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Cancer Management and Research
ISSN: 1179-1322
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Archive: Volume 10, 2018

Real-world evaluation of carboplatin plus a weekly dose of nab-paclitaxel for patients with advanced non-small-cell lung cancer with interstitial lung disease
Igawa S, Nishinarita N, Takakura A, Ozawa T, Harada S, Kusuhara S, Niwa H, Hosotani S, Sone H, Nakahara Y, Fukui T, Mitsufuji H, Yokoba M, Kubota M, Katagiri M, Sasaki J, Naoki K
Cancer Management and Research 2018, 10:7013-7019
Published Date: 14 December 2018

Prognostic value of AIB1 and EIF5A2 in intravesical recurrence after surgery for upper tract urothelial carcinoma
Huang Y, Wei J, Fang Y, Chen Z, Cen J, Feng Z, Lu J, Liang Y, Luo J, Chen W
Cancer Management and Research 2018, 10:6997-7011
Published Date: 14 December 2018

Efficacy and safety of primary surgery with postoperative radiotherapy in head and neck mucosal melanoma: a single-arm Phase II study
Yao JJ, Zhang F, Zhang GS, Deng XW, Zhang WJ, Lawrence WR, Zou L, Zhang XS, Lu LX
Cancer Management and Research 2018, 10:6985-6996
Published Date: 14 December 2018

Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival
Wang X, Chen D, Gao J, Long H, Zha H, Zhang A, Shu C, Zhou L, Yang F, Zhu B, Wu W
Cancer Management and Research 2018, 10:6971-6984
Published Date: 14 December 2018

Positive relationship between number of negative lymph nodes and duration of gallbladder cancer cause-specific survival after surgery
Lin JY, Bai DS, Zhou BH, Chen P, Qian JJ, Jin SJ, Jiang GQ
Cancer Management and Research 2018, 10:6961-6969
Published Date: 13 December 2018

Nomograms to predict overall survival and cancer-specific survival in patients with adrenocortical carcinoma
Li Y, Bian XH, Ouyang JY, Wei SY, He MZ, Luo ZL
Cancer Management and Research 2018, 10:6949-6959
Published Date: 13 December 2018

Distinct expression and prognostic value of members of the epidermal growth factor receptor family in ovarian cancer
Zhou Q, Hou CN, Yang HJ, He Z, Zuo MZ
Cancer Management and Research 2018, 10:6937-6948
Published Date: 13 December 2018

Clinical significance and effect of MTDH/AEG-1 in bladder urothelial cancer: a study based on immunohistochemistry, RNA-seq, and in vitro verification
Zhang Y, Zhang LJ, Dang YW, Li SH, Yan HB, Chen G
Cancer Management and Research 2018, 10:6921-6936
Published Date: 14 December 2018

Prognostic significance of preoperative serum CEA in primary mucinous ovarian carcinoma: a retrospective cohort study
Lin W, Cao D, Shen K
Cancer Management and Research 2018, 10:6913-6920
Published Date: 13 December 2018

MAP2K6 is associated with radiation resistance and adverse prognosis for locally advanced nasopharyngeal carcinoma patients
Li Z, Li N, Shen L
Cancer Management and Research 2018, 10:6905-6912
Published Date: 12 December 2018

Clinicopathological significance of DAPK promoter methylation in non-small-cell lung cancer: a systematic review and meta-analysis
Zhang Y, Wu J, Huang G, Xu S
Cancer Management and Research 2018, 10:6897-6904
Published Date: 12 December 2018

Key regulator of cellular metabolism, estrogen-related receptor α, a new therapeutic target in endocrine-related gynecological tumor
Liu G, Sun P, Dong B, Sehouli J
Cancer Management and Research 2018, 10:6887-6895
Published Date: 12 December 2018

An individual reference limit of the serum CEA–TPA–CA 15-3 tumor marker panel in the surveillance of asymptomatic women following surgery for primary breast cancer
Nicolini A, Carpi A, Ferrari P, Morganti R, Mazzotti V, Barak V, Duffy MJ
Cancer Management and Research 2018, 10:6879-6886
Published Date: 13 December 2018

The number of resected lymph nodes is associated with the long-term survival outcome in patients with T2 N0 non-small cell lung cancer
Wen YS, Xi KX, Xi KX, Zhang RS, Wang GM, Huang ZR, Zhang LJ
Cancer Management and Research 2018, 10:6869-6877
Published Date: 12 December 2018

HJC0152, a novel STAT3 inhibitor with promising anti-tumor effect in gastric cancer
Jiang X, Wu M, Xu Z, Wang H, Wang H, Yu X, Li Z, Teng L
Cancer Management and Research 2018, 10:6857-6867
Published Date: 12 December 2018

Nomograms for predicting survival outcomes in patients with primary tracheal tumors: a large population-based analysis
Wen J, Liu D, Xu X, Chen D, Chen Y, Sun L, Chen J, Fan M
Cancer Management and Research 2018, 10:6843-6856
Published Date: 11 December 2018

The efficacy and safety of apatinib in Ewing’s sarcoma: a retrospective analysis in one institution
Wang Y, Min L, Zhou Y, Luo Y, Duan H, Tu C
Cancer Management and Research 2018, 10:6835-6842
Published Date: 11 December 2018

The clinical promise of immunotherapy in triple-negative breast cancer
Vikas P, Borcherding N, Zhang W
Cancer Management and Research 2018, 10:6823-6833
Published Date: 10 December 2018

Prognosis of rare pathological primary urethral carcinoma
Abudurexiti M, Wang J, Shao N, Wan FN, Zhu Y, Dai B, Ye D
Cancer Management and Research 2018, 10:6815-6822
Published Date: 7 December 2018

Fertility-preserving treatment in women with early endometrial cancer: the Chinese experience
Wang Y, Yang JX
Cancer Management and Research 2018, 10:6803-6813
Published Date: 7 December 2018

The positive feedback loop between ILF3 and lncRNA ILF3-AS1 promotes melanoma proliferation, migration, and invasion
Gao G, Li W, Liu S, Han D, Yao X, Jin J, Han D, Sun W, Chen X
Cancer Management and Research 2018, 10:6791-6802
Published Date: 11 December 2018

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo
Wang J, Liang H, Sun M, Zhang L, Xu H, Liu W, Li Y, Zhou Y, Li Y, Li M
Cancer Management and Research 2018, 10:6779-6790
Published Date: 7 December 2018


Improved virtual surgical planning with 3D-multimodality image for malignant giant pelvic tumors


Fang X, Yu Z, Xiong Y, Yuan F, Liu H, Wu F, Zhang W, Luo Y, Song L, Tu C, Duan H
Cancer Management and Research 2018, 10:6769-6777
Published Date: 7 December 2018

MALAT1: a potential biomarker in cancer
Li ZX, Zhu QN, Zhang HB, Hu Y, Wang G, Zhu YS
Cancer Management and Research 2018, 10:6757-6768
Published Date: 6 December 2018

Whole-body magnetic resonance imaging for the assessment of metastatic breast cancer

Godinho MV, Lopes FP, Costa FM
Cancer Management and Research 2018, 10:6743-6756
Published Date: 6 December 2018


Hematologic toxicity is rare in relapsed patients treated with belinostat: a systematic review of belinostat toxicity and safety in peripheral T-cell lymphomas


Allen PB, Lechowicz MJ
Cancer Management and Research 2018, 10:6731-6742
Published Date: 6 December 2018

Anticancer efficiency of cycloartane triterpenoid derivatives isolated from Cimicifuga yunnanensis Hsiao on triple-negative breast cancer cells
Li X, Wang W, Fan Y, Wei Y, Yu LQ, Wei JF, Wang YF
Cancer Management and Research 2018, 10:6715-6729
Published Date: 6 December 2018

Comparison of totally laparoscopic and open approach in total gastrectomy with D2 lymphadenectomy – systematic review and meta-analysis
Małczak P, Torbicz G, Rubinkiewicz M, Gajewska N, Sajuk N, Rozmus K, Wysocki M, Major P, Budzyński A, Pędziwiatr M
Cancer Management and Research 2018, 10:6705-6714
Published Date: 6 December 2018

Comparison between NOD/SCID mice and BALB/c mice for patient-derived tumor xenografts model of non-small-cell lung cancer
Wu J, Zhang J, Jiang M, Zhang T, Wang Y, Wang Z, Miao Y, Wang Z, Li W
Cancer Management and Research 2018, 10:6695-6703
Published Date: 6 December 2018

IL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis
Browning L, Patel MR, Bring Horvath E, Tawara K, Jorcyk CL
Cancer Management and Research 2018, 10:6685-6693
Published Date: 5 December 2018

Total lymphocyte count, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio as prognostic factors in advanced non–small cell lung cancer with chemoradiotherapy
Song X, Chen D, Yuan M, Wang H, Wang Z
Cancer Management and Research 2018, 10:6677-6683
Published Date: 5 December 2018

Low STYK1 expression indicates poor prognosis in gastric cancer
Fang J, Wang H, Fang X, Li N, Hu H, Bian M, Yang P
Cancer Management and Research 2018, 10:6669-6676
Published Date: 6 December 2018

Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer
Zhu X, Chen H, Yang Y, Xu C, Zhou J, Zhou J, Chen Y
Cancer Management and Research 2018, 10:6649-6668
Published Date: 5 December 2018

Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells
Wang J, Liu C, Chang X, Qi Y, Zhu Z, Yang X
Cancer Management and Research 2018, 10:6641-6647
Published Date: 4 December 2018

Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients
Xiong G, Yao L, Hong P, Yang L, Ci W, Liu L, He Q, Gong K, Li X, Zhou L
Cancer Management and Research 2018, 10:6627-6639
Published Date: 4 December 2018

A nomogram to predict prognosis in patients undergoing sublobar resection for stage IA non-small-cell lung cancer
Yang H, Li X, Shi J, Fu H, Yang H, Liang Z, Xiong H, Wang H
Cancer Management and Research 2018, 10:6611-6626
Published Date: 4 December 2018

Long non-coding RNA 1308 promotes cell invasion by regulating the miR-124/ADAM 15 axis in non-small-cell lung cancer cells
Li H, Guo X, Li Q, Ran P, Xiang X, Yuan Y, Dong T, Zhu B, Wang L, Li F, Yang C, Mu D, Wang D, Xiao C, Zheng S
Cancer Management and Research 2018, 10:6599-6609
Published Date: 3 December 2018

Classification of positive surgical margins and tumor recurrence after nephron-sparing surgery for small renal masses
Li G, Zhu DS, Lang ZQ, Wang AX, Li YH, Zhang RY, Niu YJ
Cancer Management and Research 2018, 10:6591-6598
Published Date: 3 December 2018

The clinical significance of CCBE1 expression in human colorectal cancer
Zhao YR, Liu H, Xiao LM, Jin CG, Zhang ZP, Yang CG
Cancer Management and Research 2018, 10:6581-6590
Published Date: 30 November 2018

Human epithelial growth factor receptor 2 in human salivary carcinoma ex pleomorphic adenoma: a potential therapeutic target
Xia L, Wang Y, Hu Y, Zhang C, Gu T, Wang L, Li J, Yu W, Tian Z
Cancer Management and Research 2018, 10:6571-6579
Published Date: 30 November 2018

Impact of inflammatory markers on survival in patients with limited disease small-cell lung cancer undergoing chemoradiotherapy
Bernhardt D, Aufderstrasse S, König L, Adeberg S, Bozorgmehr F, Christopoulos P, El Shafie RA, Hörner-Rieber J, Kappes J, Thomas M, Herth F, Steins M, Debus J, Rieken S
Cancer Management and Research 2018, 10:6563-6569
Published Date: 30 November 2018

Efficacy and safety of crizotinib in patients with anaplastic lymphoma kinase-positive advanced-stage non-small-cell lung cancer
Mohieldin A, Rasmy A, Ashour M, Al-Nassar M, Ali RH, El-Enezi FG
Cancer Management and Research 2018, 10:6555-6561
Published Date: 29 November 2018

Breast cancer laterality and molecular subtype likely share a common risk factor
Cheng SA, Liang LZ, Liang QL, Huang ZY, Peng XX, Hong XC, Luo XB, Yuan GL, Zhang HJ, Jiang L
Cancer Management and Research 2018, 10:6549-6554
Published Date: 29 November 2018

miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer
Fang Y, Liang X, Xu J, Cai X
Cancer Management and Research 2018, 10:6537-6547
Published Date: 29 November 2018

Radiotherapy improves the survival of patients with extensive-disease small-cell lung cancer: a propensity score matched analysis of Surveillance, Epidemiology, and End Results database
Zhang R, Li P, Li Q, Qiao Y, Xu T, Ruan P, Song Q, Fu Z
Cancer Management and Research 2018, 10:6525-6535
Published Date: 29 November 2018

STAT1 inhibits STAT3 activation in esophageal squamous cell carcinoma
Liu Z, Zhang Y, Chen Y, Lin Y, Lin Z, Wang H
Cancer Management and Research 2018, 10:6517-6523
Published Date: 29 November 2018

Germline BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance associated with breast/ovarian cancer: a report from North India
Mehta A, Vasudevan S, Sharma SK, Kumar D, Panigrahi M, Suryavanshi M, Gupta G
Cancer Management and Research 2018, 10:6505-6516
Published Date: 30 November 2018

Identification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets
Chen Q, Zeng X, Huang D, Qiu X
Cancer Management and Research 2018, 10:6489-6504
Published Date: 28 November 2018

Managing the cancer–work interface: the effect of cancer survivorship on unemployment
Tracy JK, Falk D, Thompsom RJ, Scheindlin L, Adetunji F, Swanberg JE
Cancer Management and Research 2018, 10:6479-6487
Published Date: 28 November 2018

A radiomics-based formula for the preoperative prediction of postoperative pancreatic fistula in patients with pancreaticoduodenectomy
Zhang WY, Cai W, He B, Xiang N, Fang C, Jia F
Cancer Management and Research 2018, 10:6469-6478
Published Date: 28 November 2018

Orchestration of immune checkpoints in tumor immune contexture and their prognostic significance in esophageal squamous cell carcinoma
Zhao JJ, Zhou ZQ, Wang P, Chen CL, Liu Y, Pan QZ, Zhu Q, Tang Y, Weng DS, Xia JC
Cancer Management and Research 2018, 10:6457-6468
Published Date: 28 November 2018

Inhibiting GIT1 reduces the growth, invasion, and angiogenesis of osteosarcoma
Zhang Z, Hu P, Xiong J, Wang S
Cancer Management and Research 2018, 10:6445-6455
Published Date: 29 November 2018

NLRP6, decreased in gastric cancer, suppresses tumorigenicity of gastric cancer cells
Wang Q, Wang C, Chen J
Cancer Management and Research 2018, 10:6431-6444
Published Date: 27 November 2018

Local ablative therapy with or without chemotherapy for non-small-cell lung cancer patients with postoperative oligometastases
Shang S, Su Y, Zhu Z, Li B, Guo M, Xu Y, Sun X, Wang L, Yu J
Cancer Management and Research 2018, 10:6421-6429
Published Date: 27 November 2018

Specific clinical and immune features of CD68 in glioma via 1,024 samples
Wang L, Zhang C, Zhang Z, Han B, Shen Z, Li L, Liu S, Zhao X, Ye F, Zhang Y
Cancer Management and Research 2018, 10:6409-6419
Published Date: 27 November 2018

Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma
Ye Y, Wu Y, Wang J
Cancer Management and Research 2018, 10:6399-6407
Published Date: 27 November 2018

Clinical outcomes of stereotactic body radiotherapy for de novo pulmonary tumors in patients with completely resected early stage non-small cell lung cancer
Zhao Q, Chen G, Ye L, Zeng Z, Shi S, He J
Cancer Management and Research 2018, 10:6391-6398
Published Date: 28 November 2018

Identification of mTOR inhibitor-resistant genes in cutaneous squamous cell carcinoma
Yu SL, Lee DC, Baek, SW, Cho DY, Choi JG, Kang J
Cancer Management and Research 2018, 10:6379-6389
Published Date: 27 November 2018

Integrated mitochondrial function and cancer-related fatigue in men with prostate cancer undergoing radiation therapy
Hsiao CP, Chen MK, Daly B, Hoppel C
Cancer Management and Research 2018, 10:6367-6377
Published Date: 26 November 2018

Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer
Yazarlou F, Modarressi MH, Mowla SJ, Kholghi Oskooei V, Motevaseli E, Farhady Tooli L, Nekoohesh L, Eghbali M, Ghafouri-Fard S, Afsharpad M
Cancer Management and Research 2018, 10:6357-6365
Published Date: 26 November 2018

Uridine-cytidine kinase 2 promotes metastasis of hepatocellular carcinoma cells via the Stat3 pathway
Zhou Q, Jiang H, Zhang J, Yu W, Zhou Z, Huang P, Wang J, Xiao Z
Cancer Management and Research 2018, 10:6339-6355
Published Date: 26 November 2018

PRISMA – Practical meta-analysis of applying local triamcinolone acetonide injection for stenosis after esophageal cancer surgery
Wang W, Shen Z, Du B, Pang Y
Cancer Management and Research 2018, 10:6327-6338
Published Date: 26 November 2018

Usefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection [Corrigendum]
Guo Y, Chen F, Cui W
Cancer Management and Research 2018, 10:6325-6326
Published Date: 26 November 2018

Development of a prediction model for pancreatic cancer in patients with type 2 diabetes using logistic regression and artificial neural network models
Hsieh MH, Sun LM, Lin CL, Hsieh MJ, Hsu CY, Kao CH
Cancer Management and Research 2018, 10:6317-6324
Published Date: 26 November 2018

Let-7a inhibits osteosarcoma cell growth and lung metastasis by targeting Aurora-B
Yu JJ, Pi WS, Cao Y, Peng AF, Cao ZY, Liu JM, Huang SH, Liu ZL, Zhang W
Cancer Management and Research 2018, 10:6305-6315
Published Date: 26 November 2018

Anatomy of lymphatic drainage of the esophagus and lymph node metastasis of thoracic esophageal cancer
Wang Y, Zhu L, Xia W, Wang F
Cancer Management and Research 2018, 10:6295-6303
Published Date: 26 November 2018

Combined fibrinogen and neutrophil–lymphocyte ratio as a predictive factor in resectable colorectal adenocarcinoma
Li X, An B, Zhao Q, Qi J, Wang W, Zhang D, Li Z, Qin C
Cancer Management and Research 2018, 10:6285-6294
Published Date: 26 November 2018

Altered epidermal fatty acid-binding protein expression in hepatocellular carcinoma predicts unfavorable outcomes
Lu J, Cai S, Pan Y, Yun J
Cancer Management and Research 2018, 10:6275-6284
Published Date: 23 November 2018

The association between metabolic syndrome and bladder cancer susceptibility and prognosis: an updated comprehensive evidence synthesis of 95 observational studies involving 97,795,299 subjects
Peng XF, Meng XY, Wei C, Xing ZH, Huang JB, Fang ZF, Hu XQ, Liu QM, Zhu ZW, Zhou SH
Cancer Management and Research 2018, 10:6263-6274
Published Date: 26 November 2018

Association study of genetic variation of lncRNA MALAT1 with carcinogenesis of colorectal cancer
Zhao K, Jin S, Wei B, Cao S, Xiong Z
Cancer Management and Research 2018, 10:6257-6261
Published Date: 23 November 2018

Trends in incidence and mortality of female breast cancer during transition in Central China
Cheng Y, Yan Y, Gong J, Yang N, Nie S
Cancer Management and Research 2018, 10:6247-6255
Published Date: 23 November 2018

A comparison of neoadjuvant chemotherapy with gemcitabine versus docetaxel plus cisplatin in locoregionally advanced nasopharyngeal carcinoma: a propensity score matching analysis
Liu T, Sun Q, Chen J, Wang F, Li B, Qin W, Ye Z, Hu F
Cancer Management and Research 2018, 10:6237-6245
Published Date: 23 November 2018

Comparison of clinical features and outcomes in patients with extraskeletal vs skeletal Ewing sarcoma: an SEER database analysis of 3,178 cases
Jiang S, Wang G, Chen J, Dong Y
Cancer Management and Research 2018, 10:6227-6236
Published Date: 23 November 2018

Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28
Tian C, Ying HF, Zhuang RY, Zhang XW, Lu HM, Wang H, Wang SW, Li Q, Wang CG, Cai X
Cancer Management and Research 2018, 10:6217-6226
Published Date: 22 November 2018

Upregulation of KIF20A correlates with poor prognosis in gastric cancer
Sheng Y, Wang W, Hong B, Jiang X, Sun R, Yan Q, Zhang S, Lu M, Wang S, Zhang Z, Lin W, Li Y
Cancer Management and Research 2018, 10:6205-6216
Published Date: 23 November 2018

Glucose deprivation promotes apoptotic response to S1 by enhancing autophagy in human cervical cancer cells
Zhou L, Kong QH, Zhang YH, Yang W, Yan S, Li MH, Wang YD, Zhou YJ, Yu HM, Han LY
Cancer Management and Research 2018, 10:6195-6204
Published Date: 23 November 2018

miRNA-299-5p regulates estrogen receptor alpha and inhibits migration and invasion of papillary thyroid cancer cell
Wang Z, He L, Sun W, Qin Y, Dong W, Zhang T, Zhang P, Zhang H
Cancer Management and Research 2018, 10:6181-6193
Published Date: 22 November 2018

The clinical use of pretreatment NLR, PLR, and LMR in patients with esophageal squamous cell carcinoma: evidence from a meta-analysis
Sun Y, Zhang L
Cancer Management and Research 2018, 10:6167-6179
Published Date: 22 November 2018

ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer
Guo XB, Huang B, Pan YH, Su SG, Li Y
Cancer Management and Research 2018, 10:6157-6166
Published Date: 22 November 2018

Construction of a nomogram predicting the overall survival of patients with distantly metastatic non-small-cell lung cancer
Deng JQ, Ren ZP, Wen JX, Wang B, Hou XB, Xue ZQ, Chu XY
Cancer Management and Research 2018, 10:6143-6156
Published Date: 22 November 2018

Notch signaling promotes serrated neoplasia pathway in colorectal cancer through epigenetic modification of EPHB2 and EPHB4
Lian H, Jia X, Shi N, Xie S, Wang J, Wang W, Ma F, Liu H, Wang A, Cheng X, Liu C
Cancer Management and Research 2018, 10:6129-6141
Published Date: 22 November 2018

Liver surgery prolongs the survival of patients with gastrointestinal stromal tumor liver metastasis: a retrospective study from a single center
Xiao BY, Peng JH, Tang JH, Zhang RX, Li C, Lin JZ, Ding PR, Wan DS, Pan ZZ, Wu XJ
Cancer Management and Research 2018, 10:6121-6127
Published Date: 22 November 2018

Recurrence and prognostic model for identifying patients at risk for esophageal cancer after surgery
Chen D, Wang W, Chen Y, Hu J, Yang M, Mo J, Wen Z
Cancer Management and Research 2018, 10:6109-6120
Published Date: 21 November 2018

