in follicular thyroid carcinoma

Zhou L, Cha G, Chen L, Yang C, Xu D, Ge M

OncoTargets and Therapy 2019, 12:6461-6470

Published Date: 13 August 2019

Original Research

Establishment of reference intervals for serum [−2]proPSA (p2PSA), %p2PSA and prostate health index in healthy men

Wu ZY, Yang C, Luo J, Deng SL, Wu B, Chen M

OncoTargets and Therapy 2019, 12:6453-6460

Published Date: 13 August 2019

Original Research

Bio-physic constraint model using spatial registration of delta 18F-fluorodeoxyglucose positron emission tomography/computed tomography images for predicting radiation pneumonitis in esophageal squamous cell carcinoma patients receiving neoadjuvant chemoradiation

Hou TC, Dai KY, Wu MC, Hua KL, Tai HC, Huang WC, Chen YJ

OncoTargets and Therapy 2019, 12:6439-6451

Published Date: 13 August 2019

Original Research

Microwave ablation compared with radiofrequency ablation for treatment of hepatocellular carcinoma and liver metastases: a systematic review and meta-analysis

Glassberg MB, Ghosh S, Clymer JW, Qadeer RA, Ferko NC, Sadeghirad B, Wright GWJ, Amaral JF

OncoTargets and Therapy 2019, 12:6407-6438

Published Date: 13 August 2019

Original Research

FAM163A, a positive regulator of ERK signaling pathway, interacts with 14-3-3β and promotes cell proliferation in squamous cell lung carcinoma

Liu N, Zhou H, Zhang X, Cai L, Li J, Zhao J, Liu Y, Wang L, Fan C, Li A, Miao Y

OncoTargets and Therapy 2019, 12:6393-6406

Published Date: 13 August 2019

Original Research

Dosimetric comparison of different algorithms in stereotactic body radiation therapy (SBRT) plan for non-small cell lung cancer (NSCLC)

Zhang J, Jiang D, Su H, Dai Z, Dai J, Liu H, Xie C, Yu H

OncoTargets and Therapy 2019, 12:6385-6391

Published Date: 12 August 2019

Original Research

tRNA-derived fragment tRF-03357 promotes cell proliferation, migration and invasion in high-grade serous ovarian cancer

Zhang M, Li F, Wang J, He W, Li Y, Li H, Wei Z, Cao Y

OncoTargets and Therapy 2019, 12:6371-6383

Published Date: 16 August 2019

Original Research

The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines

Wei Y, Liu P, Li Q, Du J, Chen Y, Wang Y, Shi H, Wang Y, Zhang H, Xue W, Gao Y, Li D, Feng Y, Yan J, Han J, Zhang J

OncoTargets and Therapy 2019, 12:6361-6370

Published Date: 12 August 2019

Original Research

CircLMNB1 promotes colorectal cancer by regulating cell proliferation, apoptosis and epithelial-mesenchymal transition

He C, Huang C, Zhou R, Yu H

OncoTargets and Therapy 2019, 12:6349-6359

Published Date: 9 August 2019

Original Research

Albumin exfoliated titanium disulfide nanosheet: a multifunctional nanoplatform for synergistic photothermal/radiation colon cancer therapy

Cao C, Zhang J, Yang C, Xiang L, Liu W

OncoTargets and Therapy 2019, 12:6337-6347

Published Date: 9 August 2019

Original Research

Long noncoding RNA HCP5 suppresses skin cutaneous melanoma development by regulating RARRES3 gene expression via sponging miR-12

Wei X, Gu X, Ma M, Lou C

OncoTargets and Therapy 2019, 12:6323-6335

Published Date: 12 August 2019

Original Research

Silencing of CARMA3 inhibits bladder cancer cell migration and invasion via deactivating β-catenin signaling pathway

Man X, Liu T, Jiang Y, Zhang Z, Zhu Y, Li Z, Kong C, He J

OncoTargets and Therapy 2019, 12:6309-6322

Published Date: 9 August 2019

Original Research

LncRNA-MALAT1 regulates proliferation and apoptosis of ovarian cancer cells by targeting miR-503-5p

Sun Q, Li Q, Xie F

OncoTargets and Therapy 2019, 12:6297-6307

Published Date: 9 August 2019

Original Research

Upregulation of hypoxia-inducible factor 1α mRNA expression was associated with poor prognosis in patients with hepatocellular carcinoma

Cheng W, Cheng Z, Yang Z, Xing D, Zhang M

OncoTargets and Therapy 2019, 12:6285-6296

Published Date: 9 August 2019

Original Research

Thermo-chemotherapy inhibits the proliferation and metastasis of gastric cancer cells via suppression of EIF5A2 expression

Ba MC, Ba Z, Cui SZ, Gong YF, Chen C, Lin KP, Wu YB, Tu YN

OncoTargets and Therapy 2019, 12:6275-6284

Published Date: 9 August 2019

Review

PIM-1 kinase: a potential biomarker of triple-negative breast cancer

Chen J, Tang G

OncoTargets and Therapy 2019, 12:6267-6273

Published Date: 8 August 2019

Original Research

Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing αⅤβ3 integrin/FAK/PI3K/Akt signaling activation

Chen Y, Chen L, Zhang JY, Chen ZY, Liu T, Zhang YY, Fu LY, Fan SQ, Zhang MQ, Gan S, Zhang N, Shen XC

OncoTargets and Therapy 2019, 12:6253-6265

Published Date: 8 August 2019

Original Research

Association of miRNA-499 rs3746444 A>G variants with adenocarcinoma of esophagogastric junction (AEG) risk and lymph node status

Tang W, Wang Y, Pan H, Qiu H, Chen S

OncoTargets and Therapy 2019, 12:6245-6252

Published Date: 8 August 2019

Original Research

Contribution of programmed cell death 6 genetic variations, gender, and smoking status to lung cancer

Shen TC, Chang WS, Hsia TC, Li HT, Chen WC, Tsai CW, Bau DT

OncoTargets and Therapy 2019, 12:6237-6244

Published Date: 9 August 2019

Case report

Whole-exome sequencing insights into pulmonary artery sarcoma mimicking pulmonary embolism: a case report and review

Wu Y, Huang J, Wang Q, Zhang M, Luo Y, Wang X, Zhu X, Liu H

OncoTargets and Therapy 2019, 12:6227-6235

Published Date: 7 August 2019

Original Research

miRNA-15a regulates the proliferation and apoptosis of papillary thyroid carcinoma via regulating AKT pathway

Jin J, Zhang J, Xue Y, Luo L, Wang S, Tian H

OncoTargets and Therapy 2019, 12:6217-6226

Published Date: 6 August 2019

Original Research

Macrophage-associated lncRNA ELMO1-AS1: a novel therapeutic target and prognostic biomarker for hepatocellular carcinoma

Luo T, Chen M, Zhao Y, Wang D, Liu J, Chen J, Luo H, Li L

OncoTargets and Therapy 2019, 12:6203-6216

Published Date: 6 August 2019

Original Research

WTAP is a prognostic marker of high-grade serous ovarian cancer and regulates the progression of ovarian cancer cells

Yu HL, Ma XD, Tong JF, Li JQ, Guan XJ, Yang JH

OncoTargets and Therapy 2019, 12:6191-6201

Published Date: 6 August 2019

Original Research

Circular RNA hsa_circ_0023404 promotes proliferation, migration and invasion in non-small cell lung cancer by regulating miR-217/ZEB1 axis

Liu C, Zhang Z, Qi D

OncoTargets and Therapy 2019, 12:6181-6189

Published Date: 5 August 2019

Original Research

TGF-β1 mediates lncRNA GAPLINC expression to promote the migration and invasion of non-small cell lung cancer

Zhao J, Wang C, Liu S, Su X, Ouyang A

OncoTargets and Therapy 2019, 12:6175-6180

Published Date: 2 August 2019

Original Research

Exploration of bladder cancer-associated methylated miRNAs by methylated DNA immunoprecipitation sequencing

Gao X, Zheng W, Ye L, Wen X, Wang S, Cao H, Liu X, Huang D, Wang F, Zhang S

OncoTargets and Therapy 2019, 12:6165-6174

Published Date: 1 August 2019

Case report

A rare case of acute promyelocytic leukemia with IRF2BP2-RARA fusion; and literature review

Liu Y, Xu F, Hu H, Wen J, Su J, Zhou Q, Qu W

OncoTargets and Therapy 2019, 12:6157-6163

Published Date: 2 August 2019

Original Research

Long noncoding RNA LINC00673 promotes the proliferation and metastasis of epithelial ovarian cancer by associating with opioid growth factor receptor

Zheng T, Qiu J, Li C, Lin X, Tang X, Hua K

OncoTargets and Therapy 2019, 12:6145-6156

Published Date: 5 August 2019

Original Research

miR-495-3p inhibits the cell proliferation, invasion and migration of osteosarcoma by targeting C1q/TNF-related protein 3

Zhao G, Zhang L, Qian D, Sun Y, Liu W

OncoTargets and Therapy 2019, 12:6133-6143

Published Date: 2 August 2019

Original Research

Antitumor effect of kurarinone and underlying mechanism in small cell lung carcinoma cells

Chung TW, Lin CC, Lin SC, Chan HL, Yang CC

OncoTargets and Therapy 2019, 12:6119-6131

Published Date: 5 August 2019

Original Research

lncRNA FOXD2-AS1 confers cisplatin resistance of non-small-cell lung cancer via regulation of miR185-5p–SIX1 axis

Ge P, Cao L, Yao YJ, Jing RJ, Wang W, Li HJ

OncoTargets and Therapy 2019, 12:6105-6117

Published Date: 30 July 2019

Original Research

MiR-203 acts as a radiosensitizer of gastric cancer cells by directly targeting ZEB1

Jiang Y, Jin S, Tan S, Shen Q, Xue Y

OncoTargets and Therapy 2019, 12:6093-6104

Published Date: 30 July 2019

Original Research

VE-822 mediated inhibition of ATR signaling sensitizes chondrosarcoma to cisplatin via reversion of the DNA damage response

Liang X, Yang Q, Wang W, Liu T, Hu J

OncoTargets and Therapy 2019, 12:6083-6092

Published Date: 30 July 2019

Original Research

A temperature-sensitive phase-change hydrogel of topotecan achieves a long-term sustained antitumor effect on retinoblastoma cells

Huo Y, Wang Q, Liu Y, Wang J, Li Q, Li Z, Dong Y, Huang Y, Wang L

OncoTargets and Therapy 2019, 12:6069-6082

Published Date: 30 July 2019

Original Research

EP3 receptor antagonist L798,106 reduces proliferation and migration of SK-BR-3 breast cancer cells

Hester A, Salzmann B, Rahmeh M, Kolben T, Czogalla B, Ditsch N, Mahner S, Jeschke U, Kolben TM

OncoTargets and Therapy 2019, 12:6053-6068

Published Date: 29 July 2019

Original Research

Frequency and clinical features of BRAF mutations among patients with stage III/IV lung adenocarcinoma without EGFR/ALK aberrations

Kim HC, Kang YR, Ji W, Kim YJ, Yoon S, Lee JC, Choi CM

OncoTargets and Therapy 2019, 12:6045-6052

Published Date: 26 July 2019

Original Research

EGCG overcomes gefitinib resistance by inhibiting autophagy and augmenting cell death through targeting ERK phosphorylation in NSCLC

Meng J, Chang C, Chen Y, Bi F, Ji C, Liu W

OncoTargets and Therapy 2019, 12:6033-6043

Published Date: 26 July 2019

Review

Immune checkpoint inhibitors in esophageal squamous cell carcinoma: progress and opportunities

Jiao R, Luo H, Xu W, Ge H

OncoTargets and Therapy 2019, 12:6023-6032

Published Date: 29 July 2019

Review

Role of OCT1 in hepatocellular carcinoma

Li J, Yang Z, Tuo B

OncoTargets and Therapy 2019, 12:6013-6022

Published Date: 25 July 2019

Original Research

The role of PEG3 in the occurrence and prognosis of colon cancer

Zhou T, Lin W, Zhu Q, Renaud H, Liu X, Li R, Tang C, Ma C, Rao T, Tan Z, Guo Y

OncoTargets and Therapy 2019, 12:6001-6012

Published Date: 25 July 2019

Original Research

LINC00958-MYC positive feedback loop modulates resistance of head and neck squamous cell carcinoma cells to chemo- and radiotherapy in vitro

Huang S, Zhan Z, Li L, Guo H, Yao Y, Feng M, Deng J, Xiong J

OncoTargets and Therapy 2019, 12:5989-6000

Published Date: 24 July 2019

Original Research

Identification of seven-gene signature for prediction of lung squamous cell carcinoma

Wang Z, Wang Z, Niu X, Liu J, Wang Z, Chen L, Qin B

OncoTargets and Therapy 2019, 12:5979-5988

Published Date: 24 July 2019

Original Research

MicroRNA-27a downregulates the expression of Hsp90 and enhances the radiosensitivity in esophageal squamous cell carcinoma

Wang X, An D, Liu X, Wang X, Li B

OncoTargets and Therapy 2019, 12:5967-5977

Published Date: 23 July 2019

Original Research

14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma

Peng X, Tu Y, Fu S, Xia Y, Ma C, Yang Y, Wu H, Liu Y, You P

OncoTargets and Therapy 2019, 12:5955-5965

Published Date: 30 July 2019

Original Research

Fasting blood glucose levels and prognosis in patients with non-small-cell lung cancer: a prospective cohort study in China

Yang JR, Chen GC, Xu JY, Ling CJ, Yu N, Yang J, Zeng DX, Gu MJ, Li DP, Zhang YS, Qin LQ

OncoTargets and Therapy 2019, 12:5947-5953

Published Date: 23 July 2019

Original Research

MicroRNA-132 inhibits migration, invasion and epithelial-mesenchymal transition via TGFβ1/Smad2 signaling pathway in human bladder cancer

Wei XC, Lv ZH

OncoTargets and Therapy 2019, 12:5937-5945

Published Date: 23 July 2019

Review

High Tiam1 expression predicts positive lymphatic metastasis and worse survival in patients with malignant solid tumors: a systematic review and meta-analysis

Yang C, Ma C, Li Y, Mo P, Yang Y

OncoTargets and Therapy 2019, 12:5925-5936

Published Date: 25 July 2019

Case report

A case of primary gastric diffuse large B-cell lymphoma occurring in chronic myeloid leukemia

Cai Z, Liu S, Zi J, Ma J, Ge Z

OncoTargets and Therapy 2019, 12:5917-5923

Published Date: 22 July 2019

Original Research

Estradiol promotes the progression of ER+ breast cancer through methylation-mediated RSK4 inactivation

Li Q, Gao H, Yang H, Wei W, Jiang Y

OncoTargets and Therapy 2019, 12:5907-5916

Published Date: 22 July 2019

Original Research

The prognostic significance of SHP2 and its binding protein Hook1 in non-small cell lung cancer

He L, Li Y, Huang X, Cheng H, Ke Y, Wang L

OncoTargets and Therapy 2019, 12:5897-5906

Published Date: 22 July 2019

Original Research

AEG-1 promotes the growth of gastric cancer through the upregulation of eIF4E expression

Wu S, Zhang Z, Wu D, Chen H, Qian X, Wang X, Huang W

OncoTargets and Therapy 2019, 12:5887-5895

Published Date: 22 July 2019

Original Research

The prognostic value of LINC01296 in pan-cancers and the molecular regulatory mechanism in hepatocellular carcinoma: a comprehensive study based on data mining, bioinformatics, and in vitro validation

Liang C, Zhang Y, Zhang Y, Li R, Wang Z, Wei Z, Guo J

OncoTargets and Therapy 2019, 12:5861-5885

Published Date: 19 July 2019

Original Research

Hsa_circ_0003998 may be used as a new biomarker for the diagnosis and prognosis of hepatocellular carcinoma

Qiao GL, Chen L, Jiang WH, Yang C, Yang CM, Song LN, Chen Y, Yan HL, Ma LJ

OncoTargets and Therapy 2019, 12:5849-5860

Published Date: 19 July 2019

Original Research

Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression

Liu L, Lei B, Wang L, Chang C, Yang H, Liu J, Huang G, Xie W

OncoTargets and Therapy 2019, 12:5835-5848

Published Date: 18 July 2019

Original Research

Verticillin A suppresses HGF-induced migration and invasion via repression of the c-Met/FAK/Src pathway in human gastric and cervical cancer cells

Lu J, Li X, Tu K, Guan Y, Fung KP, Liu F

OncoTargets and Therapy 2019, 12:5823-5833

Published Date: 26 July 2019

Review

Update on elotuzumab for the treatment of relapsed/refractory multiple myeloma: patients’ selection and perspective

Trudel S, Moreau P, Touzeau C

OncoTargets and Therapy 2019, 12:5813-5822

Published Date: 18 July 2019

Original Research

A retrospective six-patient series of apatinib for the treatment of persistent or recurrent carcinoma of the cervix

Chen C, Qin S, Li Z, Luo X, Zhang Y, Zhang J, Liu X

OncoTargets and Therapy 2019, 12:5805-5811

Published Date: 17 July 2019

Original Research

ASAP3 is a downstream target of HIF-1α and is critical for progression of lung adenocarcinoma

Zhang P, Sun J, Kai J, Peng Y, Liu X, Zhou F, Wu J

OncoTargets and Therapy 2019, 12:5793-5803

Published Date: 17 July 2019

Original Research

Retrospective analysis of sorafenib efficacy and safety in Chinese patients with high recurrence rate of post-hepatic carcinectomy

Wang D, Jia W, Wang Z, Wen T, Ding W, Xia F, Zhang L, Wu F, Peng T, Liu B, Zhou C, Zheng Q, Miao X, Peng J, Huang Z, Dou K

OncoTargets and Therapy 2019, 12:5779-5791

Published Date: 17 July 2019

Original Research

The LncRNA XIRP2-AS1 predicts favorable prognosis in colon cancer

Zhou F, Shen F, Zheng Z, Ruan J

OncoTargets and Therapy 2019, 12:5767-5778

Published Date: 17 July 2019

Original Research

Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling

Wang B, Shen C, Li Y, Zhang T, Huang H, Ren J, Hu Z, Xu J, Xu B

OncoTargets and Therapy 2019, 12:5751-5765

Published Date: 17 July 2019

Original Research

Sichong formula inhibits the proliferation and migration of human gastric cancer cells

Wang M, Tian Z, Zhu Y, Ding J, Li C, Zhou Y, Zhang Y

OncoTargets and Therapy 2019, 12:5741-5750

Published Date: 16 July 2019

Original Research

MiR-34c acts as a tumor suppressor in non-small cell lung cancer by inducing endoplasmic reticulum stress through targeting HMGB1

Tu L, Long X, Song W, Lv Z, Zeng H, Wang T, Liu X, Dong J, Xu P

OncoTargets and Therapy 2019, 12:5729-5739

Published Date: 16 July 2019

Original Research

Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition

Xia L, Lin J, Su J, Oyang L, Wang H, Tan S, Tang Y, Chen X, Liu W, Luo X, Tian Y, Liang J, Su Q, Liao Q, Zhou Y

OncoTargets and Therapy 2019, 12:5713-5728

Published Date: 16 July 2019

Original Research

Matrix metalloproteinase 2 contributes to aggressive phenotype, epithelial-mesenchymal transition and poor outcome in nasopharyngeal carcinoma

Li S, Luo W

OncoTargets and Therapy 2019, 12:5701-5711

Published Date: 17 July 2019

Original Research

miR-937 regulates the proliferation and apoptosis via targeting APAF1 in breast cancer

Fang H, Jiang W, Jing Z, Mu X, Xiong Z

OncoTargets and Therapy 2019, 12:5687-5699

Published Date: 17 July 2019

Case report

Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report

Ramaswamy R, Joshi N, Khan MA, Siddhara S

OncoTargets and Therapy 2019, 12:5679-5685

Published Date: 15 July 2019

Original Research

LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy

Chu C, Niu X, Ou X, Hu C

OncoTargets and Therapy 2019, 12:5661-5677

Published Date: 15 July 2019

Original Research

THAP7 promotes cell proliferation by regulating the G1/S phase transition via epigenetically silencing p21 in lung adenocarcinoma

Chen CP, Sang Y, Liu L, Feng ZQ, Liang Z, Pei X

OncoTargets and Therapy 2019, 12:5651-5660

Published Date: 12 July 2019

Corrigendum

LncRNA PVT1 promotes proliferation, invasion and epithelial–mesenchymal transition of renal cell carcinoma cells through downregulation of miR-16-5p [Corrigendum]

Ren Y, Huang W, Weng G, Cui P, Liang H, Li Y

OncoTargets and Therapy 2019, 12:5649-5650

Published Date: 12 July 2019

Original Research

MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2

Yu LX, Zhang BL, Yang MY, Liu H, Xiao CH, Zhang SG, Liu R

OncoTargets and Therapy 2019, 12:5639-5647

Published Date: 15 July 2019

Original Research

Decitabine enhances cytotoxic effect of T cells with an anti-CD19 chimeric antigen receptor in treatment of lymphoma

Li S, Xue L, Wang M, Qiang P, Xu H, Zhang X, Kang W, You F, Xu H, Wang Y, Liu X, Yang L, Wang X

OncoTargets and Therapy 2019, 12:5627-5638

Published Date: 12 July 2019

Original Research

LncRNA LINC00668 promotes the progression of breast cancer by inhibiting apoptosis and accelerating cell cycle

Qiu X, Dong J, Zhao Z, Li J, Cai X

OncoTargets and Therapy 2019, 12:5615-5625

Published Date: 11 July 2019

Case report

Endoscopic submucosal dissection of tracheal deep benign fibrous histiocytoma using hybrid knife

Ma J, Miao Y, Lin X, Wang Q, Wang W, Kang J, Hou G

OncoTargets and Therapy 2019, 12:5609-5613

Published Date: 11 July 2019

Original Research

miR-21: a promising biomarker for the early detection of colon cancer

Dehghan F, Boozarpour S, Torabizadeh Z, Alijanpour S

OncoTargets and Therapy 2019, 12:5601-5607

Published Date: 11 July 2019

Original Research

Malic enzyme 1 (ME1) is a potential oncogene in gastric cancer cells and is associated with poor survival of gastric cancer patients

Shi Y, Zhou S, Wang P, Guo Y, Xie B, Ding S

OncoTargets and Therapy 2019, 12:5589-5599

Published Date: 11 July 2019

Original Research

Research on the establishment of a TPM3 monoclonal stable transfected PANC-1 cell line and the experiment of the EMT occurrence in human pancreatic cancer

Zhou S, Ma X, Wang ZJ, Zhang WY, Jiang H, Li SD, Zhang TZ, Du J, Lu Z

OncoTargets and Therapy 2019, 12:5577-5587

Published Date: 11 July 2019

Original Research

MicroRNA-652 suppresses malignant phenotypes in glioblastoma multiforme via FOXK1-mediated AKT/mTOR signaling pathway

Yang H, Song Z, Wu X, Wu Y, Liu C

OncoTargets and Therapy 2019, 12:5563-5575

Published Date: 10 July 2019

Original Research

12-Lipoxygenase promotes epithelial–mesenchymal transition via the Wnt/β-catenin signaling pathway in gastric cancer cells

Yang XH, Zhuang MK, Xie WH, Du F, Huang YH, Chen ZX, Chen FL, Wang XZ

OncoTargets and Therapy 2019, 12:5551-5561

Published Date: 11 July 2019

Case report

Successful treatment with osimertinib and its subsequent resistance mechanism in a patient with non-small-cell lung cancer harboring acquired EGFR T790M mutation after recovery from AC0010-induced interstitial lung disease

Wang H, Zhang L, Shi X, Zhang X, Si X

OncoTargets and Therapy 2019, 12:5545-5549

Published Date: 10 July 2019

Original Research

Tumor suppressive functions of LZTFL1 in hepatocellular carcinoma

Li S, Li J, Yu Z

OncoTargets and Therapy 2019, 12:5537-5544

Published Date: 10 July 2019

Original Research

Synergistic effect of meta-tetra(hydroxyphenyl)chlorin-based photodynamic therapy followed by cisplatin on malignant Hep-2 cells

Xue K, Wang YN, Zhao X, Zhang HX, Yu D, Jin CS

OncoTargets and Therapy 2019, 12:5525-5536

Published Date: 10 July 2019

Original Research

The total flavonoid of Eucommia ulmoides sensitizes human glioblastoma cells to radiotherapy via HIF-α/MMP-2 pathway and activates intrinsic apoptosis pathway

Wang Y, Tan X, Li S, Yang S

OncoTargets and Therapy 2019, 12:5515-5524

Published Date: 11 July 2019

Original Research

G protein-coupled receptor kinase 2 regulating β2-adrenergic receptor signaling in M2-polarized macrophages contributes to hepatocellular carcinoma progression

Wu JJ, Yang Y, Peng WT, Sun JC, Sun WY, Wei W

OncoTargets and Therapy 2019, 12:5499-5513

Published Date: 11 July 2019

Original Research

Long noncoding RNA DANCR contributes to docetaxel resistance in prostate cancer through targeting the miR-34a-5p/JAG1 pathway

Ma Y, Fan B, Ren Z, Liu B, Wang Y

OncoTargets and Therapy 2019, 12:5485-5497

Published Date: 9 July 2019

Review

Comparative review of drug–drug interactions with epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer

Xu ZY, Li JL

OncoTargets and Therapy 2019, 12:5467-5484

Published Date: 9 July 2019

Review

Progressive study of effects of erianin on anticancer activity

Zhang Y, Zhang Q, Wei F, Liu N

OncoTargets and Therapy 2019, 12:5457-5465

Published Date: 9 July 2019

Case report

t(15; 17) associated with primary myelofibrosis: a case report of an unusual clinical presentation and diagnostic dilemma

Nadiminti K, Silverman M, Bhagavathi S, Vikas P

OncoTargets and Therapy 2019, 12:5449-5455

Published Date: 11 July 2019

Original Research

microRNA-605 directly targets SOX9 to alleviate the aggressive phenotypes of glioblastoma multiforme cell lines by deactivating the PI3K/Akt pathway

Jia J, Wang J, Yin M, Liu Y

OncoTargets and Therapy 2019, 12:5437-5448

Published Date: 8 July 2019

Original Research

GLUT5 increases fructose utilization in ovarian cancer

Jin C, Gong X, Shang Y

OncoTargets and Therapy 2019, 12:5425-5436

Published Date: 8 July 2019

Original Research

Dual PI3K/mTOR Inhibitor, XL765, suppresses glioblastoma growth by inducing ER stress-dependent apoptosis

Zhao H, Chen G, Liang H

OncoTargets and Therapy 2019, 12:5415-5424

Published Date: 8 July 2019

Original Research

Long noncoding RNA DLEU1 aggravates glioma progression via the miR-421/MEF2D axis

Feng L, He M, Rao M, Diao J, Zhu Y

OncoTargets and Therapy 2019, 12:5405-5414

Published Date: 8 July 2019

Original Research

Identification and functional characterization of Lys-trimethylation of lactate dehydrogenase A

Li L, Zhao Z, Jiang W, Guo J, Zhang S

OncoTargets and Therapy 2019, 12:5395-5404

Published Date: 8 July 2019

Case report

Significant benefit of nivolumab combining radiotherapy in metastatic gallbladder cancer patient with strong PD-L1 expression: a case report

Kong W, Wei J, Liu J, Qiu Y, Shi J, He J, Su M, Xiao M, Liu B

OncoTargets and Therapy 2019, 12:5389-5393

Published Date: 8 July 2019

Original Research

Lycorine exerts antitumor activity against osteosarcoma cells in vitro and in vivo xenograft model through the JAK2/STAT3 pathway

Hu H, Wang S, Shi D, Zhong B, Huang X, Shi C, Shao Z

OncoTargets and Therapy 2019, 12:5377-5388

Published Date: 8 July 2019

Corrigendum

The role of IRAK1 in breast cancer patients treated with neoadjuvant chemotherapy [Corrigendum]

Yang M, Qin X, Qin G, Zheng X

OncoTargets and Therapy 2019, 12:5375-5376

Published Date: 5 July 2019

Original Research

The combination of the glycolysis inhibitor 2-DG and sorafenib can be effective against sorafenib-tolerant persister cancer cells

Wang L, Yang Q, Peng S, Liu X

OncoTargets and Therapy 2019, 12:5359-5373

Published Date: 8 July 2019

Case report

Successful long-term treatment of non–small cell lung cancer positive for RET rearrangement with pemetrexed

Takeda M, Sakai K, Nishio K, Nakagawa K

OncoTargets and Therapy 2019, 12:5355-5358

Published Date: 8 July 2019

Original Research

GATA1 gene silencing inhibits invasion, proliferation and migration of cholangiocarcinoma stem cells via disrupting the PI3K/AKT pathway

Shi G, Zhang H, Yu Q, Hu C, Ji Y

OncoTargets and Therapy 2019, 12:5335-5354

Published Date: 5 July 2019

Original Research

TGFβ1 is essential for MSCs-CAFs differentiation and promotes HCT116 cells migration and invasion via JAK/STAT3 signaling

Tan HX, Cao ZB, He TT, Huang T, Xiang CL, Liu Y

OncoTargets and Therapy 2019, 12:5323-5334

Published Date: 5 July 2019

Original Research

MicroRNA-936 targets FGF2 to inhibit epithelial ovarian cancer aggressiveness by deactivating the PI3K/Akt pathway

Li C, Yu S, Wu S, Ni Y, Pan Z

OncoTargets and Therapy 2019, 12:5311-5322

Published Date: 8 July 2019

Case report

Efficacy of afatinib in a HER2 amplification-positive endometrioid adenocarcinoma patient– a case report

Zhou L, Ren Y, Wang X, Miao D, Lizaso A, Li H, Han-Zhang H, Qian J, Yang H

OncoTargets and Therapy 2019, 12:5305-5309

Published Date: 4 July 2019

Case report

Stereotactic body radiotherapy as the initial treatment for hepatocellular carcinoma with extensive inferior vena cava and atrium tumor thrombus

Shui Y, Zhu X, Wu J, Liang T, Wei Q

OncoTargets and Therapy 2019, 12:5299-5303

Published Date: 4 July 2019

Case Series

Completely resolved advanced biliary tract cancer after treatment by pembrolizumab: a report of two cases

Alshari OM, Dawaymeh TA, Tashtush NA, Aleshawi AJ, Al Manasra ARA, Obeidat KA

OncoTargets and Therapy 2019, 12:5293-5298

Published Date: 4 July 2019

Original Research

Rhein sensitizes human colorectal cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

Zhuang Y, Bai Y, Hu Y, Guo Y, Xu L, Hu W, Yang L, Zhao C, Li X, Zhao H

OncoTargets and Therapy 2019, 12:5281-5291

Published Date: 3 July 2019

Original Research

Helicobacter pylori upregulates TRPC6 via Wnt/β-catenin signaling to promote gastric cancer migration and invasion

Song Y, Liu G, Liu S, Chen R, Wang N, Liu Z, Zhang X, Xiao Z, Liu L

OncoTargets and Therapy 2019, 12:5269-5279

Published Date: 3 July 2019

Review

Animal models of well-differentiated/dedifferentiated liposarcoma: utility and limitations

Codenotti S, Mansoury W, Pinardi L, Monti E, Marampon F, Fanzani A

OncoTargets and Therapy 2019, 12:5257-5268

Published Date: 3 July 2019

Case report

Effective high intensity focused ultrasound treatment in recurrent aggressive breast fibromatosis: a case report

Zhao J, Wang Q, Li X, Hu X, Shen H

OncoTargets and Therapy 2019, 12:5251-5256

Published Date: 2 July 2019

Original Research

Albumin-to-alkaline phosphatase ratio at diagnosis predicts survival in patients with metastatic non-small-cell lung cancer

Li D, Yu H, Li W

OncoTargets and Therapy 2019, 12:5241-5249

Published Date: 2 July 2019

Original Research

Ethyl acetate extracts of Nepenthes ventricosa x sibuyanensis leaves cause growth inhibition against oral cancer cells via oxidative stress

Tang JY, Yu TJ, Lin LC, Peng SY, Wang CL, Ou-Yang F, Cheng YB, Chang HW

OncoTargets and Therapy 2019, 12:5227-5239

Published Date: 3 July 2019

Original Research

LSD1 regulates Notch and PI3K/Akt/mTOR pathways through binding the promoter regions of Notch target genes in esophageal squamous cell carcinoma

Hou G, Zhao Q, Zhang M, Wang P, Ye H, Wang Y, Ren Y, Zhang J, Lu Z

OncoTargets and Therapy 2019, 12:5215-5225

Published Date: 2 July 2019

Original Research

Prognostic value of aspartate transaminase to alanine transaminase (De Ritis) ratio in solid tumors: a pooled analysis of 9,400 patients

Wu J, Chen L, Wang Y, Tan W, Huang Z

OncoTargets and Therapy 2019, 12:5201-5213

Published Date: 2 July 2019

Original Research

C-terminal of E1A binding protein 1 enhances the migration of gastric epithelial cells and has a clinicopathologic significance in human gastric carcinoma

Wang C, Wang M, Xing B, Chi Z, Wang H, Lie C, Dong H

OncoTargets and Therapy 2019, 12:5189-5200

Published Date: 2 July 2019

Review

Evidence to date: talazoparib in the treatment of breast cancer

Exman P, Barroso-Sousa R, Tolaney SM

OncoTargets and Therapy 2019, 12:5177-5187

Published Date: 2 July 2019

Original Research

Dehydrocorydaline inhibits cell proliferation, migration and invasion via suppressing MEK1/2-ERK1/2 cascade in melanoma

Hu H, Dong Z, Wang X, Bai L, Lei Q, Yang J, Li L, Li Q, Liu L, Zhang Y, Ji Y, Guo L, Liu Y, Cui H

OncoTargets and Therapy 2019, 12:5163-5175

Published Date: 2 July 2019

Original Research

Bioinformatics analysis of molecular genetic targets and key pathways for hepatocellular carcinoma

Tu J, Chen J, He M, Tong H, Liu H, Zhou B, Liao Y, Wang Z

OncoTargets and Therapy 2019, 12:5153-5162

Published Date: 2 July 2019

Original Research

MTSS1 inhibits metastatic potential and induces G2/M phase cell cycle arrest in gastric cancer

Liu K, Jiao XD, Hao JL, Qin BD, Wu Y, Chen W, Liu J, He X, Zang YS

OncoTargets and Therapy 2019, 12:5143-5152

Published Date: 2 July 2019

Original Research

The safety and efficacy of amrubicin in the treatment of previously untreated extensive-disease small-cell lung cancer: a meta-analysis

Wu JF, Zhou JJ, Li XA, Hu LH, Wen ML

OncoTargets and Therapy 2019, 12:5135-5142

Published Date: 1 July 2019

Review

Targeted therapy and personalized medicine in gastrointestinal stromal tumors: drug resistance, mechanisms, and treatment strategies

Li GZ, Raut CP

OncoTargets and Therapy 2019, 12:5123-5133

Published Date: 1 July 2019

Original Research

Dihydrotanshinone I inhibits the growth of osteosarcoma through the Wnt/β-catenin signaling pathway

Tan T, Chen J, Hu Y, Wang N, Chen Y, Yu T, Lin D, Yang S, Luo J, Luo X

OncoTargets and Therapy 2019, 12:5111-5122

Published Date: 2 July 2019

Review

Update on liquid biopsy in clinical management of non-small cell lung cancer

Wu Z, Yang Z, Dai Y, Zhu Q, Chen LA

OncoTargets and Therapy 2019, 12:5097-5109

Published Date: 1 July 2019

Original Research

Dietary natural astaxanthin at an early stage inhibits N-nitrosomethylbenzylamine–induced esophageal cancer oxidative stress and inflammation via downregulation of NFκB and COX2 in F344 rats

Cui L, Xu F, Wang M, Li L, Qiao T, Cui H, Li Z, Sun C

OncoTargets and Therapy 2019, 12:5087-5096

Published Date: 1 July 2019

Original Research

Preparation of highly activated natural killer cells for advanced lung cancer therapy

Xie S, Wu Z, Niu L, Chen J, Ma Y, Zhang M

OncoTargets and Therapy 2019, 12:5077-5086

Published Date: 1 July 2019

Original Research

Overexpression of miR-450 affects the biological behavior of HepG2 cells by targeting DNMT3a

Wang Y, Wang L, Yu X, Duan J

OncoTargets and Therapy 2019, 12:5069-5076

Published Date: 1 July 2019

Original Research

Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways

Wu J, Qu J, Cao H, Jing C, Wang Z, Xu H, Ma R

OncoTargets and Therapy 2019, 12:5053-5067

Published Date: 28 June 2019

Original Research

PRPF40A as a potential diagnostic and prognostic marker is upregulated in pancreatic cancer tissues and cell lines: an integrated bioinformatics data analysis

Huo Z, Zhai S, Weng Y, Qian H, Tang X, Shi Y, Deng X, Wang Y, Shen B

OncoTargets and Therapy 2019, 12:5037-5051

Published Date: 28 June 2019

Original Research

Cyclin-dependent kinase inhibitor 2B gene is associated with the sensitivity of hepatoma cells to Sorafenib

Weng X, Zeng L, Yan F, He M, Wu X, Zheng D

OncoTargets and Therapy 2019, 12:5025-5036

Published Date: 28 June 2019

Original Research

Clinical efficacy of decitabine in combination with standard-dose cytarabine, aclarubicin hydrochloride, and granulocyte colony-stimulating factor in the treatment of young patients with newly diagnosed acute myeloid leukemia

Dou L, Xu Q, Wang M, Xiao Y, Cheng L, Li H, Huang W, Mei J, Jing Y, Bo J, Liu D, Yu L

OncoTargets and Therapy 2019, 12:5013-5023

Published Date: 28 June 2019

Original Research

ARHGAP4 mediates the Warburg effect in pancreatic cancer through the mTOR and HIF-1α signaling pathways

Shen Y, Chen G, Zhuang L, Xu L, Lin J, Liu L

OncoTargets and Therapy 2019, 12:5003-5012

Published Date: 28 June 2019

Original Research

The role of miR-382-5p in glioma cell proliferation, migration and invasion

Wang J, Chen C, Yan X, Wang P

OncoTargets and Therapy 2019, 12:4993-5002

Published Date: 25 June 2019

Original Research

CXCR4 antagonism in combination with IDO1 inhibition weakens immune suppression and inhibits tumor growth in mouse breast cancer bone metastases

Zhang J, Pang Y, Xie T, Zhu L

OncoTargets and Therapy 2019, 12:4985-4992

Published Date: 28 June 2019

Original Research

TRIM11 promotes proliferation and glycolysis of breast cancer cells via targeting AKT/GLUT1 pathway

Song W, Wang Z, Gu X, Wang A, Chen X, Miao H, Chu J, Tian Y

OncoTargets and Therapy 2019, 12:4975-4984

Published Date: 28 June 2019

Review

A pooled meta-analysis of PD-1/L1 inhibitors incorporation therapy for advanced non-small cell lung cancer

Wan N, Ji B, Li J, Jiang J, Yang C, Zhang T, Huang W

OncoTargets and Therapy 2019, 12:4955-4973

Published Date: 27 June 2019

Review

Dissecting the prevention of estrogen-dependent breast carcinogenesis through Nrf2-dependent and independent mechanisms

Giudice A, Barbieri A, Bimonte S, Cascella M, Cuomo A, Crispo A, D'Arena G, Galdiero M, Della Pepa ME, Botti G, Caraglia M, Capunzo M, Arra C, Montella M

OncoTargets and Therapy 2019, 12:4937-4953

Published Date: 24 June 2019

Original Research

miR-373 promotes neuroblastoma cell proliferation, migration, and invasion by targeting SRCIN1

Yuan XL, Wen FQ, Chen XW, Jiang XP, Liu SX

OncoTargets and Therapy 2019, 12:4927-4936

Published Date: 21 June 2019

Original Research

IFN-γ and TNF-α aggravate endothelial damage caused by CD123-targeted CAR T cell

Sun Y, Wang S, Zhao L, Zhang B, Chen H

OncoTargets and Therapy 2019, 12:4907-4925

Published Date: 24 June 2019

Original Research

miR-3691-5p promotes hepatocellular carcinoma cell migration and invasion through activating PI3K/Akt signaling by targeting PTEN

Du W, Zhang X, Wan Z

OncoTargets and Therapy 2019, 12:4897-4906

Published Date: 21 June 2019

Original Research

Long noncoding RNA LINC01089 predicts clinical prognosis and inhibits cell proliferation and invasion through the Wnt/β-catenin signaling pathway in breast cancer

Yuan H, Qin Y, Zeng B, Feng Y, Li Y, Xiang T, Ren G

OncoTargets and Therapy 2019, 12:4883-4895

Published Date: 21 June 2019

Original Research

microRNA-564 inhibits the aggressive phenotypes of papillary thyroid cancer by directly targeting astrocyte-elevated gene-1

Song Z, Yang H, Wu X, Kong C, Xu C

OncoTargets and Therapy 2019, 12:4869-4881

Published Date: 28 June 2019

Review

Prolonged low-dose infusion for gemcitabine: a systematic review

Zhao D, Chen J, Chu M, Wang J

OncoTargets and Therapy 2019, 12:4859-4868

Published Date: 21 June 2019

Original Research

Retrospective study of the efficacy and toxicity of lobaplatin in combined chemotherapy for metastatic breast cancer

Wu Y, Xu XY, Yan F, Sun WL, Zhang Y, Liu DL, Shen B

OncoTargets and Therapy 2019, 12:4849-4857

Published Date: 21 June 2019

Original Research

Upregulation of microRNA-1270 suppressed human glioblastoma cancer cell proliferation migration and tumorigenesis by acting through WT1

Wei L, Li P, Zhao C, Wang N, Wei N

OncoTargets and Therapy 2019, 12:4839-4848

Published Date: 20 June 2019

Original Research

Abietic acid suppresses non-small-cell lung cancer cell growth via blocking IKKβ/NF-κB signaling

Liu X, Chen W, Liu Q, Dai J

OncoTargets and Therapy 2019, 12:4825-4837

Published Date: 20 June 2019

Original Research

MicroRNA-937 inhibits the malignant phenotypes of breast cancer by directly targeting and downregulating forkhead box Q1

Han X, Guo X, Zhang W, Cong Q

OncoTargets and Therapy 2019, 12:4813-4824

Published Date: 20 June 2019

Case report

BRAF V600E-positive monomorphic epitheliotropic intestinal T-cell lymphoma complicating the course of hairy cell leukemia

Broccoli A, Bertuzzi C, Fiorentino M, Morigi A, Stefoni V, Agostinelli C, Argnani L, Cavo M, Zinzani PL

OncoTargets and Therapy 2019, 12:4807-4812

Published Date: 20 June 2019

Original Research

Upregulated RACK1 attenuates gastric cancer cell growth and epithelial–mesenchymal transition via suppressing Wnt/β-catenin signaling

Zhu L, Chen W, Li G, Chen H, Liao W, Zhang L, Xiao X

OncoTargets and Therapy 2019, 12:4795-4805

Published Date: 20 June 2019

Original Research

SOX30 methylation correlates with disease progression in patients with chronic myeloid leukemia

Zhang TJ, Wen XM, Zhou JD, Gu Y, Xu ZJ, Guo H, Ma JC, Yuan Q, Chen Q, Lin J, Qian J

