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Journal of Inflammation Research


Archive: Volume 14, 2021

TRAP1 Shows Clinical Significance in the Early Diagnosis of Small Cell Lung Cancer

Li X, Li X, Chen S, Wu Y, Liu Y, Hu T, Huang J, Yu J, Pei Z, Zeng T, Tan L

Journal of Inflammation Research 2021, 14:2507-2514

Published Date: 14 June 2021

Longitudinal Antibody Dynamics Against Structural Proteins of SARS-CoV-2 in Three COVID-19 Patients Shows Concurrent Development of IgA, IgM, and IgG

Jamiruddin MR, Haq MA, Tomizawa K, Kobatake E, Mie M, Ahmed S, Khandker SS, Ali T, Jahan N, Oishee MJ, Khondoker MU, Sil BK, Haque M, Adnan N

Journal of Inflammation Research 2021, 14:2497-2506

Published Date: 14 June 2021

Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?

Nangole FW, Ouyang K, Anzala O, Ogengo J, Agak GW

Journal of Inflammation Research 2021, 14:2465-2470

Published Date: 10 June 2021

LncRNA NEAT1 Promote Inflammatory Responses in Coronary Slow Flow Through Regulating miR-148b-3p/ICAM-1 Axis

Zhu Q, Zhao C, Wang Y, Li X, Xue Y, Ma C

Journal of Inflammation Research 2021, 14:2445-2463

Published Date: 9 June 2021

Occupational Cement Dust Exposure and Inflammatory Nemesis: Bangladesh Relevance

Ahmad R, Akhter QS, Haque M

Journal of Inflammation Research 2021, 14:2425-2444

Published Date: 9 June 2021

Protective Role of microRNA-200a in Diabetic Retinopathy Through Downregulation of PDLIM1

Wan W, Long Y, Jin X, Li Q, Wan W, Liu H, Zhu Y

Journal of Inflammation Research 2021, 14:2411-2424

Published Date: 4 June 2021

The Correlation Between Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio with Hepatic Echinococcosis

E Weijian, Wang Z, Pang MQ, Lu Y, Fan H

Journal of Inflammation Research 2021, 14:2403-2409

Published Date: 3 June 2021

Zc3h12d, a Novel of Hypomethylated and Immune-Related for Prognostic Marker of Lung Adenocarcinoma

Yang B, Ji LL, Xu HL, Li XP, Zhou HG, Xiao T, Li XH, Gao ZY, Li JZ, Zhang WD, Wang GS, Li MJ

Journal of Inflammation Research 2021, 14:2389-2401

Published Date: 15 June 2021

Multi-Organ Transcriptome Dynamics in a Mouse Model of Cecal Ligation and Puncture-Induced Polymicrobial Sepsis

Rumienczyk I, Kulecka M, Ostrowski J, Mar D, Bomsztyk K, Standage SW, Mikula M

Journal of Inflammation Research 2021, 14:2377-2388

Published Date: 3 June 2021

A Novel NGF Receptor Agonist B355252 Ameliorates Neuronal Loss and Inflammatory Responses in a Rat Model of Cerebral Ischemia

Wang HK, Chen JS, Hsu CY, Su YT, Sung TC, Liang CL, Kwan AL, Wu CC

Journal of Inflammation Research 2021, 14:2363-2376

Published Date: 1 June 2021

Identification of an Alveolar Macrophage-Related Core Gene Set in Acute Respiratory Distress Syndrome

Zhao C, Mo J, Zheng X, Wu Z, Li Q, Feng J, Luo J, Lu J, Zhang J

Journal of Inflammation Research 2021, 14:2353-2361

Published Date: 1 June 2021

Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice

Huang C, Cai J, Jin S, Lin Q, Fang Q, Nan K, Han Y, Ge W, Liu Y, Tao Y, Cao H, Li J