Integrated analysis reveals key genes with prognostic value in lung adenocarcinoma
Song YJ, Tan J, Gao XH, Wang LX
Cancer Management and Research 2018, 10:6097-6108
Published Date: 21 November 2018

Large-scale analysis reveals a novel risk score to predict overall survival in hepatocellular carcinoma
Zheng YJ, Liu YL, Zhao SF, Zheng ZT, Shen CY, An L, Yuan YL
Cancer Management and Research 2018, 10:6079-6096
Published Date: 21 November 2018

Radiotherapy as salvage treatment of salivary duct carcinoma in major salivary glands without radical operations
Di L, Qian K, Du C, Shen C, Zhai R, He X, Wang X, Xu T, Hu C, Ying H
Cancer Management and Research 2018, 10:6071-6078
Published Date: 21 November 2018

A Phase II study of S-1 plus oral leucovorin in heavily treated metastatic colorectal cancer patients
Hsu HC, Chou WC, Kuan FC, Lee KD, Rau KM, Huang JS, Yang TS
Cancer Management and Research 2018, 10:6061-6070
Published Date: 21 November 2018

HO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy
Yeh CN, Wu RC, Cheng CT, Tsai CY, Chang YR, Yeh TS, Wu TH, Lee WC, Chiang KC
Cancer Management and Research 2018, 10:6049-6059
Published Date: 21 November 2018

Prognostic significance of the 8th edition of the TNM classification for patients with extensive disease small cell lung cancer
Shirasawa M, Fukui T, Kusuhara S, Hiyoshi Y, Ishihara M, Kasajima M, Nakahara Y, Otani S, Igawa S, Yokoba M, Mitsufuji H, Kubota M, Katagiri M, Sasaki J, Naoki K
Cancer Management and Research 2018, 10:6039-6047
Published Date: 21 November 2018

Pretreatment neutrophil to lymphocyte and platelet to lymphocyte ratios as predictive factors for the survival of cervical adenocarcinoma patients
Jonska-Gmyrek J, Gmyrek L, Zolciak-Siwinska A, Kowalska M, Fuksiewicz M, Kotowicz B
Cancer Management and Research 2018, 10:6029-6038
Published Date: 22 November 2018

Comparative effectiveness of different chemotherapy regimens of advanced-stage Hodgkin lymphoma in adults: a network meta-analysis
Zhang T, Yao Y, Feng F, Zhao W, Tian J, Zhou C, Wang X, Dong S, Li J, Qi L, Sun C
Cancer Management and Research 2018, 10:6017-6028
Published Date: 22 November 2018

Prognostic impact of lactic dehydrogenase to albumin ratio in hepatocellular carcinoma patients with Child–Pugh I who underwent curative resection: a prognostic nomogram study [Erratum]
Gan W, Zhang MX, Wang JX, Fu YP, Huang JL, Yi Y, Jing CY, Fan J, Zhou J, Qiu SJ
Cancer Management and Research 2018, 10:6015-6016
Published Date: 20 November 2018

High EIF2B5 mRNA expression and its prognostic significance in liver cancer: a study based on the TCGA and GEO database
Jiao Y, Fu Z, Li Y, Meng L, Liu Y
Cancer Management and Research 2018, 10:6003-6014
Published Date: 20 November 2018

U94/rep of human herpesvirus 6 inhibits proliferation, invasion, and angiogenesis of glioma
Gu B, Li L, Li M, Wang J, Zhang G, Yao K, Wang S
Cancer Management and Research 2018, 10:5991-6001
Published Date: 20 November 2018

High mobility group box 3 as an emerging biomarker in diagnosis and prognosis of hepatocellular carcinoma
Zheng W, Yang J, Dong Z, Wang L, Fang M, Wu W, Yao D, Yao M
Cancer Management and Research 2018, 10:5979-5989
Published Date: 20 November 2018

First-line chemotherapy regimens for locally advanced and metastatic pancreatic adenocarcinoma: a Bayesian analysis
Zhang S, Xie W, Zou Y, Xie S, Zhang J, Yuan W, Ma J, Zhao J, Zheng C, Chen Y, Wang C
Cancer Management and Research 2018, 10:5965-5978
Published Date: 20 November 2018

TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival
Xiao W, Wang X, Wang T, Xing J
Cancer Management and Research 2018, 10:5951-5964
Published Date: 20 November 2018

Incidence and prognostic factors of patients with synchronous liver metastases upon initial diagnosis of breast cancer: a population-based study
Zhao H, Gong Y, Ye F, Ling H, Hu X
Cancer Management and Research 2018, 10:5937-5950
Published Date: 20 November 2018

Vaginal cuff length during radical hysterectomy is a prognostic factor for stage IB-IIA cervical cancer: a retrospective study
Zuo N, Hu H, Thapa N, Li Z, Jiang D, Meng X, Yang J, Chen X, Cai H
Cancer Management and Research 2018, 10:5927-5935
Published Date: 19 November 2018

Predictors of nodal metastasis and prognostic significance of lymph node ratio and total lymph node count in tracheobronchial adenoid cystic carcinoma
Wo Y, Li S, Wang Y, Lu T, Qin Y, Sun X, Jiao W
Cancer Management and Research 2018, 10:5919-5925
Published Date: 19 November 2018

Deletion of 3p13 is a late event linked to progression of TMPRSS2:ERG fusion prostate cancer
Kluth M, Volta H, Hussein M, Taskin B, Frogh S, Möller-Koop C, Büscheck F, Jacobsen F, Tsourlakis MC, Lübke AM, Hinsch A, Clauditz T, Graefen M, Heinzer H, Huland H, Minner S, Sauter G, Wilczak W, Schlomm T, Simon R
Cancer Management and Research 2018, 10:5909-5917
Published Date: 19 November 2018

Molecular characterization and biomarker identification in colorectal cancer: Toward realization of the precision medicine dream
Goel G
Cancer Management and Research 2018, 10:5895-5908
Published Date: 19 November 2018

Development and validation of nomograms for predicting overall and breast cancer-specific survival among patients with triple-negative breast cancer
Guo LW, Jiang LM, Gong Y, Zhang HH, Li XG, He M, Sun WL, Ling H, Hu X
Cancer Management and Research 2018, 10:5881-5894
Published Date: 19 November 2018

Comparative efficacy of different targeted therapies plus fulvestrant for advanced breast cancer following progression on prior endocrine therapy: a network meta-analysis
Zhang T, Feng F, Zhao W, Yao Y, Tian J, Zhou C, Zang C, Liu C, Wang X, Sun C
Cancer Management and Research 2018, 10:5869-5880
Published Date: 16 November 2018

CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value [Corrigendum]
Xu B, Yang T, Wang Z, Zhang Y, Liu S, Shen M
Cancer Management and Research 2018, 10:5867-5868
Published Date: 16 November 2018

FPR1 mediates the tumorigenicity of human cervical cancer cells
Cao G, Zhang Z
Cancer Management and Research 2018, 10:5855-5865
Published Date: 16 November 2018

miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA
Yang X, Qiu J, Kang H, Wang Y, Qian J
Cancer Management and Research 2018, 10:5839-5853
Published Date: 16 November 2018

12-HETE facilitates cell survival by activating the integrin-linked kinase/NF-κB pathway in ovarian cancer
Liu Q, Tan W, Che J, Yuan D, Zhang L, Sun Y, Yue X, Xiao L, Jin Y
Cancer Management and Research 2018, 10:5825-5838
Published Date: 16 November 2018

Distinct prognostic value of dynactin subunit 4 (DCTN4) and diagnostic value of DCTN1, DCTN2, and DCTN4 in colon adenocarcinoma
Wang SJ, Wang Q, Zhang X, Liao X, Wang G, Yu L, Zhang W, Zhou Q, Hu S, Yuan W
Cancer Management and Research 2018, 10:5807-5824
Published Date: 16 November 2018

A 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer
Wang X, Zhou J, Xu M, Yan Y, Huang L, Kuang Y, Liu Y, Li P, Zheng W, Liu H, Jia B
Cancer Management and Research 2018, 10:5799-5806
Published Date: 16 November 2018

Metformin sensitizes hypoxia-induced gefitinib treatment resistance of HNSCC via cell cycle regulation and EMT reversal
Yin XT, Wei Z, Song CH, Tang CC, Xu WG, Wang YF, Xie JQ, Lin ZT, Han W
Cancer Management and Research 2018, 10:5785-5798
Published Date: 19 November 2018

CD24 expression and stem-associated features define tumor cell heterogeneity and tumorigenic capacities in a model of carcinogenesis
Ortiz-Montero P, Liu-Bordes WY, Londoño-Vallejo A, Vernot JP
Cancer Management and Research 2018, 10:5767-5784
Published Date: 16 November 2018

Identification and validation of a four-miRNA(miRNA-21-5p, miRNA-9-5p, miR-149-5p, and miRNA-30b-5p) prognosis signature in clear cell renal cell carcinoma
Xie MZ, Lv YF, Liu ZH, Zhang JY, Liang CY, Liao XL, Liang R, Lin Y, Li YQ
Cancer Management and Research 2018, 10:5759-5766
Published Date: 15 November 2018

CDK7 inhibition is a novel therapeutic strategy against GBM both in vitro and in vivo
Meng W, Wang J, Wang B, Liu F, Li M, Zhao Y, Zhang C, Li Q, Chen J, Zhang L, Tang Y, Ma J
Cancer Management and Research 2018, 10:5747-5758
Published Date: 15 November 2018

Enolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patients
Zhu W, Li H, Yu Y, Chen J, Chen X, Ren F, Ren Z, Cui G
Cancer Management and Research 2018, 10:5735-5745
Published Date: 15 November 2018

Circ-SFMBT2 promotes the proliferation of gastric cancer cells through sponging miR-182-5p to enhance CREB1 expression
Sun H, Xi P, Sun Z, Wang Q, Zhu B, Zhou J, Jin H, Zheng W, Tang W, Cao H, Cao X
Cancer Management and Research 2018, 10:5725-5734
Published Date: 16 November 2018

Securidaca–saponins are natural inhibitors of AKT, MCL-1, and BCL2L1 in cervical cancer cells
Obasi TC, Braicu C, Iacob BC, Bodoki E, Jurj A, Raduly L, Oniga I, Berindan-Neagoe I, Oprean R
Cancer Management and Research 2018, 10:5709-5724
Published Date: 15 November 2018

Comparison of gene expression in liver regeneration and hepatocellular carcinoma formation
Yin L, Wang Y, Guo X, Xu C, Yu G
Cancer Management and Research 2018, 10:5691-5708
Published Date: 15 November 2018

Safety and efficacy of microwave ablation for breast cancer thoracic metastases

Liu B, Wu ZJ, Mo H, He JL, Lin X, Guan J, Wei CY, Yuan ZC
Cancer Management and Research 2018, 10:5685-5689
Published Date: 14 November 2018

The contribution of XRCC3 genotypes to childhood acute lymphoblastic leukemia
Pei JS, Chang WS, Hsu PC, Chen CC, Cheng SP, Wang YC, Tsai CW, Shen TC, Bau DT
Cancer Management and Research 2018, 10:5677-5684
Published Date: 15 November 2018

Influence of marital status on small intestinal adenocarcinoma survival: an analysis of the Surveillance, Epidemiology, and End Results (SEER) database
Chen Z, Cui J, Dai W, Yang H, He Y, Song X
Cancer Management and Research 2018, 10:5667-5676
Published Date: 14 November 2018

IL-8 and thrombospondin-1 as prognostic markers in patients with metastatic colorectal cancer receiving bevacizumab
Marisi G, Scarpi E, Passardi A, Nanni O, Pagan F, Valgiusti M, Casadei Gardini A, Neri LM, Frassineti GL, Amadori D, Ulivi P
Cancer Management and Research 2018, 10:5659-5666
Published Date: 14 November 2018

Brain metastases in newly diagnosed colorectal cancer: a population-based study
Yang L, He W, Xie Q, Liu S, Kong P, Jiang C, Zhang B, Xia L
Cancer Management and Research 2018, 10:5649-5658
Published Date: 15 November 2018

Circulating tumor cells as a potential biomarker for postoperative clinical outcome in HBV-related hepatocellular carcinoma
Ye X, Li G, Han C, Han Q, Shang L, Su H, Han B, Gong Y, Lu GD, Peng T
Cancer Management and Research 2018, 10:5639-5647
Published Date: 15 November 2018

Prognosis of patients with neuroendocrine tumor: a SEER database analysis
Man D, Wu J, Shen Z, Zhu X
Cancer Management and Research 2018, 10:5629-5638
Published Date: 13 November 2018

Carotid blowout syndrome: modern trends in management
Suárez C, Fernández-Alvarez V, Hamoir M, Mendenhall WM, Strojan P, Quer M, Silver CE, Rodrigo JP, Rinaldo A, Ferlito A
Cancer Management and Research 2018, 10:5617-5628
Published Date: 13 November 2018

Prognostic value of TIGAR and LC3B protein expression in nasopharyngeal carcinoma
Wei M, Peng J, Wu P, Chen P, Yang H, Cui Y, Yang L
Cancer Management and Research 2018, 10:5605-5616
Published Date: 12 November 2018

Tumor-suppressive function of SIRT4 in neuroblastoma through mitochondrial damage
Wang Y, Guo Y, Gao J, Yuan X
Cancer Management and Research 2018, 10:5591-5603
Published Date: 9 November 2018

Gene expression of hENT1, dCK, CDA, dCMPD and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin
Kulsoom B, Shamsi TS, Afsar NA
Cancer Management and Research 2018, 10:5573-5589
Published Date: 9 November 2018

Overexpression of RALY promotes migration and predicts poor prognosis in hepatocellular carcinoma
Zhu Z, Zhang Y, Huang CS, Tang Y, Sun C, Ju W, He X
Cancer Management and Research 2018, 10:5559-5572
Published Date: 9 November 2018

Impact of the anterior commissure involvement on the survival of early glottic cancer treated with cricohyoidoepiglottopexy: a retrospective study
Allegra E, Saita V, Azzolina A, De Natale M, Bianco MR, Modica DM, Garozzo A
Cancer Management and Research 2018, 10:5553-5558
Published Date: 8 November 2018

Transarterial chemoembolization with radiofrequency ablation versus hepatectomy in hepatocellular carcinoma beyond the Milan criteria: a retrospective study
Yuan H, Cao P, Li HL, Hu HT, Guo CY, Zhao Y, Yao QJ, Geng X
Cancer Management and Research 2018, 10:5545-5552
Published Date: 8 November 2018

Risk score for non-small cell lung cancer patients starting checkpoint inhibitor treatment
Diem S, Fässler M, Hasan Ali O, Siano M, Niederer R, Berner F, Roux GA, Ackermann CJ, Schmid S, Güsewell S, Früh M, Flatz L
Cancer Management and Research 2018, 10:5537-5544
Published Date: 8 November 2018

Impact of physical activity and sleep quality on quality of life of rural residents with and without a history of cancer: findings of the Day and Night Study
Rafie C, Ning Y, Wang A, Gao X, Houlihan R
Cancer Management and Research 2018, 10:5525-5535
Published Date: 9 November 2018

The role of postoperative radiotherapy in pediatric patients with grade II intracranial ependymomas: a population-based, propensity score-matched study
Deng X, Lin D, Yu L, Xu X, Zhang N, Zhou H, Sheng H, Yin B, Lin F, Xu S, Li DD, Fang J, Lu X, Lin J
Cancer Management and Research 2018, 10:5515-5524
Published Date: 8 November 2018

Does the use of targeted agents in advanced gastroesophageal cancer increase complete response? A meta-analysis of 18 randomized controlled trials
Pang Y, Shen Z, Sun J, Wang W
Cancer Management and Research 2018, 10:5505-5514
Published Date: 12 November 2018

Upregulation of centromere protein F is linked to aggressive prostate cancers
Göbel C, Özden C, Schroeder C, Hube-Magg C, Kluth M, Möller-Koop C, Neubauer E, Hinsch A, Jacobsen F, Simon R, Sauter G, Michl U, Pehrke D, Huland H, Graefen M, Schlomm T, Luebke AM
Cancer Management and Research 2018, 10:5491-5504
Published Date: 9 November 2018

miRNA expression profiles in Smad4-positive and Smad4-negative SW620 human colon cancer cells detected by next-generation small RNA sequencing
Yan W, Liu Z, Yang W, Wu G
Cancer Management and Research 2018, 10:5479-5490
Published Date: 8 November 2018

RETRACTED ARTICLE: Osthole sensitizes with radiotherapy to suppress tumorigenesis of human nasopharyngeal carcinoma in vitro and in vivo
Peng L, Huang YT, Chen J, Zhuang YX, Zhang F, Chen JY, Zhou L, Zhang DH
Cancer Management and Research 2018, 10:5471-5477
Published Date: 8 November 2018

Identification of potential key genes associated with ovarian clear cell carcinoma
Xu Y, Shen K
Cancer Management and Research 2018, 10:5461-5470
Published Date: 8 November 2018

Histone deacetylase 6 expression in metastatic lymph nodes is a valuable prognostic marker for resected node-positive esophageal squamous cell cancer
Xie X, Luo KJ, Li Y, Ling YH, Zhang SS, Xie XY, Wen J
Cancer Management and Research 2018, 10:5451-5460
Published Date: 8 November 2018

Nomogram application to predict overall and cancer-specific survival in osteosarcoma
Zheng W, Huang Y, Chen H, Wang N, Xiao W, Liang Y, Jiang X, Su W, Wen S
Cancer Management and Research 2018, 10:5439-5450
Published Date: 8 November 2018

Feasibility single-arm study of a medical device containing Desmodium adscendens and Lithothamnium calcareum combined with chemotherapy in head and neck cancer patients
Imperatori L, Giardini D, Latini G, Migliori G, Blasi C, Bunkheila F, Breschi C, Mattioli R, Pelliccioni S, Laurino C, Vadala M, Palmieri B, Iannitti T
Cancer Management and Research 2018, 10:5433-5438
Published Date: 8 November 2018

Can contemporary trials of chemotherapy for HER2-negative metastatic breast cancer detect overall survival benefit?
Kümmel S, Jackisch C, Müller V, Schneeweiss A, Klawitter S, Lux MP
Cancer Management and Research 2018, 10:5423-5431
Published Date: 8 November 2018

Prognostic significance of combined preoperative platelet-to-lymphocyte ratio and lymphocyte-to-monocyte ratio in patients undergoing surgery with stage IB non-small-cell lung cancer
Chen Y, Wang W, Zhang X, Yu X, Xi K, Wen Y, Wang G, Feng X, Zhang L
Cancer Management and Research 2018, 10:5411-5422
Published Date: 8 November 2018

Dietary vitamin B intake and the risk of esophageal cancer: a meta-analysis
Ma JL, Zhao Y, Guo CY, Hu HT, Zheng L, Zhao EJ, Li HL
Cancer Management and Research 2018, 10:5395-5410
Published Date: 5 November 2018

Prognostic impact of lactic dehydrogenase to albumin ratio in hepatocellular carcinoma patients with Child–Pugh I who underwent curative resection: a prognostic nomogram study
Gan W, Zhang MX, Wang JX, Fu YP, Huang JL, Yi Y, Jing CY, Fan J, Zhou J, Qiu SJ
Cancer Management and Research 2018, 10:5383-5394
Published Date: 5 November 2018

Urine exosome gene expression of cancer-testis antigens for prediction of bladder carcinoma
Yazarlou F, Mowla SJ, Kholghi Oskooei V, Motevaseli E, Farhady Tooli L, Afsharpad M, Nekoohesh L, Sanikhani NS, Ghafouri-Fard S, Modarressi MH
Cancer Management and Research 2018, 10:5373-5381
Published Date: 5 November 2018

Chemotherapy combined with dendritic cell vaccine and cytokine-induced killer cells in the treatment of colorectal carcinoma: a meta-analysis
Zhou X, Mo X, Qiu J, Zhao J, Wang S, Zhou C, Su Y, Lin Z, Ma H
Cancer Management and Research 2018, 10:5363-5372
Published Date: 5 November 2018

Epigenetic regulation of HOTAIR in advanced chronic myeloid leukemia
Li Z, Luo J
Cancer Management and Research 2018, 10:5349-5362
Published Date: 5 November 2018

Ki-67 index and percentage of sarcomatoid differentiation were two independent prognostic predictors in sarcomatoid renal cell carcinoma
Wang Z, Zeng X, Chen R, Chen Z
Cancer Management and Research 2018, 10:5339-5347
Published Date: 5 November 2018

Breast cancer subtypes and the risk of distant metastasis at initial diagnosis: a population-based study
Xiao W, Zheng S, Yang A, Zhang X, Zou Y, Tang H, Xie X
Cancer Management and Research 2018, 10:5329-5338
Published Date: 5 November 2018

Diagnostic and prognostic values of the mRNA expression of excision repair cross-complementation enzymes in hepatitis B virus-related hepatocellular carcinoma
Yang L, Xu M, Cui CB, Wei PH, Wu SZ, Cen ZJ, Meng XX, Huang QG, Xie ZC
Cancer Management and Research 2018, 10:5313-5328
Published Date: 5 November 2018

A novel 12-marker panel of cancer-associated fibroblasts involved in progression of hepatocellular carcinoma
Zou B, Liu X, Gong Y, Cai C, Li P, Xing S, Pokhrel B, Zhang B, Li J
Cancer Management and Research 2018, 10:5303-5311
Published Date: 5 November 2018

Evaluation and prediction of hepatocellular carcinoma prognosis based on molecular classification
Ke K, Chen G, Cai Z, Huang Y, Zhao B, Wang Y, Liao N, Liu X, Li Z, Liu J
Cancer Management and Research 2018, 10:5291-5302
Published Date: 5 November 2018

Treatment features of systemic chemotherapy in young adults with unresectable advanced or recurrent gastric cancer
Nakayama I, Chin K, Takahari D, Ogura M, Ichimura T, Wakatsuki T, Osumi H, Ota Y, Suzuki T, Suenaga M, Shinozaki E, Yamaguchi K
Cancer Management and Research 2018, 10:5283-5290
Published Date: 1 November 2018


Transcatheter arterial chemoembolization monotherapy vs combined transcatheter arterial chemoembolization–percutaneous microwave coagulation therapy for massive hepatocellular carcinoma (≥10 cm)


Wei Y, Dai F, Zhao T, Tao C, Wang L, Ye W, Zhao W
Cancer Management and Research 2018, 10:5273-5282
Published Date: 1 November 2018

Inhibition of long non-coding RNA HOTAIR enhances radiosensitivity via regulating autophagy in pancreatic cancer
Wu CL, Yang L, Qi X, Wang TF, Li M, Xu K
Cancer Management and Research 2018, 10:5261-5271
Published Date: 2 November 2018

Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review
Zhou H, Zhu X
Cancer Management and Research 2018, 10:5247-5259
Published Date: 2 November 2018