OncoTargets and Therapy 2019, 12:4789-4794

Published Date: 20 June 2019

Original Research

Downregulation of H19 decreases the radioresistance in esophageal squamous cell carcinoma cells

Luo W, Liu W, Yao J, Zhu W, Zhang H, Sheng Q, Wang L, Lv L, Qian L

OncoTargets and Therapy 2019, 12:4779-4788

Published Date: 19 June 2019

Review

Emerging roles of circular RNAs in colorectal cancer

Hao S, Cong L, Qu R, Liu R, Zhang G, Li Y

OncoTargets and Therapy 2019, 12:4765-4777

Published Date: 19 June 2019

Original Research

Decreased expression of SPINT1-AS1 and SPINT1 mRNA might be independent unfavorable prognostic indicators in esophageal squamous cell carcinoma

Shen FF, Pan Y, Yang HJ, Li JK, Zhao F, Su JF, Li YY, Tian LQ, Yu PT, Cao YT, Zhang YW, Zhou FY

OncoTargets and Therapy 2019, 12:4755-4763

Published Date: 20 June 2019

Original Research

Intramedullary spinal cord metastasis in malignancies: an institutional analysis and review

Lv J, Liu B, Quan X, Li C, Dong L, Liu M

OncoTargets and Therapy 2019, 12:4741-4753

Published Date: 21 June 2019

Original Research

Long noncoding RNA LINC-PINT promotes proliferation through EZH2 and predicts poor prognosis in clear cell renal cell carcinoma

Duan J, Ma X, Shi J, Xuan Y, Wang H, Li P, Zhang Y, Fan Y, Gong H, Ma X, Pang Y, Wang L, Yan Y, Zhang X

OncoTargets and Therapy 2019, 12:4729-4740

Published Date: 19 June 2019

Review

Oral microbiota and gastrointestinal cancer

Zhang Y, Niu Q, Fan W, Huang F, He H

OncoTargets and Therapy 2019, 12:4721-4728

Published Date: 18 June 2019

Original Research

Effect of the imatinib treatment regimen on the postoperative prognosis of patients with high-risk gastrointestinal stromal tumors

Li YS, Li W, Zeng QS, Fu WH

OncoTargets and Therapy 2019, 12:4713-4719

Published Date: 18 June 2019

Original Research

Overexpression of CD55 correlates with tumor progression and poor prognosis in gastric stromal tumors

Yin X, Shen C, Yin Y, Cai Z, Wang J, Zhao Z, Chen X, Chen Z, Chen H, Zhang B

OncoTargets and Therapy 2019, 12:4703-4712

Published Date: 18 June 2019

Original Research

Effects of BCc1 nanoparticle and its mixture with doxorubicin on survival of murine 4T1 tumor model

Hafizi M, Soleimani M, Noorian S, Kalanaky S, Fakharzadeh S, Tavakolpoor Saleh N, Nazaran MH, Akbari ME

OncoTargets and Therapy 2019, 12:4691-4701

Published Date: 18 June 2019

Original Research

WHSC1 acts as a prognostic indicator and functions as an oncogene in cervical cancer

Wu J, Luo M, Duan Z, Jia Y, Linghu H, Tian P, Qi H

OncoTargets and Therapy 2019, 12:4683-4690

Published Date: 17 June 2019

Original Research

Effect of overexpression of Oct4 and Sox2 genes on the biological and oncological characteristics of gastric cancer cells

Chen B, Zhu Z, Li L, Ye W, Zeng J, Gao J, Wang S, Zhang L, Huang Z

OncoTargets and Therapy 2019, 12:4667-4682

Published Date: 18 June 2019

Corrigendum

Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway [Corrigendum]

Zhang R, Yu Q, Lu W, Shen J, Zhou D, Wang Y, Gao S, Wang Z

OncoTargets and Therapy 2019, 12:4665-4666

Published Date: 14 June 2019

Original Research

Studies on the treatment of melanoma with folate acid conjugated dextran and lauryl alcohol loaded with IMD0354

Liu C, Chen W, Chen Z, Yan Y, Wang Q, Xie H, Chen X, Wang A, Tang S, Zhou J

OncoTargets and Therapy 2019, 12:4655-4663

Published Date: 14 June 2019

Original Research

Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression

Wang M, Xu Y, Wen GZ, Wang Q, Yuan SM

OncoTargets and Therapy 2019, 12:4643-4654

Published Date: 13 June 2019

Original Research

Association between potentially functional polymorphisms of chemokine family members and the survival of esophageal cancer patients in a Chinese population

Du JL, Li GN, He RW, Zhang SZ, Zhang X, Huang ZG

OncoTargets and Therapy 2019, 12:4631-4641

Published Date: 13 June 2019

Original Research

Overexpression of microRNA-216a inhibits autophagy by targeting regulated MAP1S in colorectal cancer

Wang Y, Zhang S, Dang S, Fang X, Liu M

OncoTargets and Therapy 2019, 12:4621-4629

Published Date: 12 June 2019

Review

Immune checkpoint inhibitors for small cell lung cancer: opportunities and challenges

Regzedmaa O, Zhang H, Liu H, Chen J

OncoTargets and Therapy 2019, 12:4605-4620

Published Date: 13 June 2019

Original Research

Downregulation of microRNA-4324 promotes the EMT of esophageal squamous-cell carcinoma cells via upregulating FAK

Zhou J, Zhu J, Jiang G, Feng J, Wang Q

OncoTargets and Therapy 2019, 12:4595-4604

Published Date: 12 June 2019

Original Research

Harmine suppresses the proliferation of pancreatic cancer cells and sensitizes pancreatic cancer to gemcitabine treatment

Wu LW, Zhang JK, Rao M, Zhang ZY, Zhu HJ, Zhang C

OncoTargets and Therapy 2019, 12:4585-4593

Published Date: 12 June 2019

Case report

Probe-based confocal laser endomicroscopy (pCLE) is a suitable method for extrapulmonary high grade neuroendocrine rectal carcinoma (HGNEC) evaluation

Cannizzaro R, Maiero S, Fornasarig M, Canzonieri V, Magris R, Guarnieri G, Urbani M, Buonadonna A, Baresic T, Spessotto P

OncoTargets and Therapy 2019, 12:4577-4583

Published Date: 17 June 2019

Review

Profile of alectinib for the treatment of ALK-positive non-small cell lung cancer (NSCLC): patient selection and perspectives

Karachaliou N, Fernandez Bruno M, Bracht JWP, Rosell R

OncoTargets and Therapy 2019, 12:4567-4575

Published Date: 13 June 2019

Original Research

Pseudogene DUXAP10 acts as a diagnostic and prognostic marker and promotes cell proliferation by activating PI3K/AKT pathway in hepatocellular carcinoma

Yue C, Liang C, Ge H, Yan L, Xu Y, Li G, Li P, Wei Z, Wu J

OncoTargets and Therapy 2019, 12:4555-4566

Published Date: 11 June 2019

Review

Evaluating tisagenlecleucel and its potential in the treatment of relapsed or refractory diffuse large B cell lymphoma: evidence to date

Zavras PD, Wang Y, Gandhi A, Lontos K, Delgoffe GM

OncoTargets and Therapy 2019, 12:4543-4554

Published Date: 11 June 2019

Original Research

KIF5B-RET fusion gene and its correlation with clinicopathological and prognosis features in lung cancer: a meta-analysis

Cong XF, Yang L, Chen C, Liu Z

OncoTargets and Therapy 2019, 12:4533-4542

Published Date: 11 June 2019

Original Research

Identification of candidate biomarkers correlated with the diagnosis and prognosis of cervical cancer via integrated bioinformatics analysis

Dai F, Chen G, Wang Y, Zhang L, Long Y, Yuan M, Yang D, Liu S, Cheng Y, Zhang L

OncoTargets and Therapy 2019, 12:4517-4532

Published Date: 12 June 2019

Original Research

MiRNA-124 inhibits the proliferation, migration and invasion of cancer cell in hepatocellular carcinoma by downregulating lncRNA-UCA1

Zhao B, Lu Y, Cao X, Zhu W, Kong L, Ji H, Zhang F, Lin X, Guan Q, Ou K, Zhang X, Chen Q

OncoTargets and Therapy 2019, 12:4509-4516

Published Date: 12 June 2019

Original Research

Ilex hainanensis Merr targets ITGAV to suppress the proliferation and metastasis of osteosarcoma cells

Pei Y, Zhang YY, Zheng K, Shang GN, Wang YM, Wang W, Qiu ED, Li SL, Liu F, Zhang XJ

OncoTargets and Therapy 2019, 12:4499-4507

Published Date: 7 June 2019

Original Research

A pooled analysis of transarterial radioembolization with yttrium-90 microspheres for the treatment of unresectable intrahepatic cholangiocarcinoma

Zhen Y, Liu B, Chang Z, Ren H, Liu Z, Zheng J

OncoTargets and Therapy 2019, 12:4489-4498

Published Date: 7 June 2019

Original Research

LINC00339 promotes growth and invasiveness of hepatocellular carcinoma by the miR-1182/SKA1 pathway

Xiao J, Yu H, Ma Z

OncoTargets and Therapy 2019, 12:4481-4488

Published Date: 6 June 2019

Original Research

Long non-coding RNA FLJ33360 participates in ovarian cancer progression by sponging miR-30b-3p

Yang M, Zhai Z, Guo S, Li X, Zhu Y, Wang Y

OncoTargets and Therapy 2019, 12:4469-4480

Published Date: 7 June 2019

Original Research

The natural flavonoid glycoside vitexin displays preclinical antitumor activity by suppressing NF-κB signaling in nasopharyngeal carcinoma

Wang W, Cheng H, Gu X, Yin X

OncoTargets and Therapy 2019, 12:4461-4468

Published Date: 5 June 2019

Original Research

Androgen upregulates the palmitoylation of eIF3L in human prostate LNCaP cells

Cui L, Liu M, Lai S, Hou H, Diao T, Zhang D, Wang M, Zhang Y, Wang J

OncoTargets and Therapy 2019, 12:4451-4459

Published Date: 5 June 2019

Original Research

Sphingosine kinase 2 inhibitor ABC294640 displays anti-epithelial ovarian cancer activities in vitro and in vivo

Song K, Dai L, Long X, Cui X, Liu Y, Di W

OncoTargets and Therapy 2019, 12:4437-4449

Published Date: 6 June 2019

Original Research

Licochalcone A inhibits cell proliferation, migration, and invasion through regulating the PI3K/AKT signaling pathway in oral squamous cell carcinoma

Hao Y, Zhang C, Sun Y, Xu H

OncoTargets and Therapy 2019, 12:4427-4435

Published Date: 5 June 2019

Original Research

MicroRNA-559 plays an inhibitory role in the malignant progression of glioblastoma cells by directly targeting metadherin

Yang F, Zhang C, Xu C, Fu F, Han D, Li H

OncoTargets and Therapy 2019, 12:4415-4426

Published Date: 5 June 2019

Original Research

Norcantharidin inhibits the DDR of bladder cancer stem-like cells through cdc6 degradation

Shi X, Chen S, Zhang Y, Xie W, Hu Z, Li H, Li J, Zhou Z, Tan W

OncoTargets and Therapy 2019, 12:4403-4413

Published Date: 7 June 2019

Original Research

m6A methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways

Deng R, Cheng Y, Ye S, Zhang J, Huang R, Li P, Liu H, Deng Q, Wu X, Lan P, Deng Y

OncoTargets and Therapy 2019, 12:4391-4402

Published Date: 4 June 2019

Original Research

High expression of GMⅡ is associated with poor prognosis of gastric cancer patients

Zhu S, Li Y, Xiao W, Yang Y

OncoTargets and Therapy 2019, 12:4379-4389

Published Date: 4 June 2019

Original Research

Deferoxamine-induced high expression of TfR1 and DMT1 enhanced iron uptake in triple-negative breast cancer cells by activating IL-6/PI3K/AKT pathway

Chen C, Liu P, Duan X, Cheng M, Xu LX

OncoTargets and Therapy 2019, 12:4359-4377

Published Date: 31 May 2019

Original Research

Diagnostic and prognostic roles of circ-SHPRH for solid cancers: a meta-analysis

Li F, Huang Q, Gong Z, Wang H, Chen J

OncoTargets and Therapy 2019, 12:4351-4357

Published Date: 31 May 2019

Original Research

Knockdown of cyclooxygenase-2 leads to growth inhibition and cell cycle arrest in hepatocellular carcinoma cells

Lv X, Chen Z, Li S, Xie H

OncoTargets and Therapy 2019, 12:4341-4349

Published Date: 31 May 2019

Original Research

Long intergenic noncoding RNA 00707 promotes colorectal cancer cell proliferation and metastasis by sponging miR-206

Zhu H, He G, Wang Y, Hu Y, Zhang Z, Qian X, Wang Y

OncoTargets and Therapy 2019, 12:4331-4340

Published Date: 31 May 2019

Original Research

Zoledronic acid exhibits radio-sensitizing activity in human pancreatic cancer cells via inactivation of STAT3/NF-κB signaling

You Y, Wang Q, Li H, Ma Y, Deng Y, Ye Z, Bai F

OncoTargets and Therapy 2019, 12:4323-4330

Published Date: 4 June 2019

Retraction

Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway [Retraction]

Jin Y-L, Xin L-M, Zhou C-C, Ren Y

OncoTargets and Therapy 2019, 12:4321-4322

Published Date: 4 June 2019

Original Research

Variability within the human TERT gene, telomere length and predisposition to chronic lymphocytic leukemia

Wysoczanska B, Dratwa M, Gebura K, Mizgala J, Mazur G, Wrobel T, Bogunia-Kubik K

OncoTargets and Therapy 2019, 12:4309-4320

Published Date: 31 May 2019

Original Research

SKP2 targeted inhibition suppresses human uveal melanoma progression by blocking ubiquitylation of p27

Zhao H, Pan H, Wang H, Chai P, Ge S, Jia R, Fan X

OncoTargets and Therapy 2019, 12:4297-4308

Published Date: 30 May 2019

Original Research

LncRNA FENDRR attenuates colon cancer progression by repression of SOX4 protein

Liu J, Du W

OncoTargets and Therapy 2019, 12:4287-4295

Published Date: 30 May 2019

Case report

Diagnosis and treatment of synchronous multiple primary lung cancer – a case report

Bao Y, Wu J, Zhang J, Yu Y

OncoTargets and Therapy 2019, 12:4281-4285

Published Date: 29 May 2019

Original Research

HnRNPL promotes Wilms tumor progression by regulating the p53 and Bcl2 pathways

Luo X, Deng C, Liu F, Liu X, Lin T, He D, Wei G

OncoTargets and Therapy 2019, 12:4269-4279

Published Date: 29 May 2019

Case report

Complete response to crizotinib in a metastatic adenocarcinoma of unknown primary harboring MET amplification and NTRK1 co-occurring mutation

Yao J, Wang A, Wang X, Zhang L, Zhu Y, Ou Y, Wang Z, Yang Y

OncoTargets and Therapy 2019, 12:4261-4267

Published Date: 29 May 2019

Original Research

High LAMC1 expression in glioma is associated with poor prognosis

Liu J, Liu D, Yang Z, Yang Z

OncoTargets and Therapy 2019, 12:4253-4260

Published Date: 29 May 2019

Original Research

Androgen receptor promotes oral squamous cell carcinoma cell migration by increasing EGFR phosphorylation

Liu X, Qing S, Che K, Li L, Liao X

OncoTargets and Therapy 2019, 12:4245-4252

Published Date: 4 June 2019

Original Research

Neutrophil–lymphocyte ratio (NLR) predicted prognosis for advanced non-small-cell lung cancer (NSCLC) patients who received immune checkpoint blockade (ICB)

Ren F, Zhao T, Liu B, Pan L

OncoTargets and Therapy 2019, 12:4235-4244

Published Date: 29 May 2019

Original Research

miR-29a inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting DPP4

Wang Y, Han J, Lv Y, Zhang G

OncoTargets and Therapy 2019, 12:4225-4233

Published Date: 28 May 2019

Corrigendum

CD40L inhibits cell growth of THP-1 cells by suppressing the PI3K/Akt pathway [Corrigendum]

Feng Z, Chen Q, Ren M, Tian Z, Gong Y

OncoTargets and Therapy 2019, 12:4223-4224

Published Date: 28 May 2019

Review

NEDD9 overexpression predicts poor prognosis in solid cancers: a meta-analysis

Gu Y, Lu J, Chen C, Zheng F

OncoTargets and Therapy 2019, 12:4213-4222

Published Date: 28 May 2019

Original Research

β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway

Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, Wang R, Zou K, Zou L

OncoTargets and Therapy 2019, 12:4203-4211

Published Date: 28 May 2019

Original Research

Evaluation of MET T1010I and MET rs40239 single-nucleotide polymorphisms in triple-negative breast cancer: a case–control study

Kalapanida D, Zagouri F, Gazouli M, Tsiakou A, Zografos E, Dimitrakakis C, Marinopoulos S, Giannos A, Sergentanis TN, Kastritis E, Terpos E, Dimopoulos MA

OncoTargets and Therapy 2019, 12:4195-4202

Published Date: 28 May 2019

Original Research

CD48 is a key molecule of immunomodulation affecting prognosis in glioma

Zou C, Zhu C, Guan G, Guo Q, Liu T, Shen S, Yan Z, Xu X, Lin Z, Chen L, Wu A, Cheng W

OncoTargets and Therapy 2019, 12:4181-4193

Published Date: 28 May 2019

Original Research

microRNA-612 suppresses the malignant development of non-small-cell lung cancer by directly targeting bromodomain-containing protein 4

Kang X, Kong F, Wu S, Liu Q, Yang C, Wu X, Zhang W

OncoTargets and Therapy 2019, 12:4167-4179

Published Date: 28 May 2019

Original Research

Identification of key genes and pathways in Ewing’s sarcoma patients associated with metastasis and poor prognosis

Li G, Zhang P, Zhang W, Lei Z, He J, Meng J, Di T, Yan W

OncoTargets and Therapy 2019, 12:4153-4165

Published Date: 27 May 2019

Original Research

ITGA3 serves as a diagnostic and prognostic biomarker for pancreatic cancer

Jiao Y, Li Y, Liu S, Chen Q, Liu Y

OncoTargets and Therapy 2019, 12:4141-4152

Published Date: 27 May 2019

Review

Progression of the role of CRYAB in signaling pathways and cancers

Zhang JF, Liu J, Wu JL, Li WF, Chen ZW, Yang LS

OncoTargets and Therapy 2019, 12:4129-4139

Published Date: 30 May 2019

Original Research

The anti-apoptotic effect on cancer-associated fibroblasts of B7-H3 molecule enhancing the cell invasion and metastasis in renal cancer

Zhang S, Zhou C, Zhang D, Huang Z, Zhang G

OncoTargets and Therapy 2019, 12:4119-4127

Published Date: 24 May 2019

Original Research

Grape seed procyanidin B2 promotes the autophagy and apoptosis in colorectal cancer cells via regulating PI3K/Akt signaling pathway

Zhang R, Yu Q, Lu W, Shen J, Zhou D, Wang Y, Gao S, Wang Z

OncoTargets and Therapy 2019, 12:4109-4118

Published Date: 24 May 2019

Original Research

Long non-coding RNA H19 promotes the proliferation and invasion of lung cancer cells and regulates the expression of E-cadherin, N-cadherin, and vimentin

Liao S, Yu C, Liu H, Zhang C, Li Y, Zhong X

OncoTargets and Therapy 2019, 12:4099-4107

Published Date: 24 May 2019

Case report

Anlotinib is effective in the treatment of advanced carcinoma ex pleomorphic adenoma of the submandibular gland

Song S, Sui P, Li M, Zhang L, Sun D

OncoTargets and Therapy 2019, 12:4093-4097

Published Date: 24 May 2019

Original Research

ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma

Ye Z, Zeng Z, Shen Y, Yang Q, Chen D, Chen Z, Shen S

OncoTargets and Therapy 2019, 12:4081-4092

Published Date: 27 May 2019

Review

Progress in the identification of gene mutations involved in multiple myeloma

Hu Y, Chen W, Wang J

OncoTargets and Therapy 2019, 12:4075-4080

Published Date: 24 May 2019

Original Research

circANKS1B regulates FOXM1 expression and promotes cell migration and invasion by functioning as a sponge of the miR-149 in colorectal cancer

Li D, Yang R, Yang L, Wang D, Zhou X, Sun Y

OncoTargets and Therapy 2019, 12:4065-4073

Published Date: 23 May 2019

Original Research

TPM4 promotes cell migration by modulating F-actin formation in lung cancer

Zhao X, Jiang M, Wang Z

OncoTargets and Therapy 2019, 12:4055-4063

Published Date: 31 May 2019

Original Research

Calotropin activates YAP through downregulation of LATS1 in colorectal cancer cells

Zhou L, Cai L, Guo Y, Zhang H, Wang P, Yi G, Huang Y

OncoTargets and Therapy 2019, 12:4047-4054

Published Date: 23 May 2019

Original Research

Antitumor effects of conditioned media of human fetal dermal mesenchymal stem cells on melanoma cells

Sun B, Wang X, Pan Y, Jiao Y, Qi Y, Gong H, Jiang D

OncoTargets and Therapy 2019, 12:4033-4046

Published Date: 28 May 2019

Original Research

Circular RNA hsa_circ_009755 downregulation correlates with clinicopathology in oral squamous cell carcinoma

Wang Z, Tang J, Wang Y, Sun S, Chen Y, Shen Y, Yang HY

OncoTargets and Therapy 2019, 12:4025-4031

Published Date: 23 May 2019

Original Research

LncRNA GAS5-mediated miR-1323 promotes tumor progression by targeting TP53INP1 in hepatocellular carcinoma

Zhang F, Yang C, Xing Z, Liu P, Zhang B, Ma X, Huang L, Zhuang L

OncoTargets and Therapy 2019, 12:4013-4023

Published Date: 21 May 2019

Original Research

HEATR1 modulates cell survival in non-small cell lung cancer via activation of the p53/PUMA signaling pathway

He S, Ma X, Ye Y, Zhang M, Zhuang J, Song Y, Xia W

OncoTargets and Therapy 2019, 12:4001-4011

Published Date: 21 May 2019

Original Research

Analysis of risk factors for colon cancer progression

Yang Z, Chen Y, Wu D, Min Z, Quan Y

OncoTargets and Therapy 2019, 12:3991-4000

Published Date: 22 May 2019

Original Research

Insulin-like growth factor-1, metabolic abnormalities, and pathological complete remission rate in HER2-positive breast cancer patients receiving neoadjuvant therapy

Tong YW, Wang G, Wu JY, Huang O, He JR, Zhu L, Chen WG, Li YF, Chen XS, Shen KW

OncoTargets and Therapy 2019, 12:3977-3989

Published Date: 21 May 2019

Original Research

MiR-1284 suppresses gastric cancer progression by targeting EIF4A1

Wei W, Cao W, Zhan Z, Yan L, Xie Y, Xiao Q

OncoTargets and Therapy 2019, 12:3965-3976

Published Date: 21 May 2019

Original Research

Serum starvation induces cell death in NSCLC via miR-224

Wang G, Han J, Zhuang L, Li S, Gong Q, Chen Y

OncoTargets and Therapy 2019, 12:3955-3964

Published Date: 22 May 2019

Original Research

LncRNA DLX6-AS1 promotes the proliferation, invasion, and migration of non-small cell lung cancer cells by targeting the miR-27b-3p/GSPT1 axis

Sun W, Zhang L, Yan R, Yang Y, Meng X

OncoTargets and Therapy 2019, 12:3945-3954

Published Date: 22 May 2019

Original Research

Downregulation of NSD3 (WHSC1L1) inhibits cell proliferation and migration via ERK1/2 deactivation and decreasing CAPG expression in colorectal cancer cells

Yi L, Yi L, Liu Q, Li C

OncoTargets and Therapy 2019, 12:3933-3943

Published Date: 21 May 2019

Original Research

A temperature-sensitive phase-change hydrogel of tamoxifen achieves the long-acting antitumor activation on breast cancer cells

Meng D, Lei H, Zheng X, Han Y, Sun R, Zhao D, Liu R

OncoTargets and Therapy 2019, 12:3919-3931

Published Date: 24 May 2019

Original Research

Artificial microenvironment of in vitro glioblastoma cell cultures changes profile of miRNAs related to tumor drug resistance

Witusik-Perkowska M, Zakrzewska M, Jaskolski DJ, Liberski PP, Szemraj J

OncoTargets and Therapy 2019, 12:3905-3918

Published Date: 20 May 2019

Original Research

Curcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-β/Smad2/3 signaling pathway

Yin J, Wang L, Wang Y, Shen H, Wang X, Wu L

OncoTargets and Therapy 2019, 12:3893-3903

Published Date: 17 May 2019

Original Research

Mitochondria P-glycoprotein confers paclitaxel resistance on ovarian cancer cells

Guo W, Dong W, Li M, Shen Y

OncoTargets and Therapy 2019, 12:3881-3891

Published Date: 17 May 2019

Original Research

Circular RNA CDR1as acts as a sponge of miR-135b-5p to suppress ovarian cancer progression

Chen H, Mao M, Jiang J, Zhu D, Li P

OncoTargets and Therapy 2019, 12:3869-3879

Published Date: 17 May 2019

Original Research

Proteomic analysis of cerebrospinal fluid in pediatric acute lymphoblastic leukemia patients: a pilot study

Guo L, Ren H, Zeng H, Gong Y, Ma X

OncoTargets and Therapy 2019, 12:3859-3868

Published Date: 17 May 2019

Original Research

Impact of CXCR4 and CXCR7 knockout by CRISPR/Cas9 on the function of triple-negative breast cancer cells

Yang M, Zeng C, Li P, Qian L, Ding B, Huang L, Li G, Jiang H, Gong N, Wu W

OncoTargets and Therapy 2019, 12:3849-3858

Published Date: 17 May 2019

Original Research

Effect of XPC polymorphisms on the response to platinum-based chemotherapy: a meta-analysis

Xie C, Zhao J, Hua W, Tan P, Chen Y, Rui J, Sun X, Fan J, Wei X, Xu X, Yang X

OncoTargets and Therapy 2019, 12:3839-3848

Published Date: 16 May 2019

Original Research

MiR-449a regulates the cell migration and invasion of human non-small cell lung carcinoma by targeting ADAM10

Meng H, Huang Q, Zhang X, Huang J, Shen R, Zhang B

OncoTargets and Therapy 2019, 12:3829-3838

Published Date: 16 May 2019

Original Research

Prognostic significance and biological function of Lamina-associated polypeptide 2 in non-small-cell lung cancer

Liu C, Yu H, Shen X, Qiao J, Wu X, Chang J, Zhu X, Wang J, Shen X

OncoTargets and Therapy 2019, 12:3817-3827

Published Date: 16 May 2019

Original Research

Irradiation increases the immunogenicity of lung cancer cells and irradiation-based tumor cell vaccine elicits tumor-specific T cell responses in vivo

Luo L, Lv M, Zhuang X, Zhang Q, Qiao T

OncoTargets and Therapy 2019, 12:3805-3815

Published Date: 16 May 2019

Original Research

Prognostic value of preoperative computed tomography in HBV-related hepatocellular carcinoma patients after curative resection

Zhang W, Chen J, Liu L, Wang L, Liu J, Su D

OncoTargets and Therapy 2019, 12:3791-3804

Published Date: 16 May 2019

Original Research

LncRNA MIR210HG promotes proliferation and invasion of non-small cell lung cancer by upregulating methylation of CACNA2D2 promoter via binding to DNMT1

Kang X, Kong F, Huang K, Li L, Li Z, Wang X, Zhang W, Wu X

OncoTargets and Therapy 2019, 12:3779-3790

Published Date: 16 May 2019

Original Research

microRNA-605 inhibits the oncogenicity of non-small-cell lung cancer by directly targeting Forkhead Box P1

Zhou W, Li R

OncoTargets and Therapy 2019, 12:3765-3777

Published Date: 17 May 2019

Original Research

ITGBL1 promotes EMT, invasion and migration by activating NF-κB signaling pathway in prostate cancer

Li W, Li S, Yang J, Cui C, Yu M, Zhang Y

OncoTargets and Therapy 2019, 12:3753-3763

Published Date: 16 May 2019

Original Research

Homeobox B7 accelerates the cancer progression of gastric carcinoma cells by promoting epithelial–mesenchymal transition (EMT) and activating Src–FAK pathway

Wu J, Long Z, Cai H, Yu S, Liu X

OncoTargets and Therapy 2019, 12:3743-3751

Published Date: 16 May 2019

Original Research

Downregulation of GBAS regulates oral squamous cell carcinoma proliferation and apoptosis via the p53 signaling pathway

Wang X, Bai Y, Han Y, Meng J, Liu H

OncoTargets and Therapy 2019, 12:3729-3742

Published Date: 17 May 2019

Original Research

Efficacy and tolerability of stereotactic body radiotherapy for lung metastases in three patients with pediatric malignancies

Deck J, Eastwick G, Sima J, Raymond A, Bogart J, Aridgides P

OncoTargets and Therapy 2019, 12:3723-3727

Published Date: 15 May 2019

Original Research

Anti-tumor effect of aloe-emodin on cervical cancer cells was associated with human papillomavirus E6/E7 and glucose metabolism

Gao R, Wu X, Huang Z, Wang B, Li F, Xu H, Ran L

OncoTargets and Therapy 2019, 12:3713-3721

Published Date: 14 May 2019

Original Research

Identification and validation of an individualized autophagy-clinical prognostic index in bladder cancer patients

Wang SS, Chen G, Li SH, Pang JS, Cai KT, Yan HB, Huang ZG, He RQ

OncoTargets and Therapy 2019, 12:3695-3712

Published Date: 14 May 2019

Original Research

Identification of key genes and pathways in seminoma by bioinformatics analysis

Chen YH, Lin TT, Wu YP, Li XD, Chen SH, Xue XY, Wei Y, Zheng QS, Huang JB, Xu N

OncoTargets and Therapy 2019, 12:3683-3693

Published Date: 14 May 2019

Review

Prognostic and clinicopathological value of PD-L1 in colorectal cancer: a systematic review and meta-analysis

Yang L, Xue R, Pan C

OncoTargets and Therapy 2019, 12:3671-3682

Published Date: 14 May 2019

Original Research

Insulin-like growth factor II mRNA-binding protein 3 promotes cell proliferation, migration and invasion in human glioblastoma

Wu C, Ma H, Qi G, Chen F, Chu J

OncoTargets and Therapy 2019, 12:3661-3670

Published Date: 15 May 2019

Review

The role of circadian clock genes in tumors

Li HX

OncoTargets and Therapy 2019, 12:3645-3660

Published Date: 13 May 2019

Case report

Long-term progression-free survival of apatinib monotherapy for relapsed ovarian cancer: a case report and literature review

Zhang D, Huang J, Sun Y, Guo Q

OncoTargets and Therapy 2019, 12:3635-3644

Published Date: 15 May 2019

Original Research

PAQR4 promotes cell proliferation and metastasis through the CDK4-pRB-E2F1 pathway in non-small-cell lung cancer

Wu B, Liu R

OncoTargets and Therapy 2019, 12:3625-3633

Published Date: 13 May 2019

Review

Novel cancer therapy targeting microbiome

Nagano T, Otoshi T, Hazama D, Kiriu T, Umezawa K, Katsurada N, Nishimura Y

OncoTargets and Therapy 2019, 12:3619-3624

Published Date: 13 May 2019

Review

Clinicopathological and prognostic significance of Nanog expression in non-small cell lung cancer: a meta-analysis

Huang G, Zhang J, Wang X, Chen Y, Liu D, Guo S

OncoTargets and Therapy 2019, 12:3609-3617

Published Date: 13 May 2019

Original Research

miR-106b promotes proliferation and invasion by targeting Capicua through MAPK signaling in renal carcinoma cancer

Miao LJ, Yan S, Zhuang QF, Mao QY, Xue D, He XZ, Chen JP

OncoTargets and Therapy 2019, 12:3595-3607

Published Date: 13 May 2019

Original Research

The reversal of MRP1 expression induced by low-frequency and low-intensity ultrasound and curcumin mediated by VEGF in brain glioma

Yao L, Zhang Z

OncoTargets and Therapy 2019, 12:3581-3593

Published Date: 13 May 2019

Original Research

Polymorphism of miRNA and esophageal cancer risk: an updated systemic review and meta-analysis

Guo X, Zhao L, Shen Y, Shao Y, Wei W, Liu F

OncoTargets and Therapy 2019, 12:3565-3580

Published Date: 23 May 2019

Original Research

Identification of novel biomarkers and candidate small molecule drugs in non-small-cell lung cancer by integrated microarray analysis

Wu Q, Zhang B, Sun Y, Xu R, Hu X, Ren S, Ma Q, Chen C, Shu J, Qi F, He T, Wang W, Wang Z

OncoTargets and Therapy 2019, 12:3545-3563

Published Date: 13 May 2019

Original Research

miR-129-5p inhibits prostate cancer proliferation via targeting ETV1

Gao G, Xiu D, Yang B, Sun D, Wei X, Ding Y, Ma Y, Wang Z

OncoTargets and Therapy 2019, 12:3531-3544

Published Date: 9 May 2019

Original Research

c-Src is required for hypoxia-induced metastasis-associated functions in prostate cancer cells

Dai Y, Siemann D

OncoTargets and Therapy 2019, 12:3519-3529

Published Date: 8 May 2019

Original Research

Long non-coding RNA homeobox A11 antisense RNA (HOXA11-AS) promotes retinoblastoma progression via sponging miR-506-3p

Han N, Zuo L, Chen H, Zhang C, He P, Yan H

OncoTargets and Therapy 2019, 12:3509-3517

Published Date: 7 May 2019

Original Research

INPP4B inhibits cell proliferation, invasion and chemoresistance in human hepatocellular carcinoma

Tang W, Yang L, Yang T, Liu M, Zhou Y, Lin J, Wang K, Ding C

OncoTargets and Therapy 2019, 12:3491-3507

Published Date: 7 May 2019

Original Research

miR-125a-5p inhibits colorectal cancer cell epithelial–mesenchymal transition, invasion and migration by targeting TAZ

Tang L, Zhou L, Wu S, Shi X, Jiang G, Niu S, Ding D

OncoTargets and Therapy 2019, 12:3481-3489

Published Date: 7 May 2019

Original Research

Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis

Xu W, Hu GQ, Da Costa C, Tang JH, Li QR, Du L, Pan YW, Lv SQ

OncoTargets and Therapy 2019, 12:3467-3480

Published Date: 7 May 2019

Original Research

The clinical efficacy of ultrasound-guided percutaneous microwave ablation for rib metastases with severe intractable pain: a preliminary clinical study

Cheng Z, Li X, An C, Yu X, Yu J, Han Z, Liu F, Liang P

OncoTargets and Therapy 2019, 12:3459-3465

Published Date: 7 May 2019

Original Research

Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer

Zhu H, Chen H, Wang J, Zhou L, Liu S

OncoTargets and Therapy 2019, 12:3441-3457

Published Date: 7 May 2019

Original Research

The functions of microRNA-124 on bladder cancer

Cao Z, Xu L, Zhao S, Zhu X

OncoTargets and Therapy 2019, 12:3429-3439

Published Date: 7 May 2019

Original Research

KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA

Cheng X, Li M, Rao X, Zhang W, Li X, Wang L, Huang G

OncoTargets and Therapy 2019, 12:3421-3428

Published Date: 7 May 2019

Review

Research progress of cystatin SN in cancer

Liu Y, Yao J

OncoTargets and Therapy 2019, 12:3411-3419

Published Date: 6 May 2019

Original Research

Assessment of tumor mutation burden calculation from gene panel sequencing data

Xu Z, Dai J, Wang D, Lu H, Dai H, Ye H, Gu J, Chen S, Huang B

OncoTargets and Therapy 2019, 12:3401-3409

Published Date: 6 May 2019

Review

Pancreatic cancer in young adults: changes, challenges, and solutions

Primavesi F, Stättner S, Schlick K, Kiesslich T, Mayr C, Klieser E, Urbas R, Neureiter D

OncoTargets and Therapy 2019, 12:3387-3400

Published Date: 6 May 2019

Original Research

Long non-coding RNA CASC2 serves as a ceRNA of microRNA-21 to promote PDCD4 expression in oral squamous cell carcinoma

Pan L, Chen H, Bai Y, Wang Q, Chen L

OncoTargets and Therapy 2019, 12:3377-3385

Published Date: 6 May 2019

Case report

Multiple myeloma with dural mater involvement

Liu S, Li X, Li Y, Li D, Wang Y, Tian C

OncoTargets and Therapy 2019, 12:3373-3375

Published Date: 3 May 2019

Original Research

CircHIPK3 overexpression accelerates the proliferation and invasion of prostate cancer cells through regulating miRNA-338-3p

Cai C, Zhi Y, Wang K, Zhang P, Ji Z, Xie C, Sun F

OncoTargets and Therapy 2019, 12:3363-3372

Published Date: 2 May 2019

Corrigendum

Overexpression of APC11 predicts worse survival in lung adenocarcinoma [Corrigendum]

Zhou J, Zhang S, Fu G, He Z, Xu Y, Ye W, Chen Z

OncoTargets and Therapy 2019, 12:3361-3362

Published Date: 2 May 2019

Original Research

LncRNA SNHG6 promotes the migration, invasion, and epithelial-mesenchymal transition of colorectal cancer cells by miR-26a/EZH2 axis

Zhang M, Duan W, Sun W

OncoTargets and Therapy 2019, 12:3349-3360

Published Date: 2 May 2019

Original Research

Fatty acid synthase enhances colorectal cancer cell proliferation and metastasis via regulating AMPK/mTOR pathway

Lu T, Sun L, Wang Z, Zhang Y, He Z, Xu C

OncoTargets and Therapy 2019, 12:3339-3347

Published Date: 2 May 2019

Original Research

Nicotine promotes cervical metastasis of oral cancer by regulating peroxiredoxin 1 and epithelial–mesenchymal transition in mice

Wang M, Niu W, Qi M, Chen H, Zhang M, Wang C, Ge L, Yang J, Miao C, Shi N, Chen T, Tang X

OncoTargets and Therapy 2019, 12:3327-3338

Published Date: 1 May 2019

Case report

Poor prognosis of pulmonary sarcomatoid carcinoma with KRAS mutation and ALK fusion

Chen F, Gu Q, Hu C, Cai X, Lei S

OncoTargets and Therapy 2019, 12:3321-3325

Published Date: 1 May 2019

Original Research

Altered circulating levels of adipokine omentin-1 in patients with prostate cancer

Zhou L, He W, Wang W, Zhou D

OncoTargets and Therapy 2019, 12:3313-3319

Published Date: 1 May 2019

Original Research

High feasibility of cytological specimens for detection of ROS1 fusion by reverse transcriptase PCR in Chinese patients with advanced non-small-cell lung cancer

Zhang L, Wang Y, Zhao C, Shi J, Zhao S, Liu X, Jia Y, Zhu T, Jiang T, Li X, Zhou C

OncoTargets and Therapy 2019, 12:3305-3311

Published Date: 1 May 2019

Original Research

Increased MCL-1 expression predicts poor prognosis and disease recurrence in acute myeloid leukemia

Li XX, Zhou JD, Wen XM, Zhang TJ, Wu DH, Deng ZQ, Zhang ZH, Lian XY, He PF, Yao XY, Lin J, Qian J

OncoTargets and Therapy 2019, 12:3295-3304

Published Date: 1 May 2019

Original Research

MEX3C regulates lipid metabolism to promote bladder tumorigenesis through JNK pathway

Chao H, Deng L, Xu F, Yu Z, Xu X, Huang J, Zeng T

OncoTargets and Therapy 2019, 12:3285-3294

Published Date: 1 May 2019

Original Research

Crossover safety study of aprepitant: 2-min injection vs 30-min infusion in cancer patients receiving emetogenic chemotherapy

Navari RM, Mosier MC

OncoTargets and Therapy 2019, 12:3277-3284

Published Date: 30 April 2019

Original Research

Ribonucleotide reductase subunit M2 as a novel target for clear-cell renal cell carcinoma

Zou Y, Zhou J, Xu B, Li W, Wang Z

OncoTargets and Therapy 2019, 12:3267-3275

Published Date: 30 April 2019

Original Research

MicroRNA-143-3p suppresses tumorigenesis by targeting catenin-δ1 in colorectal cancer

Ding X, Du J, Mao K, Wang X, Ding Y, Wang F

OncoTargets and Therapy 2019, 12:3255-3265

Published Date: 1 May 2019

Review

Advancements of Annexin A1 in inflammation and tumorigenesis

Shao G, Zhou H, Zhang Q, Jin Y, Fu C

OncoTargets and Therapy 2019, 12:3245-3254

Published Date: 30 April 2019

Review

NUT midline carcinoma of the head and neck: current perspectives

Napolitano M, Venturelli M, Molinaro E, Toss A

OncoTargets and Therapy 2019, 12:3235-3244

Published Date: 30 April 2019

Original Research

Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer

Liang J, Han B, Zhang Y, Yue Q

OncoTargets and Therapy 2019, 12:3223-3233

Published Date: 29 April 2019

Original Research

Fibronectin 1 promotes melanoma proliferation and metastasis by inhibiting apoptosis and regulating EMT

Li B, Shen W, Peng H, Li Y, Chen F, Zheng L, Xu J, Jia L

OncoTargets and Therapy 2019, 12:3207-3221

Published Date: 1 May 2019

Original Research

Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling

Qian S, Tan X, Liu X, Liu P, Wu Y

OncoTargets and Therapy 2019, 12:3197-3205

Published Date: 29 April 2019

Original Research

MiR-155-5p accelerates the metastasis of cervical cancer cell via targeting TP53INP1

Li N, Cui T, Guo WL, Wang DW, Mao L

OncoTargets and Therapy 2019, 12:3181-3196

Published Date: 29 April 2019

Review

Antitumor activity of larotrectinib in tumors harboring NTRK gene fusions: a short review on the current evidence

Ricciuti B, Genova C, Crinò L, Libra M, Leonardi GC

OncoTargets and Therapy 2019, 12:3171-3179

Published Date: 30 April 2019

Original Research

GADD45α-targeted suicide gene therapy driven by synthetic CArG promoter E9NS sensitizes NSCLC cells to cisplatin, resveratrol, and radiation regardless of p53 status

Shi Q, Sutariya V, Varghese Gupta S, Bhatia D

OncoTargets and Therapy 2019, 12:3161-3170

Published Date: 26 April 2019

Original Research

Cinobufotalin as an effective adjuvant therapy for advanced gastric cancer: a meta-analysis of randomized controlled trials

Sun H, Wang W, Bai M, Liu D

OncoTargets and Therapy 2019, 12:3139-3160

Published Date: 26 April 2019

Original Research

Expression and significance of LncRNA MNX1-AS1 in non-small cell lung cancer

Liu G, Guo X, Zhang Y, Liu Y, Li D, Tang G, Cui S

OncoTargets and Therapy 2019, 12:3129-3138

Published Date: 26 April 2019

Review

Expression level and clinical significance of SNHG1 in human cancers: a meta-analysis

Yu Y, Yang J, Yang S, Li Q, Zhang M, Wang L, Ji G, Miao L

OncoTargets and Therapy 2019, 12:3119-3127

Published Date: 24 April 2019

Original Research

INPP4B promotes colorectal cancer cell proliferation by activating mTORC1 signaling and cap-dependent translation

Ruan X, Liu X, Yang Z, Zhang S, Li Q, Lin C

OncoTargets and Therapy 2019, 12:3109-3117

Published Date: 23 April 2019

Original Research

MiR-145 inhibits EGF-induced epithelial-to-mesenchymal transition via targeting Smad2 in human glioblastoma

Chen W, Huang B, Wang E, Wang X

OncoTargets and Therapy 2019, 12:3099-3107

Published Date: 23 April 2019

Original Research

Retinoic acid receptor α facilitates human colorectal cancer progression via Akt and MMP2 signaling

Huang GL, Chen QX, Ma JJ, Sui SY, Wang YN, Shen DY

OncoTargets and Therapy 2019, 12:3087-3098

Published Date: 23 April 2019

Original Research

Modified FOLFIRINOX for unresectable locally advanced/metastatic pancreatic cancer. A real-world comparison of an attenuated with a full dose in a single center experience

Cavanna L, Stroppa EM, Citterio C, Mordenti P, Di Nunzio C, Peveri S, Orlandi E, Vecchia S

OncoTargets and Therapy 2019, 12:3077-3085

Published Date: 23 April 2019

Original Research

hMOF reduction enhances radiosensitivity through the homologous recombination pathway in non-small-cell lung cancer

Li N, Tian GW, Tang LR, Li G

OncoTargets and Therapy 2019, 12:3065-3075

Published Date: 23 April 2019

Original Research

M2 macrophages confer resistance to 5-fluorouracil in colorectal cancer through the activation of CCL22/PI3K/AKT signaling

Wei C, Yang C, Wang S, Shi D, Zhang C, Lin X, Xiong B

OncoTargets and Therapy 2019, 12:3051-3063

Published Date: 18 April 2019

Original Research

Pim-1 inhibitor SMI-4a suppresses tumor growth in non-small cell lung cancer via PI3K/AKT/mTOR pathway

Jiang W, Chen Y, Song X, Shao Y, Ning Z, Gu W

OncoTargets and Therapy 2019, 12:3043-3050

Published Date: 23 April 2019

Original Research

ZNF277 regulates ovarian cancer cell proliferation and invasion through inhibition of PTEN

Liu Z, Xu Z, Tian Y, Yan H, Lou Y

OncoTargets and Therapy 2019, 12:3031-3042

Published Date: 18 April 2019

Original Research

NRF3 suppresses breast cancer cell metastasis and cell proliferation and is a favorable predictor of survival in breast cancer

Sun J, Zheng Z, Chen Q, Pan Y, Lu H, Zhang H, Yu Y, Dai Y

OncoTargets and Therapy 2019, 12:3019-3030

Published Date: 18 April 2019

Original Research

CD40L inhibits cell growth of THP-1 cells by suppressing the PI3K/Akt pathway

Feng Z, Chen Q, Ren M, Tian Z, Gong Y

OncoTargets and Therapy 2019, 12:3011-3017

Published Date: 18 April 2019

Original Research

MiR-216b suppresses cell proliferation, migration, invasion, and epithelial–mesenchymal transition by regulating FOXM1 expression in human non-small cell lung cancer

Wang L, Wang Y, Du X, Yao Y, Wang L, Jia Y

OncoTargets and Therapy 2019, 12:2999-3009

Published Date: 18 April 2019

Expert Opinion

Treating advanced breast cancer with metronomic chemotherapy: what is known, what is new and what is the future?

