Cancer Management and Research

Primary Testicular Lymphoma with Central Nervous System Relapse Was Successfully Treated by a Chemo-Free Regimen: A Case Report and Literature Review

Yan Z, Yao S, Wang Y, Liu Y, Yao Z

Cancer Management and Research 2021, 13:9489-9500

Published Date: 31 December 2021

Prognostic Significance of CCNB2 Expression in Triple-Negative Breast Cancer

Cao J, Sun S, Min R, Li R, Fan X, Han Y, Feng Z, Li N

Cancer Management and Research 2021, 13:9477-9487

Published Date: 31 December 2021

Upregulated Expression of Actin-Like 6A is a Risk Factor Affecting the Prognosis of Pancreatic Cancer

Zhang Z, Guo H, Zhang H

Cancer Management and Research 2021, 13:9467-9475

Published Date: 30 December 2021

Partial Breast Reconstruction with Lateral Chest Wall Perforator Flap to Facilitate Breast Conservation in Breast Cancer: First 100 Cases with Cancer Outcomes at 8 Years Follow-Up and the Lessons Learned

Roy PG, Mustata L, Hu J, Phillips B, Parulekar V, Bhattacharyya M, Harris A, Oliveros S

Cancer Management and Research 2021, 13:9453-9466

Published Date: 30 December 2021

Hsa_circ_0007637 Facilitates Nasopharyngeal Carcinoma Progression by Sponging miR-636/TPD52 Axis

Wang Y, Li M, Pan C, Huang H, Hu X, Liu J

Cancer Management and Research 2021, 13:9439-9452

Published Date: 30 December 2021

Anatomical Resection Improves Disease-Free Survival After Lung Metastasectomy of Colorectal Cancer

Liu T, Chang W, Wang H, Lin Q, Wei Y, Tang W, Liu Y, Chen Y, Niu Z, Jiang Y, Ren L, Xu J

Cancer Management and Research 2021, 13:9429-9437

Published Date: 30 December 2021

Diagnosis and Treatment of Renal Cell Carcinoma During Pregnancy

Xu H, Tan S

Cancer Management and Research 2021, 13:9423-9428

Published Date: 29 December 2021

Regulation of RUNX3 Expression by DNA Methylation in Prostate Cancer [Retraction]

Yang X, Wang S, Reheman A

Cancer Management and Research 2021, 13:9421-9422

Published Date: 30 December 2021

Association Between Neutrophil-Lymphocyte Ratio and Oncotype Dx Recurrence Score in Early-Stage Hormonal Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer

Alshamsan B, Alshibany A, Elshenawy MA, Badran A, Elhassan T, Ajarim D, Alsayed A, Suleman K, Al-Tweigeri T

Cancer Management and Research 2021, 13:9411-9420

Published Date: 29 December 2021

Precancerous Lesions of the Cervix and Associated Factors among Women of East Gojjam, Northwest Ethiopia, 2020

Getinet M, Taye M, Ayinalem A, Gitie M

Cancer Management and Research 2021, 13:9401-9410

Published Date: 29 December 2021

Nomogram Predicting Overall Survival in Patients with FIGO II to III Squamous Cell Cervical Carcinoma Under Radical Radiotherapy: A Retrospective Analysis Based on 2018 FIGO Staging

Zang L, Chen Q, Zhang X, Zhong X, Chen J, Fang Y, Lin A, Wang M

Cancer Management and Research 2021, 13:9391-9400

Published Date: 29 December 2021

Real-Life Clinical Data of Lenvatinib versus Sorafenib for Unresectable Hepatocellular Carcinoma in Italy

Burgio V, Iavarone M, Di Costanzo GG, Marra F, Lonardi S, Tamburini E, Piscaglia F, Masi G, Celsa C, Foschi FG, Silletta M, Amoruso DC, Rimini M, Bruccoleri M, Tortora R, Campani C, Soldà C, Viola MG, Forgione A, Conti F, Salani F, Catanese S, Giacchetto CM, Fulgenzi C, Coppola C, Lampertico P, Pellino A, Rancatore G, Cabibbo G, Ratti F, Pedica F, Della Corte A, Colombo M, De Cobelli F, Aldrighetti L, Cascinu S, Casadei-Gardini A

Cancer Management and Research 2021, 13:9379-9389

Published Date: 24 December 2021

Development of a Prognostic Nomogram in Hepatocellular Carcinoma with Portal Vein Tumor Thrombus Following Trans-Arterial Chemoembolization with Drug-Eluting Beads

Cheng S, Yu X, Liu S, Jin Z, Xue H, Wang Z, Xie P

Cancer Management and Research 2021, 13:9367-9377

Published Date: 24 December 2021

Prognostic Implication of Metabolic Syndrome in Patients with Nasopharyngeal Carcinoma: A Large Institution-Based Cohort Study from an Endemic Area

Huang S, Tan X, Feng P, Gong S, He Q, Zhu X, Liu N, Li Y

Cancer Management and Research 2021, 13:9355-9366

Published Date: 24 December 2021

The lncRNA HOXA11-AS Regulates Rab3D Expression by Sponging miR-125a-5p Promoting Metastasis of Osteosarcoma [Corrigendum]

Cao K, Fang Y, Wang H, Jiang Z, Guo L, Hu Y

Cancer Management and Research 2021, 13:9351-9353

Published Date: 23 December 2021

Knockdown of Hsa_circ_0000729 Inhibits the Tumorigenesis of Non-Small Cell Lung Cancer Through Mediation of miR-1281/FOXO3 Axis [Retraction]

Xie X, Ding F, Xiao H

Cancer Management and Research 2021, 13:9349-9350

Published Date: 23 December 2021

LINC00908 Promotes Diffuse Large B-Cell Lymphoma Development by Down-Regulating miR-671-5p [Retraction]

Zeng H, Wei Y, Wei X, Feng R

Cancer Management and Research 2021, 13:9347-9348

Published Date: 23 December 2021

Circular RNA Circ_0025033 Promotes the Evolvement of Ovarian Cancer Through the Regulation of miR-330-5p/KLK4 Axis [Retraction]

Cheng H, Wang N, Tian J, Li Y, Ren L, Shi Z

Cancer Management and Research 2021, 13:9345-9346

Published Date: 23 December 2021

The Circadian Gene NPAS2 Act as a Putative Tumor Stimulative Factor for Uterine Corpus Endometrial Carcinoma

Zheng X, Lv X, Zhu L, Xu K, Shi C, Cui L, Ding H

Cancer Management and Research 2021, 13:9329-9343

Published Date: 22 December 2021

Original Research

Use of Skin Testing Screening and Desensitization Before the First Exposure of Rituximab

Li L, Wang L, Guan K, Liu J, Zhou D, Zhang Y, Zhang Y

Cancer Management and Research 2021, 13:9319-9328

Published Date: 22 December 2021

Plasma Endoglin is Associated with Favorable Outcome for Pemetrexed-Based Therapy in Advanced Non-Small Cell Lung Cancer

Li CH, Ko JL, Hsiao YP, Tsai MH, Lai YC, Hsin IL, Kang YT, Sheu GT, Lin WL, Wu MF

Cancer Management and Research 2021, 13:9305-9318

Published Date: 22 December 2021

Enhanced Efficacy of Neoadjuvant Chemotherapy with Nab-Paclitaxel and Platinum for Locally Advanced Cervical Cancer

Yu XL, Wu MF, Ding L, Yang J, Bai SM

Cancer Management and Research 2021, 13:9297-9304

Published Date: 22 December 2021

Validity and Reliability of the Amharic Version of EORTC-QLQ-CR29 Among Colorectal Cancer Patients in Ethiopia

Abebe LG, Wondimagegnehu A, Woldemariam AA, Gelaye B, Kantelhardt EJ, Addissie A

Cancer Management and Research 2021, 13:9287-9295

Published Date: 21 December 2021

Development and External Validation of a Nomogram to Predict Cancer-Specific Survival in Patients with Primary Intestinal Non-Hodgkin Lymphomas

Zhang C, Liu Z, Tao J, Lin L, Zhai L

Cancer Management and Research 2021, 13:9271-9285

Published Date: 20 December 2021

Prognosis Value of microRNA-3677-3p in Lung Adenocarcinoma and Its Regulatory Effect on Tumor Progression

Zhao J, Yu H, Han T, Zhu X

Cancer Management and Research 2021, 13:9261-9270

Published Date: 18 December 2021

Efficacy and Safety of Local Radiotherapy to All Oligometastatic Sites in Elderly Patients with Metachronous Oligometastatic Cancers After Initial Treatment for the Primary Tumor

Hu X, Li H, Kang X, Wang X, Pang H, Liu C, Zhang J, Wang Y

Cancer Management and Research 2021, 13:9247-9259

Published Date: 18 December 2021

Clinical and Therapeutic Factors Vary by Prognosis in Patients with Pathological Complete Response After Neoadjuvant Therapy for Breast Cancer

Huang Z, Jin S, Zeng M, Shu J, Liu Y, Zhang J, Xu B, Niu M, Sun S, Nanding A, Shan M, Li X, Zhang G

Cancer Management and Research 2021, 13:9235-9246

Published Date: 18 December 2021

Survival and Predictors of Mortality among Breast Cancer Patients in Northwest Ethiopia: A Retrospective Cohort Study

Tiruneh M, Tesfaw A, Tesfa D

Cancer Management and Research 2021, 13:9225-9234

Published Date: 16 December 2021

Intra-Tumor Heterogeneity of Colorectal Cancer Necessitates the Multi-Regional Sequencing for Comprehensive Mutational Profiling

Guo S, Ye Y, Liu X, Gong Y, Xu M, Song L, Liu H

Cancer Management and Research 2021, 13:9209-9223

Published Date: 16 December 2021

Analysis of Cases ofCervical Cancer in Pregnant Women

Bo D, Liu J, Li Y, Wang J, Wang Y

Cancer Management and Research 2021, 13:9201-9208

Published Date: 14 December 2021

Genetic Variants in METTL14 are Associated with the Risk of Acute Lymphoblastic Leukemia in Southern Chinese Children: A Five-Center Case-Control Study

Luo A, Yang L, Li M, Cai M, Huang A, Liu X, Yang X, Yan Y, Wang X, Wu X, Huang K, Huang L, Liu S, Xu L, Liu X

Cancer Management and Research 2021, 13:9189-9200

Published Date: 14 December 2021

LncRNA FENDRR Inhibits Gastric Cancer Cell Proliferation and Invasion via the miR-421/SIRT3/Notch-1 Axis

Ma J, Zhao G, Du J, Li J, Lin G, Zhang J

Cancer Management and Research 2021, 13:9175-9187

Published Date: 14 December 2021

Rationale and Design for a Multicenter, Phase II Study of Durvalumab Plus Concurrent Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer: The DOLPHIN Study (WJOG11619L)

Tachihara M, Tsujino K, Ishihara T, Hayashi H, Sato Y, Kurata T, Sugawara S, Okamoto I, Teraoka S, Azuma K, Daga H, Yamaguchi M, Kodaira T, Satouchi M, Shimokawa M, Yamamoto N, Nakagawa K

Cancer Management and Research 2021, 13:9167-9173

Published Date: 14 December 2021

PD-L1 Expression in Endometrial Serous Carcinoma and Its Prognostic Significance

Zhang T, Liu Q, Zhu Y, Zhang S, Peng Q, Strickland AL, Zheng W, Zhou F

Cancer Management and Research 2021, 13:9157-9165

Published Date: 14 December 2021

Review

Ketogenic Diets and their Therapeutic Potential on Breast Cancer: A Systemic Review

Jemal M, Molla TS, Asmamaw Dejenie T

Cancer Management and Research 2021, 13:9147-9155

Published Date: 14 December 2021

LncRNA HLA-F-AS1 Enhances the Migration, Invasion and Apoptosis of Glioblastoma Cells by Targeting lncRNA MEG3

Wang Y, Xie T, Liu H, Yu X

Cancer Management and Research 2021, 13:9139-9145

Published Date: 11 December 2021

Patterns of Care and Outcomes for Non-Metastatic Prostate Cancer in the United States: Results of the CancerMPact® Survey 2018

de Sá Moreira E, Robinson D, Hawthorne S, Zhao L, Hanson M, Kanas G, Turnure M, Davis C, Clark O

Cancer Management and Research 2021, 13:9127-9137

Published Date: 11 December 2021

Modified Frailty Index Independently Predicts Postoperative Pulmonary Infection in Elderly Patients Undergoing Radical Gastrectomy for Gastric Cancer

Meng Y, Zhao P, Yong R

Cancer Management and Research 2021, 13:9117-9126

Published Date: 11 December 2021

A National Chinese Survey on Ultrasound Feature Interpretation and Risk Assessment of Breast Masses Under ACR BI-RADS

Wen W, Liu J, Wang J, Jiang H, Peng Y

Cancer Management and Research 2021, 13:9107-9115

Published Date: 11 December 2021

miR-145-5p: A Potential Biomarker in Predicting Gleason Upgrading of Prostate Biopsy Samples Scored 3+3=6

Wang T, Dong L, Sun J, Shao J, Zhang J, Chen S, Wang C, Wu G, Wang X

Cancer Management and Research 2021, 13:9095-9106

Published Date: 10 December 2021

Efficacy of Chemotherapy versus Transcatheter Arterial Chemoembolization in Patients with Advanced Primary Hepatic Neuroendocrine Carcinoma and an Analysis of the Prognostic Factors: A Retrospective Study

Li S, Niu M, Deng W, Li N, Wei C, Zhang C, Luo S

Cancer Management and Research 2021, 13:9085-9093

Published Date: 10 December 2021

Efficacy and Safety of Epirubicin Combined with Temozolomide for Treatment of Advanced Leiomyosarcoma

Tan H, Zuo L, Ma S, Wang D, Li R, Yang Y, Liu W, Chi Y

Cancer Management and Research 2021, 13:9075-9083

Published Date: 10 December 2021

Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma [Retraction]

Fan J, Kang X, Zhao L, Zheng Y, Yang J, Li D

Cancer Management and Research 2021, 13:9073-9074

Published Date: 9 December 2021

Comparisons of Outcomes Between Adolescent and Young Adult with Older Patients After Radical Resection of Pancreatic Ductal Adenocarcinoma by Propensity Score Matching: A Single-Center Study

Tang N, Dou X, You X, Liu G, Ou Z, Zai H

Cancer Management and Research 2021, 13:9063-9072

Published Date: 8 December 2021

BBOX1-AS1 Accelerates Nasopharyngeal Carcinoma Progression by Sponging miR-3940-3p and Enhancing KPNA2 Upregulation

Jiang H, He Q, Liu T

Cancer Management and Research 2021, 13:9049-9062

Published Date: 8 December 2021

LncRNA FOXD3-AS1 Promotes Tumorigenesis of Glioma via Targeting miR-128-3p/SZRD1 Axis

Li Z, Li M, Xia P, Wang L, Lu Z

Cancer Management and Research 2021, 13:9037-9048

Published Date: 7 December 2021

miR-1306 Promotes Lung Squamous Cell Carcinoma Progression and Predicts Clinical Prognosis of Patients

Li M, Xu C, Wang Y, Liu H

Cancer Management and Research 2021, 13:9029-9035

Published Date: 7 December 2021

Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway [Retraction]

Malale K, Fu J, Qiu L, Zhan K, Gan X, Mei Z

Cancer Management and Research 2021, 13:9027-9028

Published Date: 7 December 2021

A Sensitive PCR-Based Method for Somatic Mutations Enrichment and Screening [Corrigendum]

Xiong Y, Tang H

Cancer Management and Research 2021, 13:9025-9026

Published Date: 7 December 2021

Low Density Lipoprotein Receptor (LDLR) and 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase (HMGCR) Expression are Associated with Platinum-Resistance and Prognosis in Ovarian Carcinoma Patients

Huang X, Wei X, Qiao S, Zhang X, Li R, Hu S, Mao H, Liu P

Cancer Management and Research 2021, 13:9015-9024

Published Date: 6 December 2021

Nano-Silver Medical Antibacterial Dressing Combined with High-Flow Oxygen Therapy Facilitates Ulcer Wound Healing of Superficial Malignant Tumors

Yu D, Yang DX, Li Y, Guan B, Ming Q, Li Y, Zhu YP, Chen LQ, Luo WX

Cancer Management and Research 2021, 13:9007-9013

Published Date: 6 December 2021

Clinical Experience with Apatinib and Camrelizumab in Advance Clear Cell Sarcoma: A Retrospective Study

Wang J, Gao S, Yang Y, Liu X, Zhang P, Dong S, Wang X, Yao W

Cancer Management and Research 2021, 13:8999-9005

Published Date: 3 December 2021

Current Insights into the Management of Late Chemotherapy Toxicities in Pediatric Osteosarcoma Patients

Hecker-Nolting S, Langer T, Blattmann C, Kager L, Bielack SS

Cancer Management and Research 2021, 13:8989-8998

Published Date: 1 December 2021

Original Research

Recurrent Laryngeal Nerve Injury Near the Nerve Entry Point in Total Endoscopic Thyroidectomy: A Retrospective Cohort Study

Liu N, Chen B, Li L, Zeng Q, Sheng L, Zhang B, Liang W, Lv B

Cancer Management and Research 2021, 13:8979-8987

Published Date: 1 December 2021

Supervised Learning Based Systemic Inflammatory Markers Enable Accurate Additional Surgery for pT1NxM0 Colorectal Cancer: A Comparative Analysis of Two Practical Prediction Models for Lymph Node Metastasis

Jin J, Zhou H, Sun S, Tian Z, Ren H, Feng J

Cancer Management and Research 2021, 13:8967-8977

Published Date: 1 December 2021

Towards a Stepped Care Model for Managing Fear of Cancer Recurrence or Progression in Cancer Survivors

Pradhan P, Sharpe L, Menzies RE

Cancer Management and Research 2021, 13:8953-8965

Published Date: 1 December 2021

Bioinformatics Analysis of Hub Genes and Potential Therapeutic Agents Associated with Gastric Cancer

Zhang S, Xiang X, Liu L, Yang H, Cen D, Tang G

Cancer Management and Research 2021, 13:8929-8951

Published Date: 30 November 2021

Is the Fixed Periodic Treatment Effective for the Tumor System without Complete Information?

Wang J, Zhang Y, Liu X, Liu H

Cancer Management and Research 2021, 13:8915-8928

Published Date: 30 November 2021

The Potential of Visceral Adipose Tissue in Distinguishing Clear Cell Renal Cell Carcinoma from Renal Angiomyolipoma with Minimal Fat

Liu J, Bao J, Zhang W, Li Q, Hou J, Wei X, Huang Y

Cancer Management and Research 2021, 13:8907-8914

Published Date: 30 November 2021

Cytopenias After CD19 Chimeric Antigen Receptor T-Cells (CAR-T) Therapy for Diffuse Large B-Cell Lymphomas or Transformed Follicular Lymphoma: A Single Institution Experience

Schaefer A, Huang Y, Kittai A, Maakaron JE, Saygin C, Brammer J, Penza S, Saad A, Jaglowski SM, William BM

Cancer Management and Research 2021, 13:8901-8906

Published Date: 30 November 2021

Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition

Wang W, Yang C, Deng H

Cancer Management and Research 2021, 13:8887-8900

Published Date: 30 November 2021

Development and Validation of a Novel Prognostic Model for Endometrial Cancer Based on Clinical Characteristics

Yu Z, Wei S, Zhang J, Shi R, An L, Feng D, Wang H

Cancer Management and Research 2021, 13:8879-8886

Published Date: 27 November 2021

Serum Untargeted UHPLC-HRMS-Based Lipidomics to Discover the Potential Biomarker of Colorectal Advanced Adenoma

Zhu Y, Wang L, Nong Y, Liang Y, Huang Z, Zhu P, Zhang Q

Cancer Management and Research 2021, 13:8865-8878

Published Date: 26 November 2021

Screening History in Vaginal Precancer and Cancer: A Retrospective Study of 2131 Cases in China

Zhang L, Wang Q, Zhang H, Xie Y, Sui L, Cong Q

Cancer Management and Research 2021, 13:8855-8863

Published Date: 26 November 2021

Vascular Thrombosis and Anti-PD-1 Therapy: A Series of Cases

Fu C, Wang G, Yang W

Cancer Management and Research 2021, 13:8849-8853

Published Date: 25 November 2021

A Case of Acute Myeloid Leukemia Harboring a Rare Three-Way Translocation t(5;7;7) Involving the PDGFRB Gene and Successfully Treated with Imatinib

Borogovac A, Sahu KK, Vishwanathan GK, Miron PM, Cerny J

Cancer Management and Research 2021, 13:8841-8847

Published Date: 25 November 2021

Surgery and Chemotherapy versus Chemotherapy Only in Older Persons with Primary Intestinal Diffuse Large B-Cell Lymphoma

Zhang L, Huang H, Wang Z, Fang X, Hong H, Chen Y, Li F, Yao Y, Chen Z, Pan F, Li X, Chen M, Gale RP, Liang Y, Lin T

Cancer Management and Research 2021, 13:8831-8839

Published Date: 25 November 2021

Heart Rate Variability is an Independent Predictor of Lymph Node Metastasis in Patients with Cervical Cancer

Wang J, Liu J, Gao L, Li G, Sun Y, Shi B

Cancer Management and Research 2021, 13:8821-8830

Published Date: 24 November 2021

Metabolic Syndrome-Related Hyperuricemia is Associated with a Poorer Prognosis in Patients with Colorectal Cancer: A Multicenter Retrospective Study

Feng Q, Tang LJ, Luo DH, Wang Y, Wu N, Chen H, Chen MX, Jiang L, Jin R

Cancer Management and Research 2021, 13:8809-8819

Published Date: 24 November 2021

Activity of Melatonin Against Gastric Cancer Growth in a Chick Embryo Tumor Xenograft Model

Wang R, Liu H, Song J, Wu Q

Cancer Management and Research 2021, 13:8803-8808

Published Date: 24 November 2021

Demographics, Changes in Treatment Patterns, and Outcomes of Bone and Soft Tissue Sarcomas in Korea—A Sarcoma-Specific, Institutional Registry-Based Analysis

Jeong H, Im HS, Kim W, Lee JS, Song SY, Song JS, Cho KJ, Chung HW, Lee MH, Kim JE, Ahn JH

Cancer Management and Research 2021, 13:8795-8802

Published Date: 24 November 2021

Involvement of Non-Coding RNAs in Chemo- and Radioresistance of Nasopharyngeal Carcinoma

Xiao J, He X

Cancer Management and Research 2021, 13:8781-8794

Published Date: 23 November 2021

Predictive Value of Pretreatment Lymphocyte-to-Monocyte Ratio and Platelet-to-Lymphocyte Ratio in the Survival of Nasopharyngeal Carcinoma Patients

Chen Y, Sun J, Hu D, Zhang J, Xu Y, Feng H, Chen Z, Luo Y, Lou Y, Wu H

Cancer Management and Research 2021, 13:8767-8779

Published Date: 23 November 2021

Clinical and Prognostic Implications of 1p/19q, IDH, BRAF, MGMT Promoter, and TERT Promoter Alterations, and Expression of Ki-67 and p53 in Human Gliomas

Yang Z, Ling F, Ruan S, Hu J, Tang M, Sun X, Long W

Cancer Management and Research 2021, 13:8755-8765

Published Date: 23 November 2021

Original Research

Pathum Raksa Project: Addressing Disparity in Breast Cancer Care Through National Innovation in Thailand

Koonmee S, Somintara O, Intarawichian P, Aphivatanasiri C, Sangkhamanon S, Laohawiriyakamol S, Panawattanakul R, Mahantassanapong P, Rattadilok C, Jeeravongpanich P, Krongyute W, Prachumrasee K, Alaghehbandan R

Cancer Management and Research 2021, 13:8737-8753

Published Date: 23 November 2021

Original Research

Application of Machine Learning Techniques to Predict Bone Metastasis in Patients with Prostate Cancer