Transanal total mesorectal excision for low rectal cancer: a case-matched study comparing TaTME versus standard laparoscopic TME
Rubinkiewicz M, Nowakowski M, Wierdak M, Mizera M, Dembiński M, Pisarska M, Major P, Małczak P, Budzyński A, Pędziwiatr M
Cancer Management and Research 2018, 10:5239-5245
Published Date: 1 November 2018

Radiofrequency ablation with systemic chemotherapy in the treatment of colorectal cancer liver metastasis: a 10-year single-center study
Ou S, Xu R, Li K, Chen Y, Kong Y, Liu H, Li J, Ouyang Y, Yu X
Cancer Management and Research 2018, 10:5227-5237
Published Date: 31 October 2018

ypTNM category combined with AJCC tumor regression grade for screening patients with the worst prognosis after neoadjuvant chemoradiation therapy for locally advanced rectal cancer
Wei JW, Huang R, Guo SP, Zhang XH, Xi SY, Wang QX, Chang H, Wang XH, Xiao WW, Zeng ZF, Gao YH
Cancer Management and Research 2018, 10:5219-5225
Published Date: 31 October 2018

Genetic variants in lncRNA HOTAIR are associated with lung cancer susceptibility in a Chinese Han population in China: a case–control study
Li H, Yang Z, Li J, Lv X, Gao M, Bi Y, Zhang Z, Wang S, Li S, Li N, Cui Z, Zhou B, Yin Z
Cancer Management and Research 2018, 10:5209-5218
Published Date: 31 October 2018

Interleukin-18 promoter genotype is associated with the risk of nasopharyngeal carcinoma in Taiwan
Huang CY, Chang WS, Tsai CW, Hsia TC, Shen TC, Bau DT, Shui HA
Cancer Management and Research 2018, 10:5199-5207
Published Date: 31 October 2018

MicroRNA-588 regulates invasion, migration and epithelial–mesenchymal transition via targeting EIF5A2 pathway in gastric cancer
Zhou X, Xu M, Guo Y, Ye L, Long L, Wang H, Tan P, Xu M
Cancer Management and Research 2018, 10:5187-5197
Published Date: 30 October 2018

MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells
Wang C, Su K, Zhang Y, Zhang W, Chu D, Zhao Q, Guo R
Cancer Management and Research 2018, 10:5171-5185
Published Date: 30 October 2018

Laparoscopic right hemicolectomy oriented by superior mesenteric artery for right colon cancer: efficacy evaluation with a match-controlled analysis

Dai W, Zhang J, Xiong W, Xu J, Cai S, Tan M, He Y, Song W, Yuan Y
Cancer Management and Research 2018, 10:5157-5170
Published Date: 30 October 2018

Downregulation of FOXO6 in breast cancer promotes epithelial–mesenchymal transition and facilitates migration and proliferation of cancer cells
Ye H, Duan M
Cancer Management and Research 2018, 10:5145-5156
Published Date: 30 October 2018

Behavior change techniques for increasing physical activity in cancer survivors: a systematic review and meta-analysis of randomized controlled trials
Finne E, Glausch M, Exner AK, Sauzet O, Stölzel F, Seidel N
Cancer Management and Research 2018, 10:5125-5143
Published Date: 30 October 2018

CCNA2 acts as a novel biomarker in regulating the growth and apoptosis of colorectal cancer
Gan Y, Li Y, Li T, Shu G, Yin G
Cancer Management and Research 2018, 10:5113-5124
Published Date: 31 October 2018

RETRACTED ARTICLE: Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer
Xue C, He Y, Hu Q, Yu Y, Chen X, Chen J, Ren F, Li J, Ren Z, Cui G, Sun R
Cancer Management and Research 2018, 10:5101-5112
Published Date: 30 October 2018

NKAP functions as an oncogene and its expression is induced by CoCl2 treatment in breast cancer via AKT/mTOR signaling pathway
Liu J, Wang H, Yin Y, Li Q, Zhang M
Cancer Management and Research 2018, 10:5091-5100
Published Date: 29 October 2018

Elevated DKK1 expression is an independent unfavorable prognostic indicator of survival in head and neck squamous cell carcinoma
Gao H, Li L, Xiao M, Guo Y, Shen Y, Cheng L, Tang M
Cancer Management and Research 2018, 10:5083-5089
Published Date: 30 October 2018

Knockdown of PRL-3 increases mitochondrial superoxide anion production through transcriptional regulation of RAP1
Yang Y, Lian S, Meng L, Tian Z, Feng Q, Wang Y, Wang P, Qu L, Shou C
Cancer Management and Research 2018, 10:5071-5081
Published Date: 30 October 2018

Pegaspargase, gemcitabine, dexamethasone, and cisplatin (P-GDP) combined chemotherapy is effective for newly diagnosed extranodal NK/T-cell lymphoma: a retrospective study
Liu T, Zhu F, Xiao Y, Li Q, Liu X, Yang K, Wu G, Zhang L
Cancer Management and Research 2018, 10:5061-5069
Published Date: 29 October 2018

Hypofractionated postoperative helical tomotherapy in prostate cancer: a mono-institutional report of toxicity and clinical outcomes
Cuccia F, Mortellaro G, Serretta V, Valenti V, Tripoli A, Gueci M, Luca N, Lo Casto A, Ferrera G
Cancer Management and Research 2018, 10:5053-5060
Published Date: 29 October 2018

NSAID consumption and risk of acute myeloid leukemia: a national population-based case-control study
Østgård LSG, Nørgaard M, Pedersen L, Østgård R, Friis LS, Schöllkopf C, Severinsen MT, Marcher CW, Medeiros BC, Jensen MK
Cancer Management and Research 2018, 10:5043-5051
Published Date: 29 October 2018

Prognostic value of plasma fibrinogen in hepatocellular carcinoma: a meta-analysis
Huang G, Jiang H, Lin Y, Wu Y, Cai W, Shi B, Luo Y, Jian Z, Zhou X
Cancer Management and Research 2018, 10:5027-5041
Published Date: 29 October 2018

Peroxiredoxin 1 silencing inhibited the growth and promoted apoptosis of pancreatic cancer cells via targeting FOXO3 gene
Sun X, Kong L, Li B, Zhang Y, Yang H
Cancer Management and Research 2018, 10:5019-5026
Published Date: 26 October 2018

Calcium channel α2δ1 subunit (CACNA2D1) enhances radioresistance in cancer stem-like cells in non-small cell lung cancer cell lines
Sui X, Geng JH, Li YH, Zhu GY, Wang WH
Cancer Management and Research 2018, 10:5009-5018
Published Date: 26 October 2018

Overexpression of lncRNA PANDAR predicts adverse prognosis in acute myeloid leukemia
Yang L, Zhou JD, Zhang TJ, Ma JC, Xiao GF, Chen Q, Deng ZQ, Lin J, Qian J, Yao DM
Cancer Management and Research 2018, 10:4999-5007
Published Date: 29 October 2018

Contrast-enhanced ultrasound for the differential diagnosis between benign and metastatic superficial lymph nodes: a meta-analysis
Mei M, Ye LG, Quan J, Huang PT
Cancer Management and Research 2018, 10:4987-4997
Published Date: 26 October 2018

Improving risk prediction for pancreatic cancer in symptomatic patients: a Saudi Arabian study
Ahmed AE, Alzahrani FS, Gharawi AM, Alammary SA, Almijmaj FH, Alhusayni FM, McClish DK, Al-Jahdali H, Al Olayan AA, Jazieh AR
Cancer Management and Research 2018, 10:4981-4986
Published Date: 25 October 2018

Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer
Ma YT, Xing XF, Dong B, Cheng XJ, Guo T, Du H, Wen XZ, Ji JF
Cancer Management and Research 2018, 10:4969-4980
Published Date: 25 October 2018

The association of XRCC1 polymorphism with osteosarcoma risk, clinicopathologic features, and prognosis in a Chinese Han population
Wu YG, Li HF, Ren YJ, Zou DB, Zhang KN, Xiao X
Cancer Management and Research 2018, 10:4959-4967
Published Date: 25 October 2018

Exosomes derived from rAAV/AFP-transfected dendritic cells elicit specific T cell-mediated immune responses against hepatocellular carcinoma
Li J, Huang SL, Zhou Z, Lin W, Chen S, Chen M, Ye Y
Cancer Management and Research 2018, 10:4945-4957
Published Date: 29 October 2018

Sarcopenia is associated with the neutrophil/lymphocyte and platelet/lymphocyte ratios in operable gastric cancer patients: a prospective study
Lin J, Zhang W, Huang Y, Chen W, Wu R, Chen X, Lou N, Wang P
Cancer Management and Research 2018, 10:4935-4944
Published Date: 25 October 2018

Microscopic hematuria predicts lower stage in patients with upper tract urothelial carcinoma
Qi N, Zhang J, Chen Y, Wen R, Li H
Cancer Management and Research 2018, 10:4929-4933
Published Date: 24 October 2018

Clinicopathological and survival analysis of uterine papillary serous carcinoma: a single institutional review of 106 cases
Wang Y, Yu M, Yang JX, Cao DY, Shen K, Lang JH
Cancer Management and Research 2018, 10:4915-4928
Published Date: 25 October 2018

The fluctuating incidence, improved survival of patients with breast cancer, and disparities by age, race, and socioeconomic status by decade, 1981–2010
Lu G, Li J, Wang S, Pu J, Sun H, Wei Z, Ma Y, Wang J, Ma H
Cancer Management and Research 2018, 10:4899-4914
Published Date: 30 October 2018

Prognostic role of derived neutrophil-to-lymphocyte ratio in surgical triple-negative breast cancer
Ren K, Yin Y, He F, Shao Y, Wang S
Cancer Management and Research 2018, 10:4891-4898
Published Date: 24 October 2018

Effects of metformin treatment on radiotherapy efficacy in patients with cancer and diabetes: a systematic review and meta-analysis
Rao M, Gao C, Guo M, Law BYK, Xu Y
Cancer Management and Research 2018, 10:4881-4890
Published Date: 24 October 2018

CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value
Xu B, Yang T, Wang Z, Zhang Y, Liu S, Shen M
Cancer Management and Research 2018, 10:4871-4880
Published Date: 23 October 2018

Dosimetric evaluation and systematic review of radiation therapy techniques for early stage node-negative breast cancer treatment
Chan TY, Tang JI, Tan PW, Roberts N
Cancer Management and Research 2018, 10:4853-4870
Published Date: 23 October 2018

Type-specific high-risk human papillomavirus viral load as a viable triage indicator for high-grade squamous intraepithelial lesion: a nested case–control study
Dong B, Sun P, Ruan G, Huang W, Mao X, Kang Y, Pan D, Lin F
Cancer Management and Research 2018, 10:4839-4851
Published Date: 23 October 2018

Comparison of the effects of stellate ganglion block and paroxetine on hot flashes and sleep disturbance in breast cancer survivors
Rahimzadeh P, Imani F, Nafissi N, Ebrahimi B, Faiz SHR
Cancer Management and Research 2018, 10:4831-4837
Published Date: 26 October 2018

Clofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways
Fan L, He Z, Head SA, Zhou Y, Lu T, Feng X, Zhang X, Zhang M, Dang Y, Jiang X, Wang M
Cancer Management and Research 2018, 10:4817-4829
Published Date: 23 October 2018

Health-related quality of life for gemcitabine and nab-paclitaxel plus radiotherapy versus gemcitabine and S-1 plus radiotherapy in patients with metastatic pancreatic cancer
Zhu X, Li F, Shi D, Ju X, Cao Y, Shen Y, Cao F, Qing S, Fang F, Jia Z, Zhang H
Cancer Management and Research 2018, 10:4805-4815
Published Date: 23 October 2018

Preoperative C-reactive protein/albumin ratio is a significant predictor of survival in bladder cancer patients after radical cystectomy: a retrospective study
Guo Y, Cai K, Mao S, Zhang J, Wang L, Zhang Z, Liu M, Zhang W, Wu Y, Yan Y, Yao X
Cancer Management and Research 2018, 10:4789-4804
Published Date: 23 October 2018

The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin
Wang X, Tian J, Jiao X, Geng J, Wang R, Liu N, Gao X, Griffin N, Gao Y, Shan F
Cancer Management and Research 2018, 10:4773-4787
Published Date: 18 October 2018

Palliative gastrectomy plus chemotherapy versus chemotherapy alone for incurable advanced gastric cancer: a meta-analysis
Wu P, Wang PL, Ma B, Yin SC, Tan YE, Hou WB, Wang ZN, Xu HM, Zhu Z
Cancer Management and Research 2018, 10:4759-4771
Published Date: 26 October 2018

Identification of chemoresistance-associated miRNAs in breast cancer
Lou W, Liu J, Ding B, Xu L, Fan W
Cancer Management and Research 2018, 10:4747-4757
Published Date: 23 October 2018

miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins
Sun Y, Hu B, Wang Y, Li Z, Wu J, Yang Y, Wei Y, Peng X, Chen H, Chen RQ, Jiang P, Fang S, Yu Z, Guo L
Cancer Management and Research 2018, 10:4735-4745
Published Date: 18 October 2018

Prognostic significance of pretreatment lymphocyte/monocyte ratio in retroperitoneal liposarcoma patients after radical resection
Luo P, Cai W, Yang L, Chen S, Wu Z, Chen Y, Zhang R, Shi Y, Yan W, Wang C
Cancer Management and Research 2018, 10:4727-4734
Published Date: 18 October 2018

Transarterial chemoembolization for hepatocellular carcinoma combined with portal vein tumor thrombosis
Lv WF, Liu KC, Lu D, Zhou CZ, Cheng DL, Xiao JK, Zhang XM, Zhang ZF
Cancer Management and Research 2018, 10:4719-4726
Published Date: 17 October 2018

Impact of the new FIGO 2013 classification on prognosis of stage I epithelial ovarian cancers
Montavon Sartorius C, Mirza U, Schötzau A, Mackay G, Fink D, Hacker NF, Heinzelmann-Schwarz V
Cancer Management and Research 2018, 10:4709-4718
Published Date: 17 October 2018

Preoperative albumin-to-globulin ratio as a significant prognostic indicator in urologic cancers: a meta-analysis
Zhang Y, Wang L, Lin S, Wang R
Cancer Management and Research 2018, 10:4695-4708
Published Date: 17 October 2018


An ioMRI-assisted case of cervical intramedullary diffuse glioma resection


Toktas ZO, Yilmaz B, Ekşi MŞ, Wang L, Akakin A, Yener Y, Konakcı M, Ayan E, Kılıc T, Konya D, Teng YD
Cancer Management and Research 2018, 10:4689-4694
Published Date: 17 October 2018

Impact of tumor dimensions and lymph node density on the survival of patients with hypopharyngeal squamous cell carcinoma
Ye LL, Rao J, Fan XW, Ji QH, Hu CS, Ying HM
Cancer Management and Research 2018, 10:4679-4688
Published Date: 18 October 2018

Preoperative PROSTATE scoring system: a potential predictive tool for the risk of biochemical recurrence after radical prostatectomy
Zhang ZN, Luo C, Xu B, Song HF, Ma BL, Zhang Q
Cancer Management and Research 2018, 10:4671-4677
Published Date: 16 October 2018

Systematic review and meta-analysis of cancer studies evaluating diagnostic test accuracy and prognostic values: approaches to improve clinical interpretation of results
Jayaraj R, Kumarasamy C
Cancer Management and Research 2018, 10:4669-4670
Published Date: 16 October 2018


Celecoxib in breast cancer prevention and therapy
Li J, Hao Q, Cao W, Vadgama JV, Wu Y
Cancer Management and Research 2018, 10:4653-4667
Published Date: 26 October 2018

Long noncoding RNA ROR as a novel biomarker for progress and prognosis outcome in human cancer: a meta-analysis in the Asian population
Yang S, Chen J, Yu Y, Li D, Huang M, Yuan L, Yin G
Cancer Management and Research 2018, 10:4641-4652
Published Date: 15 October 2018

Advances in antitumor effects of NSAIDs
Zhang Z, Chen FL, Shang L
Cancer Management and Research 2018, 10:4631-4640
Published Date: 15 October 2018

DJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1α expression through the PI3K-AKT pathway
Zheng H, Zhou C, Lu X, Liu Q, Liu M, Chen G, Chen W, Wang S, Qiu Y
Cancer Management and Research 2018, 10:4615-4629
Published Date: 16 October 2018

CAV3.1 knockdown suppresses cell proliferation, migration and invasion of prostate cancer cells by inhibiting AKT
Hu SB, Li L, Huang W, Liu J, Lan G, Yu S, Peng L, Xie X, Yang L, Nian Y, Wang Y
Cancer Management and Research 2018, 10:4603-4614
Published Date: 15 October 2018

The role of biosimilars in value-based oncology care
Patel KB, Arantes Jr LH, Tang WY, Fung S
Cancer Management and Research 2018, 10:4591-4602
Published Date: 17 October 2018

MicroRNA-365 suppresses cell growth and invasion in esophageal squamous cell carcinoma by modulating phosphoserine aminotransferase 1
Sun C, Zhang X, Chen Y, Jia Q, Yang J, Shu Y
Cancer Management and Research 2018, 10:4581-4590
Published Date: 15 October 2018

Moderating effects of sleep duration on diabetes risk among cancer survivors: analysis of the National Health Interview Survey in the USA
Seixas AA, Gyamfi L, Newsome V, Ranger-Murdock G, Butler M, Rosenthal DM, Zizi F, Youssef I, McFarlane SI, Jean-Louis G
Cancer Management and Research 2018, 10:4575-4580
Published Date: 12 October 2018

Incidence and prognosis factors of extragonadal choriocarcinoma in males: a population-based study
Qiu J, Jia S, Li G
Cancer Management and Research 2018, 10:4565-4573
Published Date: 15 October 2018

Castleman’s disease in the HIV-endemic setting
Mahroug E, Sher-Locketz C, Desmirean M, Abayomi EA, Tomuleasa C, Grewal R
Cancer Management and Research 2018, 10:4553-4563
Published Date: 12 October 2018

Rasip1 is a RUNX1 target gene and promotes migration of NSCLC cells
Chen Y, Zhang L, Liu L, Sun S, Zhao X, Wang Y, Zhang Y, Du J, Gu L
Cancer Management and Research 2018, 10:4537-4552
Published Date: 12 October 2018

Trends in clinical features and survival of oral cavity cancer: fifty years of experience with 3,362 consecutive cases from a single institution
Chen SW, Zhang Q, Guo ZM, Chen WK, Liu WW, Chen YF, Li QL, Liu XK, Li H, Ou-Yang D, Chen WC, Fu XY, Wang XD, Yang AK, Bei JX, Song M
Cancer Management and Research 2018, 10:4523-4535
Published Date: 12 October 2018

Severe toxicity to capecitabine due to a new variant at a donor splicing site in the dihydropyrimidine dehydrogenase (DPYD) gene
García-González X, López-Tarruella S, García MI, González-Haba E, Blanco C, Salvador-Martin S, Jerez Y, Thomas F, Jarama M, Sanjurjo Sáez M, Martín M, López-Fernández LA
Cancer Management and Research 2018, 10:4517-4522
Published Date: 11 October 2018

Clinicopathologic characteristics and clinical outcomes of pure type and mixed type of tubular carcinoma of the breast: a single-institution cohort study
Zhang WW, Wu SG, Ling YH, Sun JY, Long ZQ, Hua X, Dong Y, Li FY, He ZY, Lin HX
Cancer Management and Research 2018, 10:4509-4515
Published Date: 11 October 2018

Predictive biomarkers for tumor immune checkpoint blockade
Tong M, Wang J, He W, Wang Y, Pan H, Li D, Zhang H
Cancer Management and Research 2018, 10:4501-4507
Published Date: 11 October 2018

Prognostic values of HE4 expression in patients with cancer: a meta-analysis
Dai C, Zheng Y, Li Y, Tian T, Wang M, Xu P, Deng Y, Hao Q, Wu Y, Zhai Z, Dai Z, Lyu J
Cancer Management and Research 2018, 10:4491-4500
Published Date: 10 October 2018

Clinicopathological characteristics and survival outcomes of bladder neuroendocrine carcinomas: a population-based study
Niu Q, Lu Y, Xu S, Shi Q, Guo B, Guo Z, Huang T, Wu Y, Yu J
Cancer Management and Research 2018, 10:4479-4489
Published Date: 11 October 2018

The effect of intravenous hydration strategy on plasma methotrexate clearance during intravenous high-dose methotrexate administration in pediatric oncology patients
Traivaree C, Likasitthananon N, Monsereenusorn C, Rujkijyanont P
Cancer Management and Research 2018, 10:4471-4478
Published Date: 10 October 2018

SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis
Zhang X, Zhang P, Shao M, Zang X, Zhang J, Mao F, Qian H, Xu W
Cancer Management and Research 2018, 10:4459-4470
Published Date: 10 October 2018

Confirmed value of shear wave elastography for ultrasound characterization of breast masses using a conservative approach in Chinese women: a large-size prospective multicenter trial
Lin X, Chang C, Wu CJ, Chen Q, Peng YL, Luo BM, Tang LN, Li J, Zheng JH, Zhou RH, Cui GH, Li A, Wang XM, Qian LX, Zhang JX, Wen CY, Gay J, Zhang HL, Li AH, Chen YL
Cancer Management and Research 2018, 10:4447-4458
Published Date: 11 October 2018

Response of patients with locally advanced pancreatic adenocarcinoma to high-intensity focused ultrasound treatment: a single-center, prospective, case series in China
Ji Y, Zhang Y, Zhu JQ, Zhu LL, Zhu YF, Hu K, Zhao H
Cancer Management and Research 2018, 10:4439-4446
Published Date: 9 October 2018

LINE-1 ORF-1p enhances the transcription factor activity of pregnenolone X receptor and promotes sorafenib resistance in hepatocellular carcinoma cells
Chen Y, Zeng Q, Liu X, Fu J, Zeng Z, Zhao Z, Liu Z, Bai W, Dong Z, Liu H, Lu X, Zhu Y, Lu Y
Cancer Management and Research 2018, 10:4421-4438
Published Date: 10 October 2018

Clinicopathological characteristics and prognostic factors for primary thyroid lymphoma: report on 28 Chinese patients and results of a population-based study
Chen E, Wu Q, Jin Y, Jin W, Cai Y, Wang Q, Zhang X, Wang O, Li Q, Zheng Z
Cancer Management and Research 2018, 10:4411-4419
Published Date: 10 October 2018

Importance of tumor size at diagnosis as a prognostic factor for hepatocellular carcinoma survival: a population-based study
Wu GY, Wu J, Wang BH, Zhu XL, Shi XL, Ding YT
Cancer Management and Research 2018, 10:4401-4410
Published Date: 10 October 2018

Serum miR-4530 sensitizes breast cancer to neoadjuvant chemotherapy by suppressing RUNX2
Wang XX, Ye FG, Zhang J, Li JJ, Chen QX, Lin PY, Song CG
Cancer Management and Research 2018, 10:4393-4400
Published Date: 9 October 2018