Cazzaniga ME, Biganzoli L, Cortesi L, De Placido S, Donadio M, Fabi A, Ferro A, Generali D, Lorusso V, Milani A, Montagna E, Munzone E, Orlando L, Pizzuti L, Simoncini E, Zamagni C, Pappagallo GL

OncoTargets and Therapy 2019, 12:2989-2997

Published Date: 23 April 2019

Original Research

Profile of lenvatinib in the treatment of hepatocellular carcinoma: design, development, potential place in therapy and network meta-analysis of hepatitis B and hepatitis C in all Phase III trials

Casadei Gardini A, Puzzoni M, Montagnani F, Marisi G, Tamburini E, Cucchetti A, Solaini L, Foschi FG, Conti F, Ercolani G, Cascinu S, Scartozzi M

OncoTargets and Therapy 2019, 12:2981-2988

Published Date: 24 April 2019

Case report

Large-cell neuroendocrine carcinoma of nasal cavity and paranasal sinuses after successful curative therapy: a case report and literature review

Zhao Q, Wei J, Zhang C, Meng L, Wang B, Gao L, Jiang X

OncoTargets and Therapy 2019, 12:2975-2980

Published Date: 17 April 2019

Original Research

LncRNA MIR100HG promotes cancer cell proliferation, migration and invasion in laryngeal squamous cell carcinoma through the downregulation of miR-204-5p

Huang Y, Zhang C, Zhou Y

OncoTargets and Therapy 2019, 12:2967-2973

Published Date: 17 April 2019

Original Research

Expression of FOXP1 and FOXO3a in extrahepatic cholangiocarcinoma and the implications in clinicopathological significance and prognosis

He J, Yang Z, Wu Z, Wang L, Xu S, Zou Q, Yuan Y, Li D

OncoTargets and Therapy 2019, 12:2955-2965

Published Date: 17 April 2019

Case report

Successful treatment with cryoablation in a patient with bone metastasis in the mid-shaft femur: a case report

Kita K, Nakamura T, Yamanaka T, Yoshida K, Hagi T, Asanuma K, Nakatsuka A, Sudo A

OncoTargets and Therapy 2019, 12:2949-2953

Published Date: 17 April 2019

Case report

Refinement of diagnosis and supporting evidence for the use of immunotherapy through sequential biopsies in a case of EML4-ALK positive lung cancer

Song P, Zhang J, Zhang L

OncoTargets and Therapy 2019, 12:2943-2948

Published Date: 17 April 2019

Case report

CD5-negative chronic lymphocytic leukemia/small lymphocytic lymphoma in a patient with gastrointestinal mantle cell lymphoma: an unusual case report

Chen D, Zhan Y, Peng J, Yao F

OncoTargets and Therapy 2019, 12:2937-2941

Published Date: 17 April 2019

Case report

A significant response to a combination of trastuzumab and vinorelbine in HER2-negative metastatic breast cancer with HER2 V777L mutation

Lei L, Ye W, Zheng L, Huang P, Shi L, Huang J, Zheng Y, Chen Z, Wang X, Wang X

OncoTargets and Therapy 2019, 12:2931-2936

Published Date: 17 April 2019

Original Research

Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells

Hao Y, Bai X, Liu X, Kang S, Zhang X, Liu C, Li Z

OncoTargets and Therapy 2019, 12:2921-2930

Published Date: 17 April 2019

Original Research

Neuropilin-1 is associated with the prognosis of cervical cancer in Henan Chinese population

Yang L, Liu L, Zhu YH, Wang BB, Chen YN, Zhang F, Zhang XA, Ren CC

OncoTargets and Therapy 2019, 12:2911-2920

Published Date: 17 April 2019

Review

MDM2 antagonists as a novel treatment option for acute myeloid leukemia: perspectives on the therapeutic potential of idasanutlin (RG7388)

Khurana A, Shafer DA

OncoTargets and Therapy 2019, 12:2903-2910

Published Date: 16 April 2019

Original Research

Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling

Liu L, Li Y, Pan B, Zhang T, Wei D, Zhu Y, Guo Y

OncoTargets and Therapy 2019, 12:2891-2902

Published Date: 17 April 2019

Original Research

Leptin rs7799039 (G2548A) polymorphism is associated with cancer risk: a meta-analysis involving 25,799 subjects

Tang W, Kang M, Liu C, Qiu H

OncoTargets and Therapy 2019, 12:2879-2890

Published Date: 16 April 2019

Original Research

Notch pathway is involved in the suppression of colorectal cancer by embryonic stem cell microenvironment

Lan G, Lin Z, Zhang J, Liu L, Zhang J, Zheng L, Luo Q

OncoTargets and Therapy 2019, 12:2869-2878

Published Date: 16 April 2019

Original Research

SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species

Yu W, Yang Z, Huang R, Min Z, Ye M

OncoTargets and Therapy 2019, 12:2861-2868

Published Date: 15 April 2019

Original Research

Prognostic significance of EIF4G1 in patients with pancreatic ductal adenocarcinoma

Goh TS, Ha M, Lee JS, Jeong DC, Jung ES, Han ME, Kim YH, Oh SO

OncoTargets and Therapy 2019, 12:2853-2859

Published Date: 15 April 2019

Original Research

Decreased expression of aquaporin 1 correlates with clinicopathological features of patients with cervical cancer

Wei M, Yu H, Zhang Y, Zeng J, Cai C, Shi R

OncoTargets and Therapy 2019, 12:2843-2851

Published Date: 23 April 2019

Original Research

FAM111B, a direct target of p53, promotes the malignant process of lung adenocarcinoma

Sun H, Liu K, Huang J, Sun Q, Shao C, Luo J, Xu L, Shen Y, Ren B

OncoTargets and Therapy 2019, 12:2829-2842

Published Date: 17 April 2019

Case report

Sunitinib-and-Chinese herbal medicine-based systematic treatment clinically cured a patient with multiple metastatic primary clear cell carcinoma of the liver: a case report

Sun L, Chen H, Xiao Z, Guo W, Lin L

OncoTargets and Therapy 2019, 12:2823-2828

Published Date: 12 April 2019

Original Research

MicroRNA-940 restricts the expression of metastasis-associated gene MACC1 and enhances the antitumor effect of Anlotinib on colorectal cancer

Wang Y, Zhao M, Zhao H, Cheng S, Bai R, Song M

OncoTargets and Therapy 2019, 12:2809-2822

Published Date: 12 April 2019

Original Research

Aberrant expression of PAFAH1B3 associates with poor prognosis and affects proliferation and aggressiveness in hypopharyngeal squamous cell carcinoma

Xu J, Zang Y, Cao S, Lei D, Pan X

OncoTargets and Therapy 2019, 12:2799-2808

Published Date: 11 April 2019

Original Research

Stanniocalcin 1 in tumor microenvironment promotes metastasis of ovarian cancer

Yang Y, Yin S, Li S, Chen Y, Yang L

OncoTargets and Therapy 2019, 12:2789-2798

Published Date: 11 April 2019

Original Research

Pyrotinib treatment on HER2-positive gastric cancer cells promotes the released exosomes to enhance endothelial cell progression, which can be counteracted by apatinib

Gao Z, Song C, Li G, Lin H, Lian X, Zhang N, Cao B

OncoTargets and Therapy 2019, 12:2777-2787

Published Date: 11 April 2019

Original Research

The proliferation of cervical cancer is promoted by miRNA-125b through the regulation of the HMGA1

Sun B, Zhang Y, Zhou L, Yin L, Li F, Li C, Xia J

OncoTargets and Therapy 2019, 12:2767-2776

Published Date: 11 April 2019

Original Research

Rituximab-based combination therapy in patients with Waldenström macroglobulinemia: a systematic review and meta-analysis

Zheng YH, Xu L, Cao C, Feng J, Tang HL, Shu M, Gao GX, Chen X

OncoTargets and Therapy 2019, 12:2751-2766

Published Date: 11 April 2019

Corrigendum

Efficacy and safety of apatinib treatment for gastric cancer, hepatocellular carcinoma and non-small cell lung cancer: a meta-analysis [Corrigendum]

Xue J, Astère M, Zhong M, Lin H, Shen J, Zhu Y

OncoTargets and Therapy 2019, 12:2749-2750

Published Date: 11 April 2019

Original Research

Whole transcriptome sequencing identifies crucial genes associated with colon cancer and elucidation of their possible mechanisms of action

Yang Y, Zhao Y, Zhang W, Bai Y

OncoTargets and Therapy 2019, 12:2737-2747

Published Date: 10 April 2019

Case report

Successful treatment of brain radiation necrosis resulting from triple-negative breast cancer with Endostar and short-term hyperbaric oxygen therapy: a case report

Xing S, Fan Z, Shi L, Yang Z, Bai Y

OncoTargets and Therapy 2019, 12:2729-2735

Published Date: 10 April 2019

Original Research

miR-19 promotes the proliferation of clear cell renal cell carcinoma by targeting the FRK–PTEN axis

Jing ZF, Bi JB, Li ZL, Liu XK, Li J, Zhu YY, Zhang XT, Zhang Z, Li ZH, Kong CZ

OncoTargets and Therapy 2019, 12:2713-2727

Published Date: 10 April 2019

Original Research

IL-37 promotes cell apoptosis in cervical cancer involving Bim upregulation

Ouyang P, An W, Chen R, Zhang H, Chen D, Jiang E, Zhu W, Li P, Guo H, Chen Z, Wang S

OncoTargets and Therapy 2019, 12:2703-2712

Published Date: 10 April 2019

Original Research

Clinicopathological impacts of c-Met overexpression in bladder cancer: evidence from 1,336 cases

Xu X, Zhang G, He L, Zhu Y

OncoTargets and Therapy 2019, 12:2695-2702

Published Date: 10 April 2019

Original Research

Overexpression of PRR11 promotes tumorigenic capability and is associated with progression in esophageal squamous cell carcinoma

Zhou L, Deng Z, Li H, Jiang N, Wei Z, Hong M, Wang J, Zhang M, Shi Y, Lu Z, Huang X

OncoTargets and Therapy 2019, 12:2677-2693

Published Date: 9 April 2019

Original Research

Cell-free miR-17-5p as a diagnostic biomarker for gastric cancer inhibits dendritic cell maturation

Cui ZJ, Xie XL, Qi W, Yang YC, Bai Y, Han J, Ding Q, Jiang HQ

OncoTargets and Therapy 2019, 12:2661-2675

Published Date: 9 April 2019

Original Research

lncRNA KCNQ1OT1 enhances the chemoresistance of oxaliplatin in colon cancer by targeting the miR-34a/ATG4B pathway

Li Y, Li C, Li D, Yang L, Jin J, Zhang B

OncoTargets and Therapy 2019, 12:2649-2660

Published Date: 9 April 2019

Original Research

High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center

Li Y, Fang D, Bao Z, He A, Guan B, He S, Zhan Y, Gong Y, Li X, Zhou L

OncoTargets and Therapy 2019, 12:2635-2648

Published Date: 11 April 2019

Original Research

Diagnostic value of circular RNAs as effective biomarkers for cancer: a systematic review and meta-analysis

Tan H, Gan L, Fan X, Liu L, Liu S

OncoTargets and Therapy 2019, 12:2623-2633

Published Date: 10 April 2019

Original Research

miRNA-99b-5p targets FZD8 to inhibit non-small cell lung cancer proliferation, migration and invasion

Liu R, Chen Y, Shou T, Hu J, Qing C

OncoTargets and Therapy 2019, 12:2615-2621

Published Date: 8 April 2019

Original Research

Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression

Liu T, Sun X, Cao Z

OncoTargets and Therapy 2019, 12:2605-2614

Published Date: 9 April 2019

Original Research

Long noncoding RNA LINC00515 promotes cell proliferation and inhibits apoptosis by sponging miR-16 and activating PRMT5 expression in human glioma

Wu Z, Lin Y

OncoTargets and Therapy 2019, 12:2595-2604

Published Date: 8 April 2019

Original Research

SMYD2-OE promotes oxaliplatin resistance in colon cancer through MDR1/P-glycoprotein via MEK/ERK/AP1 pathway

Ren H, Wang Z, Chen Y, Liu Y, Zhang S, Zhang T, Li Y

OncoTargets and Therapy 2019, 12:2585-2594

Published Date: 8 April 2019

Original Research

Clinical efficacy and survival analysis of apatinib combined with docetaxel in advanced esophageal cancer

Li J, Jia YX, Gao YP, Chang ZW, Han HQ, Yan J, Qin YR

OncoTargets and Therapy 2019, 12:2577-2583

Published Date: 8 April 2019

Original Research

LncRNA PVT1 promotes proliferation, invasion and epithelial–mesenchymal transition of renal cell carcinoma cells through downregulation of miR-16-5p

Ren Y, Huang W, Weng G, Cui P, Liang H, Li Y

OncoTargets and Therapy 2019, 12:2563-2575

Published Date: 5 April 2019

Original Research

Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53

Weng C, Chen Y, Wu Y, Liu X, Mao H, Fang X, Li B, Wang L, Guan M, Liu G, Lu L, Yuan Y

OncoTargets and Therapy 2019, 12:2553-2561

Published Date: 8 April 2019

Original Research

The diagnostic value of circulating tumor cells and ctDNA for gene mutations in lung cancer

Lyu M, Zhou J, Ning K, Ying B

OncoTargets and Therapy 2019, 12:2539-2552

Published Date: 5 April 2019

Case report

Long-term response of metastatic renal clear cell carcinoma following a subcutaneous injection of mixed bacterial vaccine: a case report

Chen J, Lv Y, Mu F, Xu K

OncoTargets and Therapy 2019, 12:2531-2538

Published Date: 5 April 2019

Original Research

SIRT1 inhibits hepatocellular carcinoma metastasis by promoting M1 macrophage polarization via NF-κB pathway

Zhou B, Yang Y, Li C

OncoTargets and Therapy 2019, 12:2519-2529

Published Date: 4 April 2019

Original Research

Clinical outcome of osteosarcoma and its correlation with programmed death-ligand 1 and T cell activation markers

Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, Okano S, Ideta H, Kamanaka T, Sobajima A, Takizawa T, Kito M, Aoki K, Uemura T, Haniu H, Kato H, Saito N

OncoTargets and Therapy 2019, 12:2513-2518

Published Date: 3 April 2019

Review

Durvalumab for the management of urothelial carcinoma: a short review on the emerging data and therapeutic potential

Baldini C, Champiat S, Vuagnat P, Massard C

OncoTargets and Therapy 2019, 12:2505-2512

Published Date: 3 April 2019

Original Research

Association of polymorphisms in MALAT1 with the risk of esophageal squamous cell carcinoma in a Chinese population

Qu Y, Shao N, Yang W, Wang J, Cheng Y

OncoTargets and Therapy 2019, 12:2495-2503

Published Date: 3 April 2019

Original Research

Combination treatment with cetuximab in advanced nasopharyngeal carcinoma patients: a meta-analysis

Shen J, Sun C, Zhou M, Zhang Z

OncoTargets and Therapy 2019, 12:2477-2494

Published Date: 3 April 2019

Original Research

SOX5 promotes cell invasion and metastasis via activation of Twist-mediated epithelial–mesenchymal transition in gastric cancer

You J, Zhao Q, Fan X, Wang J

OncoTargets and Therapy 2019, 12:2465-2476

Published Date: 3 April 2019

Original Research

LKB1 suppresses glioma cell invasion via NF-κB/Snail signaling repression

Yuan Y, Li SL, Cao YL, Li JJ, Wang QP

OncoTargets and Therapy 2019, 12:2451-2463

Published Date: 2 April 2019

Original Research

Differentiation antagonizing non-protein coding RNA modulates the proliferation, migration, and angiogenesis of glioma cells by targeting the miR-216a/LGR5 axis and the PI3K/AKT signaling pathway

Wang W, Li Y, Ma Q, Yan H, Su W

OncoTargets and Therapy 2019, 12:2439-2449

Published Date: 4 April 2019

Case report

Hepatopulmonary syndrome after radiofrequency ablation of recurrent intrahepatic cholangiocarcinoma: a case report

Wang Y, Ma K, Zhong A, Xiong Q, Chen J

OncoTargets and Therapy 2019, 12:2431-2438

Published Date: 2 April 2019

Case report

Clinical treatment of advanced synchronous triple primary malignancies: comprehensive treatment based on targeted therapy

Zhang Y, Ge Y, Wu X, Liu S

OncoTargets and Therapy 2019, 12:2421-2430

Published Date: 2 April 2019

Original Research

Histone deacetylase 6 is overexpressed and promotes tumor growth of colon cancer through regulation of the MAPK/ERK signal pathway

Zhang SL, Zhu HY, Zhou BY, Chu Y, Huo JR, Tan YY, Liu DL

OncoTargets and Therapy 2019, 12:2409-2419

Published Date: 2 April 2019

Original Research

SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism

Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G

OncoTargets and Therapy 2019, 12:2397-2408

Published Date: 28 March 2019

Original Research

Luteolin suppresses tumor proliferation through inducing apoptosis and autophagy via MAPK activation in glioma

You Y, Wang R, Shao N, Zhi F, Yang Y

OncoTargets and Therapy 2019, 12:2383-2396

Published Date: 28 March 2019

Original Research

Overexpression of miR-664 is associated with poor overall survival and accelerates cell proliferation, migration and invasion in hepatocellular carcinoma

Wang X, Zhou Z, Zhang T, Wang M, Xu R, Qin S, Zhang S

OncoTargets and Therapy 2019, 12:2373-2381

Published Date: 28 March 2019

Case report

Postchemotherapy sarcoma as a somatic-type malignancy derived from the gonadal yolk sac tumor in a patient with 46, XY pure gonadal dysgenesis

Zong X, Yang JX, Zhang Y, Cao DY, Shen K, You Y, Guo LN

OncoTargets and Therapy 2019, 12:2365-2372

Published Date: 28 March 2019

Original Research

Tumor necrosis factor α knockout impaired tumorigenesis in chronic myeloid leukemia cells partly by metabolism modification and miRNA regulation

Shen N, Liu S, Cui J, Li Q, You Y, Zhong Z, Cheng F, Guo AY, Zou P, Yuan G, Zhu X

OncoTargets and Therapy 2019, 12:2355-2364

Published Date: 29 March 2019

Original Research

1,25-Dihydroxyvitamin D3 affects gastric cancer progression by repressing BMP3 promoter methylation

Zhao Y, Cai LL, Wang HL, Shi XJ, Ye HM, Song P, Huang BQ, Tzeng CM

OncoTargets and Therapy 2019, 12:2343-2353

Published Date: 28 March 2019

Original Research

Comparison of CHOP vs CHOPE for treatment of peripheral T-cell lymphoma: a meta-analysis

Deng S, Lin S, Shen J, Zeng Y

OncoTargets and Therapy 2019, 12:2335-2342

Published Date: 28 March 2019

Original Research

MicroRNA-221 promotes papillary thyroid carcinoma cells migration and invasion via targeting RECK and regulating epithelial–mesenchymal transition

Wei Z, Gao A, Wang Q, Lou X, Zhao J, Lu Q

OncoTargets and Therapy 2019, 12:2323-2333

Published Date: 28 March 2019

Original Research

Molecular subtype classification of papillary renal cell cancer using miRNA expression

Yu C, Dai D, Xie J

OncoTargets and Therapy 2019, 12:2311-2322

Published Date: 29 March 2019

Original Research

Development and validation of prognostic nomograms for medullary thyroid cancer

Guan Y, Fang S, Chen L, Li Z

OncoTargets and Therapy 2019, 12:2299-2309

Published Date: 27 March 2019

Original Research

TRIM31 promotes glioma proliferation and invasion through activating NF-κB pathway

Zhou L, Deng ZZ, Li HY, Jiang N, Wei ZS, Hong MF, Chen XD, Wang JH, Zhang MX, Shi YH, Lu ZQ, Huang XM

OncoTargets and Therapy 2019, 12:2289-2297

Published Date: 27 March 2019

Review

Management of recurrent Ewing sarcoma: challenges and approaches

Van Mater D, Wagner L

OncoTargets and Therapy 2019, 12:2279-2288

Published Date: 27 March 2019

Review

Selecting treatment options in refractory metastatic colorectal cancer

Byrne M, Saif MW

OncoTargets and Therapy 2019, 12:2271-2278

Published Date: 27 March 2019

Original Research

A novel curcumin derivative CL-6 exerts antitumor effect in human gastric cancer cells by inducing apoptosis through Hippo–YAP signaling pathway

Ye C, Wang W, Xia G, Yu C, Yi Y, Hua C, Tu F, Shen L, Chen C, Sun W, Zheng Z

OncoTargets and Therapy 2019, 12:2259-2269

Published Date: 27 March 2019

Original Research

MDM2 promotes epithelial–mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma

Tang Y, Xuan Y, Qiao G, Ou Z, He Z, Zhu Q, Liao M, Yin G

OncoTargets and Therapy 2019, 12:2247-2258

Published Date: 27 March 2019

Original Research

TRIB3 suppresses proliferation and invasion and promotes apoptosis of endometrial cancer cells by regulating the AKT signaling pathway

Qu J, Liu B, Li B, Du G, Li Y, Wang J, He L, Wan X

OncoTargets and Therapy 2019, 12:2235-2245

Published Date: 27 March 2019

Original Research

Effect of Th9/IL-9 on the growth of gastric cancer in nude mice

Cai L, Zhang Y, Zhang Y, Chen H, Hu J

OncoTargets and Therapy 2019, 12:2225-2234

Published Date: 26 March 2019

Original Research

The impact of adjuvant radiotherapy on molecular prognostic markers in gliomas

Harat M, Blok M, Harat A, Soszyńska K

OncoTargets and Therapy 2019, 12:2215-2224

Published Date: 26 March 2019

Original Research

Efficacy of on-demand intrahepatic arterial therapy in combination with sorafenib for advanced hepatocellular carcinoma

Tajiri K, Futsukaichi Y, Kobayashi S, Nagata K, Yasumura S, Takahara T, Minemura M, Yasuda I

OncoTargets and Therapy 2019, 12:2205-2214

Published Date: 26 March 2019

Original Research

LINC01296 promotes proliferation, migration, and invasion of HCC cells by targeting miR-122-5P and modulating EMT activity

Wan Y, Li M, Huang P

OncoTargets and Therapy 2019, 12:2193-2203

Published Date: 26 March 2019

Original Research

Delayed remission following sequential infusion of humanized CD19- and CD22-modified CAR-T cells in a patient with relapsed/refractory acute lymphoblastic leukemia and prior exposure to murine-derived CD19-directed CAR-T cells

Yang F, Zhang J, Zhang X, Tian M, Wang J, Kang L, Qiu H, Wu D

OncoTargets and Therapy 2019, 12:2187-2191

Published Date: 25 March 2019

Case report

A case of small-cell lung cancer with adrenocorticotropic hormone deficiency induced by nivolumab

Zhu Y, Wu HH, Wang W

OncoTargets and Therapy 2019, 12:2181-2186

Published Date: 25 March 2019

Original Research

The role of IRAK1 in breast cancer patients treated with neoadjuvant chemotherapy

Yang M, Qin X, Qin G, Zheng X

OncoTargets and Therapy 2019, 12:2171-2180

Published Date: 25 March 2019

Original Research

Weekly alternate intensive regimen FIrB/FOx in metastatic colorectal cancer patients: an update from clinical practice

Cortellini A, Cannita K, Parisi A, Lanfiuti Baldi P, Venditti O, D'Orazio C, Dal Mas A, Calvisi G, Giordano AV, Vicentini V, Vicentini R, Felicioni L, Marchetti A, Buttitta F, Russo A, Ficorella C

OncoTargets and Therapy 2019, 12:2159-2170

Published Date: 25 March 2019

Original Research

miR-1-3p suppresses proliferation of hepatocellular carcinoma through targeting SOX9

Zhang H, Zhang Z, Gao L, Qiao Z, Yu M, Yu B, Yang T

OncoTargets and Therapy 2019, 12:2149-2157

Published Date: 22 March 2019

Original Research

CDK7 inhibitor suppresses tumor progression through blocking the cell cycle at the G2/M phase and inhibiting transcriptional activity in cervical cancer

Zhong S, Zhang Y, Yin X, Di W

OncoTargets and Therapy 2019, 12:2137-2147

Published Date: 22 March 2019

Review

Research status and progress of the RNA or protein biomarkers for prostate cancer

Song C, Chen H, Song C

OncoTargets and Therapy 2019, 12:2123-2136

Published Date: 22 March 2019

Original Research

SUVmax and metabolic tumor volume: surrogate image biomarkers of KRAS mutation status in colorectal cancer

Lv Y, Wang X, Liang L, Wang L, Lu J

OncoTargets and Therapy 2019, 12:2115-2121

Published Date: 21 March 2019

Original Research

Elevated nuclear auto-antigenic sperm protein promotes melanoma progression by inducing cell proliferation

Li JX, Wei CY, Cao SG, Xia MW

OncoTargets and Therapy 2019, 12:2105-2113

Published Date: 21 March 2019

Original Research

Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer

Liu Z, Yu M, Fei B, Sun J, Wang D

OncoTargets and Therapy 2019, 12:2095-2104

Published Date: 20 March 2019

Case Series

Two cases of lymphangitic carcinomatosis as the primary symptom of colorectal carcinoma that achieved complete remission using combination anti-EGFR antibody therapy

Toshima H, Ikusue T, Hisamatsu A, Kobayashi K, Shimada K

OncoTargets and Therapy 2019, 12:2089-2093

Published Date: 20 March 2019

Original Research

Anti-PD1 up-regulates PD-L1 expression and inhibits T-cell lymphoma progression: possible involvement of an IFN-γ-associated JAK-STAT pathway

Xue W, Li W, Zhang T, Li Z, Wang Y, Qiu Y, Wang Y, Chen C, Fu D, Zhang M

OncoTargets and Therapy 2019, 12:2079-2088

Published Date: 19 March 2019

Original Research

Effect of 21-gene recurrence score in decision-making for surgery in early stage breast cancer

Wu SG, Zhang WW, Wang J, Dong Y, Chen YX, He ZY

OncoTargets and Therapy 2019, 12:2071-2078

Published Date: 19 March 2019

Original Research

Elevated expression of microRNA-328-3p suppresses aggressive malignant behaviors via targeting matrix metalloprotease 16 in osteosarcoma

Zhang M, Zhang J, Zhou Q

OncoTargets and Therapy 2019, 12:2063-2070

Published Date: 18 March 2019

Review

Spotlight on aldoxorubicin (INNO-206) and its potential in the treatment of soft tissue sarcomas: evidence to date

Cranmer LD

OncoTargets and Therapy 2019, 12:2047-2062

Published Date: 18 March 2019

Original Research

Paradoxical effects of cellular senescence-inhibited gene involved in hepatocellular carcinoma migration and proliferation by ERK pathway and mesenchymal-like markers

Cheng Q, Tong TJ, Li Z, Hu S, Chen D, Wang SQ, Zhu JY

OncoTargets and Therapy 2019, 12:2035-2046

Published Date: 15 March 2019

Original Research

Microcalcification and BMP-2 in breast cancer: correlation with clinicopathological features and outcomes

Zhang L, Hao C, Wu Y, Zhu Y, Ren Y, Tong Z

OncoTargets and Therapy 2019, 12:2023-2033

Published Date: 15 March 2019

Original Research

Curcumin inhibits the proliferation and invasion of MG-63 cells through inactivation of the p-JAK2/p-STAT3 pathway

Sun Y, Liu L, Wang Y, He A, Hu H, Zhang J, Han M, Huang Y

OncoTargets and Therapy 2019, 12:2011-2021

Published Date: 15 March 2019

Original Research

Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis

Shi W, Dong F, Jiang Y, Lu L, Wang C, Tan J, Yang W, Guo H, Ming J, Huang T

OncoTargets and Therapy 2019, 12:1979-2010

Published Date: 15 March 2019

Original Research

Downregulation of MMSET impairs breast cancer proliferation and metastasis through inhibiting Wnt/β-catenin signaling

Zhao X, Xie T, Zhao W, Cai W, Su X

OncoTargets and Therapy 2019, 12:1965-1977

Published Date: 14 March 2019

Original Research

Elevated apolipoprotein B predicts poor postsurgery prognosis in patients with hepatocellular carcinoma

Yan X, Yao M, Wen X, Zhu Y, Zhao E, Qian X, Chen X, Lu W, Lv Q, Zhang L, Lu F

OncoTargets and Therapy 2019, 12:1957-1964

Published Date: 12 March 2019

Original Research

Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin

Dong C, Liu X, Wang H, Li J, Dai L, Li J, Xu Z

OncoTargets and Therapy 2019, 12:1947-1956

Published Date: 12 March 2019

Review

Mechanisms of drug resistance in acute myeloid leukemia

Zhang J, Gu Y, Chen B

OncoTargets and Therapy 2019, 12:1937-1945

Published Date: 11 March 2019

Original Research

Long noncoding RNA STXBP5-AS1 inhibits cell proliferation, migration, and invasion through inhibiting the PI3K/AKT signaling pathway in gastric cancer cells

Cen D, Huang H, Yang L, Guo K, Zhang J

OncoTargets and Therapy 2019, 12:1929-1936

Published Date: 8 March 2019

Original Research

Prognostic implications and oncogenic roles of MYBL2 protein expression in esophageal squamous-cell carcinoma

Qin H, Li Y, Zhang H, Wang F, He H, Bai X, Li S

OncoTargets and Therapy 2019, 12:1917-1927

Published Date: 8 March 2019

Review

lncRNAs as potential molecular biomarkers in the clinicopathology and prognosis of cholangiocarcinoma: a systematic review and meta-analysis

Dai K, Quan J, Yan F, Jin X, Pan X, Song X, Zhang S, Ren Q, Liu J, Liu X

OncoTargets and Therapy 2019, 12:1905-1915

Published Date: 8 March 2019

Original Research

MACC1 promotes angiogenesis in cholangiocarcinoma by upregulating VEGFA

Peng T, Li Z, Li D, Wang S

OncoTargets and Therapy 2019, 12:1893-1903

Published Date: 8 March 2019

Original Research

Neoadjuvant chemotherapy with radical surgery vs radical surgery alone for cervical cancer: a systematic review and meta-analysis

Zhao H, He Y, Yang S, Zhao Q, Wu Y

OncoTargets and Therapy 2019, 12:1881-1891

Published Date: 7 March 2019

Original Research

ROS generation and autophagosome accumulation contribute to the DMAMCL-induced inhibition of glioma cell proliferation by regulating the ROS/MAPK signaling pathway and suppressing the Akt/mTOR signaling pathway

Wang Y, Zhang J, Yang Y, Liu Q, Xu G, Zhang R, Pang Q

OncoTargets and Therapy 2019, 12:1867-1880

Published Date: 7 March 2019

Review

Targeting off-target effects: endoplasmic reticulum stress and autophagy as effective strategies to enhance temozolomide treatment

He Y, Su J, Lan B, Gao Y, Zhao J

OncoTargets and Therapy 2019, 12:1857-1865

Published Date: 7 March 2019

Case report

A case report for severe hand–foot skin reaction caused by chemotherapy with actinomycin D in a patient with oculocutaneous albinism

Yan SJ, Li Y, Li ZL, Chen Y, Zhang XH, Xiao L

OncoTargets and Therapy 2019, 12:1851-1855

Published Date: 8 March 2019

Original Research

Lipid nanobubbles as an ultrasound-triggered artesunate delivery system for imaging-guided, tumor-targeted chemotherapy

Gao S, Cheng X, Li J

OncoTargets and Therapy 2019, 12:1841-1850

Published Date: 6 March 2019

Original Research

Ubiquitin-specific protease 4 promotes glioblastoma multiforme via activating ERK pathway

Zhou Y, Liang P, Ji W, Yu Z, Chen H, Jiang L

OncoTargets and Therapy 2019, 12:1825-1839

Published Date: 5 March 2019

Original Research

The overexpression of Rab9 promotes tumor progression regulated by XBP1 in breast cancer

Liu Y, Wang X, Zhang Z, Xiao B, An B, Zhang J

OncoTargets and Therapy 2019, 12:1815-1824

Published Date: 4 March 2019

Original Research

Elevated HOXA13 expression promotes the proliferation and metastasis of gastric cancer partly via activating Erk1/2

Qin Z, Chen Z, Weng J, Li S, Rong Z, Zhou C

OncoTargets and Therapy 2019, 12:1803-1813

Published Date: 4 March 2019

Original Research

A meta-analysis of the efficacy and safety of PD-1/PD-L1 immune checkpoint inhibitors as treatments for metastatic bladder cancer

Fan Z, Liang Y, Yang X, Li B, Cui L, Luo L, Jia Y, Wang Y, Niu H

OncoTargets and Therapy 2019, 12:1791-1801

Published Date: 4 March 2019

Review

Targeting Trop-2 in solid tumors: future prospects

Zaman S, Jadid H, Denson AC, Gray JE

OncoTargets and Therapy 2019, 12:1781-1790

Published Date: 1 March 2019

Original Research

Genetic ablation of TAZ induces HepG2 liver cancer cell apoptosis through activating the CaMKII/MIEF1 signaling pathway

Hou Y, Lan C, Kong Y, Zhu C, Peng W, Huang Z, Zhang C

OncoTargets and Therapy 2019, 12:1765-1779

Published Date: 1 March 2019

Original Research

Upregulated expression of ACTL8 contributes to invasion and metastasis and indicates poor prognosis in colorectal cancer

Han Q, Sun ML, Liu WS, Zhao HS, Jiang LY, Yu ZJ, Wei MJ

OncoTargets and Therapy 2019, 12:1749-1763

Published Date: 1 March 2019

Original Research

Single institution experience of split course radiotherapy in patients with desmoid tumors

Luo J, Jin K, Qian S, Ma X, Pan Z, Yao W, Zhang Z, Guo X, Yu X

OncoTargets and Therapy 2019, 12:1741-1748

Published Date: 7 March 2019

Original Research

Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function

Zhou L, Liu LL, Chai W, Zhao T, Jin X, Guo XX, Han LY, Yuan CL

OncoTargets and Therapy 2019, 12:1729-1739

Published Date: 28 February 2019

Original Research

Everolimus for the treatment of advanced gastrointestinal or lung nonfunctional neuroendocrine tumors in East Asian patients: a subgroup analysis of the RADIANT-4 study

Yao JC, Oh DY, Qian JM, Park YS, Herbst F, Ridolfi A, Izquierdo M, Ito T, Jia LQ, Komoto I, Sriuranpong V, Shimada Y

OncoTargets and Therapy 2019, 12:1717-1728

Published Date: 28 February 2019

Original Research

CD24 isoform a promotes cell proliferation, migration and invasion and is downregulated by EGR1 in hepatocellular carcinoma

Li L, Chen J, Ge C, Zhao F, Chen T, Tian H, Li J, Li H

OncoTargets and Therapy 2019, 12:1705-1716

Published Date: 28 February 2019

Original Research

RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma

Yan Y, Xu H, Zhang L, Zhou X, Qian X, Zhou J, Huang Y, Ge W, Wang W

OncoTargets and Therapy 2019, 12:1691-1703

Published Date: 28 February 2019

Original Research

Concurrent apatinib and docetaxel vs apatinib monotherapy as third- or subsequent-line therapy for advanced gastric adenocarcinoma: a retrospective study

Lin H, Han D, Fu G, Liu C, Wang L, Han S, Liu B, Yu J

OncoTargets and Therapy 2019, 12:1681-1689

Published Date: 28 February 2019

Original Research

Effects of various interventions on the occurrence of macrovascular invasion of hepatocellular carcinoma after the baseline serum γ-glutamyltransferase stratification

Liu Y, Zhang Q, Yang X, Li Y, Zhu B, Niu S, Huang Y, Hu Y, Wang X

OncoTargets and Therapy 2019, 12:1671-1679

Published Date: 28 February 2019

Original Research

Clinical utility of a novel natural killer cell activity assay for diagnosing non-small cell lung cancer: a prospective pilot study

Choi SI, Lee SH, Park JY, Kim KA, Lee EJ, Lee SY, In KH

OncoTargets and Therapy 2019, 12:1661-1669

Published Date: 27 February 2019

Original Research

The contribution of ABCG2 G34A and C421A polymorphisms to multiple myeloma susceptibility

Niebudek K, Balcerczak E, Mirowski M, Pietrzak J, Zawadzka I, Żebrowska-Nawrocka M

OncoTargets and Therapy 2019, 12:1655-1660

Published Date: 27 February 2019

Original Research

TCTP promotes epithelial–mesenchymal transition in lung adenocarcinoma

Sun R, Lu X, Gong L, Jin F

OncoTargets and Therapy 2019, 12:1641-1653

Published Date: 27 February 2019

Original Research

ARQ-197 enhances the antitumor effect of sorafenib in hepatocellular carcinoma cells via decelerating its intracellular clearance

Gao X, Chen H, Huang X, Li H, Liu Z, Bo X

OncoTargets and Therapy 2019, 12:1629-1640

Published Date: 26 February 2019

Original Research

Nab-paclitaxel in pretreated metastatic breast cancer: evaluation of activity, safety, and quality of life

De Luca R, Profita G, Cicero G

OncoTargets and Therapy 2019, 12:1621-1627

Published Date: 26 February 2019

Original Research

The accumulation of metabolic syndrome components is associated with higher risk of positive surgical margin among patients with localized prostate cancer after radical prostatectomy

Zheng X, Qiu S, Liao X, Han X, Jin K, Yang L, Wei Q

OncoTargets and Therapy 2019, 12:1613-1620

Published Date: 26 February 2019

Original Research

Ubiquitin-specific peptidase 28 enhances STAT3 signaling and promotes cell growth in non-small-cell lung cancer

Li P, Huang Z, Wang J, Chen W, Huang J

OncoTargets and Therapy 2019, 12:1603-1611

Published Date: 26 February 2019

Case report

Primary poorly differentiated small cell type neuroendocrine carcinoma of the hypopharynx

Ao YJ, Zhou SH

OncoTargets and Therapy 2019, 12:1593-1601

Published Date: 27 February 2019

Review

Management of recurrent nasopharyngeal carcinoma: current perspectives

Perri F, Della Vittoria Scarpati G, Caponigro F, Ionna F, Longo F, Buonopane S, Muto P, Di Marzo M, Pisconti S, Solla R

OncoTargets and Therapy 2019, 12:1583-1591

Published Date: 26 February 2019

Original Research

MLL3 promotes the senescence of esophageal squamous cell carcinoma

Xia M, Ling F, Gao F, Tao C

OncoTargets and Therapy 2019, 12:1575-1582

Published Date: 1 March 2019

Original Research

Deleted in breast cancer 1 as a potential prognostic biomarker in human cancers: a pooled analysis of 2,254 patients

Liu G, Wu Q, Wang Y, Xiong Q, Fu F

OncoTargets and Therapy 2019, 12:1563-1574

Published Date: 22 February 2019

Original Research

NACT + IMRT versus NACT + IMRT + CCRT in locoregionally advanced NPC patients: a retrospective study

Chen X, Zhu X, Wang J, Liu J, Ji R

OncoTargets and Therapy 2019, 12:1553-1562

Published Date: 22 February 2019

Review

Caveolin-1: a multifaceted driver of breast cancer progression and its application in clinical treatment

Qian XL, Pan YH, Huang QY, Shi YB, Huang QY, Hu ZZ, Xiong LX

OncoTargets and Therapy 2019, 12:1539-1552

Published Date: 27 February 2019

Review

Development of treatment options for Chinese patients with advanced squamous cell lung cancer: focus on afatinib

Lu S

OncoTargets and Therapy 2019, 12:1521-1538

Published Date: 22 February 2019

Original Research

Downregulation of KLF13 through DNMT1-mediated hypermethylation promotes glioma cell proliferation and invasion