Liu WC, Li MX, Qian WX, Luo ZW, Liao WJ, Liu ZL, Liu JM

Cancer Management and Research 2021, 13:8723-8736

Published Date: 23 November 2021

Integrated Analysis of the m6A-Related lncRNA Identified lncRNA ABALON/miR-139-3p/NOB1 Axis Was Involved in the Occurrence of Lung Cancer

Liu X, Zuo X, Ma L, Wang Q, Zhu L, Li L, Zhao X

Cancer Management and Research 2021, 13:8707-8722

Published Date: 23 November 2021

A Prospective Observational Study of Osimertinib for Chemo-Naive Elderly Patients with EGFR Mutation-Positive Non-Small Cell Lung Cancer

Igawa S, Kasajima M, Ono T, Ozawa T, Kakegawa M, Kusuhara S, Sato T, Nakahara Y, Fukui T, Yokoba M, Kubota M, Mitsufuji H, Sasaki J, Naoki K

Cancer Management and Research 2021, 13:8695-8705

Published Date: 20 November 2021

lncRNA MCF2L-AS1/miR-105/ IL-1β Axis Regulates Colorectal Cancer Cell Oxaliplatin Resistance

Cai M, Hu W, Huang C, Zhou C, Li J, Chen Y, Yu Y

Cancer Management and Research 2021, 13:8685-8694

Published Date: 19 November 2021

Surgical Treatment of Postoperative Abdominal Metastases of Hepatocellular Carcinoma: 10-Year Experience in a Single Center

Fang J, Yang Y, Zhu HD, Sun JN, Mi HC, Lu CD

Cancer Management and Research 2021, 13:8673-8683

Published Date: 20 November 2021

Gut Microbiota and Sunitinib-Induced Diarrhea in Metastatic Renal Cell Carcinoma: A Pilot Study

Su Z, Lu L, Chen F, Chen J, Chen X

Cancer Management and Research 2021, 13:8663-8672

Published Date: 20 November 2021

Predictive Risk Factors for Early Recurrence of Stage pIIIA-N2 Non-Small Cell Lung Cancer

Yu Q, Du X, Fang Z, Mao X, Wu J, Wang B, Li W

Cancer Management and Research 2021, 13:8651-8661

Published Date: 18 November 2021

Disulfiram Inhibits Epithelial–Mesenchymal Transition Through TGFβ–ERK–Snail Pathway Independently of Smad4 to Decrease Oral Squamous Cell Carcinoma Metastasis [Corrigendum]

Bu W, Wang Z, Meng L, Li X, Liu X, Chen Y, Xin Y, Li B, Sun H

Cancer Management and Research 2021, 13:8647-8650

Published Date: 25 November 2021

Identification of Three Potential Prognostic Genes in Platinum-Resistant Ovarian Cancer via Integrated Bioinformatics Analysis

Zhang X, Wei X, Bai G, Huang X, Hu S, Mao H, Liu P

Cancer Management and Research 2021, 13:8629-8646

Published Date: 16 November 2021

Identification of Prognostic Biomarkers Among FAM83 Family Genes in Human Ovarian Cancer Through Bioinformatic Analysis and Experimental Verification

Lin S, Du J, Hao J, Luo X, Wu H, Zhang H, Zhao X, Xu L, Wang B

Cancer Management and Research 2021, 13:8611-8627

Published Date: 15 November 2021

Targeting Oncogenic miR-181a-2-3p Inhibits Growth and Suppresses Cisplatin Resistance of Gastric Cancer

Jin L, Ma X, Zhang N, Zhang Q, Chen X, Zhang Z, Ding G, Yu H

Cancer Management and Research 2021, 13:8599-8609

Published Date: 16 November 2021

Prognostic Significance of Preoperative Prognostic Nutritional Index for Overall Survival and Postoperative Complications in Esophageal Cancer Patients

Qi Q, Song Q, Cheng Y, Wang N

Cancer Management and Research 2021, 13:8585-8597

Published Date: 16 November 2021

LncRNA DNAJC3-AS1 Promotes Hepatocellular Carcinoma (HCC) Progression via Sponging Premature miR-27b

Fu C, Li J, Li P, Cheng D

Cancer Management and Research 2021, 13:8575-8583

Published Date: 15 November 2021

LINC00261 Inhibits Esophageal Cancer Radioresistance by Down-Regulating microRNA-552-3p and Promoting DIRAS1

Yang B, Ma H, Bian Y

Cancer Management and Research 2021, 13:8559-8573

Published Date: 13 November 2021

LncRNA GATA6-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer via Repressing microRNA-543 to Up-Regulating RKIP [Expression of Concern]

Gong Z, Chen X, Zhang Y, Liu C, Wang Z, Xu X, Zhu J, Xue T

Cancer Management and Research 2021, 13:8557-8558

Published Date: 15 November 2021

MicroRNA-365 Targets Multiple Oncogenes to Inhibit Proliferation, Invasion, and Self-Renewal of Aggressive Endometrial Cancer Cells [Retraction]

Wang C, Su K, Zhang Y, Zhang W, Chu D, Zhao Q, Guo R

Cancer Management and Research 2021, 13:8555-8556

Published Date: 15 November 2021

Hsa_circ_0015326 Promotes the Proliferation, Invasion and Migration of Ovarian Cancer Through miR-127-3p/MYB [Retraction]

Zhang C, Liu W, Li F, Feng Y, Li Y, Wang J

Cancer Management and Research 2021, 13:8553-8554

Published Date: 15 November 2021

A Cytoplasm-Enriched circRNA circ-MYBL2 is Downregulated in Non-Small Cell Lung Cancer and Sponges Oncogenic miR-28 to Regulate Cancer Cell Proliferation and Apoptosis [Retraction]

Mao Y, Wang C

Cancer Management and Research 2021, 13:8551-8552

Published Date: 15 November 2021

AGTR1 Inhibits the Progression of Lung Adenocarcinoma

Xiong L, Wei Y, Zhou X, Dai P, Cai Y, Zhou X, Xu M, Zhao J, Tang H

Cancer Management and Research 2021, 13:8535-8550

Published Date: 13 November 2021

Clinicopathological Features and Prognosis of Primary Mediastinal Malignant Germ Cell Tumors: A Retrospective Single-Institution Analysis

Zhang J, Chen Y, Liu L, Zhou M, Huang C, Guo C, Li S

Cancer Management and Research 2021, 13:8527-8534

Published Date: 13 November 2021

Sp1 Contributes to Radioresistance of Cervical Cancer Through Targeting G2/M Cell Cycle Checkpoint CDK1 [Corrigendum]

Deng YR, Chen XJ, Chen W, Wu LF, Jiang HP, Lin D, Wang LJ, Wang W, Guo SQ

Cancer Management and Research 2021, 13:8525-8526

Published Date: 15 November 2021

Dl-3-N-Butylphthalide Presents Anti-Cancer Activity in Lung Cancer by Targeting PD-1/PD-L1 Signaling

Jiang Q, Zhang N, Li X, Hou W, Zhao XQ, Liu L

Cancer Management and Research 2021, 13:8513-8524

Published Date: 12 November 2021

Development and Validation of a Nomogram Model to Predict Acute Kidney Disease After Nephrectomy in Patients with Renal Cell Carcinoma [Erratum]

Hu XY, Liu DW, Qiao YJ, Zheng X, Duan JY, Pan SK, Liu ZS

Cancer Management and Research 2021, 13:8511-8512

Published Date: 12 November 2021

Prognostic Value of Preoperative Mean Platelet Volume and a Predictive Nomogram in Oral Squamous Cell Carcinoma Patients Based on Real-World Data

Ning Y, Yang H, Qin S, Cao B, Zhong Z, He C, Zhu G

Cancer Management and Research 2021, 13:8495-8509

Published Date: 10 November 2021

Phase II Study of Nivolumab Plus Ipilimumab with Platinum-Based Chemotherapy for Treatment-Naïve Advanced Non-Small Cell Lung Cancer with Untreated Brain Metastases: NIke Trial (LOGiK2004)

Tsuchiya-Kawano Y, Shiraishi Y, Kiyomi F, Okamoto I

Cancer Management and Research 2021, 13:8489-8493

Published Date: 11 November 2021

Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study

Wang J, Dong S, Zhang J, Gao S, Li Z, Li P, Yuan J, Tian Z

Cancer Management and Research 2021, 13:8481-8487

Published Date: 10 November 2021

Clinical Outcome in Soft Tissue Sarcoma Patients with Lung Metastasis Who Received Metastasectomy and/or Radiofrequency Ablation: Tokai Musculoskeletal Oncology Consortium Study

Nakamura T, Asanuma K, Takao M, Yamanaka T, Koike H, Chen-Yoshikawa TF, Tsukushi S, Kuroda H, Kozawa E, Sano M, Aiba H, Nakanishi R, Nagano A, Yamada K, Shido Y, Kawanami K, Izubuchi Y, Sudo A, Nishida Y

Cancer Management and Research 2021, 13:8473-8480

Published Date: 10 November 2021

Perspectives

The Impasse on Overall Survival in Oncology Reimbursement Decision-Making: How Can We Resolve This?

Lux MP, Ciani O, Dunlop WCN, Ferris A, Friedlander M

Cancer Management and Research 2021, 13:8457-8471

Published Date: 10 November 2021

Knockdown of hsa_circ_0000729 Inhibits the Tumorigenesis of Non-Small Cell Lung Cancer Through Mediation of miR-1281/FOXO3 Axis

Xie X, Ding F, Xiao H

Cancer Management and Research 2021, 13:8445-8455

Published Date: 10 November 2021

A Novel Circular RNA circPTCD3 Promotes Breast Cancer Progression Through Sponging miR-198

Zhang Z, Hu H, Li Q, Yi F, Liu Y

Cancer Management and Research 2021, 13:8435-8443

Published Date: 10 November 2021

Microribonucleic Acid-15a-5p Alters Adriamycin Resistance in Breast Cancer Cells by Targeting Cell Division Cycle-Associated Protein 4

Zhang JT, Chen J, Ruan HC, Li FX, Pang S, Xu YJ, Huang DL, Wu XH

Cancer Management and Research 2021, 13:8425-8434

Published Date: 10 November 2021

A Novel Predictive Model Associated with Osteosarcoma Metastasis

Zhang H, Chen G, Lyu X, Rong C, Wang Y, Xu Y, Lyu C

Cancer Management and Research 2021, 13:8411-8423

Published Date: 9 November 2021

Comparison of Minimally Invasive Tubular Surgery with Conventional Surgery in the Treatment of Thoracolumbar Metastasis

Cui Y, Shi X, Mi C, Wang B, Pan Y, Lin Y

Cancer Management and Research 2021, 13:8399-8409

Published Date: 9 November 2021

Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis

Wang Z, Yan H, Cheng D, Xu L, Shen T, Chen Y, Han R, Xue Y

Cancer Management and Research 2021, 13:8387-8397

Published Date: 9 November 2021

Clinical Impact of Cachexia in Head and Neck Cancer Patients Who Received Chemoradiotherapy

Hayashi N, Sato Y, Fujiwara Y, Fukuda N, Wang X, Nakano K, Urasaki T, Ohmoto A, Ono M, Tomomatsu J, Sato Y, Mitani H, Toshiyasu T, Takahashi S

Cancer Management and Research 2021, 13:8377-8385

Published Date: 8 November 2021

Prognostic Value of lncRNA DRAIC and miR-3940-3p in Lung Adenocarcinoma and Their Effect on Lung Adenocarcinoma Cell Progression

Liu Z, Yang S, Zhou S, Dong S, Du J

Cancer Management and Research 2021, 13:8367-8376

Published Date: 5 November 2021

Circulating Tumor Cells in Esophageal Squamous Cell Carcinoma – Mini Review

Shi Y, Ge X, Ju M, Zhang Y, Di X, Liang L

Cancer Management and Research 2021, 13:8355-8365

Published Date: 5 November 2021

Suppressing Growth and Invasion of Human Hepatocellular Carcinoma Cells by Celecoxib Through Inhibition of Cyclooxygenase-2 [Corrigendum]

Tai Y, Zhang LH, Gao JH, Zhao C, Tong H, Ye C, Huang ZY, Liu R, Tang CW

Cancer Management and Research 2021, 13:8353-8354

Published Date: 8 November 2021

Development and Evaluation of Serum CST1 Detection for Early Diagnosis of Esophageal Squamous Cell Carcinoma

Wang J, Yu L, Sun Y, Zhang L, Tu M, Cai L, Yin X, Pan X, Wang T, Huang Y

Cancer Management and Research 2021, 13:8341-8352

Published Date: 5 November 2021

Exosomal miR-122-5p is Related to the Degree of Myelosuppression Caused by Chemotherapy in Patients with Colorectal Cancer

Chen J, Wu W, He X, Jia L, Yang J, Si X, Yu K, Li S, Qiu Y, Xu K, Yin P, Cao Y, Li Q, Li W

Cancer Management and Research 2021, 13:8329-8339

Published Date: 3 November 2021

Advances in the Prediction and Risk Assessment of Lung Cancer-Associated Venous Thromboembolism

Di W, Xu H, Xue T, Ling C

Cancer Management and Research 2021, 13:8317-8327

Published Date: 4 November 2021

A Comparison of Different Schemes of Neoadjuvant Chemotherapy Followed by Concurrent Chemotherapy and Radiotherapy for Locally Advanced Cervical Cancer: A Retrospective Study

Tian X, Yang F, Li F, Ran L, Chang J, Li J, Hong W, Shan L, Du Y, Hu L, Mei F, He M, Li Y, Wang H, Zuo K, Zhou B, Chen S, Mao W

Cancer Management and Research 2021, 13:8307-8316

Published Date: 3 November 2021

Cost-Effectiveness Analysis of Gefitinib Plus Chemotherapy versus Gefitinib Alone for Advanced Non-Small-Cell Lung Cancer with EGFR Mutations in China

Shu Y, Zhang Q, He X, Chen L

Cancer Management and Research 2021, 13:8297-8306

Published Date: 3 November 2021

Review

Gut Microbiota: A Potential Target for Cancer Interventions

Zhou H, Yuan Y, Wang H, Xiang W, Li S, Zheng H, Wen Y, Ming Y, Chen L, Zhou J

Cancer Management and Research 2021, 13:8281-8296

Published Date: 3 November 2021

Efficacy and Safety of Interferon-Alpha 2b for Patients with Hepatic Epithelioid Hemangioendothelioma: Outcomes of a Case-Series Analysis

Liu X, Zhang Z, Huang J, Tan H, Yang Z

Cancer Management and Research 2021, 13:8273-8279

Published Date: 3 November 2021

Circulating miRNAs as Potential Biomarkers in Prostate Cancer Patients Undergoing Radiotherapy

Kachris S, Papadaki C, Rounis K, Tsitoura E, Kokkinaki C, Nikolaou C, Sourvinos G, Mavroudis D

Cancer Management and Research 2021, 13:8257-8271

Published Date: 2 November 2021

Dynamics of Early Serum Tumour Markers and Neutrophil-to-Lymphocyte Ratio Predict Response to PD-1/PD-L1 Inhibitors in Advanced Non-Small-Cell Lung Cancer

Tang Y, Cui Y, Li L, Guan Y, Feng D, Yin B, Liang X, Yin J, Jiang R, Liang J, Sun Y, Wang J

Cancer Management and Research 2021, 13:8241-8255

Published Date: 2 November 2021

The Role and Mechanism of Autophagy in Pancreatic Cancer: An Update Review

Ma J, Xue H, He LH, Wang LY, Wang XJ, Li X, Zhang L

Cancer Management and Research 2021, 13:8231-8240

Published Date: 2 November 2021

Cost-Effectiveness Analysis of Camrelizumab Immunotherapy versus Docetaxel or Irinotecan Chemotherapy as Second-Line Therapy for Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Lin YT, Chen Y, Liu TX, Kuang F, Huang P

Cancer Management and Research 2021, 13:8219-8230

Published Date: 2 November 2021

Automatic Segmentation of Clinical Target Volume and Organs-at-Risk for Breast Conservative Radiotherapy Using a Convolutional Neural Network

Liu Z, Liu F, Chen W, Tao Y, Liu X, Zhang F, Shen J, Guan H, Zhen H, Wang S, Chen Q, Chen Y, Hou X

Cancer Management and Research 2021, 13:8209-8217

Published Date: 2 November 2021

Checkpoint Inhibitors in Melanoma Patients with Underlying Autoimmune Disease

Dietz H, Weinmann SC, Salama AK

Cancer Management and Research 2021, 13:8199-8208

Published Date: 2 November 2021

Original Research

Characterization of Treatments and Disease Course for Women with Breast Cancer Brain Metastases: 5-Year Retrospective Single Institution Experience

Chew S, Carroll HK, Darwish W, Boychak O, Higgins M, McCaffrey J, Kelly CM

Cancer Management and Research 2021, 13:8191-8198

Published Date: 2 November 2021

Matching-Adjusted Indirect Comparison of Ribociclib Plus Fulvestrant versus Palbociclib Plus Letrozole as First-Line Treatment of HR+/HER2− Advanced Breast Cancer

Fasching PA, Delea TE, Lu YS, De Boer R, Hurvitz SA, Moynahan A, Chandiwana D, Lanoue B, Hu H, Thuerigen A, O'Shaughnessy J

Cancer Management and Research 2021, 13:8179-8189

Published Date: 1 November 2021

Survival Effects of Radiotherapy on Patients Newly Diagnosed with Distant Metastatic Nasopharyngeal Carcinoma in Non-High-Incidence Areas

Yang Y, Li X, Zhou P, Deng X, Wang Y, Dang Q, Zheng Y, Yang D

Cancer Management and Research 2021, 13:8169-8178

Published Date: 2 November 2021

A Radiomics Nomogram for Preoperative Prediction of Clinical Occult Lymph Node Metastasis in cT1-2N0M0 Solid Lung Adenocarcinoma

Zhang R, Zhang R, Luan T, Liu B, Zhang Y, Xu Y, Sun X, Xing L

Cancer Management and Research 2021, 13:8157-8167

Published Date: 28 October 2021

LINC00265/miR-4500 Axis Accelerates Acute Lymphoblastic Leukemia Progression by Enhancing STAT3 Signals

Zhao D, Xing Q, Song H, Zhao Y, Guo G

Cancer Management and Research 2021, 13:8147-8156

Published Date: 28 October 2021

Prognostic Value of Lymph Node Characteristics in Patients with Cervical Cancer Treated with Radical Hysterectomy

Lee YH, Chong GO, Kim SJ, Hwang JH, Kim JM, Park NJY, Hong DG

Cancer Management and Research 2021, 13:8137-8145

Published Date: 28 October 2021

Prognosis of Early Stage Cervical Cancer According to Patterns of Recurrence

Chen Y, Zhu Y, Wu J

Cancer Management and Research 2021, 13:8131-8136

Published Date: 28 October 2021

Exosomes and Exosomal circRNAs: The Rising Stars in the Progression, Diagnosis and Prognosis of Gastric Cancer

Lu L, Fang S, Zhang Y, Jin L, Xu W, Liang Z

Cancer Management and Research 2021, 13:8121-8129

Published Date: 27 October 2021

Prognostic Significance of Circulating Lymphocyte Subsets Before Treatment in Patients with Nasopharyngeal Carcinoma

Shen DS, Yan C, Liang Y, Chen KH, Zhu XD

Cancer Management and Research 2021, 13:8109-8120

Published Date: 27 October 2021

A Sensitive PCR-Based Method for Somatic Mutations Enrichment and Screening

Xiong Y, Tang H

Cancer Management and Research 2021, 13:8099-8107

Published Date: 27 October 2021

Review

Optimal Management of Patients with Advanced or Metastatic Cholangiocarcinoma: An Evidence-Based Review

Ioffe D, Phull P, Dotan E

Cancer Management and Research 2021, 13:8085-8098

Published Date: 27 October 2021

Analysis of the Effect of Trastuzumab Combined with Docetaxel on Serum Tumor Markers in the Treatment of HER-2 Positive Breast Cancer and Factors Influencing Therapeutic Efficacy

Feng QZ, Chen XZ, Sun J, Lu MM, Wang Y, Wang Q, Zhang C

Cancer Management and Research 2021, 13:8077-8084

Published Date: 27 October 2021

Targeted Inhibition of HK-II Reversed the Warburg Effect to Improve the Radiosensitivity of Laryngeal Carcinoma

Chen XH, Yu DL, Zhong JT, Zhou SH, Fan J, Lu ZJ

Cancer Management and Research 2021, 13:8063-8076

Published Date: 27 October 2021

The Hsa_circ_0091579/miR-940/TACR1 Axis Regulates the Development of Hepatocellular Carcinoma [Retraction]

Jiang P, Han W, Fu Y, Chen Q

Cancer Management and Research 2021, 13:8061-8062

Published Date: 26 October 2021

Silenced Myeloblastosis Protein Suppresses Oral Tongue Squamous Cell Carcinoma via the microRNA-130a/Cylindromatosis Axis [Retraction]

Yang R, Shui Y, Hu S, Zhang K, Wang Y, Peng Y

Cancer Management and Research 2021, 13:8059-8060

Published Date: 26 October 2021

Circular RNA CircCDYL Regulates Proliferation and Apoptosis in Non-Small Cell Lung Cancer Cells by Sponging miR-185-5p and Upregulating TNRC6A [Expression of Concern]

Bian WX, Xue F, Wang LY, Xing XF

Cancer Management and Research 2021, 13:8057-8058

Published Date: 26 October 2021

The Association of Clinical Outcomes with Posttreatment Changes in the Relative Eosinophil Counts and Neutrophil-to-Eosinophil Ratio in Patients with Advanced Urothelial Carcinoma Treated with Pembrolizumab

Furubayashi N, Minato A, Negishi T, Sakamoto N, Song Y, Hori Y, Tomoda T, Tamura S, Kuroiwa K, Seki N, Fujimoto N, Nakamura M

Cancer Management and Research 2021, 13:8049-8056

Published Date: 24 October 2021

Optimal Lymph Node Yield for Survival Prediction in Rectal Cancer Patients After Neoadjuvant Therapy

Lin YM, Chou CL, Kuo YH, Wu HC, Tsai CJ, Ho CH, Chen YC, Yang CC, Lin CW

Cancer Management and Research 2021, 13:8037-8047

Published Date: 24 October 2021

miRNA-382-5p Suppresses the Expression of Farnesoid X Receptor to Promote Progression of Liver Cancer

Nie X, Liu H, Wei X, Li L, Lan L, Fan L, Ma H, Liu L, Zhou Y, Hou R, Chen WD

Cancer Management and Research 2021, 13:8025-8035

Published Date: 22 October 2021

Radiation Therapy Efficacy and Toxicity for Orbital and Ocular Adnexal Mucosa-Associated Lymphoid Tissue (OAMALT): A Single-Center, Retrospective Study of 32 Cases

Xu L, Tang X, Jiang N, Zhang S, Cao Y, Sun X

Cancer Management and Research 2021, 13:8017-8024

Published Date: 21 October 2021

Case report

Synchronous Rectal Tumours with Different Molecular and Genetic Phenotypes Occurring in a Patient with Lynch Syndrome

Gou Q, Xie Y, Zhang M, Chen Y, Shen Y

Cancer Management and Research 2021, 13:8009-8015

Published Date: 21 October 2021

Long Noncoding RNA LINC00839 Promotes the Malignant Progression of Osteosarcoma by Competitively Binding to MicroRNA-454-3p and Consequently Increasing c-Met Expression [Retraction]

Zhang Y, Guo H, Ma L, Chen X, Chen G

Cancer Management and Research 2021, 13:8007-8008

Published Date: 21 October 2021

Downregulation of MicroRNA-130a Inhibits Oral Squamous Cell Carcinoma Proliferation and Metastasis via the Hippo-YAP Pathway [Retraction]

Peng Y, Hu S, Zhang K, Wang Y, Rouzi M, Zhou D, Yang R

Cancer Management and Research 2021, 13:8005-8006

Published Date: 21 October 2021

LncRNA PTCSC3 and lncRNA HULC Negatively Affect Each Other to Regulate Cancer Cell Invasion and Migration in Gastric Cancer [Retraction]

Cai Y, Li Y, Sun B, Wang H, Zhang W, Zhao Y, Zhao H, Zhang J, Xu J, Wang Y

Cancer Management and Research 2021, 13:8003-8004

Published Date: 21 October 2021

Comprehensive Analysis of the Prognostic Value and Immune Infiltrates of the Three-m5C Signature in Colon Carcinoma

Geng Q, Wei Q, Shen Z, Zheng Y, Wang L, Xue W, Li L, Zhao J

Cancer Management and Research 2021, 13:7989-8002

Published Date: 20 October 2021

Hepatic Hilar Lymph Node Resection in Cytoreductive Surgery for Advanced Ovarian Cancer: A Necessity or Not?