Clinicopathological characteristics and treatment outcomes of occult breast cancer: a SEER population-based study
Ge LP, Liu XY, Xiao Y, Gou ZC, Zhao S, Jiang YZ, Di GH
Cancer Management and Research 2018, 10:4381-4391
Published Date: 9 October 2018

RETRACTED ARTICLE: Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway
Guo Y, Zhang H, Xie D, Hu X, Song R, Zhu L
Cancer Management and Research 2018, 10:4371-4380
Published Date: 11 October 2018

The high pCR rate of sandwich neoadjuvant treatment in locally advanced rectal cancer may translate into a better long-term survival benefit: 5-year outcome of a Phase II clinical trial
Hu YH, Wei JW, Chang H, Xiao WW, Lin JZ, Cai MY, Cai PQ, Kong LH, Chen G, Pan ZZ, Zeng ZF, Ding PR, Gao YH
Cancer Management and Research 2018, 10:4363-4369
Published Date: 10 October 2018

LIMD1 is a survival prognostic marker of gastric cancer and hinders tumor progression by suppressing activation of YAP1
Zhang D, Li S, Yu W, Chen C, Liu T, Sun Y, Zhao Z, Liu L
Cancer Management and Research 2018, 10:4349-4361
Published Date: 9 October 2018

Predicting the response to neoadjuvant therapy for early-stage breast cancer: tumor-, blood-, and imaging-related biomarkers
Tan W, Yang M, Yang H, Zhou F, Shen W
Cancer Management and Research 2018, 10:4333-4347
Published Date: 9 October 2018

Application of fluorescein sodium in breast cancer brain-metastasis surgery

Xiao S, Zhang J, Zhu Z, Li Y, Zhong W, Chen J, Pan Z, Xia H
Cancer Management and Research 2018, 10:4325-4331
Published Date: 12 October 2018

Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway
Zhang L, Zhang WH
Cancer Management and Research 2018, 10:4311-4323
Published Date: 8 October 2018

Molecular characterization of papillary thyroid carcinoma: a potential three-lncRNA prognostic signature
You X, Yang S, Sui J, Wu W, Liu T, Xu S, Cheng Y, Kong X, Liang G, Yao Y
Cancer Management and Research 2018, 10:4297-4310
Published Date: 8 October 2018

Identification of genes and analysis of prognostic values in nonsmoking females with non-small cell lung carcinoma by bioinformatics analyses
Yang GD, Chen QY, Xiao JM, Zhang HL, Wang ZC, Lin XG
Cancer Management and Research 2018, 10:4287-4295
Published Date: 8 October 2018

Clinical significance of prognostic score based on age, tumor size, and grade in gastric cancer after gastrectomy
Lu J, Chen Y, Liu Y, Ding J, Piao Z, Liu W
Cancer Management and Research 2018, 10:4279-4286
Published Date: 8 October 2018

Abnormal microRNA expression in the course of hematological malignancies
Szymczyk A, Macheta A, Podhorecka M
Cancer Management and Research 2018, 10:4267-4277
Published Date: 8 October 2018

lncRNA LOC100132354 promotes angiogenesis through VEGFA/VEGFR2 signaling pathway in lung adenocarcinoma
Wang Y, Zhang F, Wang J, Hu L, Jiang F, Chen J, Chen J, Wang L
Cancer Management and Research 2018, 10:4257-4266
Published Date: 5 October 2018

Risk factors for delayed chemotherapy-induced nausea and vomiting with low-emetic-risk chemotherapy: a prospective, observational, multicenter study
Hayashi T, Shimokawa M, Matsuo K, Miyoshi T, Toriyama Y, Yokota C, Taniguchi J, Hanada K, Tsumagari K, Okubo N, Koutake Y, Sakata K, Kawamata Y, Goto T, Tsurusaki Y, Koyabu M
Cancer Management and Research 2018, 10:4249-4255
Published Date: 4 October 2018

Capsaicin-induced TRIB3 upregulation promotes apoptosis in cancer cells
Lin RJ, Wu IJ, Hong JY, Liu BH, Liang RY, Yuan TM, Chuang SM
Cancer Management and Research 2018, 10:4237-4248
Published Date: 4 October 2018

Survival and recurrence patterns of multifocal glioblastoma after radiation therapy
Syed M, Liermann J, Verma V, Bernhardt D, Bougatf N, Paul A, Rieken S, Debus J, Adeberg S
Cancer Management and Research 2018, 10:4229-4235
Published Date: 4 October 2018

IL-17 induces macrophages to M2-like phenotype via NF-κB
Shen J, Sun X, Pan B, Cao S, Cao J, Che D, Liu F, Zhang S, Yu Y
Cancer Management and Research 2018, 10:4217-4228
Published Date: 4 October 2018


Usefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection


Guo Y, Chen F, Cui W
Cancer Management and Research 2018, 10:4203-4216
Published Date: 4 October 2018

Knockdown of PKM2 suppresses tumor progression in human cervical cancer by modulating epithelial–mesenchymal transition via Wnt/β-catenin signaling
Lin Y, Meng F, Lu Z, Chen K, Tao Y, Ouyang Y, Cao X
Cancer Management and Research 2018, 10:4191-4202
Published Date: 4 October 2018

Prognostic factors for postoperative survival among patients with rhabdomyosarcoma of the limbs
Ren S, Wang Z, Huang X, Sun L, Shao J, Ye Z
Cancer Management and Research 2018, 10:4181-4189
Published Date: 3 October 2018

Expression of GP88 (progranulin) in serum of prostate cancer patients is associated with Gleason scores and overall survival
Greither T, Fischer K, Theil G, Marcou M, Holzhausen HJ, Weigelt K, Serrero G, Hicks D, Yue BB, Fornara P, Wullich B, Taubert H, Wach S, Lieb V
Cancer Management and Research 2018, 10:4173-4180
Published Date: 5 October 2018

Monitoring of tumor vascular normalization: the key points from basic research to clinical application
Li W, Quan Y, Li Y, Lu L, Cui M
Cancer Management and Research 2018, 10:4163-4172
Published Date: 3 October 2018

MTHFR C677T and A1298C polymorphisms and lung cancer risk in a female Chinese population
Tong W, Tong G, Jin D, Lv Q
Cancer Management and Research 2018, 10:4155-4161
Published Date: 3 October 2018

A novel gene-pair signature for relapse-free survival prediction in colon cancer
Chen P, Wang F, Zhang Z, Nie J, Liu L, Feng J, Zhou R, Wang H, Liu J, Zhao Q
Cancer Management and Research 2018, 10:4145-4153
Published Date: 3 October 2018

Prognostic value of pre- and post-operative circulating tumor cells detection in colorectal cancer patients treated with curative resection: a prospective cohort study based on ISET device
Yang C, Shi D, Wang S, Wei C, Zhang C, Xiong B
Cancer Management and Research 2018, 10:4135-4144
Published Date: 4 October 2018

The role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R
Liang ZG, Lin GX, Yu BB, Su F, Li L, Qu S, Zhu XD
Cancer Management and Research 2018, 10:4125-4134
Published Date: 2 October 2018

Programmed death ligand 1 expression in human intrahepatic cholangiocarcinoma and its association with prognosis and CD8+ T-cell immune responses
Zhu Y, Wang XY, Zhang Y, Xu D, Dong J, Zhang Z, Yi CH, Jia HL, Yang X
Cancer Management and Research 2018, 10:4113-4123
Published Date: 2 October 2018

Locoregional recurrence-associated factors and risk-adapted postmastectomy radiotherapy for breast cancer staged in cT1-2N0-1 after neoadjuvant chemotherapy
Wang X, Xu L, Yin Z, Wang D, Wang Q, Xu K, Zhao J, Zhao L, Yuan Z, Wang P
Cancer Management and Research 2018, 10:4105-4112
Published Date: 2 October 2018

Aspirin use is associated with a reduced risk of cholangiocarcinoma: a systematic review and meta-analysis
Xiong JP, Xu WY, Bian J, Huang HC, Bai Y, Xu YY, Lu X, Zhao HT
Cancer Management and Research 2018, 10:4095-4104
Published Date: 1 October 2018

The effect of coping strategy on quality of life in patients with NSCLC
Chabowski M, Jankowska-Polanska B, Lomper K, Janczak D
Cancer Management and Research 2018, 10:4085-4093
Published Date: 1 October 2018

Dietary changes in the first 3 years after breast cancer diagnosis: a prospective Chinese breast cancer cohort study
Lei Y, Ho SC, Cheng A, Kwok C, Cheung KL, He Y, Lee CI, Lee R, Yeo W
Cancer Management and Research 2018, 10:4073-4084
Published Date: 1 October 2018

Cost-effectiveness analysis of adjuvant treatment for resected pancreatic cancer in China based on the ESPAC-4 trial
Huang J, Liao W, Zhou J, Zhang P, Wen F, Wang X, Zhang M, Zhou K, Wu Q, Li Q
Cancer Management and Research 2018, 10:4065-4072
Published Date: 1 October 2018

Development and validation of an immunity-related classifier of nine chemokines for predicting recurrence in stage I-III patients with colorectal cancer after operation
Xu G, Zhou Y, Zhou F
Cancer Management and Research 2018, 10:4051-4064
Published Date: 1 October 2018

Progression and prognostic value of ECT2 in non-small-cell lung cancer and its correlation with PCNA
Bai X, Yi M, Xia X, Yu S, Zheng X, Wu K
Cancer Management and Research 2018, 10:4039-4050
Published Date: 28 September 2018

Role of exosomal small RNA in prostate cancer metastasis
Zhan F, Shen J, Wang R, Wang L, Dai Y, Zhang Y, Huang X
Cancer Management and Research 2018, 10:4029-4038
Published Date: 28 September 2018

EGFR-TKI-sensitive mutations in lung carcinomas: are they related to clinical features and CT findings?
Qin X, Gu X, Lu Y, Zhou W
Cancer Management and Research 2018, 10:4019-4027
Published Date: 1 October 2018

Young age is an independent adverse prognostic factor in early stage breast cancer: a population-based study
Zhang X, Yang J, Cai H, Ye Y
Cancer Management and Research 2018, 10:4005-4018
Published Date: 27 September 2018

An intronic genetic variation of MGMT affects enhancer activity and is associated with glioma susceptibility
Huang L, Xu W, Dai L, Yan D, Zhang S, Shi X
Cancer Management and Research 2018, 10:3995-4003
Published Date: 27 September 2018

Identification of WDR12 as a novel oncogene involved in hepatocellular carcinoma propagation
Yin Y, Zhou L, Zhan R, Zhang Q, Li M
Cancer Management and Research 2018, 10:3985-3993
Published Date: 27 September 2018

Epidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro [Erratum]
Xie B, Sun LY, Cheng YJ, Zhou J, Zheng JH, Zhang WM
Cancer Management and Research 2018, 10:3983-3984
Published Date: 26 September 2018


Benefit of adjuvant radiotherapy following narrow-margin hepatectomy in patients with intrahepatic cholangiocarcinoma that adhere to major vessels
Zheng X, Chen B, Wu JX, Jia AY, Rong WQ, Wang LM, Wu F, Zhao YT, Li YX, Wang WH
Cancer Management and Research 2018, 10:3973-3981
Published Date: 26 September 2018

Galectin-3 and β-catenin are associated with a poor prognosis in serous epithelial ovarian cancer
Liu Y, Xie L, Wang D, Li D, Xu G, Wang L, Zhou H, Yu Y, Lin Z, Lu H
Cancer Management and Research 2018, 10:3963-3971
Published Date: 26 September 2018

Villoglandular adenocarcinoma of cervix: pathologic features, clinical management, and outcome
Guo P, Liu PF, Yang JJ, Ren T, Xiang Y
Cancer Management and Research 2018, 10:3955-3961
Published Date: 26 September 2018

Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis
Zhou C, Feng X, Yuan F, Ji J, Shi M, Yu Y, Zhu Z, Zhang J
Cancer Management and Research 2018, 10:3945-3954
Published Date: 26 September 2018

KLF6-SV1 is a new prognostic biomarker in postoperative patients with non-small cell lung cancer
Zhang N, Li Z, Xiao W, Yang F, Gao W, Sun ZG
Cancer Management and Research 2018, 10:3937-3944
Published Date: 26 September 2018

Effects of controlled ovarian stimulation on toxicity of TAC chemotherapy in early breast cancer patients
de Groot S, Louwé LA, Ramautar AIE, Portielje JEA, Ogilvie AC, Batman E, Fiocco M, Kroep JR
Cancer Management and Research 2018, 10:3931-3935
Published Date: 26 September 2018

Prognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer
Yang Y, Wang D, Jin L, Wu G, Bai Z, Wang J, Yao H, Zhang Z
Cancer Management and Research 2018, 10:3911-3929
Published Date: 26 September 2018

First-line treatment strategies for newly diagnosed chronic myeloid leukemia: a network meta-analysis
Chen KK, Du TF, Wu KS, Yang W
Cancer Management and Research 2018, 10:3891-3910
Published Date: 25 September 2018

CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p
Wang S, Xue X, Wang R, Li X, Li Q, Wang Y, Xie P, Kang Y, Meng R, Feng X
Cancer Management and Research 2018, 10:3881-3890
Published Date: 25 September 2018

Incidence and distribution of advanced colorectal adenomas in patients undergoing colonoscopy for screening, surveillance, and symptoms
Kang H, Yang Y, Qiu J, Qian J, Li X
Cancer Management and Research 2018, 10:3875-3880
Published Date: 25 September 2018

Young age increases the risk of lymph node positivity in papillary thyroid cancer patients: a SEER data-based study
Wang J, Liu J, Pan H, Jiang C, Liu S, Zhu Z, Fang J, Zheng X, Hong S, Wang S
Cancer Management and Research 2018, 10:3867-3873
Published Date: 25 September 2018

CD44 is overexpressed and correlated with tumor progression in gallbladder cancer
He YT, Xue C, Yu Y, Chen JA, Chen XL, Ren F, Ren ZG, Cui GY, Sun RR
Cancer Management and Research 2018, 10:3857-3865
Published Date: 24 September 2018

Metabolic syndrome and the risk of cholangiocarcinoma: a hospital-based case–control study in China
Xiong J, Lu X, Xu W, Bai Y, Huang H, Bian J, Zhang L, Long J, Xu Y, Wang Z, Zhao H
Cancer Management and Research 2018, 10:3849-3855
Published Date: 24 September 2018

Increased derived neutrophil-to-lymphocyte ratio and Breast Imaging-Reporting and Data System classification predict poor survival in patients with non-distant metastatic HER2+ breast cancer treated with neoadjuvant chemotherapy
Li Y, Shao Y, Bai L, Zhou X
Cancer Management and Research 2018, 10:3841-3847
Published Date: 24 September 2018

Multidisciplinary therapy for scirrhous gastric cancer: a retrospective analysis and proposal of new treatment strategy
Fushida S, Kinoshita J, Oyama K, Fujimura T, Tsukada T, Yamaguchi T, Ninomiya I, Ohta T
Cancer Management and Research 2018, 10:3833-3839
Published Date: 24 September 2018

Computed tomography scan efficacy in staging gastric linitis plastica lesion: a retrospective multicentric French study

Morgant S, Artru P, Oudjit A, Lourenco N, Pasquer A, Walter T, Gornet JM, Rouquette A, Lledo G, Brezault C, Coriat R
Cancer Management and Research 2018, 10:3825-3831
Published Date: 24 September 2018

Efficacy and safety of de-escalation bone-modifying agents for cancer patients with bone metastases: a systematic review and meta-analysis
Liu C, Wang L, Liu L, Zhuang J, Tang S, Zhang TS, Zhou C, Feng F, Liu R, Zhang J, Zhang T, Gao C, Li H, Li J, Sun C
Cancer Management and Research 2018, 10:3809-3823
Published Date: 21 September 2018

Polymorphisms in AURKA and AURKB are associated with the survival of triple-negative breast cancer patients treated with taxane-based adjuvant chemotherapy
Liao Y, Liao Y, Li J, Li J, Fan Y, Xu B
Cancer Management and Research 2018, 10:3801-3808
Published Date: 21 September 2018

Ethylacetate extract from Tetrastigma hemsleyanum inhibits proliferation and induces apoptosis in HepG2 and SMMC-7721 cells
Chen S, Luo M, Ma L, Lin W
Cancer Management and Research 2018, 10:3793-3799
Published Date: 21 September 2018

Secondhand smoking increases bladder cancer risk in nonsmoking population: a meta-analysis
Yan H, Ying Y, Xie H, Li J, Wang X, He L, Jin K, Tang J, Xu X, Zheng X
Cancer Management and Research 2018, 10:3781-3791
Published Date: 21 September 2018

Spotlight on cabozantinib for previously untreated advanced renal cell carcinoma: evidence to date
Bersanelli M, Leonardi F, Buti S
Cancer Management and Research 2018, 10:3773-3780
Published Date: 21 September 2018

The impact of biopsy sampling errors and the quality of surgical margins on local recurrence and survival in chondrosarcoma
Hodel S, Laux CJ, Farei-Campagna J, Götschi T, Bode-Lesniewska B, Müller DA
Cancer Management and Research 2018, 10:3765-3771
Published Date: 21 September 2018

S100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism
Zhao C, Lu E, Hu X, Cheng H, Zhang JA, Zhu X
Cancer Management and Research 2018, 10:3753-3764
Published Date: 20 September 2018

Emerging clinical significance of claudin-7 in colorectal cancer: a review
Wang K, Xu C, Li WJ, Ding L
Cancer Management and Research 2018, 10:3741-3752
Published Date: 20 September 2018

Stereotactic radiosurgery for vestibular schwannomas
Braunstein S, Ma L
Cancer Management and Research 2018, 10:3733-3740
Published Date: 20 September 2018

An expression signature model to predict lung adenocarcinoma-specific survival
Shi X, Tan H, Le X, Xian H, Li X, Huang K, Luo VY, Liu Y, Wu Z, Mo HY, Chen AM, Liang Y, Zhang J
Cancer Management and Research 2018, 10:3717-3732
Published Date: 24 September 2018

A model combining TNM stage and tumor size shows utility in predicting recurrence among patients with hepatocellular carcinoma after resection
Zhang Y, Chen S, Liu L, Yang X, Cai S, Yun J
Cancer Management and Research 2018, 10:3707-3715
Published Date: 20 September 2018

Low expression of VSIG4 is associated with poor prognosis in hepatocellular carcinoma patients with hepatitis B infection
Zhu S, Tan W, Li W, Zhou R, Wu X, Chen X, Li W, Shang C, Chen Y
Cancer Management and Research 2018, 10:3697-3705
Published Date: 20 September 2018

Decreased expression of TRIM21 indicates unfavorable outcome and promotes cell growth in breast cancer
Zhou WB, Zhang YY, Zhong CN, Hu JT, Hu H, Zhou DX, Cao MQ
Cancer Management and Research 2018, 10:3687-3696
Published Date: 20 September 2018

Impact of CT slice thickness on volume and dose evaluation during thoracic cancer radiotherapy
Luo H, He Y, Jin F, Yang D, Liu X, Ran X, Wang Y
Cancer Management and Research 2018, 10:3679-3686
Published Date: 20 September 2018

Gemcitabine and docetaxel as second-line chemotherapy in elderly patients with metastatic urothelial carcinoma: a retrospective analysis
Naiki T, Iida K, Etani T, Nagai T, Tanaka Y, Sugiyama Y, Ando R, Hamamoto S, Banno R, Nagata D, Kawai N, Yasui T
Cancer Management and Research 2018, 10:3669-3677
Published Date: 18 September 2018

Nomogram predicts survival benefit for non-metastatic esophageal cancer patients who underwent preoperative radiotherapy
Xie K, Liu S, Liu J
Cancer Management and Research 2018, 10:3657-3668
Published Date: 18 September 2018

No association between tumor laterality and cardiac-related mortality in breast cancer patients after radiotherapy: a population-based study
Li WH, Zhang ZG, Huang ZR, Zhang W, Li ZB, Qi ZQ
Cancer Management and Research 2018, 10:3649-3656
Published Date: 18 September 2018

Efficacy and safety of lenalidomide for the treatment of acute myeloid leukemia: a systematic review and meta-analysis
Xie CH, Wei M, Yang FY, Wu FZ, Chen L, Wang JK, Liu Q, Huang JX
Cancer Management and Research 2018, 10:3637-3648
Published Date: 18 September 2018

Predictive factors for the efficacy of the second taxane treatment in patients with advanced cancer
Imai H, Saijo K, Komine K, Kawamura Y, Hiraide S, Umegaki S, Okada Y, Ouchi K, Sato Y, Takahashi M, Takahashi S, Shirota H, Takahashi M, Ishioka C
Cancer Management and Research 2018, 10:3629-3636
Published Date: 17 September 2018

Development of a risk grading system to identify patients with acute promyelocytic leukemia at high risk of early death
Zhang Y, Hou W, Wang P, Hou J, Yang H, Zhao H, Jin B, Sun J, Cao F, Zhao Y, Li H, Ge F, Fu J, Zhou J
Cancer Management and Research 2018, 10:3619-3627
Published Date: 17 September 2018

Elevated red blood cell distribution width predicts poor prognosis in patients with oral squamous cell carcinoma
Ge W, Xie J, Chang L
Cancer Management and Research 2018, 10:3611-3618
Published Date: 17 September 2018

Neutrophil–lymphocyte ratio is a predictor of prognosis in patients with castration-resistant prostate cancer: a meta-analysis
Wang Z, Peng S, Xie H, Guo L, Jiang N, Shang Z, Niu Y
Cancer Management and Research 2018, 10:3599-3610
Published Date: 17 September 2018

Perivascular cell coverage of intratumoral vasculature is a predictor for bevacizumab efficacy in metastatic colorectal cancer
Jiang C, Huang Y, Lu J, Yang Y, Rao H, Zhang B, He W, Xia L
Cancer Management and Research 2018, 10:3589-3597
Published Date: 17 September 2018

miR-300 rs12894467 polymorphism may be associated with susceptibility to primary lung cancer in the Chinese Han population
Liu Z, Lin Y, Kang S, Xu Q, Xiong W, Cai L, He F
Cancer Management and Research 2018, 10:3579-3588
Published Date: 17 September 2018

Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer
Mao Y, Feng Q, Zheng P, Yang L, Liu T, Xu Y, Zhu D, Chang W, Ji M, Ren L, Wei Y, He G, Xu J
Cancer Management and Research 2018, 10:3569-3577
Published Date: 17 September 2018

PLNR≤20% may be a benefit from PORT for patients with IIIA-N2 NSCLC: a large population-based study
Shang X, Li Z, Lin J, Wang H, Wang Z
Cancer Management and Research 2018, 10:3561-3567
Published Date: 17 September 2018

Epidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro
Xie B, Sun LY, Cheng YJ, Zhou J, Zheng JH, Zhang WM
Cancer Management and Research 2018, 10:3551-3560
Published Date: 13 September 2018