Wu R, Yun Q, Zhang JP, Bao J

OncoTargets and Therapy 2019, 12:1509-1520

Published Date: 22 February 2019

Review

The surgical perspective in precision treatment of diffuse gliomas

Thon N, Tonn JC, Kreth FW

OncoTargets and Therapy 2019, 12:1497-1508

Published Date: 22 February 2019

Original Research

Sympathetic innervation contributes to perineural invasion of salivary adenoid cystic carcinoma via the β2-adrenergic receptor

Ma C, Gao T, Ju J, Zhang Y, Ni Q, Li Y, Zhao Z, Chai J, Yang X, Sun M

OncoTargets and Therapy 2019, 12:1475-1495

Published Date: 21 February 2019

Original Research

BRAF mutation in cytologically indeterminate thyroid nodules: after reclassification of a variant thyroid carcinoma

Pongsapich W, Chongkolwatana C, Poungvarin N, Amornpichetkul K, Piyawattayakorn N, Vejvisithsakul P, Maneeprasopchoke P

OncoTargets and Therapy 2019, 12:1465-1473

Published Date: 21 February 2019

Review

Spotlight on liposomal irinotecan for metastatic pancreatic cancer: patient selection and perspectives

Woo W, Carey ET, Choi M

OncoTargets and Therapy 2019, 12:1455-1463

Published Date: 21 February 2019

Original Research

IL-27 inhibits non-small-cell lung cancer cell metastasis by miR-935 in vitro

Wang T, Chen Y, Nie H, Huang Y, Zhao Y, Yang J

OncoTargets and Therapy 2019, 12:1447-1454

Published Date: 21 February 2019

Original Research

Impact of liver kinase B1 on p53 and survivin and its correlation with prognosis in gastric cancer

Li W, Luo S, Ma G, Wang L

OncoTargets and Therapy 2019, 12:1439-1445

Published Date: 22 February 2019

Case report

Multiple extramedullary plasmacytomas of the trachea and pharyngeal tissue: a case report and literature review

Tang R, Wang Y, Liang C, Li W, Pei L, Kang J, Hou G

OncoTargets and Therapy 2019, 12:1433-1437

Published Date: 20 February 2019

Original Research

Extracellular matrix protein 1 (ECM1) is associated with carcinogenesis potential of human bladder cancer

Wang Z, Zhou Q, Li A, Huang W, Cai Z, Chen W

OncoTargets and Therapy 2019, 12:1423-1432

Published Date: 20 February 2019

Review

First-line tyrosine kinase inhibitors in EGFR mutation-positive non-small-cell lung cancer: a network meta-analysis

Holleman MS, van Tinteren H, Groen HJM, Al MJ, Uyl-de Groot CA

OncoTargets and Therapy 2019, 12:1413-1421

Published Date: 20 February 2019

Original Research

Bioinformatic analysis of miR-4792 regulates Radix Tetrastigma hemsleyani flavone to inhibit proliferation, invasion, and induce apoptosis of A549 cells

Liu P, Pu J, Zhang J, Chen Z, Wei K, Shi L

OncoTargets and Therapy 2019, 12:1401-1412

Published Date: 20 February 2019

Case report

Merkel cell carcinoma metastatic to cervical lymph node in a patient with rheumatoid arthritis: a case report

Li N, Wang G, Jiang X, Huang M, Tian H, Xuan F, Zhang Y, Lv Y, Hu M, Wang Z, Ren P, Xu M

OncoTargets and Therapy 2019, 12:1395-1400

Published Date: 19 February 2019

Case Series

Brain metastases from breast cancer may respond to endocrine therapy: report of two cases

Wang Q, Sun B, Liu C, Shi S, Ding L, Liu J, Wu S

OncoTargets and Therapy 2019, 12:1389-1393

Published Date: 19 February 2019

Original Research

CT-guided cryoablation for unresectable pelvic recurrent colorectal cancer: a retrospective study

Wang Y, He XH, Xu LC, Huang HZ, Li GD, Wang YH, Li WT, Wang GZ

OncoTargets and Therapy 2019, 12:1379-1387

Published Date: 19 February 2019

Original Research

lncRNA MALAT1 potentiates the progression of tongue squamous cell carcinoma through regulating miR-140-5p-PAK1 pathway

Zhu M, Zhang C, Chen D, Chen S, Zheng H

OncoTargets and Therapy 2019, 12:1365-1377

Published Date: 19 February 2019

Case report

Stereotactic body radiation therapy for pulmonary large cell neuroendocrine carcinoma: a case report

Jo IY, Yeo SG

OncoTargets and Therapy 2019, 12:1359-1364

Published Date: 18 February 2019

Original Research

lncRNA SLCO4A1-AS1 promotes growth and invasion of bladder cancer through sponging miR-335-5p to upregulate OCT4

Yang Y, Wang F, Huang H, Zhang Y, Xie H, Men T

OncoTargets and Therapy 2019, 12:1351-1358

Published Date: 18 February 2019

Original Research

Irreversible electroporation combined with chemotherapy for unresectable pancreatic carcinoma: a prospective cohort study

Liu S, Qin Z, Xu J, Zeng J, Chen J, Niu L, Xu M

OncoTargets and Therapy 2019, 12:1341-1350

Published Date: 18 February 2019

Case report

Treatment of adult brainstem glioma with combined antiangiogenic therapy: a case report and literature review

Yu D, Han G, Liu H, Gao L, Verma V

OncoTargets and Therapy 2019, 12:1333-1339

Published Date: 18 February 2019

Original Research

Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis

Yang K, Gao J, Luo M

OncoTargets and Therapy 2019, 12:1319-1331

Published Date: 18 February 2019

Original Research

High expression of NUCB2 promotes papillary thyroid cancer cells proliferation and invasion

Zhao J, Yun X, Ruan X, Chi J, Yu Y, Li Y, Zheng X, Gao M

OncoTargets and Therapy 2019, 12:1309-1318

Published Date: 18 February 2019

Original Research

Potent in vitro and xenograft antitumor activity of a novel agent, PV-10, against relapsed and refractory neuroblastoma

Swift L, Zhang C, Trippett T, Narendran A

OncoTargets and Therapy 2019, 12:1293-1307

Published Date: 18 February 2019

Review

Ten years of research on the role of BVES/POPDC1 in human disease: a review

Han P, Lei Y, Li D, Liu J, Yan W, Tian D

OncoTargets and Therapy 2019, 12:1279-1291

Published Date: 18 February 2019

Original Research

Correlations of lncRNAs with cervical lymph node metastasis and prognosis of papillary thyroid carcinoma

Li N, Cui M, Yu P, Li Q

OncoTargets and Therapy 2019, 12:1269-1278

Published Date: 18 February 2019

Review

Moderate hypofractionated radiotherapy vs conventional fractionated radiotherapy in localized prostate cancer: a systemic review and meta-analysis from Phase III randomized trials

Yin Z, You J, Wang YY, Zhao J, Jiang S, Zhang X, Wang P, Tao Z, Wang X, Yuan Z

OncoTargets and Therapy 2019, 12:1259-1268

Published Date: 15 February 2019

Original Research

Upregulation of STC2 in colorectal cancer and its clinicopathological significance

Zhang C, Chen S, Ma X, Yang Q, Su F, Shu X, Xie W, Feng M, Xiong B

OncoTargets and Therapy 2019, 12:1249-1258

Published Date: 15 February 2019

Original Research

Optimal postoperative adjuvant treatment strategy for HBV-related hepatocellular carcinoma with microvascular invasion: a propensity score analysis

Wang L, Chen B, Li Z, Yao X, Liu M, Rong W, Wu F, Lin S, Liu Y, Zheng Y, Li Y, Wang W, Wu J

OncoTargets and Therapy 2019, 12:1237-1247

Published Date: 15 February 2019

Original Research

Knockdown of EIF3C promotes human U-2OS cells apoptosis through increased CAS P3/7 and Chk1/2 by upregulating SAPK/JNK

Gao WL, Hu Y, Zhang ZQ, Du GW, Yin L, Yin ZS

OncoTargets and Therapy 2019, 12:1225-1235

Published Date: 14 February 2019

Original Research

Combined silencing of VEGF-A and angiopoietin-2, a more effective way to inhibit the Ishikawa endometrial cancer cell line

Xu X, Yan Y, Xun Q, Shi J, Kong X, Wu J, Zhou H

OncoTargets and Therapy 2019, 12:1215-1223

Published Date: 14 February 2019

Original Research

PNUTS mediates ionizing radiation-induced CNE-2 nasopharyngeal carcinoma cell migration, invasion, and epithelial–mesenchymal transition via the PI3K/AKT signaling pathway

Yu D, An X, Fan W, Wang X, He Y, Li B

OncoTargets and Therapy 2019, 12:1205-1214

Published Date: 15 February 2019

Review

Metabolic reprogramming results in abnormal glycolysis in gastric cancer: a review

Liu Y, Zhang Z, Wang J, Chen C, Tang X, Zhu J, Liu J

OncoTargets and Therapy 2019, 12:1195-1204

Published Date: 13 February 2019

Original Research

Dicerandrol B: a natural xanthone dimer induces apoptosis in cervical cancer HeLa cells through the endoplasmic reticulum stress and mitochondrial damage

Gao DD, Guo ZM, Wang JB, Hu GF, Su YQ, Chen LJ, Lv QW, Yu HM, Qin JC, Xu W

OncoTargets and Therapy 2019, 12:1185-1193

Published Date: 13 February 2019

Case report

Rapid and complete response to idelalisib in a case of Richter syndrome

Bagacean C, Zdrenghea M, Saad H, Berthou C, Renaudineau Y, Tempescul A

OncoTargets and Therapy 2019, 12:1181-1184

Published Date: 13 February 2019

Original Research

Up-regulation of CKAP2L expression promotes lung adenocarcinoma invasion and is associated with poor prognosis

Xiong GS, Li LY, Chen XB, Song SN, Zhao YP, Cai WK, Peng JP

OncoTargets and Therapy 2019, 12:1171-1180

Published Date: 12 February 2019

Original Research

High-intensity focused ultrasound enhances the effect of bufalin by inducing apoptosis in pancreatic cancer cells

Ning Z, Zhu Z, Wang H, Zhang C, Xu L, Zhuang L, Yan X, Wang D, Wang P, Meng Z

OncoTargets and Therapy 2019, 12:1161-1170

Published Date: 12 February 2019

Original Research

Mst1-Hippo pathway triggers breast cancer apoptosis via inducing mitochondrial fragmentation in a manner dependent on JNK–Drp1 axis

Ouyang H, Zhou E, Wang H

OncoTargets and Therapy 2019, 12:1147-1159

Published Date: 11 February 2019

Original Research

Epstein-Barr virus-encoded LMP1 regulated Pim1 kinase expression promotes nasopharyngeal carcinoma cells proliferation

Ding R, Yuan J, Jia Y, Liao X, Wang S, Shao Z, Feng M, Jie W, Shen Z

OncoTargets and Therapy 2019, 12:1137-1146

Published Date: 11 February 2019

Original Research

Prognostic implications of MYBL2 in resected Chinese gastric adenocarcinoma patients

Jia YX, Gao YP, Li J, Chang ZW, Yan J, Qin YR

OncoTargets and Therapy 2019, 12:1129-1135

Published Date: 11 February 2019

Original Research

Extracellular Hsp90α clinically correlates with tumor malignancy and promotes migration and invasion in esophageal squamous cell carcinoma

Wang X, An D, Wang X, Liu X, Li B

OncoTargets and Therapy 2019, 12:1119-1128

Published Date: 11 February 2019

Original Research

Overexpression of shugoshin1 predicts a poor prognosis for prostate cancer and promotes metastasis by affecting epithelial–mesenchymal transition

Mu J, Fan L, Liu D, Zhu D

OncoTargets and Therapy 2019, 12:1111-1118

Published Date: 8 February 2019

Original Research

Expression of Lin28 is correlated with prognosis and expression of HER-2 and steroid receptors in breast cancer

Xu C, Jin S, Huang L

OncoTargets and Therapy 2019, 12:1105-1110

Published Date: 8 February 2019

Review

First-line treatment of women with advanced ovarian cancer: focus on bevacizumab

Marchetti C, Muzii L, Romito A, Benedetti Panici P

OncoTargets and Therapy 2019, 12:1095-1103

Published Date: 8 February 2019

Review

Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma

Ollila TA, Sahin I, Olszewski AJ

OncoTargets and Therapy 2019, 12:1085-1094

Published Date: 7 February 2019

Original Research

CHFR promotes the migration of human gastric cancer cells by inducing epithelial-to-mesenchymal transition in a HDAC1-dependent manner

Yang S, He F, Dai M, Pan J, Wang J, Ye B

OncoTargets and Therapy 2019, 12:1075-1084

Published Date: 7 February 2019

Case report

NCOA1–ALK: a novel ALK rearrangement in one lung adenocarcinoma patient responding to crizotinib treatment

Cao Q, Liu Z, Huang Y, Qi C, Yin X

OncoTargets and Therapy 2019, 12:1071-1074

Published Date: 7 February 2019

Original Research

Long noncoding RNA GIHCG induces cancer progression and chemoresistance and indicates poor prognosis in colorectal cancer

Jiang X, Li Q, Zhang S, Song C, Zheng P

OncoTargets and Therapy 2019, 12:1059-1070

Published Date: 7 February 2019

Original Research

Overexpressed long noncoding RNA TUG1 affects the cell cycle, proliferation, and apoptosis of pancreatic cancer partly through suppressing RND3 and MT2A

Hui B, Xu Y, Zhao B, Ji H, Ma Z, Xu S, He Z, Wang K, Lu J

OncoTargets and Therapy 2019, 12:1043-1057

Published Date: 5 February 2019

Retraction

The lncRNA TUG1 promotes epithelial ovarian cancer cell proliferation and invasion via the WNT/β-catenin pathway [Retraction]

Liu S, Liu Y, Lu Q, Zhou X, Chen L, Liang W

OncoTargets and Therapy 2019, 12:1041-1042

Published Date: 4 February 2019

Original Research

ZNF433 positively regulates the beta-catenin/TCF pathway in prostate cancer and enhances the tumorigenicity of cancer cells

Gu S, Hou P, Liu K, Niu X, Wei B, Mao F, Xu Z

OncoTargets and Therapy 2019, 12:1031-1039

Published Date: 1 February 2019

Original Research

HIFU is safe, effective, and feasible in pancreatic cancer patients: a monocentric retrospective study among 523 patients

Ning Z, Xie J, Chen Q, Zhang C, Xu L, Song L, Meng Z

OncoTargets and Therapy 2019, 12:1021-1029

Published Date: 1 February 2019

Original Research

Downregulated expression of RACK1 results in pancreatic cancer growth and metastasis

Zhang L, Lv Y, Rong Y, Chen W, Fang Y, Mao W, Lou W, Jin D, Xu X

OncoTargets and Therapy 2019, 12:1007-1020

Published Date: 1 February 2019

Original Research

Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer

Xiong Y, Zhou L, Su Z, Song J, Sun Q, Liu SS, Xia Y, Wang Z, Lu D

OncoTargets and Therapy 2019, 12:993-1005

Published Date: 5 February 2019

Original Research

Hypertension as a predictive biomarker in patients with advanced non-small-cell lung cancer treated with apatinib

Fang SC, Huang W, Zhang YM, Zhang HT, Xie WP

OncoTargets and Therapy 2019, 12:985-992

Published Date: 1 February 2019

Original Research

miR-135a suppresses migration of gastric cancer cells by targeting TRAF5-mediated NF-κB activation

Xie Y, Li F, Li Z, Shi Z

OncoTargets and Therapy 2019, 12:975-984

Published Date: 1 February 2019

Original Research

Efficacy and safety of targeted therapy for metastatic HER2-positive breast cancer in the first-line treatment: a Bayesian network meta-analysis

Feng F, Zhang T, Yin F, Liu C, Zhuang J, Qi L, Wang X, Li J, Wang L, Tian J, Sun C

OncoTargets and Therapy 2019, 12:959-974

Published Date: 31 January 2019

Case report

The coexistence of a Wilms’ tumor and renal cell carcinoma in children: a case report and review of the literature

Zou XP, Jiang YY, Liao Y, Dang YW, Chen G, Feng ZB, Ma Y

OncoTargets and Therapy 2019, 12:953-958

Published Date: 30 January 2019

Original Research

The expression of special AT-rich binding protein 1 in cervical cancer and its clinical significance

Zhao L, Zheng Y, Ji Y, Zhang X

OncoTargets and Therapy 2019, 12:945-951

Published Date: 30 January 2019

Original Research

Effects of combined inhibition of STAT3 and VEGFR2 pathways on the radiosensitivity of non-small-cell lung cancer cells

Hu C, Zhuang W, Qiao Y, Liu B, Liu L, Hui K, Jiang X

OncoTargets and Therapy 2019, 12:933-944

Published Date: 29 January 2019

Original Research

Establishing a detection method for CCNY: a potentially significant clinical investigative marker in NSCLC patients

Ma L, Gu M, Teng Y, Li W

OncoTargets and Therapy 2019, 12:921-932

Published Date: 29 January 2019

Original Research

microRNA-628 inhibits the proliferation of acute myeloid leukemia cells by directly targeting IGF-1R

Chen L, Jiang X, Chen H, Han Q, Liu C, Sun M

OncoTargets and Therapy 2019, 12:907-919

Published Date: 29 January 2019

Original Research

Reversing platinum resistance in ovarian cancer multicellular spheroids by targeting Bcl-2

Yang Y, Li S, Sun Y, Zhang D, Zhao Z, Liu L

OncoTargets and Therapy 2019, 12:897-906

Published Date: 29 January 2019

Original Research

Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation

Ji Y, Liu Y, Xue N, Du T, Wang L, Huang R, Li L, Yan C, Chen X

OncoTargets and Therapy 2019, 12:883-896

Published Date: 29 January 2019

Original Research

Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1

Wang J, Li H, Xia C, Yang X, Dai B, Tao K, Dou K

OncoTargets and Therapy 2019, 12:869-882

Published Date: 29 January 2019

Original Research

Efficacy and safety of nivolumab for metastatic biliary tract cancer

Gou M, Zhang Y, Si H, Dai G

OncoTargets and Therapy 2019, 12:861-867

Published Date: 25 January 2019

Original Research

MiR–206 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting the MUC1 gene

Deng M, Qin Y, Chen X, Wang Q, Wang J

OncoTargets and Therapy 2019, 12:849-859

Published Date: 25 January 2019

Original Research

miRNA-101-5p inhibits the growth and aggressiveness of NSCLC cells through targeting CXCL6

Chen Q, Liu D, Hu Z, Luo C, Zheng SL

OncoTargets and Therapy 2019, 12:835-848

Published Date: 25 January 2019

Original Research

The inhibitive effect of sh-HIF1A-AS2 on the proliferation, invasion, and pathological damage of breast cancer via targeting miR-548c-3p through regulating HIF-1α/VEGF pathway in vitro and vivo

Guo X, Lee S, Cao P

OncoTargets and Therapy 2019, 12:825-834

Published Date: 24 January 2019

Original Research

Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma

Wang L, Liu Y, Yu G

OncoTargets and Therapy 2019, 12:815-823

Published Date: 24 January 2019

Original Research

lncRNA small nucleolar RNA host gene 20 predicts poor prognosis in glioma and promotes cell proliferation by silencing P21

Li XS, Shen FZ, Huang LY, Hui L, Liu RH, Ma YJ, Jin BZ

OncoTargets and Therapy 2019, 12:805-814

Published Date: 24 January 2019

Original Research

MicroRNA-505 suppresses gastric cancer cell proliferation and invasion by directly targeting Polo-like kinase-1

Dang SC, Wang F, Qian XB, Abdul M, Naseer QA, Jin W, Hu R, Gu Q, Gu M

OncoTargets and Therapy 2019, 12:795-803

Published Date: 24 January 2019

Original Research

G-protein-signaling modulator 2 expression and role in a CD133+ pancreatic cancer stem cell subset

Dang SC, Qian XB, Jin W, Cui L, Chen JX, Gu M

OncoTargets and Therapy 2019, 12:785-794

Published Date: 23 January 2019

Original Research

Fenofibrate potentiates chemosensitivity to human breast cancer cells by modulating apoptosis via AKT/NF-κB pathway

Sun J, Zheng Z, Chen Q, Pan Y, Quan M, Dai Y

OncoTargets and Therapy 2019, 12:773-783

Published Date: 23 January 2019

Original Research

MicroRNA-217 acts as a tumor suppressor and correlates with the chemoresistance of cervical carcinoma to cisplatin

Yin Z, Ren W

OncoTargets and Therapy 2019, 12:759-771

Published Date: 23 January 2019

Case report

Radiotherapy in advanced glottic laryngeal carcinoma in a patient with Wegener’s granulomatosis: how much radiation dose is needed?

Lazzari G, Briatico Vangosa A, De Cillis MA, Silvano G

OncoTargets and Therapy 2019, 12:753-757

Published Date: 23 January 2019

Perspectives

miR-124, a potential therapeutic target in colorectal cancer

Qin Z, Liu X

OncoTargets and Therapy 2019, 12:749-751

Published Date: 22 January 2019

Case report

Acquisition of T790M resistance mutation in a patient with advanced adenocarcinoma harboring uncommon EGFR mutations: a case report and literature review

Hakozaki T, Yomota M

OncoTargets and Therapy 2019, 12:745-748

Published Date: 22 January 2019

Review

Comparison of neoadjuvant therapy and upfront surgery in resectable pancreatic cancer: a meta-analysis and systematic review

Ren X, Wei X, Ding Y, Qi F, Zhang Y, Hu X, Qin C, Li X

OncoTargets and Therapy 2019, 12:733-744

Published Date: 22 January 2019

Original Research

Anticancer activity of 1, 25-(OH)2D3 against human breast cancer cell lines by targeting Ras/MEK/ERK pathway

Zheng W, Cao L, Ouyang L, Zhang Q, Duan B, Zhou W, Chen S, Peng W, Xie Y, Fan Q, Gong D

OncoTargets and Therapy 2019, 12:721-732

Published Date: 22 January 2019

Original Research

Combining data from TCGA and GEO databases and reverse transcription quantitative PCR validation to identify gene prognostic markers in lung cancer

Liu X, Wang J, Chen M, Liu S, Yu X, Wen F

OncoTargets and Therapy 2019, 12:709-720

Published Date: 21 January 2019

Original Research

LncRNA SNHG16 drives proliferation and invasion of papillary thyroid cancer through modulation of miR-497

Wen Q, Zhao L, Wang T, Lv N, Cheng X, Zhang G, Bai L

OncoTargets and Therapy 2019, 12:699-708

Published Date: 18 January 2019

Original Research

Expression of NR1H3 in endometrial carcinoma and its effect on the proliferation of Ishikawa cells in vitro

Fang F, Li D, Zhao L, Li Y, Zhang T, Cui B

OncoTargets and Therapy 2019, 12:685-697

Published Date: 18 January 2019

Review

Role of radiotherapy in the treatment of metastatic head and neck cancer

Ordoñez R, Otero A, Jerez I, Medina JA, Lupiañez-Pérez Y, Gomez-Millan J

OncoTargets and Therapy 2019, 12:677-683

Published Date: 18 January 2019

Original Research

Comparing short-time outcomes of three-dimensional and two-dimensional totally laparoscopic surgery for colon cancer using overlapped delta-shaped anastomosis

Su H, Jin W, Wang P, Bao M, Wang X, Zhao C, Wang X, Zhou Z, Zhou H

OncoTargets and Therapy 2019, 12:669-675

Published Date: 18 January 2019

Original Research

The lncRNA ZEB2-AS1 is upregulated in gastric cancer and affects cell proliferation and invasion via miR-143-5p/HIF-1α axis

Wu F, Gao H, Liu K, Gao B, Ren H, Li Z, Liu F

OncoTargets and Therapy 2019, 12:657-667

Published Date: 18 January 2019

Original Research

Long non-coding RNA LINC00662 promotes proliferation and migration in oral squamous cell carcinoma

Xu D, Chen Y, Yuan C, Zhang S, Peng W

OncoTargets and Therapy 2019, 12:647-656

Published Date: 18 January 2019

Review

Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies

Tan FH, Putoczki TL, Stylli SS, Luwor RB

OncoTargets and Therapy 2019, 12:635-645

Published Date: 18 January 2019

Original Research

RAP80 expression in breast cancer and its relationship with apoptosis in breast cancer cells

Jin GH, Mao X, Qiao Z, Chen B, Jin F

OncoTargets and Therapy 2019, 12:625-634

Published Date: 18 January 2019

Case report

Ureteral metastasis of non-small-cell lung cancer: a case report

Ren F, Liu M, Xu X, Zhang H, Li X, Liu J, Chen J

OncoTargets and Therapy 2019, 12:619-623

Published Date: 15 January 2019

Original Research

Pharmacological inhibition of USP7 promotes antitumor immunity and contributes to colon cancer therapy

Fu C, Zhu X, Xu P, Li Y

OncoTargets and Therapy 2019, 12:609-617

Published Date: 15 January 2019

Original Research

miR-4262, low level of which predicts poor prognosis, targets proto-oncogene CD163 to suppress cell proliferation and invasion in gastric cancer

Zhang H, Jiang H, Zhang H, Liu J, Hu X, Chen L

OncoTargets and Therapy 2019, 12:599-607

Published Date: 15 January 2019

Original Research

Scutellarin inhibits the metastasis and cisplatin resistance in glioma cells

Tang S, Gao Y, Hu W

OncoTargets and Therapy 2019, 12:587-598

Published Date: 15 January 2019

Original Research

Effect of CD44st and HER2 expression on the postoperative prognosis of breast cancer patients

Chen DD, Ji JA, Yan HC, Huang GH, Fang XJ

OncoTargets and Therapy 2019, 12:577-585

Published Date: 15 January 2019

Original Research

Comprehensive analysis of potential prognostic genes for the construction of a competing endogenous RNA regulatory network in hepatocellular carcinoma

Yue C, Ren Y, Ge H, Liang C, Xu Y, Li G, Wu J

OncoTargets and Therapy 2019, 12:561-576

Published Date: 14 January 2019

Review

Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies

Xue B, Zhao J, Feng P, Xing J, Wu H, Li Y

OncoTargets and Therapy 2019, 12:549-559

Published Date: 11 January 2019

Original Research

Should we apply sorafenib in hepatocellular carcinoma patients with microvascular invasion after curative hepatectomy?

Huang Y, Zhang Z, Zhou Y, Yang J, Hu K, Wang Z

OncoTargets and Therapy 2019, 12:541-548

Published Date: 11 January 2019

Case report

Merkel cell carcinoma of the thigh: case report and review of the literature

Jiang W, Xu J, Wang R, Wang T, Shu Y, Liu L

OncoTargets and Therapy 2019, 12:535-540

Published Date: 11 January 2019

Original Research

Clinical significance of miR-195 in hepatocellular carcinoma and its biological function in tumor progression

Chen X, Wang A

OncoTargets and Therapy 2019, 12:527-534

Published Date: 10 January 2019

Original Research

Correlation between high-resolution computed tomography lung nodule characteristics and EGFR mutation in lung adenocarcinomas

Nie Y, Liu H, Tan X, Wang H, Li F, Li C, Han P, Lyv X, Xu X, Guo M

OncoTargets and Therapy 2019, 12:519-526

Published Date: 10 January 2019

Original Research

Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling

Jiang Z, Cao Q, Dai G, Wang J, Liu C, Lv L, Pan J

OncoTargets and Therapy 2019, 12:509-518

Published Date: 9 January 2019

Original Research

Long noncoding RNA UCA1 targets miR-582-5p and contributes to the progression and drug resistance of bladder cancer cells through ATG7-mediated autophagy inhibition

Wu J, Li W, Ning J, Yu W, Rao T, Cheng F

OncoTargets and Therapy 2019, 12:495-508

Published Date: 9 January 2019

Review

Diagnostic significance of miR-210 as a potential tumor biomarker of human cancer detection: an updated pooled analysis of 30 articles

Feng S, He A, Wang D, Kang B

OncoTargets and Therapy 2019, 12:479-493

Published Date: 9 January 2019

Original Research

The anthelmintic drug flubendazole induces cell apoptosis and inhibits NF-κB signaling in esophageal squamous cell carcinoma

Tao J, Zhao H, Xie X, Luo M, Gao Z, Sun H, Huang Z

OncoTargets and Therapy 2019, 12:471-478

Published Date: 9 January 2019

Original Research

Diagnostic value of multiple tumor-associated autoantibodies in lung cancer

Zhang R, Ma L, Li W, Zhou S, Xu S

OncoTargets and Therapy 2019, 12:457-469

Published Date: 9 January 2019

Original Research

Nodal staging score and adequacy of nodal staging

Chen H, Feng G

OncoTargets and Therapy 2019, 12:449-455

Published Date: 8 January 2019

Case report

Complete response with fluorouracil and irinotecan with a BRAFV600E and EGFR inhibitor in BRAF-mutated metastatic colorectal cancer: a case report

Wang Z, Dai WP, Zang YS

OncoTargets and Therapy 2019, 12:443-447

Published Date: 8 January 2019

Original Research

miR-302 cluster inhibits angiogenesis and growth of K562 leukemia cells by targeting VEGFA

Cao J, Li L, Han X, Cheng H, Chen W, Qi K, Chen C, Wu Q, Niu M, Zeng L, Xu K

OncoTargets and Therapy 2019, 12:433-441

Published Date: 8 January 2019

Original Research

lncRNA CASC9 regulates cell migration and invasion in hemangioma endothelial cells by targeting miR-125a-3p/Nrg1

Li X, Chen B, Chi D, Zhang Y, Jiang W

OncoTargets and Therapy 2019, 12:423-432

Published Date: 7 January 2019

Original Research

Long noncoding RNA SNHG16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p

Ye J, Zhang R, Du X, Chai W, Zhou Q

OncoTargets and Therapy 2019, 12:415-422

Published Date: 4 January 2019

Corrigendum

PLK1 as a potential prognostic marker of gastric cancer through MEK-ER K pathway on PDTX models [Corrigendum]

Dang SC, Fan YY, Cui L, Chen JX, Qu JG, Gu M

OncoTargets and Therapy 2019, 12:413-414

Published Date: 3 January 2019

Original Research

rs187960998 polymorphism in miR-211 prevent development of human colon cancer by deregulation of 3’UTR in CHD5

Zhu L, Wang R, Zhang L, Zuo C, Zhang R, Zhao S

OncoTargets and Therapy 2019, 12:405-412

Published Date: 3 January 2019

Original Research

TRIM28 activates autophagy and promotes cell proliferation in glioblastoma

Peng Y, Zhang M, Jiang Z, Jiang Y

OncoTargets and Therapy 2019, 12:397-404

Published Date: 3 January 2019

Review

CART cell therapy for prostate cancer: status and promise

Pan J, Guo Z, Yang C, Mao L

OncoTargets and Therapy 2019, 12:391-395

Published Date: 3 January 2019

Original Research

Targeted neoadjuvant therapy in the HER-2-positive breast cancer patients: a systematic review and meta-analysis

Ma W, Zhao F, Zhou C, Zhang Y, Zhao Y, Li N, Xie P

OncoTargets and Therapy 2019, 12:379-390

Published Date: 3 January 2019

Review

The progression of HMGB1-induced autophagy in cancer biology

Xu T, Jiang L, Wang Z

OncoTargets and Therapy 2019, 12:365-377

Published Date: 31 December 2018

Original Research

Serum cytoskeleton-associated protein 4 as a biomarker for the diagnosis of hepatocellular carcinoma

Wang Y, Yu W, He M, Huang Y, Wang M, Zhu J

OncoTargets and Therapy 2019, 12:359-364

Published Date: 31 December 2018

Original Research

Comparison of the diagnostic performance of fluorescence in situ hybridization (FISH), nuclear matrix protein 22 (NMP22), and their combination model in bladder carcinoma detection: a systematic review and meta-analysis

Liang Q, Zhang G, Li W, Wang J, Sheng S

OncoTargets and Therapy 2019, 12:349-358

Published Date: 31 December 2018

Original Research

Combination of TPF regimen and cinobufotalin inhibits proliferation and induces apoptosis in human hypopharyngeal and laryngeal squamous cell carcinoma cells

Shen X, Tao Y, Yang Y, Wang R, Fang J, Lian M

OncoTargets and Therapy 2019, 12:341-348

Published Date: 31 December 2018

Review

Toward fully exploiting the therapeutic potential of marketed pharmaceuticals: the use of octreotide and chloroquine in oncology

Papanagnou P, Papadopoulos GE, Stivarou T, Pappas A

OncoTargets and Therapy 2019, 12:319-339

Published Date: 31 December 2018

Original Research

MiR-6991-3p is identified as a novel suppressor in the expansion and activation of myeloid-derived suppressor cells in hepatoma-bearing mice

Sun JP, Ge QX, Ren Z, Sun XF, Xie SP

OncoTargets and Therapy 2019, 12:309-317

Published Date: 28 December 2018

Review

Evaluating ivosidenib for the treatment of relapsed/refractory AML: design, development, and place in therapy

Nassereddine S, Lap CJ, Tabbara IA

OncoTargets and Therapy 2019, 12:303-308

Published Date: 28 December 2018

Original Research

Contribution of FPR and TLR9 to hypoxia-induced chemoresistance of ovarian cancer cells

Cai Y, Huang J, Xing H, Li B, Li L, Wang X, Peng D, Chen J

OncoTargets and Therapy 2019, 12:291-301

Published Date: 28 December 2018

Original Research

CD4+ CD25+ regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial–mesenchymal transition

Shi C, Chen Y, Chen Y, Yang Y, Bing W, Qi J

OncoTargets and Therapy 2019, 12:279-289

Published Date: 28 December 2018

Original Research

Should S-1 be better than capecitabine for patients with advanced gastric cancer in Asia? A systematic review and meta-analysis

Ye Z, Chen J, Rao Y, Yang W

OncoTargets and Therapy 2019, 12:269-277

Published Date: 27 December 2018

Original Research

Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

Guo Q, Liu Y, Zhao J, Wang J, Li Y, Pang Y, Chen J, Wang J

OncoTargets and Therapy 2019, 12:257-267

Published Date: 27 December 2018

Erratum

Circ-DLG 1 promotes the proliferation of esophageal squamous cell carcinoma [Erratum]

Rong J, Wang Q, Zhang Y, Zhu D, Sun H, Tang W, Wang R, Shi W, Cao XF

OncoTargets and Therapy 2019, 12:255-256

Published Date: 27 December 2018

Original Research

Upregulation of valosin-containing protein (VCP) is associated with poor prognosis and promotes tumor progression of orbital B-cell lymphoma

Zhu W, Li D, Xiao L

OncoTargets and Therapy 2019, 12:243-253

Published Date: 27 December 2018

Original Research

DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells

Yang C, Li D, Bai Y, Song S, Yan P, Wu R, Zhang Y, Hu G, Lin C, Li X, Huang L

OncoTargets and Therapy 2019, 12:233-241

Published Date: 28 December 2018

Original Research

The use of regorafenib for patients with refractory metastatic colorectal cancer in clinical practice

Yoon SE, Lee SJ, Lee J, Park SH, Park JO, Lim HY, Kang WK, Park YS, Kim ST

OncoTargets and Therapy 2019, 12:225-231

Published Date: 24 December 2018

Original Research

CUX2 functions as an oncogene in papillary thyroid cancer

Sun Y, Ye D, Li Y, Chen E, Hao R, Cai Y, Wang Q, Wang O, Zhang X

OncoTargets and Therapy 2019, 12:217-224

Published Date: 24 December 2018

Original Research

miR-125a restrains cell migration and invasion by targeting STAT3 in gastric cancer cells

Yang L, Zhang S, Guo K, Huang H, Qi S, Yao J, Zhang Z

OncoTargets and Therapy 2019, 12:205-215

Published Date: 24 December 2018

Review

Critical factors in chimeric antigen receptor-modified T-cell (CAR-T) therapy for solid tumors

Yan LL, Liu BN

OncoTargets and Therapy 2019, 12:193-204

Published Date: 24 December 2018

Original Research

The diagnostic accuracy of liquid exosomes for lung cancer detection: a meta-analysis

Song Z, Wang S, Liu Y

OncoTargets and Therapy 2019, 12:181-192

Published Date: 24 December 2018

Original Research

LncRNA SNHG5 promotes growth and invasion in melanoma by regulating the miR-26a-5p/TRPC3 pathway

Gao J, Zeng K, Liu Y, Gao L, Liu L

OncoTargets and Therapy 2019, 12:169-179

Published Date: 24 December 2018

Original Research

Analysis of long non-coding RNAs in glioblastoma for prognosis prediction using weighted gene co-expression network analysis, Cox regression, and L1-LASSO penalization

Liang R, Zhi YQ, Zheng G, Zhang B, Zhu H, Wang M

OncoTargets and Therapy 2019, 12:157-168

Published Date: 21 December 2018

Original Research

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro

Hu S, Xu L, Li L, Luo D, Zhao H, Li D, Peng B

OncoTargets and Therapy 2019, 12:147-156

Published Date: 21 December 2018

Original Research

Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression

Guo L, Gu J, Hou S, Liu D, Zhou M, Hua T, Zhang J, Ge Z, Xu J

OncoTargets and Therapy 2019, 12:135-146

Published Date: 21 December 2018

Original Research

RASSF1A promoter methylation correlates development, progression, and poor cancer-specific survival of renal cell carcinoma: trial sequential analysis

Zhuang Q, Chen Z, Shen J, Fan M, Xue D, Lu H, Xu R, He X

OncoTargets and Therapy 2019, 12:119-134

Published Date: 20 December 2018

Case report

Individualized treatment for a case of recurrent ovarian ependymoma

Yuan Z, Yu M, Chen Y

OncoTargets and Therapy 2019, 12:113-117

Published Date: 20 December 2018

Original Research

Long noncoding RNA SNHG15 serves as an oncogene and predicts poor prognosis in epithelial ovarian cancer

Qu C, Dai C, Guo Y, Qin R, Liu J

OncoTargets and Therapy 2019, 12:101-111

Published Date: 19 December 2018

Original Research

Tanshinol inhibits the growth, migration and invasion of hepatocellular carcinoma cells via regulating the PI3K-AKT signaling pathway

Zhu P, Liu Z, Zhou J, Chen Y

OncoTargets and Therapy 2019, 12:87-99

Published Date: 19 December 2018

Original Research

Long noncoding RNA LINC01296 promotes cancer-cell proliferation and metastasis in urothelial carcinoma of the bladder

Wang X, Wang L, Gong Y, Liu Z, Qin Y, Chen J, Li N

OncoTargets and Therapy 2019, 12:75-85

Published Date: 19 December 2018

Original Research

Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma

Cao JX, Lu Y

OncoTargets and Therapy 2019, 12:63-74

Published Date: 20 December 2018

Case report

Use of anlotinib in intra-abdominal desmoplastic small round cell tumors: a case report and literature review

Chen HM, Feng G

OncoTargets and Therapy 2019, 12:57-61

Published Date: 18 December 2018

Case report

Newly emergent acquired EGFR exon 18 G724S mutation after resistance of a T790M specific EGFR inhibitor osimertinib in non-small-cell lung cancer: a case report

Zhang Y, He B, Zhou D, Li M, Hu C

OncoTargets and Therapy 2019, 12:51-56

Published Date: 18 December 2018

Original Research

MicroRNA-562 negatively regulated c-MET/AKT pathway in the growth of glioblastoma cells

Nie X, Su Z, Yan R, Yan A, Qiu S, Zhou Y

OncoTargets and Therapy 2019, 12:41-49

Published Date: 21 December 2018

Original Research

Upregulation of syncytin-1 promotes invasion and metastasis by activating epithelial-mesenchymal transition-related pathway in endometrial carcinoma

Liu C, Xu J, Wen F, Yang F, Li X, Geng D, Li L, Chen J, Zheng J

OncoTargets and Therapy 2019, 12:31-40

Published Date: 17 December 2018

Original Research

Methotrexate-induced apoptosis in human ovarian adenocarcinoma SKOV-3 cells via ROS-mediated bax/bcl-2-cyt-c release cascading

AlBasher G, AlKahtane AA, Alarifi S, Ali D, Alessia MS, Almeer RS, Abdel-Daim MM, Al-Sultan NK, Al-Qahtani AA, Ali H, Alkahtani S

OncoTargets and Therapy 2019, 12:21-30

Published Date: 17 December 2018

Case report

Ceritinib for an anaplastic lymphoma kinase rearrangement-positive patient previously treated with alectinib with poor performance status

Kitadai R, Okuma Y, Kawai S

OncoTargets and Therapy 2019, 12:15-19

Published Date: 17 December 2018

Rapid Communication

Pain predicts overall survival in men with metastatic castration-resistant prostate cancer treated with radium-223

Roviello G, Gallicchio R, Bozza G, Rodriquenz MG, Aieta M, Storto G

OncoTargets and Therapy 2019, 12:9-13

Published Date: 17 December 2018

Original Research

Upregulation of circulating miR130a is correlated with development of Barrett’s esophagus and esophageal adenocarcinoma

Wang L, Ji F, Liu G, Wang W, Li Z, Yue Y, Wang Z

OncoTargets and Therapy 2019, 12:1-7

Published Date: 17 December 2018

Rapid Communication

Next-generation sequencing of circulating tumor DNA for detection of gene mutations in lung cancer: implications for precision treatment

Lai J, Du B, Wang Y, Wu R, Yu Z

OncoTargets and Therapy 2018, 11:9111-9116

Published Date: 14 December 2018

Original Research

Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer

Qiu J, Lin X, Zheng T, Tang X, Hua K

OncoTargets and Therapy 2018, 11:9101-9110

Published Date: 14 December 2018

Original Research

miRNA-30c can be used as a target in the diagnosis and treatment of osteosarcoma

Sun R, Muheremu A, Hu Y

OncoTargets and Therapy 2018, 11:9091-9099

Published Date: 14 December 2018

Review

Encorafenib/binimetinib for the treatment of BRAF-mutant advanced, unresectable, or metastatic melanoma: design, development, and potential place in therapy

Sun J, Zager JS, Eroglu Z

OncoTargets and Therapy 2018, 11:9081-9089

Published Date: 14 December 2018

Original Research

Risk factors for lymph node metastasis and the impact of adjuvant chemotherapy on ductal carcinoma in situ with microinvasion: a population-based study

Chen C, Huang S, Huang A, Jia Y, Wang J, Zhang Z, Mao M, Wang L, Zhou J

OncoTargets and Therapy 2018, 11:9071-9080

Published Date: 13 December 2018

Review

The effect of additional chemotherapy on high-risk prostate cancer: a systematic review and meta-analysis

Chen J, Zhang X, Sun G, Zhao J, Liu J, Zhao P, Dai J, Shen P, Zeng H

OncoTargets and Therapy 2018, 11:9061-9070

Published Date: 13 December 2018

Review

Early and late outcomes of bevacizumab plus chemotherapy versus chemotherapy alone as a neoadjuvant treatment in HER2-negative nonmetastatic breast cancer: a meta-analysis of randomized controlled trials

Wei J, Luo Y, Fu D

OncoTargets and Therapy 2018, 11:9049-9059

Published Date: 12 December 2018

Original Research

Curative effectiveness and safety of osimertinib in the treatment for non-small-cell lung cancer: a meta-analysis of the experimental evidence

Chen P, Chen F, Lei J, Zhou B

OncoTargets and Therapy 2018, 11:9033-9047

Published Date: 12 December 2018

Case report

Pseudomyxoma extraperitonei in horseshoe kidney masquerading as renal hilar tumor: a case report