Journal of Inflammation Research 2021, 14:2301-2315

Published Date: 31 May 2021

Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation

Li N, Xiong R, He R, Liu B, Wang B, Geng Q

Journal of Inflammation Research 2021, 14:2289-2300

Published Date: 31 May 2021

Obesity-Related Inflammation and Endothelial Dysfunction in COVID-19: Impact on Disease Severity

De Lorenzo A, Estato V, Castro-Faria-Neto HC, Tibirica E

Journal of Inflammation Research 2021, 14:2267-2276

Published Date: 27 May 2021

Melatonin Inhibits Migration and Invasion in LPS-Stimulated and -Unstimulated Prostate Cancer Cells Through Blocking Multiple EMT-Relative Pathways

Tian QX, Zhang ZH, Ye QL, Xu S, Hong Q, Xing WY, Chen L, Yu DX, Xu DX, Xie DD

Journal of Inflammation Research 2021, 14:2253-2265

Published Date: 25 May 2021

Downregulation of Renal MRPs Transporters in Acute Lymphoblastic Leukemia Mediated by the IL-6/STAT3/PXR Signaling Pathway

Zhou Y, Nie AQ, Chen S, Wang MM, Yin R, Tang BH, Wu YE, Yang F, Du B, Shi HY, Yang XM, Hao GX, Guo XL, Han QJ, Zheng Y, Zhao W

Journal of Inflammation Research 2021, 14:2239-2252

Published Date: 25 May 2021

Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo

Chen Y, Chen Y, Jiang X, Shi M, Yang Z, Chen Z, Hua X, Chen J, Wang Y

Journal of Inflammation Research 2021, 14:2207-2223

Published Date: 25 May 2021

Role of Pyroptosis in Diabetes and Its Therapeutic Implications

Al Mamun A, Wu Y, Nasrin F, Akter A, Taniya MA, Munir F, Jia C, Xiao J

Journal of Inflammation Research 2021, 14:2187-2206

Published Date: 24 May 2021

Syk-Targeted, a New 3-Arylbenzofuran Derivative EAPP-2 Blocks Airway Inflammation of Asthma–COPD Overlap in vivo and in vitro

Li S, Hui Y, Yuan J, Zhang Z, Li X, Fang N, Lin M, Hou Q

Journal of Inflammation Research 2021, 14:2173-2185

Published Date: 24 May 2021

A Gender-Dependent Molecular Switch of Inflammation via MyD88/Estrogen Receptor-Alpha Interaction

El Sabeh R, Bonnet M, Le Corf K, Lang K, Kfoury A, Badran B, Hussein N, Virard F, Treilleux I, Le Romancer M, Lebecque S, Manie S, Coste I, Renno T

Journal of Inflammation Research 2021, 14:2149-2156

Published Date: 21 May 2021

Preclinical Characterization of the Selective JAK1 Inhibitor LW402 for Treatment of Rheumatoid Arthritis

Zhang N, Zhang C, Zeng Z, Zhang J, Du S, Bao C, Wang Z

Journal of Inflammation Research 2021, 14:2133-2147

Published Date: 21 May 2021

In vivo and in vitro Evaluation of Cytokine Expression Profiles During Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection

Mubarak A, Alrfaei B, Aljurayyan A, Alqafil MM, Farrag MA, Hamed ME, Alosaimi B, Almajhdi F, Alturaiki W

Journal of Inflammation Research 2021, 14:2121-2131

Published Date: 21 May 2021

A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies

Kulke M, Nagel F, Schulig L, Geist N, Gabor M, Mayerle J, Lerch MM, Link A, Delcea M

Journal of Inflammation Research 2021, 14:2111-2119

Published Date: 21 May 2021

Fat-Soluble Vitamins and the Current Global Pandemic of COVID-19: Evidence-Based Efficacy from Literature Review

Samad N, Dutta S, Sodunke TE, Fairuz A, Sapkota A, Miftah ZF, Jahan I, Sharma P, Abubakar AR, Rowaiye AB, Oli AN, Charan J, Islam S, Haque M