Identification of key candidate genes and small molecule drugs in cervical cancer by bioinformatics strategy
Tang X, Xu YC, Lu L, Jiao Y, Liu JJ, Wang LL, Zhao HB
Cancer Management and Research 2018, 10:3533-3549
Published Date: 13 September 2018

Expressions and prognostic values of the E2F transcription factors in human breast carcinoma
Liu ZL, Bi XW, Liu PP, Lei DX, Wang Y, Li ZM, Jiang WQ, Xia Y
Cancer Management and Research 2018, 10:3521-3532
Published Date: 13 September 2018

Enhanced recovery after surgery decreases intestinal recovery time and pain intensity in patients undergoing curative gastrectomy
Ji W, Chandoo A, Guo X, You T, Shao Z, Zheng K, Wang J, Bi J, Smith FG, Tucker ON, Shen X
Cancer Management and Research 2018, 10:3513-3520
Published Date: 13 September 2018

CD8+ tumor-infiltrating lymphocytes as a novel prognostic biomarker in lung sarcomatoid carcinoma, a rare subtype of lung cancer
Chen J, He Q, Liu J, Xiao Y, Xiao C, Chen K, Xie D, Zhang X
Cancer Management and Research 2018, 10:3505-3511
Published Date: 13 September 2018

Letter to the editor “Prognostic value of microRNAs in colorectal cancer: a meta-analysis”
Jayaraj R, Kumarasamy C, Gothandam KM
Cancer Management and Research 2018, 10:3501-3503
Published Date: 13 September 2018

Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity
Asby DJ, Killick-Cole CL, Boulter LJ, Singleton WGB, Asby CA, Wyatt MJ, Barua NU, Bienemann AS, Gill SS
Cancer Management and Research 2018, 10:3483-3500
Published Date: 12 September 2018

Splenectomy during cytoreductive surgery in epithelial ovarian cancer
Sun H, Bi X, Cao D, Yang J, Wu M, Pan L, Huang H, Chen G, Shen K
Cancer Management and Research 2018, 10:3473-3482
Published Date: 12 September 2018

Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer
Wang N, Guo H, Dong Z, Chen Q, Zhang X, Shen W, Bao Y, Wang X
Cancer Management and Research 2018, 10:3463-3471
Published Date: 12 September 2018

Assessment of functional variants and expression of long noncoding RNAs in vitamin D receptor signaling in breast cancer
Kholghi Oskooei V, Geranpayeh L, Omrani MD, Ghafouri-Fard S
Cancer Management and Research 2018, 10:3451-3462
Published Date: 12 September 2018

Overexpression of kinesin family member 20A is associated with unfavorable clinical outcome and tumor progression in epithelial ovarian cancer
Li H, Zhang W, Sun X, Chen J, Li Y, Niu C, Xu B, Zhang Y
Cancer Management and Research 2018, 10:3433-3450
Published Date: 12 September 2018

Checkpoint molecule PD-1-assisted CD8+ T lymphocyte count in tumor microenvironment predicts overall survival of patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors
Yao J, Xi W, Zhu Y, Wang H, Hu X, Guo J
Cancer Management and Research 2018, 10:3419-3431
Published Date: 11 September 2018

Comparison and validation of the value of preoperative inflammation marker-based prognostic scores in resectable pancreatic ductal adenocarcinoma
Ye S, Bai L
Cancer Management and Research 2018, 10:3405-3417
Published Date: 11 September 2018

Prognostic value of EGFR and KRAS in resected non-small cell lung cancer: a systematic review and meta-analysis
Zhang SM, Zhu QG, Ding XX, Lin S, Zhao J, Guan L, Li T, He B, Zhang HQ
Cancer Management and Research 2018, 10:3393-3404
Published Date: 10 September 2018

Identification of an eight-gene prognostic signature for lung adenocarcinoma
Li S, Xuan Y, Gao B, Sun X, Miao S, Lu T, Wang Y, Jiao W
Cancer Management and Research 2018, 10:3383-3392
Published Date: 10 September 2018

The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients
Zhang P, Zhang M, Han R, Zhang K, Ding H, Liang C, Zhang L
Cancer Management and Research 2018, 10:3371-3381
Published Date: 10 September 2018

RBBP6 expressional effects on cell proliferation and apoptosis in breast cancer cell lines with distinct p53 statuses
Motadi LR, Lekganyane MM, Moela P
Cancer Management and Research 2018, 10:3357-3369
Published Date: 10 September 2018

Associations of sirtuins with clinicopathological parameters and prognosis in non–small cell lung cancer
Gong J, Wang H, Lou W, Wang G, Tao H, Wen H, Liu Y, Xie Q
Cancer Management and Research 2018, 10:3341-3356
Published Date: 10 September 2018

Significance of circulating tumor cells in osteosarcoma patients treated by neoadjuvant chemotherapy and surgery
Wu ZJ, Tan JC, Qin X, Liu B, Yuan ZC
Cancer Management and Research 2018, 10:3333-3339
Published Date: 10 September 2018

Musculoskeletal complication in kaposiform hemangioendothelioma without Kasabach–Merritt phenomenon: clinical characteristics and management

Ji Y, Yang K, Chen S, Peng S, Lu G, Liu X
Cancer Management and Research 2018, 10:3325-3331
Published Date: 7 September 2018

Can bone scans guide therapy with radium-223 dichloride for prostate cancer bone metastases?

Gayed I, Salama V, Dawood L, Canfield S, Wan D, Cai C, Joseph U, Amato R
Cancer Management and Research 2018, 10:3317-3324
Published Date: 7 September 2018

The role of external beam radiotherapy for hepatocellular carcinoma patients with lymph node metastasis: a meta-analysis of observational studies
Rim CH, Kim CY, Yang DS, Yoon WS
Cancer Management and Research 2018, 10:3305-3315
Published Date: 6 September 2018

Comprehensive analysis of clinical utility of three-dimensional ultrasound for benign and malignant breast masses
Fu J, Li Y, Li N, Li Z
Cancer Management and Research 2018, 10:3295-3303
Published Date: 6 September 2018

FOXA1 is upregulated in glioma and promotes proliferation as well as cell cycle through regulation of cyclin D1 expression
Zhang C, Yang M, Li Y, Tang S, Sun X
Cancer Management and Research 2018, 10:3283-3293
Published Date: 6 September 2018

Combination of recurrent oral aphthae and dry eye syndrome may constitute an independent risk factor for oral cavity cancer in elderly women
Qin L, Kao YW, Lin YL, Peng BY, Deng WP, Chen TM, Lin KC, Yuan KSP, Wu ATH, Shia BC, Wu SY
Cancer Management and Research 2018, 10:3273-3281
Published Date: 5 September 2018

Prognostic value of minichromosome maintenance mRNA expression in early-stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy
Liao X, Han C, Wang X, Huang K, Yu T, Yang C, Huang R, Liu Z, Han Q, Peng T
Cancer Management and Research 2018, 10:3255-3271
Published Date: 5 September 2018

A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer
Xu K, Liu B, Ma Y, Xu B, Xing X
Cancer Management and Research 2018, 10:3245-3254
Published Date: 4 September 2018

Prediction of central lymph node metastasis in papillary thyroid microcarcinoma according to clinicopathologic factors and thyroid nodule sonographic features: a case-control study
Jin WX, Ye DR, Sun YH, Zhou XF, Wang OC, Zhang XH, Cai YF
Cancer Management and Research 2018, 10:3237-3243
Published Date: 4 September 2018

Cervical cancer screening using the Cervista high-risk human papillomavirus test: opportunistic screening of a hospital-based population in Fujian province, China
Ruan GY, Song YY, Dong BH, Mao XD, Lin F, Kang YF, Xu SX, Chen XJ, Wu QB, Sun PM
Cancer Management and Research 2018, 10:3227-3235
Published Date: 4 September 2018

Surgical intervention may be a therapeutic option for NSCLC patients with AJCC stage IV: a large population-based study
Wang H, Yan L, Li C, Wang Z
Cancer Management and Research 2018, 10:3219-3226
Published Date: 4 September 2018

Treatment strategies and predicting prognoses in elderly patients with breast cancer
Wang Z, Zhou Z, Li W, Wang W, Xie X, Liu J, Song Y, Dang C, Zhang H
Cancer Management and Research 2018, 10:3207-3218
Published Date: 4 September 2018

Clinical value of carcinoembryonic antigen for predicting the incidence of brain metastases and survival in small cell lung cancer patients treated with prophylactic cranial irradiation
Guo D, Jing W, Zhu H, Li MH, Zou B, Zhang Y, Fu L, Kong L, Yue J, Yu J
Cancer Management and Research 2018, 10:3199-3205
Published Date: 4 September 2018

Correlation of variable repeat number in the neck regions of DC-SIGN and DC-SIGNR with susceptibility to nasopharyngeal carcinoma in a Chinese population
Ning S, Yao M, Wu Y, Zhou X, Zhong C, Yan K, Wei Z, Xie Y
Cancer Management and Research 2018, 10:3193-3198
Published Date: 4 September 2018

Trend in relative survival in squamous cervical cancer by decade from 1983 to 2012: a period analysis
Wu J, Sun H, Wang S, Yan Y, Sun F, Li Y, Yang G, Ma H
Cancer Management and Research 2018, 10:3177-3191
Published Date: 3 September 2018

Prognostic value of tumor burden in nasopharyngeal carcinoma
Chen CB, Fei ZD, Huang CX, Ding JM, Chen LS
Cancer Management and Research 2018, 10:3169-3175
Published Date: 3 September 2018

ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling
Liu B, Xing X, Li X, Guo Q, Xu T, Xu K
Cancer Management and Research 2018, 10:3159-3168
Published Date: 3 September 2018

Methyl jasmonate enhances the radiation sensitivity of esophageal carcinoma cells by inhibiting the 11-ketoprostaglandin reductase activity of AKR1C3
Li XY, Hong X, Gao XS, Gu XB, Xiong W, Zhao J, Yu HL, Cui M, Xie M, Bai Y, Sun SQ
Cancer Management and Research 2018, 10:3149-3158
Published Date: 31 August 2018

Association between lncRNA CASC8 polymorphisms and the risk of cancer: a meta-analysis
Cui Z, Gao M, Yin Z, Yan L, Cui L
Cancer Management and Research 2018, 10:3141-3148
Published Date: 31 August 2018

Prognostic value of serum alkaline phosphatase in the survival of prostate cancer: evidence from a meta-analysis
Li D, Lv H, Hao X, Hu B, Song Y
Cancer Management and Research 2018, 10:3125-3139
Published Date: 30 August 2018


Probe-based three-dimensional confocal laser endomicroscopy of brain tumors: technical note


Belykh E, Patel AA, Miller EJ, Bozkurt B, Yağmurlu K, Woolf EC, Scheck AC, Eschbacher JM, Nakaji P, Preul MC
Cancer Management and Research 2018, 10:3109-3123
Published Date: 30 August 2018

Predictive value of carcinoembryonic antigen and carbohydrate antigen 19-9 related to downstaging to stage 0–I after neoadjuvant chemoradiotherapy in locally advanced rectal cancer
Song JY, Huang XX, Chen ZH, Chen MQ, Lin QL, Li AC, Chen YG, Xu BH
Cancer Management and Research 2018, 10:3101-3108
Published Date: 30 August 2018

Clinical utility of fulvestrant in the treatment of breast cancer: a report on the emerging clinical evidence
Rocca A, Maltoni R, Bravaccini S, Donati C, Andreis D
Cancer Management and Research 2018, 10:3083-3099
Published Date: 30 August 2018

A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction
Dai X, Zhang J, Guo G, Cai Y, Cui R, Yin C, Liu W, Vinothkumar R, Zhang T, Liang G, Zhang X
Cancer Management and Research 2018, 10:3069-3082
Published Date: 29 August 2018

Silencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib
Chen Z, Jiang ZK, Zhang WZ, He BX
Cancer Management and Research 2018, 10:3057-3067
Published Date: 29 August 2018

Analysis of potential genes associated with primary cilia in bladder cancer
Du E, Lu C, Sheng F, Li C, Li H, Ding N, Chen Y, Zhang T, Yang K, Xu Y
Cancer Management and Research 2018, 10:3047-3056
Published Date: 29 August 2018

Quantitative assessment of aberrant P16INK4a methylation in ovarian cancer: a meta-analysis based on literature and TCGA datasets
Ruan J, Xu P, Fan W, Deng Q, Yu M
Cancer Management and Research 2018, 10:3033-3046
Published Date: 29 August 2018

Prognostic value of aspartate aminotransferase to platelet ratio index as a noninvasive biomarker in patients with hepatocellular carcinoma: a meta-analysis
Zhang Y, Zhang X
Cancer Management and Research 2018, 10:3023-3032
Published Date: 29 August 2018

The predictive value of cumulative toxicity for quality of life in patients with metastatic colorectal cancer during first-line palliative chemotherapy
Schuurhuizen CSEW, Verheul HMW, Braamse AMJ, Buffart LM, Bloemendal HJ, Dekker J, Konings IRHM
Cancer Management and Research 2018, 10:3015-3021
Published Date: 29 August 2018

A cumulative score based on preoperative fibrinogen and the neutrophil–lymphocyte ratio to predict outcomes in resectable gastric cancer
Liu X, Liu Z, Lin E, Chen Y, Sun X, Zhou Z
Cancer Management and Research 2018, 10:3007-3014
Published Date: 28 August 2018

Distinct prognostic values of mRNA expression of glutathione peroxidases in non–small cell lung cancer
Liu K, Jin M, xiao L, Liu H, Wei S
Cancer Management and Research 2018, 10:2997-3005
Published Date: 28 August 2018

Elevated serum LAMC2 is associated with lymph node metastasis and predicts poor prognosis in penile squamous cell carcinoma
Zhou Q, Deng C, Chen J, Huang K, Liu T, Yao K, Liu ZW, Qin Z, Li Y, Guo S, Ye Y, Zhou F, Huang W, Liu R, Han H
Cancer Management and Research 2018, 10:2983-2995
Published Date: 28 August 2018

Treatment outcomes of ureteral stenting for malignant extrinsic ureteral obstruction: a comparison between polymeric and metallic stents
Asakawa J, Iguchi T, Tamada S, Ninomiya N, Kato M, Yamasaki T, Nakatani T
Cancer Management and Research 2018, 10:2977-2982
Published Date: 28 August 2018

Relationship between IGF2BP2 and IGFBP3 polymorphisms and susceptibility to non-small-cell lung cancer: a case–control study in Eastern Chinese Han population
Chen S, Qiu H, Liu C, Wang Y, Tang W, Kang M
Cancer Management and Research 2018, 10:2965-2975
Published Date: 28 August 2018

Diagnostic potential of methylated DAPK in brushing samples of nasopharyngeal carcinoma
Zhang J, Shen Z, Liu H, Liu S, Shu W
Cancer Management and Research 2018, 10:2953-2964
Published Date: 28 August 2018

Computational analysis of mRNA expression profiles identifies a novel triple-biomarker model as prognostic predictor of stage II and III colorectal adenocarcinoma patients
Cheng X, Hu M, Chen C, Hou D
Cancer Management and Research 2018, 10:2945-2952
Published Date: 28 August 2018

Incidence of bone metastasis and factors contributing to its development and prognosis in newly diagnosed renal cell carcinoma: a population-based study
Guo Q, Zhang C, Guo X, Tao F, Xu Y, Feng G, Han X, Ren Z, Zhang H, Zhang P, Wang X, Wang G
Cancer Management and Research 2018, 10:2935-2944
Published Date: 28 August 2018

TNM-PNI: a novel prognostic scoring system for patients with gastric cancer and curative D2 resection
Gao ZM, Wang RY, Deng P, Ding P, Zheng C, Hou B, Li K
Cancer Management and Research 2018, 10:2925-2933
Published Date: 28 August 2018

Efficacy and safety of TAS-102 in refractory metastatic colorectal cancer: a meta-analysis
Chen D, Wu YS, Lin H, Wang Y, Li L, Zhang T
Cancer Management and Research 2018, 10:2915-2924
Published Date: 28 August 2018

Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells
Geng Y, Liu J, Xie Y, Jiang H, Zuo K, Li T, Liu Z
Cancer Management and Research 2018, 10:2905-2914
Published Date: 28 August 2018

The role of CCN4/WISP-1 in the cancerous phenotype
Nivison MP, Meier KE
Cancer Management and Research 2018, 10:2893-2903
Published Date: 27 August 2018

Long-term oncologic outcomes of papillary thyroid microcarcinoma according to the presence of clinically apparent lymph node metastasis: a large retrospective analysis of 5,348 patients
Choi JB, Lee WK, Lee SG, Ryu H, Lee CR, Kang SW, Jeong JJ, Nam KH, Lee EJ, Chung WY, Jo YS, Lee J
Cancer Management and Research 2018, 10:2883-2891
Published Date: 27 August 2018

Differences in clinical characteristics and mutational pattern between synchronous and metachronous colorectal liver metastases
Zheng P, Ren L, Feng Q, Zhu D, Chang W, He G, Ji M, Jian M, Lin Q, Yi T, Wei Y, Xu J
Cancer Management and Research 2018, 10:2871-2881
Published Date: 27 August 2018

Using LC–MS/MS-based targeted proteomics to monitor the pattern of ABC transporters expression in the development of drug resistance
Meng F, Zou L, Zhang T, Jiang L, Ding Y, Yu P, Peng J
Cancer Management and Research 2018, 10:2859-2870
Published Date: 23 August 2018

Gfi-1 promotes proliferation of human cervical carcinoma via targeting of FBW7 ubiquitin ligase expression
Cai H, Zhang F, Li Z
Cancer Management and Research 2018, 10:2849-2857
Published Date: 23 August 2018

Tissue transglutaminase 2 expression is epigenetically regulated in human lung cancer cells and prevents reactive oxygen species-induced apoptosis
Lee MY, Wu MF, Cherng SH, Chiu LY, Yang TY, Sheu GT
Cancer Management and Research 2018, 10:2835-2848
Published Date: 23 August 2018

MicroRNA-200b expression level is negatively associated with pathological grading in human gliomas
Kong X, Gong S, Yan T, Yang Y
Cancer Management and Research 2018, 10:2825-2834
Published Date: 24 August 2018

Treatment options for refractory/relapsed multiple myeloma: an updated evidence synthesis by network meta-analysis
Luo XW, Du XQ, Li JL, Liu XP, Meng XY
Cancer Management and Research 2018, 10:2817-2823
Published Date: 21 August 2018

The association of HIF-1α expression with clinicopathological significance in prostate cancer: a meta-analysis
Huang M, Du H, Zhang L, Che H, Liang C
Cancer Management and Research 2018, 10:2809-2816
Published Date: 21 August 2018

LncRNA TINCR is associated with clinical progression and serves as tumor suppressive role in prostate cancer
Dong L, Ding H, Li Y, Xue D, Liu Y
Cancer Management and Research 2018, 10:2799-2807
Published Date: 20 August 2018

Prognostic value of inflammation-based prognostic index in patients with nasopharyngeal carcinoma: a propensity score matching study
Oei RW, Ye L, Kong F, Du C, Zhai R, Xu T, Shen C, Wang X, He X, Kong L, Hu C, Ying H
Cancer Management and Research 2018, 10:2785-2797
Published Date: 17 August 2018

The expression profile and clinical application potential of hsa_circ_0000711 in colorectal cancer
Li J, Ni S, Zhou C, Ye M
Cancer Management and Research 2018, 10:2777-2784
Published Date: 17 August 2018

G-CSF associates with neurogenesis and predicts prognosis and sensitivity to chemotherapy in pancreatic ductal adenocarcinoma
Zhang L, Tao L, Guo L, Zhan J, Yuan C, Ma Z, Jiang B, Xiu D
Cancer Management and Research 2018, 10:2767-2775
Published Date: 17 August 2018

High Spy1 expression predicts poor prognosis in colorectal cancer
Jin Q, Liu G, Bao L, Ma Y, Qi H, Yun Z, Dai Y, Zhang S
Cancer Management and Research 2018, 10:2757-2765
Published Date: 16 August 2018

Prevalence and characteristics of colonic adenoma in mainland China
Hong W, Dong L, Stock S, Basharat Z, Zippi M, Zhou M
Cancer Management and Research 2018, 10:2743-2755
Published Date: 16 August 2018

Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil
Kurata T, Fushida S, Kinoshita J, Oyama K, Yamaguchi T, Okazaki M, Miyashita T, Tajima H, Ninomiya I, Ohta T
Cancer Management and Research 2018, 10:2729-2742
Published Date: 15 August 2018

lncRNA PVT1 identified as an independent biomarker for prognosis surveillance of solid tumors based on transcriptome data and meta-analysis
Chen X, Yang Y, Cao Y, Wu C, Wu S, Su Z, Jin H, Wang D, Zhang G, Fan W, Lin J, Zeng Y, Hu D
Cancer Management and Research 2018, 10:2711-2727
Published Date: 16 August 2018

Nonsteroidal anti-inflammatory drugs, especially aspirin, are linked to lower risk and better survival of hepatocellular carcinoma: a meta-analysis
Tao Y, Li Y, Liu X, Deng Q, Yu Y, Yang Z
Cancer Management and Research 2018, 10:2695-2709
Published Date: 15 August 2018

A network-based signature to predict the survival of non-smoking lung adenocarcinoma
Mao Q, Zhang L, Zhang Y, Dong G, Yang Y, Xia W, Chen B, Ma W, Hu J, Jiang F, Xu L
Cancer Management and Research 2018, 10:2683-2693
Published Date: 16 August 2018

Dose-escalated radiotherapy improved survival for esophageal cancer patients with a clinical complete response after standard-dose radiotherapy with concurrent chemotherapy
Zhang W, Luo YJ, Wang XL, Han GH, Wang P, Yuan W, Dai SB
Cancer Management and Research 2018, 10:2675-2682
Published Date: 14 August 2018

Proximal shift of colorectal cancer with increasing age in different ethnicities
Yang L, Xiong Z, He W, Xie K, Liu S, Kong P, Jiang C, Guo G, Xia L
Cancer Management and Research 2018, 10:2663-2673
Published Date: 15 August 2018

IL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression
Al Obeed OA, Vaali-Mohammed MA, Alkhayal KA, Bin Traiki TA, Zubaidi AM, Arafah M, Harris RA, Khan Z, Abdulla MH
Cancer Management and Research 2018, 10:2653-2661
Published Date: 5 September 2018

Use of FLT3 inhibitors in acute myeloid leukemia remission induction or salvage therapy: systematic review and meta-analysis
Yang M, Zhao J, Liu T, Yang X, Wei H, Xu W, Xiao J
Cancer Management and Research 2018, 10:2635-2652
Published Date: 14 August 2018

Upregulated expression of miR-421 is associated with poor prognosis in non-small-cell lung cancer
Li Y, Cui X, Li Y, Zhang T, Li S
Cancer Management and Research 2018, 10:2627-2633
Published Date: 13 August 2018

AP-2α expression in papillary thyroid carcinoma predicts tumor progression and poor prognosis
Wu HR, Zhang J
Cancer Management and Research 2018, 10:2615-2625
Published Date: 13 August 2018