Wang X, Gao X, Wang L, Dai Z, Fan B, Cui H, Liu Z

OncoTargets and Therapy 2018, 11:9027-9032

Published Date: 12 December 2018

Original Research

microRNA-769 is downregulated in colorectal cancer and inhibits cancer progression by directly targeting cyclin-dependent kinase 1

Wang L, Xu M, Lu P, Zhou F

OncoTargets and Therapy 2018, 11:9013-9025

Published Date: 12 December 2018

Case report

A primary retroperitoneal anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with tumor thrombosis

Li J, Tian X, Wang M, Liu W, Guo X, Wang K, Nong L, Wang W, Yang Y

OncoTargets and Therapy 2018, 11:9007-9011

Published Date: 12 December 2018

Original Research

Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl-2 axis

Zhao H, Han L, Jian Y, Ma Y, Yan W, Chen X, Xu H, Li L

OncoTargets and Therapy 2018, 11:8995-9006

Published Date: 11 December 2018

Case report

c.1439delA frameshift deletion mutation in familial adenomatous polyposis

Ma DJ, Wang BS, Yue JB, Li ZJ, Sun YL

OncoTargets and Therapy 2018, 11:8987-8993

Published Date: 11 December 2018

Original Research

Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells

Li X, Zhu G, Yao X, Wang N, Hu R, Kong Q, Zhou D, Long L, Cai J, Zhou W

OncoTargets and Therapy 2018, 11:8977-8985

Published Date: 11 December 2018

Original Research

miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1

Yao R, Zheng H, Wu L, Cai P

OncoTargets and Therapy 2018, 11:8965-8976

Published Date: 11 December 2018

Original Research

MIIP is downregulated in gastric cancer and its forced expression inhibits proliferation and invasion of gastric cancer cells in vitro and in vivo

Sun D, Wang Y, Jiang S, Wang G, Xin Y

OncoTargets and Therapy 2018, 11:8951-8964

Published Date: 11 December 2018

Case report

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

De Carlo E, Schiappacassi M, Urbani M, Doliana R, Baldassarre G, Da Ros V, Santarossa S, Chimienti E, Berto E, Fratino L, Bearz A

OncoTargets and Therapy 2018, 11:8945-8950

Published Date: 10 December 2018

Corrigendum

A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1 [Corrigendum]

Zhao XZ, Wu XH

OncoTargets and Therapy 2018, 11:8943-8944

Published Date: 10 December 2018

Case Series

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms

Ludmir EB, Gutschenritter T, Pinnix CC, Gunther JR, Nastoupil LJ, Khoury JD, Medeiros LJ, Dabaja BS, Milgrom SA

OncoTargets and Therapy 2018, 11:8937-8942

Published Date: 10 December 2018

Review

Osteopontin versus alpha-fetoprotein as a diagnostic marker for hepatocellular carcinoma: a meta-analysis

Sun TT, Tang YR, Sun DW, Bu Q, Li P

OncoTargets and Therapy 2018, 11:8925-8935

Published Date: 10 December 2018

Original Research

The potential functions of FAM46C in oral squamous cell carcinoma

Zhuang X, Lu M

OncoTargets and Therapy 2018, 11:8915-8923

Published Date: 10 December 2018

Case report

Good local tumor control but lethal hemorrhage after apatinib treatment for intractable squamous carcinoma of the floor of the mouth: a case report

Zhu X, Liu M, Lv J, Guo L, Li C, Dong L, Liu B

OncoTargets and Therapy 2018, 11:8909-8913

Published Date: 7 December 2018

Original Research

Drug–target–disease network analysis of gene–phenotype connectivity for genistein in ovarian cancer

Zhang C, Yang F, Ni S, Teng W, Ning Y

OncoTargets and Therapy 2018, 11:8901-8908

Published Date: 10 December 2018

Original Research

Predictive value of positron emission tomography for the prognosis of molecularly targeted therapy in solid tumors

Xie X, Chen H, Yang H, Lin H, Zhou S, Shen R, Lu C, Ling L, Lin W, Liao Z

OncoTargets and Therapy 2018, 11:8885-8899

Published Date: 7 December 2018

Original Research

Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/β-catenin pathway

Tang Z, Cai H, Wang R, Cui Y

OncoTargets and Therapy 2018, 11:8875-8883

Published Date: 7 December 2018

Original Research

miRNA-19 promotes non-small-cell lung cancer cell proliferation via inhibiting CBX7 expression

Peng X, Guan L, Gao B

OncoTargets and Therapy 2018, 11:8865-8874

Published Date: 7 December 2018

Original Research

Overexpressing lncRNA SNHG16 inhibited HCC proliferation and chemoresistance by functionally sponging hsa-miR-93

Xu F, Zha G, Wu Y, Cai W, Ao J

OncoTargets and Therapy 2018, 11:8855-8863

Published Date: 7 December 2018

Original Research

Transcatheter hepatic arterial chemoembolization plus cinobufotalin injection adjuvant therapy for advanced hepatocellular carcinoma: a meta-analysis of 27 trials involving 2,079 patients

Guo N, Miao YY, Sun MZ

OncoTargets and Therapy 2018, 11:8835-8853

Published Date: 7 December 2018

Original Research

Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells

Pérez-Cárdenas E, Taja-Chayeb L, Trejo-Becerril C, Chanona-Vilchis J, Chávez-Blanco A, Domínguez-Gómez G, Langley E, García-Carrancá A, Dueñas-González A

OncoTargets and Therapy 2018, 11:8823-8833

Published Date: 7 December 2018

Original Research

TSPAN7 promotes the migration and proliferation of lung cancer cells via epithelial-to-mesenchymal transition

Wang X, Lin M, Zhao J, Zhu S, Xu M, Zhou X

OncoTargets and Therapy 2018, 11:8815-8822

Published Date: 13 December 2018

Original Research

TRIM37 promotes cell invasion and metastasis by regulating SIP1-mediated epithelial–mesenchymal transition in gastric cancer

Chen D, You X, Pan Y, Liu Q, Cao G

OncoTargets and Therapy 2018, 11:8803-8813

Published Date: 10 December 2018

Original Research

MicroRNA-486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells

Feng L, Jing L, Han J, Wang G, Liu Y, Zhang X, Wang Y, Wang F, Ma H, Liu Y

OncoTargets and Therapy 2018, 11:8791-8801

Published Date: 6 December 2018

Original Research

PIWI-like protein 1 upregulation promotes gastric cancer invasion and metastasis

Gao CL, Sun R, Li DH, Gong F

OncoTargets and Therapy 2018, 11:8783-8789

Published Date: 6 December 2018

Original Research

miR-1 inhibits the proliferation of breast cancer stem cells by targeting EVI-1

Wu L, Wang T, He D, Li X, Jiang Y

OncoTargets and Therapy 2018, 11:8773-8781

Published Date: 6 December 2018

Original Research

SFRP5 inhibits the migration and invasion of melanoma cells through Wnt signaling pathway

Chen Y, Zou D, Wang N, Tan T, Liu Y, Zhao Q, Pu Y, Thapa RJ, Chen J

OncoTargets and Therapy 2018, 11:8761-8772

Published Date: 6 December 2018

Original Research

Inhibition of XIAP increases carboplatin sensitivity in ovarian cancer

Zhang Y, Huang F, Luo Q, Wu X, Liu Z, Chen H, Huang Y

OncoTargets and Therapy 2018, 11:8751-8759

Published Date: 5 December 2018

Original Research

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion

Song S, Li D, Yang C, Yan P, Bai Y, Zhang Y, Hu G, Lin C, Li X

OncoTargets and Therapy 2018, 11:8741-8750

Published Date: 5 December 2018

Original Research

MALAT1 promotes proliferation, migration, and invasion of MG63 cells by upregulation of TGIF2 via negatively regulating miR-129

Liu K, Zhang YG, Liu L, Yuan QL

OncoTargets and Therapy 2018, 11:8729-8740

Published Date: 4 December 2018

Case report

Pathological complete response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with unresectable BRAF V600E-mutant malignant melanoma of the gallbladder

Yu Z, Quiroz E, Shen Y, Jaiyesimi IA

OncoTargets and Therapy 2018, 11:8723-8728

Published Date: 4 December 2018

Original Research

Development and validation of a prognostic signature for preoperative prediction of overall survival in gastric cancer patients

Zhu M, Wang Q, Luo Z, Liu K, Zhang Z

OncoTargets and Therapy 2018, 11:8711-8722

Published Date: 4 December 2018

Case report

Clinical benefit from afatinib in an advanced squamous cell lung carcinoma patient harboring HER2 S310Y mutation: a case report

Gao Y, Zheng AH, Zhu XM, Song J, Xue Q

OncoTargets and Therapy 2018, 11:8705-8710

Published Date: 5 December 2018

Original Research

MiR-411 suppresses the development of bladder cancer by regulating ZnT1

Liu Y, Liu T, Jin H, Yin L, Yu H, Bi J

OncoTargets and Therapy 2018, 11:8695-8704

Published Date: 4 December 2018

Original Research

Application of preoperative three-dimensional model design in radioactive particle implantation for advanced pancreatic cancer

Liu Y, Lyu S, Wang X, Wang Y

OncoTargets and Therapy 2018, 11:8685-8693

Published Date: 4 December 2018

Original Research

Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients

Feldheim J, Kessler AF, Schmitt D, Wilczek L, Linsenmann T, Dahlmann M, Monoranu CM, Ernestus RI, Hagemann C, Löhr M

OncoTargets and Therapy 2018, 11:8673-8684

Published Date: 4 December 2018

Original Research

A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model

Park S, Kim D, Wu G, Jung H, Park JA, Kwon HJ, Lee Y

OncoTargets and Therapy 2018, 11:8655-8672

Published Date: 3 December 2018

Original Research

miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3

Guo J, Liu Q, Li Z, Guo H, Bai C, Wang F

OncoTargets and Therapy 2018, 11:8643-8653

Published Date: 3 December 2018

Original Research

Natural product pectolinarigenin inhibits proliferation, induces apoptosis, and causes G2/M phase arrest of HCC via PI3K/AKT/mTOR/ERK signaling pathway

Wu T, Dong X, Yu D, Shen Z, Yu J, Yan S

OncoTargets and Therapy 2018, 11:8633-8642

Published Date: 3 December 2018

Original Research

Efficacy and safety of PD1/PDL1 blockades versus docetaxel in patients with pretreated advanced non-small-cell lung cancer: a meta-analysis

Liu J, Zhong Y, Peng S, Zhou X, Gan X

OncoTargets and Therapy 2018, 11:8623-8632

Published Date: 3 December 2018

Review

Efficacy and safety of bevacizumab-based combination therapy for treatment of patients with metastatic colorectal cancer

Xu R, Xu C, Liu C, Cui C, Zhu J

OncoTargets and Therapy 2018, 11:8605-8621

Published Date: 4 December 2018

Case report

Intestinal metastasis from breast invasive ductal carcinoma after a long latency: case report and literature review

Liu M, Zhang L, Guo L, Lv J, Shi W, Liu B

OncoTargets and Therapy 2018, 11:8599-8603

Published Date: 3 December 2018

Case report

A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia

Vinhas R, Lourenço A, Santos S, Lemos M, Ribeiro P, Botelho Sousa A, Baptista PV, Fernandes AR

OncoTargets and Therapy 2018, 11:8589-8598

Published Date: 30 November 2018

Original Research

Afatinib versus gemcitabine/cisplatin for first-line treatment of Chinese patients with advanced non-small-cell lung cancer harboring EGFR mutations: subgroup analysis of the LUX-Lung 6 trial

Wu YL, Xu CR, Hu CP, Feng J, Lu S, Huang Y, Li W, Hou M, Shi JH, Märten A, Fan J, Peil B, Zhou C

OncoTargets and Therapy 2018, 11:8575-8587

Published Date: 30 November 2018

Original Research

Afatinib vs erlotinib for second-line treatment of Chinese patients with advanced squamous cell carcinoma of the lung

Lu S, Li W, Zhou C, Hu CP, Qin S, Cheng G, Feng J, Wang J, Cseh A, Peil B, Gibson N, Ehrnrooth E, Zhang L

OncoTargets and Therapy 2018, 11:8565-8573

Published Date: 30 November 2018

Clinical Trial Report

Local analgesic effect of a bioadhesive barrier-forming oral liquid in cancer patients with oral mucositis caused by chemotherapy and/or radiotherapy: a randomized multicenter, single-use, positive-controlled, open-label study

Cheng Y, Qin SK, Chen YP, Dong LH, Sun XD, Yu SY, Wu SK

OncoTargets and Therapy 2018, 11:8555-8564

Published Date: 30 November 2018

Original Research

Vandetanib (ZD6474) induces antiangiogenesis through mTOR–HIF-1 alpha–VEGF signaling axis in breast cancer cells

Li L, Yu J, Jiao S, Wang W, Zhang F, Sun S

OncoTargets and Therapy 2018, 11:8543-8553

Published Date: 29 November 2018

Original Research

A novel long-sustaining system of apatinib for long-term inhibition of the proliferation of hepatocellular carcinoma cells

Wang YL, Tang ZG

OncoTargets and Therapy 2018, 11:8529-8541

Published Date: 29 November 2018

Original Research

Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release

Ma Y, Liu X, Ma Q, Liu Y

OncoTargets and Therapy 2018, 11:8517-8528

Published Date: 29 November 2018

Original Research

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1α

Tang L, Wu J, Cai S, Huang Y, Zhang X, Fu W, Zhuang Q, Li J

OncoTargets and Therapy 2018, 11:8507-8515

Published Date: 29 November 2018

Original Research

Elevated FAM3C promotes cell epithelial–mesenchymal transition and cell migration in gastric cancer

Shi M, Duan G, Nie S, Shen S, Zou X

OncoTargets and Therapy 2018, 11:8491-8505

Published Date: 5 December 2018

Original Research

Upregulation of SOX18 in colorectal cancer cells promotes proliferation and correlates with colorectal cancer risk

Miao Z, Deng X, Shuai P, Zeng J

OncoTargets and Therapy 2018, 11:8481-8490

Published Date: 29 November 2018

Original Research

Overexpression of Mst1 reduces gastric cancer cell viability by repressing the AMPK-Sirt3 pathway and activating mitochondrial fission

Yao S, Yan W

OncoTargets and Therapy 2018, 11:8465-8479

Published Date: 29 November 2018

Original Research

Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells

Yang Y, Zhu F, Wang Q, Ding Y, Ying R, Zeng L

OncoTargets and Therapy 2018, 11:8455-8463

Published Date: 29 November 2018

Rapid Communication

MiR-21-5p promotes the progression of non-small-cell lung cancer by regulating the expression of SMAD7

Li X, Wu X

OncoTargets and Therapy 2018, 11:8445-8454

Published Date: 28 November 2018

Original Research

XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer

Li Q, Ma R, Zhang M

OncoTargets and Therapy 2018, 11:8435-8444

Published Date: 28 November 2018

Original Research

High expression of uPA related to p38MAPK in esophageal cancer indicates poor prognosis

Liu Q, Li W, Yang S, Liu Z

OncoTargets and Therapy 2018, 11:8427-8434

Published Date: 29 November 2018

Original Research

Better efficacy of intrapleural infusion of bevacizumab with pemetrexed for malignant pleural effusion mediated from nonsquamous non-small cell lung cancer

Song X, Chen D, Guo J, Kong L, Wang H, Wang Z

OncoTargets and Therapy 2018, 11:8421-8426

Published Date: 27 November 2018

Original Research

lncRNA FBXL19-AS1 regulates osteosarcoma cell proliferation, migration and invasion by sponging miR-346

Pan RS, He ZX, Ruan WY, Li S, Chen H, Chen ZY, Liu F, Tian XB, Nie YJ

OncoTargets and Therapy 2018, 11:8409-8420

Published Date: 29 November 2018

Original Research

LncRNA ANCR promotes proliferation and radiation resistance of nasopharyngeal carcinoma by inhibiting PTEN expression

Ma X, Zhou J, Liu J, Wu G, Yu Y, Zhu H, Liu J

OncoTargets and Therapy 2018, 11:8399-8408

Published Date: 27 November 2018

Review

A comparison of fulvestrant plus a targeted agent with fulvestrant alone in hormone receptor-positive advanced breast cancer that progressed on prior endocrine therapy: a meta-analysis

Xu L, Yan N, Li Z, Luo L, Wu X, Liu Q, Xu Y, Cao Y

OncoTargets and Therapy 2018, 11:8389-8398

Published Date: 27 November 2018

Original Research

Prognostic roles of mRNA expression of peroxiredoxins in lung cancer

Chen L, Huang C, Yang X, Zhang Q, Chen F

OncoTargets and Therapy 2018, 11:8381-8388

Published Date: 27 November 2018

Original Research

GDF11 restrains tumor growth by promoting apoptosis in pancreatic cancer

Liu Y, Shao L, Chen K, Wang Z, Wang J, Jing W, Hu M

OncoTargets and Therapy 2018, 11:8371-8379

Published Date: 27 November 2018

Original Research

Is APC hypermethylation a diagnostic biomarker for bladder cancer? A meta-analysis

Han W, Wang Y, Fan J, Wang C

OncoTargets and Therapy 2018, 11:8359-8369

Published Date: 27 November 2018

Corrigendum

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells [Corrigendum]

Pan B, Han H, Wu L, Xiong Y, Zhang J, Dong B, Yang Y, Chen J

OncoTargets and Therapy 2018, 11:8357-8358

Published Date: 26 November 2018

Original Research

TGF-beta 1 levels are associated with lymphocyte percentages in patients with lung cancer treated with radiation therapy

Luo J, Hu S, Wei T, Sun J, Liu N, Wang J

OncoTargets and Therapy 2018, 11:8349-8355

Published Date: 26 November 2018

Original Research

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma

Jiang Z, Zhai X, Shi B, Luo D, Jin B

OncoTargets and Therapy 2018, 11:8341-8348

Published Date: 23 November 2018

Review

New developments in the treatment of basal cell carcinoma: update on current and emerging treatment options with a focus on vismodegib

Koelblinger P, Lang R

OncoTargets and Therapy 2018, 11:8327-8340

Published Date: 23 November 2018

Original Research

Prognostic significance of mammary Paget’s disease in Chinese women: a 10 year, population-based, matched cohort study

Zhou H, Lu K, Zheng L, Guo L, Gao Y, Miao X, Chen Z, Wang X

OncoTargets and Therapy 2018, 11:8319-8326

Published Date: 23 November 2018

Original Research

Associations between the NUDT15 R139C polymorphism and susceptibility to thiopurine-induced leukopenia in Asians: a meta-analysis

Liu Y, Meng Y, Wang L, Liu Z, Li J, Dong W

OncoTargets and Therapy 2018, 11:8309-8317

Published Date: 23 November 2018

Original Research

Modified FOLFOX6 as a first-line treatment for patients with advanced gastric cancer with massive ascites or inadequate oral intake

Osumi H, Takahari D, Chin K, Ogura M, Ichimura T, Wakatsuki T, Suzuki T, Ota Y, Nakayama I, Ooki A, Suenaga M, Shinozaki E, Yamaguchi K

OncoTargets and Therapy 2018, 11:8301-8307

Published Date: 23 November 2018

Rapid Communication

Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability

Li M, Yang Y

OncoTargets and Therapy 2018, 11:8293-8299

Published Date: 22 November 2018

Original Research

The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1

Gagat M, Hałas-Wiśniewska M, Zielińska W, Izdebska M, Grzanka D, Grzanka A

OncoTargets and Therapy 2018, 11:8275-8292

Published Date: 22 November 2018

Corrigendum

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage [Corrigendum]

Liu WJ, Yin YB, Sun JY, Feng S, Ma JK, Fu XY, Hou YJ, Yang MF, Sun BL, Fan CD

OncoTargets and Therapy 2018, 11:8273-8274

Published Date: 22 November 2018

Review

The return of gemtuzumab ozogamicin: a humanized anti-CD33 monoclonal antibody–drug conjugate for the treatment of newly diagnosed acute myeloid leukemia

Egan PC, Reagan JL

OncoTargets and Therapy 2018, 11:8265-8272

Published Date: 22 November 2018

Original Research

Platelets enhance the ability of bone-marrow mesenchymal stem cells to promote cancer metastasis

Wang Q, Li Z, Sun L, Chen B, Zhao Y, Shen B, Zhu M, Zhao X, Xu C, Wang M, Xu W, Zhu W

OncoTargets and Therapy 2018, 11:8251-8263

Published Date: 21 November 2018

Review

Clinical efficacy of immune checkpoint inhibitors in the treatment of unresectable advanced or recurrent gastric cancer: an evidence-based review of therapies

Togasaki K, Sukawa Y, Kanai T, Takaishi H

OncoTargets and Therapy 2018, 11:8239-8250

Published Date: 21 November 2018

Original Research

Icotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression

Sun J, Jiang W, Tian D, Guo Q, Shen Z

OncoTargets and Therapy 2018, 11:8227-8237

Published Date: 21 November 2018

Original Research

Cytoskeleton-associated protein 4 is a novel serodiagnostic marker for esophageal squamous-cell carcinoma

Chen L, You C, Jin X, Zhou L, Huang L, Wang Y

OncoTargets and Therapy 2018, 11:8221-8226

Published Date: 20 November 2018

Original Research

Alcoholic liver disease and risk of cholangiocarcinoma: a systematic review and meta-analysis

Xiong J, Yin Z, Xu W, Shen Z, Li Y, Lu X

OncoTargets and Therapy 2018, 11:8211-8219

Published Date: 20 November 2018

Original Research

Afatinib reverses ceritinib resistance (CR) in ALK/ROS1-positive non-small-cell lung cancer cell (NSCLC) via suppression of NRG1 pathway

Chen H, Zhang Q, Zhang Y, Jia B, Zhang B, Wang C

OncoTargets and Therapy 2018, 11:8201-8209

Published Date: 26 November 2018

Case report

Primary clear cell adenocarcinoma of the pancreas: a case report and literature update

Sun PJ, Yu YH, Cui XJ

OncoTargets and Therapy 2018, 11:8197-8200

Published Date: 16 November 2018

Original Research

Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway

Jin YL, Xin LM, Zhou CC, Ren Y

OncoTargets and Therapy 2018, 11:8185-8195

Published Date: 16 November 2018

Original Research

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion

Ye Y, Song Y, Zhuang J, Wang G, Ni J, Zhang S, Xia W

OncoTargets and Therapy 2018, 11:8175-8184

Published Date: 10 December 2018

Original Research

E2F transcription factor 8 promotes cell proliferation via CCND1/p21 in esophageal squamous cell carcinoma

Chang H, Song J, Wu J, Zhang Y

OncoTargets and Therapy 2018, 11:8165-8173

Published Date: 15 November 2018

Original Research

The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells

Jiang H, Fan JJ, Cheng L, Hu P, Liu RB

OncoTargets and Therapy 2018, 11:8153-8163

Published Date: 14 November 2018

Original Research

Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer

Sheng ML, Dong ZH, Xie YP

OncoTargets and Therapy 2018, 11:8143-8151

Published Date: 14 November 2018

Original Research

Potential role of Toll-like receptor 2 expression and polymorphisms in colon cancer susceptibility in the Saudi Arabian population

Semlali A, Parine NR, Al-Numair NS, Almutairi M, Hawsawi YM, Al Amri A, Aljebreen AM, Arafah M, Almadi MA, Azzam NA, Alharbi O, Alanazi MS

OncoTargets and Therapy 2018, 11:8127-8141

Published Date: 14 November 2018

Original Research

In vitro and in vivo superior radiosensitizing effect of berbamine for head and neck squamous cell carcinoma

Zhu H, Ruan S, Jia F, Chu J, Zhu Y, Huang Y, Liu G

OncoTargets and Therapy 2018, 11:8117-8125

Published Date: 14 November 2018

Original Research

Follicle-stimulating hormone inhibits cervical cancer via NF-κB pathway

Shi X, Qiu S, Zhuang W, Wang C, Zhang S, Yuan N, Yuan F, Qiao Y

OncoTargets and Therapy 2018, 11:8107-8115

Published Date: 14 November 2018

Review

Lipocalin 2: a potential therapeutic target for breast cancer metastasis

Hu C, Yang K, Li M, Huang W, Zhang F, Wang H

OncoTargets and Therapy 2018, 11:8099-8106

Published Date: 13 November 2018

Original Research

High expression of TFEB is associated with aggressive clinical features in colorectal cancer

Liang J, Jia X, Wang K, Zhao N

OncoTargets and Therapy 2018, 11:8089-8098

Published Date: 13 November 2018

Original Research

Association of MLH1 single nucleotide polymorphisms with clinical outcomes of first-line irinotecan-based chemotherapy in colorectal cancer

Wang D, Zhang X, Zhang Y, Wu Y, Guan X, Zhu W, Wang M, Qi C, Shen B

OncoTargets and Therapy 2018, 11:8083-8088

Published Date: 13 November 2018

Original Research

Expression of CLIC1 as a potential biomarker for oral squamous cell carcinoma: a preliminary study

Xu Y, Xu J, Feng J, Li J, Jiang C, Li X, Zou S, Wang Q, Li Y

OncoTargets and Therapy 2018, 11:8073-8081

Published Date: 12 November 2018

Original Research

Celecoxib suppresses cutaneous squamous-cell carcinoma cell migration via inhibition of SDF1-induced endocytosis of CXCR4

Gong T, Yu Y, Yang B, Lin M, Huang JW, Cheng B, Ji C

OncoTargets and Therapy 2018, 11:8063-8071

Published Date: 12 November 2018

Review

Clinicopathological and prognostic significance of circulating tumor cells in patients with esophageal cancer: a meta-analysis

Hou J, Zou K, Yang C, Leng X, Xu Y

OncoTargets and Therapy 2018, 11:8053-8061

Published Date: 12 November 2018

Review

Potential clinical application of lncRNAs in non-small cell lung cancer

Lu T, Wang Y, Chen D, Liu J, Jiao W

OncoTargets and Therapy 2018, 11:8045-8052

Published Date: 13 November 2018

Original Research

Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells

Mu M, Li Y, Zhan Y, Li X, Zhang B

OncoTargets and Therapy 2018, 11:8033-8044

Published Date: 13 November 2018

Original Research

miR-517a promotes Warburg effect in HCC by directly targeting FBP1

Zhang D, Li Z, Li T, Luo D, Feng X, Liu Y, Huang J

OncoTargets and Therapy 2018, 11:8025-8032

Published Date: 13 November 2018

Original Research

Patterns of regional nodal relapse after D2 lymphadenectomy in gastric cancer: rethinking the target volume

Yang W, Zhou M, Hu R, Li G, Wang Y, Shen L, Liang L, Yang J, Zhang Z

OncoTargets and Therapy 2018, 11:8015-8024

Published Date: 12 November 2018

Erratum

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6 [Erratum]

Chen C, Zhang Z, Li J, Sun Y

OncoTargets and Therapy 2018, 11:8013-8014

Published Date: 12 November 2018

Original Research

Long noncoding RNA H19 mediated the chemosensitivity of breast cancer cells via Wnt pathway and EMT process

Gao H, Hao G, Sun Y, Li L, Wang Y

OncoTargets and Therapy 2018, 11:8001-8012

Published Date: 9 November 2018

Original Research

Lupeol inhibits growth and migration in two human colorectal cancer cell lines by suppression of Wnt–β-catenin pathway

Wang YH, Hong D, Qian YQ, Tu XZ, Wang KK, Yang XH, Shao SJ, Kong XL, Lou ZF, Jin LJ

OncoTargets and Therapy 2018, 11:7987-7999

Published Date: 9 November 2018

Original Research

The prognostic roles of mRNAs of the exosomes derived from bone marrow stromal cells in common malignancies: a bioinformatic study

Zhao F, Yu YQ

OncoTargets and Therapy 2018, 11:7979-7986

Published Date: 12 November 2018

Original Research

miR-185 suppresses progression of Ewing’s sarcoma via inhibiting the PI3K/AKT and Wnt/β-catenin pathways

Zhang S, Li D, Jiao G, Wang H, Yan T

OncoTargets and Therapy 2018, 11:7967-7977

Published Date: 9 November 2018

Original Research

lncRNA differentiation antagonizing nonprotein coding RNA overexpression accelerates progression and indicates poor prognosis in pancreatic ductal adenocarcinoma

Chen L, Liu J, Tang T, Zhang Y, Liu M, Xu L, Zhang J

OncoTargets and Therapy 2018, 11:7955-7965

Published Date: 9 November 2018

Original Research

Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell carcinoma treated with supracricoid partial laryngectomy or total laryngectomy

Xia X, Zhu YY, Diao WW, Zhu XL, Shi XH, Li WY, Gao ZQ, Li GJ, Chen XM

OncoTargets and Therapy 2018, 11:7947-7953

Published Date: 9 November 2018

Original Research

TRIM37 targets AKT in the growth of lung cancer cells

Dong SM, Pang XQ, Sun HJ, Yuan CL, Mu CY, Zheng S

OncoTargets and Therapy 2018, 11:7935-7945

Published Date: 8 November 2018

Original Research

MicroRNA-18a promotes hepatocellular carcinoma proliferation, migration, and invasion by targeting Bcl2L10

Wang X, Lu J, Cao J, Ma B, Gao C, Qi F

OncoTargets and Therapy 2018, 11:7919-7934

Published Date: 9 November 2018

Original Research

Clinical evaluation of vascular normalization induced by recombinant human endostatin in nasopharyngeal carcinoma via dynamic contrast-enhanced ultrasonography

Yang Z, Kang M, Zhu S, Huang J, Li X, Wang R

OncoTargets and Therapy 2018, 11:7909-7917

Published Date: 8 November 2018

Original Research

Therapeutic strategies of melatonin in cancer patients: a systematic review and meta-analysis

Wang Y, Wang P, Zheng X, Du X

OncoTargets and Therapy 2018, 11:7895-7908

Published Date: 8 November 2018

Original Research

Transcatheter hepatic arterial infusion chemotherapy vs sorafenib in the treatment of patients with hepatocellular carcinoma of Barcelona Clinic Liver Cancer stage C: a meta-analysis of Asian population

Ni JY, Liu SS, Sun HL, Wang WD, Zhong ZL, Hou SN, Chen YT, Xu LF

OncoTargets and Therapy 2018, 11:7883-7894

Published Date: 6 November 2018

Original Research

OCT4, SOX2, and NAN OG positive expression correlates with poor differentiation, advanced disease stages, and worse overall survival in HER2+ breast cancer patients

Yang F, Zhang J, Yang H

OncoTargets and Therapy 2018, 11:7873-7881

Published Date: 6 November 2018

Original Research

Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro

Jiang T, Zhou ML, Fan J

OncoTargets and Therapy 2018, 11:7865-7872

Published Date: 6 November 2018

Original Research

EZH2 contributes to 5-FU resistance in gastric cancer by epigenetically suppressing FBXO32 expression

Wang C, Li X, Zhang J, Ge Z, Chen H, Hu J

OncoTargets and Therapy 2018, 11:7853-7864

Published Date: 5 November 2018

Original Research

TRIM32 overexpression improves chemoresistance through regulation of mitochondrial function in non-small-cell lung cancers

Du Y, Zhang W, Du B, Zang S, Wang X, Mao X, Hu Z

OncoTargets and Therapy 2018, 11:7841-7852

Published Date: 5 November 2018

Original Research

Long noncoding RNA HOXD-AS1 in various cancers: a meta-analysis and TCGA data review

Zhang FH, Chen XW, Xi KH, Qiu ZQ, Wang YH, Gui Y, Hou Y, Chen KB, Zhang XB

OncoTargets and Therapy 2018, 11:7827-7840

Published Date: 5 November 2018

Case report

Intestinal metastasis from primary ROS1-positive lung adenocarcinoma cancer patients responding to crizotinib

Chen HF, Zhang QX, Zhu YC, Du KQ, Li XF, Wu LX, Wang WX, Xu CW

OncoTargets and Therapy 2018, 11:7821-7825

Published Date: 5 November 2018

Original Research

Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer

Wu B, Qi R, Liu X, Qian L, Wu Z

OncoTargets and Therapy 2018, 11:7805-7820

Published Date: 5 November 2018

Original Research

PTPRF as a novel tumor suppressor through deactivation of ERK1/2 signaling in gastric adenocarcinoma

Tian X, Yang C, Yang L, Sun Q, Liu N

OncoTargets and Therapy 2018, 11:7795-7803

Published Date: 2 November 2018

Case report

Huge borderline phyllodes breast tumor with repeated recurrences and progression toward more malignant phenotype: a case report and literature review

Wang Y, Zhang Y, Chen G, Liu F, Liu C, Xu T, Ma Z

OncoTargets and Therapy 2018, 11:7787-7793

Published Date: 2 November 2018

Original Research

Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK

Wang J, Li J, Cao N, Li Z, Han J, Li L

OncoTargets and Therapy 2018, 11:7777-7786

Published Date: 2 November 2018

Original Research

Potential targets of TMEM176A in the growth of glioblastoma cells

Liu Z, An H, Song P, Wang D, Li S, Chen K, Pang Q

OncoTargets and Therapy 2018, 11:7763-7775

Published Date: 2 November 2018

Original Research

Decreased expression of peroxiredoxin1 inhibits proliferation, invasion, and metastasis of ovarian cancer cell

Zheng MJ, Wang J, Wang HM, Gao LL, Li X, Zhang WC, Gou R, Guo Q, Nie X, Liu J, Lin B

OncoTargets and Therapy 2018, 11:7745-7761

Published Date: 2 November 2018

Original Research

MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells

Meng D, Lei M, Han Y, Zhao D, Zhang X, Yang Y, Liu R

OncoTargets and Therapy 2018, 11:7733-7743

Published Date: 2 November 2018

Original Research

Underexpression of INPPL1 is associated with aggressive clinicopathologic characteristics in papillary thyroid carcinoma

Zhou YL, Zheng C, Chen YT, Chen XM

OncoTargets and Therapy 2018, 11:7725-7731

Published Date: 1 November 2018

Original Research

lncRNA PCAT6 promotes non-small cell lung cancer cell proliferation, migration and invasion through regulating miR-330-5p

Cui LH, Xu HR, Yang W, Yu LJ

OncoTargets and Therapy 2018, 11:7715-7724

Published Date: 1 November 2018

Original Research

The clinical feasibility of flexible bronchoscopy interventional therapy in patients with central airway stenosis and respiratory failure caused by malignancy

Wang J, Yang Y, Zha W, Zhang X

OncoTargets and Therapy 2018, 11:7709-7714

Published Date: 1 November 2018

Original Research

Low expression level of ASK1-interacting protein-1 correlated with tumor angiogenesis and poor survival in patients with esophageal squamous cell cancer

Sun D, Chen C, Hu W, Zhong C, Fan L, Song X, Gai Z

OncoTargets and Therapy 2018, 11:7699-7707

Published Date: 1 November 2018

Original Research

A meta-analysis of nivolumab for the treatment of advanced non-small-cell lung cancer

Chen S, Hu B, Li H

OncoTargets and Therapy 2018, 11:7691-7697

Published Date: 31 October 2018

Original Research

16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling

Chen YC, Huang BM, Lee WC, Chen YC

OncoTargets and Therapy 2018, 11:7679-7690

Published Date: 31 October 2018

Original Research

Cytotoxic effect of Drimia maritima bulb extract and induction of mitochondrial apoptotic signaling in human breast cancer cells, MCF-7 and MDA-MB-468

Hamzeloo-Moghadam M, Aghaei M, Abdolmohammadi MH, Khalaj A, Fallahian F

OncoTargets and Therapy 2018, 11:7669-7677

Published Date: 31 October 2018

Review

A systematic review and meta-analysis of gastrointestinal events associated with nonoperative therapies for neuroendocrine tumors

Wu Q, Chen B, Yan G, Yang Z, Xiong L, He J

OncoTargets and Therapy 2018, 11:7655-7668

Published Date: 31 October 2018

Original Research

Acyl-CoA dehydrogenase long chain expression is associated with esophageal squamous cell carcinoma progression and poor prognosis

Yu DL, Li HW, Wang Y, Li CQ, You D, Jiang L, Song YP, Li XH

OncoTargets and Therapy 2018, 11:7643-7653

Published Date: 31 October 2018

Original Research

Clinicopathological analysis of PD-L2 expression in colorectal cancer

Guo PD, Sun ZW, Lai HJ, Yang J, Wu PP, Guo YD, Sun J

OncoTargets and Therapy 2018, 11:7635-7642

Published Date: 1 November 2018

Original Research

Significance of PYK2 level as a prognosis predictor in patients with colon adenocarcinoma after surgical resection

Liu S, Chen L, Xu Y

OncoTargets and Therapy 2018, 11:7625-7634

Published Date: 31 October 2018

Original Research

SIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling

Ouyang L, Yi L, Li J, Yi S, Li S, Liu P, Yang X

OncoTargets and Therapy 2018, 11:7613-7624

Published Date: 1 November 2018

Original Research

Protein tyrosine phosphatase L1 inhibits high-grade serous ovarian carcinoma progression by targeting IκBα

Wang Y, Li M, Huang T, Li J

OncoTargets and Therapy 2018, 11:7603-7612

Published Date: 30 October 2018

Expression of Concern

Knockdown of immature colon carcinoma transcript-I inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest [Expression of concern]

Xie R, Zhang Y, Shen C, Cao X, Gu S, Che X

OncoTargets and Therapy 2018, 11:7601-7602

Published Date: 30 October 2018

Original Research

RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma

Yu Q, Zhang N, Jiang Y, Huang Y, Lian YY, Liu T, Li N, Guan G

OncoTargets and Therapy 2018, 11:7591-7600

Published Date: 2 November 2018

Original Research

GATA3 is downregulated in osteosarcoma and facilitates EMT as well as migration through regulation of slug

Ma L, Xue W, Ma X

OncoTargets and Therapy 2018, 11:7579-7589

Published Date: 30 October 2018

Original Research

ADAMTS8 targets ERK to suppress cell proliferation, invasion, and metastasis of hepatocellular carcinoma

Zhao XT, Yang CR, Wu JH, Nan YM

OncoTargets and Therapy 2018, 11:7569-7578

Published Date: 29 October 2018

Original Research

Sirt3 enhances glioma cell viability by stabilizing Ku70–BAX interaction

Luo K, Huang W, Tang S

OncoTargets and Therapy 2018, 11:7559-7567

Published Date: 29 October 2018

Case report

Successful alternative treatment for relapsed adult acute lymphoblastic leukemia with dendritic cells-cytokine-induced killer cells combined with a rituximab-based regimen

Xiao X, Ye X, Xu C, Huang J

OncoTargets and Therapy 2018, 11:7555-7558

Published Date: 29 October 2018

Original Research

BMP-2 inhibits lung metastasis of osteosarcoma: an early investigation using an orthotopic model

Xiong Q, Wang X, Wang L, Huang Y, Tian X, Fan Y, Lin CY

OncoTargets and Therapy 2018, 11:7543-7553

Published Date: 29 October 2018

Review

Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis

Weng YM, Peng M, Hu MX, Yao Y, Song QB

OncoTargets and Therapy 2018, 11:7529-7542

Published Date: 30 October 2018

Original Research

The impact of immunosenescence on the efficacy of immune checkpoint inhibitors in melanoma patients: a meta-analysis

Li P, Yang X, Feng Y, Wu L, Ma W, Ding G, Wei Y, Sun L

OncoTargets and Therapy 2018, 11:7521-7527

Published Date: 26 October 2018

Original Research

Re-biopsy status among Chinese non-small-cell lung cancer patients who progressed after icotinib therapy

Wang H, Zhang L, Si X, Zhang X, Wang M

OncoTargets and Therapy 2018, 11:7513-7519

Published Date: 26 October 2018

Original Research

miR-23b-3p and miR-130a-5p affect cell growth, migration and invasion by targeting CB1R via the Wnt/β-catenin signaling pathway in gastric carcinoma

Xian X, Tang L, Wu C, Huang L

OncoTargets and Therapy 2018, 11:7503-7512

Published Date: 25 October 2018

Original Research

FAM129B promoted tumor invasion and proliferation via facilitating the phosphorylation of FAK signaling and associated with adverse clinical outcome of non-small cell lung cancer patients

Zhou X, Yang F, Zhang Q, Miao Y, Hu X, Li A, Hou G, Wang Q, Kang J

OncoTargets and Therapy 2018, 11:7493-7501

Published Date: 25 October 2018

Original Research

Long noncoding RNA UCA1 promotes the proliferation, invasion, and migration of nasopharyngeal carcinoma cells via modulation of miR-145

Wu J, Du M, Zhang Q, Zhang W, Fan Y, Yin L, Fei Q, Jiang X, Chen W, Zhu H, Yan P, He X, Bian X

OncoTargets and Therapy 2018, 11:7483-7492

Published Date: 25 October 2018

Original Research

Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis

Li L, Cao Y, Zhou H, Li Y, He B, Zhou X, Nie Z, Liang L, Liu Y, Ye L

OncoTargets and Therapy 2018, 11:7471-7481

Published Date: 26 October 2018

Original Research

The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China

Liu Y, Qian L, Yang J, Huang H, Feng J, Li X, Bian T, Ke H, Liu J, Zhang J

OncoTargets and Therapy 2018, 11:7459-7469

Published Date: 25 October 2018

Original Research

ARHGAP30 suppressed lung cancer cell proliferation, migration, and invasion through inhibition of the Wnt/β-catenin signaling pathway

Mao X, Tong J

OncoTargets and Therapy 2018, 11:7447-7457

Published Date: 24 October 2018

Original Research

Options of medical treatment and laryngeal function preservation in elderly patients with medial wall pyriform sinus cancer

Wang Q, Liu Y, Wu K, Zhao Y, Gao C, Tong B, Zhang M

OncoTargets and Therapy 2018, 11:7441-7446

Published Date: 1 November 2018

Original Research

Regulation of cell proliferation and metastasis by microRNA-593-5p in human gastric cancer

Yu H, Wei W, Cao W, Zhan Z, Yan L, Wu K, Xie D, Cai B, Xie Y, Xiao Q

OncoTargets and Therapy 2018, 11:7429-7440

Published Date: 24 October 2018

Case report

Activated pulmonary tuberculosis in a patient with melanoma during PD-1 inhibition: a case report

He W, Zhang XM, Li WW, Kong C, Wang YY, Zhu LY, Xu RL, Deng GF, Zhang PZ

OncoTargets and Therapy 2018, 11:7423-7427

Published Date: 24 October 2018

Review

Research progress on GP73 in malignant tumors

Liang R, Liu Z, Piao X, Zuo M, Zhang J, Liu Z, Li Y, Lin Y

OncoTargets and Therapy 2018, 11:7417-7421

Published Date: 24 October 2018

Original Research

Comprehensive bioinformatics analysis identifies several potential diagnostic markers and potential roles of cyclin family members in lung adenocarcinoma

Gao LW, Wang GL

OncoTargets and Therapy 2018, 11:7407-7415

Published Date: 24 October 2018

Original Research

Notch1 serves as a prognostic factor and regulates metastasis via regulating EGFR expression in hypopharyngeal squamous cell carcinoma