Huang H, Wei R, Long Y, Mo Y, Xie Y, Yao D

Cancer Management and Research 2021, 13:7981-7988

Published Date: 20 October 2021

Initial Experience of Drug-Eluting Bead-Transcatheter Arterial Chemoembolization After Lipiodol-Based Transcatheter Arterial Chemoembolization Failure for Patients with Advanced Hepatocellular Carcinoma

Liu KC, lv WF, Lu D, Hou CL, Xie J, Lu YH, Cao QS, Tan YL, Zhang YZ, Liu J

Cancer Management and Research 2021, 13:7973-7980

Published Date: 19 October 2021

Long Noncoding RNA VPS9D1-AS1 Sequesters microRNA-525-5p to Promote the Oncogenicity of Colorectal Cancer Cells by Upregulating HMGA1 [Expression of Concern]

Liu H, Zhang X, Jin X, Yang Y, Liang G, Ma Y, Wang B

Cancer Management and Research 2021, 13:7971-7972

Published Date: 20 October 2021

Long Noncoding RNA KCNMB2-AS1 Increases ROCK1 Expression by Sponging microRNA-374a-3p to Facilitate the Progression of Non–Small-Cell Lung Cancer [Expression of Concern]

Yang H, Wang Z, Wang Z

Cancer Management and Research 2021, 13:7969-7970

Published Date: 20 October 2021

Long Noncoding RNA PRR34-AS1 Aggravates the Progression of Hepatocellular Carcinoma by Adsorbing microRNA-498 and Thereby Upregulating FOXO3 [Expression of Concern]

Liu Z, Li Z, Xu B, Yao H, Qi S, Tai J

Cancer Management and Research 2021, 13:7967-7968

Published Date: 20 October 2021

Long Non-Coding RNA LINC00466 Knockdown Inhibits Tongue Squamous Cell Carcinoma Malignancy by Targeting microRNA-493/HMGA2 [Expression of Concern]

Hou C, Dong Y, Du B

Cancer Management and Research 2021, 13:7965-7966

Published Date: 20 October 2021

Long Noncoding RNA LINC01426 Sequesters microRNA-519d-5p to Promote Non-Small Cell Lung Cancer Progression by Increasing ETS1 Expression [Expression of Concern]

Dai J, Wang B, Zhao Y, Zuo X, Cui H, Chen X, Liu X

Cancer Management and Research 2021, 13:7963-7964

Published Date: 20 October 2021

LINC00504 Promotes the Malignant Biological Behavior of Breast Cancer Cells by Upregulating HMGB3 via Decoying MicroRNA-876-3p [Expression of Concern]

Yu H, Dong L, Wang H, Zhang Y, Wang Z, Wang C, Xia H, Bao H

Cancer Management and Research 2021, 13:7961-7962

Published Date: 20 October 2021

Predicting T and N Staging of Resectable Gastric Cancer According to Whole Tumor Histogram Analysis About a Non-Cartesian k-Space Acquisition DCE-MRI: A Feasibility Study

Yan L, Qu J, Li J, Zhang H, Lu Y, Gao J

Cancer Management and Research 2021, 13:7951-7960

Published Date: 18 October 2021

Correlation of Metabolic Factors with Endometrial Atypical Hyperplasia and Endometrial Cancer: Development and Assessment of a New Predictive Nomogram

Zhang H, Kong W, Han C, Liu T, Li J, Song D

Cancer Management and Research 2021, 13:7937-7949

Published Date: 18 October 2021

Case report

Pathology Behind Constant Watery Vaginal Discharge: A Rare Case of Uterine Cervical Minimal Deviation Adenocarcinoma

Xie Y, Zhou Q, Chen L, Sui L

Cancer Management and Research 2021, 13:7929-7935

Published Date: 19 October 2021

The Association Between PNPLA2 Methylation in Peripheral Blood and Early-Stage Lung Cancer in a Case–Control Study

Qiao R, Li M, Zhong R, Wei Y, Wang J, Zhang Z, Wang L, Xu T, Wang Y, Dai L, Gu W, Han B, Yang R

Cancer Management and Research 2021, 13:7919-7927

Published Date: 15 October 2021

The Biological Synthesis and the Function of Mucin 2 in Pseudomyxoma Peritonei

Lin YL, Li Y

Cancer Management and Research 2021, 13:7909-7917

Published Date: 15 October 2021

Silencing of LncRNA AFAP1-AS1 Inhibits Cell Proliferation in Oral Squamous Cancer by Suppressing CCNA2

Li T, Liu D, Li C, Ru L, Wang X

Cancer Management and Research 2021, 13:7897-7908

Published Date: 15 October 2021

A Narrative Review of Ultrasound Technologies for the Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer

Wang J, Chu Y, Wang B, Jiang T

Cancer Management and Research 2021, 13:7885-7895

Published Date: 14 October 2021

Characterisation of Levonorgestrel-Resistant Endometrial Cancer Cells

Dore M, Filoche S, Danielson K, Henry C

Cancer Management and Research 2021, 13:7871-7884

Published Date: 14 October 2021

Circular RNA Circ-0003006 Promotes Hepatocellular Carcinoma Proliferation and Metastasis Through Sponging miR-542-3p and Regulating HIF-1A

Tu Q, You X, He J, Hu X, Xie C, Xu G

Cancer Management and Research 2021, 13:7859-7870

Published Date: 13 October 2021

High Expression of PKM2 Was Associated with the Poor Prognosis of Acute Leukemia

Huang Y, Chen L, Xie J, Han H, Zhu B, Wang L, Wang W

Cancer Management and Research 2021, 13:7851-7858

Published Date: 13 October 2021

MiR-10a-5p: A Promising Biomarker for Early Diagnosis and Prognosis Evaluation of Bladder Cancer

Yang L, Sun HF, Guo LQ, Cao HB

Cancer Management and Research 2021, 13:7841-7850

Published Date: 14 October 2021

Organ-Sparing Strategies in Muscle-Invasive Bladder Cancer

Witjes JA, Feikema AAH

Cancer Management and Research 2021, 13:7833-7839

Published Date: 13 October 2021

Simple Hysterectomy for Patients with Stage IA2 Cervical Cancer: A Retrospective Cohort Study

Liu Q, Xu Y, He Y, Du Y, Zhang Q, Jia Y, Zheng A

Cancer Management and Research 2021, 13:7823-7832

Published Date: 13 October 2021

Evaluation of HRCT for the Differential Diagnosis of Pneumonia-Like Consolidation Pattern of Pulmonary MALT Lymphoma from Lobar Pneumonia

Qiu W, Chen H, Zhang J, Shuai R, Zhang H, Guo K, Zhu L, Wang Z

Cancer Management and Research 2021, 13:7813-7821

Published Date: 12 October 2021

Knockdown of LINC01224 Suppresses Colon Cancer Progression by Sponging miR-485-5p to Downregulate MCL1

Yuan D, Zhu Y

Cancer Management and Research 2021, 13:7803-7812

Published Date: 12 October 2021

The Prognostic Significance of Preoperative Platelet-to-Lymphocyte and Neutrophil-to-Lymphocyte Ratios in Patients Operated for Non-Small Cell Lung Cancer

Łochowski M, Chałubińska-Fendler J, Zawadzka I, Łochowska B, Rębowski M, Brzeziński D, Kozak J

Cancer Management and Research 2021, 13:7795-7802

Published Date: 9 October 2021

A Practical Predictive Model Based on Ultrasound Imaging and Clinical Indices for Estimation of Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer

Ye P, Duan H, Zhao Z, Fang S

Cancer Management and Research 2021, 13:7783-7793

Published Date: 9 October 2021

A Survival Prediction Nomogram for Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Chemoradiotherapy Followed by Surgery

Ding T, Liu C, Huang B, Chu L, Wei L, Lin Y, Luo Y, Zhang B, Hong C, Xu Y, Peng Y

Cancer Management and Research 2021, 13:7771-7782

Published Date: 9 October 2021

Clinical Value of Combined Detection of Serum sTim-3 and Pepsinogen for Gastric Cancer Diagnosis

Chen L, Hong J, Hu R, Yu X, Chen X, Zheng S, Qin Y, Zhou X, Wang Y, Zheng L, Fang H, Liu P, Huang B

Cancer Management and Research 2021, 13:7759-7769

Published Date: 9 October 2021

Review

The Evolving Role of FGFR2 Inhibitors in Intrahepatic Cholangiocarcinoma: From Molecular Biology to Clinical Targeting

Salati M, Caputo F, Baldessari C, Carotenuto P, Messina M, Caramaschi S, Dominici M, Bonetti LR

Cancer Management and Research 2021, 13:7747-7757

Published Date: 9 October 2021

Predicting Malignancy of Biliary Stricture with a Nomogram in Patients with a Non-Malignant Endoscopic Tissue Diagnosis: A Retrospective Study

Zhang Y, Jiang Q, Wang Q, Feng Y, Wu D, Guo T, Zhang S, Chen X, Yang Y, Shi W, Wu X, Yang A

Cancer Management and Research 2021, 13:7735-7745

Published Date: 11 October 2021

Perioperative Use of Glucocorticoids and Intraoperative Hypotension May Affect the Incidence of Postoperative Infection in Patients with Gastric Cancer: A Retrospective Cohort Study

Zhang Y, Li S, Yan C, Chen J, Shan F

Cancer Management and Research 2021, 13:7723-7734

Published Date: 8 October 2021

Development and Validation of a Prognostic Model of RNA-Binding Proteins in Colon Adenocarcinoma: A Study Based on TCGA and GEO Databases

Zhu D, Chen J, Hou T

Cancer Management and Research 2021, 13:7709-7722

Published Date: 8 October 2021

Colorectal Cancer in Uganda: A 10-Year, Facility-Based, Retrospective Study

Wekha G, Ssewante N, Iradukunda A, Jurua M, Nalwoga S, Lanyero S, Olum R, Bongomin F

Cancer Management and Research 2021, 13:7697-7707

Published Date: 7 October 2021

Women’s Satisfaction with Cervical Cancer Screening Services and Associated Factors in Maternal Health Clinics of Jimma Town Public Health Facilities, Southwest Ethiopia

Atnafu T, Daka DW, Debela TF, Ergiba MS

Cancer Management and Research 2021, 13:7685-7696

Published Date: 7 October 2021

Prevalence and Risk Factors of Nephrotoxicity Among Adult Cancer Patients at Mbarara Regional Referral Hospital

Isiiko J, Atwiine B, Oloro J

Cancer Management and Research 2021, 13:7677-7684

Published Date: 7 October 2021

MicroRNAs in Body Fluids: A More Promising Biomarker for Clear Cell Renal Cell Carcinoma

Shi L, Wang M, Li H, You P

Cancer Management and Research 2021, 13:7663-7675

Published Date: 5 October 2021

Endoscopic Ultrasound-Guided Acquisition of Portal Venous Circulating Tumor Cells as a Potential Diagnostic and Prognostic Tool for Pancreatic Cancer

Zhang Y, Su H, Wang H, Xu C, Zhou S, Zhao J, Shen S, Xu G, Wang L, Zou X, Zhang S, Lv Y

Cancer Management and Research 2021, 13:7649-7661

Published Date: 5 October 2021

Long Non-Coding RNA C1QTNF1 Antisense RNA 1 Upregulates Hexokinase 2 by Sponging microRNA-484 to Promote the Malignancy of Colorectal Cancer [Retraction]

Jin S, Liu Y, Wang W, Li Z

Cancer Management and Research 2021, 13:7647-7648

Published Date: 5 October 2021

SNHG1 Promotes Malignant Progression of Glioma by Targeting miR-140-5p and Regulating PI3K/AKT Pathway [Retraction]

Cai RD, Zhang CC, Xie LL, Wang PC, Huang CX, Chen JL, Lv HT

Cancer Management and Research 2021, 13:7645-7646

Published Date: 5 October 2021

Concurrence of Gastric Cancer and Incidental Pulmonary Embolism May Be a Prognostic Factor for Advanced Gastric Cancer Patients with Incidental Pulmonary Embolism

Qiu M, Meng Y, Wang H, Sun L, Liu Z, Kan S, Wang T, Zhang S

Cancer Management and Research 2021, 13:7637-7644

Published Date: 4 October 2021

Playing the Devil’s Advocate: Should We Give a Second Chance to mTOR Inhibition in Renal Clear Cell Carcinoma? – ie Strategies to Revert Resistance to mTOR Inhibitors

Pezzicoli G, Filoni E, Gernone A, Cosmai L, Rizzo M, Porta C

Cancer Management and Research 2021, 13:7623-7636

Published Date: 4 October 2021

By Increasing the Expression and Activation of STAT3, Sustained C5a Stimulation Increases the Proliferation, Migration, and Invasion of RCC Cells and Promotes the Growth of Transgrafted Tumors

Zheng JM, Zhou HX, Yu HY, Xia YH, Yu QX, Qu HS, Bao JQ

Cancer Management and Research 2021, 13:7607-7621

Published Date: 4 October 2021

Original Research

Comparison of Outcomes and Prognostic Factors Between Early-Stage Cervical Adenocarcinoma and Adenosquamous Carcinoma Patients After Radical Surgery and Postoperative Adjuvant Radiotherapy

Zhou Y, Wang W, Hu K, Zhang F

Cancer Management and Research 2021, 13:7597-7605

Published Date: 4 October 2021

Long Intergenic Non-Coding RNA LINC00922 Aggravates the Malignant Phenotype of Breast Cancer by Regulating the microRNA-424-5p/BDNF Axis [Retraction]

Yue X, Wang Z

Cancer Management and Research 2021, 13:7595-7596

Published Date: 4 October 2021

microRNA-548b Suppresses Aggressive Phenotypes of Hepatocellular Carcinoma by Directly Targeting High-Mobility Group Box 1 mRNA [Retraction]

Yun Z, Meng F, Jiang P, Yue M, Li S

Cancer Management and Research 2021, 13:7593-7594

Published Date: 4 October 2021

A Novel Nomogram for Prediction of Early Postoperative Complications of Total Gastrectomy for Gastric Cancer

Zhang J, Jiang L, Zhu X

Cancer Management and Research 2021, 13:7579-7591

Published Date: 2 October 2021

Palliative Care and Life-Sustaining/Local Procedures in Colorectal Cancer in the United States Hospitals: A Ten-Year Perspective

Mojtahedi Z, Koo JS, Yoo J, Kim P, Kang HT, Hwang J, Joo MK, Shen JJ

Cancer Management and Research 2021, 13:7569-7577

Published Date: 2 October 2021

Opportunistic Detection for Pancreatic Cystic Lesions During Chest Multidetector CT Scans for Lung Cancer Screening

Chen X, Yu Z, Wang J, Cui W, Cui C, Wang Y, Liu Y, Zhou H, Wang C, Wang Z, Chen X

Cancer Management and Research 2021, 13:7559-7568

Published Date: 2 October 2021

LncRNA HLA Complex Group 11 Knockdown Alleviates Cisplatin Resistance in Gastric Cancer by Targeting the miR-144-3p/UBE2D1 Axis

Li Y, Wang L, Xu X, Sun H, Wu L

Cancer Management and Research 2021, 13:7543-7557

Published Date: 1 October 2021

Circular RNA-Related CeRNA Network and Prognostic Signature for Patients with Osteosarcoma

Man G, Duan A, Liu W, Cheng J, Liu Y, Song J, Zhou H, Shen K

Cancer Management and Research 2021, 13:7527-7541

Published Date: 1 October 2021

Concomitant Pulmonary Tuberculosis Impair Survival in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Lung Adenocarcinoma Patients Receiving EGFR-Tyrosine Kinase Inhibitor

Xie Y, Su N, Zhou W, Lei A, Li X, Li W, Huang Z, Cen W, Hu J

Cancer Management and Research 2021, 13:7517-7526

Published Date: 1 October 2021

The Preoperative Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio Predicts Disease-Free Survival in Resectable Esophageal Squamous Cell Carcinoma

Zheng Z, Yang C, Cai C, Zhu H

Cancer Management and Research 2021, 13:7511-7516

Published Date: 1 October 2021

Long Non-Coding RNA UBA6-AS1 Promotes the Malignant Properties of Glioblastoma by Competitively Binding to microRNA-760 and Enhancing Homeobox A2 Expression [Retraction]

Cheng F, Liu J, Zhang Y, You Q, Chen B, Cheng J, Deng C

Cancer Management and Research 2021, 13:7509-7510

Published Date: 30 September 2021

Long Noncoding RNA LINC00173 Promotes the Malignancy of Melanoma by Promoting the Expression of IRS4 Through Competitive Binding to microRNA-493 [Retraction]

Yang F, Lei P, Zeng W, Gao J, Wu N

Cancer Management and Research 2021, 13:7507-7508

Published Date: 29 September 2021

Long Non-Coding RNA LINC00491 Contributes to the Malignancy of Non-Small-Cell Lung Cancer via Competitively Binding to microRNA-324-5p and Thereby Increasing Specificity Protein 1 Expression [Retraction]

Zhang X, Zhao X, Wang Y, Xing L

Cancer Management and Research 2021, 13:7505-7506

Published Date: 29 September 2021

Clinical Characteristics and Therapeutic Outcomes of Metastatic Peritoneal Carcinomatosis in Non-Small-Cell Lung Cancer

Tani T, Nakachi I, Ikemura S, Nukaga S, Ohgino K, Kuroda A, Terai H, Masuzawa K, Shinozaki T, Ishioka K, Funatsu Y, Koh H, Fukunaga K, Soejima K

Cancer Management and Research 2021, 13:7497-7503

Published Date: 29 September 2021

Long Noncoding RNA DLGAP1-AS1 Promotes the Aggressive Behavior of Gastric Cancer by Acting as a ceRNA for microRNA-628-5p and Raising Astrocyte Elevated Gene 1 Expression [Retraction]

Deng J, Zhang Q, Lu L, Fan C

Cancer Management and Research 2021, 13:7495-7496

Published Date: 28 September 2021

Long Noncoding RNA SNHG16 Silencing Inhibits the Aggressiveness of Gastric Cancer via Upregulation of microRNA-628-3p and Consequent Decrease of NRP1 [Retraction]

Pang W, Zhai M, Wang Y, Li Z

Cancer Management and Research 2021, 13:7493-7494

Published Date: 28 September 2021

Long Noncoding RNA FGD5-AS1 Acts as a Competing Endogenous RNA on microRNA-383 to Enhance the Malignant Characteristics of Esophageal Squamous Cell Carcinoma by Increasing SP1 Expression [Retraction]

Gao J, Zhang Z, Su H, Zong L, Li Y

Cancer Management and Research 2021, 13:7491-7492

Published Date: 28 September 2021

microRNA-877 Inhibits Malignant Progression of Colorectal Cancer by Directly Targeting MTDH and Regulating the PTEN/Akt Pathway [Retraction]

Zhang L, Li C, Cao L, Li H, Zou H, Li H, Pei H

Cancer Management and Research 2021, 13:7489-7490

Published Date: 28 September 2021

Global Analysis of Research Trends on Kidney Function After Nephron-Sparing Surgery: A Bibliometric and Visualised Study

Abushamma F, Barqawi A, Al-Jabi SW, Akkawi M, Maree M, Zyoud SH

Cancer Management and Research 2021, 13:7479-7487

Published Date: 27 September 2021

Development and Validation of Artificial Neural Networks for Survival Prediction Model for Patients with Spontaneous Hepatocellular Carcinoma Rupture After Transcatheter Arterial Embolization

Qiu Y, Wang T, Yang X, Shen S, Yang Y, Wang W

Cancer Management and Research 2021, 13:7463-7477

Published Date: 27 September 2021

Comparison of Perioperative Outcomes Between Laparoscopic and Open Partial Nephrectomy for Different Complexity Renal Cell Carcinoma Based on the R.E.N.A.L. Nephrometry Score

Yu Y, Wang W, Xiong Z, Yang Z, Li J, Shen Y, Gu B

Cancer Management and Research 2021, 13:7455-7461

Published Date: 28 September 2021

Anemia is a Prognostic Factor for Overall Survival Rate in Patients with Non-Small Cell Lung Cancer Treated with Stereotactic Body Radiation Therapy

Tanaka H, Ono T, Manabe Y, Kajima M, Fujimoto K, Yuasa Y, Shiinoki T, Yamaji Y, Matsunaga K

Cancer Management and Research 2021, 13:7447-7453

Published Date: 27 September 2021

Original Research

Changes in Carcinoid Syndrome Symptoms Among Patients Receiving Telotristat Ethyl in US Clinical Practice: Findings from the TELEPRO-II Real-World Study

Kulke MH, Kennecke HF, Murali K, Joish VN

Cancer Management and Research 2021, 13:7439-7446

Published Date: 27 September 2021

Predict Lymph Node Metastasis in Penile Cancer Using Clinicopathological Factors and Nomograms

Shao Y, Tu X, Liu Y, Bao Y, Ren S, Yang Z, Hu X, Wu K, Zeng H, Wei Q, Li X

Cancer Management and Research 2021, 13:7429-7437

Published Date: 24 September 2021

Effective Immunosurveillance After Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia

Kunadt D, Stölzel F

Cancer Management and Research 2021, 13:7411-7427

Published Date: 24 September 2021

Role of Cytokines Released During Pyroptosis in Non-Small Cell Lung Cancer

Huang Y, Zhang G, Zhu Q, Wu X, Wu L

Cancer Management and Research 2021, 13:7399-7409

Published Date: 24 September 2021

Chronic Progression of Lung Cancer Recurrence After Surgery: Warning Role of Postoperative Pneumonia

Lin D, Zhu J, Xu X, Xiao K, Wen X, Zheng Q, Zhou Y, Cai X

Cancer Management and Research 2021, 13:7387-7398

Published Date: 24 September 2021

The Prognostic Impact of Preoperative Serum Apolipoprotein A-I in Patients with Esophageal Basaloid Squamous Cell Carcinoma

Feng JF, Zhao JM, Yang X, Wang L

Cancer Management and Research 2021, 13:7373-7385

Published Date: 22 September 2021

Genotype Distribution and Prevalence of Human Papillomavirus Infection in Women in Northern Jiangsu Province of China

Wang L, Chen G, Jiang J

Cancer Management and Research 2021, 13:7365-7372

Published Date: 22 September 2021

Obesity Promotes Tumor Immune Evasion in Ovarian Cancer Through Increased Production of Myeloid-Derived Suppressor Cells via IL-6

Yang Q, Yu B, Kang J, Li A, Sun J

Cancer Management and Research 2021, 13:7355-7363

Published Date: 21 September 2021

Intratumoral Injection of a Human Papillomavirus Therapeutic Vaccine-Induced Strong Anti-TC-1-Grafted Tumor Activity in Mice

Che Y, Yang Y, Suo J, Chen C, Wang X

Cancer Management and Research 2021, 13:7339-7354

Published Date: 21 September 2021

Plasma circRNAs as Biomarkers in Cancer

Zhou Q, Ju LL, Ji X, Cao YL, Shao JG, Chen L

Cancer Management and Research 2021, 13:7325-7337

Published Date: 21 September 2021

Myelin and Lymphocyte Protein (MAL): A Novel Biomarker for Uterine Corpus Endometrial Carcinoma