Risk factors for gastric intraepithelial neoplasia in Chinese adults: a case–control study
Yu Y, Fang C, Peng C, Shen S, Xu G, Sun Q, Li L, Su C, Zou X
Cancer Management and Research 2018, 10:2605-2613
Published Date: 13 August 2018

Association of IL-8 gene promoter -251 A/T and IL-18 gene promoter -137 G/C polymorphisms with head and neck cancer risk: a comprehensive meta-analysis
Wang Z, Gao ZM, Huang HB, Sun LS, Sun AQ, Li K
Cancer Management and Research 2018, 10:2589-2604
Published Date: 10 August 2018

Short- and long-term outcomes of laparoscopic hepatectomy for colorectal liver metastases in elderly patients
Yue M, Li S, Yan G, Li C, Kang Z
Cancer Management and Research 2018, 10:2581-2587
Published Date: 10 August 2018

Clinical value of circulating ESR1 mutations for patients with metastatic breast cancer: a meta-analysis
Zhang K, Hong R, Xu F, Xia W, Kaping L, Qin G, Zheng Q, Lu Q, Shi YX, Yuan ZY, Wang SS
Cancer Management and Research 2018, 10:2573-2580
Published Date: 14 August 2018

E2F1 induces LSINCT5 transcriptional activity and promotes gastric cancer progression by affecting the epithelial-mesenchymal transition
Qi P, Lin W, Zhang M, Huang D, Ni S, Zhu X, Bai Q, Sheng W, Du X, Zhou X
Cancer Management and Research 2018, 10:2563-2571
Published Date: 10 August 2018

The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials
Guo XX, Wu HL, Shi HY, Su L, Zhang X
Cancer Management and Research 2018, 10:2553-2562
Published Date: 10 August 2018

Genome-scale analysis to identify prognostic microRNA biomarkers in patients with early stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy
Liao X, Wang X, Huang K, Yang C, Yu T, Han C, Zhu G, Su H, Huang R, Peng T
Cancer Management and Research 2018, 10:2537-2551
Published Date: 10 August 2018

Novel endocrine therapeutic strategy in endometrial carcinoma targeting estrogen-related receptor α by XCT790 and siRNA
Sun PM, Mao XD, Gao M, Huang MM, Chen LL, Ruan GY, Huang WY, Braicu EI, Sehouli J
Cancer Management and Research 2018, 10:2521-2535
Published Date: 10 August 2018

Adjuvant chemotherapy for stage II colon cancer: who really needs it
Yang Y, Yang Y, Yang H, Wang F, Wang HH, Chen Q, Liu Y, Li AY, Zhang QA
Cancer Management and Research 2018, 10:2509-2520
Published Date: 8 August 2018

Association of low skeletal muscle index with increased systematic inflammatory responses and interferon γ-induced protein 10 levels in patients with colon cancer
He WZ, Yang QX, Xie JY, Kong PF, Hu WM, Yang L, Yang YZ, Xie QK, Jiang C, Yin CX, Guo GF, Qiu HJ, Zhang B, Xia LP
Cancer Management and Research 2018, 10:2499-2507
Published Date: 7 August 2018

Biological and clinical influences of NPM1 in acute myeloid leukemia patients with DNMT3A mutations
Yang X, Shi J, Zhang X, Zhang G, Zhang J, Yang S, Wang J, Ke X, Fu L
Cancer Management and Research 2018, 10:2489-2497
Published Date: 7 August 2018


Current landscape and future directions of biomarkers for predicting responses to immune checkpoint inhibitors
Zhu Y, Zhao F, Li Z, Yu J
Cancer Management and Research 2018, 10:2475-2488
Published Date: 7 August 2018

Bone metastasis predicts poor prognosis of patients with brain metastases from colorectal carcinoma post aggressive treatment
Duan H, He ZQ, Guo CC, Li JH, Wang J, Zhu Z, Sai K, Chen ZP, Jiang XB, Mou YG
Cancer Management and Research 2018, 10:2467-2474
Published Date: 6 August 2018

Clinical and biological implications of IDH1/2 in acute myeloid leukemia with DNMT3Amut
Zhang XP, Shi JL, Zhang JL, Yang XR, Zhang GQ, Yang SY, Wang J, Ke XY, Fu L
Cancer Management and Research 2018, 10:2457-2466
Published Date: 6 August 2018

Model of lymph node metastasis posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma
Luo Y, Xu XC, Shen J, Shi JJ, Lu S, He W, Lei JY, Luo DC
Cancer Management and Research 2018, 10:2449-2455
Published Date: 6 August 2018

Tracking steps in oncology: the time is now
Purswani JM, Ohri N, Champ C
Cancer Management and Research 2018, 10:2439-2447
Published Date: 3 August 2018

Overview of advances in vasculogenic mimicry – a potential target for tumor therapy
Ge H, Luo H
Cancer Management and Research 2018, 10:2429-2437
Published Date: 2 August 2018

TMEM17 promotes malignant progression of breast cancer via AKT/GSK3β signaling
Zhao Y, Song K, Zhang Y, Xu H, Zhang X, Wang L, Fan C, Jiang G, Wang E
Cancer Management and Research 2018, 10:2419-2428
Published Date: 2 August 2018

Pretreatment NRS-2002 scores combined with hematologic inflammation markers are independent prognostic factors in patients with resectable thoracic esophageal squamous cell carcinoma
Guo XW, Liu YC, Gao F, Ji SJ, Zhou JY, Ji L, Zhou SB
Cancer Management and Research 2018, 10:2409-2418
Published Date: 2 August 2018

Surgical significance and efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in patients with primary lung adenosquamous carcinoma
Zhang C, Yang H, Lang B, Yu X, Xiao P, Zhang D, Fan L, Zhang X
Cancer Management and Research 2018, 10:2401-2407
Published Date: 2 August 2018

LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21
Xiao L, Wang Y, Liang W, Liu L, Pan N, Deng H, Li L, Zou C, Chan FL, Zhou Y
Cancer Management and Research 2018, 10:2389-2400
Published Date: 1 August 2018

Lack of association between the risk of prostate cancer and vitamin D receptor Bsm I polymorphism: a meta-analysis of 27 published studies
Kang S, Zhao Y, Wang L, Liu J, Chen X, Liu X, Shi Z, Gao W, Cao F
Cancer Management and Research 2018, 10:2377-2387
Published Date: 1 August 2018

Decreased expression of COLEC10 predicts poor overall survival in patients with hepatocellular carcinoma
Zhang B, Wu H
Cancer Management and Research 2018, 10:2369-2375
Published Date: 1 August 2018

Intermittent androgen deprivation therapy: recommendations to improve the management of patients with prostate cancer following the GRADE approach
Bonfill X, Arevalo-Rodriguez I, Martínez García L, Quintana MJ, Buitrago-García D, Lobos Urbina D, Cordero JA
Cancer Management and Research 2018, 10:2357-2367
Published Date: 2 August 2018

Establishment and external validation of a prognostic model for predicting disease-free survival and risk stratification in breast cancer patients treated with neoadjuvant chemotherapy
Lai JG, Wang HL, Peng JW, Chen PX, Pan ZH
Cancer Management and Research 2018, 10:2347-2356
Published Date: 1 August 2018

Bioinformatic analysis of four miRNAs relevant to metastasis-regulated processes in endometrial carcinoma
Zhu L, Shu Z, Shun X
Cancer Management and Research 2018, 10:2337-2346
Published Date: 1 August 2018

Targeting energy metabolism to eliminate cancer cells
Shahruzaman SH, Fakurazi S, Maniam S
Cancer Management and Research 2018, 10:2325-2335
Published Date: 31 July 2018

Human leukocyte antigen gene polymorphisms are associated with systemic inflammation in hepatitis B virus-related hepatocellular carcinoma
Wu XL, Li ZY, Bi XY, Zhao H, Zhao JJ, Zhou JG, Han Y, Huang Z, Zhang YF, Cai JQ
Cancer Management and Research 2018, 10:2315-2324
Published Date: 31 July 2018

P–TNM staging system for colon cancer: combination of P-stage and AJCC TNM staging system for improving prognostic prediction and clinical management
Liu Q, Luo D, Cai S, Li Q, Li X
Cancer Management and Research 2018, 10:2303-2314
Published Date: 31 July 2018

Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer
Pan JH, Zhou H, Zhu SB, Huang JL, Zhao XX, Ding H, Pan YL
Cancer Management and Research 2018, 10:2289-2301
Published Date: 1 August 2018

Pooling analysis on prognostic value of PHH3 expression in cancer patients
Hao Q, Dai C, Deng Y, Xu P, Tian T, Lin S, Wang M, Liu K, Song D, Wu Y, Guo Y, Dai Z
Cancer Management and Research 2018, 10:2279-2288
Published Date: 30 July 2018

FAM98A promotes proliferation of non-small cell lung cancer cells via the P38-ATF2 signaling pathway
Zheng R, Liu Q, Wang T, Wang L, Zhang Y
Cancer Management and Research 2018, 10:2269-2278
Published Date: 27 July 2018

Disparities of age-based cancer-specific survival improvement with various clinicopathologic characteristics for kidney cancer
Liu K, Wang P, Zhu X, Bei Y, Zheng Z, Yan S
Cancer Management and Research 2018, 10:2259-2268
Published Date: 27 July 2018

MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer
Yang S, Sun Z, Zhou Q, Wang W, Wang G, Song J, Li Z, Zhang Z, Chang Y, Xia K, Liu J, Yuan W
Cancer Management and Research 2018, 10:2249-2257
Published Date: 26 July 2018

PRAF2 expression indicates unfavorable clinical outcome in hepatocellular carcinoma
Wang CH, Liu LL, Liao DZ, Zhang MF, Fu J, Lu SX, Chen SL, Wang H, Cai SH, Zhang CZ, Zhang HZ, Yun JP
Cancer Management and Research 2018, 10:2241-2248
Published Date: 25 July 2018

Prognostic value of subcutaneous adipose tissue volume in hepatocellular carcinoma treated with transcatheter intra-arterial therapy

Kobayashi T, Kawai H, Nakano O, Abe S, Kamimura H, Sakamaki A, Kamimura K, Tsuchiya A, Takamura M, Yamagiwa S, Terai S
Cancer Management and Research 2018, 10:2231-2239
Published Date: 25 July 2018

Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology
Kaliszewski K, Diakowska D, Wojtczak B, Forkasiewicz Z
Cancer Management and Research 2018, 10:2223-2229
Published Date: 23 July 2018

Profiles of differentially expressed circRNAs in esophageal and breast cancer
Shi P, Sun J, He B, Song H, Li Z, Kong W, Wang J, Wang JM, Xue H
Cancer Management and Research 2018, 10:2207-2221
Published Date: 23 July 2018

Bevacizumab combined with chemotherapy vs single-agent therapy in recurrent glioblastoma: evidence from randomized controlled trials
Chen Z, Xu N, Zhao C, Xue T, Wu X, Wang Z
Cancer Management and Research 2018, 10:2193-2205
Published Date: 23 July 2018

Prognostic implications of circulating Epstein–Barr virus DNA for extranodal natural killer/T-cell lymphoma, nasal type: a meta-analysis
Chen RW, Wang C, Zhou Y, Wen B
Cancer Management and Research 2018, 10:2183-2192
Published Date: 20 July 2018

Disclosure of cancer diagnosis in China: the incidence, patients’ situation, and different preferences between patients and their family members and related influence factors
Liu Y, Yang J, Huo D, Fan H, Gao Y
Cancer Management and Research 2018, 10:2173-2181
Published Date: 23 July 2018

Prognostic value of primary tumor surgery in minor salivary-gland carcinoma patients with distant metastases at diagnosis: first evidence from a SEER-based study
Shi X, Huang NS, Shi RL, Wei WJ, Wang YL, Ji QH
Cancer Management and Research 2018, 10:2163-2172
Published Date: 20 July 2018

Preoperative circulating FPR and CCF score are promising biomarkers for predicting clinical outcome of stage II–III colorectal cancer patients
Sun F, Peng HX, Gao QF, Li SQ, Zhang J, Chen QG, Jiang YH, Zhang L, Wang XZ, Ying HQ
Cancer Management and Research 2018, 10:2151-2161
Published Date: 19 July 2018

Treatment-related adverse effects with pazopanib, sorafenib and sunitinib in patients with advanced soft tissue sarcoma: a pooled analysis
Que Y, Liang Y, Zhao JJ, Ding Y, Peng RQ, Guan YX, Zhang X
Cancer Management and Research 2018, 10:2141-2150
Published Date: 19 July 2018

Diagnostic and prognostic value of microRNAs in cholangiocarcinoma: a systematic review and meta-analysis
Sun C, Zhu J, Wu B, Chen J, Zhu Z, Cai P, Guo W, Gu Z, Wang J, Huang S
Cancer Management and Research 2018, 10:2125-2139
Published Date: 18 July 2018

Higher frequency of occult lymph node metastasis in clinical N0 pulmonary adenocarcinoma with ALK rearrangement
Seto K, Kuroda H, Yoshida T, Sakata S, Mizuno T, Sakakura N, Hida T, Yatabe Y, Sakao Y
Cancer Management and Research 2018, 10:2117-2124
Published Date: 18 July 2018

Differential diagnostic value of 18F-FDG PET/CT for benign and malignant vertebral compression fractures: comparison with magnetic resonance imaging

He X, Zhao L, Guo X, Zhao L, Wu J, Huang J, Sun L, Xie C, Chen H
Cancer Management and Research 2018, 10:2105-2115
Published Date: 18 July 2018

Right- and left-sided stage III colon cancers present different prognostic outcomes of oxaliplatin-based adjuvant chemotherapy after curative resection
Peng J, Li C, Wang F, Zhang H, Xiao W, Li H, Lu Z, Pan Z, Wu X, Zhang R
Cancer Management and Research 2018, 10:2095-2103
Published Date: 17 July 2018

Lymph node ratio as a valuable prognostic factor for patients with colorectal liver-only metastasis undergoing curative resection
Deng YX, Peng JH, Zhao YJ, Sui QQ, Zhao RX, Lu ZH, Qiu MZ, Lin JZ, Pan ZZ
Cancer Management and Research 2018, 10:2083-2094
Published Date: 17 July 2018

Nebivolol effect on doxorubicin-induced cardiotoxicity in breast cancer
Cochera F, Dinca D, Bordejevic DA, Citu IM, Mavrea AM, Andor M, Trofenciuc M, Tomescu MC
Cancer Management and Research 2018, 10:2071-2081
Published Date: 16 July 2018

Quantifying the prognostic significance of microRNA-17/17-5P in cancers: a meta-analysis based on published studies
Duan F, Yang Y, Liu W, Zhao J, Song X, Li L, Li F
Cancer Management and Research 2018, 10:2055-2069
Published Date: 17 July 2018

Long-term survival effect of the interval between mastectomy and radiotherapy in locally advanced breast cancer
Zhang WW, Wu SG, Sun JY, Li FY, He ZY
Cancer Management and Research 2018, 10:2047-2054
Published Date: 16 July 2018

Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer
Jin S, Cao S, Grigorev A, Li J, Meng Q, Wang C, Feng M, Hu J, Jiang F, Yu Y
Cancer Management and Research 2018, 10:2031-2046
Published Date: 16 July 2018

Predictive significance of preoperative CT findings for suboptimal cytoreduction in advanced ovarian cancer: a meta-analysis
Hu TWY, Nie D, Gou JH, Li ZY
Cancer Management and Research 2018, 10:2019-2030
Published Date: 16 July 2018

Evidence-based complementary treatment of pancreatic cancer: a review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins, metformin, curcumin, and aspirin
Bigelsen S
Cancer Management and Research 2018, 10:2003-2018
Published Date: 13 July 2018

Comparison of survival outcomes of locally advanced breast cancer patients receiving post-mastectomy radiotherapy with and without immediate breast reconstruction: a population-based analysis
Wu SG, Zhang WW, Sun JY, Lin Q, He ZY
Cancer Management and Research 2018, 10:1993-2002
Published Date: 13 July 2018

The miR-200 family: multiple effects on gliomas
Peng L, Fu J, Ming Y
Cancer Management and Research 2018, 10:1987-1992
Published Date: 13 July 2018

Concurrent weekly single cisplatin vs triweekly cisplatin alone with radiotherapy for treatment of locally advanced cervical cancer: a meta-analysis
Zhu J, Ji S, Hu Q, Chen Q, Liu Z, Wu J, Gu K
Cancer Management and Research 2018, 10:1975-1985
Published Date: 12 July 2018

Neuropilin-1 expression is associated with lymph node metastasis in breast cancer tissues
Seifi-Alan M, Shams R, Bandehpour M, Mirfakhraie R, Ghafouri-Fard S
Cancer Management and Research 2018, 10:1969-1974
Published Date: 11 July 2018


Prognostic significance of lymph node metastasis and lymphadenectomy in early-stage ovarian carcinosarcoma


Wang WP, Li N, Zhang YY, Gao YT, Sun YC, Ge L, Wu LY
Cancer Management and Research 2018, 10:1959-1968
Published Date: 10 July 2018

Direct comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma
Chen H, Zhang Y, Li S, Li N, Chen Y, Zhang B, Qu C, Ding H, Huang J, Dai M
Cancer Management and Research 2018, 10:1947-1958
Published Date: 10 July 2018

The prognostic significance of carcinoma-associated fibroblasts and tumor-associated macrophages in nasopharyngeal carcinoma
Yu Y, Ke L, Lv X, Ling Y, Lu J, Liang H, Qiu W, Huang X, Liu G, Li W, Guo X, Xia W, Xiang Y
Cancer Management and Research 2018, 10:1935-1946
Published Date: 9 July 2018

Recurrence risk after preoperative biopsy in patients with resected early-stage non-small-cell lung cancer: a retrospective study
Hu CP, Jiang J, Li YY, Zhang CF, Zhang WX, Jiang HH, Gao Y, Zhuang W, Lei KB, Tang Y, Wan RJ
Cancer Management and Research 2018, 10:1927-1934
Published Date: 6 July 2018

Prognostic significance of Ki67 expression and the derived neutrophil–lymphocyte ratio in nasopharyngeal carcinoma
Zhao L, Chen H, Hu B, Zhang H, Lin Q
Cancer Management and Research 2018, 10:1919-1926
Published Date: 5 July 2018

Benefit from the inclusion of surgery in the treatment of patients with stage III pancreatic cancer: a propensity-adjusted, population-based SEER analysis
Wang L, Cheng CS, Chen L, Chen Z
Cancer Management and Research 2018, 10:1907-1918
Published Date: 5 July 2018

Safety and efficacy of denosumab in the treatment of pulmonary metastatic giant cell tumor of bone

Luo Y, Tang F, Wang Y, Zhou Y, Min L, Zhang W, Shi R, Duan H, Tu C
Cancer Management and Research 2018, 10:1901-1906
Published Date: 5 July 2018

Modern management for brain metastasis patients using stereotactic radiosurgery: literature review and the authors’ gamma knife treatment experiences
Higuchi Y, Yamamoto M, Serizawa T, Aiyama H, Sato Y, Barfod BE
Cancer Management and Research 2018, 10:1889-1899
Published Date: 5 July 2018

Prognostic and predictive value of the macroscopic growth pattern in patients undergoing curative resection of colorectal cancer: a single-institution retrospective cohort study of 4,080 Chinese patients
Li X, Zhao Q, An B, Qi J, Wang W, Zhang D, Li Z, Qin C
Cancer Management and Research 2018, 10:1875-1887
Published Date: 4 July 2018

The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance
Okazaki M, Fushida S, Tsukada T, Kinoshita J, Oyama K, Miyashita T, Ninomiya I, Harada S, Ohta T
Cancer Management and Research 2018, 10:1865-1874
Published Date: 4 July 2018

Clinical usefulness of 18F-FDG PET/CT for the detection of distant metastases in patients with non-small cell lung cancer at initial staging: a meta-analysis
Yu B, Zhu X, Liang Z, Sun Y, Zhao W, Chen K
Cancer Management and Research 2018, 10:1859-1864
Published Date: 4 July 2018


Recent advances in antiemetics: new formulations of 5HT3-receptor antagonists
Gilmore J, D'Amato S, Griffith N, Schwartzberg L
Cancer Management and Research 2018, 10:1827-1857
Published Date: 3 July 2018

Downregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/β-catenin signaling pathways
Chen W, You J, Zheng Q, Zhu Y
Cancer Management and Research 2018, 10:1817-1826
Published Date: 2 July 2018

Polymorphisms in MYCN gene and neuroblastoma risk in Chinese children: a 3-center case–control study
Zhou H, Zhuo Z, Chen S, Zhao J, Mo Y, Zhang J, He J, Ruan J
Cancer Management and Research 2018, 10:1807-1816
Published Date: 2 July 2018

High expression of ALDOA and DDX5 are associated with poor prognosis in human colorectal cancer
Dai L, Pan G, Liu X, Huang J, Jiang Z, Zhu X, Gan X, Xu Q, Tan N
Cancer Management and Research 2018, 10:1799-1806
Published Date: 29 June 2018

CYP17 polymorphisms are associated with decreased risk of breast cancer in Chinese Han women: a case–control study
Yang P, Wang M, Tian T, Feng Y, Zheng Y, Yang T, Li H, Lin S, Xu P, Deng Y, Hao Q, Li N, Guan F, Dai Z
Cancer Management and Research 2018, 10:1791-1798
Published Date: 3 July 2018

Decreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma
Xiao YB, Cai SH, Liu LL, Yang X, Yun JP
Cancer Management and Research 2018, 10:1781-1789
Published Date: 26 June 2018

Prognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis
Guo H, Huang S, Li S, Yu H, Wu S, Zhou X
Cancer Management and Research 2018, 10:1763-1779
Published Date: 27 June 2018

A panel containing PD-1, IL-2Rα, IL-10, and CA15-3 as a biomarker to discriminate breast cancer from benign breast disease
Liu C, Sun B, Xu B, Meng X, Li L, Cong Y, Liu J, Wang Q, Xuan L, Song Q, Wu S
Cancer Management and Research 2018, 10:1749-1761
Published Date: 26 June 2018

Disparities in survival for right-sided vs. left-sided colon cancers in young patients: a study based on the Surveillance, Epidemiology, and End Results database (1990–2014)
Wang Y, Yang L, Zhou M, Shen L, Zhang J, Deng W, Liang L, Hu R, Yang W, Yao Y, Zhang Z
Cancer Management and Research 2018, 10:1735-1747
Published Date: 26 June 2018

The prognosis and effects of local treatment strategies for orbital embryonal rhabdomyosarcoma: a population-based study
Tang LY, Zhang MX, Lu DH, Chen YX, Liu ZG, Wu SG
Cancer Management and Research 2018, 10:1727-1734
Published Date: 25 June 2018

The prognostic value of differentially expressed CYP3A subfamily members for hepatocellular carcinoma
Yu T, Wang X, Zhu G, Han C, Su H, Liao X, Yang C, Qin W, Huang K, Peng T
Cancer Management and Research 2018, 10:1713-1726
Published Date: 25 June 2018