Tian J, Liu X, Liu X, Jing P, Sa N, Wang H, Xu W

OncoTargets and Therapy 2018, 11:7395-7405

Published Date: 24 October 2018

Original Research

Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma

Cao S, Chen G, Yan L, Li L, Huang X

OncoTargets and Therapy 2018, 11:7385-7394

Published Date: 24 October 2018

Review

The efficacy and safety of immune checkpoint inhibitor combination therapy in lung cancer: a systematic review and meta-analysis

Peng M, Li X, Lei G, Weng YM, Hu MX, Song QB

OncoTargets and Therapy 2018, 11:7369-7383

Published Date: 24 October 2018

Review

Enzalutamide-resistant castration-resistant prostate cancer: challenges and solutions

Tucci M, Zichi C, Buttigliero C, Vignani F, Scagliotti GV, Di Maio M

OncoTargets and Therapy 2018, 11:7353-7368

Published Date: 24 October 2018

Case report

Iodine-125 seed implantation and allogenic natural killer cell immunotherapy for hepatocellular carcinoma after liver transplantation: a case report

Xie S, Wu Z, Zhou L, Liang Y, Wang X, Niu L, Xu K, Chen J, Zhang M

OncoTargets and Therapy 2018, 11:7345-7352

Published Date: 25 October 2018

Original Research

Down-regulation of CXCL 11 inhibits colorectal cancer cell growth and epithelial-mesenchymal transition

Gao YJ, Liu DL, Li S, Yuan GF, Li L, Zhu HY, Cao GY

OncoTargets and Therapy 2018, 11:7333-7343

Published Date: 23 October 2018

Original Research

Clinical characterization of ERBB2 exon 20 insertions and heterogeneity of outcomes responding to afatinib in Chinese lung cancer patients

Liu Z, Wu L, Cao J, Yang Z, Zhou C, Cao L, Wu H, Shen H, Jin M, Zhang Y, Mao X, Xiang J, Ma K, Li B, Zhang T, Hu Y

OncoTargets and Therapy 2018, 11:7323-7331

Published Date: 23 October 2018

Original Research

Radioembolization versus chemoembolization for unresectable hepatocellular carcinoma: a meta-analysis of randomized trials

Casadei Gardini A, Tamburini E, Iñarrairaegui M, Frassineti GL, Sangro B

OncoTargets and Therapy 2018, 11:7315-7321

Published Date: 25 October 2018

Review

MCL-1 inhibition in cancer treatment

Xiang W, Yang CY, Bai L

OncoTargets and Therapy 2018, 11:7301-7314

Published Date: 23 October 2018

Case report

Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer

Salman P, Panay S, Fernández R, Mahave M, Soza-Ried C

OncoTargets and Therapy 2018, 11:7295-7300

Published Date: 23 October 2018

Original Research

Efficacy and safety analysis on dendritic cell-based vaccine-treated high-grade glioma patients: a systematic review and meta-analysis

Li C, Liu T, Zhou B, Zhou Y, Yu H, Sun Y

OncoTargets and Therapy 2018, 11:7277-7293

Published Date: 24 October 2018

Original Research

Radiation therapy’s efficacy on tongue cancer: a population-based survival analysis

Zhu Y, Zhou C, He Q

OncoTargets and Therapy 2018, 11:7271-7276

Published Date: 23 October 2018

Original Research

Thymosin α1 suppresses migration and invasion of PD-L1 high-expressing non-small-cell lung cancer cells via inhibition of STAT3–MMP2 signaling

Bo C, Wu Q, Zhao H, Li X, Zhou Q

OncoTargets and Therapy 2018, 11:7255-7270

Published Date: 23 October 2018

Original Research

Long non-coding RNA ZEB1-AS1 promotes cell invasion and epithelial to mesenchymal transition through inducing ZEB1 expression in cervical cancer

Cheng RJ, Li N, Yang SY, Liu L, Han SY

OncoTargets and Therapy 2018, 11:7245-7253

Published Date: 18 October 2018

Original Research

The elevated glutaminolysis of bladder cancer and T cells in a simulated tumor microenvironment contributes to the up-regulation of PD-L1 expression by interferon-γ

Wang LP, Yang XC, Li D, Liang ZJ, Chen YB, Ma GF, Wang YH, Li YX, Liang Y, Niu HT

OncoTargets and Therapy 2018, 11:7229-7243

Published Date: 18 October 2018

Original Research

TNFα promotes glioblastoma A172 cell mitochondrial apoptosis via augmenting mitochondrial fission and repression of MAPK–ERK–YAP signaling pathways

Lu C, Chen X, Wang Q, Xu X, Xu B

OncoTargets and Therapy 2018, 11:7213-7227

Published Date: 18 October 2018

Original Research

The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes

Devor EJ, Cha E, Warrier A, Miller MD, Gonzalez-Bosquet J, Leslie KK

OncoTargets and Therapy 2018, 11:7205-7211

Published Date: 18 October 2018

Original Research

Knockdown of lncRNA UCA1 inhibits proliferation and invasion of papillary thyroid carcinoma through regulating miR-204/IGFBP5 axis

Liu H, Li R, Guan L, Jiang T

OncoTargets and Therapy 2018, 11:7197-7204

Published Date: 18 October 2018

Original Research

Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma

Su L, Tian J, Sun J, Han N, Feng L, Yu B, Wang Y

OncoTargets and Therapy 2018, 11:7187-7196

Published Date: 18 October 2018

Original Research

Dosimetric comparison of volumetric-modulated arc therapy and intensity-modulated radiation therapy in patients with cervical cancer: a meta-analysis

Bai W, Kou C, Yu W, Li Y, Hua W, Yu L, Wang J

OncoTargets and Therapy 2018, 11:7179-7186

Published Date: 18 October 2018

Original Research

Prognostic value of NEK2 overexpression in digestive system cancers: a meta-analysis and systematic review

Ren Q, Li B, Liu M, Hu Z, Wang Y

OncoTargets and Therapy 2018, 11:7169-7178

Published Date: 18 October 2018

Original Research

Gene expression analyses identify a relationship between stanniocalcin 2 and the malignant behavior of colorectal cancer

Wang J, Sahengbieke S, Xu X, Zhang L, Xu X, Sun L, Deng Q, Wang D, Chen D, Pan Y, Liu Z, Yu S

OncoTargets and Therapy 2018, 11:7155-7168

Published Date: 18 October 2018

Original Research

Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration

Ciccarelli O, Colson A, De Saeger C, Reding R, Sempoux C, Leclercq IA, Stärkel P

OncoTargets and Therapy 2018, 11:7143-7153

Published Date: 17 October 2018

Original Research

Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma

Zhang DY, Liu Z, Lu Z, Sun WL, Ma X, Zhang P, Wu BQ, Cui PY

OncoTargets and Therapy 2018, 11:7133-7142

Published Date: 17 October 2018

Original Research

Overexpression of APC11 predicts worse survival in lung adenocarcinoma

Zhou J, Zhang S, Fu G, He Z, Xu Y, Ye W, Chen Z

OncoTargets and Therapy 2018, 11:7125-7132

Published Date: 17 October 2018

Review

MicroRNA-195: a review of its role in cancers

Yu W, Liang X, Li X, Zhang Y, Sun Z, Liu Y, Wang J

OncoTargets and Therapy 2018, 11:7109-7123

Published Date: 17 October 2018

Review

Mechanisms of resistance to BRAF and MEK inhibitors and clinical update of US Food and Drug Administration-approved targeted therapy in advanced melanoma

Kakadia S, Yarlagadda N, Awad R, Kundranda M, Niu J, Naraev B, Mina L, Dragovich T, Gimbel M, Mahmoud F

OncoTargets and Therapy 2018, 11:7095-7107

Published Date: 17 October 2018

Review

Novel EXO-T vaccine using polyclonal CD4+ T cells armed with HER2-specific exosomes for HER2-positive breast cancer

Li R, Chibbar R, Xiang J

OncoTargets and Therapy 2018, 11:7089-7093

Published Date: 17 October 2018

Original Research

A systematic review and meta-analysis on the effect of angiogenesis blockade for the treatment of gastric cancer

Bai ZG, Zhang ZT

OncoTargets and Therapy 2018, 11:7077-7087

Published Date: 17 October 2018

Original Research

Platelet-to-lymphocyte ratio and lymphocyte-to-white blood cell ratio predict the efficacy of neoadjuvant chemotherapy and the prognosis of locally advanced gastric cancer patients treated with the oxaliplatin and capecitabine regimen

Tang C, Cheng X, Yu S, Wang Y, Hou J, Li Q, Shen Z, Liu T, Cui Y

OncoTargets and Therapy 2018, 11:7061-7075

Published Date: 17 October 2018

Original Research

The functional verification of EGFR-CAR T-cells targeted to hypopharyngeal squamous cell carcinoma

Dong Y, Ding Y, Guo W, Huang J, Yang Z, Zhang Y, Chen X

OncoTargets and Therapy 2018, 11:7053-7059

Published Date: 16 October 2018

Review

Clinical use of FLT3 inhibitors in acute myeloid leukemia

Sutamtewagul G, Vigil CE

OncoTargets and Therapy 2018, 11:7041-7052

Published Date: 16 October 2018

Original Research

Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells

Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T

OncoTargets and Therapy 2018, 11:7031-7040

Published Date: 16 October 2018

Original Research

Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway

Khophai S, Thanee M, Techasen A, Namwat N, Klanrit P, Titapun A, Jarearnrat A, Sa-Ngiamwibool P, Loilome W

OncoTargets and Therapy 2018, 11:7019-7029

Published Date: 16 October 2018

Review

Research progress of the clinicopathologic features of lung adenosquamous carcinoma

Wang J, Wang Y, Tong M, Pan H, Li D

OncoTargets and Therapy 2018, 11:7011-7017

Published Date: 16 October 2018

Review

TIM-3, a promising target for cancer immunotherapy

He Y, Cao J, Zhao C, Li X, Zhou C, Hirsch FR

OncoTargets and Therapy 2018, 11:7005-7009

Published Date: 16 October 2018

Original Research

Decreased pretherapy serum apolipoprotein A-I is associated with extent of metastasis and poor prognosis of non-small-cell lung cancer

Shi H, Huang H, Pu J, Shi DC, Ning Y, Dong Y, Han Y, Zarogoulidis P, Bai C

OncoTargets and Therapy 2018, 11:6995-7003

Published Date: 15 October 2018

Original Research

Inhibition of miR-10a-5p suppresses cholangiocarcinoma cell growth through downregulation of Akt pathway

Gao L, Yang X, Zhang H, Yu M, Long J, Yang T

OncoTargets and Therapy 2018, 11:6981-6994

Published Date: 15 October 2018

Original Research

Genome-scale analysis identifies SERPINE1 and SPARC as diagnostic and prognostic biomarkers in gastric cancer

Liao P, Li W, Liu RZ, Teer JK, Xu BB, Zhang W, Li X, Mcleod HL, He YJ

OncoTargets and Therapy 2018, 11:6969-6980

Published Date: 15 October 2018

Original Research

Identification of critically carcinogenesis-related genes in basal cell carcinoma

Dai J, Lin K, Huang Y, Lu Y, Chen W, Zhang X, He B, Pan Y, Wang S, Fan W

OncoTargets and Therapy 2018, 11:6957-6967

Published Date: 15 October 2018

Original Research

Identification of driver genes associated with chemotherapy resistance of Ewing’s sarcoma

Liao H, Xie X, Xu Y, Huang G

OncoTargets and Therapy 2018, 11:6947-6956

Published Date: 15 October 2018

Original Research

Crizotinib presented with promising efficacy but for concomitant mutation in next-generation sequencing-identified ROS1-rearranged non-small-cell lung cancer

Zeng L, Li Y, Xiao L, Xiong Y, Liu L, Jiang W, Heng J, Qu J, Yang N, Zhang Y

OncoTargets and Therapy 2018, 11:6937-6945

Published Date: 15 October 2018

Original Research

SMAGP a novel biomarker of cervical cancer development and progression

Jia Y, Li H, Liu G, Song F

OncoTargets and Therapy 2018, 11:6925-6935

Published Date: 15 October 2018

Original Research

NFATC2 is a novel therapeutic target for colorectal cancer stem cells

Lang T, Ding X, Kong L, Zhou X, Zhang Z, Ju HX, Ding S

OncoTargets and Therapy 2018, 11:6911-6924

Published Date: 15 October 2018

Review

Targeting VEGF pathway to normalize the vasculature: an emerging insight in cancer therapy

Wu J, Tang Y, Liang X

OncoTargets and Therapy 2018, 11:6901-6909

Published Date: 17 October 2018

Original Research

Synergistic suppression effect on tumor growth of acute myeloid leukemia by combining cytarabine with an engineered oncolytic vaccinia virus

Peng J, Wang S, Fan W, Li S, Wu Y, Mou X, Wang J, Tong X

OncoTargets and Therapy 2018, 11:6887-6900

Published Date: 15 October 2018

Original Research

Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma

Okuno K, Matsubara T, Nakamura T, Iino T, Kakimoto T, Asanuma K, Matsumine A, Sudo A

OncoTargets and Therapy 2018, 11:6879-6886

Published Date: 12 October 2018

Original Research

Downregulation of miR-638 promotes progression of breast cancer and is associated with prognosis of breast cancer patients

Li M, Wang J, Liu H

OncoTargets and Therapy 2018, 11:6871-6877

Published Date: 12 October 2018

Original Research

Low-dose hypomethylating agent decitabine in combination with aclacinomycin and cytarabine achieves a better outcome than standard FLAG chemotherapy in refractory/relapsed acute myeloid leukemia patients with poor-risk cytogenetics and mutations

Li L, Zhang X, Yu H, Zhang M, Xu M, Liu J, Fu Y, Meng H, Lyu C, Li X, Zhou J

OncoTargets and Therapy 2018, 11:6863-6870

Published Date: 12 October 2018

Case report

Malignant mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma harboring an EGFR mutation: a case report

Wang Y, Yang JX, Yu M, Cao DY, Shen K

OncoTargets and Therapy 2018, 11:6853-6862

Published Date: 12 October 2018

Original Research

The lncRNA TUG1 promotes epithelial ovarian cancer cell proliferation and invasion via the WNT/β-catenin pathway

Liu S, Liu Y, Lu Q, Zhou X, Chen L, Liang W

OncoTargets and Therapy 2018, 11:6845-6851

Published Date: 12 October 2018

Case report

Renal Ewing sarcoma/primitive neuroectodermal tumor in a pregnant woman who underwent robot-assisted laparoscopic nephrectomy: a case report and literature review

Miao C, Yang J, Xue J, Zhu J, Chen W, Qin Y, Wang Z

OncoTargets and Therapy 2018, 11:6839-6843

Published Date: 11 October 2018

Original Research

Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells

O'Day EM, Idos GE, Hill C, Chen JW, Wagner G

OncoTargets and Therapy 2018, 11:6827-6838

Published Date: 11 October 2018

Original Research

SATB1 siRNA-encapsulated immunoliposomes conjugated with CD44 antibodies target and eliminate gastric cancer-initiating cells

Yang F, Zheng Z, Zheng L, Qin J, Li H, Xue X, Gao J, Fang G

OncoTargets and Therapy 2018, 11:6811-6825

Published Date: 11 October 2018

Original Research

EGFR-TKI-based vs non-EGFR-TKI-based adjuvant therapy in resected non-small-cell lung cancer with EGFR mutations: a meta-analysis of randomized controlled trials

Wu JX, He Q, Ye F, Zhou QX, Chen HJ, Sun L, Wu H

OncoTargets and Therapy 2018, 11:6803-6810

Published Date: 11 October 2018

Original Research

Upregulation of AKIP1 contributes to metastasis and progression and predicts poor prognosis of patients with colorectal cancer

Jiang W, Yang W, Yuan L, Liu F

OncoTargets and Therapy 2018, 11:6795-6801

Published Date: 11 October 2018

Original Research

Metastatic malignancies and the effect on arterial stiffness and blood pressure levels: the possible role of chemotherapy

Res E, Kyvelou SM, Vlachopoulos C, Manousou K, Tousoulis D, Stefanadis C, Pektasides D

OncoTargets and Therapy 2018, 11:6785-6793

Published Date: 11 October 2018

Original Research

MicroRNA-647 promotes the therapeutic effectiveness of argon–helium cryoablation and inhibits cell proliferation through targeting TRAF2 via the NF-κB signaling pathway in non-small cell lung cancer

Zhang YS, Chen T, Cai Y, Dong J, Bai F, Gao X, Tian L, Duan N, Liu D

OncoTargets and Therapy 2018, 11:6777-6784

Published Date: 10 October 2018

Original Research

Clinical significance of serum total oxidant/antioxidant status in patients with operable and advanced gastric cancer

Du X, Zhang L, Zhang D, Yang L, Fan Y, Dong S

OncoTargets and Therapy 2018, 11:6767-6775

Published Date: 10 October 2018

Original Research

Overexpression of long noncoding RNA NORAD in colorectal cancer associates with tumor progression

Wang L, Du L, Duan W, Yan S, Xie Y, Wang C

OncoTargets and Therapy 2018, 11:6757-6766

Published Date: 10 October 2018

Original Research

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells

Pan B, Han H, Wu L, Xiong Y, Zhang J, Dong B, Yang Y, Chen J

OncoTargets and Therapy 2018, 11:6741-6756

Published Date: 10 October 2018

Original Research

Role of monocyte-to-lymphocyte ratio in predicting sorafenib response in patients with advanced hepatocellular carcinoma

Zhu Z, Xu L, Zhuang L, Ning Z, Zhang C, Yan X, Lin J, Shen Y, Wang P, Meng Z

OncoTargets and Therapy 2018, 11:6731-6740

Published Date: 10 October 2018

Original Research

Circ-DLG 1 promotes the proliferation of esophageal squamous cell carcinoma

Rong J, Wang Q, Zhang Y, Zhu D, Sun H, Tang W, Wang R, Shi W, Cao XF

OncoTargets and Therapy 2018, 11:6723-6730

Published Date: 9 October 2018

Original Research

Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo

Chen M, Lu J, Wei W, Lv Y, Zhang X, Yao Y, Wang L, Ling T, Zou X

OncoTargets and Therapy 2018, 11:6705-6722

Published Date: 10 October 2018

Original Research

Knockdown of RAI14 suppresses the progression of gastric cancer

Chen C, Maimaiti A, Zhang X, Qu H, Sun Q, He Q, Yu W

OncoTargets and Therapy 2018, 11:6693-6703

Published Date: 9 October 2018

Original Research

Effects of thyrotropin suppression on lumber bone mineral density in postmenopausal women with differentiated thyroid carcinoma

Zhang P, Xi H, Yan R

OncoTargets and Therapy 2018, 11:6687-6692

Published Date: 9 October 2018

Original Research

Clinical significance and biological roles of cyclins in gastric cancer

Zhang HP, Li SY, Wang JP, Lin J

OncoTargets and Therapy 2018, 11:6673-6685

Published Date: 9 October 2018

Original Research

Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells

Jiang L, Liang QL, Liang WM, Zhang HJ, Huang J, Yuan GL, Peng XX, Cheng SA, Huang ZG, Zhang XN

OncoTargets and Therapy 2018, 11:6665-6671

Published Date: 9 October 2018

Original Research

YAP regulates ALDH1A1 expression and stem cell property of bladder cancer cells

Zhao AY, Dai YJ, Lian JF, Huang Y, Lin JG, Dai YB, Xu TW

OncoTargets and Therapy 2018, 11:6657-6663

Published Date: 10 October 2018

Original Research

Pim1 promotes cell proliferation and regulates glycolysis via interaction with MYC in ovarian cancer

Wu Y, Deng Y, Zhu J, Duan Y, Weng W, Wu XH

OncoTargets and Therapy 2018, 11:6647-6656

Published Date: 9 October 2018

Original Research

Predictive role of skin rash in advanced pancreatic cancer patients treated with gemcitabine plus erlotinib: a systematic review and meta-analysis

Zeng M, Feng Q, Lu M, Zhou J, Yang Z, Tang J

OncoTargets and Therapy 2018, 11:6633-6646

Published Date: 8 October 2018

Case report

Male accessory breast cancer on the abdominal wall: a case report and literature review

Zhong GB, Ye XQ, Liu JL, Xiao SZ, Huang QH, Wei W

OncoTargets and Therapy 2018, 11:6625-6631

Published Date: 8 October 2018

Original Research

Efficacy and safety of iodine-125 brachytherapy combined with chemotherapy in the treatment of advanced NSCLC in the elderly

Wu C, Li B, Sun G, Peng C, Xiang D

OncoTargets and Therapy 2018, 11:6617-6624

Published Date: 8 October 2018

Original Research

Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro

Liu WJ, Wang H, Peng XW, Wang WD, Liu NW, Wang Y, Lu Y

OncoTargets and Therapy 2018, 11:6605-6615

Published Date: 8 October 2018

Case report

Complete response associated with lenalidomide and celecoxib in a case of primary refractory Hodgkin lymphoma

Garcia-Recio M, Martinez-Serra J, Mestre F, Bento L, Gines J, Ramos R, Daumal J, López P, Sampol A, Gutierrez A

OncoTargets and Therapy 2018, 11:6599-6603

Published Date: 8 October 2018

Original Research

Nodal regulates bladder cancer cell migration and invasion via the ALK/Smad signaling pathway

Li Y, Zhong W, Zhu M, Hu S, Su X

OncoTargets and Therapy 2018, 11:6589-6597

Published Date: 5 October 2018

Original Research

Knockdown of RNF6 inhibits gastric cancer cell growth by suppressing STAT3 signaling

Huang Z, Cai Y, Yang C, Chen Z, Sun H, Xu Y, Chen W, Xu D, Tian W, Wang H

OncoTargets and Therapy 2018, 11:6579-6587

Published Date: 5 October 2018

Original Research

Effects of insulin-like growth factor binding protein 3 on apoptosis of cutaneous squamous cell carcinoma cells

Liu J, Guo Y, Huang Y, Xue H, Bai S, Zhu J, Xia X, Shen B, Fang W

OncoTargets and Therapy 2018, 11:6569-6577

Published Date: 5 October 2018

Original Research

Radiofrequency Ablation of hepatocellular carcinoma: a meta-analysis of overall survival and recurrence-free survival

Casadei Gardini A, Marisi G, Canale M, Foschi FG, Donati G, Ercolani G, Valgiusti M, Passardi A, Frassineti GL, Scarpi E

OncoTargets and Therapy 2018, 11:6555-6567

Published Date: 5 October 2018

Original Research

The efficacy and safety of apatinib for refractory malignancies: a review and meta-analysis

Sun D, Hou H, Zhang C, Zhang X

OncoTargets and Therapy 2018, 11:6539-6554

Published Date: 5 October 2018

Review

Pembrolizumab for the treatment of patients with recurrent locally advanced or metastatic gastric or gastroesophageal junction cancer: an evidence-based review of place in therapy

Mehta R, Shah A, Almhanna K

OncoTargets and Therapy 2018, 11:6525-6537

Published Date: 4 October 2018

Review

Immune-checkpoint inhibitors for combating T-cell dysfunction in cancer

Grywalska E, Pasiarski M, Góźdź S, Roliński J

OncoTargets and Therapy 2018, 11:6505-6524

Published Date: 4 October 2018

Original Research

miR-431-5p alters the epithelial-to-mesenchymal transition markers by targeting UROC28 in hepatoma cells

Kong Q, Han J, Deng H, Wu F, Guo S, Ye Z

OncoTargets and Therapy 2018, 11:6489-6503

Published Date: 4 October 2018

Review

The regulation of cytokine signaling by retinal determination gene network pathway in cancer

Zheng X, Liu Q, Yi M, Qin S, Wu K

OncoTargets and Therapy 2018, 11:6479-6487

Published Date: 4 October 2018

Review

Evolving role of neurokinin 1-receptor antagonists for chemotherapy-induced nausea and vomiting

Navari RM, Schwartzberg LS

OncoTargets and Therapy 2018, 11:6459-6478

Published Date: 4 October 2018

Original Research

TRIM28 is overexpressed in glioma and associated with tumor progression

Su C, Li H, Gao W

OncoTargets and Therapy 2018, 11:6447-6458

Published Date: 10 October 2018

Original Research

Radix Tetrastigma hemsleyani flavone exhibits antitumor activity in colorectal cancer via Wnt/β-catenin signaling pathway

Wu X, Yu N, Zhang Y, Ye Y, Sun W, Ye L, Wu H, Yang Z, Wu L, Wang F

OncoTargets and Therapy 2018, 11:6437-6446

Published Date: 4 October 2018

Original Research

Co-expression network analysis identified CDH11 in association with progression and prognosis in gastric cancer

Chen PF, Wang F, Nie JY, Feng JR, Liu J, Zhou R, Wang HL, Zhao Q

OncoTargets and Therapy 2018, 11:6425-6436

Published Date: 2 October 2018

Review

LncRNA as a diagnostic and prognostic biomarker in bladder cancer: a systematic review and meta-analysis

Quan J, Pan X, Zhao L, Li Z, Dai K, Yan F, Liu S, Ma H, Lai Y

OncoTargets and Therapy 2018, 11:6415-6424

Published Date: 4 October 2018

Original Research

Adverse events risk associated with regorafenib in the treatment of advanced solid tumors: meta-analysis of randomized controlled trials

Yin X, Yin Y, Shen C, Chen H, Wang J, Cai Z, Chen Z, Zhang B

OncoTargets and Therapy 2018, 11:6405-6414

Published Date: 2 October 2018

Original Research

H19 induced by oxidative stress confers temozolomide resistance in human glioma cells via activating NF-κB signaling

Duan S, Li M, Wang Z, Wang L, Liu Y

OncoTargets and Therapy 2018, 11:6395-6404

Published Date: 2 October 2018

Original Research

LINC00460 modulates KDM2A to promote cell proliferation and migration by targeting miR-342-3p in gastric cancer

Wang F, Liang S, Liu X, Han L, Wang J, Du Q

OncoTargets and Therapy 2018, 11:6383-6394

Published Date: 2 October 2018

Case report

Elemene treatment for NSCLC with multiple CNS metastases: a case report and literature review

Han YS, Zhang X, Lu Y, Dong Y, Fu H, Zhang B, Gao Y

OncoTargets and Therapy 2018, 11:6377-6382

Published Date: 2 October 2018

Original Research

NOP7 interacts with β-catenin and activates β-catenin/TCF signaling in hepatocellular carcinoma cells

Wu N, Zhao J, Yuan Y, Lu C, Zhu W, Jiang Q

OncoTargets and Therapy 2018, 11:6369-6376

Published Date: 1 October 2018

Review

Siva-1 emerges as a tissue-specific oncogene beyond its classic role of a proapoptotic gene

Vachtenheim J Jr, Lischke R, Vachtenheim J

OncoTargets and Therapy 2018, 11:6361-6367

Published Date: 1 October 2018

Original Research

Knockdown of CLDN6 inhibits cell proliferation and migration via PI3K/AKT/mTOR signaling pathway in endometrial carcinoma cell line HEC-1-B

Cao X, He GZ

OncoTargets and Therapy 2018, 11:6351-6360

Published Date: 1 October 2018

Original Research

MicroRNA-1225-5p behaves as a tumor suppressor in human glioblastoma via targeting of IRS1

Li D, Chi G, Chen Z, Jin X

OncoTargets and Therapy 2018, 11:6339-6350

Published Date: 28 September 2018

Original Research

Efficacy and safety of weekly nab-paclitaxel plus cisplatin with concurrent intensity-modulated radiotherapy in patients with inoperable, locally advanced esophageal cancer: a pilot trial

Wang D, Zhang W, Qian D, Guan Y, Chen X, Zhang H, Wang J, Pang Q

OncoTargets and Therapy 2018, 11:6333-6338

Published Date: 28 September 2018

Case report

Extramedullary relapse of acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation treated by CAR T-cell therapy: a case report

Wang D, Shi R, Wang Q, Li J

OncoTargets and Therapy 2018, 11:6327-6332

Published Date: 28 September 2018

Original Research

A ten-long non-coding RNA signature for predicting prognosis of patients with cervical cancer

Shen L, Yu H, Liu M, Wei D, Liu W, Li C, Chang Q

OncoTargets and Therapy 2018, 11:6317-6326

Published Date: 28 September 2018

Original Research

miR-218 overexpression suppresses tumorigenesis of papillary thyroid cancer via inactivation of PTEN /PI3K/AKT pathway by targeting Runx2

Han M, Chen L, Wang Y

OncoTargets and Therapy 2018, 11:6305-6316

Published Date: 28 September 2018

Original Research

LINC00152 promotes the growth and invasion of oral squamous cell carcinoma by regulating miR-139-5p

Li M, Ning J, Li Z, Wang J, Zhao C, Wang L

OncoTargets and Therapy 2018, 11:6295-6304

Published Date: 27 September 2018

Original Research

Predictive value of LDH kinetics in bevacizumab treatment and survival of patients with advanced NSCLC

Li B, Li C, Guo M, Shang S, Li X, Xie P, Sun X, Yu J, Wang L

OncoTargets and Therapy 2018, 11:6287-6294

Published Date: 27 September 2018

Original Research

Metabolic syndrome and the incidence of hepatocellular carcinoma: a meta-analysis of cohort studies

Chen Y, Li X, Wu S, Ye W, Lou L

OncoTargets and Therapy 2018, 11:6277-6285

Published Date: 27 September 2018

Case report

POEMS syndrome complicated with multiple ischemic vascular events: case report and review of literature

Găman M, Vlădăreanu AM, Dobrea C, Onisâi M, Marinescu C, Cîşleanu D, Ciufu C, Vasile D, Bumbea H, Voican I

OncoTargets and Therapy 2018, 11:6271-6276

Published Date: 27 September 2018

Original Research

Effect of long non-coding RNA AOC4P on gastrointestinal stromal tumor cells

Hu JC, Wang Q, Jiang LX, Cai L, Zhai HY, Yao ZW, Zhang ML, Feng Y

OncoTargets and Therapy 2018, 11:6259-6269

Published Date: 26 September 2018

Original Research

Overexpression of GPR35 confers drug resistance in NSCLC cells by β-arrestin/Akt signaling

Wang W, Han T, Tong W, Zhao J, Qiu X

OncoTargets and Therapy 2018, 11:6249-6257

Published Date: 26 September 2018

Original Research

PLK1 as a potential prognostic marker of gastric cancer through MEK-ERK pathway on PDTX models

Dang SC, Fan YY, Cui L, Chen JX, Qu JG, Gu M

OncoTargets and Therapy 2018, 11:6239-6247

Published Date: 25 September 2018

Review

Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities

Chaar M, Kamta J, Ait-Oudhia S

OncoTargets and Therapy 2018, 11:6227-6237

Published Date: 25 September 2018

Original Research

MicroRNA-671-3p promotes the proliferation and migration of glioma cells via targeting CKAP4

Lu GF, You CY, Chen YS, Jiang H, Zheng X, Tang W, Wang X, Xu H, Geng F

OncoTargets and Therapy 2018, 11:6217-6226

Published Date: 25 September 2018

Original Research

CAV2 promotes the growth of renal cell carcinoma through the EGFR/PI3K/Akt pathway

Liu F, Shangli Z, Hu Z

OncoTargets and Therapy 2018, 11:6209-6216

Published Date: 25 September 2018

Original Research

SOX2, a stemness gene, induces progression of NSCLC A549 cells toward anchorage-independent growth and chemoresistance to vinblastine

Choe C, Kim H, Min S, Park S, Seo J, Roh S

OncoTargets and Therapy 2018, 11:6197-6207

Published Date: 25 September 2018

Review

Immunotherapy combined with epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer treatment

Liang H, Liu X, Wang M

OncoTargets and Therapy 2018, 11:6189-6196

Published Date: 25 September 2018

Original Research

All-trans retinoic acid-encapsulated, CD20 antibody-conjugated poly(lactic-co-glycolic acid) nanoparticles effectively target and eliminate melanoma-initiating cells in vitro

Chen X, Zhang Z, Yang S, Chen H, Wang D, Li J

OncoTargets and Therapy 2018, 11:6177-6187

Published Date: 25 September 2018

Original Research

Clinical, dosimetric, and position factors for radiation-induced acute esophagitis in intensity-modulated (chemo)radiotherapy for locally advanced non-small-cell lung cancer

Huang J, He TY, Yang RH, Ji TL, Li G

OncoTargets and Therapy 2018, 11:6167-6175

Published Date: 21 September 2018

Original Research

CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial–mesenchymal transition

Cao G, Chen D, Liu G, Pan Y, Liu Q

OncoTargets and Therapy 2018, 11:6153-6165

Published Date: 21 September 2018

Case report

Scalp metastases as first presentation of pulmonary adenocarcinomas: a case report

Yu Q, Subedi S, Tong Y, Wei Q, Xu H, Wang Y, Gong Y, Shi Y

OncoTargets and Therapy 2018, 11:6147-6151

Published Date: 21 September 2018

Original Research

Distribution of CD4+ and CD8+ exhausted tumor-infiltrating lymphocytes in molecular subtypes of Chinese breast cancer patients

Shi F, Chang H, Zhou Q, Zhao YJ, Wu GJ, Song QK

OncoTargets and Therapy 2018, 11:6139-6145

Published Date: 21 September 2018

Original Research

Is long interval from neoadjuvant chemoradiotherapy to surgery optimal for rectal cancer in the era of intensity-modulated radiotherapy?: a prospective observational study

Chang H, Jiang W, Ye WJ, Tao YL, Wang QX, Xiao WW, Gao YH

OncoTargets and Therapy 2018, 11:6129-6138

Published Date: 21 September 2018

Review

Efficacy and safety of apatinib treatment for gastric cancer, hepatocellular carcinoma and non-small cell lung cancer: a meta-analysis

Xue J, Astère M, Zhong M, Lin H, Shen J, Zhu Y

OncoTargets and Therapy 2018, 11:6119-6128

Published Date: 21 September 2018

Original Research

Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy

Li L, Zhang S, Xie D, Chen H, Zheng X, Pan D

OncoTargets and Therapy 2018, 11:6111-6118

Published Date: 20 September 2018

Original Research

Lentivirus-mediated shRNA targeting MUTYH inhibits malignant phenotypes of bladder cancer SW780 cells

Gao Q, Liu Y, Xie H, Zhong Y, Liao X, Zhan H, Zhou Q, Ding M, Yang K, Li A, Liu Y, Mei HB, Cai Z

OncoTargets and Therapy 2018, 11:6101-6109

Published Date: 21 September 2018

Original Research

Efficacy and safety of trastuzumab as maintenance or palliative therapy in advanced HER2-positive gastric cancer

Fu XM, Zhang Y, Yang J, Qi YL, Ming Y, Sun MM, Shang YM, Yang YH, Zhu XY, Gao QL

OncoTargets and Therapy 2018, 11:6091-6100

Published Date: 20 September 2018

Original Research

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6

Chen C, Zhang Z, Li J, Sun Y

OncoTargets and Therapy 2018, 11:6081-6090

Published Date: 20 September 2018

Original Research

LINK-A promotes cell proliferation through the regulation of aerobic glycolysis in non-small-cell lung cancer

Zhao W, Li W, Dai W, Huang N, Qiu J

OncoTargets and Therapy 2018, 11:6071-6080

Published Date: 20 September 2018

Review

Comparison of short-term outcomes between minimally invasive McKeown and Ivor Lewis esophagectomy for esophageal or junctional cancer: a systematic review and meta-analysis

Deng J, Su Q, Ren Z, Wen J, Xue Z, Zhang L, Chu X

OncoTargets and Therapy 2018, 11:6057-6069

Published Date: 20 September 2018

Original Research

Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature

Gallo S, Arcidiacono MV, Tisato V, Piva R, Penolazzi L, Bosi C, Feo CV, Gafà R, Secchiero P

OncoTargets and Therapy 2018, 11:6049-6056

Published Date: 20 September 2018

Original Research

Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo

Wang Y, Meng Y, Zhang S, Wu H, Yang D, Nie C, Hu Q

OncoTargets and Therapy 2018, 11:6039-6048

Published Date: 20 September 2018

Original Research

Oldhamianoside inhibits the growth of ovarian cancer both in vitro and in vivo via adjusting inflammation and angiogenesis signals

Li Z, Zuo Y, Hou L, Dong L, Sun X

OncoTargets and Therapy 2018, 11:6031-6037

Published Date: 19 September 2018

Original Research

The predictive ability of plasma ESR 1 mutations for the efficacy of endocrine therapy in hormone-receptor-positive advanced breast cancer

Du YF, Li N, Jiao X, Li K, Yan SC

OncoTargets and Therapy 2018, 11:6023-6029

Published Date: 19 September 2018

Original Research

Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesis

Zhang X, Feng H, Li Z, Li D, Liu S, Huang H, Li M

OncoTargets and Therapy 2018, 11:6001-6021

Published Date: 19 September 2018

Original Research

Prognostic value of miR-17-5 p in gastrointestinal cancers: a systematic review and meta-analysis

Wang Z, Zhang J, Zhang Z, Jiang Y, Li M, Li Q, Bai L, Yao D, Wang M, Wang X

OncoTargets and Therapy 2018, 11:5991-5999

Published Date: 19 September 2018

Review

PD1/PDL1 inhibitors for the treatment of advanced urothelial bladder cancer

Stenehjem DD, Tran D, Nkrumah MA, Gupta S

OncoTargets and Therapy 2018, 11:5973-5989

Published Date: 19 September 2018

Original Research

TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression

Gao C, Qiao T, Zhang B, Yuan S, Zhuang X, Luo Y

OncoTargets and Therapy 2018, 11:5963-5971

Published Date: 18 September 2018

Case report

Treatment with olaparib monotherapy for BRCA2-mutated refractory intrahepatic cholangiocarcinoma: a case report

Cheng Y, Zhang J, Qin SK, Hua HQ

OncoTargets and Therapy 2018, 11:5957-5962

Published Date: 18 September 2018

Original Research

Identification of the predictive genes for the response of colorectal cancer patients to FOLFOX therapy

Lin HJ, Qiu XK, Zhang B, Zhang JC

OncoTargets and Therapy 2018, 11:5943-5955

Published Date: 17 September 2018

Original Research

Osteopontin promotes cancer cell drug resistance, invasion, and lactate production and is associated with poor outcome of patients with advanced non-small-cell lung cancer

Ouyang XP, Huang Y, Jin X, Zhao W, Hu T, Wu F, Huang J

OncoTargets and Therapy 2018, 11:5933-5941

Published Date: 19 September 2018

Case report

Successful treatment of recurrent rectal implantation metastasis of ovarian cancer by natural orifice specimen extraction surgery: a case report

Su H, Li B, Ren W, Bao M, Wang P, Liu Q, Wang X, Zhou Z, Zhou H

OncoTargets and Therapy 2018, 11:5925-5931

Published Date: 17 September 2018

Original Research

Lipoprotein (a): a promising prognostic biomarker in patients with hepatocellular carcinoma after curative resection

Gao XH, Zhang SS, Chen H, Wang K, Xie W, Wang F

OncoTargets and Therapy 2018, 11:5917-5924

Published Date: 17 September 2018

Review

Therapy-related myeloid neoplasms: clinical perspectives

Fianchi L, Criscuolo M, Fabiani E, Falconi G, Maraglino AME, Voso MT, Pagano L

OncoTargets and Therapy 2018, 11:5909-5915

Published Date: 17 September 2018

Original Research

Laparoscopic procedure compared with open radical hysterectomy with pelvic lymphadenectomy in early cervical cancer: a retrospective study

Guo J, Yang L, Cai J, Xu L, Min J, Shen Y, Xiong Z, Dong W, Bunyamanop V, Wang Z

OncoTargets and Therapy 2018, 11:5903-5908

Published Date: 18 September 2018

Original Research

Elevated urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine and serum uric acid are associated with progression and are prognostic factors of colorectal cancer

Mao L, Guo C, Zheng S

OncoTargets and Therapy 2018, 11:5895-5902

Published Date: 17 September 2018

Original Research

MicroRNA-140-3p enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by targeting pregnenolone X receptor

Li J, Zhao J, Wang H, Li X, Liu A, Qin Q, Li B

OncoTargets and Therapy 2018, 11:5885-5894

Published Date: 17 September 2018

Case report

A case of interstitial lung disease with alveolar hemorrhage induced by pembrolizumab

Sugano T, Seike M, Noro R, Kaburaki S, Tozuka T, Takahashi A, Takano N, Tanaka T, Kashiwada T, Takeuchi S, Minegishi Y, Saito Y, Kubota K, Terasaki Y, Gemma A

OncoTargets and Therapy 2018, 11:5879-5883

Published Date: 17 September 2018

Original Research

Estrogen affects cell growth and IGF-1 receptor expression in renal cell carcinoma

Sun L, Gao Z, Luo L, Tan H, Zhang G

OncoTargets and Therapy 2018, 11:5873-5878

Published Date: 17 September 2018

Original Research

Evaluation of supportive and barrier-protective skin care products in the daily prevention and treatment of cutaneous toxicity during systemic chemotherapy

Lüftner D, Dell’Acqua V, Selle F, Khalil A, Leonardi MC, De La Torre Tomás A, Shenouda G, Romero Fernandez J, Orecchia R, Moyal D, Seité S

OncoTargets and Therapy 2018, 11:5865-5872

Published Date: 17 September 2018

Original Research

DACH 1 inhibits glioma invasion and tumor growth via the Wnt/catenin pathway

Wang J, Zou Y, Wu X, Chen M, Zhang S, Lu X, Wang Q

OncoTargets and Therapy 2018, 11:5853-5863

Published Date: 17 September 2018

Original Research

Long-term response to first-line bevacizumab-based therapy in patients with metastatic breast cancer: results of the observational “LORENA” study

Redondo A, Ramos Vázquez M, Manso L, Gil Gil MJ, Garau Llinas I, García-Garre E, Rodríguez CA, Chacón JI, López-Vivanco G

OncoTargets and Therapy 2018, 11:5845-5852

Published Date: 17 September 2018

Original Research

TMEM119 promotes gastric cancer cell migration and invasion through STAT3 signaling pathway

Zheng P, Wang W, Ji M, Zhu Q, Feng Y, Zhou F, He Q

OncoTargets and Therapy 2018, 11:5835-5844

Published Date: 13 September 2018

Original Research

Combination of carcinoembryonic antigen with the American Joint Committee on Cancer TNM staging system in rectal cancer: a real-world and large population-based study

Liu Q, Lian P, Luo D, Cai S, Li Q, Li X

OncoTargets and Therapy 2018, 11:5827-5834

Published Date: 13 September 2018

Case report

Apatinib combined with docetaxel as a salvage treatment for metastatic esophageal squamous cancer: a case report

Liang LJ, Wen YX, Xia YY, Wang L, Fei JY, Jiang XD

OncoTargets and Therapy 2018, 11:5821-5826

Published Date: 13 September 2018

Original Research

Subgroup analysis reveals molecular heterogeneity and provides potential precise treatment for pancreatic cancers

Zhang H, Zeng J, Tan Y, Lu L, Sun C, Liang Y, Zou H, Yang X, Tan Y

OncoTargets and Therapy 2018, 11:5811-5819

Published Date: 12 September 2018

Original Research

PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation

Lv JM, Chen L, Gao Y, Huang H, Pan XW, Liu X, Chen M, Qu FJ, Li L, Wang JK, Cui XG, Xu DF

OncoTargets and Therapy 2018, 11:5797-5809

Published Date: 12 September 2018

Original Research

Association of GSTP1 and P16 promoter methylation with the risk of HBV-related hepatocellular carcinoma: a meta-analysis