Li D, Zhang J, Wu L, Yang X, Chen Z, Yuan J

Cancer Management and Research 2021, 13:7311-7323

Published Date: 21 September 2021

SP1-Regulated Non-Coding RNA SNHG22 Promotes Ovarian Cancer Growth and Glycolysis

Guan N, Zheng H, Wu X, Xie L, Tong X

Cancer Management and Research 2021, 13:7299-7309

Published Date: 21 September 2021

Imaging Features and Prognostic Value of FDG PET/CT in Patients with Intravascular Large B-Cell Lymphoma

Lim CH, Yoon SE, Kim WS, Lee KH, Kim SJ

Cancer Management and Research 2021, 13:7289-7297

Published Date: 21 September 2021

lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis

Dang Y, Zhou Y, Ou X, Wang Q, Wei D, Xie F

Cancer Management and Research 2021, 13:7277-7288

Published Date: 21 September 2021

HNRNPC Promotes Proliferation, Metastasis and Predicts Prognosis in Prostate Cancer

Wang S, Xu G, Chao F, Zhang C, Han D, Chen G

Cancer Management and Research 2021, 13:7263-7276

Published Date: 21 September 2021

Expression and Clinical Significance of the NCAPH, AGGF1, and FOXC2 Proteins in Serous Ovarian Cancer

Sun Y, Wang X, Wen H, Zhu B, Yu L

Cancer Management and Research 2021, 13:7253-7262

Published Date: 21 September 2021

LncRNA MALAT1 Promotes Survival of Epithelial Ovarian Cancer Cells by Downregulating miR-145-5p [Retraction]

Wang K, Zhao Y, Wang YM

Cancer Management and Research 2021, 13:7251-7252

Published Date: 19 September 2021

microRNA-26a Directly Targeting MMP14 and MMP16 Inhibits the Cancer Cell Proliferation, Migration and Invasion in Cutaneous Squamous Cell Carcinoma [Retraction]

Zheng W, Li ZY, Zhao DL, Li XL, Liu R

Cancer Management and Research 2021, 13:7249-7250

Published Date: 18 September 2021

MicroRNA-802 Inhibits Cell Proliferation and Induces Apoptosis in Human Laryngeal Cancer by Targeting cAMP-Regulated Phosphoprotein 19 [Retraction]

Ye H, Jin Q, Wang X, Li Y

Cancer Management and Research 2021, 13:7247-7248

Published Date: 18 September 2021

MicroRNA-665 Inhibits the Oncogenicity of Retinoblastoma by Directly Targeting High-Mobility Group Box 1 and Inactivating the Wnt/β-Catenin Pathway [Retraction]

Wang S, Du S, Lv Y, Zhang F, Wang W

Cancer Management and Research 2021, 13:7245-7246

Published Date: 18 September 2021

MicroRNA-876 is Sponged by Long Noncoding RNA LINC00707 and Directly Targets Metadherin to Inhibit Breast Cancer Malignancy [Retraction]

Li T, Li Y, Sun H

Cancer Management and Research 2021, 13:7243-7244

Published Date: 18 September 2021

A Systematic Review of Cancer of Unknown Primary in the Head and Neck Region

Pinkiewicz M, Dorobisz K, Zatoński T

Cancer Management and Research 2021, 13:7235-7241

Published Date: 18 September 2021

SOX10 Knockdown Inhibits Melanoma Cell Proliferation via Notch Signaling Pathway

Tang Y, Cao Y

Cancer Management and Research 2021, 13:7225-7234

Published Date: 17 September 2021

Overexpression of the lncRNA AC012213.3 Promotes Proliferation, Migration and Invasion of Breast Cancer via RAD54B/PI3K/AKT Axis and is Associated with Worse Patient Prognosis

Zhong H, Zeng G, He L

Cancer Management and Research 2021, 13:7213-7223

Published Date: 16 September 2021

Radiation Oncologists’ Approach to Internal Mammary Lymph Node Radiotherapy in Breast Cancer: The Turkish Society for Radiation Oncology Breast Cancer Study Group (TROD 06-005 Survey Study)

Ay Eren A, Eren MF

Cancer Management and Research 2021, 13:7203-7212

Published Date: 16 September 2021

Efficacy and Prognosis of First-Line EGFR-Tyrosine Kinase Inhibitor Treatment in Older Adults Including Poor Performance Status Patients with EGFR-Mutated Non-Small-Cell Lung Cancer

Chang CY, Chen CY, Chang SC, Lai YC, Wei YF

Cancer Management and Research 2021, 13:7187-7201

Published Date: 15 September 2021

Identification of Novel Pyroptosis-Related lncRNAs Associated with the Prognosis of Breast Cancer Through Interactive Analysis

Gao L, Li Q

Cancer Management and Research 2021, 13:7175-7186

Published Date: 15 September 2021

Real-World Analysis of the Efficacy and Safety of a Novel Irreversible HER2 Tyrosine Kinase Inhibitor Pyrotinib in Patients with HER2-Positive Metastatic Breast Cancer

Sun Y, Chen B, Li J, Peng L, Li S, Yu X, Li L

Cancer Management and Research 2021, 13:7165-7174

Published Date: 14 September 2021

Factors Associated with Pre- and Post-Educational Intervention Knowledge Levels of HPV and Cervical Cancer Among the Male and Female University Students, Northwest Ethiopia

Indracanti M, Berhane N, Minyamer T

Cancer Management and Research 2021, 13:7149-7163

Published Date: 14 September 2021

Original Research

Low Dose of Lenvatinib Treatment for Patients of Radioiodine-Refractory Differentiated Thyroid Carcinoma – A Real-World Experience

Jiang HJ, Chang YH, Chen YH, Wu CW, Wang PW, Hsiao PJ

Cancer Management and Research 2021, 13:7139-7148

Published Date: 14 September 2021

A Preliminary Study of the Complement Component 1q Levels in Predicting the Efficacy of Combined Immunotherapy in Patients with Lung Cancer

Zhang D, Li Y, Li H, Tang T, Zheng Y, Guo X, Xu X

Cancer Management and Research 2021, 13:7131-7137

Published Date: 10 September 2021

Comprehensive Analysis to Identify Enhancer-Regulated Inflammation-Associated Genes in Lung Adenocarcinoma

Li X, Li X, Ding L

Cancer Management and Research 2021, 13:7115-7129

Published Date: 11 September 2021

Emerging Roles of N6-Methyladenosine Demethylases and Its Interaction with Environmental Toxicants in Digestive System Cancers

Liu C, Yang S, Zhang Y, Wang C, Du D, Wang X, Liu T, Liang G

Cancer Management and Research 2021, 13:7101-7114

Published Date: 9 September 2021

TGF-β-MTA1-SMAD7-SMAD3-SOX4-EZH2 Signaling Axis Promotes Viability, Migration, Invasion and EMT of Hepatocellular Carcinoma Cells

Zhang K, Fang T, Shao Y, Wu Y

Cancer Management and Research 2021, 13:7087-7099

Published Date: 10 September 2021

Role of Phenotypes of Circulating Tumor Cells in the Diagnosis and Treatment of Colorectal Cancer

Zhong Y, Ma T, Qiao T, Hu H, Li Z, Luo K, Wang Y, Tang Q, Wang G, Huang R, Wang X

Cancer Management and Research 2021, 13:7077-7085

Published Date: 10 September 2021

Explore the Value of Adding Induction Chemotherapy to Concurrent Chemoradiotherapy in T3-4N0M0 Nasopharyngeal Carcinoma Patients: A Retrospective Study

Li P, Zhang Q, Luo D, Jiang F, Jin Q, Hua Y, Jin T, Chen X

Cancer Management and Research 2021, 13:7067-7076

Published Date: 9 September 2021

Preoperative Visualized Ultrasound Assessment of the Recurrent Laryngeal Nerve in Thyroid Cancer Surgery: Reliability and Risk Features by Imaging

He Y, Li Z, Yang Y, Lei J, Peng Y

Cancer Management and Research 2021, 13:7057-7066

Published Date: 10 September 2021

Assessment of Potential Prognostic Value of Peroxiredoxin 1 in Oral Squamous Cell Carcinoma [Corrigendum]

Shen Y, Xu H, Li L, Lu Y, Zhang M, Huang X, Tang X

Cancer Management and Research 2021, 13:7055-7056

Published Date: 10 September 2021

Treatment with Anlotinib After Chemotherapy and EGFR-TKI Resistance in Lung Adenosquamous Carcinoma with Concurrent EGFR and PIK3CA Mutations: A Case Report and Literature Review

Wu Y, Zhang K, Guan J, Wu W, Zhang J, Chen H

Cancer Management and Research 2021, 13:7047-7053

Published Date: 9 September 2021

Targeting Notch4 in Cancer: Molecular Mechanisms and Therapeutic Perspectives

Xiu M, Zeng X, Shan R, Wen W, Li J, Wan R

Cancer Management and Research 2021, 13:7033-7045

Published Date: 8 September 2021

Review

Knowing When to Use Stereotactic Ablative Radiation Therapy in Oligometastatic Cancer

Franceschini D, Teriaca MA, Dominici L, Franzese C, Scorsetti M

Cancer Management and Research 2021, 13:7009-7031

Published Date: 7 September 2021

Original Research

Practice and Associated Factors of Human Papillomavirus Vaccination Among Primary School Students in Minjar-Shenkora District, North Shoa Zone, Amhara Regional State, Ethiopia, 2020

Kassa HN, Bilchut AH, Mekuria AD, Lewetie EM

Cancer Management and Research 2021, 13:6999-7008

Published Date: 7 September 2021

The Neutrophil-to-Lymphocyte Ratio (NLR) Predicts the Prognosis of Unresectable Intermediate and Advanced Hepatocellular Carcinoma Treated with Apatinib

Wang H, Wang Z, Hou Z, Yang X, Zhu K, Cao M, Zhu X, Li H, Zhang T

Cancer Management and Research 2021, 13:6989-6998

Published Date: 7 September 2021

A CLDN18.2-Targeting Bispecific T Cell Co-Stimulatory Activator for Cancer Immunotherapy

Liang J, Zhang H, Huang Y, Fan L, Li F, Li M, Yan Y, Zhang J, Li Z, Yang X

Cancer Management and Research 2021, 13:6977-6987

Published Date: 7 September 2021

Efficacy and Prognostic Analysis of 315 Stage I–IVa Esophageal Cancer Patients Treated with Simultaneous Integrated Boost-Intensity-Modulated Radiation Therapy

Cai P, Yang Y, Li DJ

Cancer Management and Research 2021, 13:6969-6975

Published Date: 7 September 2021

Impact of the Extent of Thyroidectomy on Quality of Life in Differentiated Thyroid Cancer Survivors: A Propensity Score Matched Analysis

Yang X, Yang Q, Tang Y, Ma J, Ye H

Cancer Management and Research 2021, 13:6953-6967

Published Date: 7 September 2021

Transcatheter Arterial Embolization Containing Donafenib Induces Anti-Angiogenesis and Tumoricidal CD8+ T-Cell Infiltration in Rabbit VX2 Liver Tumor

Shi Q, Li T, Huang S, Bai Y, Wang Y, Liu J, Zhou C, Chen Y, Xiong B

Cancer Management and Research 2021, 13:6943-6952

Published Date: 7 September 2021

Increased Liquefactive Necrosis Formation After Transarterial Chemoembolization Combined with Molecular Targeted Agents Plus Immune Checkpoint Inhibitors for Hepatocellular Carcinoma

Wang Y, Zhou C, Liu J, Shi Q, Huang S, Yang C, Li T, Chen Y, Xiong B

Cancer Management and Research 2021, 13:6935-6941

Published Date: 7 September 2021

Study on the Value of DCE-MRI in Differentiating Glossitis and Tongue Cancer and the Intratumour Heterogeneity

Liu F, Zhao M, Lu S, Kang L

Cancer Management and Research 2021, 13:6925-6934

Published Date: 4 September 2021

CT-Based Radiomics Nomogram for Prediction of Progression-Free Survival in Locoregionally Advanced Nasopharyngeal Carcinoma

Yan C, Shen DS, Chen XB, SU DK, Liang ZG, Chen KH, Li L, Liang X, Liao H, Zhu XD

Cancer Management and Research 2021, 13:6911-6923

Published Date: 3 September 2021

Comparison of Different EGFR Gene Mutation Status in Patients with Metastatic Non-Small Lung Cancer After First-Line EGFR-TKIs Therapy and Analyzing Its Relationship with Efficacy and Prognosis

Yuan C, Jiang H, Jiang W, Wang H, Su C, Zhou S

Cancer Management and Research 2021, 13:6901-6910

Published Date: 3 September 2021

Is There a Regular Pattern in the Recovery of Parathyroid Function After Thyroid Cancer Surgery?

Yao XY, Zhou Y, Chen SJ, Wu Y, Bian C, Chen H, Liu H

Cancer Management and Research 2021, 13:6891-6899

Published Date: 3 September 2021

MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells

Liu C, Han X, Li B, Huang S, Zhou Z, Wang Z, Wang W

Cancer Management and Research 2021, 13:6879-6889

Published Date: 1 September 2021

HPV Genotype Specific and Age Stratified Immediate Prevalence of Cervical Precancers and Cancers in Women with NILM/hrHPV+: A Single Center Retrospective Study of 26,228 Cases

Liu Q, Zhou X, Zhang X, Strickland AL, zheng W, Chen H, Zhou F

Cancer Management and Research 2021, 13:6869-6877

Published Date: 2 September 2021

Effect of Ultrasound-Guided Quadratus Lumborum Block Preemptive Analgesia on Postoperative Recovery of Patients with Open Radical Colon Cancer Surgery: A Retrospective Study

Wang Y, Hu H, Feng C, Liu D, Ding N

Cancer Management and Research 2021, 13:6859-6867

Published Date: 1 September 2021

Laparoscopic Gastrojejunostomy with Conversion Therapy in Gastric Outlet Obstruction Caused by Incurable Advanced Gastric Cancer

Wang C, Lin S, Zhang X, Yang C, Li W

Cancer Management and Research 2021, 13:6847-6857

Published Date: 1 September 2021

Efficacy and Safety of Individualized Schedule of Sunitinib by Drug Monitoring in Patients with Metastatic Renal Cell Carcinoma

Zhu X, Zhang X, Sun G, Liu Z, Zhang H, Yang Y, Ni Y, Dai J, Zhu S, Chen J, Zhao J, Wang Z, Zeng H, Shen P

Cancer Management and Research 2021, 13:6833-6845

Published Date: 31 August 2021

Correlation Between Enhancement Patterns on Transabdominal Ultrasound and Survival for Pancreatic Ductal Adenocarcinoma

Zhou T, Tan L, Gui Y, Zhang J, Chen X, Dai M, Xiao M, Zhang Q, Chang X, Xu Q, Bai C, Cheng Y, Xu Q, Wang X, Meng H, Jia W, Lv K, Jiang Y

Cancer Management and Research 2021, 13:6823-6832

Published Date: 31 August 2021

circTADA2A Retards the Progression of Colorectal Cancer via Regulating miR-1229/BCL2L10 Signal Axis

Hu L, Fang L, Zhang Z, Yan Z

Cancer Management and Research 2021, 13:6811-6821

Published Date: 1 September 2021

Prognostic Value of Inflammatory Markers in Nasopharyngeal Carcinoma Patients in the Intensity-Modulated Radiotherapy Era

Li Q, Yu L, Yang P, Hu Q

Cancer Management and Research 2021, 13:6799-6810

Published Date: 31 August 2021

Assessment of Potential Prognostic Value of Peroxiredoxin 1 in Oral Squamous Cell Carcinoma [Corrigendum]

Shen Y, Xu H, Li L, Lu Y, Zhang M, Huang X, Tang X

Cancer Management and Research 2021, 13:6797-6798

Published Date: 31 August 2021

Role of Bclaf1 in Promoting Adrenocortical Carcinoma Proliferation: A Study Combining the Use of Bioinformatics and Molecular Events

Zhou H, Zou M, Ding X, Zou F

Cancer Management and Research 2021, 13:6785-6795

Published Date: 31 August 2021

Original Research

One-Year Mortality in Patients with Cancer Cachexia: Association with Albumin and Total Protein

Liu XY, Zhang X, Ruan GT, Zhang KP, Tang M, Zhang Q, Song MM, Zhang XW, Ge YZ, Yang M, Xu HX, Song CH, Shi HP

Cancer Management and Research 2021, 13:6775-6783

Published Date: 29 August 2021

Factors Prognostic for Brain Metastases from Colorectal Cancer: A Single-Center Experience in China

Wang D, Chen C, Ge X, Yang Q, Huang Y, Ling T, Jin T, Yu S, Wang J, Sun L

Cancer Management and Research 2021, 13:6767-6774

Published Date: 29 August 2021

Original Research

Real-World Outcome and Prognostic Factors of Pazopanib in Advanced Soft Tissue Sarcoma

Alshamsan B, Badran A, Alshibany A, Maraiki F, Elshenawy MA, Elhassan T, Atallah JP

Cancer Management and Research 2021, 13:6755-6766

Published Date: 29 August 2021

Transcriptome Signature of Immune Cells Post Reovirus Treatment in KRAS Mutated Colorectal Cancer

Fogel EJ, Samouha A, Goel S, Maitra R

Cancer Management and Research 2021, 13:6743-6754

Published Date: 27 August 2021

Conditional Survival and Annual Hazard Estimates of Classical Hodgkin Lymphoma

Nuersulitan R, Yang M, Mi L, Wu M, Liu X, Ping L, Xie Y, Liu W, Song Y, Zhu J

Cancer Management and Research 2021, 13:6731-6741

Published Date: 26 August 2021

Cost-Effectiveness Analysis of Active Surveillance Compared to Early Surgery in Small Papillary Thyroid Cancer: A Systemic Review

Baek HS, Jeong CH, Ha J, Bae JS, Kim JS, Lim DJ, Kim CM

Cancer Management and Research 2021, 13:6721-6730

Published Date: 26 August 2021

Review

Therapeutic Options in Unresectable Oral Squamous Cell Carcinoma: A Systematic Review

Madera M, Tirado Amador L, Leal Acosta C

Cancer Management and Research 2021, 13:6705-6719

Published Date: 25 August 2021

Ibero-American Expert Consensus on Squamous Cell Carcinoma of the Head and Neck Treatment in Patients Unable to Receive Cisplatin: Recommendations for Clinical Practice

Falco A, de Oliveira TB, Cacicedo J, Ospina AV, Ticona MÁ, Galindo H, Pereira MD, Aguilar-Ponce JL, Rueda-Domínguez A, Soria T, Taberna M, Iglesias L, Sowley T, Mesía R

Cancer Management and Research 2021, 13:6689-6703

Published Date: 26 August 2021

Prognostic Value of an m5C RNA Methylation Regulator-Related Signature for Clear Cell Renal Cell Carcinoma

Li H, Jiang H, Huang Z, Chen Z, Chen N

Cancer Management and Research 2021, 13:6673-6687

Published Date: 24 August 2021

Biogenesis, Functions, and Role of CircRNAs in Lung Cancer

Dong H, Zhou J, Cheng Y, Wang M, Wang S, Xu H

Cancer Management and Research 2021, 13:6651-6671

Published Date: 24 August 2021

The Effect of Parathyroid Gland Autotransplantation on Hypoparathyroidism After Thyroid Surgery for Papillary Thyroid Carcinoma

Wang B, Zhu CR, Yao XM, Wu J

Cancer Management and Research 2021, 13:6641-6650

Published Date: 24 August 2021

Development and Validation of a Nomogram for Predicting Recurrence-Free Survival of Surgical Resected Retroperitoneal Liposarcoma

Zhuang A, Wu Q, Tong H, Zhang Y, Lu W

Cancer Management and Research 2021, 13:6633-6639

Published Date: 24 August 2021

Temporal Muscle Thickness is an Independent Prognostic Biomarker in Patients with Glioma: Analysis of 261 Cases

Yan OY, Teng HB, Fu SN, Chen YZ, Liu F

Cancer Management and Research 2021, 13:6621-6632

Published Date: 24 August 2021

Risk Prediction and Treatment of LE-DVT in Patients with Chronic Radiation Intestinal Injury: A Retrospective Case–Control Study

Huang X, Kuang Y, Qin Q, Zhu M, He Y, Yuan Z, Wang H, Zhong Q, Guan Q, Wang H, Ma T, Fan X

Cancer Management and Research 2021, 13:6611-6619

Published Date: 23 August 2021

CircRNA DUSP16 Knockdown Suppresses Colorectal Cancer Progression by Regulating the miR-432-5p/E2F6 Axis

Wang G, Yang H

Cancer Management and Research 2021, 13:6599-6609

Published Date: 21 August 2021

Identification and Functional Validation of Differentially Expressed microRNAs in Ascites-Derived Ovarian Cancer Cells Compared with Primary Tumour Tissue

Jiang Y, Shi Y, Lyu T, Liu H, Shen L, Zhou T, Feng W

Cancer Management and Research 2021, 13:6585-6597

Published Date: 21 August 2021

Extranodal NK/T-Cell Lymphoma Occurring Primarily in the Eyes and with Central Nervous System Relapse

Wei C, Zhang L, Zhang W, Zhou D

Cancer Management and Research 2021, 13:6579-6583

Published Date: 20 August 2021

The Prognostic Value of FGFR3 Expression in Patients with T1 Non-Muscle Invasive Bladder Cancer

Sikic D, Taubert H, Breyer J, Eckstein M, Weyerer V, Keck B, Kubon J, Otto W, Worst TS, Kriegmair MC, Erben P, Hartmann A, Wullich B, Wirtz RM, Wach S

Cancer Management and Research 2021, 13:6567-6578

Published Date: 20 August 2021

Review

Prognostic Factors in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative (HR+/HER2–) Advanced Breast Cancer: A Systematic Literature Review

Cuyún Carter G, Mohanty M, Stenger K, Morato Guimaraes C, Singuru S, Basa P, Singh S, Tongbram V, Kuemmel S, Guarneri V, Tolaney SM

Cancer Management and Research 2021, 13:6537-6566

Published Date: 20 August 2021

The Role and Significance of Wnt5a in Regulating Epithelial–Mesenchymal Transition in Endometrioid Adenocarcinoma

Yang N, Chen H, Huang Y, Song X, Yang P, Zhang S, Yan W, Li N, Feng Z

Cancer Management and Research 2021, 13:6527-6535

Published Date: 20 August 2021

Diagnostic Value of Serum lncRNA HOTAIR Combined with Galectin-3 in Benign and Papillary Thyroid Carcinoma

Li L, Wang J, Li Z, Qiu S, Cao J, Zhao Y, Huang Z, He J, Luo F, Yang K

Cancer Management and Research 2021, 13:6517-6525

Published Date: 19 August 2021

Review

The Versatile Functions of G. Lucidum Polysaccharides and G. Lucidum Triterpenes in Cancer Radiotherapy and Chemotherapy

Xu J, Chen F, Wang G, Liu B, Song H, Ma T

Cancer Management and Research 2021, 13:6507-6516

Published Date: 17 August 2021

A Cytoplasm-Enriched circRNA circ-MYBL2 is Downregulated in Non-Small Cell Lung Cancer and Sponges Oncogenic miR-28 to Regulate Cancer Cell Proliferation and Apoptosis

Mao Y, Wang C

Cancer Management and Research 2021, 13:6499-6506

Published Date: 16 August 2021

Aberration of lncRNA LINC00460 is a Promising Prognosis Factor and Associated with Progression of Clear Cell Renal Cell Carcinoma