A retrospective study of concurrent chemoradiotherapy plus S-1 adjuvant chemotherapy on curative effect for treatment of patients with N3 stage nasopharyngeal carcinoma
Zhang S, Zhou L, Huang X, Lin S
Cancer Management and Research 2018, 10:1705-1711
Published Date: 25 June 2018

The prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis
Zhang L, Wu B, Zha Z, Zhao H, Feng Y
Cancer Management and Research 2018, 10:1687-1703
Published Date: 22 June 2018

Cervical lymph node metastases in salivary gland adenoid cystic carcinoma: a systematic review and meta-analysis
Ning C, Zhao T, Wang Z, Li D, Kou Y, Huang S
Cancer Management and Research 2018, 10:1677-1685
Published Date: 22 June 2018

Cancer risk assessment in modern radiotherapy workflow with medical big data
Jin F, Luo HL, Zhou J, He YN, Liu XF, Zhong MS, Yang H, Li C, Li QC, Huang X, Tian XM, Qiu D, He GL, Yin L, Wang Y
Cancer Management and Research 2018, 10:1665-1675
Published Date: 22 June 2018

miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case–control study involving 2,740 participants
Chen Y, Tang W, Liu C, Lin J, Wang Y, Zhang S, Chen G, Zheng X
Cancer Management and Research 2018, 10:1657-1664
Published Date: 25 June 2018

Decreased expression of TRPV1 in renal cell carcinoma: association with tumor Fuhrman grades and histopathological subtypes
Wu YY, Liu XY, Zhuo DX, Huang HB, Zhang FB, Liao SF
Cancer Management and Research 2018, 10:1647-1655
Published Date: 22 June 2018

The homogeneous and heterogeneous risk factors for the morbidity and prognosis of bone metastasis in patients with prostate cancer
Guo X, Zhang C, Guo Q, Xu Y, Feng G, Li L, Han X, Lu F, Ma Y, Wang X, Wang G
Cancer Management and Research 2018, 10:1639-1646
Published Date: 22 June 2018

Pioglitazone use in patients with diabetes and risk of bladder cancer: a systematic review and meta-analysis
Yan H, Xie H, Ying Y, Li J, Wang X, Xu X, Zheng X
Cancer Management and Research 2018, 10:1627-1638
Published Date: 22 June 2018

Role of key players in paradigm shifts of prostate cancer bone metastasis

Sohail A, Sherin L, Butt SI, Javed S, Li Z, Iqbal S, Be'g OA
Cancer Management and Research 2018, 10:1619-1626
Published Date: 21 June 2018

Optimal management of resected gastric cancer
Giampieri R, Del Prete M, Cantini L, Baleani MG, Bittoni A, Maccaroni E, Berardi R
Cancer Management and Research 2018, 10:1605-1618
Published Date: 21 June 2018

An increased number of negative lymph nodes is associated with a higher immune response and longer survival in colon cancer patients
He WZ, Xie QK, Hu WM, Kong PF, Yang L, Yang YZ, Jiang C, Yin CX, Qiu HJ, Zhang HZ, Zhang B, Xia LP
Cancer Management and Research 2018, 10:1597-1604
Published Date: 18 June 2018

INHBA upregulation correlates with poorer prognosis in patients with esophageal squamous cell carcinoma
Lyu S, Jiang C, Xu R, Huang Y, Yan S
Cancer Management and Research 2018, 10:1585-1596
Published Date: 18 June 2018

Synaptopodin-2 plays an important role in the metastasis of breast cancer via PI3K/Akt/mTOR pathway
Xia E, Zhou X, Bhandari A, Zhang X, Wang O
Cancer Management and Research 2018, 10:1575-1583
Published Date: 18 June 2018

Knowledge, attitude, and practice toward the daily management of PICC in critically ill cancer patients discharged from intensive care units
Chen J, Zhao H, Xia Z, Zhang Y, Lv X, Zhou X, Dong X, Li J, Jiang H, Huang Y, Huang H
Cancer Management and Research 2018, 10:1565-1574
Published Date: 18 June 2018

Expression of 4E-BP1 and phospho-4E-BP1 correlates with the prognosis of patients with clear cell renal carcinoma
Li F, Wang Q, Xiong X, Wang CY, Liu X, Liao ZQ, Li K, Xie B, Lin Y
Cancer Management and Research 2018, 10:1553-1563
Published Date: 15 June 2018

Comparison of NSAIDs activity in COX-2 expressing and non-expressing 2D and 3D pancreatic cancer cell cultures
Čeponytė U, Paškevičiūtė M, Petrikaitė V
Cancer Management and Research 2018, 10:1543-1551
Published Date: 15 June 2018

A nomogram to predict overall survival for biliary tract cancer
Song W, Zhu Z, Wu Q, Lv C, Wang Y, Chen L, Miao D
Cancer Management and Research 2018, 10:1535-1541
Published Date: 14 June 2018

Multifocality is associated with central neck lymph node metastases in papillary thyroid microcarcinoma
Zheng W, Wang K, Wu J, Wang W, Shang J
Cancer Management and Research 2018, 10:1527-1533
Published Date: 14 June 2018

Fertility preservation in Hodgkin’s lymphoma patients that undergo targeted molecular therapies: an important step forward from the chemotherapy era
Traila A, Dima D, Achimas-Cadariu P, Micu R
Cancer Management and Research 2018, 10:1517-1526
Published Date: 13 June 2018

A two-microRNA signature as a diagnostic and prognostic marker of pancreatic adenocarcinoma
Yu Y, Feng X, Cang S
Cancer Management and Research 2018, 10:1507-1515
Published Date: 13 June 2018

Role of palliative radiotherapy in unresectable intrahepatic cholangiocarcinoma: population-based analysis with propensity score matching
Shao F, Qi W, Meng FT, Qiu L, Huang Q
Cancer Management and Research 2018, 10:1497-1506
Published Date: 13 June 2018

Genetic polymorphisms in the TERT gene and susceptibility to non-small cell lung cancer in a Chinese Han population
Li C, Wang X, Li Y, Zhang X, Sun M, Liu S, Sun L, Shi L, Yao Y
Cancer Management and Research 2018, 10:1487-1495
Published Date: 11 June 2018

Expression and clinical significance of autophagic protein LC3B and EMT markers in gastric cancer
Wang JY, Wu T, Ma W, Li S, Jing WJ, Ma J, Chen DM, Guo XJ, Nan KJ
Cancer Management and Research 2018, 10:1479-1486
Published Date: 11 June 2018

Poor prognosis and SATB1 overexpression in solid tumors: a meta-analysis
Wang S, Zeng J, Xiao R, Xu G, Liu G, Xiong D, Ye Y, Chen B, Wang H, Luo Q, Huang Z
Cancer Management and Research 2018, 10:1471-1478
Published Date: 8 June 2018

Extramedullary hematopoiesis secondary to malignant solid tumors: a case report and literature review

Bao Y, Liu Z, Guo M, Li B, Sun X, Wang L
Cancer Management and Research 2018, 10:1461-1470
Published Date: 8 June 2018

LncRNAs and EGFRvIII sequestered in TEPs enable blood-based NSCLC diagnosis
Luo CL, Xu ZG, Chen H, Ji J, Wang YH, Hu W, Wang K, Zhang WW, Yuan CH, Wang FB
Cancer Management and Research 2018, 10:1449-1459
Published Date: 8 June 2018

Notch signaling pathway mediates Doxorubicin-driven apoptosis in cancers
Huang Z, Lin S, Long C, Zhou X, Fan Y, Kuang X, He J, Ning J, Zhang H, Zhang Q, Shen H
Cancer Management and Research 2018, 10:1439-1448
Published Date: 8 June 2018

Influence of TS (rs34743033) and RUNX1 (rs2014300) gene polymorphisms on survival outcomes of fluorouracil-based chemotherapy in Chinese advanced gastric cancer patients
Han R, Wei J, Zhang H, Su X, Chu X, Chen Y, Gong Y, Wang X, Shi J, Chen J
Cancer Management and Research 2018, 10:1429-1437
Published Date: 6 June 2018

Concurrent chemoradiotherapy versus radiotherapy alone for locoregionally advanced nasopharyngeal carcinoma in the era of intensity-modulated radiotherapy: a meta-analysis
He Y, Guo T, Guan H, Wang J, Sun Y, Peng X
Cancer Management and Research 2018, 10:1419-1428
Published Date: 6 June 2018

Cystectomy for bladder cancer in elderly patients is not associated with increased 30- and 90-day mortality or readmission, length of stay, and cost: propensity score matching using a population database
Lin WY, Wu CT, Chen MF, Chang YH, Lin CL, Kao CH
Cancer Management and Research 2018, 10:1413-1418
Published Date: 31 May 2018

Prognostic value and clinical significance of long noncoding RNA CASC2 in human malignancies: a meta-analysis
Cai J, Zuo X, Chen Z, Zhao W, Zhu Y, Zhang Z, Ye X
Cancer Management and Research 2018, 10:1403-1412
Published Date: 31 May 2018

Combined microwave ablation and minimally invasive open decompression for the management of thoracic metastasis in breast cancer

Liu B, Yuan Z, Wei CY
Cancer Management and Research 2018, 10:1397-1401
Published Date: 31 May 2018

Performance status dynamics during treatment with nab-paclitaxel plus gemcitabine versus gemcitabine alone for metastatic pancreatic cancer
Chiorean EG, Von Hoff D, Wan Y, Margunato-Debay S, Botteman M, Goldstein D
Cancer Management and Research 2018, 10:1389-1396
Published Date: 31 May 2018

Polymorphism in lncRNA AC008392.1 and its interaction with smoking on the risk of lung cancer in a Chinese population
Lv X, Cui Z, Li H, Li J, Yang Z, Bi Y, Gao M, Zhou B, Yin Z
Cancer Management and Research 2018, 10:1377-1387
Published Date: 30 May 2018

Tumor-infiltrating lymphocyte as a prognostic biomarker in stage IV colorectal cancer should take into account the metastatic status and operation modality
Xie QK, He WZ, Hu WM, Yang L, Jiang C, Kong PF, Yang YZ, Yang Q, Zhang HZ, Zhang B, Xia LP
Cancer Management and Research 2018, 10:1365-1375
Published Date: 30 May 2018

Age distribution and age-related outcomes of olfactory neuroblastoma: a population-based analysis
Yin ZZ, Wang YY, Wu YM, Zhang XM, Wang FM, Wang PG, Tao Z, Yuan ZY
Cancer Management and Research 2018, 10:1359-1364
Published Date: 29 May 2018

Clinical effect of MUC1 and its relevance to BRAF V600E mutation in papillary thyroid carcinoma: a case–control study
Li Q, Jin W, Jin Y, Zheng Z, Zhou X, Wang Q, Ye D, Sun Y, Zhang X, Wang O, Chen E, Cai Y
Cancer Management and Research 2018, 10:1351-1358
Published Date: 29 May 2018

Association of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis
Dong ZY, Zheng L, Liu W, Wang C
Cancer Management and Research 2018, 10:1341-1349
Published Date: 25 May 2018

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer
Xie L, Lin C, Zhang Q, Piao H, Bigner DD, Zhang Z, Bao X
Cancer Management and Research 2018, 10:1329-1340
Published Date: 24 May 2018

Matching-adjusted indirect treatment comparison of ribociclib and palbociclib in HR+, HER2− advanced breast cancer
Tremblay G, Chandiwana D, Dolph M, Hearnden J, Forsythe A, Monaco M
Cancer Management and Research 2018, 10:1319-1327
Published Date: 22 May 2018

Clinical analysis of four serum tumor markers in 458 patients with ovarian tumors: diagnostic value of the combined use of HE4, CA125, CA19-9, and CEA in ovarian tumors
Chen F, Shen J, Wang J, Cai P, Huang Y
Cancer Management and Research 2018, 10:1313-1318
Published Date: 22 May 2018

Association of FGFR2 and PI3KCA genetic variants with the risk of breast cancer in a Chinese population
Wang Y, Zhang H, Lin M, Wang Y
Cancer Management and Research 2018, 10:1305-1311
Published Date: 21 May 2018

Stereotactic body radiation therapy plus induction or adjuvant chemotherapy for early stage but medically inoperable pancreatic cancer: A propensity score-matched analysis of a prospectively collected database
Zhu X, Li F, Liu W, Shi D, Ju X, Cao YS, Shen Y, Cao F, Qing S, Fang F, Jia Z, Zhang H
Cancer Management and Research 2018, 10:1295-1304
Published Date: 21 May 2018

Associated factors for oral health problems in a sample of Saudi cancer patients
Yenugadhati N, Albalawi AN, Qureshey AT, Qureshey ET, Al-Jahdali H, Jazieh AR, Ahmed AE
Cancer Management and Research 2018, 10:1285-1293
Published Date: 21 May 2018

Screening differential circular RNA expression profiles reveal that hsa_circ_0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma
Chen DW, Zhang CY, Lin JM, Song XY, Wang HY
Cancer Management and Research 2018, 10:1275-1283
Published Date: 18 May 2018

Severe cutaneous adverse reactions induced by targeted anticancer therapies and immunotherapies

Chen CB, Wu MY, Ng CY, Lu CW, Wu J, Kao PH, Yang CK, Peng MT, Huang CY, Chang WC, Hui RCY, Yang CH, Yang SF, Chung WH, Su SC
Cancer Management and Research 2018, 10:1259-1273
Published Date: 17 May 2018

The location, histologic type, and stage of lung cancer are associated with bleeding during endobronchial biopsy
Wang S, Ye Q, Tu J, Song Y
Cancer Management and Research 2018, 10:1251-1257
Published Date: 17 May 2018

Expression and significance of RRBP1 in esophageal carcinoma
Wang L, Wang M, Zhang M, Li X, Zhu Z, Wang H
Cancer Management and Research 2018, 10:1243-1249
Published Date: 17 May 2018

Dichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer
Lu X, Zhou D, Hou B, Liu QX, Chen Q, Deng XF, Yu ZB, Dai JG, Zheng H
Cancer Management and Research 2018, 10:1231-1241
Published Date: 16 May 2018

Role of Lactobacillus in cervical cancer
Yang X, Da M, Zhang W, Qi Q, Zhang C, Han S
Cancer Management and Research 2018, 10:1219-1229
Published Date: 16 May 2018

Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA
Zhang R, Chen B, Tong X, Wang Y, Wang C, Jin J, Tian P, Li W
Cancer Management and Research 2018, 10:1209-1218
Published Date: 16 May 2018

Incidental thyroid carcinoma in surgery-treated hyperthyroid patients with Graves’ disease: a systematic review and meta-analysis of cohort studies
Jia Q, Li X, Liu Y, Li L, Kwong JSW, Ren K, Jiang Y, Sun X, Tian H, Li S
Cancer Management and Research 2018, 10:1201-1207
Published Date: 21 May 2018

Prognostic factors for survival among patients with primary bone sarcomas of small bones
Wang Z, Li S, Li Y, Lin N, Huang X, Liu M, Pan WB, Yan XB, Sun LL, Li HY, Li BH, Qu H, Wu Y, Lin P, Ye ZM
Cancer Management and Research 2018, 10:1191-1199
Published Date: 14 May 2018

Preoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients
Shang Z, Wang J, Wang X, Yan H, Cui B, Jia C, Wang Q, Cui X, Li J, Ou T
Cancer Management and Research 2018, 10:1177-1190
Published Date: 14 May 2018

Overexpression of chloride channel-3 predicts unfavorable prognosis and promotes cellular invasion in gastric cancer
Peng J, Chen W, Chen J, Yuan Y, Zhang J, He Y
Cancer Management and Research 2018, 10:1163-1175
Published Date: 14 May 2018

The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer
Zheng C, Li X, Qian B, Feng N, Gao S, Zhao Y, Zhou B
Cancer Management and Research 2018, 10:1155-1162
Published Date: 14 May 2018

MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project
Tagliabue E, Gandini S, Bellocco R, Maisonneuve P, Newton-Bishop J, Polsky D, Lazovich D, Kanetsky PA, Ghiorzo P, Gruis NA, Landi MT, Menin C, Fargnoli MC, García-Borrón JC, Han J, Little J, Sera F, Raimondi S
Cancer Management and Research 2018, 10:1143-1154
Published Date: 14 May 2018

Decreased survival in patients with carcinoma of axillary tail versus upper outer quadrant breast cancers: a SEER population-based study
Gou ZC, Liu XY, Xiao Y, Zhao S, Jiang YZ, Shao ZM
Cancer Management and Research 2018, 10:1133-1141
Published Date: 14 May 2018

Do additional cores from cancer-suspicious lesions on transrectal ultrasound improve prostate cancer detection including index tumors over 12-core systematic biopsy?
Jo JK, Hong SK, Byun SS, Lee SE, Jeong SJ
Cancer Management and Research 2018, 10:1125-1131
Published Date: 10 May 2018

Blockage of store-operated Ca2+ entry antagonizes Epstein–Barr virus-promoted angiogenesis by inhibiting Ca2+ signaling-regulated VEGF production in nasopharyngeal carcinoma
Ye J, Huang J, He Q, Zhao W, Zhou X, Zhang Z, Li Y, Wei J, Zhang J
Cancer Management and Research 2018, 10:1115-1124
Published Date: 10 May 2018

A review of soft-tissue sarcomas: translation of biological advances into treatment measures
Hoang NT, Acevedo LA, Mann MJ, Tolani B
Cancer Management and Research 2018, 10:1089-1114
Published Date: 10 May 2018

Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway
Hodroj MH, Jardaly A, Abi Raad S, Zouein A, Rizk S
Cancer Management and Research 2018, 10:1079-1088
Published Date: 10 May 2018

Orbital solitary fibrous tumor: a clinicopathologic study from a Chinese tertiary hospital with a literature review

Shen J, Li H, Feng S, Cui H
Cancer Management and Research 2018, 10:1069-1078
Published Date: 9 May 2018

Survival outcomes of radical prostatectomy and external beam radiotherapy in clinically localized high-risk prostate cancer: a population-based, propensity score matched study
Gu X, Gao X, Cui M, Xie M, Ma M, Qin S, Li X, Qi X, Bai Y, Wang D
Cancer Management and Research 2018, 10:1061-1067
Published Date: 8 May 2018

Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape
Garbar C, Mascaux C, Merrouche Y, Bensussan A
Cancer Management and Research 2018, 10:1051-1059
Published Date: 4 May 2018

Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population
Ye X, Wang X, Shang L, Zhu G, Su H, Han C, Qin W, Li G, Peng T
Cancer Management and Research 2018, 10:1037-1050
Published Date: 4 May 2018

Genetic variants in the exon region of versican predict survival of patients with resected early-stage hepatitis B virus-associated hepatocellular carcinoma
Liu X, Han C, Liao X, Yu L, Zhu G, Su H, Qin W, Lu S, Ye X, Peng T
Cancer Management and Research 2018, 10:1027-1036
Published Date: 4 May 2018

Is progression-free survival a more relevant endpoint than overall survival in first-line HR+/HER2− metastatic breast cancer?
Forsythe A, Chandiwana D, Barth J, Thabane M, Baeck J, Shor A, Tremblay G
Cancer Management and Research 2018, 10:1015-1025
Published Date: 4 May 2018

Co-existence of BRAFV600E and TERT promoter mutations in papillary thyroid carcinoma is associated with tumor aggressiveness, but not with lymph node metastasis
Ren HY, Shen YF, Hu DX, He W, Zhou J, Cao YJ, Mao Y, Dou Y, Xiong W, Xiao Q, Zhang YH, Su XL
Cancer Management and Research 2018, 10:1005-1013
Published Date: 3 May 2018

MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells
Chai L, Kang XJ, Sun ZZ, Zeng MF, Yu SR, Ding Y, Liang JQ, Li TT, Zhao J
Cancer Management and Research 2018, 10:989-1003
Published Date: 3 May 2018

Preoperative neutrophil-to-lymphocyte ratio as a prognostic predictor after curative-intent surgery for hepatocellular carcinoma: experience from a developing country
Galun D, Bogdanovic A, Kovac Djokic J, Bulajic P, Loncar Z, Zuvela M
Cancer Management and Research 2018, 10:977-988
Published Date: 4 May 2018

ITGA7 functions as a tumor suppressor and regulates migration and invasion in breast cancer
Bhandari A, Xia E, Zhou Y, Guan Y, Xiang J, Kong L, Wang Y, Yang F, Wang O, Zhang X
Cancer Management and Research 2018, 10:969-976
Published Date: 1 May 2018

Genome-wide association pathway analysis to identify candidate single nucleotide polymorphisms and molecular pathways associated with TP53 expression status in HBV-related hepatocellular carcinoma
Liao X, Yu L, Liu X, Han C, Yu T, Qin W, Yang C, Zhu G, Su H, Peng T
Cancer Management and Research 2018, 10:953-967
Published Date: 1 May 2018

Highly elevated soluble Tim-3 levels correlate with increased hepatocellular carcinoma risk and poor survival of hepatocellular carcinoma patients in chronic hepatitis B virus infection
Li F, Li N, Sang J, Fan X, Deng H, Zhang X, Han Q, Lv Y, Liu Z
Cancer Management and Research 2018, 10:941-951
Published Date: 1 May 2018

Durvalumab: a potential maintenance therapy in surgery-ineligible non-small-cell lung cancer
Shafique MR, Robinson LA, Antonia S
Cancer Management and Research 2018, 10:931-940
Published Date: 1 May 2018

Prognostic value of microRNAs in colorectal cancer: a meta-analysis
Gao S, Zhao ZY, Wu R, Zhang Y, Zhang ZY
Cancer Management and Research 2018, 10:907-929
Published Date: 30 April 2018

A favorable tumor size to define papillary thyroid microcarcinoma: an analysis of 1176 consecutive cases
Gong YP, Li GP, Lei JY, You JY, Jiang K, Li ZH, Gong RX, Zhu JQ
Cancer Management and Research 2018, 10:899-906
Published Date: 27 April 2018

Paeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation
Wang Z, Yu G, Liu Z, Zhu J, Chen C, Liu R, Xu R
Cancer Management and Research 2018, 10:887-897
Published Date: 27 April 2018

Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma
Yang LH, Wang Y, Qiao S, Wang MJ, Chen F, Zi XY, Li JX, Zhang HB, Yu B, Hu YP
Cancer Management and Research 2018, 10:873-885
Published Date: 26 April 2018

Association of two FOXP3 polymorphisms with breast cancer susceptibility in Chinese Han women
Tian T, Wang M, Zheng Y, Yang T, Zhu W, Li H, Lin S, Liu K, Xu P, Deng Y, Zhou L, Dai Z
Cancer Management and Research 2018, 10:867-872
Published Date: 26 April 2018

Elevated circulating miR-182 acts as a diagnostic biomarker for early colorectal cancer
Liu X, Xu T, Hu X, Chen X, Zeng K, Sun L, Wang S
Cancer Management and Research 2018, 10:857-865
Published Date: 24 April 2018