Li Q, Deng CL, Zhang T, Li X

OncoTargets and Therapy 2018, 11:5789-5796

Published Date: 12 September 2018

Original Research

Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips

Tong Q, Wang XL, Li SB, Yang GL, Jin S, Gao ZY, Liu XB

OncoTargets and Therapy 2018, 11:5777-5787

Published Date: 12 September 2018

Review

Ultrasound-mediated microbubble destruction: a new method in cancer immunotherapy

Tu J, Zhang H, Yu J, Liufu C, Chen Z

OncoTargets and Therapy 2018, 11:5763-5775

Published Date: 12 September 2018

Original Research

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

Gomari H, Forouzandeh Moghadam M, Soleimani M

OncoTargets and Therapy 2018, 11:5753-5762

Published Date: 12 September 2018

Original Research

Long noncoding RNA SNHG6 promotes the progression of colorectal cancer through sponging miR-760 and activation of FOXC1

Zhu Y, Xing Y, Chi F, Sun W, Zhang Z, Piao D

OncoTargets and Therapy 2018, 11:5743-5752

Published Date: 12 September 2018

Original Research

SOX5 induces lung adenocarcinoma angiogenesis by inducing the expression of VEGF through STAT3 signaling

Chen X, Zheng Q, Li W, Lu Y, Ni Y, Ma L, Fu Y

OncoTargets and Therapy 2018, 11:5733-5741

Published Date: 11 September 2018

Original Research

IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446

Jin F, Miao Y, Xu P, Qiu X

OncoTargets and Therapy 2018, 11:5723-5731

Published Date: 11 September 2018

Case Series

The incidence and risk factors of hepatotoxicity induced by perioperative hyperthermic intraperitoneal chemotherapy in gastrointestinal carcinoma patients: a retrospective study

Zheng Z, Yu H, Xiong B, Shen S, Yang H, Zhou YF

OncoTargets and Therapy 2018, 11:5715-5722

Published Date: 11 September 2018

Original Research

Helicobacter pylori promotes gastric epithelial cell survival through the PLK1/PI3K/Akt pathway

Xu W, Huang Y, Yang Z, Hu Y, Shu X, Xie C, He C, Zhu Y, Lu N

OncoTargets and Therapy 2018, 11:5703-5713

Published Date: 11 September 2018

Original Research

NEAT1_2—SFPQ axis mediates cisplatin resistance in liver cancer cells in vitro

Ru Y, Chen XJ, Guo WZ, Gao SG, Qi YJ, Chen P, Feng XS, Zhang SJ

OncoTargets and Therapy 2018, 11:5695-5702

Published Date: 11 September 2018

Original Research

Volatile anesthetic sevoflurane suppresses lung cancer cells and miRNA interference in lung cancer cells

Wang L, Wang T, Gu JQ, Su HB

OncoTargets and Therapy 2018, 11:5689-5693

Published Date: 11 September 2018

Original Research

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer

Ying Zhi L, Xu Z, Ning L, Jia Jin L, Hai Cui Y, Hong HG, Fang XJ

OncoTargets and Therapy 2018, 11:5677-5688

Published Date: 10 September 2018

Review

The role of gene sculptor microRNAs in human precancerous lesions

Wang RH, He LY, Zhou SH

OncoTargets and Therapy 2018, 11:5667-5675

Published Date: 10 September 2018

Original Research

MicroRNA-300 suppresses metastasis of oral squamous cell carcinoma by inhibiting epithelial-to-mesenchymal transition

Kang Y, Zhang Y, Sun Y, Wen Y, Sun F

OncoTargets and Therapy 2018, 11:5657-5666

Published Date: 10 September 2018

Original Research

Upregulation of long noncoding RNA CCAT1-L promotes epithelial–mesenchymal transition in gastric adenocarcinoma

Fang H, Liu HM, Wu WH, Liu H, Pan Y, Li WJ

OncoTargets and Therapy 2018, 11:5647-5655

Published Date: 10 September 2018

Original Research

The downregulated long noncoding RNA DHRS4-AS1 is protumoral and associated with the prognosis of clear cell renal cell carcinoma

Wang C, Wang G, Zhang Z, Wang Z, Ren M, Wang X, Li H, Yu Y, Liu J, Cai L, Li Y, Zhang D, Zhang C

OncoTargets and Therapy 2018, 11:5631-5646

Published Date: 10 September 2018

Original Research

Low-frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in PTX-resistant PC-3 cells via the endoplasmic reticulum stress-mediated PI3K/Akt/mTOR signaling pathway

Wu Y, Liu X, Qin Z, Hu L, Wang X

OncoTargets and Therapy 2018, 11:5621-5630

Published Date: 10 September 2018

Original Research

Podoplanin-positive cancer-associated fibroblasts predict poor prognosis in lung cancer patients

Hu G, Zhong K, Chen W, Wang S, Huang L

OncoTargets and Therapy 2018, 11:5607-5619

Published Date: 10 September 2018

Case report

Pembrolizumab and salvage chemotherapy in EGFR T790M-positive non-small-cell lung cancer with high PD-L1 expression

Tozuka T, Seike M, Minegishi Y, Kitagawa S, Kato T, Takano N, Hisakane K, Takahashi S, Kobayashi K, Kashiwada T, Sugano T, Takeuchi S, Kunugi S, Noro R, Saito Y, Kubota K, Gemma A

OncoTargets and Therapy 2018, 11:5601-5605

Published Date: 7 September 2018

Original Research

Preoperative high-sensitivity C-reactive protein to lymphocyte ratio index plays a vital role in the prognosis of hepatocellular carcinoma after surgical resection

Liao M, Chen P, Liao Y, Li J, Yao W, Sun T, Liao W, Su L

OncoTargets and Therapy 2018, 11:5591-5600

Published Date: 7 September 2018

Original Research

RRM1 expression and the clinicopathological characteristics of patients with non-small cell lung cancer treated with gemcitabine

Chen Y, Huang Y, Chen DM, Wu C, Leng QP, Wang WY, Deng MQ, Zhao YX, Yang XH

OncoTargets and Therapy 2018, 11:5579-5589

Published Date: 7 September 2018

Original Research

Hsa_circ_0003998 promotes cell proliferation and invasion by targeting miR-326 in non-small cell lung cancer

Yu W, Jiang H, Zhang H, Li J

OncoTargets and Therapy 2018, 11:5569-5577

Published Date: 7 September 2018

Original Research

CXCR2 is a novel cancer stem-like cell marker for triple-negative breast cancer

Wang Y, Tu L, Du C, Xie X, Liu Y, Wang J, Li Z, Jiang M, Cao D, Yan X, Luo F

OncoTargets and Therapy 2018, 11:5559-5567

Published Date: 6 September 2018

Original Research

Negative correlation of cytoplasm TIMP3 with miR-222 indicates a good prognosis for NSCLC

Lei Y, Liu Z, Yang W

OncoTargets and Therapy 2018, 11:5551-5557

Published Date: 6 September 2018

Case report

Effective treatment of pulmonary adenocarcinoma harboring triple EGFR mutations of L858R, T790M, and cis-C797S by osimertinib, bevacizumab, and brigatinib combination therapy: a case report

Zhao J, Zou M, Lv J, Han Y, Wang G, Wang G

OncoTargets and Therapy 2018, 11:5545-5550

Published Date: 6 September 2018

Original Research

Nomograms for predicting long-term overall survival and disease-specific survival of patients with clear cell renal cell carcinoma

Zhang GH, Wu Y, Zhang JS, Fang ZQ, Liu ZX, Xu ZH, Fan YD

OncoTargets and Therapy 2018, 11:5535-5544

Published Date: 6 September 2018

Original Research

Feasibility of radical hysterectomy in women with FIGO stage IIB cervical cancer: an observation study of 10-year experience in a tertiary center

Yuan L, Guo JQ, Zhang XC, Chen M, Xu CJ, Yao LQ

OncoTargets and Therapy 2018, 11:5527-5533

Published Date: 19 September 2018

Review

Prognostic significance of NANOG expression in solid tumors: a meta-analysis

Zhao LQ, Liu J, Chen S, Fang C, Zhang XQ, Luo ZB

OncoTargets and Therapy 2018, 11:5515-5526

Published Date: 6 September 2018

Corrigendum

An evaluation of the clinical diagnostic value of contrast-enhanced ultrasound combined with contrast-enhanced computed tomography in space-occupying lesions of the kidney [Corrigendum]

Lu J, Jiao D, Cong Z, Tian W

OncoTargets and Therapy 2018, 11:5513-5514

Published Date: 5 September 2018

Original Research

Comparison of efficacy and toxicity between nedaplatin and cisplatin in treating malignant pleural effusion

Zhong LZ, Xu HY, Zhao ZM, Zhang GM, Lin FW

OncoTargets and Therapy 2018, 11:5509-5512

Published Date: 5 September 2018

Original Research

Suppression of c-MET overcomes erlotinib resistance in tongue cancer cells

Huang K, Liu D

OncoTargets and Therapy 2018, 11:5499-5508

Published Date: 5 September 2018

Original Research

Absence of AIF1L contributes to cell migration and a poor prognosis of breast cancer

Liu P, Li W, Hu Y, Jiang Y

OncoTargets and Therapy 2018, 11:5485-5498

Published Date: 5 September 2018

Original Research

Altered fractionation radiotherapy with or without chemotherapy in the treatment of head and neck cancer: a network meta-analysis

Liu Y, Kou C, Bai W, Liu X, Song Y, Zhang L, Wang M, Zhang Y, You Y, Yin Y, Jiang X, Xin Y

OncoTargets and Therapy 2018, 11:5465-5483

Published Date: 4 September 2018

Case Series

Clinical benefit of fulvestrant monotherapy in the multimodal treatment of hormone receptor and HER2 positive advanced breast cancer: a case series

Rusz O, Kószó R, Dobi Á, Csenki M, Valicsek E, Nikolényi A, Uhercsák G, Cserháti A, Kahán Z

OncoTargets and Therapy 2018, 11:5459-5463

Published Date: 4 September 2018

Original Research

Prognostic value of CD44v6 expression in breast cancer: a meta-analysis

Qiao GL, Song LN, Deng ZF, Chen Y, Ma LJ

OncoTargets and Therapy 2018, 11:5451-5457

Published Date: 4 September 2018

Original Research

Mifepristone inhibits proliferation, migration and invasion of HUUA cells and promotes its apoptosis by regulation of FAK and PI3K/AKT signaling pathway

Sang L, Lu D, Zhang J, Du S, Zhao X

OncoTargets and Therapy 2018, 11:5441-5449

Published Date: 4 September 2018

Original Research

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage

Liu WJ, Yin YB, Sun JY, Feng S, Ma JK, Fu XY, Hou YJ, Yang MF, Sun BL, Fan CD

OncoTargets and Therapy 2018, 11:5429-5439

Published Date: 4 September 2018

Original Research

MicroRNA 628 suppresses migration and invasion of breast cancer stem cells through targeting SOS1

Lin C, Gao B, Yan X, Lei Z, Chen K, Li Y, Zeng Q, Chen Z, Li H

OncoTargets and Therapy 2018, 11:5419-5428

Published Date: 4 September 2018

Original Research

Postoperative adjuvant chemo (embolization) therapy for hepatocellular carcinoma with portal vein tumor thrombosis

Zhang YF, Shang H, Zeng XL, Ji H, Li YM, Lu HW

OncoTargets and Therapy 2018, 11:5407-5417

Published Date: 3 September 2018

Original Research

RGD-modified nanoliposomes containing quercetin for lung cancer targeted treatment

Zhou X, Liu H, Zhao H, Wang T

OncoTargets and Therapy 2018, 11:5397-5405

Published Date: 3 September 2018

Case report

Successful cisplatin-etoposide chemotherapy-based treatment of a primary small cell neuroendocrine carcinoma of the tonsil with multiple metastases: a case report

Wang X, Chen Q, Meng J

OncoTargets and Therapy 2018, 11:5391-5395

Published Date: 3 September 2018

Original Research

Expression profiles of long noncoding RNAs in lung adenocarcinoma

Zhao B, Xu H, Ai X, Adalat Y, Tong Y, Zhang J, Yang S

OncoTargets and Therapy 2018, 11:5383-5390

Published Date: 6 September 2018

Original Research

STARD13 is positively correlated with good prognosis and enhances 5-FU sensitivity via suppressing cancer stemness in hepatocellular carcinoma cells

Gao F, Yu XL, Meng RQ, Wang JS, Jia L

OncoTargets and Therapy 2018, 11:5371-5381

Published Date: 31 August 2018

Original Research

SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer

Yi N, Xiao M, Jiang F, Liu Z, Ni W, Lu C, Ni R, Chen W

OncoTargets and Therapy 2018, 11:5359-5370

Published Date: 3 September 2018

Original Research

Genome-wide profiling reveals cancer-related genes with switched alternative polyadenylation sites in colorectal cancer

Yang X, Wu J, Xu W, Tan S, Chen C, Wang X, Sun J, Kang Y

OncoTargets and Therapy 2018, 11:5349-5357

Published Date: 31 August 2018

Case report

Lymphangioleiomyomatosis: a case report and review of diagnosis and treatment

Liu Y, Guo Z, Zhao C, Li X, Liu H, Chen J

OncoTargets and Therapy 2018, 11:5339-5347

Published Date: 31 August 2018

Case Series

Apatinib mesylate tablet in the treatment of advanced malignant melanoma

Yang L, Zhu H, Luo P, Chen S, Xu Y, Wang C

OncoTargets and Therapy 2018, 11:5333-5338

Published Date: 31 August 2018

Original Research

Prognostic role of long non-coding RNA HNF1A-AS1 in Chinese cancer patients: a meta-analysis

Zhuang C, Zheng L, Wang P

OncoTargets and Therapy 2018, 11:5325-5332

Published Date: 31 August 2018

Original Research

Eukaryotic translation initiation factor 3 subunit G (EI F3G) resensitized HC T116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1

Yang C, Liu X, Li C, Li S, Du W, Yang D

OncoTargets and Therapy 2018, 11:5315-5324

Published Date: 31 August 2018

Original Research

E2F3 promotes cancer growth and is overexpressed through copy number variation in human melanoma

Feng Z, Peng C, Li D, Zhang D, Li X, Cui F, Chen Y, He Q

OncoTargets and Therapy 2018, 11:5303-5313

Published Date: 30 August 2018

Original Research

miR-376a inhibits breast cancer cell progression by targeting neuropilin-1 NR

Zhang L, Chen Y, Wang H, Zheng X, Li C, Han Z

OncoTargets and Therapy 2018, 11:5293-5302

Published Date: 30 August 2018

Case report

Successful treatment of relapsed testicular embryonal rhabdomyosarcoma with Endostar and traditional chemotherapy: a case report

Han T, Chen JJ, Luan YT, Chen XX, Yang XD, Zhang Y, Li G, Wang D, Zheng ZD

OncoTargets and Therapy 2018, 11:5287-5291

Published Date: 30 August 2018

Original Research

Microsurgical treatment of parafalcine meningiomas: a retrospective study of 126 cases

Kong X, Gong S, Lee IT, Yang Y

OncoTargets and Therapy 2018, 11:5279-5285

Published Date: 30 August 2018

Original Research

Long noncoding RNA Sox2 overlapping transcript (SOX2OT) promotes non-small-cell lung cancer migration and invasion via sponging microRNA 132 (miR-132)

Zhang K, Li Y, Qu L, Ma X, Zhao H, Tang Y

OncoTargets and Therapy 2018, 11:5269-5278

Published Date: 30 August 2018

Original Research

Prognostic role of aspartate aminotransferase-lymphocyte ratio index in patients with metastatic colorectal cancer: results from the randomized ITACa trial

Casadei Gardini A, Scarpi E, Orlandi E, Tassinari D, Leo S, Bernardini I, Gelsomino F, Tamberi S, Ruscelli S, Vespignani R, Ronconi S, Frassineti GL, Amadori D, Passardi A

OncoTargets and Therapy 2018, 11:5261-5268

Published Date: 29 August 2018

Review

Profile of abemaciclib and its potential in the treatment of breast cancer

Martin JM, Goldstein LJ

OncoTargets and Therapy 2018, 11:5253-5259

Published Date: 29 August 2018

Original Research

miR-361-5p inhibits glioma migration and invasion by targeting SND1

Liu J, Yang J, Yu L, Rao C, Wang Q, Sun CY, Shi CJ, Hua D, Zhou XX, Luo WJ, Wang R, Li WP, Yu SZ

OncoTargets and Therapy 2018, 11:5239-5252

Published Date: 28 August 2018

Original Research

Surgical therapy and next-generation sequencing-based genetic alteration analysis of malignant solitary fibrous tumor of the pleura

Song Z, Yang F, Zhang Y, Fan P, Liu G, Li C, Ding W, Zhang Y, Xu X, Ye Y

OncoTargets and Therapy 2018, 11:5227-5238

Published Date: 28 August 2018

Original Research

Magnolol exerts anticancer activity in hepatocellular carcinoma cells through regulating endoplasmic reticulum stress-mediated apoptotic signaling

Wang YD, Sun XJ, Yang WJ, Li J, Yin JJ

OncoTargets and Therapy 2018, 11:5219-5226

Published Date: 28 August 2018

Original Research

Overexpression of long noncoding RNA LINC00882 is associated with poor prognosis in hepatocellular carcinoma

Zhu L, Huang F, Wan T, Xu H, Zhao Q

OncoTargets and Therapy 2018, 11:5209-5217

Published Date: 13 September 2018

Case report

Radiotherapy for one rectal cancer patient with cirrhosis and moderate to severe thrombocytopenia: a case report

Shi X, Xia H, Zhang W, Li G, Li A

OncoTargets and Therapy 2018, 11:5203-5207

Published Date: 27 August 2018

Original Research

Alternative treatment strategies to sorafenib in patients with advanced hepatocellular carcinoma: a meta-analysis of randomized Phase III trials

Wang H, Wang HF, Yu ZC, Liu HH

OncoTargets and Therapy 2018, 11:5195-5201

Published Date: 27 August 2018

Original Research

125I seed brachytherapy versus external beam radiation therapy for the palliation of painful bone metastases of lung cancer after one cycle of chemotherapy progression

Xiang Z, Wang L, Yan H, Zhong Z, Liu W, Mo Z, Gao F, Zhang F

OncoTargets and Therapy 2018, 11:5183-5193

Published Date: 27 August 2018

Original Research

Prognostic value of SOX2, CyclinD1, P53, and ki-67 in patients with esophageal squamous cell carcinoma

Wang H, Zhou Y, Liu Q, Xu J, Ma Y

OncoTargets and Therapy 2018, 11:5171-5181

Published Date: 24 August 2018

Original Research

Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia

Ding L, Zhang W, Yang L, Pelicano H, Zhou K, Yin R, Huang R, Zeng J

OncoTargets and Therapy 2018, 11:5151-5170

Published Date: 24 August 2018

Original Research

Peripheral blood lymphocyte responses to cytomegalovirus seropositivity after allogeneic-hematopoietic stem cell transplantation

Zhang J, Chen X, Rong G, Xu T, Zhao H, Chen D, Wu L, Huang P, Wang F

OncoTargets and Therapy 2018, 11:5143-5150

Published Date: 24 August 2018

Original Research

Antitumor effects of nadroparin combined with radiotherapy in Lewis lung cancer models

Zhuang X, Qiao T, Yuan S, Zhang Q, Chen W, Luo Y, Xu G

OncoTargets and Therapy 2018, 11:5133-5142

Published Date: 24 August 2018

Original Research

Synergistic antitumoral efficacy of a novel replicative adenovirus SG611-PDCD5 and daunorubicin in human leukemic cells

Zhou YL, Yao QM, Zhou J, Chang Y, Li JL, Wang YZ, Wu HP, Chen YH, Liu YR, Huang XJ, Ruan GR

OncoTargets and Therapy 2018, 11:5121-5132

Published Date: 23 August 2018

Original Research

MiRNA-16 inhibited oral squamous carcinoma tumor growth in vitro and in vivo via suppressing Wnt/β-catenin signaling pathway

Liu L, Jiang H, Zhao J, Wen H

OncoTargets and Therapy 2018, 11:5111-5119

Published Date: 23 August 2018

Original Research

Effect of lncRNA ANRIL silencing on anoikis and cell cycle in human glioma via microRNA-203a

Dai W, Tian C, Jin S

OncoTargets and Therapy 2018, 11:5103-5109

Published Date: 23 August 2018

Review

Spotlight on lorlatinib and its potential in the treatment of NSCLC: the evidence to date

Akamine T, Toyokawa G, Tagawa T, Seto T

OncoTargets and Therapy 2018, 11:5093-5101

Published Date: 22 August 2018

Original Research

Prognostic and clinicopathological significance of DEPTOR expression in cancer patients: a meta-analysis

Hu B, Shi D, Lv X, Wu F, Chen S, Shao Z

OncoTargets and Therapy 2018, 11:5083-5092

Published Date: 22 August 2018

Original Research

miRNA-543 promotes cell migration and invasion by targeting SPOP in gastric cancer

Xu J, Wang F, Wang X, He Z, Zhu X

OncoTargets and Therapy 2018, 11:5075-5082

Published Date: 21 August 2018

Original Research

Risk of bleeding associated with antiangiogenic monoclonal antibodies bevacizumab and ramucirumab: a meta-analysis of 85 randomized controlled trials

Xiao B, Wang W, Zhang D

OncoTargets and Therapy 2018, 11:5059-5074

Published Date: 21 August 2018

Original Research

Analysis of the clinical significance of DCLK1+ colorectal cancer using novel monoclonal antibodies against DCLK1

Dai T, Hu Y, Lv F, Ozawa T, Sun X, Huang J, Han X, Kishi H, Muraguchi A, Jin A

OncoTargets and Therapy 2018, 11:5047-5057

Published Date: 21 August 2018

Retraction

Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling [Retraction]

Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y, Kan Q

OncoTargets and Therapy 2018, 11:5045-5046

Published Date: 21 August 2018

Original Research

Long noncoding RNA XIST promotes proliferation and invasion by targeting miR-141 in papillary thyroid carcinoma

Xu Y, Wang J, Wang J

OncoTargets and Therapy 2018, 11:5035-5043

Published Date: 21 August 2018

Original Research

Minichromosome maintenance protein 2 correlates with the malignant status and regulates proliferation and cell cycle in lung squamous cell carcinoma

Wu W, Wang X, Shan C, Li Y, Li F

OncoTargets and Therapy 2018, 11:5025-5034

Published Date: 20 August 2018

Original Research

Molecular mechanism of activated T cells in breast cancer

Wu J, Li M, Zhang Y, Cai Y, Zhao G

OncoTargets and Therapy 2018, 11:5015-5024

Published Date: 20 August 2018

Case report

Cauda equine syndrome as the primary symptom of leptomeningeal metastases from lung cancer: a case report and review of literature

Liu Y, Wang B, Qian Y, Di D, Wang M, Zhang X

OncoTargets and Therapy 2018, 11:5009-5013

Published Date: 20 August 2018

Original Research

Long non-coding RNA MEG3 suppresses survival, migration, and invasion of cervical cancer

Chen X, Qu J

OncoTargets and Therapy 2018, 11:4999-5007

Published Date: 20 August 2018

Case Series

ALK-rearrangement neuroendocrine carcinoma of the lung: a comprehensive study of a rare case series and review of literature

Zheng Q, Zheng M, Jin Y, Shen X, Shan L, Shen L, Sun Y, Chen H, Li Y

OncoTargets and Therapy 2018, 11:4991-4998

Published Date: 17 August 2018

Original Research

High CEP55 expression is associated with poor prognosis in non-small-cell lung cancer

Jiang C, Zhang Y, Li Y, Lu J, Huang Q, Xu R, Feng Y, Yan S

OncoTargets and Therapy 2018, 11:4979-4990

Published Date: 17 August 2018

Original Research

Long non-coding RNA NAP1L6 promotes tumor progression and predicts poor prognosis in prostate cancer by targeting Inhibin-β A

Zheng Y, Gao Y, Li X, Si S, Xu H, Qi F, Wang J, Cheng G, Hua L, Yang H

OncoTargets and Therapy 2018, 11:4965-4977

Published Date: 17 August 2018

Original Research

Reduced expression of Nrdp1 predicts a poor prognosis in human hepatocellular carcinoma

Shao X, Lu Q, Wang G, Huang W, Yang L, Chen Z

OncoTargets and Therapy 2018, 11:4955-4963

Published Date: 17 August 2018

Original Research

Injection of an SV40 transcriptional terminator causes embryonic lethality: a possible zebrafish model for screening nonhomologous end-joining inhibitors

Yang Z, Chen S, Xue S, Li X, Hu J, Sun Z, Cui H

OncoTargets and Therapy 2018, 11:4945-4953

Published Date: 17 August 2018

Original Research

The effects of beta-blocker use on cancer prognosis: a meta-analysis based on 319,006 patients

Na Z, Qiao X, Hao X, Fan L, Xiao Y, Shao Y, Sun M, Feng Z, Guo W, Li J, Li J, Li D

OncoTargets and Therapy 2018, 11:4913-4944

Published Date: 20 August 2018

Original Research

MicroRNA-21-5p promotes proliferation of gastric cancer cells through targeting SMAD7

Jiang Y, Zhang M, Guo T, Yang C, Zhang C, Hao J

OncoTargets and Therapy 2018, 11:4901-4911

Published Date: 15 August 2018

Original Research

Downregulation of lncRNA ANRIL suppresses growth and metastasis in human osteosarcoma cells

Guan H, Mei Y, Mi Y, Li C, Sun X, Zhao X, Liu J, Cao W, Li Y, Wang Y

OncoTargets and Therapy 2018, 11:4893-4899

Published Date: 14 August 2018

Original Research

Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis

Gao S, Zhao ZY, Wu R, Zhang Y, Zhang ZY

OncoTargets and Therapy 2018, 11:4877-4891

Published Date: 14 August 2018

Original Research

PRMT7 contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with HSPA5 and EEF2

Cheng D, He Z, Zheng L, Xie D, Dong S, Zhang P

OncoTargets and Therapy 2018, 11:4869-4876

Published Date: 14 August 2018

Original Research

Prognostic value of nutritional markers in nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy: a propensity score matching study

Oei RW, Ye L, Huang J, Kong F, Xu T, Shen C, Wang X, He X, Kong L, Hu C, Ying H

OncoTargets and Therapy 2018, 11:4857-4868

Published Date: 14 August 2018

Original Research

Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics

Ge H, Yan Y, Wu D, Huang Y, Tian F

OncoTargets and Therapy 2018, 11:4845-4855

Published Date: 14 August 2018

Original Research

MicroRNA-194 regulates cell viability and apoptosis by targeting CDH2 in prostatic cancer

Gao S, Zhao Z, Wu R, Wu L, Tian X, Zhang Z

OncoTargets and Therapy 2018, 11:4837-4844

Published Date: 14 August 2018

Review

Adenosquamous carcinoma of the lung

Li C, Lu H

OncoTargets and Therapy 2018, 11:4829-4835

Published Date: 14 August 2018

Review

Spotlight on copanlisib and its potential in the treatment of relapsed/refractory follicular lymphoma: evidence to date

Mensah FA, Blaize JP, Bryan LJ

OncoTargets and Therapy 2018, 11:4817-4827

Published Date: 13 August 2018

Case Series

Mesenteric fibromatosis misdiagnosed with lymph node metastasis after successful laparoscopic right hemicolectomy: a report of two cases with review of literature

Wang P, Zhou H, Zhou Z, Liang J

OncoTargets and Therapy 2018, 11:4811-4816

Published Date: 13 August 2018

Review

Intestinal microbiota: a novel perspective in colorectal cancer biotherapeutics

Ding C, Tang W, Fan X, Wu G

OncoTargets and Therapy 2018, 11:4797-4810

Published Date: 13 August 2018

Original Research

Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro

Tian Y, Liu Z, Zhang L, Zhang J, Han X, Wang Q, Cheng W

OncoTargets and Therapy 2018, 11:4785-4795

Published Date: 10 August 2018

Original Research

sLAG-3 in non-small-cell lung cancer patients’ serum

He Y, Wang Y, Zhao S, Zhao C, Zhou C, Hirsch FR

OncoTargets and Therapy 2018, 11:4781-4784

Published Date: 13 August 2018

Original Research

MSX1 induces G0/G1 arrest and apoptosis by suppressing Notch signaling and is frequently methylated in cervical cancer

Yue Y, Zhou K, Li J, Jiang S, Li C, Men H

OncoTargets and Therapy 2018, 11:4769-4780

Published Date: 10 August 2018

Original Research

An integrated bioinformatical analysis to evaluate the role of KIF4A as a prognostic biomarker for breast cancer

Xue D, Cheng P, Han M, Liu X, Xue L, Ye C, Wang K, Huang J

OncoTargets and Therapy 2018, 11:4755-4768

Published Date: 10 August 2018

Original Research

Effect of KI-67 positive cellular index on prognosis after hepatectomy in Barcelona Clinic Liver Cancer stage A and B hepatocellular carcinoma with microvascular invasion

Li HH, Qi LN, Ma L, Chen ZS, Xiang BD, Li LQ

OncoTargets and Therapy 2018, 11:4747-4754

Published Date: 10 August 2018

Case report

The effectiveness of afatinib and osimertinib in a Chinese patient with advanced lung adenocarcinoma harboring a rare triple EGFR mutation (R670W/H835L/L833V): a case report and literature review

Qin BD, Jiao XD, Yuan LY, Liu K, Wang Z, Qin WX, Zang YS

OncoTargets and Therapy 2018, 11:4739-4745

Published Date: 10 August 2018

Case report

Non-small cell lung cancer leptomeningeal metastases treated with intrathecal therapy plus osimertinib and temozolomide and whole-brain radiation therapy: a case report

Wang Y, Liu S, Wei X, Yan B, Li J, Su Z, Liu A, Zhang Y

OncoTargets and Therapy 2018, 11:4733-4738

Published Date: 10 August 2018

Original Research

Enhanced anticancer effects of low-dose curcumin with non-invasive pulsed electric field on PANC-1 cells

Lu CH, Lin SH, Hsieh CH, Chen WT, Chao CY

OncoTargets and Therapy 2018, 11:4723-4732

Published Date: 10 August 2018

Original Research

miR-497 inhibited proliferation, migration and invasion of thyroid papillary carcinoma cells by negatively regulating YAP1 expression

Cheng H, Dong H, Feng J, Tian H, Zhang H, Xu L

OncoTargets and Therapy 2018, 11:4711-4721

Published Date: 10 August 2018

Original Research

Characterization of microRNA expression in primary human colon adenocarcinoma cells (SW480) and their lymph node metastatic derivatives (SW620)

Yan W, Yang W, Liu Z, Wu G

OncoTargets and Therapy 2018, 11:4701-4709

Published Date: 10 August 2018

Original Research

B7-H3 promotes metastasis, proliferation, and epithelial-mesenchymal transition in lung adenocarcinoma

Yu TT, Zhang T, Lu X, Wang RZ

OncoTargets and Therapy 2018, 11:4693-4700

Published Date: 10 August 2018

Review

Stereotactic body radiotherapy using the CyberKnife® system in the treatment of patients with liver metastases: state of the art

Ihnát P, Skácelíková E, Tesař M, Penka I

OncoTargets and Therapy 2018, 11:4685-4691

Published Date: 10 August 2018

Review

Drug response to PD-1/PD-L1 blockade: based on biomarkers

Chen Q, Li T, Yue W

OncoTargets and Therapy 2018, 11:4673-4683

Published Date: 8 August 2018

Original Research

Eyes absent homologue 2 predicts a favorable prognosis in colorectal cancer

Zheng J, Cao F, Huang X, Ramen K, Xu X, Zhu Y, Chang W, Shan Y, Guo A

OncoTargets and Therapy 2018, 11:4661-4671

Published Date: 8 August 2018

Original Research

Relationship of PPARG, PPARGC1A, and PPARGC1B polymorphisms with susceptibility to hepatocellular carcinoma in an eastern Chinese Han population

Zhang S, Jiang J, Chen Z, Wang Y, Tang W, Chen Y, Liu L

OncoTargets and Therapy 2018, 11:4651-4660

Published Date: 8 August 2018

Original Research

The efficacy and safety of intravesical gemcitabine vs Bacille Calmette-Guérin for adjuvant treatment of non-muscle invasive bladder cancer: a meta-analysis

Ye Z, Chen J, Hong Y, Xin W, Yang S, Rao Y

OncoTargets and Therapy 2018, 11:4641-4649

Published Date: 8 August 2018

Original Research

A long noncoding RNA MAP3K1-2 promotes proliferation and invasion in gastric cancer

Wu L, Yin JH, Guan YY, Liu HL, Shen HL, Wang XJ, Han BH, Zhou MW, Gu XD

OncoTargets and Therapy 2018, 11:4631-4639

Published Date: 7 August 2018

Case report

Effective nivolumab sequential thoracic radiotherapy in elderly patients with advanced squamous cell lung cancer: did radiation therapy play a role? A case report

Lazzari G, Terlizzi A, Porrazzo G, Devicienti S, Perri F, Della Vittoria Scarpati G, Silvano G

OncoTargets and Therapy 2018, 11:4621-4629

Published Date: 7 August 2018

Original Research

CTLA4 tagging polymorphisms and risk of colorectal cancer: a case–control study involving 2,306 subjects

Zou C, Qiu H, Tang W, Wang Y, Lan B, Chen Y

OncoTargets and Therapy 2018, 11:4609-4619

Published Date: 7 August 2018

Review

Current status and dilemma of second-line treatment in advanced pancreatic cancer: is there a silver lining?

Hua J, Shi S, Liang D, Liang C, Meng Q, Zhang B, Ni Q, Xu J, Yu X

OncoTargets and Therapy 2018, 11:4591-4608

Published Date: 6 August 2018

Review

Brentuximab vedotin in Hodgkin lymphoma and anaplastic large-cell lymphoma: an evidence-based review

Donato EM, Fernández-Zarzoso M, Hueso JA, de la Rubia J

OncoTargets and Therapy 2018, 11:4583-4590

Published Date: 6 August 2018

Original Research

Change in non-small-cell lung cancer tumor size in patients treated with nintedanib plus docetaxel: analyses from the Phase III LUME-Lung 1 study

Reck M, Mellemgaard A, Novello S, Postmus PE, Gaschler-Markefski B, Kaiser R, Buchner H

OncoTargets and Therapy 2018, 11:4573-4582

Published Date: 6 August 2018

Original Research

Phytochemical analysis and antioxidant and anticancer activities of mastic gum resin from Pistacia atlantica subspecies kurdica

Rahman HS

OncoTargets and Therapy 2018, 11:4559-4572

Published Date: 6 August 2018

Original Research

Prognostic value of selected preoperative inflammation-based scores in patients with high-risk localized prostate cancer who underwent radical prostatectomy

Shu K, Zheng Y, Chen J, Li W, Jiang K

OncoTargets and Therapy 2018, 11:4551-4558

Published Date: 3 August 2018

Case report

Case report of a primary prostatic urothelial carcinoma patient with sustained fever

Zhang S, Guo Z

OncoTargets and Therapy 2018, 11:4547-4550

Published Date: 3 August 2018

Original Research

Hypoxia-regulated lncRNA CRPAT4 promotes cell migration via regulating AVL9 in clear cell renal cell carcinomas

Zhang W, Wang J, Chai R, Zhong G, Zhang C, Cao W, Yan L, Zhang X, Xu Z

OncoTargets and Therapy 2018, 11:4537-4545

Published Date: 3 August 2018

Original Research

Relationship between HER2 gene status and selected potential biological features related to trastuzumab resistance and its influence on survival of breast cancer patients undergoing trastuzumab adjuvant treatment

Adamczyk A, Kruczak A, Harazin-Lechowska A, Ambicka A, Grela-Wojewoda A, Domagała-Haduch M, Janecka-Widła A, Majchrzyk K, Cichocka A, Ryś J, Niemiec J

OncoTargets and Therapy 2018, 11:4525-4535

Published Date: 3 August 2018

Original Research

Melittin induces NSCLC apoptosis via inhibition of miR-183

Gao D, Zhang J, Bai L, Li F, Dong Y, Li Q

OncoTargets and Therapy 2018, 11:4511-4523

Published Date: 1 August 2018

Original Research

HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma

Wu CZ, Zheng JJ, Bai YH, Xia P, Zhang HC, Guo Y

OncoTargets and Therapy 2018, 11:4501-4510

Published Date: 1 August 2018

Original Research

Cancer/testis antigens (CTAs) expression in resected lung cancer

Jin S, Cao S, Li J, Meng Q, Wang C, Yao L, Lang Y, Cao J, Shen J, Pan B, Hu J, Yu Y

OncoTargets and Therapy 2018, 11:4491-4499

Published Date: 1 August 2018

Original Research

Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo

Zhang Y, Zhang XX, Yuan RY, Ren T, Shao ZY, Wang HF, Cai WL, Chen LT, Wang XA, Wang P

OncoTargets and Therapy 2018, 11:4479-4490

Published Date: 1 August 2018

Original Research

miR-141-3p is a key negative regulator of the EGFR pathway in osteosarcoma

Wang J, Wang G, Li B, Qiu C, He M

OncoTargets and Therapy 2018, 11:4461-4478

Published Date: 31 July 2018

Original Research

Metformin induces miR-378 to downregulate the CDK1, leading to suppression of cell proliferation in hepatocellular carcinoma

Zhou J, Han S, Qian W, Gu Y, Li X, Yang K

OncoTargets and Therapy 2018, 11:4451-4459

Published Date: 31 July 2018

Corrigendum

Effect of first-line endocrine therapy in patients with hormone-sensitive advanced breast cancer: a network meta-analysis [Corrigendum]

Zhang T, Feng F, Zhao W, Tian J, Yao Y, Zhou C, Dong S, Wang C, Zang C, Lv Q, Sun C

OncoTargets and Therapy 2018, 11:4449-4450

Published Date: 31 July 2018

Original Research

Outcome of eribulin as a late treatment line for Thai metastatic breast cancer patients

Ditsatham C, Chitapanarux I, Somwangprasert A, Watcharachan K, Wongmaneerung P, Charoentum C, Chewaskulyong B, Chakrabandhu S, Onchan W, Teeyasuntranonn A, Sripan P

OncoTargets and Therapy 2018, 11:4443-4447

Published Date: 31 July 2018

Original Research

LINC00888 promoted tumorigenicity of melanoma via miR-126/CRK signaling axis

Lu W, Tao X, Fan Y, Tang Y, Xu X, Fan S, Huang Y, Yu Y, Luo D

OncoTargets and Therapy 2018, 11:4431-4442

Published Date: 31 July 2018

Original Research

Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NFκB signaling pathway

Xue Y, Yang L, Li J, Yan Y, Jiang Q, Shen L, Yang S, Shen B, Huang R, Yan J, Guo H

OncoTargets and Therapy 2018, 11:4413-4429

Published Date: 30 July 2018

Case report

Reversible posterior leukoencephalopathy syndrome induced by apatinib: a case report and literature review

Li XT, Chai J, Wang Z, Lu L, Zhao QY, Zhou J, Ju F

OncoTargets and Therapy 2018, 11:4407-4411

Published Date: 30 July 2018

Original Research

Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest

Li XQ, Bai YL, Zhang DL, Jiao HS, He RX

OncoTargets and Therapy 2018, 11:4395-4405

Published Date: 27 July 2018

Review

HOXA11-AS: a novel regulator in human cancer proliferation and metastasis

Xue JY, Huang C, Wang W, Li HB, Sun Ming, Xie M

OncoTargets and Therapy 2018, 11:4387-4393

Published Date: 27 July 2018

Original Research

Extracts and components of Ficus carica leaves suppress survival, cell cycle, and migration of triple-negative breast cancer MDA-MB-231 cells

Zhang Y, Wan Y, Huo B, Li B, Jin Y, Hu X

OncoTargets and Therapy 2018, 11:4377-4386

Published Date: 27 July 2018

Study Protocol

Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer

Ding MN, Li Y, Yang Y, Zhu K, Che SL, Lin ZH, Chen LY

OncoTargets and Therapy 2018, 11:4367-4375

Published Date: 26 July 2018

Original Research

The role of lncRNA CASC2 on prognosis of malignant tumors: a meta-analysis and bioinformatics

Yu L, Chen S, Bao H, Zhang W, Liao M, Liang Q, Cheng X

OncoTargets and Therapy 2018, 11:4355-4365

Published Date: 25 July 2018

Original Research

18F-fluorodeoxyglucose positron emission tomography predicts lymph node responses to definitive chemoradiotherapy in esophageal squamous cell carcinoma patients

Zhu W, Zhang Y, Kong L, Huang Y, Zheng J, Wang R, Li M, Yu J

OncoTargets and Therapy 2018, 11:4345-4353

Published Date: 25 July 2018

Original Research

Polymorphism of IFN-γ+874T/A associated with production of IFN-γ affects human papillomavirus susceptibility in rural women from Luohe, Henan, China

Zhang QW, Song JY, Yu JH, Sun MZ, Tang SY, Yang SZ, Cao LJ, Wang HF, Cui LN, Fu XH

OncoTargets and Therapy 2018, 11:4339-4344

Published Date: 25 July 2018

Original Research

Identification of prognostic risk factors for esophageal adenocarcinoma using bioinformatics analysis

Dong Z, Wang J, Zhan T, Xu S

OncoTargets and Therapy 2018, 11:4327-4337

Published Date: 25 July 2018

Original Research

Endoplasmic reticulum stress-mediated autophagy contributes to 5-ethylamino-9-diethylaminobenzo[a]phenoselenazinium-mediated photodynamic therapy via the PERK–eIF2α pathway

Chen J, Huang JH, Wang Z, Song X, Chen Z, Zeng Q, Zhou X, Zuo Z, Zhao S, Chen X, Kang J

OncoTargets and Therapy 2018, 11:4315-4325

Published Date: 24 July 2018

Original Research

Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-κB, uPA activator, and MMP-9

Rajasinghe LD, Pindiprolu RH, Gupta SV

OncoTargets and Therapy 2018, 11:4301-4314

Published Date: 24 July 2018

Original Research

Analysis of change in microRNA expression profiles of lung cancer A549 cells treated with Radix tetrastigma hemsleyani flavonoids

Liu P, Yang X, Zhang H, Pu J, Wei K

OncoTargets and Therapy 2018, 11:4283-4300

Published Date: 24 July 2018

Original Research

Efficacy of bevacizumab versus epidermal growth factor receptor inhibitors for wild-type RAS metastatic colorectal cancer: a meta-analysis

Jiang W, Yu Q, Ning R, Zhao W, Wei C

OncoTargets and Therapy 2018, 11:4271-4281

Published Date: 24 July 2018

Review

Effects of miRNAs on functions of breast cancer stem cells and treatment of breast cancer

Zhang Y, Xu B, Zhang XP

OncoTargets and Therapy 2018, 11:4263-4270

Published Date: 24 July 2018

Original Research

Transcobalamin I: a novel prognostic biomarker of neoadjuvant chemotherapy in locally advanced hypopharyngeal squamous cell cancers

Wang Y, Yue C, Fang J, Gong L, Lian M, Wang R, Feng L, Ma H, Ma Z, Liu H

OncoTargets and Therapy 2018, 11:4253-4261

Published Date: 24 July 2018

Original Research

Comparable efficacy and less toxicity of pegylated liposomal doxorubicin versus epirubicin for neoadjuvant chemotherapy of breast cancer: a case-control study