Zhang S, Zhang F, Niu Y, Yu S

Cancer Management and Research 2021, 13:6489-6497

Published Date: 16 August 2021

Development of a New Recurrence-Free Survival Prediction Nomogram for Patients with Primary Non-Muscle-Invasive Bladder Cancer Based on Preoperative Controlling Nutritional Status Score

Zhao L, Sun J, Wang K, Tai S, Hua R, Yu Y, Fan Y, Huang J

Cancer Management and Research 2021, 13:6473-6487

Published Date: 16 August 2021

Analysis of m6A-Related lncRNAs for Prognosis Value and Response to Immune Checkpoint Inhibitors Therapy in Hepatocellular Carcinoma

Wang Y, Li N, Tian D, Zhou CW, Wang YH, Yang C, Zeng MS

Cancer Management and Research 2021, 13:6451-6471

Published Date: 16 August 2021

Systemic Inflammation Response Index is an Independent Prognostic Indicator for Patients with Renal Cell Carcinoma Undergoing Laparoscopic Nephrectomy: A Multi-Institutional Cohort Study

Mao W, Sun S, He T, Jin X, Wu J, Xu B, Zhang G, Wang K, Chen M

Cancer Management and Research 2021, 13:6437-6450

Published Date: 16 August 2021

Original Research

Prognostic Value of Ki-67 Expression in Advanced Lung Squamous Cell Carcinoma Patients Treated with Chemotherapy

Wang D, Ye W, Shi Q

Cancer Management and Research 2021, 13:6429-6436

Published Date: 14 August 2021

Elevated mRNA Level of Y-Box Binding Protein 1 Indicates Unfavorable Prognosis Correlated with Macrophage Infiltration and T Cell Exhaustion in Luminal Breast Cancer

Lv Z, Xue C, Zhang L, Sun J, Bo C

Cancer Management and Research 2021, 13:6411-6428

Published Date: 14 August 2021

Primary Laparoscopic Surgery Does Not Affect the Prognosis of Early-Stage Ovarian Clear Cell Cancer

Yin S, Gao W, Shi P, Xi M, Tang W, Zhang J

Cancer Management and Research 2021, 13:6403-6409

Published Date: 14 August 2021

Different Clinicopathologic and Computed Tomography Imaging Characteristics of Primary and Acquired EGFR T790M Mutations in Patients with Non-Small-Cell Lung Cancer

Hou D, Li W, Wang S, Huang Y, Wang J, Tang W, Zhou L, Qi L, Wu N, Zhao S

Cancer Management and Research 2021, 13:6389-6401

Published Date: 13 August 2021

βKlotho Inhibits Cell Proliferation by Downregulating ELK4 and Predicts Favorable Prognosis in Prostate Cancer

Mao C, Dong W, Lu J, Zhang Z, Wu H, Ghavamian A, Bi D, Gao P, Liu Z, Ding S

Cancer Management and Research 2021, 13:6377-6387

Published Date: 12 August 2021

PD-L1 Protein Expression and Gene Amplification Correlate with the Clinicopathological Characteristics and Prognosis of Lung Squamous Cell Carcinoma

Chen Z, Zhao N, Wang Q, Xi Y, Tian X, Wu H, Xu Y

Cancer Management and Research 2021, 13:6365-6375

Published Date: 12 August 2021

Impact of the Time Interval Between Primary Debulking Surgery and Start of Adjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer [Corrigendum]

Lin H, Chen WH, Wu CH, Ou YC, Chen YJ, Chen YY, Lin YH, Fu HC

Cancer Management and Research 2021, 13:6363-6364

Published Date: 11 August 2021

MicroRNA-148a-3p Directly Targets SERPINE1 to Suppress EMT-Mediated Colon Adenocarcinoma Progression

Hu B, Chen Z, Wang X, Chen F, Song Z, Cao C

Cancer Management and Research 2021, 13:6349-6362

Published Date: 11 August 2021

Association of Tumour Microenvironment with Protein Glycooxidation, DNA Damage, and Nitrosative Stress in Colorectal Cancer

Zińczuk J, Zaręba K, Kamińska J, Koper-Lenkiewicz OM, Dymicka-Piekarska V, Pryczynicz A, Guzińska-Ustymowicz K, Kędra B, Matowicka-Karna J, Żendzian-Piotrowska M, Zalewska A, Maciejczyk M

Cancer Management and Research 2021, 13:6329-6348

Published Date: 12 August 2021

Analysis of Factors Related to Lymph Node Metastasis in Early-Stage Type 1 Endometrial Cancer: Verifying the Clinical Value of Positive Threshold of the Immunohistochemical Parameter Ki67

Jiang P, Yuan R

Cancer Management and Research 2021, 13:6319-6328

Published Date: 10 August 2021

Treatment and Prognosis of Solid and Cystic Brain Metastases in Patients with Non-Small-Cell Lung Cancer

Xu YB, Zhang Y, Song Z, Wang W, Shao L

Cancer Management and Research 2021, 13:6309-6317

Published Date: 10 August 2021

Review

The Crucial Roles of Intermediate Metabolites in Cancer

Huang S, Wang Z, Zhao L

Cancer Management and Research 2021, 13:6291-6307

Published Date: 10 August 2021

Diverse Distribution and Gene Expression on the 21-Gene Recurrence Assay in Breast Cancer Patients with Locoregional Recurrence Versus Distant Metastasis

Lu Y, Tong Y, Huang J, Lin L, Wu J, Fei X, Chen X, Shen K

Cancer Management and Research 2021, 13:6279-6289

Published Date: 10 August 2021

The Prognostic Value of Systemic Inflammation Response Index in Cholangiocarcinoma Patients

Jin B, Hu W, Su S, Xu H, Lu X, Sang X, Yang H, Mao Y, Du S

Cancer Management and Research 2021, 13:6263-6277

Published Date: 10 August 2021

Bead-Based Isolation of Circulating Tumor DNA from Pancreatic Cancer Patients Enables High Fidelity Next Generation Sequencing

Balendran-Braun S, Kieler M, Liebmann-Reindl S, Unseld M, Bianconi D, Prager GW, Streubel B

Cancer Management and Research 2021, 13:6249-6261

Published Date: 7 August 2021

Drug-Eluting Beads Bronchial Arterial Chemoembolization in Treating Relapsed/Refractory Small Cell Lung Cancer Patients: Results from a Pilot Study

Lin H, Wang Q, Tian F, Zhang R, Mu M, Zhao W, Bao P

Cancer Management and Research 2021, 13:6239-6248

Published Date: 7 August 2021

Alterations of Signaling Pathways in Essential Thrombocythemia with Calreticulin Mutation

Hui W, Zhang W, Liu C, Wan S, Sun W, Su L

Cancer Management and Research 2021, 13:6231-6238

Published Date: 7 August 2021

Long Non-Coding RNA Myosin Light Chain Kinase Antisense 1 Plays an Oncogenic Role in Gallbladder Carcinoma by Promoting Chemoresistance and Proliferation

Li Y, Tian M, Zhang D, Zhuang Y, Li Z, Xie S, Sun K

Cancer Management and Research 2021, 13:6219-6230

Published Date: 7 August 2021

Original Research

Myeloprotective Effects of Trilaciclib Among Patients with Small Cell Lung Cancer at Increased Risk of Chemotherapy-Induced Myelosuppression: Pooled Results from Three Phase 2, Randomized, Double-Blind, Placebo-Controlled Studies

Hussein M, Maglakelidze M, Richards DA, Sabatini M, Gersten TA, Lerro K, Sinielnikov I, Spira A, Pritchett Y, Antal JM, Malik R, Beck JT

Cancer Management and Research 2021, 13:6207-6218

Published Date: 9 August 2021

The Real-World Practice of Fruquintinib for Chinese Patients with Metastatic Colorectal Cancer

Song Y, Qu T, Zhang H, Sun Y, Cui C, Chi Y, Zhang W, Wang X, Yang L

Cancer Management and Research 2021, 13:6199-6205

Published Date: 7 August 2021

Psychosocial Burden and Quality of Life of Lung Cancer Patients: Results of the EORTC QLQ-C30/QLQ-LC29 Questionnaire and Hornheide Screening Instrument

Koch M, Gräfenstein L, Karnosky J, Schulz C, Koller M

Cancer Management and Research 2021, 13:6191-6197

Published Date: 7 August 2021

Construction and Validation of a Nomogram to Predict Overall Survival in Very Young Female Patients with Curatively Resected Breast Cancer

Li N, Feng LW, Li ZN, Wang J, Yang L

Cancer Management and Research 2021, 13:6181-6190

Published Date: 6 August 2021

Video-Assisted Thoracoscopic Day Surgery for Patients with Pulmonary Nodules: A Single-Center Clinical Experience of 200 Cases

Dong Y, Li J, Chang J, Song W, Wang Y, Wang Y, Che G

Cancer Management and Research 2021, 13:6169-6179

Published Date: 6 August 2021

Predictive Value of Preoperative Controlling Nutritional Status Score Combined with Fibrinogen–Albumin Ratio in Postoperative Local Recurrence-Free Survival of Patients with Retroperitoneal Liposarcoma

Xue GQ, Li CP, Lv A, Tian XY, Wu JH, Qiu H, Hao CY

Cancer Management and Research 2021, 13:6157-6167

Published Date: 6 August 2021

TNRC6C-AS1 Promotes Thyroid Cancer Progression by Upregulating LPAR5 via miR-513c-5p

Tong C, Wang C, Wang Y, Xiao X

Cancer Management and Research 2021, 13:6141-6155

Published Date: 6 August 2021

A New Index AGR-PLR Score (APS) for Patients with Esophageal Squamous Cell Carcinoma Undergoing Radical Esophagectomy

Yao Y, Cai C, Sun F, Gong W

Cancer Management and Research 2021, 13:6129-6139

Published Date: 5 August 2021

The Co-Expression of Melanoma-Antigen Family a Proteins and New York Esophageal Squamous Cell Carcinoma-1 in Breast Cancer: A Pilot Study

Wang YX, Li FL, Du LX, Liu JF, Huo LG, Li SQ, Tian B

Cancer Management and Research 2021, 13:6123-6128

Published Date: 4 August 2021

Improvement of outcomes of an escalated high‐dose methotrexate-based regimen for patients with newly diagnosed primary central nervous system lymphoma: a real-world cohort study

Li Q, Ma J, Ma Y, Lin Z, Kang H, Chen B

Cancer Management and Research 2021, 13:6115-6122

Published Date: 4 August 2021

KLF7 Promotes Gastric Carcinogenesis Through Regulation of ANTXR1 [Corrigendum]

Li Y, Wang Q, Wang D, Fu W

Cancer Management and Research 2021, 13:6113-6114

Published Date: 4 August 2021

Anlotinib Combined with Cranial Radiotherapy for Non-Small Cell Lung Cancer Patients with Brain Metastasis: A Retrospectively, Control Study

He Z, Liu J, Ma Y, Jiang H, Cui Z, Wang G, Wu Y, Liu J, Cai X, Qian J, Huang J, Zhang H, Li H

Cancer Management and Research 2021, 13:6101-6111

Published Date: 4 August 2021

Lateral Ventricular Meningiomas: Clinical Features, Radiological Findings and Long-Term Outcomes

Teng H, Liu Z, Yan O, He W, Jie D, Qie Y, Xu J

Cancer Management and Research 2021, 13:6089-6099

Published Date: 4 August 2021

CircTMCO3 Promotes Gastric Cancer Progression by Regulating miR-577/RAB14 Axis

Yu P, Wei K, Zhang T, Tan Z, Zhao H, Sun H

Cancer Management and Research 2021, 13:6079-6088

Published Date: 4 August 2021

The Role of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Predicting Treatment Response for Cervical Cancer Treated with Concurrent Chemoradiotherapy

Lu H, Wu Y, Liu X, Huang H, Jiang H, Zhu C, Man Y, Liu P, Li X, Chen Z, Long X, Pang Q, Deng S, Gu J

Cancer Management and Research 2021, 13:6065-6078

Published Date: 4 August 2021

A Serum Metabolomic Study Reveals Changes in Metabolites During the Treatment of Lung Cancer-Bearing Mice with Anlotinib

Pan X, Chen W, Nie M, Liu Y, Xiao Z, Zhang Y, Zhang W, Zou X

Cancer Management and Research 2021, 13:6055-6063

Published Date: 4 August 2021

The Antitumor Activity of CAR-T-PD1 Cells Enhanced by HPV16mE7-Pulsed and SOCS1-Silenced DCs in Cervical Cancer Models

Zheng J, Huang J, Ma W, Yang W, Hu B

Cancer Management and Research 2021, 13:6045-6053

Published Date: 4 August 2021

Propofol Suppresses Gastric Cancer Progression by Regulating circPDSS1/miR-1324/SOX4 Axis

Liu L, Dong T, Sheng J

Cancer Management and Research 2021, 13:6031-6043

Published Date: 3 August 2021

Accumulation of Regulatory T Cells in Triple Negative Breast Cancer Can Boost Immune Disruption

Zahran AM, El-Badawy O, Kamel LM, Rayan A, Rezk K, Abdel-Rahim MH

Cancer Management and Research 2021, 13:6019-6029

Published Date: 3 August 2021

Comprehensive Analysis of 5-Methylcytosine Profiles of Messenger RNA in Human High-Grade Serous Ovarian Cancer by MeRIP Sequencing

Meng L, Zhang Q, Huang X

Cancer Management and Research 2021, 13:6005-6018

Published Date: 3 August 2021

A Novel miRNA–mRNA Axis Involves in Regulating Transcriptional Disorders in Pancreatic Adenocarcinoma

Shang X, Shi LE, Taule D, Zhu ZZ

Cancer Management and Research 2021, 13:5989-6004

Published Date: 3 August 2021

Circ_0072995 Promotes Proliferation and Invasion via Regulating miR-1253/EIF4A3 Signaling in HCC

He Q, Tao L, Xu H, Xie X, Cheng S

Cancer Management and Research 2021, 13:5981-5987

Published Date: 3 August 2021

Prognostic Value of Combined CA19-9 with Aspartate Aminotransferase to Lymphocyte Ratio in Patients with Intrahepatic Cholangiocarcinoma After Hepatectomy

Qiu H, Liu C, Huang M, Shen S, Wang W

Cancer Management and Research 2021, 13:5969-5980

Published Date: 3 August 2021

LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis

Cen X, Huang Y, Lu Z, Shao W, Zhuo C, Bao C, Feng S, Wei C, Tang X, Cen L, Guo W, Tian X, Tang Q, Huang X

Cancer Management and Research 2021, 13:5957-5968

Published Date: 3 August 2021

Referral for “Neoadjuvant Chemotherapy” for Muscle-Invasive Bladder Cancer to a Multidisciplinary Board: Patterns, Management and Outcomes

Dellis A, Zakopoulou R, Kougioumtzopoulou A, Tzannis K, Koutsoukos K, Fragkoulis C, Kostouros E, Papatsoris A, Varkarakis I, Stravodimos K, Boutati E, Pagoni S, Seferlis M, Chrisofos M, Kouloulias V, Ntoumas K, Deliveliotis C, Constantinides C, Dimopoulos MA, Bamias A

Cancer Management and Research 2021, 13:5941-5955

Published Date: 30 July 2021

Intrapulmonic Cavity or Necrosis on Baseline CT Scan Serves as an Efficacy Predictor of Anti-PD-(L)1 Inhibitor in Advanced Lung Squamous Cell Carcinoma

Lu T, Zhang L, Chen M, Zheng X, Jiang K, Zheng X, Li C, Xiao W, Miao Q, Yang S, Lin G

Cancer Management and Research 2021, 13:5931-5939

Published Date: 30 July 2021

The Relationship Between UBE2C and AGGF1 Overexpression and Tumor Angiogenesis in Non-Small Cell Lung Cancer

Wang Y, Shi F, Tao R, Wu J, Gu J, Yang R, Wu S

Cancer Management and Research 2021, 13:5919-5930

Published Date: 30 July 2021

Activation of FXR Suppresses Esophageal Squamous Cell Carcinoma Through Antagonizing ERK1/2 Signaling Pathway

Feng Q, Zhang H, Yao D, Zhang X, Chen WD, Wang YD

Cancer Management and Research 2021, 13:5907-5918

Published Date: 30 July 2021

Original Research

Delayed Breast Cancer Detection in an Asian Country (Taiwan) with Low COVID-19 Incidence

Chou CP, Lin HS

Cancer Management and Research 2021, 13:5899-5906

Published Date: 28 July 2021

Predictive Value of Pretreatment Peripheral Neutrophil-to-Lymphocyte Ratio for Response to Neoadjuvant Chemotherapy and Breast Cancer Prognosis

Li X, Tan Q, Li H, Yang X

Cancer Management and Research 2021, 13:5889-5898

Published Date: 28 July 2021

Review

Cancer Services During the COVID-19 Pandemic: Systematic Review of Patient’s and Caregiver’s Experiences

Dhada S, Stewart D, Cheema E, Hadi MA, Paudyal V

Cancer Management and Research 2021, 13:5875-5887

Published Date: 29 July 2021

Long Non-Coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis [Retraction]

Qu R, Hu C, Tang Y, Yu Q, Shi G

Cancer Management and Research 2021, 13:5873-5874

Published Date: 29 July 2021

miR-4284 Promotes Cell Proliferation, Migration, and Invasion in Non-Small Cell Lung Cancer Cells and is Associated with Postoperative Prognosis

Yang H, Zhang W, Luan Q, Liu Y

Cancer Management and Research 2021, 13:5865-5872

Published Date: 28 July 2021

Interpectoral Lymph Node Dissection Can Be Spared in pN0/N1 Invasive Breast Cancer Undergoing Modified Radical Mastectomy: Single-Institution Experience from Mainland China

Yan Y, Jiang L, Fang J, Dai Y, Chenyu X, Ding J

Cancer Management and Research 2021, 13:5855-5863

Published Date: 27 July 2021

Clinical Outcomes and Prognostic Factors of Salvage Treatment for Local Lymph Node Recurrence After Radical Resection of Oesophageal Carcinoma

Gu L, Liu Y, Ye H, Gao F, Yin X, Zhao Y, Tian Y

Cancer Management and Research 2021, 13:5845-5853

Published Date: 23 July 2021

Risk Factors and Their Diagnostic Values for Ocular Metastases in Gastric Adenocarcinoma

Chen Y, Yang YC, Tang LY, Ge QM, Shi WQ, Su T, Shu HY, Pan YC, Liang RB, Li QY, Shao Y

Cancer Management and Research 2021, 13:5835-5843

Published Date: 23 July 2021

Astragalus IV Undermines Multi-Drug Resistance and Glycolysis of MDA-MB-231/ADR Cell Line by Depressing hsa_circ_0001982-miR-206/miR-613 Axis

Li H, Xia Z, Liu L, Pan G, Ding J, Liu J, Kang J, Li J, Jiang D, Liu W

Cancer Management and Research 2021, 13:5821-5833

Published Date: 22 July 2021

The Role and Application of Salivary Exosomes in Malignant Neoplasms

Deng Y, Cao Y, Wang L, Ye D

Cancer Management and Research 2021, 13:5813-5820

Published Date: 22 July 2021

Effect of Tumor Location on the Risk of Bilateral Central Lymph Node Metastasis in Unilateral 1-4 cm Papillary Thyroid Carcinoma

Liu N, Chen B, Li L, Zeng Q, Sheng L, Zhang B, Lv B

Cancer Management and Research 2021, 13:5803-5812

Published Date: 20 July 2021

Original Research

Performance of Plasma HSP90α, Serum EBV VCA IgA Antibody and Plasma EBV DNA for the Diagnosis and Prognosis Prediction of Nasopharyngeal Carcinoma

Ye Q, Guo J, Chen Y, Cui Z, Chen Y

Cancer Management and Research 2021, 13:5793-5802

Published Date: 20 July 2021

Gastric Cancer Screening Methods: A Comparative Study of Two Scoring Methods

Zhang W, Li Z, Akram MS, Rehman MF, Khan NH, Hu D, Mustaqeem M, Zeng YY, Kanwal F

Cancer Management and Research 2021, 13:5785-5791

Published Date: 20 July 2021

Human Polycomb Protein 2 (hPC2) as a Novel Independent Prognostic Marker in Nasopharyngeal Carcinoma

Wu M, Yang L, Hou X, Wang Z, Zhang J

Cancer Management and Research 2021, 13:5775-5784

Published Date: 20 July 2021

The Biological Function of TUSC7/miR-1224-3p Axis in Triple-Negative Breast Cancer

Zheng BH, He ZX, Zhang J, Ma JJ, Zhang HW, Zhu W, Shao ZM, Ni XJ

Cancer Management and Research 2021, 13:5763-5774

Published Date: 17 July 2021

Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma [Retraction]

Niu HT, Liu Y, Wang YZ, Tian Y, Yang M, Jiang HS

Cancer Management and Research 2021, 13:5761-5762

Published Date: 19 July 2021

The Maturation of Tumor Suppressor miR-497 in Hepatocellular Carcinoma is Inhibited by Oncogenic circRNA SCARB1

Zhu S, Cao S, Yang W, Che J, Li D, Pei R, Ding Y

Cancer Management and Research 2021, 13:5751-5759

Published Date: 16 July 2021

Key Candidate Genes – VSIG2 of Colon Cancer Identified by Weighted Gene Co-Expression Network Analysis

Cui Z, Li Y, He S, Wen F, Xu X, Lu L, Wu S

Cancer Management and Research 2021, 13:5739-5750

Published Date: 15 July 2021

Assessment of Potential Prognostic Value of Peroxiredoxin 1 in Oral Squamous Cell Carcinoma

Shen Y, Xu H, Li L, Lu Y, Zhang M, Huang X, Tang X

Cancer Management and Research 2021, 13:5725-5737

Published Date: 15 July 2021

The Role and Mechanism of S1PR5 in Colon Cancer [Retraction]

Zhou H, Yin X, Bai F, Liu W, Jiang S, Zhao J

Cancer Management and Research 2021, 13:5723-5724

Published Date: 15 July 2021

Weight Loss Improves Pregnancy and Livebirth Outcomes in Young Women with Early-Stage Endometrial Cancer and Atypical Hyperplasia

Zhang Y, Li D, Yan Q, Song X, Tian W, Wang Y, Teng F, Wei L, Wang J, Zhang H, Xue F

Cancer Management and Research 2021, 13:5711-5722

Published Date: 14 July 2021

Real-World Experience of Talimogene Laherparepvec (T-VEC) in Old and Oldest-Old Patients with Melanoma: A Retrospective Single Center Study

Kleemann J, Jäger M, Valesky E, Kippenberger S, Kaufmann R, Meissner M

Cancer Management and Research 2021, 13:5699-5709

Published Date: 15 July 2021

Identification of a Prognostic Index Based on a Metabolic-Genomic Landscape Analysis of Hepatocellular Carcinoma (HCC)

Yang X, Liu Q, Zou J, Li YK, Xie X

Cancer Management and Research 2021, 13:5683-5698

Published Date: 15 July 2021

LINC01224/ZNF91 Promote Stem Cell-Like Properties and Drive Radioresistance in Non-Small Cell Lung Cancer

Fu W, Zhao J, Hu W, Dai L, Jiang Z, Zhong S, Deng B, Huang Y, Wu W, Yin J

Cancer Management and Research 2021, 13:5671-5681

Published Date: 13 July 2021

Predicting Response to Total Neoadjuvant Treatment (TNT) in Locally Advanced Rectal Cancer Based on Multiparametric Magnetic Resonance Imaging: A Retrospective Study

Ouyang G, Yang X, Deng X, Meng W, Yu Y, Wu B, Jiang D, Shu P, Wang Z, Yao J, Wang X

Cancer Management and Research 2021, 13:5657-5669

Published Date: 13 July 2021

Neutrophil–Lymphocyte Ratio as a Predictive Factor of Growing Malignant Pulmonary Ground-glass Opacity