A novel nomogram for the prediction of intrahepatic cholangiocarcinoma in patients with intrahepatic lithiasis complicated by imagiologically diagnosed mass
Chen G, Yu H, Wang Y, Li C, Zhou M, Yu Z, Zheng X, Wu X, Shan Y, Zhang Q, Zeng Q
Cancer Management and Research 2018, 10:847-856
Published Date: 23 April 2018

Transoral robotic surgery for oropharyngeal cancer: patient selection and special considerations
Baskin RM, Boyce BJ, Amdur R, Mendenhall WM, Hitchcock K, Silver N, Dziegielewski PT
Cancer Management and Research 2018, 10:839-846
Published Date: 20 April 2018

Emergency treatment of complicated colorectal cancer
Tebala GD, Natili A, Gallucci A, Brachini G, Khan AQ, Tebala D, Mingoli A
Cancer Management and Research 2018, 10:827-838
Published Date: 20 April 2018

Prognostic significance of preoperative serum albumin in epithelial ovarian cancer patients: a systematic review and dose–response meta-analysis of observational studies
Ge LN, Wang F
Cancer Management and Research 2018, 10:815-825
Published Date: 17 April 2018

Effective prevention of sorafenib-induced hand–foot syndrome by dried-bonito broth
Kamimura K, Shinagawa-Kobayashi Y, Goto R, Ogawa K, Yokoo T, Sakamaki A, Abe S, Kamimura H, Suda T, Baba H, Tanaka T, Nozawa Y, Koyama N, Takamura M, Kawai H, Yamagiwa S, Aoyagi Y, Terai S
Cancer Management and Research 2018, 10:805-813
Published Date: 17 April 2018

Identification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinoma
Liao X, Zhu G, Huang R, Yang C, Wang X, Huang K, Yu T, Han C, Su H, Peng T
Cancer Management and Research 2018, 10:787-803
Published Date: 13 April 2018

MicroRNA-142-3p is involved in regulation of MGMT expression in glioblastoma cells
Lee YY, Yarmishyn AA, Wang ML, Chen HY, Chiou S, Yang YP, Lin C, Huang PI, Chen YW, Ma HI, Chen M
Cancer Management and Research 2018, 10:775-785
Published Date: 12 April 2018

Genetic variants in the nucleotide excision repair pathway genes and gastric cancer susceptibility in a southern Chinese population
He J, Zhuo Z, Zhang A, Zhu J, Hua R, Xue W, Zhang S, Zhang J, Li X, Jia W
Cancer Management and Research 2018, 10:765-774
Published Date: 12 April 2018

Quantitative assessment of the clinical susceptibility of calcium-sensing receptor polymorphisms in cancer patients
Huang H, Li T, Liao D, Zhu Z, Dong Y
Cancer Management and Research 2018, 10:755-763
Published Date: 12 April 2018

The role of the pathology department in the preanalytical phase of molecular analyses

Susman S, Berindan-Neagoe I, Petrushev B, Pirlog R, Florian IS, Mihu CM, Berce C, Craciun L, Grewal R, Tomuleasa C
Cancer Management and Research 2018, 10:745-753
Published Date: 12 April 2018

Management of hemorrhage in gastrointestinal stromal tumors: a review

Liu Q, Kong F, Zhou J, Dong M, Dong Q
Cancer Management and Research 2018, 10:735-743
Published Date: 12 April 2018

Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation
Guo W, Tan HY, Wang N, Wang XB, Feng YB
Cancer Management and Research 2018, 10:715-734
Published Date: 11 April 2018

Robotic versus laparoscopic gastrectomy with D2 lymph node dissection for advanced gastric cancer: a propensity score-matched analysis
Li Z, Li J, Li B, Bai B, Liu Y, Lian B, Zhao Q
Cancer Management and Research 2018, 10:705-714
Published Date: 10 April 2018

The association of polymorphisms in miRNAs with nonsmall cell lung cancer in a Han Chinese population
Li C, Zhang Y, Li Y, Ma Q, Liu S, Yao Y, Tan F, Shi L, Yao Y
Cancer Management and Research 2018, 10:697-704
Published Date: 10 April 2018

Marker of proliferation Ki-67 expression is associated with transforming growth factor beta 1 and can predict the prognosis of patients with hepatic B virus-related hepatocellular carcinoma
Yang C, Su H, Liao X, Han C, Yu T, Zhu G, Wang X, Winkler CA, O'Brien SJ, Peng T
Cancer Management and Research 2018, 10:679-696
Published Date: 10 April 2018

The impact of the lymph node density on overall survival in patients with Wilms’ tumor: A SEER analysis
You H, Yang J, Liu Q, Tang L, Bu Q, Pan Z, Lyu J
Cancer Management and Research 2018, 10:671-677
Published Date: 6 April 2018

ANLN functions as a key candidate gene in cervical cancer as determined by integrated bioinformatic analysis
Xia L, Su X, Shen J, Meng Q, Yan J, Zhang C, Chen Y, Wang H, Xu M
Cancer Management and Research 2018, 10:663-670
Published Date: 5 April 2018

Poorer prognosis in young female patients with non-metastatic colorectal cancer: a hospital-based analysis of 5,047 patients in China
Shen L, Mo M, Jia L, Jia H, Li Q, Liang L, Shi D, Zhang Z, Cai S, Li X, Zhu J
Cancer Management and Research 2018, 10:653-661
Published Date: 4 April 2018

Spotlight on dabrafenib/trametinib in the treatment of non-small-cell lung cancer: place in therapy
Weart TC, Miller KD, Simone CB II
Cancer Management and Research 2018, 10:647-652
Published Date: 3 April 2018

The association between long-term conditions and uptake of population-based screening for colorectal cancer: results from two English cohort studies
Kearns B, Chilcott J, Relton C, Whyte S, Woods HB, Nickerson C, Loban A
Cancer Management and Research 2018, 10:637-645
Published Date: 28 March 2018

Prognostic significance of leukopenia during the induction phase in adult B cell acute lymphoblastic leukemia
Xing C, Liang B, Wu J, Yang Q, Hu G, Yan Y, Zhang Y, Jiang S, Yu K, Feng J
Cancer Management and Research 2018, 10:625-635
Published Date: 28 March 2018

Management of relapsed/refractory marginal zone lymphoma: focus on ibrutinib
Denlinger NM, Epperla N, William BM
Cancer Management and Research 2018, 10:615-624
Published Date: 27 March 2018

Economic burden of the management of metastatic castrate-resistant prostate cancer in Italy: a cost of illness study [Corrigendum]
Restelli U, Ceresoli GL, Croce D, Evangelista L, Maffioli LS, Gianoncelli L, Bombardieri E
Cancer Management and Research 2018, 10:613-614
Published Date: 27 March 2018

The mutation of hepatitis B virus and the prognosis of hepatocellular carcinoma after surgery: a pilot study
Zhang Y, Huang J, Chen J, Yang K, Chen J, Xu L, Zhou Z, Chen M
Cancer Management and Research 2018, 10:599-611
Published Date: 27 March 2018

SYK expression level distinguishes control from BRCA1-mutated lymphocytes
Zahavi T, Sonnenblick A, Shimshon Y, Kadouri L, Peretz T, Salmon AY, Salmon-Divon M
Cancer Management and Research 2018, 10:589-598
Published Date: 26 March 2018

Bimodality treatment of patients with pelvic adenoid cystic carcinoma with photon intensity-modulated radiotherapy plus carbon ion boost: a case series

Bernhardt D, Sterzing F, Adeberg S, Herfarth K, Katayama S, Foerster R, Hoerner-Rieber J, König L, Debus J, Rieken S
Cancer Management and Research 2018, 10:583-588
Published Date: 26 March 2018

L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway

Bai E, Yang L, Xiang Y, Hu W, Li C, Lin J, Dai X, Liang G, Jin R, Zhao C
Cancer Management and Research 2018, 10:565-581
Published Date: 23 March 2018

Management and prognosis of patients with liver metastases from gestational trophoblastic neoplasia: a retrospective cohort study
Zong LJ, Yang JJ, Wang XY, Kong YJ, Ren T, Zhao J, Feng FZ, Wan XR, Xiang Y
Cancer Management and Research 2018, 10:557-563
Published Date: 23 March 2018

Mechanical ventilation promotes lung metastasis in experimental 4T1 breast cancer lung-metastasized models
Huang YL, Pan L, Helou K, Xia QS, Parris TZ, Li HY, Xu B, Li H
Cancer Management and Research 2018, 10:545-555
Published Date: 20 March 2018

Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3
Zhou J, Zhang WW, Peng F, Sun JY, He ZY, Wu SG
Cancer Management and Research 2018, 10:535-544
Published Date: 19 March 2018

Prognostic value of ductal carcinoma in situ component in invasive ductal carcinoma of the breast: a Surveillance, Epidemiology, and End Results database analysis
Wu SG, Zhang WW, Sun JY, He ZY
Cancer Management and Research 2018, 10:527-534
Published Date: 19 March 2018

Prospective study of neoadjuvant chemoradiotherapy using intensity-modulated radiotherapy and 5 fluorouracil for locally advanced rectal cancer – toxicities and response assessment
Simson DK, Mitra S, Ahlawat P, Saxena U, Kumar Sharma M, Rawat S, Singh H, Bansal B, Sripathi LK, Tanwar A
Cancer Management and Research 2018, 10:519-526
Published Date: 19 March 2018


Primary clear cell carcinoma of the thymus and literature comparison of features


Dai X, Zhao L, Peng F
Cancer Management and Research 2018, 10:513-518
Published Date: 16 March 2018

Upregulation of Arp2 expression is associated with the prognosis and prediction of lymph node metastasis in bladder urothelial carcinoma
Xu N, Qu GY, Wu YP, Li XD, Lin MY, Chen SH, Xue XY, Wei Y
Cancer Management and Research 2018, 10:503-511
Published Date: 19 March 2018

Immunocompetence and mechanism of the DRibble-DCs vaccine for oral squamous cell carcinoma
Dong H, Su H, Chen L, Liu K, Hu HM, Yang WD, Mou YB
Cancer Management and Research 2018, 10:493-501
Published Date: 16 March 2018

Intensity of treatment in Swiss cancer patients at the end-of-life
Bähler C, Signorell A, Blozik E, Reich O
Cancer Management and Research 2018, 10:481-491
Published Date: 15 March 2018

Moderate hypofractionated radiotherapy after prostatectomy for cancer patients: toxicity and clinical outcome
Barra S, Belgioia L, Marcenaro M, Callegari S, Pastorino A, Trapani L, Cavagnetto F, Garelli S, Corvò R
Cancer Management and Research 2018, 10:473-480
Published Date: 12 March 2018

Clinical behaviors of rare variants of papillary thyroid carcinoma are associated with survival: a population-level analysis
Jiang CH, Cheng T, Zheng XC, Hong SK, Liu S, Liu JJ, Wang J, Wang SY
Cancer Management and Research 2018, 10:465-472
Published Date: 9 March 2018

Optimized multiparametric flow cytometric analysis of circulating endothelial cells and their subpopulations in peripheral blood of patients with solid tumors: a technical analysis
Zhou F, Zhou Y, Yang M, Wen J, Dong J, Tan W
Cancer Management and Research 2018, 10:447-464
Published Date: 8 March 2018

Adenosquamous carcinoma of the bile duct: a population-based study
Qin BD, Jiao XD, Yuan LY, Liu K, Zang YS
Cancer Management and Research 2018, 10:439-446
Published Date: 7 March 2018


Evolution of regorafenib from bench to bedside in colorectal cancer: Is it an attractive option or merely a “me too” drug?


Goel G
Cancer Management and Research 2018, 10:425-437
Published Date: 6 March 2018

A novel mechanism of tumor-induced thymic atrophy in mice bearing H22 hepatocellular carcinoma
Sun SJ, Ji HY, Feng YY, Kang Y, Yu J, Liu AJ
Cancer Management and Research 2018, 10:417-424
Published Date: 5 March 2018

Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?
Kulsoom B, Shamsi TS, Afsar NA, Memon Z, Ahmed N, Hasnain SN
Cancer Management and Research 2018, 10:403-416
Published Date: 2 March 2018

Coordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition
Liu J, Yu Z, Xiao Y, Meng Q, Wang Y, Chang W
Cancer Management and Research 2018, 10:391-402
Published Date: 1 March 2018

Quality of life of young Chinese breast cancer patients after adjuvant chemotherapy
Yeo W, Mo FKF, Pang E, Suen JJS, Koh J, Yip CHW, Yip CCH, Li L, Loong HHF, Liem GS
Cancer Management and Research 2018, 10:383-389
Published Date: 22 February 2018

High C-reactive protein/albumin ratio predicts unfavorable distant metastasis-free survival in nasopharyngeal carcinoma: a propensity score-matched analysis
Wang Y, Yang L, Xia LP, Chen Y
Cancer Management and Research 2018, 10:371-381
Published Date: 21 February 2018

Surgical resection improves long-term survival of patients with hepatocellular carcinoma across different Barcelona Clinic Liver Cancer stages
Guo H, Wu T, Lu Q, Li M, Guo JY, Shen Y, Wu Z, Nan KJ, Lv Y, Zhang XF
Cancer Management and Research 2018, 10:361-369
Published Date: 21 February 2018

Patients with osteosarcoma and soft tissue sarcoma might become "cancer refugees" in some Japanese regional cities
Yamane H, Kunisada T, Ozaki T, Ochi N, Honda Y, Nagasaki Y, Nakagawa N, Yamagishi T, Nakanishi H, Takigawa N
Cancer Management and Research 2018, 10:353-359
Published Date: 19 February 2018

MicroRNA–mRNA expression profiles associated with medulloblastoma subgroup 4
Gershanov S, Toledano H, Michowiz S, Barinfeld O, Pinhasov A, Goldenberg-Cohen N, Salmon-Divon M
Cancer Management and Research 2018, 10:339-352
Published Date: 16 February 2018

The role of calgranulin B gene on the biological behavior of squamous cervical cancer in vitro and in vivo
Zhang W, Chen M, Cheng H, Shen Q, Wang Y, Zhu X
Cancer Management and Research 2018, 10:323-338
Published Date: 16 February 2018

Combination of CRP and NLR: a better predictor of postoperative survival in patients with gastric cancer
Guo J, Chen S, Chen Y, Li S, Xu D
Cancer Management and Research 2018, 10:315-321
Published Date: 14 February 2018

The role of cytokines and chemokines in the microenvironment of the blood–brain barrier in leukemia central nervous system metastasis
Si M, Jiao X, Li Y, Chen H, He P, Jiang F
Cancer Management and Research 2018, 10:305-313
Published Date: 12 February 2018


Husbands’ perceptions of their wives’ breast cancer coping efficacy: testing congruence models of adjustment
Merluzzi TV, Martinez Sanchez M
Cancer Management and Research 2018, 10:297-304
Published Date: 12 February 2018

Bone metastasis pattern in initial metastatic breast cancer: a population-based study
Xiong Z, Deng G, Huang X, Li X, Xie X, Wang J, Shuang Z, Wang X
Cancer Management and Research 2018, 10:287-295
Published Date: 9 February 2018

Neoadjuvant chemotherapy among patients treated for nonmetastatic breast cancer in a population with a high HIV prevalence in Johannesburg, South Africa
Ruff P, Cubasch H, Joffe M, Rosenbaum E, Murugan N, Tsai MC, Ayeni O, Crew KD, Jacobson JS, Neugut AI
Cancer Management and Research 2018, 10:279-286
Published Date: 9 February 2018

Uncemented three-dimensional-printed prosthetic replacement for giant cell tumor of distal radius: a new design of prosthesis and surgical techniques

Lu MX, Min L, Xiao C, Li YJ, Luo Y, Zhou Y, Zhang WL, Tu CQ
Cancer Management and Research 2018, 10:265-277
Published Date: 8 February 2018

Anastomotic reinforcement with omentoplasty reduces anastomotic leakage for minimally invasive esophagectomy with cervical anastomosis

Zhou D, Liu QX, Deng XF, Zheng H, Lu X, Dai JG, Jiang L
Cancer Management and Research 2018, 10:257-263
Published Date: 7 February 2018

Comparative effectiveness of early-line nab-paclitaxel vs. paclitaxel in patients with metastatic breast cancer: a US community-based real-world analysis
Mahtani RL, Parisi M, Glück S, Ni Q, Park S, Pelletier C, Faria C, Braiteh F
Cancer Management and Research 2018, 10:249-256
Published Date: 8 February 2018

Gastric cancer: epidemiology, prevention, classification, and treatment
Sitarz R, Skierucha M, Mielko J, Offerhaus GJA, Maciejewski R, Polkowski WP
Cancer Management and Research 2018, 10:239-248
Published Date: 7 February 2018

Comparison of prognostic prediction between nomogram based on lymph node ratio and AJCC 8th staging system for patients with resected pancreatic head carcinoma: a SEER analysis
Pu N, Li JA, Xu YL, Lee WL, Fang Y, Han X, Zhao GC, Zhang L, Nuerxiati A, Yin HL, Wu WC, Lou WH
Cancer Management and Research 2018, 10:227-238
Published Date: 5 February 2018

Influential factors on radiotherapy efficacy and prognosis in patients with secondary lymph node metastasis after esophagectomy of thoracic esophageal squamous cell carcinoma
Zhou SB, Guo XW, Gu L, Ji SJ
Cancer Management and Research 2018, 10:217-225
Published Date: 2 February 2018

Advances in the treatment of soft tissue sarcoma: focus on eribulin
Koliou P, Karavasilis V, Theochari M, Pollack SM, Jones RL, Thway K
Cancer Management and Research 2018, 10:207-216
Published Date: 1 February 2018

Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
Han S, Gao J, Zhou Q, Liu S, Wen C, Yang X
Cancer Management and Research 2018, 10:199-206
Published Date: 31 January 2018

Early diagnostic potential of APC hypermethylation in esophageal cancer
Wang B, Song H, Jiang H, Fu Y, Ding X, Zhou C
Cancer Management and Research 2018, 10:181-198
Published Date: 1 February 2018

Adrenal myelolipoma with hyperandrogenemia and schizophrenia

Liu N, Zhang W, Tan J, Zhou J, Yu X, Ren N, Fang Z, Jiao W, Fan Y, Liu C
Cancer Management and Research 2018, 10:177-180
Published Date: 1 February 2018

Treatment and outcomes of non-small-cell lung cancer patients with high comorbidity
Rios J, Gosain R, Goulart BHL, Huang B, Oechsli MN, McDowell JK, Chen Q, Tucker T, Kloecker GH
Cancer Management and Research 2018, 10:167-175
Published Date: 24 January 2018

Solute carrier transporters: potential targets for digestive system neoplasms
Xie J, Zhu XY, Liu LM, Meng ZQ
Cancer Management and Research 2018, 10:153-166
Published Date: 24 January 2018

Association between body mass index and breast cancer risk: evidence based on a dose–response meta-analysis
Liu K, Zhang W, Dai Z, Wang M, Tian T, Liu X, Kang H, Guan H, Zhang S, Dai Z
Cancer Management and Research 2018, 10:143-151
Published Date: 18 January 2018

Radiation-induced secondary malignancies for nasopharyngeal carcinoma: a pilot study of patients treated via IMRT or VMAT
Lee HF, Lan JH, Chao PJ, Ting HM, Chen HC, Hsu HC, Lee TF
Cancer Management and Research 2018, 10:131-141
Published Date: 18 January 2018

The role of brigatinib in crizotinib-resistant non-small cell lung cancer
Mezquita L, Planchard D
Cancer Management and Research 2018, 10:123-130
Published Date: 18 January 2018

A comparison of QuantStudio™ 3D Digital PCR and ARMS-PCR for measuring plasma EGFR T790M mutations of NSCLC patients
Feng Q, Gai F, Sang Y, Zhang J, Wang P, Wang Y, Liu B, Lin D, Yu Y, Fang J
Cancer Management and Research 2018, 10:115-121
Published Date: 18 January 2018

The relationship between the PD-1/PD-L1 pathway and DNA mismatch repair in cervical cancer and its clinical significance
Feng YC, Ji WL, Yue N, Huang YC, Ma XM
Cancer Management and Research 2018, 10:105-113
Published Date: 18 January 2018

Neoadjuvant treatments in triple-negative breast cancer patients: where we are now and where we are going
Omarini C, Guaitoli G, Pipitone S, Moscetti L, Cortesi L, Cascinu S, Piacentini F
Cancer Management and Research 2018, 10:91-103
Published Date: 15 January 2018

The potential role of angiogenesis in the development of shoulder pain, shoulder dysfunction, and lymphedema after breast cancer treatment
Mafu TS, September AV, Shamley D
Cancer Management and Research 2018, 10:81-90
Published Date: 15 January 2018

Toxic elements as biomarkers for breast cancer: a meta-analysis study
Jouybari L, Saei Ghare Naz M, Sanagoo A, Kiani F, Sayehmiri F, Sayehmiri K, Hasanpour Dehkordi A
Cancer Management and Research 2018, 10:69-79
Published Date: 10 January 2018

Vulvar carcinoma: dilemma, debates, and decisions
Mitra S, Kumar Sharma M, Kaur I, Khurana R, Batra Modi K, Narang R, Mandal A, Dutta S
Cancer Management and Research 2018, 10:61-68
Published Date: 9 January 2018

Detection of circulating tumor cells in liquid biopsy from Ewing sarcoma patients
Benini S, Gamberi G, Cocchi S, Garbetta J, Alberti L, Righi A, Gambarotti M, Picci P, Ferrari S
Cancer Management and Research 2018, 10:49-60
Published Date: 9 January 2018

Young age increases risk for lymph node positivity but decreases risk for non-small cell lung cancer death
Xia W, Wang A, Jin M, Mao Q, Xia W, Dong G, Chen B, Ma W, Xu L, Jiang F
Cancer Management and Research 2018, 10:41-48
Published Date: 8 January 2018

The reciprocal relationship between coping mechanisms and lung cancer diagnosis: findings of a prospective study
Oancea C, Suciu C, Timar B, Papava I, Raica M, Burlacu O
Cancer Management and Research 2018, 10:33-40
Published Date: 4 January 2018

Effects of marital status on survival of hepatocellular carcinoma by race/ethnicity and gender
Wu W, Fang D, Shi D, Bian X, Li L
Cancer Management and Research 2018, 10:23-32
Published Date: 3 January 2018

Radiotherapy for esophageal carcinoma: dose, response and survival
Luo Y, Mao Q, Wang X, Yu J, Li M
Cancer Management and Research 2018, 10:13-21
Published Date: 29 December 2017

Programmed death-ligand 1 expression correlates with diminished CD8+ T cell infiltration and predicts poor prognosis in anal squamous cell carcinoma patients
Zhao Y, Sun WP, Peng J, Deng Y, Fang Y, Huang J, Zhang H, Wan D, Lin J, Pan Z
Cancer Management and Research 2018, 10:1-11
Published Date: 18 December 2017