Dong M, Luo L, Ying X, Lu X, Shen J, Jiang Z, Wang L

OncoTargets and Therapy 2018, 11:4247-4252

Published Date: 23 July 2018

Original Research

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients

Kim HJ, Jo MJ, Kim BR, Kim JL, Jeong YA, Na YJ, Park SH, Lee SY, Lee DH, Kim BH, Yoo YD, Oh SC

OncoTargets and Therapy 2018, 11:4233-4246

Published Date: 23 July 2018

Original Research

CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway

Jia Y, Xiao Z, Gongsun X, Xin Z, Shang B, Chen G, Wang Z, Jiang W

OncoTargets and Therapy 2018, 11:4221-4232

Published Date: 20 July 2018

Original Research

Matrix metalloproteinase-7 may serve as a novel biomarker for cervical cancer

Zhu L, Zheng X, Du Y, Xing Y, Xu K, Cui L

OncoTargets and Therapy 2018, 11:4207-4220

Published Date: 20 July 2018

Original Research

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells

Yang L, Xie N, Huang J, Huang H, Xu S, Wang Z, Cai J

OncoTargets and Therapy 2018, 11:4197-4206

Published Date: 19 July 2018

Original Research

Promoter methylation analysis of CDH1 and p14ARF genes in patients with urothelial bladder cancer

Bayramov B, Gunes S, Buyukalpelli R, Aydın O, Henkel R

OncoTargets and Therapy 2018, 11:4189-4196

Published Date: 19 July 2018

Original Research

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway

Ge H, Liang C, Li Z, An D, Ren S, Yue C, Wu J

OncoTargets and Therapy 2018, 11:4177-4187

Published Date: 19 July 2018

Original Research

Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis

Zheng T, Li D, He Z, Feng S, Zhao S

OncoTargets and Therapy 2018, 11:4167-4175

Published Date: 19 July 2018

Original Research

Expression of protein disulfide isomerase A3 precursor in colorectal cancer

Yang Z, Liu J, Shi Q, Chao Y, Di Y, Sun J, Zhang J, Huang L, Guo H, He C

OncoTargets and Therapy 2018, 11:4159-4166

Published Date: 19 July 2018

Original Research

Efficacy and safety assessment of apatinib in patients with advanced gastric cancer: a meta-analysis

Chen J, Wang J

OncoTargets and Therapy 2018, 11:4149-4158

Published Date: 19 July 2018

Review

Progress in the treatment of solid tumors with apatinib: a systematic review

Zhao D, Hou H, Zhang X

OncoTargets and Therapy 2018, 11:4137-4147

Published Date: 19 July 2018

Original Research

Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma

Xin Z, Xin G, Shi M, Song L, Wang Q, Jiang B, Liu X

OncoTargets and Therapy 2018, 11:4125-4136

Published Date: 19 July 2018

Review

Pleiotropic functions of miR107 in cancer networks

Luo Z, Zheng Y, Zhang W

OncoTargets and Therapy 2018, 11:4113-4124

Published Date: 18 July 2018

Original Research

Identification of potential core genes in triple negative breast cancer using bioinformatics analysis

Li MX, Jin LT, Wang TJ, Feng YJ, Pan CP, Zhao DM, Shao J

OncoTargets and Therapy 2018, 11:4105-4112

Published Date: 18 July 2018

Original Research

TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma

Yu S, Xu T, Dai J, Ma M, Tang H, Chi Z, Si L, Cui C, Sheng X, Kong Y, Guo J

OncoTargets and Therapy 2018, 11:4097-4104

Published Date: 17 July 2018

Original Research

miR-19b serves as a prognostic biomarker of breast cancer and promotes tumor progression through PI3K/AKT signaling pathway

Li C, Zhang J, Ma Z, Zhang F, Yu W

OncoTargets and Therapy 2018, 11:4087-4095

Published Date: 16 July 2018

Original Research

MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42

Gu G, Wang L, Zhang J, Wang H, Tan T, Zhang G

OncoTargets and Therapy 2018, 11:4075-4085

Published Date: 16 July 2018

Original Research

MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9)

Liu R, Wang F, Guo Y, Yang J, Chen S, Gao X, Wang X

OncoTargets and Therapy 2018, 11:4065-4073

Published Date: 16 July 2018

Review

New PDL1 inhibitors for non-small cell lung cancer: focus on pembrolizumab

Bylicki O, Paleiron N, Rousseau-Bussac G, Chouaïd C

OncoTargets and Therapy 2018, 11:4051-4064

Published Date: 16 July 2018

Case report

Long-term progression-free survival of third-line apatinib in lung squamous cell carcinoma

Li X, Li X, Fang X, Yuan Y

OncoTargets and Therapy 2018, 11:4047-4050

Published Date: 16 July 2018

Original Research

MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition

Hu F, Liu C, Xie F, Lin X, Yang J, Wang C, Huang Q

OncoTargets and Therapy 2018, 11:4035-4046

Published Date: 13 July 2018

Case report

Mutational analysis on gastric, duodenal, bone, and mediastinal lymph node metastases and blood from a case of primary lung adenocarcinoma

Yang X, Chen R, Wu C, Zhao W, Ji M

OncoTargets and Therapy 2018, 11:4029-4034

Published Date: 13 July 2018

Original Research

Downregulation and DNA methylation of ECRG4 in gastric cancer

Deng P, Chang XJ, Gao ZM, Xu XY, Sun AQ, Li K, Dai DQ

OncoTargets and Therapy 2018, 11:4019-4028

Published Date: 13 July 2018

Original Research

MFAP2 promotes epithelial–mesenchymal transition in gastric cancer cells by activating TGF-β/SMAD2/3 signaling pathway

Wang JK, Wang WJ, Cai HY, Du BB, Mai P, Zhang LJ, Ma W, Hu YG, Feng SF, Miao GY

OncoTargets and Therapy 2018, 11:4001-4017

Published Date: 12 July 2018

Original Research

The effect of tubeimoside-1 on the proliferation, metastasis and apoptosis of oral squamous cell carcinoma in vitro

Wu T, Cui H, Xu Y, Du Q, Zhao E, Cao J, Nie L, Fu G, Ren A

OncoTargets and Therapy 2018, 11:3989-4000

Published Date: 10 July 2018

Original Research

Overexpressed CDR1as functions as an oncogene to promote the tumor progression via miR-7 in non-small-cell lung cancer

Zhang X, Yang D, Wei Y

OncoTargets and Therapy 2018, 11:3979-3987

Published Date: 10 July 2018

Original Research

Increased expression of antisense lncRNA SPINT1-AS1 predicts a poor prognosis in colorectal cancer and is negatively correlated with its sense transcript

Li C, Li W, Zhang YL, Zhang X, Liu T, Zhang Y, Yang YM, Wang LL, Pan HW, Ji J, Wang CX

OncoTargets and Therapy 2018, 11:3969-3978

Published Date: 10 July 2018

Original Research

SIRT4 acts as a tumor suppressor in gastric cancer by inhibiting cell proliferation, migration, and invasion

Sun H, Huang D, Liu G, Jian F, Zhu J, Zhang L

OncoTargets and Therapy 2018, 11:3959-3968

Published Date: 10 July 2018

Original Research

Immunohistochemical expression of hormone receptors, Ki-67, endoglin (CD105), claudins 3 and 4, MMP -2 and -9 in endometrial polyps and endometrial cancer type I

Peres GF, Spadoto-Dias D, Bueloni-Dias FN, Leite NJ, Elias LV, Domingues MA, Padovani CR, Dias R

OncoTargets and Therapy 2018, 11:3949-3958

Published Date: 9 July 2018

Case report

Role of chemotherapy with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI ) rechallenge in small cell transformation after EGFR-TKI failure: a case report

Lee S, Joo JH, Kwak MA, Sohn K, Chon SH

OncoTargets and Therapy 2018, 11:3943-3947

Published Date: 9 July 2018

Original Research

Overexpression of DJ-1 correlates with aggressive clinicopathological characteristics and poor prognosis in malignant tumors: a meta-analysis

Wang Q, Li F, Shi W, Zhang Q, Wang J, Yan X, Chai L, Li M

OncoTargets and Therapy 2018, 11:3931-3942

Published Date: 9 July 2018

Original Research

Integrated omics and gene expression analysis identifies the loss of metabolite–metabolite correlations in small cell lung cancer

Yu L, Li K, Xu Z, Cui G, Zhang X

OncoTargets and Therapy 2018, 11:3919-3929

Published Date: 6 July 2018

Original Research

Predictive value of single nucleotide polymorphisms in XRCC1 for radiation-induced normal tissue toxicity

Zhao J, Zhi Z, Zhang M, Li Q, Li J, Wang X, Ma C

OncoTargets and Therapy 2018, 11:3901-3918

Published Date: 6 July 2018

Review

MicroRNAs as potential biomarkers for diagnosis, therapy and prognosis of gastric cancer

Yuan HL, Wang T, Zhang KH

OncoTargets and Therapy 2018, 11:3891-3900

Published Date: 6 July 2018

Original Research

The clinical usefulness of natural killer cell activity in patients with suspected or diagnosed prostate cancer: an observational cross-sectional study

Song W, Yu JW, Jeong BC, Seo SI, Jeon SS, Lee HM, Choi HY, Kang ES, Jeon HG

OncoTargets and Therapy 2018, 11:3883-3889

Published Date: 6 July 2018

Original Research

Bortezomib-based therapy for transplant-ineligible East Asian patients with newly diagnosed mantle-cell lymphoma

Jin J, Okamoto R, Yoon SS, Shih LY, Zhu J, Liu T, Hong XN, Pei L, Rooney B, van de Velde H, Huang HQ

OncoTargets and Therapy 2018, 11:3869-3882

Published Date: 6 July 2018

Original Research

Loss of miR-516a-3p mediates upregulation of ABCC5 in prostate cancer and drives its progression

Zhang H, Lian Z, Sun G, Liu R, Xu Y

OncoTargets and Therapy 2018, 11:3853-3867

Published Date: 6 July 2018

Review

The role of histone lysine methyltransferase NSD3 in cancer

Han X, Piao L, Zhuang Q, Yuan X, Liu Z, He X

OncoTargets and Therapy 2018, 11:3847-3852

Published Date: 5 July 2018

Original Research

miR-106b-5p inhibits the invasion and metastasis of colorectal cancer by targeting CTSA

Ni S, Weng W, Xu M, Wang Q, Tan C, Sun H, Wang L, Huang D, Du X, Sheng W

OncoTargets and Therapy 2018, 11:3835-3845

Published Date: 4 July 2018

Original Research

Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2

Wan B, Zang Y, Wang L

OncoTargets and Therapy 2018, 11:3827-3833

Published Date: 4 July 2018

Review

Tumor-associated macrophage-derived cytokines enhance cancer stem-like characteristics through epithelial–mesenchymal transition

Chen Y, Tan W, Wang C

OncoTargets and Therapy 2018, 11:3817-3826

Published Date: 4 July 2018

Original Research

Silencing of c-jun decreases cell migration, invasion, and EMT in radioresistant human nasopharyngeal carcinoma cell line CNE-2R

Lin G, Yu B, Liang Z, Li L, Qu S, Chen K, Zhou L, Lu Q, Sun Y, Zhu X

OncoTargets and Therapy 2018, 11:3805-3815

Published Date: 4 July 2018

Original Research

By blocking hexokinase-2 phosphorylation, limonin suppresses tumor glycolysis and induces cell apoptosis in hepatocellular carcinoma

Yao J, Liu J, Zhao W

OncoTargets and Therapy 2018, 11:3793-3803

Published Date: 3 July 2018

Original Research

A prospective study on neoadjuvant chemoradiotherapy plus anti-EGFR monoclonal antibody followed by surgery for locally advanced cervical cancer

Lu H, Wu Y, Liu X, Jiang H, Pang Q, Peng L, Cheng J, Deng S, Gu J, Zhao R, Hu X, Chen C, Yu J

OncoTargets and Therapy 2018, 11:3785-3792

Published Date: 2 July 2018

Original Research

SIL1 functions as an oncogene in glioma by AKT/mTOR signaling pathway

Xu H, Xu S, Zhang R, Xin T, Pang Q

OncoTargets and Therapy 2018, 11:3775-3783

Published Date: 2 July 2018

Original Research

Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer

Wang S, Zhang Z, Qian W, Ji D, Wang Q, Ji B, Zhang Y, Zhang C, Sun Y, Zhu C, Sun Y

OncoTargets and Therapy 2018, 11:3765-3774

Published Date: 2 July 2018

Review

Colorectal neoplasia differentially expressed: a long noncoding RNA with an imperative role in cancer

Dai M, Li S, Qin X

OncoTargets and Therapy 2018, 11:3755-3763

Published Date: 29 June 2018

Review

Primary effusion lymphoma: current perspectives

Narkhede M, Arora S, Ujjani C

OncoTargets and Therapy 2018, 11:3747-3754

Published Date: 28 June 2018

Review

IRX-2 natural cytokine biologic for immunotherapy in patients with head and neck cancers

Wolf GT, Moyer JS, Kaplan MJ, Newman JG, Egan JE, Berinstein NL, Whiteside TL

OncoTargets and Therapy 2018, 11:3731-3746

Published Date: 28 June 2018

Original Research

Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma

Dong M, Miao L, Zhang F, Li S, Han J, Yu R, Qie S

OncoTargets and Therapy 2018, 11:3721-3729

Published Date: 28 June 2018

Review

Updates on the clinical diagnosis and management of ocular sebaceous carcinoma: a brief review of the literature

Xu YF, Li F, Jia RB, Fan XQ

OncoTargets and Therapy 2018, 11:3713-3720

Published Date: 27 June 2018

Case report

Targeted therapy and immunotherapy for platinum-refractory advanced ovarian adenosquamous carcinoma: a case report

Li A, Sun S, Song T, Li X, Cheng W, Yao R, Zhang D, Cai Z, Zhang J, Zhai D, Yu C

OncoTargets and Therapy 2018, 11:3705-3711

Published Date: 27 June 2018

Original Research

Chemotherapy with or without pemetrexed as second-line regimens for advanced non-small-cell lung cancer patients who have progressed after first-line EGFR TKIs: a systematic review and meta-analysis

Li ZH, Guo HY, Lu YY, Hu JX, Luo HT, Gu WG

OncoTargets and Therapy 2018, 11:3697-3703

Published Date: 27 June 2018

Original Research

Impact of smoking on efficacy of PD-1/PD-L1 inhibitors in non-small cell lung cancer patients: a meta-analysis

Li B, Huang X, Fu L

OncoTargets and Therapy 2018, 11:3691-3696

Published Date: 26 June 2018

Case report

An uncommon granulocytic sarcoma of the breast: a case report and literature review

Zhai J, Kong X, Yang X, Gao J, Xuan L, Wang X, Wang J, Fang Y

OncoTargets and Therapy 2018, 11:3685-3690

Published Date: 25 June 2018

Original Research

CAT3, a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independently of O6-methylguanine DNA methyltransferase expression

Ji M, Wang L, Chen J, Xue N, Wang C, Lai F, Wang R, Yu SS, Jin J, Chen X

OncoTargets and Therapy 2018, 11:3671-3684

Published Date: 25 June 2018

Original Research

Prognostic impact of the number of lymph nodes examined in different stages of colorectal mucinous adenocarcinoma

Ma Y, Luo YQ, Lin N, Lv YZ, Zhou Y, Li B, Han KN, Jiang S, Gao JJ

OncoTargets and Therapy 2018, 11:3659-3670

Published Date: 25 June 2018

Original Research

lincROR influences the stemness and crizotinib resistance in EML–ALK+ non-small-cell lung cancer cells

Yang Y, Huang J, Xie N, Huang H, Xu S, Cai J, Qi S

OncoTargets and Therapy 2018, 11:3649-3657

Published Date: 22 June 2018

Original Research

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma

Wang H, Fang ZL, Zhang GH, Ma X

OncoTargets and Therapy 2018, 11:3637-3647

Published Date: 21 June 2018

Original Research

MYO5A inhibition by miR-145 acts as a predictive marker of occult neck lymph node metastasis in human laryngeal squamous cell carcinoma

Zhao X, Zhang W, Ji W

OncoTargets and Therapy 2018, 11:3619-3635

Published Date: 21 June 2018

Original Research

A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1

Zhao XZ, Wu XH

OncoTargets and Therapy 2018, 11:3609-3617

Published Date: 21 June 2018

Original Research

Whole-body MRI versus 18F-FDG PET/CT for pretherapeutic assessment and staging of lymphoma: a meta-analysis

Wang D, Huo Y, Chen S, Wang H, Ding Y, Zhu X, Ma C

OncoTargets and Therapy 2018, 11:3597-3608

Published Date: 20 June 2018

Original Research

lncRNA H19 predicts poor prognosis in patients with melanoma and regulates cell growth, invasion, migration and epithelial–mesenchymal transition in melanoma cells

Shi G, Li H, Gao F, Tan Q

OncoTargets and Therapy 2018, 11:3583-3595

Published Date: 20 June 2018

Original Research

Impact of RNA integrity and blood sample storage conditions on the gene expression analysis

Shen YT, Li R, Tian F, Chen ZZ, Lu N, Bai YF, Ge QY, Lu ZH

OncoTargets and Therapy 2018, 11:3573-3581

Published Date: 20 June 2018

Original Research

Clinicopathological and prognostic significance of FoxM1 in hepatocellular carcinoma patients: a meta-analysis

Liang C, Zhao J, Ge H, Li G, Wu J

OncoTargets and Therapy 2018, 11:3561-3571

Published Date: 19 June 2018

Original Research

The role of radioactive iodine therapy in papillary thyroid cancer: an observational study based on SEER

Tang J, Kong D, Cui Q, Wang K, Zhang D, Liao X, Gong Y, Wu G

OncoTargets and Therapy 2018, 11:3551-3560

Published Date: 19 June 2018

Original Research

Prognostic value of miR-17-5p in cancers: a meta-analysis

Kong W, Cheng Y, Liang H, Chen Q, Xiao C, Li K, Huang Z, Zhang J

OncoTargets and Therapy 2018, 11:3541-3549

Published Date: 19 June 2018

Review

Multiple biological functions of transcription factor 21 in the development of various cancers

Jiang X, Yang Z

OncoTargets and Therapy 2018, 11:3533-3539

Published Date: 19 June 2018

Original Research

Curcumin suppresses the progression of laryngeal squamous cell carcinoma through the upregulation of miR-145 and inhibition of the PI3K/Akt/mTOR pathway

Zhu X, Zhu R

OncoTargets and Therapy 2018, 11:3521-3531

Published Date: 19 June 2018

Original Research

The prognosis for patients with newly diagnosed glioblastoma receiving bevacizumab combination therapy: a meta-analysis

Liao KL, Huang S, Wu YP

OncoTargets and Therapy 2018, 11:3513-3520

Published Date: 19 June 2018

Review

Combined small-cell lung carcinoma

Qin J, Lu H

OncoTargets and Therapy 2018, 11:3505-3511

Published Date: 19 June 2018

Original Research

Association between common polymorphisms in ERCC gene and prognosis of osteosarcoma in patients treated with chemotherapy: a meta-analysis

Li C, Yu X, Guo D, Liu G, Zhang K, Teng Q, Lin H

OncoTargets and Therapy 2018, 11:3495-3504

Published Date: 18 June 2018

Original Research

Downregulation of ribophorin II suppresses tumor growth, migration, and invasion of nasopharyngeal carcinoma

Hong F, Li Y, Ni H, Li J

OncoTargets and Therapy 2018, 11:3485-3494

Published Date: 15 June 2018

Original Research

STAT3 induces colorectal carcinoma progression through a novel miR-572-MOAP-1 pathway

Wang N, He X, Zhou R, Jia G, Qiao Q

OncoTargets and Therapy 2018, 11:3475-3484

Published Date: 15 June 2018

Original Research

MALAT1 silencing suppresses prostate cancer progression by upregulating miR-1 and downregulating KRAS

Chang J, Xu W, Du X, Hou J

OncoTargets and Therapy 2018, 11:3461-3473

Published Date: 15 June 2018

Original Research

The association of pretreatment serum albumin with outcomes in bladder cancer: a meta-analysis

Li J, Cheng Y, Liu G, Ji Z

OncoTargets and Therapy 2018, 11:3449-3459

Published Date: 15 June 2018

Original Research

Comparison of the prognosis of neoadjuvant chemoradiotherapy treatment with surgery alone in esophageal carcinoma: a meta-analysis

Ma HF, Lv GX, Cai ZF, Zhang DH

OncoTargets and Therapy 2018, 11:3441-3447

Published Date: 14 June 2018

Original Research

Effectiveness of lomustine and bevacizumab in progressive glioblastoma: a meta-analysis

Song J, Xue YQ, Zhao MM, Xu P

OncoTargets and Therapy 2018, 11:3435-3439

Published Date: 13 June 2018

Review

Reformulating acute myeloid leukemia: liposomal cytarabine and daunorubicin (CPX-351) as an emerging therapy for secondary AML

Chen EC, Fathi AT, Brunner AM

OncoTargets and Therapy 2018, 11:3425-3434

Published Date: 12 June 2018

Original Research

Twenty-gene-based prognostic model predicts lung adenocarcinoma survival

Zhao K, Li Z, Tian H

OncoTargets and Therapy 2018, 11:3415-3424

Published Date: 12 June 2018

Original Research

Efficacy and safety of sorafenib versus apatinib in the treatment of intermediate and advanced hepatocellular carcinoma: a comparative retrospective study

Wang Y, Gou Q, Xu R, Chen X, Zhou Z

OncoTargets and Therapy 2018, 11:3407-3413

Published Date: 12 June 2018

Original Research

Identification of CD24 as a marker for tumorigenesis of melanoma

Tang MR, Guo JY, Wang D, Xu N

OncoTargets and Therapy 2018, 11:3401-3406

Published Date: 12 June 2018

Review

Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer

Huang G, Zhu G

OncoTargets and Therapy 2018, 11:3395-3400

Published Date: 11 June 2018

Original Research

Expression and functional characterization of FOXM1 in non-small cell lung cancer

Zhang Y, Qiao W, Shan L

OncoTargets and Therapy 2018, 11:3385-3393

Published Date: 11 June 2018

Original Research

Prognostic value of spleen tyrosine kinase in human solid tumors

Ni B, Li S, Liu Y, Huang Y, Li Z

OncoTargets and Therapy 2018, 11:3377-3384

Published Date: 8 June 2018

Original Research

Meta-analysis of segmentectomy versus wedge resection in stage IA non-small-cell lung cancer

Xue WF, Duan GC, Zhang XP, Zhang H, Zhao QT, Xin ZF

OncoTargets and Therapy 2018, 11:3369-3375

Published Date: 7 June 2018

Original Research

Effect of AQP-5 silencing by siRNA interference on chemosensitivity of breast cancer cells

Li X, Pei B, Wang H, Tang C, Zhu W, Jin F

OncoTargets and Therapy 2018, 11:3359-3368

Published Date: 6 June 2018

Original Research

Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics

Liu X, Weng Y, Liu P, Sui Z, Zhou L, Huang Y, Zhang L, Zhang Y, Tan X

OncoTargets and Therapy 2018, 11:3345-3357

Published Date: 6 June 2018

Original Research

Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer

Kobayashi K, Naoki K, Manabe T, Masuzawa K, Hasegawa H, Yasuda H, Kawada I, Soejima K, Betsuyaku T

OncoTargets and Therapy 2018, 11:3335-3343

Published Date: 6 June 2018

Original Research

Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling

Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y, Kan Q

OncoTargets and Therapy 2018, 11:3323-3333

Published Date: 6 June 2018

Original Research

Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway

Al-Obeed O, Vaali-Mohammed MA, Eldehna WM, Al-Khayal K, Mahmood A, Abdel-Aziz HA, Zubaidi A, Alafeefy A, Abdulla M, Ahmad R

OncoTargets and Therapy 2018, 11:3313-3322

Published Date: 5 June 2018

Original Research

Overexpression of CLEC3A promotes tumor progression and poor prognosis in breast invasive ductal cancer

Ni J, Peng Y, Yang F, Xi X, Huang X, He C

OncoTargets and Therapy 2018, 11:3303-3312

Published Date: 5 June 2018

Original Research

Effects of the combination of As2O3 and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1

Zhao C, Wang M, Liu Y, Liang YJ, Han L, Chen C

OncoTargets and Therapy 2018, 11:3293-3301

Published Date: 1 June 2018

Original Research

Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1

Chen Y, Zhang F, Zhao Y, He K, Zheng X, Pan Y, Shao D, Shang P, Yang Y, Zhang D, Xie Y, Yao X, Chen L, Li J, Zhang X

OncoTargets and Therapy 2018, 11:3281-3292

Published Date: 1 June 2018

Original Research

Association of VDR gene TaqI polymorphism with the susceptibility to prostate cancer in Asian population evaluated by an updated systematic meta-analysis

Chen L, Wei J, Zhang S, Lou Z, Wang X, Ren Y, Qi H, Xie Z, Chen Y, Chen F, Wu Q, Fan X, Xu H, Huang S, Weng G

OncoTargets and Therapy 2018, 11:3267-3280

Published Date: 31 May 2018

Original Research

A new apatinib microcrystal formulation enhances the effect of radiofrequency ablation treatment on hepatocellular carcinoma

Xie H, Tian S, Yu H, Yang X, Liu J, Wang H, Feng F, Guo Z

OncoTargets and Therapy 2018, 11:3257-3265

Published Date: 31 May 2018

Review

Prognostic role of plasma mammaglobin A expression in breast carcinoma patients: a meta-analysis

Hu YY, Liu P, Wu D, Jiang YH

OncoTargets and Therapy 2018, 11:3245-3255

Published Date: 30 May 2018

Original Research

Prognostic significance of galectin-1 and vasculogenic mimicry in patients with gastric cancer

You X, Wang Y, Wu J, Liu Q, Chen D, Tang D, Wang D

OncoTargets and Therapy 2018, 11:3237-3244

Published Date: 29 May 2018

Original Research

Association between KIF1B (rs17401966) polymorphism and hepatocellular carcinoma susceptibility: a meta-analysis

Zhang Y, Zeng X, Lu H, Ji H, Lu L, Liu P, Hong R, Li Y

OncoTargets and Therapy 2018, 11:3225-3235

Published Date: 29 May 2018

Original Research

Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression

Li S, Wen D, Che S, Cui Z, Sun Y, Ren H, Hao J

OncoTargets and Therapy 2018, 11:3215-3223

Published Date: 6 June 2018

Original Research

Periostin overexpression is associated with worse prognosis in nasopharyngeal carcinoma from endemic area: a cohort study

Wei YC, Yang SF, Chang SL, Chen TJ, Lee SW, Chen HS, Lin LC, Li CF

OncoTargets and Therapy 2018, 11:3205-3213

Published Date: 29 May 2018

Original Research

Knockdown of KIF26B inhibits breast cancer cell proliferation, migration, and invasion

Gu S, Liang H, Qi D, Mao L, Mao G, Qian L, Zhang S

OncoTargets and Therapy 2018, 11:3195-3203

Published Date: 29 May 2018

Review

Emerging role of long non-coding RNAs in cisplatin resistance

Hu Y, Zhu QN, Deng JL, Li ZX, Wang G, Zhu YS

OncoTargets and Therapy 2018, 11:3185-3194

Published Date: 28 May 2018

Case report

A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature

Duan M, Xing H, Wang K, Niu C, Jiang C, Zhang L, Ezzat S, Zhang L

OncoTargets and Therapy 2018, 11:3179-3184

Published Date: 28 May 2018

Review

Recent advances on the progressive mechanism and therapy in castration-resistant prostate cancer

Wang K, Ruan H, Xu T, Liu L, Liu D, Yang H, Zhang X, Chen K

OncoTargets and Therapy 2018, 11:3167-3178

Published Date: 28 May 2018

Original Research

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells

Wang Z, Luo C, Wang H, Yan X, Liu W, Meng Z

OncoTargets and Therapy 2018, 11:3159-3166

Published Date: 28 May 2018

Original Research

High SRPX2 protein expression predicts unfavorable clinical outcome in patients with prostate cancer

Zhang M, Li X, Fan Z, Zhao J, Liu S, Zhang M, Li H, Goscinski MA, Fan H, Suo Z

OncoTargets and Therapy 2018, 11:3149-3157

Published Date: 28 May 2018

Original Research

miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells

Chen K, Chen Y, Chen Z, Shi Y, He Z, Ding B, Wang C, Yu L

OncoTargets and Therapy 2018, 11:3141-3147

Published Date: 25 May 2018

Original Research

Construction of a specific SVM classifier and identification of molecular markers for lung adenocarcinoma based on lncRNA-miRNA-mRNA network

Zhao J, Cheng W, He X, Liu Y, Li J, Sun J, Li J, Wang F, Gao Y

OncoTargets and Therapy 2018, 11:3129-3140

Published Date: 25 May 2018

Original Research

The incidence and predictors of symptomatic venous thromboembolism associated with peripherally inserted central catheters in patients with nasopharyngeal carcinoma

Liang YJ, He Y, Li JM, Chen LM, Chen LP, Wang C, Ji L, Li ZX, Tang LQ, Chen QY, Fan YY, Hu W

OncoTargets and Therapy 2018, 11:3119-3127

Published Date: 25 May 2018

Original Research

Overexpression of MCPH1 inhibits the migration and invasion of lung cancer cells

Wu X, Liu W, Liu X, Ai Q, Yu J

OncoTargets and Therapy 2018, 11:3111-3117

Published Date: 25 May 2018

Original Research

Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma

Lin MH, Lv D, Zheng YL, Wu ML, Xu C, Zhang Q, Wu LH

OncoTargets and Therapy 2018, 11:3101-3110

Published Date: 25 May 2018

Original Research

Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis

Liu X, Zhao Y, Zhang W, Gao Y, Huo M, Liu M, Xiao Z, Liang S, Xu N, Zhu H

OncoTargets and Therapy 2018, 11:3087-3100

Published Date: 24 May 2018

Original Research

An integrated analysis of key microRNAs, regulatory pathways and clinical relevance in bladder cancer

Li D, Hao X, Song Y

OncoTargets and Therapy 2018, 11:3075-3085

Published Date: 24 May 2018

Original Research

Gene expression and prognosis of NOX family members in gastric cancer

You X, Ma M, Hou G, Hu Y, Shi X

OncoTargets and Therapy 2018, 11:3065-3074

Published Date: 24 May 2018

Original Research

Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic colorectal cancer

Cicero G, De Luca R, Dieli F

OncoTargets and Therapy 2018, 11:3059-3063

Published Date: 24 May 2018

Original Research

The synergistic effects of Apatinib combined with cytotoxic chemotherapeutic agents on gastric cancer cells and in a fluorescence imaging gastric cancer xenograft model

Feng JH, Qin SK

OncoTargets and Therapy 2018, 11:3047-3057

Published Date: 24 May 2018

Original Research

High expression of USP22 predicts poor prognosis and advanced clinicopathological features in solid tumors: a meta-analysis

Yang XH, Zang H, Luo Y, Wu J, Fang Z, Zhu W, Li Y

OncoTargets and Therapy 2018, 11:3035-3046

Published Date: 23 May 2018

Original Research

LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway

Ke J, Ma P, Chen J, Qin J, Qian H

OncoTargets and Therapy 2018, 11:3025-3033

Published Date: 22 May 2018

Original Research

Expression of HSP90AA1/HSPA8 in hepatocellular carcinoma patients with depression

Xiang X, You XM, Li LQ

OncoTargets and Therapy 2018, 11:3013-3023

Published Date: 22 May 2018

Review

The role of HIF-1α in chemo-/radioresistant tumors

Xia Y, Jiang L, Zhong T

OncoTargets and Therapy 2018, 11:3003-3011

Published Date: 22 May 2018

Original Research

The methylation profiles of PRDM promoters in non–small cell lung cancer

Tan SX, Hu RC, Xia Q, Tan YL, Liu JJ, Gan GX, Wang LL

OncoTargets and Therapy 2018, 11:2991-3002

Published Date: 22 May 2018

Original Research

Resveratrol inhibits the proliferation of A549 cells by inhibiting the expression of COX-2

Li X, Li F, Wang FF, Li JF, Lin CZ, Du JX

OncoTargets and Therapy 2018, 11:2981-2989

Published Date: 22 May 2018

Original Research

Intra-arterial chemotherapy improved survival of stage 2–3 gallbladder cancer after curative resection

Chen C, Feng W, Zheng Y, Bao Y, Feng M

OncoTargets and Therapy 2018, 11:2975-2979

Published Date: 22 May 2018

Original Research

Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma

Liu J, Wu Q, Wang Y, Wei Y, Wu H, Duan L, Zhang Q, Wu Y

OncoTargets and Therapy 2018, 11:2963-2973

Published Date: 22 May 2018

Original Research

Downregulation of STARD8 in gastric cancer and its involvement in gastric cancer progression

Zhang S, Chang X, Ma J, Chen J, Zhi Y, Li Z, Dai D

OncoTargets and Therapy 2018, 11:2955-2961

Published Date: 21 May 2018

Original Research

Triclosan treatment decreased the antitumor effect of sorafenib on hepatocellular carcinoma cells

Wu M, Zhao G, Zhuang X, Zhang T, Zhang C, Zhang W, Zhang Z

OncoTargets and Therapy 2018, 11:2945-2954

Published Date: 18 May 2018

Original Research

Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells

Li Z, Zhu C, An B, Chen Y, He X, Qian L, Lan L, Li S

OncoTargets and Therapy 2018, 11:2937-2944

Published Date: 18 May 2018

Original Research

Downregulation of PDIA3 inhibits proliferation and invasion of human acute myeloid leukemia cells

Ye Q, Fu P, Dou J, Wang N

OncoTargets and Therapy 2018, 11:2925-2935

Published Date: 17 May 2018

Original Research

miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R

Liu N, Yang H, Wang H

OncoTargets and Therapy 2018, 11:2911-2923

Published Date: 17 May 2018

Original Research

High neutrophil to lymphocyte ratio and decreased CD69+NK cells represent a phenotype of high risk in early-stage breast cancer patients

Mandó P, Rizzo M, Roberti MP, Juliá EP, Pampena MB, Pérez de la Puente C, Loza CM, Ponce C, Nadal J, Coló FA, Mordoh J, Levy EM

OncoTargets and Therapy 2018, 11:2901-2910

Published Date: 17 May 2018

Original Research

Bacillus Calmette–Guérin and anti-PD-L1 combination therapy boosts immune response against bladder cancer

Wang Y, Liu J, Yang X, Liu Y, Liu Y, Li Y, Sun L, Yang X, Niu H

OncoTargets and Therapy 2018, 11:2891-2899

Published Date: 16 May 2018

Original Research

RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway

Li C, Jiang X, Lin B, Hong H, Zhu S, Jiang L, Wang X, Tang N, She F, Chen Y

OncoTargets and Therapy 2018, 11:2875-2890

Published Date: 16 May 2018

Review

Leaflet manual of external beam radiation therapy for hepatocellular carcinoma: a review of the indications, evidences, and clinical trials

Rim CH, Yoon WS

OncoTargets and Therapy 2018, 11:2865-2874

Published Date: 16 May 2018

Original Research

circSMAD2 inhibits the epithelial–mesenchymal transition by targeting miR-629 in hepatocellular carcinoma

Zhang XW, Luo P, Jing W, Zhou H, Liang CZ, Tu JC

OncoTargets and Therapy 2018, 11:2853-2863

Published Date: 16 May 2018

Original Research

NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation

Li T, Sun R, Lu MD, Chang J, Meng X, Wu H

OncoTargets and Therapy 2018, 11:2843-2852

Published Date: 15 May 2018

Review

Advances of exosome in the development of ovarian cancer and its diagnostic and therapeutic prospect

Shen J, Zhu X, Fei J, Shi P, Yu S, Zhou J

OncoTargets and Therapy 2018, 11:2831-2841

Published Date: 15 May 2018

Original Research

Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis

Zhou X, Huang X, Liang S, Tang S, Wu S, Huang T, Mo Z, Wang Q

OncoTargets and Therapy 2018, 11:2815-2830

Published Date: 15 May 2018

Original Research

5-Azacytidine treatment induces demethylation of DAPK1 and MGMT genes and inhibits growth in canine mammary gland tumor cells

Ren XL, Li HT, Song XY, Wu YH, Liu Y

OncoTargets and Therapy 2018, 11:2805-2813

Published Date: 15 May 2018

Original Research

Long noncoding RNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression

Diao L, Wang S, Sun Z

OncoTargets and Therapy 2018, 11:2797-2804

Published Date: 14 May 2018

Original Research

Impact of targeting transforming growth factor β-2 with antisense OT-101 on the cytokine and chemokine profile in patients with advanced pancreatic cancer

D'Cruz OJ, Qazi S, Hwang L, Ng K, Trieu V

OncoTargets and Therapy 2018, 11:2779-2796

Published Date: 14 May 2018

Original Research

Peritoneal carcinomatosis index as a predictor of diaphragmatic involvement in stage III and IV ovarian cancer

Llueca A, Serra A, Herraiz JL, Rivadulla I, Gomez-Quiles L, Gilabert-Estelles J, Escrig J

OncoTargets and Therapy 2018, 11:2771-2777

Published Date: 15 May 2018

Original Research

ZNF418 overexpression protects against gastric carcinoma and prompts a good prognosis

Hui H, Hu Z, Jiang C, Wu J, Gao Y, Wang X

OncoTargets and Therapy 2018, 11:2763-2770

Published Date: 11 May 2018

Original Research

Upregulation of circ_0066444 promotes the proliferation, invasion, and migration of gastric cancer cells

Rong D, Dong C, Fu K, Wang H, Tang W, Cao H

OncoTargets and Therapy 2018, 11:2753-2761

Published Date: 11 May 2018

Original Research

Leucine-rich alpha-2-glycoprotein-1 is up-regulated in colorectal cancer and is a tumor promoter

Zhang Q, Huang R, Tang Q, Yu Y, Huang Q, Chen Y, Wang G, Wang X

OncoTargets and Therapy 2018, 11:2745-2752

Published Date: 11 May 2018

Original Research

Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo

Ling Z, Guan H, You Z, Wang C, Hu L, Zhang L, Wang Y, Chen S, Xu B, Chen M

OncoTargets and Therapy 2018, 11:2735-2743

Published Date: 11 May 2018

Original Research

Association between angiogenesis and cytotoxic signatures in the tumor microenvironment of gastric cancer

Feng Y, Dai Y, Gong Z, Cheng JN, Zhang L, Sun C, Zeng X, Jia Q, Zhu B

OncoTargets and Therapy 2018, 11:2725-2733

Published Date: 10 May 2018

Original Research

Association between NR5A2 and the risk of pancreatic cancer, especially among Caucasians: a meta-analysis of case–control studies

Chen Q, Yuan H, Shi GD, Wu Y, Liu D, Lin YT, Chen L, Ge W, Jiang K, Miao Y

OncoTargets and Therapy 2018, 11:2709-2723

Published Date: 9 May 2018

Original Research

Clinical relevance of lysyl oxidase-like 2 and functional mechanisms in glioma

Du XG, Zhu MJ

OncoTargets and Therapy 2018, 11:2699-2708

Published Date: 9 May 2018

Original Research

Traditional Chinese medicine Astragalus polysaccharide enhanced antitumor effects of the angiogenesis inhibitor apatinib in pancreatic cancer cells on proliferation, invasiveness, and apoptosis

Wu J, Wang J, Su Q, Ding W, Li T, Yu J, Cao B

OncoTargets and Therapy 2018, 11:2685-2698

Published Date: 9 May 2018

Original Research

Delivery of bevacizumab by intracranial injection: assessment in glioma model

Liu YX, Liu WJ, Zhang HR, Zhang ZW

OncoTargets and Therapy 2018, 11:2673-2683

Published Date: 8 May 2018

Original Research

Influence of different ex vivo cell culture methods on the proliferation and anti-tumor activity of cytokine-induced killer cells from gastric cancer patients

Shi B, Sun AX, Zhang XR

OncoTargets and Therapy 2018, 11:2657-2672

Published Date: 8 May 2018

Original Research

Effect of first-line endocrine therapy in patients with hormone-sensitive advanced breast cancer: a network meta-analysis

Zhang T, Feng F, Zhao W, Tian J, Yao Y, Zhou C, Dong S, Wang C, Zang C, Lv Q, Sun C

OncoTargets and Therapy 2018, 11:2647-2656

Published Date: 8 May 2018

Original Research

The utilization of next-generation sequencing to detect somatic mutations and predict clinical prognosis of Chinese non-small cell lung cancer patients

Cao L, Long L, Li M, Yang H, Deng P, Mao X, Xiang J, Li B, Zhang T, Hu C

OncoTargets and Therapy 2018, 11:2637-2646

Published Date: 8 May 2018

Original Research

Predicting initial margin status in breast cancer patients during breast-conserving surgery

Pan Z, Zhu L, Li Q, Lai J, Peng J, Su F, Li S, Chen K

OncoTargets and Therapy 2018, 11:2627-2635

Published Date: 8 May 2018

Review

Are ovarian cancer stem cells the target for innovative immunotherapy?

Wang L, Xu T, Cui M

OncoTargets and Therapy 2018, 11:2615-2626

Published Date: 8 May 2018

Original Research

A 5-serum miRNA panel for the early detection of colorectal cancer

Guo S, Zhang J, Wang B, Zhang B, Wang X, Huang L, Liu H, Jia B

OncoTargets and Therapy 2018, 11:2603-2614

Published Date: 8 May 2018

Original Research

Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells

Wu S, Yang Y, Li F, Huang L, Han Z, Wang G, Yu H, Li H

OncoTargets and Therapy 2018, 11:2593-2601

Published Date: 8 May 2018

Original Research

WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling

Han Q, Kremerskothen J, Lin X, Zhang X, Rong X, Zhang D, Wang E

OncoTargets and Therapy 2018, 11:2581-2591

Published Date: 8 May 2018

Original Research

Partial stereotactic ablative boost radiotherapy in bulky non-small cell lung cancer: a retrospective study

Bai Y, Gao XS, Qin SB, Chen JY, Su MM, Liu Q, Qin XB, Ma MW, Zhao B, Gu XB, Xie M, Cui M, Qi X, Li XY

OncoTargets and Therapy 2018, 11:2571-2579

Published Date: 8 May 2018

Case Series

Fatal hemoptysis in patients with advanced esophageal cancer treated with apatinib

Wang W, Zhang L, Xie Y, Zhen TC, Su GZ, Zang Q

OncoTargets and Therapy 2018, 11:2565-2570

Published Date: 7 May 2018

Case report

Perioperative chemotherapy with pemetrexed and cisplatin for pulmonary large-cell neuroendocrine carcinoma: a case report and literature review

Tang H, Wang HY, Xi SY, He CY, Chang YX, Wang QM, Wu YF

OncoTargets and Therapy 2018, 11:2557-2563

Published Date: 7 May 2018

Original Research

Patterns of local failures and suggestions for reduction of clinical target volume for nasopharyngeal carcinoma patients without cervical lymph node metastasis

Li Y, Ou X, Shen C, Xu T, Li W, Hu C

OncoTargets and Therapy 2018, 11:2545-2555

Published Date: 7 May 2018