Xue W, Zhang X, Niu Z, Xin Z, Zhang H, Zhao Q, He J, Hu Z, Duan G

Cancer Management and Research 2021, 13:5651-5655

Published Date: 13 July 2021

Nomogram for the Prediction of Biochemical Incomplete Response in Papillary Thyroid Cancer Patients

Lim ST, Jeon YW, Gwak H, Bae JS, Suh YJ

Cancer Management and Research 2021, 13:5641-5650

Published Date: 13 July 2021

The Impact of Different Simulation Modalities on Target Volume Delineation in Breast-Conserving Radiotherapy

Jin M, Liu X, Ma J, Sun X, Zhen H, Shen J, Liu Z, Lian X, Miao Z, Hu K, Hou X, Zhang F

Cancer Management and Research 2021, 13:5633-5640

Published Date: 12 July 2021

Prognostic Values of Different Clinicopathological Factors and Predictive Models for Penile Carcinoma

Shao Y, Lia T, Wang Y, Wu K, Hu X, Liu Y, Feng S, Ren S, Yang Z, Xiong S, Yang W, Wei Q, Zeng H, Li X

Cancer Management and Research 2021, 13:5623-5632

Published Date: 12 July 2021

Original Research

Efficacy of Venetoclax Combined with Decitabine-Based Treatment for Heavily Pre-Treated Relapsed or Refractory AML Patients in a Real-World Setting

Tong J, Zhao N, Hu X, Yao W, Cheng Y, Zhou L, Liu H, Geng L, Sun Z, Zheng C

Cancer Management and Research 2021, 13:5613-5621

Published Date: 12 July 2021

Comprehensive Analysis of Peritoneal Metastasis Sequencing Data to Identify LINC00924 as a Prognostic Biomarker in Gastric Cancer

Fang Y, Huang S, Han L, Wang S, Xiong B

Cancer Management and Research 2021, 13:5599-5611

Published Date: 12 July 2021

LncRNA NEAT1 Acts as an miR-148b-3p Sponge to Regulate ROCK1 Inhibition of Retinoblastoma Growth

Lu H, Zhang Z, Lu Y, Xiu WW, Cui J

Cancer Management and Research 2021, 13:5587-5597

Published Date: 12 July 2021

Silencing of circHIPK3 Sensitizes Paclitaxel-Resistant Breast Cancer Cells to Chemotherapy by Regulating HK2 Through Targeting miR-1286

Ni J, Xi X, Xiao S, Xiao X

Cancer Management and Research 2021, 13:5573-5585

Published Date: 12 July 2021

Inhibition of Orthotopic Genital Cancer Induced by Subcutaneous Administration of Human Papillomavirus Peptide Vaccine with CpG Oligodeoxynucleotides as an Adjuvant in Mice

Wang H, Che Y, Yang Y, Suo J, Wang X

Cancer Management and Research 2021, 13:5559-5572

Published Date: 12 July 2021

RETRACTED ARTICLE: KLF7 Promotes Gastric Carcinogenesis Through Regulation of ANTXR1

Li Y, Wang Q, Wang D, Fu W

Cancer Management and Research 2021, 13:5547-5557

Published Date: 12 July 2021

MRPL13 Act as a Novel Therapeutic Target and Could Promote Cell Proliferation in Non-Small Cell Lung Cancer

Jing CQ, Fu R, Wang C, Li XR, Zhang W

Cancer Management and Research 2021, 13:5535-5545

Published Date: 12 July 2021

Effect of Regorafenib in Delaying Definitive Deterioration in Health-Related Quality of Life in Patients with Advanced Cancer of Three Different Tumor Types

Hofheinz RD, Bruix J, Demetri GD, Grothey A, Marian M, Bartsch J, Odom D

Cancer Management and Research 2021, 13:5523-5533

Published Date: 12 July 2021

Review

An Update on the Potential Roles of E2F Family Members in Colorectal Cancer

Xu Z, Qu H, Ren Y, Gong Z, Ri HJ, Chen X

Cancer Management and Research 2021, 13:5509-5521

Published Date: 9 July 2021

Role of Systemic Inflammatory Reaction in Female Genital Organ Malignancies – State of the Art

Mleko M, Pitynski K, Pluta E, Czerw A, Sygit K, Karakiewicz B, Banas T

Cancer Management and Research 2021, 13:5491-5508

Published Date: 9 July 2021

Dissecting Prognosis Modules and Biomarkers in Glioblastoma Based on Weighted Gene Co-Expression Network Analysis

Cao F, Fan Y, Yu Y, Yang G, Zhong H

Cancer Management and Research 2021, 13:5477-5489

Published Date: 8 July 2021

Can Prostate-Specific Antigen Density Be an Index to Distinguish Patients Who Can Omit Repeat Prostate Biopsy in Patients with Negative Magnetic Resonance Imaging?

Yu J, Boo Y, Kang M, Sung HH, Jeong BC, Seo S, Jeon SS, Lee H, Jeon HG

Cancer Management and Research 2021, 13:5467-5475

Published Date: 8 July 2021

Original Research

Efficacy and Safety Aiming at the Combined-Modality Therapy of External Beam Radiotherapy (40Gy) and Iodine-125 Seed Implantation for Locally Advanced NSCLC in the Elderly

Tian LJ, Liu HZ, Zhang Q, Geng DZ, Huo YQ, Xu SJ, Hao Y

Cancer Management and Research 2021, 13:5457-5466

Published Date: 8 July 2021

LncRNA HOXA-AS2 Promotes Tumor Progression by Suppressing miR-567 Expression in Oral Squamous Cell Carcinoma

Chen R, Wang X, Zhou S, Zeng Z

Cancer Management and Research 2021, 13:5443-5455

Published Date: 8 July 2021

The Repository for Caribbean Cancer Publications (ReCCaP): Database Development and Publication Trends 2004–2019

Badal K, Moore M, Thomas M

Cancer Management and Research 2021, 13:5433-5442

Published Date: 7 July 2021

Quantitative Analysis and Pathological Basis of Signal Intensity on T2-Weighted MR Images in Benign and Malignant Parotid Tumors

Wei P, Shao C, Tian M, Wu M, Wang H, Han Z, Hu H

Cancer Management and Research 2021, 13:5423-5431

Published Date: 7 July 2021

Impact of the Time Interval Between Primary Debulking Surgery and Start of Adjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer

Lin H, Chen WH, Wu CH, Ou YC, Chen YJ, Chen YY, Lin YH, Fu HC

Cancer Management and Research 2021, 13:5413-5422

Published Date: 6 July 2021

No Detection of Pseudocapsule of Tumor-Parenchyma Interface on Multidetector Computed Tomography (MDCT) Images: Clinical Significance and Histological Reflections in Renal Cell Carcinoma

Xi W, Tan Q, Hou Y, Hu X, Wang H, Liu L, Xia Y, Bai Q, Wang J, Zhou J, Guo J

Cancer Management and Research 2021, 13:5403-5411

Published Date: 6 July 2021

Efficacy of Drug-Eluting Beads Transarterial Chemoembolization Plus Apatinib Compared with Conventional Transarterial Chemoembolization Plus Apatinib in the Treatment of Unresectable Hepatocellular Carcinoma

Zhang W, Chen L, Cao Y, Sun B, Ren Y, Sun T, Zheng C

Cancer Management and Research 2021, 13:5391-5402

Published Date: 6 July 2021

Evaluation of Hybrid PET/MRI for Gross Tumor Volume (GTV) Delineation in Colorectal Cancer Liver Metastases Radiotherapy

Zhang YN, Lu X, Lu ZG, Fu LP, Zhao J, Xiang ZL

Cancer Management and Research 2021, 13:5383-5389

Published Date: 6 July 2021

A Comparison of Adverse Events Among Radiofrequency Ablation, Conventional Transarterial Chemoembolization (TACE) and Drug-Eluting Bead TACE in Treating Hepatocellular Carcinoma Patients

Cao G, Liu Y, Li L, Zhao X, Liu R, Liu J, Liu J, Cao H

Cancer Management and Research 2021, 13:5373-5382

Published Date: 5 July 2021

High-Expression of Cytoplasmic Poly (A) Binding Protein 1 (PABPC1) as a Prognostic Biomarker for Early-Stage Esophageal Squamous Cell Carcinoma

Pu J, Zhang T, Zhang D, He K, Chen Y, Sun X, Long W

Cancer Management and Research 2021, 13:5361-5372

Published Date: 5 July 2021

Preablative Stimulated Thyroglobulin and Thyroglobulin Reduction Index as Decision-Making Markers for Second Radioactive Iodine Therapy in Patients with Structural Incomplete Response

Wang L, Yun C, Huang F, Xiao J, Ju Y, Cheng F, Zhang W, Jia H

Cancer Management and Research 2021, 13:5351-5360

Published Date: 5 July 2021

Circular RNA Circ_0003221 Promotes Cervical Cancer Progression by Regulating miR-758-3p/CPEB4 Axis

Xie H, Wang J, Wang B

Cancer Management and Research 2021, 13:5337-5350

Published Date: 5 July 2021

Review

Regulatory Mechanisms of LncRNAs in Cancer Glycolysis: Facts and Perspectives

Huang P, Zhu S, Liang X, Zhang Q, Luo X, Liu C, Song L

Cancer Management and Research 2021, 13:5317-5336

Published Date: 5 July 2021

Prognostic Characteristics of Operated Breast Cancer Patients with Second Primary Lung Cancer: A Retrospective Study

Wang Y, Li J, Chang S, Dong Y, Che G

Cancer Management and Research 2021, 13:5309-5316

Published Date: 5 July 2021

The Clinical Value of Computed Tomography (CT)-Guided 125I Brachytherapy for Locally Advanced Non-Small Cell Lung Cancer After Progression of Concurrent Radiochemotherapy

Xiang Z, Zhong Z, Mu L, Li G, Zhou C, Wang H, Huang M

Cancer Management and Research 2021, 13:5297-5307

Published Date: 5 July 2021

The Assessment of Prostate Cancer Aggressiveness Using a Combination of Quantitative Diffusion-Weighted Imaging and Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Zhu G, Luo J, Ouyang Z, Cheng Z, Deng Y, Guan Y, Du G, Zhao F

Cancer Management and Research 2021, 13:5287-5295

Published Date: 2 July 2021

Current Progress in Investigating Mature T- and NK-Cell Lymphoma Gene Aberrations by Next-Generation Sequencing (NGS)

Zhu L, Xie S, Yang C, Hua N, Wu Y, Wang L, Ni W, Tong X, Fei M, Wang S

Cancer Management and Research 2021, 13:5275-5286

Published Date: 2 July 2021

Preoperative Prognostic Nutrition Index as a Prognostic Indicator of Survival in Elderly Patients Undergoing Gastric Cancer Surgery

Zhang X, Fang H, Zeng Z, Zhang K, Lin Z, Deng G, Deng W, Guan L, Wei X, Li X, Jiang L, Xu L

Cancer Management and Research 2021, 13:5263-5273

Published Date: 2 July 2021

Development and External Validation of Safe Discharge Criteria After Radical Gastrectomy

Yu D, Wu X, Li X, Liu X, Jiang K, Zhao Q, Nie H

Cancer Management and Research 2021, 13:5251-5261

Published Date: 1 July 2021

Review

Effective Strategies to Predict Survival of Colorectal Peritoneal Metastases Patients Eligible for Cytoreductive Surgery and HIPEC

Simkens GA, Wintjens AGWE, Rovers KP, Nienhuijs SW, de Hingh IH

Cancer Management and Research 2021, 13:5239-5249

Published Date: 1 July 2021

Review

Potential Prospect of CDK4/6 Inhibitors in Triple-Negative Breast Cancer

Hu Y, Gao J, Wang M, Li M

Cancer Management and Research 2021, 13:5223-5237

Published Date: 1 July 2021

Hsa_circRNA_000543 Predicts Poor Prognosis and Promotes Cervical Cancer Cell Progression Through Regulating miR-567/ZNF268 Axis

Yao Z, Shu L, Yi Y, Qiao L

Cancer Management and Research 2021, 13:5211-5222

Published Date: 30 June 2021

Expert Opinion

What to Do and What Not to Do in the Management of Cancer Pain: A Physician Survey and Expert Recommendations

Bossi P, Antonuzzo A, Armento G, Consoli F, Giuliani J, Giusti R, Lucchesi M, Mirabile A, Palermo L, Scagliarini S

Cancer Management and Research 2021, 13:5203-5210

Published Date: 30 June 2021

TRIM66 Overexpression Promotes Glioma Progression and Regulates Glucose Uptake Through cMyc/GLUT3 Signaling

Song Y, Meng L, Yu J, Cao Z, Sun J, Zhao H

Cancer Management and Research 2021, 13:5187-5201

Published Date: 30 June 2021

Hypomethylation-Mediated AGR2 Overexpression Facilitates Cell Proliferation, Migration, and Invasion of Lung Adenocarcinoma

He J, Fu Y, Hu J, Chen J, Lou G

Cancer Management and Research 2021, 13:5177-5185

Published Date: 30 June 2021

LncRNA AFAP1-AS1 Modulates the Proliferation and Invasion of Gastric Cancer Cells by Regulating AFAP1 via miR-205-5p

Dang Y, Ouyang X, Ren W, Wang L, Huang Q

Cancer Management and Research 2021, 13:5163-5175

Published Date: 30 June 2021

Circ_0105346 Knockdown Inhibits Osteosarcoma Development via Regulating miR-1182/WNT7B Axis [Retraction]

Liu J, Li X, Yue L, Lv H

Cancer Management and Research 2021, 13:5161-5162

Published Date: 30 June 2021

Cardiotoxicity and Cardiac Monitoring Among Anthracycline-Treated Cancer Patients: A Retrospective Cohort Study

Alkofide H, Alnaim L, Alorf N, Alessa W, Bawazeer G

Cancer Management and Research 2021, 13:5149-5159

Published Date: 29 June 2021

Comprehensive Bioinformatics Analysis of mRNA Expression Profiles and Identification of a miRNA–mRNA Network Associated with the Pathogenesis of Low-Grade Gliomas

Wang M, Cui Y, Cai Y, Jiang Y, Peng Y

Cancer Management and Research 2021, 13:5135-5147

Published Date: 29 June 2021

Risk Factors of Delayed Recovery of Gastrointestinal Function After Ileostomy Reversal for Rectal Cancer Patients

Chu L, Wang H, Qiu S, Shao B, Huang J, Qin Q, He Y, Xue J, Li X, Huang X, Huang R

Cancer Management and Research 2021, 13:5127-5133

Published Date: 29 June 2021

Prognostic Score Model Based on Ten Differentially Methylated Genes for Predicting Clinical Outcomes in Patients with Adenocarcinoma of the Colon

Sun G, Duan H, Xing Y, Zhang D

Cancer Management and Research 2021, 13:5113-5125

Published Date: 28 June 2021

Genomic Analysis Revealed Mutational Traits Associated with Clinical Outcomes in Osteosarcoma

Chi X, Ji T, Li J, Xu J, Tang X, Xie L, Meng F, Guo W

Cancer Management and Research 2021, 13:5101-5111

Published Date: 28 June 2021

Long Noncoding RNA AATBC Promotes the Proliferation and Migration of Prostate Cancer Cell Through miR-1245b-5p/CASK Axis

Zhang W, Liu Q, Zhao J, Wang T, Wang J

Cancer Management and Research 2021, 13:5091-5100

Published Date: 28 June 2021

CircASXL1 Knockdown Restrains Hypoxia-Induced DDP Resistance and NSCLC Progression by Sponging miR-206

Yu L, Li J, Peng B, Cai P, Zhao B, Chen Y, Zhu H

Cancer Management and Research 2021, 13:5077-5089

Published Date: 28 June 2021

A miR-212-3p/SLC6A1 Regulatory Sub-Network for the Prognosis of Hepatocellular Carcinoma

Zhang DD, Wang WE, Ma YS, Shi Y, Yin J, Liu JB, Yang XL, Xin R, Fu D, Zhang WJ

Cancer Management and Research 2021, 13:5063-5075

Published Date: 28 June 2021

Original Research

Value of Machine Learning with Multiphases CE-MRI Radiomics for Early Prediction of Pathological Complete Response to Neoadjuvant Therapy in HER2-Positive Invasive Breast Cancer

Li Q, Xiao Q, Li J, Wang Z, Wang H, Gu Y

Cancer Management and Research 2021, 13:5053-5062

Published Date: 28 June 2021

The Risk Assessment and Clinical Research of Bile Duct Injury After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma

Xu H, Yu X, Hu J

Cancer Management and Research 2021, 13:5039-5052

Published Date: 28 June 2021

CircCSNK1G1 Contributes to the Tumorigenesis of Gastric Cancer by Sponging miR-758 and Regulating ZNF217 Expression

Qiang F, Li J

Cancer Management and Research 2021, 13:5027-5038

Published Date: 28 June 2021

High Endothelin Receptor Type A Expression as an Independent Prognostic Biomarker and Correlated with Immune Infiltrates in Stomach Adenocarcinoma

Yan Y, Nie K, Zheng J, Jiang X, Huang Y, Zheng Z, Wen Y, Li P

Cancer Management and Research 2021, 13:5013-5026

Published Date: 28 June 2021

Original Research

Preoperative Blood Inflammatory Markers for the Differentiation of Uterine Leiomyosarcoma from Leiomyoma

Suh DS, Song YJ, Roh HJ, Lee SH, Jeong DH, Lee TH, Choi KU, Kim KH

Cancer Management and Research 2021, 13:5001-5011

Published Date: 24 June 2021

Review

Understanding and Monitoring Chronic Myeloid Leukemia Blast Crisis: How to Better Manage Patients

Wang L, Li L, Chen R, Huang X, Ye X

Cancer Management and Research 2021, 13:4987-5000

Published Date: 23 June 2021

Adenosquamous Carcinoma of the Uterine Cervix – Impact of Histology on Clinical Management

Yordanov A, Kostov S, Slavchev S, Strashilov S, Konsoulova A, Calleja-Agius J, Di Fiore R, Suleiman S, Kubelac P, Vlad C, Achimas-Cadariu P, Vasileva-Slaveva M

Cancer Management and Research 2021, 13:4979-4986

Published Date: 23 June 2021

LncRNA SNHG17 Contributes to the Progression of Cervical Cancer by Targeting microRNA-375-3p

Cao S, Li H, Li L

Cancer Management and Research 2021, 13:4969-4978

Published Date: 23 June 2021

Analysis of Mono-ADP-Ribosylation Levels in Human Colorectal Cancer [Corrigendum]

Wang CL, Tang Y, Li M, Xiao M, Li QS, Yang L, Li X, Yin L, Wang YL

Cancer Management and Research 2021, 13:4967-4968

Published Date: 23 June 2021

Dose–Effect Relationship Between Gastric Cancer and Common Digestive Tract Symptoms and Diagnoses in Anhui, China

Tang M, Shen X, Chai J, Cheng J, Wang D

Cancer Management and Research 2021, 13:4955-4966

Published Date: 22 June 2021

Perioperative Transfusion is Related to the Length of Hospital Stays in Primary Liver Cancer Patients

Qi Q, Qian X, Zhu X, Cai J, Xia R, Zhang Q

Cancer Management and Research 2021, 13:4947-4954

Published Date: 21 June 2021

Prognostic Significance of Serum PD-L1 Level in Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Combination Cytotoxic Chemotherapy

Fu R, Jing CQ, Li XR, Tan ZF, Li HJ

Cancer Management and Research 2021, 13:4935-4946

Published Date: 21 June 2021

Elevated Pretreatment Fibrinogen-to-Lymphocyte Percentage Ratio Predict Tumor Staging and Poor Survival in Non-Small Cell Lung Cancer Patients with Chemotherapy or Surgery Combined with Chemotherapy

Liu M, Yang J, Wan L, Zhao R

Cancer Management and Research 2021, 13:4921-4933

Published Date: 21 June 2021

Identification of ZNF704 as a Novel Oncogene and an Independent Prognostic Marker in Chondrosarcoma

Chen C, Zhou H, Zhang X, Liu Z, Ma X

Cancer Management and Research 2021, 13:4911-4919

Published Date: 21 June 2021

Original Research

The Value of Cervical Node Features in Predicting Long-Term Survival of Nasopharyngeal Carcinoma in the Intensity-Modulated Radiotherapy Era

Tian YM, Zeng L, Lan YH, Yuan X, Bai L, Han F

Cancer Management and Research 2021, 13:4899-4909

Published Date: 21 June 2021

Original Research

CA19-9 Level to Serum γ-Glutamyltransferase as a Potential Prognostic Biomarker in Patients with Pancreatic Head Carcinoma

Lyu SC, Wang J, Huang M, Wang HX, Zhou L, He Q, Lang R

Cancer Management and Research 2021, 13:4887-4898

Published Date: 21 June 2021

Original Research

Improvement of Diagnostic Accuracy for Pancreatic Cancer with Serum Lactate Dehydrogenase

Wang X, Wang C, Zhang H

Cancer Management and Research 2021, 13:4879-4886

Published Date: 21 June 2021

Topical Application of Pseudomonas aeruginosa-Mannose Sensitive Hemagglutinin (PA-MSHA) for Refractory Lymphatic Leakage Following Lymphadenectomy in Patients with Gynecological Malignancies

Zhou R, Xu J, He J, Gong Y, Wang H, Linghu H

Cancer Management and Research 2021, 13:4873-4878

Published Date: 21 June 2021

Original Research

Case Analysis of 14 Children with Malignant Rhabdoid Tumor of the Kidney

Li J, Zhang W, Hu H, Zhang Y, Wang Y, Gu H, Huang D

Cancer Management and Research 2021, 13:4865-4872

Published Date: 21 June 2021

The Presence of Genomic Instability in Cerebrospinal Fluid in Patients with Meningeal Metastasis

Wang P, Zhang H, Chen P, Sun Z, Zhang Z, Yin Q, Sun H, Yu J

Cancer Management and Research 2021, 13:4853-4863

Published Date: 21 June 2021

Silencing UHRF1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma by Inhibiting the PI3K/Akt/mTOR Signaling Pathway

Hui B, Pan S, Che S, Sun Y, Yan Y, Guo J, Gong T, Ren J, Zhang X

Cancer Management and Research 2021, 13:4841-4852

Published Date: 21 June 2021

Downregulation of MicroRNA-130a Inhibits Oral Squamous Cell Carcinoma Proliferation and Metastasis via the Hippo-YAP Pathway

Peng Y, Hu S, Zhang K, Wang Y, Rouzi M, Zhou D, Yang R

Cancer Management and Research 2021, 13:4829-4840

Published Date: 17 June 2021

Influence of CDK5 Regulatory Subunit-Associated Protein 1-Like 1 Expression on the Survival of Patients with Non-Metastatic Nasopharyngeal Carcinoma

Li Z, Zhao Y

Cancer Management and Research 2021, 13:4821-4828

Published Date: 17 June 2021

Machine Learning for the Prediction of Lymph Nodes Micrometastasis in Patients with Non-Small Cell Lung Cancer: A Comparative Analysis of Two Practical Prediction Models for Gross Target Volume Delineation

Hu S, Luo M, Li Y

Cancer Management and Research 2021, 13:4811-4820

Published Date: 17 June 2021

The Guiding Significance of the Number of Positive Sentinel Lymph Nodes in Frozen Section for Intraoperative Axillary Dissection in Early Breast Cancer

Liang C, Li L, Zhu M, Hu J, Yu Y

Cancer Management and Research 2021, 13:4803-4810

Published Date: 17 June 2021

Klotho Inhibits Proliferation in a RET Fusion Model of Papillary Thyroid Cancer by Regulating the Wnt/β-Catenin Pathway

Wu Q, Jiang L, Wu J, Dong H, Zhao Y

Cancer Management and Research 2021, 13:4791-4802

Published Date: 17 June 2021

Risk Factors for Recurrence of Radically Resected Mucinous Colorectal Adenocarcinoma

Huang Q, Zou MH, Wei JC, Jiang Y, Chen ZP, Wang Q, Li WL, Cao J

Cancer Management and Research 2021, 13:4777-4790

Published Date: 17 June 2021

A Retrospective Study of Biliary Drainage Strategies for Patients with Malignant Hilar Biliary Strictures

Liang XY, Li W, Liu F, Kang XD

Cancer Management and Research 2021, 13:4767-4776

Published Date: 17 June 2021

microRNA-944 Inhibits the Malignancy of Hepatocellular Carcinoma by Directly Targeting IGF-1R and Deactivating the PI3K/Akt Signaling Pathway [Retraction]

Lv L, Wang X, Ma T

Cancer Management and Research 2021, 13:4765-4766

Published Date: 16 June 2021

Carbon Ion and Proton Beam Irradiation of a Normal Human TK6 Lymphoblastoid Cell Line Within a Magnetic Field of 1.0 Tesla [Corrigendum]

Yudhistiara B, Weber KJ, Huber PE, Ruehle A, Brons S, Haering P, Debus J, Hauswald H

Cancer Management and Research 2021, 13:4763-4764

Published Date: 15 June 2021

Nomogram to Predict Distant Metastasis Probability for Pathological Complete Response Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy

Jiang T, Liu S, Wu X, Liu X, Li W, Yang S, Cai P, Xi S, Zeng Z, Gao Y, Chen G, Xiao W

Cancer Management and Research 2021, 13:4751-4761

Published Date: 15 June 2021

Circular RNA 0014715 Facilitates Cell Proliferation and Inhibits Apoptosis in Esophageal Squamous Cell Carcinoma

Zhang H, Ju L, Hu P, Ye J, Yang C, Huang J

Cancer Management and Research 2021, 13:4735-4749

Published Date: 15 June 2021

Original Research

Sleep Quality and Related Factors in Patients with Breast Cancer: A Cross-Sectional Study in Taiwan

Weng YP, Hong RM, Chen VCH, Tsai CJ, Yeh DC, Fang YH

Cancer Management and Research 2021, 13:4725-4733

Published Date: 14 June 2021

High SQLE Expression and Gene Amplification Correlates with Poor Prognosis in Head and Neck Squamous Cell Carcinoma

Liu Y, Fang L, Liu W

Cancer Management and Research 2021, 13:4709-4723

Published Date: 14 June 2021

Original Research

Predicting Survival for Patients with Malignant Pleural Effusion: Development of the CONCH Prognostic Model

Zhang X, Yi FS, Shi HZ

Cancer Management and Research 2021, 13:4699-4707

Published Date: 14 June 2021

Original Research

Clinical Analysis of the Short-Term Outcome of Papillary Thyroid Micro Carcinoma After 131I Treatment

Cao J, Yun C, Zhu X, Li X, Sun Y, Zhang W

Cancer Management and Research 2021, 13:4691-4698

Published Date: 14 June 2021

HSPA4 Knockdown Retarded Progression and Development of Colorectal Cancer

Zhang M, Dai W, Li Z, Tang L, Chen J, Chen C

Cancer Management and Research 2021, 13:4679-4690

Published Date: 14 June 2021

The Combination of Neoadjuvant Therapy and Surgical Resection: A Safe and Effective Treatment for Rectal Gastrointestinal Stromal Tumors

Liu Y, Chang W, Tang W, Wei Y, Liu T, Chen Y, Ji M, Liang F, Ren L, Xu J

Cancer Management and Research 2021, 13:4671-4678

Published Date: 14 June 2021

“High Tumor Burden” in Metastatic Non-Small Cell Lung Cancer: Defining the Concept

Higuera Gómez O, Moreno Paul A, Ortega Granados AL, Ros Martínez S, Pérez Parente D, Ruiz Gracia P, Sáenz Cuervo-Arango L, Vilà L

Cancer Management and Research 2021, 13:4665-4670

Published Date: 14 June 2021

Original Research

Diagnostic Value of Preoperative CA125, LDH and HE4 for Leiomyosarcoma of the Female Reproductive System

Zhang F, Liu Y, Quan Q, Meng Y, Mu X

Cancer Management and Research 2021, 13:4657-4664

Published Date: 14 June 2021

Elevated Platelet Distribution Width Predicts Poor Prognosis in Gallbladder Carcinoma

Liu F, Hu HJ, Regmi P, Jin YW, Ma WJ, Wang JK, Zou RQ, Li FY

Cancer Management and Research 2021, 13:4647-4655

Published Date: 10 June 2021

Original Research

Carcinosarcomas of the Uterus: Prognostic Factors and Impact of Adjuvant Treatment

Beckmann K, Selva-Nayagam S, Olver I, Miller C, Buckley ES, Powell K, Buranyi-Trevarton D, Gowda R, Roder D, Oehler MK

Cancer Management and Research 2021, 13:4633-4645

Published Date: 10 June 2021

Value of Nomogram Incorporated Preoperative Tumor Volume and the Number of Postoperative Pathologically Lymph Node Metastasis Regions on Predicting the Prognosis of Thoracic Esophageal Squamous Cell Carcinoma

Guo XW, Zhang H, Xu L, Zhou S, Zhou J, Liu Y, Ji S

Cancer Management and Research 2021, 13:4619-4631

Published Date: 10 June 2021

Original Research

Deep Learning-Based Multi-Class Classification of Breast Digital Pathology Images

Mi W, Li J, Guo Y, Ren X, Liang Z, Zhang T, Zou H

Cancer Management and Research 2021, 13:4605-4617

Published Date: 10 June 2021

Patterns and Prevalence of BRCA1 and BRCA2 Germline Mutations Among Patients with Triple-Negative Breast Cancer: Regional Perspectives

Abdel-Razeq H, Tamimi F, Abujamous L, Edaily S, Abunasser M, Bater R, Salama O

Cancer Management and Research 2021, 13:4597-4604

Published Date: 9 June 2021

CircRNA CircRIMS is Overexpressed in Esophageal Squamous Cell Carcinoma and Downregulate miR-613 Through Methylation to Increase Cell Proliferation

Wan H, Yuan B, Jiang K, Wei J, Feng X, Sun B, Wang F

Cancer Management and Research 2021, 13:4587-4595

Published Date: 9 June 2021

Associations of Estrogen Receptor, Progesterone Receptor, Human Epidemic Growth Factor Receptor-2 and Ki-67 with Ultrasound Signs and Prognosis of Breast Cancer Patients

Zhao X, Yang X, Fu L, Yu K

Cancer Management and Research 2021, 13:4579-4586

Published Date: 9 June 2021

Original Research

Detection and Clinical Value of Circulating Tumor Cells as an Assisted Prognostic Marker in Colorectal Cancer Patients

Pan RJ, Hong HJ, Sun J, Yu CR, Liu HS, Li PY, Zheng MH

Cancer Management and Research 2021, 13:4567-4578

Published Date: 8 June 2021

Dietary Pattern at 18-Month Post-Diagnosis and Outcomes of Breast Cancer Among Chinese Women with Early-Stage Breast Cancer

Lei Y, Ho SC, Kwok C, Cheng AC, Cheung KL, Lee R, Yeo W

Cancer Management and Research 2021, 13:4553-4565

Published Date: 8 June 2021

Efficacy and Treatment Strategies in Advanced Cancers with Liver Metastasis Receiving Atezolizumab Therapy

Yin WJ, Ma SC, Dong ZY, Xu M, Mao W

Cancer Management and Research 2021, 13:4541-4551

Published Date: 8 June 2021

Original Research

Retrospective Analysis of Clinicopathological Features and Prognosis of Gynecological Small-Cell Carcinoma

Pang L, Yang H, Ning Y, Zheng C

Cancer Management and Research 2021, 13:4529-4540

Published Date: 8 June 2021

Prognostic Alternative Splicing Signatures in Esophageal Carcinoma

Dlamini Z, Hull R, Mbatha SZ, Alaouna M, Qiao YL, Yu H, Chatziioannou A

Cancer Management and Research 2021, 13:4509-4527

Published Date: 4 June 2021

The Preliminary Study for Postoperative Radiotherapy Survival Associated with RUNX3 and TLR9 Expression in Lung Cancer

Gao C, Qiao T, Yuan S, Zhuang X

Cancer Management and Research 2021, 13:4497-4507

Published Date: 4 June 2021

Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway

Liu X, Guo Q, Jing F, Zhou C, Xiu T, Shi Y, Jing F

Cancer Management and Research 2021, 13:4483-4495

Published Date: 4 June 2021

Factors Associated with Malignancy in Patients with Maximal Thyroid Nodules ≥2 Cm

Dong S, Pan J, Shen YB, Zhu LX, Xia Q, Xie XJ, Wu YJ

Cancer Management and Research 2021, 13:4473-4482

Published Date: 4 June 2021

Tumor-to-Gland Volume Ratio versus Tumor-to-Breast Ratio as Measured on CBBCT: Possible Predictors of Breast-Conserving Surgery

Li J, Zhong G, Wang K, Kang W, Wei W

Cancer Management and Research 2021, 13:4463-4471

Published Date: 3 June 2021

Prolyl-4-Hydroxylase α Subunit 2 as a Novel Potential Biomarker for Predicting the Prognosis of Epithelial Ovarian Carcinoma

Zhang H, Zhao W

Cancer Management and Research 2021, 13:4455-4462

Published Date: 3 June 2021

Multiple Pulmonary Metastases of Recurrent Giant Cell Tumor of Bone with Expression of VEGFR-2 Successfully Controlled by Denosumab and Apatinib: A Case Report and Literature Review

Gong T, Luo Y, Wang Y, Zheng C, Fang J, Min L, Zhou Y, Tu C

Cancer Management and Research 2021, 13:4447-4454

Published Date: 3 June 2021

CircPRDM2 Contributes to Doxorubicin Resistance of Osteosarcoma by Elevating EZH2 via Sponging miR-760

Yuan J, Liu Y, Zhang Q, Ren Z, Li G, Tian R

Cancer Management and Research 2021, 13:4433-4445

Published Date: 2 June 2021

CD44+ Circulating Tumor Endothelial Cells Indicate Poor Prognosis in Pancreatic Ductal Adenocarcinoma After Radical Surgery: A Pilot Study

Xing C, Li Y, Ding C, Wang S, Zhang H, Chen L, Li P, Dai M

Cancer Management and Research 2021, 13:4417-4431

Published Date: 1 June 2021

Development and Validation of a Prognostic Nomogram for Postoperative Recurrence-Free Survival of Ameloblastoma

Yang YC, Wang JJ, Huang Y, Cai WX, Tao Q

Cancer Management and Research 2021, 13:4403-4416

Published Date: 1 June 2021

LINC-PINT Inhibited Malignant Progression of Bladder Cancer by Targeting miR-155-5p

Han X, Liu J, Liu Y, Mou L, Li C

Cancer Management and Research 2021, 13:4393-4401

Published Date: 1 June 2021

Enhanced Recovery After Surgery Impact on the Systemic Inflammatory Response of Patients Following Gynecological Oncology Surgery: A Prospective Randomized Study

Peng J, Dong R, Jiao J, Liu M, Zhang X, Bu H, Dong P, Zhao S, Xing N, Feng S, Yang X, Kong B

Cancer Management and Research 2021, 13:4383-4392

Published Date: 1 June 2021

Original Research

Survival of Patients with Lung Cancer in the Setting of Liver Cirrhosis: A Multicenter Propensity Score Matching Study

Lu MS, Lu HI, Chen TP, Chang CC, Yang TM, Chen MF

Cancer Management and Research 2021, 13:4373-4381

Published Date: 1 June 2021

Grape Seed Proanthocyanidins (GSPs) Inhibit the Development of Cutaneous Squamous Cell Carcinoma by Regulating the hsa_circ_0070934/miR-136-5p/PRAF2 Axis

Xiong W, Wu L, Tang R, Zhang Q, Guo Q, Song S

Cancer Management and Research 2021, 13:4359-4371

Published Date: 1 June 2021

Review

The Functional Hallmarks of Cancer Predisposition Genes

Capellini A, Williams M, Onel K, Huang KL

Cancer Management and Research 2021, 13:4351-4357

Published Date: 1 June 2021

Magnitude and Associated Factors of Suicidal Ideation Among Cancer Patients at Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia, 2019: Cross-sectional Study

Hagezom HM, Amare T, Hibdye G, Demeke W

Cancer Management and Research 2021, 13:4341-4350

Published Date: 1 June 2021

The Incidence, Risk Factors, and Patterns of Peripherally Inserted Central Catheter-Related Venous Thrombosis in Cancer Patients Followed Up by Ultrasound

Li X, Wang G, Yan K, Yin S, Wang H, Wang Y, Bai X, Shen Y

Cancer Management and Research 2021, 13:4329-4340

Published Date: 1 June 2021

MRI Evaluation of Complete Response of Locally Advanced Rectal Cancer After Neoadjuvant Therapy: Current Status and Future Trends

Xu Q, Xu Y, Sun H, Jiang T, Xie S, Ooi BY, Ding Y

Cancer Management and Research 2021, 13:4317-4328

Published Date: 1 June 2021

CircFAT1 is Overexpressed in Colorectal Cancer and Suppresses Cancer Cell Proliferation, Invasion and Migration by Increasing the Maturation of miR-10a

Liu M

Cancer Management and Research 2021, 13:4309-4315

Published Date: 1 June 2021

Combining Lactate Dehydrogenase and Fibrinogen: Potential Factors to Predict Therapeutic Efficacy and Prognosis of Patients with Small-Cell Lung Cancer

Huang W, Liu P, Zong M, Chen QQ, Zhou H, Kong H, Xie WP

Cancer Management and Research 2021, 13:4299-4307

Published Date: 31 May 2021

Investigation of Chromosome 1 Aberrations in the Lymphocytes of Prostate Cancer and Benign Prostatic Hyperplasia Patients by Fluorescence in situ Hybridization

Miszczyk J, Przydacz M, Zembrzuski M, Chłosta PL

Cancer Management and Research 2021, 13:4291-4298

Published Date: 31 May 2021

Rare DNA Mismatch Repair-Related Protein Loss in Patients with Intrahepatic Cholangiocarcinoma and Combined Hepatocellular-Cholangiocarcinoma and Their Response to Immunotherapy

Yu J, Zhang X, Huang Q, Tan S, Xiong X, Gou H

Cancer Management and Research 2021, 13:4283-4290

Published Date: 31 May 2021

circRNA-TBC1D4, circRNA-NAALAD2 and circRNA-TGFBR3: Selected Key circRNAs in Neuroblastoma and Their Associations with Clinical Features

Lin W, Wang Z, Wang J, Yan H, Han Q, Yao W, Li K

Cancer Management and Research 2021, 13:4271-4281

Published Date: 28 May 2021

Cost-Effectiveness Analysis of Dacomitinib versus Gefitinib in the First-Line Treatment of EGFR-Positive Advanced or Metastatic Non-Small Cell Lung Cancer

Zhang L, Li N, Liu M, Zheng B, Wu Z, Cai H

Cancer Management and Research 2021, 13:4263-4270

Published Date: 28 May 2021

Recent Advances in the Potential Use of Circular RNA for the Diagnosis and Treatment of Pancreatic Cancer

Sun X, Liu D, Ge N, Guo J, Wang S, Liu X, Wang G, Sun S

Cancer Management and Research 2021, 13:4251-4262

Published Date: 28 May 2021

Original Research

Real-World, Single-Center Data for Lenalidomide Plus Rituximab in Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Transformed Follicular Lymphoma

Lee YP, Hong JY, Yoon SE, Cho J, Shim JH, Bang Y, Kim WS, Kim SJ

Cancer Management and Research 2021, 13:4241-4250

Published Date: 28 May 2021

Lenvatinib Plus Camrelizumab versus Lenvatinib Monotherapy as Post-Progression Treatment for Advanced Hepatocellular Carcinoma: A Short-Term Prognostic Study

Wei F, Huang Q, He J, Luo L, Zeng Y

Cancer Management and Research 2021, 13:4233-4240

Published Date: 27 May 2021

Review

Remodelling and Treatment of the Blood-Brain Barrier in Glioma

Wang Y, Zhang F, Xiong N, Xu H, Chai S, Wang H, Wang J, Zhao H, Jiang X, Fu P, Xiang W

Cancer Management and Research 2021, 13:4217-4232

Published Date: 27 May 2021

Distribution of Peripheral Blood Cells in Esophageal Cancer Patients During Concurrent Chemoradiotherapy Predicts Long-Term Locoregional Progression Hazard After Treatment (GASTO1072)

Xu L, Chen J, Guo H, Huang R, Guo L, Yu II Y, Zhai T, Wu F, Chen Z, Li D, Chen C

Cancer Management and Research 2021, 13:4203-4215

Published Date: 25 May 2021

A Nomogram Model Involving Preoperative Fibrinogen and Prognostic Nutritional Index Score for Predicting Postoperative Outcome in Patients with Gastric Cancer

Wang P, Wang H, Qiu G, Liu J, Fan L, Liao X, Che X

Cancer Management and Research 2021, 13:4191-4201

Published Date: 25 May 2021

USP8 is a Novel Therapeutic Target in Melanoma Through Regulating Receptor Tyrosine Kinase Levels

Duan B, Wang C, Liu Z, Yang X

Cancer Management and Research 2021, 13:4181-4189

Published Date: 24 May 2021

Fibrinogen–Albumin Ratio Index (FARI) as a Certain Prognostic Biomarker in Pretreated Patients with Immunotherapy

Guo Z, Liang J

Cancer Management and Research 2021, 13:4169-4180

Published Date: 24 May 2021

Preoperative C-Reactive Protein/Albumin Ratio is a Prognostic Indicator for Survival in Surgically Treated Gastrointestinal Stromal Tumors: A Retrospective Cohort Study

Cao X, Cui J, Li Z, Zhao G

Cancer Management and Research 2021, 13:4155-4167

Published Date: 24 May 2021

HOXA9 Expression is Associated with Advanced Tumour Stage and Prognosis in Nasopharyngeal Carcinoma

Liu T, Ji C, Sun Y, Bai W

Cancer Management and Research 2021, 13:4147-4154

Published Date: 21 May 2021

Absolute Circulating Leukemic Cells as a Risk Factor for Early Bleeding Events in Patients with Non-High-Risk Acute Promyelocytic Leukemia

Pei Y, Shi M, Song J, Niu X, Wei S, Dou L, Xiao M, Li D, Xu F, Bai Y, Sun K

Cancer Management and Research 2021, 13:4135-4146

Published Date: 21 May 2021

The Correlation Between Mutant p53 Protein Expression and Cell Atypia in Early Differentiated Gastric Adenocarcinoma

Tang M, Liu PJ, Yue B, Yang XT, Chen GY

Cancer Management and Research 2021, 13:4129-4134

Published Date: 20 May 2021

Efficacy and Safety of Anlotinib in Patients with Advanced Non-Small Cell Lung Cancer: A Real-World Study

Zhong Q, Liu Z

Cancer Management and Research 2021, 13:4115-4128

Published Date: 20 May 2021

LncRNA SNHG16 Facilitates Nasopharyngeal Carcinoma Progression by Acting as ceRNA to Sponge miR-520a-3p and Upregulate MAPK1 Expression

Wu Q, Zhao Y, Shi R, Wang T

Cancer Management and Research 2021, 13:4103-4114

Published Date: 20 May 2021

Review

Overview of Antabuse® (Disulfiram) in Radiation and Cancer Biology

Jia Y, Huang T

Cancer Management and Research 2021, 13:4095-4101

Published Date: 20 May 2021

A Community Hospital-Based Study: A Prespecified Neutrophil Count with Adjuvant mFOLFOX6 Associated with Increased Delays, Increased G-CSF Use, and Reduced Dose Intensity

Chiarotto JA, Dranitsaris G

Cancer Management and Research 2021, 13:4087-4094

Published Date: 19 May 2021

Metformin Use and the Outcome of Metastatic Renal Cell Carcinoma Treated with Sunitinib or Pazopanib

Fiala O, Ostašov P, Rozsypalová A, Hora M, Šorejs O, Šustr J, Bendová B, Trávníček I, Filipovský J, Fínek J, Büchler T

Cancer Management and Research 2021, 13:4077-4086

Published Date: 21 May 2021

Polysaccharide-Based Lotus Seedpod Surface-Like Porous Microsphere as an Efficient Drug Carrier for Cancer Treatment

Wu Y, Zhang J, Ni J, Yang Z, Chen K, Zheng L, He Z

Cancer Management and Research 2021, 13:4067-4076

Published Date: 18 May 2021

Overexpression of Tumour Necrosis Factor-α-Induced Protein 8 is Associated with Prognosis in Colon Cancer

Zhang X, Li Z, Sun Y, Liu G, Liu X, Zhou Y

Cancer Management and Research 2021, 13:4055-4065

Published Date: 18 May 2021

Baseline Serum Cholesterol Levels Predict the Response of Patients with Advanced Non-Small Cell Lung Cancer to Immune Checkpoint Inhibitor-Based Treatment

Tong III J, Mao Y, Yang Z, Xu Q, Zheng Z, Zhang H, Wang J, Zhang S, Rong W, Zheng III L

Cancer Management and Research 2021, 13:4041-4053

Published Date: 18 May 2021

Association of Venous Thromboembolism and Early Mortality in Patients with Newly Diagnosed Metastatic Non-Small Cell Lung Cancer

Su Y, Huo M, Hua L, Zhang Y, Yi J, Zhang S, Li J, Zhang Y

Cancer Management and Research 2021, 13:4031-4040

Published Date: 18 May 2021

Evaluation of the Benefits of TACE Combined with Sorafenib for Hepatocellular Carcinoma Based on Untreatable TACE (unTACEable) Progression

Zou X, Fan W, Xue M, Li J

Cancer Management and Research 2021, 13:4013-4029

Published Date: 18 May 2021

Analysis of Risk Factors for Surgical Complications of Endoscopic Thyroidectomy via Total Areola Approach

Wang Z, Yu J, Rao S, Lin Z, Pan Z, Shen X

Cancer Management and Research 2021, 13:4003-4012

Published Date: 18 May 2021

Original Research

The Value of Sonography in Distinguishing Follicular Thyroid Carcinoma from Adenoma

Li W, Song Q, Lan Y, Li J, Zhang Y, Yan L, Li Y, Zhang Y, Luo Y

Cancer Management and Research 2021, 13:3991-4002

Published Date: 17 May 2021

Original Research

Adenocarcinoma of High-Grade Patterns Associated with Distinct Outcome of First-Line Chemotherapy or EGFR-TKIs in Patients of Relapsed Lung Cancer

Yu X, Dong Z, Wang W, Mao S, Pan Y, Liu Y, Yang S, Chen B, Wang C, Li X, Zhao C, Jia K, Shao C, Wu C, Ren S, Zhou C

Cancer Management and Research 2021, 13:3981-3990

Published Date: 17 May 2021

Further Understanding of the Immune Microenvironment in Head and Neck Squamous Cell Carcinoma: Implications for Prognosis

Denaro N, Merlano MC, Lo Nigro C

Cancer Management and Research 2021, 13:3973-3980

Published Date: 17 May 2021

Original Research

Lymphadenectomy Around Inferior Mesenteric Artery in Low-Tie vs High-Tie Laparoscopic Anterior Resection: Short- and Long-Term Outcome of a Cohort of 614 Rectal Cancers

Luo Y, Yu MH, Huang YZ, Jing R, Qin J, Qin SL, Shah JN, Zhong M

Cancer Management and Research 2021, 13:3963-3971

Published Date: 14 May 2021

Original Research

Influence Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: Hashimoto’s Thyroiditis Has a Weak Effect on Central or Lateral Lymph Node Metastasis

Zhou L, Chen G, Sheng L, Liu N, Zhang B, Zeng Q, Chen B

Cancer Management and Research 2021, 13:3953-3961

Published Date: 14 May 2021

Review

Chemotherapy-Free Management of Follicular and Marginal Zone Lymphoma

Ollila TA, Olszewski AJ

Cancer Management and Research 2021, 13:3935-3952

Published Date: 14 May 2021

Application of Contrast-Enhanced Ultrasonography (CEUS) in the Assessment of Kidney Wound Recovery After Nephron-Sparing Surgery

Niu D, Li L, Du H, Shi H, Zhou J, Tai S, Xu H, Chen W, Yang C, Liang C

Cancer Management and Research 2021, 13:3925-3934

Published Date: 13 May 2021

USP5 Promotes Uterine Corpus Endometrial Carcinoma Cell Growth and Migration via mTOR/4EBP1 Activation

Li Y, Zhou J

Cancer Management and Research 2021, 13:3913-3924

Published Date: 13 May 2021

Caudate Lobe Hepatocellular Carcinoma Treated with Sequential Transarterial Chemoembolization and Iodine 125 Seeds Implantation: A Single-Center Retrospective Study

Yan L, Chen L, Qian K, Kan X, Zhang H, Liang B, Zheng C

Cancer Management and Research 2021, 13:3901-3912

Published Date: 13 May 2021

Original Research

Outcomes in Patients with pT3N0M0 Breast Cancer with and without Postmastectomy Radiotherapy

Li C, Wang J, Mo M, Yuan J, Luo J, Jin K, Wang X, Yang Y, Ma J, Mei X, Yang Z, Yu X, Chen X, Guo X

Cancer Management and Research 2021, 13:3889-3899

Published Date: 13 May 2021

Monoclonal Immunoglobulin-Associated Renal Lesions in Patients with Newly Diagnosed Multiple Myeloma: A Report from a Single Center

Lin ZS, Yu XJ, Zhang X, Wang SX, Cen XN, Zhou FD, Zhao MH

Cancer Management and Research 2021, 13:3879-3888

Published Date: 13 May 2021

Assessing Individual Risk for High-Risk Early Colorectal Neoplasm for Pre-Selection of Screening in Shanghai, China: A Population-Based Nested Case–Control Study

Shen J, Wu Y, Feng X, Liang F, Mo M, Cai B, Zhou C, Wang Z, Zhu M, Cai G, Zheng Y

Cancer Management and Research 2021, 13:3867-3878

Published Date: 12 May 2021

Aorta Calcification Increases the Risk of Anastomotic Leakage After Gastrectomy in Gastric Cancer Patients

Tao W, Cheng YX, Zou YY, Peng D, Zhang W

Cancer Management and Research 2021, 13:3857-3865

Published Date: 12 May 2021

Prediction of Risk Factors for Pathological Fracture After Bone Tumor Biopsy Using Finite Element Analysis

Iwai T, Hoshi M, Oebisu N, Orita K, Shimatani A, Takada N, Nakamura H

Cancer Management and Research 2021, 13:3849-3856

Published Date: 12 May 2021

The Clinical Significance and Biological Function of PCDH7 in Cervical Cancer

Zhang S, Fu X

Cancer Management and Research 2021, 13:3841-3847

Published Date: 12 May 2021

Circ_HIPK3 Knockdown Inhibits Cell Proliferation, Migration and Invasion of Cholangiocarcinoma Partly via Mediating the miR-148a-3p/ULK1 Pathway

You J, Wang X

Cancer Management and Research 2021, 13:3827-3839

Published Date: 11 May 2021

LNC00115 Mediates Cisplatin Resistance by Regulating the miR-7/ERK Signalling Pathway in Ovarian Cancer

Jiang X, Cheng Y, He Y, Cong S, Sun L, Wu D, Wu H, Zhang G

Cancer Management and Research 2021, 13:3817-3826

Published Date: 11 May 2021

Review

An Updated Systematic Review of Quantitative Studies Assessing Anxiety, Depression, Fear of Cancer Recurrence or Psychological Distress in Testicular Cancer Survivors

Rincones O, Smith A, Naher S, Mercieca-Bebber R, Stockler MR

Cancer Management and Research 2021, 13:3803-3816

Published Date: 11 May 2021

Depletion of Circular RNA circ_CORO1C Suppresses Gastric Cancer Development by Modulating miR-138-5p/KLF12 Axis

Fan Y, Liu M, Liu A, Cui N, Chen Z, Yang Q, Su A

Cancer Management and Research 2021, 13:3789-3801

Published Date: 11 May 2021

Circ_0001944 Contributes to Glycolysis and Tumor Growth by Upregulating NFAT5 Through Acting as a Decoy for miR-142-5p in Non-Small Cell Lung Cancer

Dou Y, Tian W, Wang H, Lv S

Cancer Management and Research 2021, 13:3775-3787

Published Date: 11 May 2021

LncRNA PCAT18 Promotes Non-Small Cell Lung Cancer Progression by Sponging miR-4319

He L, Wang J, Zhou L, Li X

Cancer Management and Research 2021, 13:3761-3774

Published Date: 10 May 2021

Free Fatty Acid is a Promising Biomarker in Triage Screening for Patients with Colorectal Cancer: A Case–Control Study

Zhu B, Zhang J, Zheng Q, Dong B, Wang M, Liu J, Cao Y

Cancer Management and Research 2021, 13:3749-3759

Published Date: 10 May 2021

Original Research

Prevalence of Medication Errors and the Associated Factors: A Prospective Observational Study Among Cancer Patients at Mbarara Regional Referral Hospital

Dorothy A, Yadesa TM, Atukunda E

Cancer Management and Research 2021, 13:3739-3748

Published Date: 10 May 2021

Knockdown of Long Non-Coding RNA HCP5 Increases Radiosensitivity Through Cellular Senescence by Regulating microRNA-128 in Gliomas

Wang C, Yu G, Xu Y, Liu C, Sun Q, Li W, Sun J, Jiang Y, Ye L

Cancer Management and Research 2021, 13:3723-3737

Published Date: 7 May 2021

Prognostic Impact of Pretreatment Elevated and Normalized Carcinoembryonic Antigen Levels After Neoadjuvant Chemoradiotherapy in Resected Locally Advanced Rectal Cancer Patients

Song J, Chen Z, Huang D, Xu B

Cancer Management and Research 2021, 13:3713-3721

Published Date: 7 May 2021

Role of Surgical Approach to Synchronous Colorectal Liver Metastases: A Retrospective Analysis

Zhai S, Sun X, Du L, Chen K, Zhang S, Shi Y, Yuan F

Cancer Management and Research 2021, 13:3699-3711

Published Date: 7 May 2021

Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro

Li CY, Chen CY, An JH, Wu JB, Shen H

Cancer Management and Research 2021, 13:3685-3697

Published Date: 7 May 2021

Serum Exosomal EphA2 is a Prognostic Biomarker in Patients with Pancreatic Cancer

Wei Q, Li Z, Feng H, Ren L

Cancer Management and Research 2021, 13:3675-3683

Published Date: 7 May 2021

The Predominant Prognostic Significance of NOTCH1 Mutation Defined by Emulsion PCR in Chronic Lymphocytic Leukemia

Skórka K, Chojnacki M, Masternak M, Karczmarczyk A, Subocz E, Wawrzyniak E, Giannopoulos K

Cancer Management and Research 2021, 13:3663-3674

Published Date: 6 May 2021

Elevated RBP-Jκ and CXCL11 Expression in Colon Cancer is Associated with an Unfavorable Clinical Outcome

Liu M, Guo H, Jiang L, Jiao M, Wang S, Tian T, Fu X, Wang W

Cancer Management and Research 2021, 13:3651-3661

Published Date: 5 May 2021

MiR-139-5p Targetedly Regulates YAF2 and Mediates the AKT/P38 MAPK Signaling Pathway to Alleviate the Metastasis of Non-Small Cell Lung Cancer Cells and Their Resistance Against Cisplatin

Yan Y, Jin X, Sun H, Pang S, Kong X, Bu J, Xu S

Cancer Management and Research 2021, 13:3639-3650

Published Date: 5 May 2021

CircRNA circ_POLA2 is Upregulated in Acute Myeloid Leukemia (AML) and Promotes Cell Proliferation by Suppressing the Production of Mature miR-34a

Li H, Bi K, Feng S, Wang Y, Zhu C

Cancer Management and Research 2021, 13:3629-3637

Published Date: 5 May 2021

Absolute Neutrophil Count in the Peripheral Blood Predicts Prognosis in Lung Cancer Patients Treated with Anlotinib

Chen R, Lu FY, Liu B, Huang J, Zhou M, Dai R, Guo Y

Cancer Management and Research 2021, 13:3619-3627

Published Date: 3 May 2021

Original Research

SDC2 and TFPI2 Methylation in Stool Samples as an Integrated Biomarker for Early Detection of Colorectal Cancer

Zhang W, Yang C, Wang S, Xiang Z, Dou R, Lin Z, Zheng J, Xiong B

Cancer Management and Research 2021, 13:3601-3617

Published Date: 30 April 2021

LINC00908 Promotes Diffuse Large B-Cell Lymphoma Development by Down-Regulating miR-671-5p

Zeng H, Wei Y, Wei X, Feng R

Cancer Management and Research 2021, 13:3589-3599

Published Date: 30 April 2021

Comprehensive Molecular Characterization of Chinese Patients with Glioma by Extensive Next-Generation Sequencing Panel Analysis

Zeng C, Wang J, Li M, Wang H, Lou F, Cao S, Lu C

Cancer Management and Research 2021, 13:3573-3588

Published Date: 29 April 2021

Study on the Appropriate Timing of Postoperative Adaptive Radiotherapy for High-Grade Glioma

Cao Y, Tang D, Xiang Y, Men L, Liu C, Zhou Q, Wu J, Huo L, Song T, Wang Y, Li Z, Wei R, Shen L, Yang Z, Hong J

Cancer Management and Research 2021, 13:3561-3572

Published Date: 28 April 2021

Efficacy and Safety of Transarterial Chemoembolization for the Treatment of Unresectable Hepatocellular Carcinoma Associated with Bile Duct Tumor Thrombus: A Real-World Retrospective Cohort Study

Feng JK, Sun JX, Liu ZH, Gu JW, Chen ZH, Liu C, Guo WX, Shi J, Cheng SQ

Cancer Management and Research 2021, 13:3551-3560

Published Date: 28 April 2021

Clinical Significance of miR-183-3p and miR-182-5p in NSCLC and Their Correlation

Zhang T, Li W, Gu M, Wang Z, Zhou S, Hao X, Li W, Xu S

Cancer Management and Research 2021, 13:3539-3550

Published Date: 28 April 2021

Assessment of Bone Health Education in US Multiple Myeloma and Solid Tumor Patients at Risk for Skeletal-Related Events

Flora DR, Carlson KB, Fuehrer DC, Cadieux B, Boike G, Schenfeld J, Lowe KA

Cancer Management and Research 2021, 13:3529-3537

Published Date: 23 April 2021

Established and Validated Novel Nomogram for Predicting Prognosis of Post-Mastectomy pN0-1 Breast Cancer without Adjuvant Radiotherapy

Qi WX, Cao L, Xu C, Zhao S, Chen J

Cancer Management and Research 2021, 13:3517-3527

Published Date: 23 April 2021

C8B in Complement and Coagulation Cascades Signaling Pathway is a predictor for Survival in HBV-Related Hepatocellular Carcinoma Patients

Zhang Y, Chen X, Cao Y, Yang Z

Cancer Management and Research 2021, 13:3503-3515

Published Date: 22 April 2021

LncRNA MAFG-AS1 Suppresses the Maturation of miR-34a to Promote Glioblastoma Cell Proliferation

Zhao H, Li J, Yan X, Bian X

Cancer Management and Research 2021, 13:3493-3501

Published Date: 22 April 2021

A Comparative Analysis of Robotic Single-Site Surgery and Laparoendoscopic Single-Site Surgery as Therapeutic Options for Stage IB1 Cervical Squamous Carcinoma

Gao J, Dang J, Chu J, Liu X, Wang J, You J, Jin Z

Cancer Management and Research 2021, 13:3485-3492

Published Date: 21 April 2021

microRNA-145-5p Inhibits Migration, Invasion, and Metastasis in Hepatocellular Carcinoma by Inhibiting ARF6

Wang S, Wang T, Gu P

Cancer Management and Research 2021, 13:3473-3484

Published Date: 21 April 2021

Effectiveness of Image-Guided Radiotherapy in Adjuvant Radiotherapy on Survival for Localized Breast Cancer: A Population-Based Analysis

Liang JA, Lee PC, Ku CP, Chen WTL, Chung CY, Kuo YC, Chou SH, Li CC, Chien CR

Cancer Management and Research 2021, 13:3465-3472

Published Date: 20 April 2021

Role of Chronic Inflammatory Ratios in Predicting Recurrence of Resected Patients with Stage I–III Mucinous Colorectal Adenocarcinoma

Liao YC, Ying HQ, Huang Y, Luo YR, Xiong CF, Nie RW, Li XJ, Cheng XX

Cancer Management and Research 2021, 13:3455-3464

Published Date: 20 April 2021

HER2 Overexpression and Mismatch Repair Deficiency are Correlated with Malignancy in Colorectal Cancer

Luo H, Cui L, Shen K, Li R, Wang Z, Xie Z

Cancer Management and Research 2021, 13:3443-3454

Published Date: 20 April 2021

RETRACTED ARTICLE: Matrine Regulates Proliferation, Apoptosis, Cell Cycle, Migration, and Invasion of Non-Small Cell Lung Cancer Cells Through the circFUT8/miR-944/YES1 Axis

Zhu H, Lu Q, Lu Q, Shen X, Yu L

Cancer Management and Research 2021, 13:3429-3442

Published Date: 19 April 2021

XPG is Modulated by miR-4715-3p and rs873601 Genotypes in Lung Cancer

Yu W, Yao J, Lyu P, Zhou J, Chen X, Liu X, Xiao S

Cancer Management and Research 2021, 13:3417-3427

Published Date: 19 April 2021

Value of Combining Clinical Factors, Conventional Ultrasound, and Contrast-Enhanced Ultrasound Features in Preoperative Prediction of Central Lymph Node Metastases of Different Sized Papillary Thyroid Carcinomas

Wang Y, Nie F, Wang G, Liu T, Dong T, Sun Y

Cancer Management and Research 2021, 13:3403-3415

Published Date: 19 April 2021

Original Research

IL-37 Was Involved in Progress of Acute Myeloid Leukemia Through Regulating IL-6 Expression

Wei X, Li Y, Zhang G, Wang N, Mi M, Xin Y, Jiang H, Sun C

Cancer Management and Research 2021, 13:3393-3402

Published Date: 19 April 2021

The Effect of the Prognostic Nutritional Index on the Toxic Side Effects of Radiochemotherapy and Prognosis After Radical Surgery for Gastric Cancer

Liu JY, Dong HM, Wang WL, Wang G, Pan H, Chen WW, Wang Q, Wang ZJ

Cancer Management and Research 2021, 13:3385-3392

Published Date: 16 April 2021

Upregulation of Family with Sequence Similarity 83 Member D Expression Enhances Cell Proliferation and Motility via Activation of Wnt/β-Catenin Signaling and Predicts Poor Prognosis in Gastric Cancer [Corrigendum]

Wang F, Zhang S, Wei Y, Chen H, Jiao Z, Li Y

Cancer Management and Research 2021, 13:3381-3383

Published Date: 16 April 2021

Original Research

Machine Learning Models to Improve the Differentiation Between Benign and Malignant Breast Lesions on Ultrasound: A Multicenter External Validation Study

Huo L, Tan Y, Wang S, Geng C, Li Y, Ma X, Wang B, He Y, Yao C, Ouyang T

Cancer Management and Research 2021, 13:3367-3379

Published Date: 16 April 2021

Microwave Ablation of Small Hepatic Metastases Using MR Guidance and Monitoring: Clinical Safety and Efficacy

Li Z, Jiao D, Wang C, Li J, Liu Z, Zhang W, Han X

Cancer Management and Research 2021, 13:3357-3366

Published Date: 16 April 2021

Factors Related to Instrumentation Failure in Titanium Mesh Reconstruction for Thoracic and Lumbar Tumors: Retrospective Analysis of 178 Patients

Bao WD, Jia Q, Wang T, Lou Y, Jiang DJ, Yang C, Yang X, Huang Q, Wei HF, Xiao JR

Cancer Management and Research 2021, 13:3345-3355

Published Date: 15 April 2021

Original Research

Solid-Pseudopapillary Neoplasm of the Pancreas: A 63-Case Analysis of Clinicopathologic and Immunohistochemical Features and Risk Factors of Malignancy

Chen H, Huang Y, Yang N, Yan W, Yang R, Zhang S, Yang P, Li N, Feng Z

Cancer Management and Research 2021, 13:3335-3343

Published Date: 15 April 2021

Original Research

Esophagogastric Cancer After Sleeve Gastrectomy: A Systematic Review of Case Reports

Chen W, Wang Y, Zhu J, Wang C, Dong Z

Cancer Management and Research 2021, 13:3327-3334

Published Date: 15 April 2021

CT-Guided 125I Brachytherapy in the Treatment of Hepatocellular Carcinoma Refractory to Conventional Transarterial Chemoembolization: A Pilot Study

Xu X, Ding Y, Pan T, Gao F, Huang X, Sun Q

Cancer Management and Research 2021, 13:3317-3326

Published Date: 15 April 2021

Prognostic Value of the TP53 Mutation Location in Metastatic Breast Cancer as Detected by Next-Generation Sequencing

Bai H, Yu J, Jia S, Liu X, Liang X, Li H

Cancer Management and Research 2021, 13:3303-3316

Published Date: 15 April 2021

Impact of Radiotherapy Pattern on the Prognosis of Stage IV Lung Adenocarcinomas Harboring EGFR Mutations

Zhang Y, Wang W, Xu X, Li Y, Zhang H, Li J, Li Z

Cancer Management and Research 2021, 13:3293-3301

Published Date: 15 April 2021

The Prognosis Value of PSPC1 Expression in Nasopharyngeal Cancer

He H, Zhang L, Lin K, Huang Z, Zhou Y, Lin S, Su Y, Pan J

Cancer Management and Research 2021, 13:3281-3291

Published Date: 14 April 2021

The Roles of Transmembrane Mucins Located on Chromosome 7q22.1 in Colorectal Cancer

Almasmoum H

Cancer Management and Research 2021, 13:3271-3280

Published Date: 14 April 2021

Clinical Significance of Preoperative Fibrinogen to Albumin Ratio in Patients with Glioblastoma: A Singe Center Experience

Li J, Zhou X, Xiang Y, Zhang S, Feng W, Yuan Y, Liu Y, Yin S

Cancer Management and Research 2021, 13:3259-3269

Published Date: 14 April 2021

Silencing of Long Non-Coding RNA HOTAIR Alleviates Epithelial–Mesenchymal Transition in Pancreatic Cancer via the Wnt/β-Catenin Signaling Pathway

Tang Y, Song G, Liu H, Yang S, Yu X, Shi L

Cancer Management and Research 2021, 13:3247-3257

Published Date: 14 April 2021

Development of a Joint Prediction Model Based on Both the Radiomics and Clinical Factors for Predicting the Tumor Response to Neoadjuvant Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer

Liu Y, Zhang FJ, Zhao XX, Yang Y, Liang CY, Feng LL, Wan XB, Ding Y, Zhang YW

Cancer Management and Research 2021, 13:3235-3246

Published Date: 13 April 2021

Original Research

Prognostic Factors for Patients with Esophageal Cancer Receiving Definitive Radiotherapy Alone: A Retrospective Analysis

Jiang N, Ge XL, Zhang ZY, Liu J, Wang PP, Sun XC, Yang M

Cancer Management and Research 2021, 13:3229-3234

Published Date: 13 April 2021

Combined Diagnostic Significance of Preoperative Serum β2-Microglobulin and Routine Blood Test in Patients with High-Grade Glioma and Solitary Brain Metastasis [Erratum]

Li L, Bu X, Wu B, Zhang S, Jin K, Xia L, Sun C

Cancer Management and Research 2021, 13:3227-3228

Published Date: 15 April 2021

Optimizing Dose-Adjusted EPOCH Chemotherapy with Long-Acting Granulocyte Colony-Stimulating Factor During the COVID-19 Epidemic

Wei C, Zhang Y, Wang W, Zhang W

Cancer Management and Research 2021, 13:3219-3225

Published Date: 13 April 2021

The Prognostic Significance of Sarcopenia and the Neutrophil-to-Lymphocyte Ratio in Elderly Patients with Esophageal Squamous Cell Carcinoma

Peng H, Tan X

Cancer Management and Research 2021, 13:3209-3218

Published Date: 13 April 2021

Clinical Characteristics and Prognosis Analysis of Infantile Hepatoblastoma—A 15-Year Retrospective Single-Center Study

Zhi T, Zhang W, Zhang Y, Hu H, Huang D

Cancer Management and Research 2021, 13:3201-3208

Published Date: 13 April 2021

Nomogram for Predicting Anastomotic Leakage after Rectal Cancer Surgery in Elderly Patients with Dysfunctional Stomata

Li C, Liang W, Chu L, Wei Y, Qin X, Yang Z, Guo W, Wang H, Wang H, Huang R

Cancer Management and Research 2021, 13:3193-3200

Published Date: 13 April 2021

Preoperative Fibrinogen–Albumin Ratio, Potential Prognostic Factors for Bladder Cancer Patients Undergoing Radical Cystectomy: A Two-Center Study

Chen J, Hao L, Zhang S, Zhang Y, Dong B, Zhang Q, Han C

Cancer Management and Research 2021, 13:3181-3192

Published Date: 12 April 2021

Long Non-Coding RNA XIST Promotes Wilms Tumor Progression Through the miR-194-5p/YAP Axis

He X, Luo X, Dong J, Deng X, Liu F, Wei G

Cancer Management and Research 2021, 13:3171-3180

Published Date: 12 April 2021

Nrf2/HO-1 Axis Regulates the Angiogenesis of Gastric Cancer via Targeting VEGF

Huang Y, Yang Y, Xu Y, Ma Q, Guo F, Zhao Y, Tao Y, Li M, Guo J

Cancer Management and Research 2021, 13:3155-3169

Published Date: 12 April 2021

Case report

Oral Tongue Cancer in a Patient with Fanconi Anemia: A Case Report and Literature Review

Deng S, Ye W, Zhang S, Zhu G, Zhang P, Song Y, Duan F, Lang J, Lu S

Cancer Management and Research 2021, 13:3145-3154

Published Date: 12 April 2021

Prognostic Significance of the L3 Skeletal Muscle Index and Advanced Lung Cancer Inflammation Index in Elderly Patients with Esophageal Cancer

Tan X, Peng H, Gu P, Chen M, Wang Y

Cancer Management and Research 2021, 13:3133-3143

Published Date: 9 April 2021

AVL9 is Upregulated in and Could Be a Predictive Biomarker for Colorectal Cancer

Li D, Zeng Y, Shen P, Lin X, Yang T, Chen B, Ma Z, Wang H

Cancer Management and Research 2021, 13:3123-3132

Published Date: 9 April 2021

Clinical Value of Detecting Tumor Endothelial Marker 8 (ANTXR1) as a Biomarker in the Diagnosis and Prognosis of Colorectal Cancer

Pietrzyk Ł, Korolczuk A, Matysek M, Arciszewski MB, Torres K

Cancer Management and Research 2021, 13:3113-3122

Published Date: 9 April 2021

The Correlation of Age with Prognosis of Atypia of Undetermined Significance and Follicular Lesion of Undetermined Significance in Thyroid Nodules

Kaliszewski K, Diakowska D, Rzeszutko M, Wojtczak B, Rudnicki J

Cancer Management and Research 2021, 13:3101-3111

Published Date: 8 April 2021

Review

Cellular Mechanism of Gene Mutations and Potential Therapeutic Targets in Ovarian Cancer

Guo T, Dong X, Xie S, Zhang L, Zeng P, Zhang L

Cancer Management and Research 2021, 13:3081-3100