Journal of Inflammation Research 2021, 14:2091-2110

Published Date: 21 May 2021

Role of Ferroptosis in Lung Diseases

Xu W, Deng H, Hu S, Zhang Y, Zheng L, Liu M, Chen Y, Wei J, Yang H, Lv X

Journal of Inflammation Research 2021, 14:2079-2090

Published Date: 20 May 2021

The ACE2-Ang-(1‑7)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Mediated NF-кb and MAPK Pathways

Pan H, Huang W, Wang Z, Ren F, Luo L, Zhou J, Tian M, Tang L

Journal of Inflammation Research 2021, 14:2045-2060

Published Date: 20 May 2021

Association Between Interleukin-12 and Sarcopenia

Chen YY, Kao TW, Chiu YL, Peng TC, Yang HF, Chen WL

Journal of Inflammation Research 2021, 14:2019-2029

Published Date: 18 May 2021

Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways

Ye W, Yan Y, Tang Y, Dong X, Chen G, Kang J, Huang L, Xiong Q, Feng Z

Journal of Inflammation Research 2021, 14:2007-2017

Published Date: 18 May 2021

Prognostic Significance of Tumor-Associated Macrophages in Chondroblastoma and Their Association with Response to Adjuvant Radiotherapy

Zheng BW, Yang ML, Huang W, Zheng BY, Zhang TL, Li J, Lv GH, Yan YG, Zou MX

Journal of Inflammation Research 2021, 14:1991-2005

Published Date: 17 May 2021

Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages

Wang R, Song W, Xie C, Zhong W, Xu H, Zhou Q, Deng Y, Hong Y, Li X, Fang M

Journal of Inflammation Research 2021, 14:1973-1989

Published Date: 17 May 2021

Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice

Li L, Yang L, Yang F, Zhao XL, Xue SJ, Gong FH

Journal of Inflammation Research 2021, 14:1959-1971

Published Date: 17 May 2021

Effect of Biologics on Cardiovascular Inflammation: Mechanistic Insights and Risk Reduction

Fragoulis GE, Soulaidopoulos S, Sfikakis PP, Dimitroulas T, Kitas GD

Journal of Inflammation Research 2021, 14:1915-1931

Published Date: 14 May 2021

Punicalagin Inhibited Inflammation and Migration of Fibroblast-Like Synoviocytes Through NF-κB Pathway in the Experimental Study of Rheumatoid Arthritis

Huang M, Wu K, Zeng S, Liu W, Cui T, Chen Z, Lin L, Chen D, Ouyang H

Journal of Inflammation Research 2021, 14:1901-1913

Published Date: 12 May 2021

Risk of Non-Alcoholic Fatty Liver Disease in Xanthelasma Palpebrarum

Chen HW, Lin JC, Wu YH, Chiu YL

Journal of Inflammation Research 2021, 14:1891-1899

Published Date: 12 May 2021

The 4G/5G Polymorphism of Plasminogen Activator Inhibitor Type 1 is a Predictor of Moderate-to-Severe Thyroid Eye Disease

Katko M, Galgoczi E, Erdei A, Gazdag A, Berta E, Bodor M, Seres I, Hircsu I, Badics A, Ujhelyi B, Sira L, Bhattoa HP, Nagy EV

Journal of Inflammation Research 2021, 14:1883-1890

Published Date: 12 May 2021

MCTR1 Intervention Reverses Experimental Lung Fibrosis in Mice

Pan J, Li X, Wang X, Yang L, Chen H, Su N, Wu C, Hao Y, Jin S, Li H

Journal of Inflammation Research 2021, 14:1873-1881

Published Date: 11 May 2021

microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3

Yang QB, Li LQ, Zhang QB, He YL, Mi QS, Zhou JG

Journal of Inflammation Research 2021, 14:1845-1858

Published Date: 11 May 2021

Dual Activity of Ginsenoside Rb1 in Hypertrophic Cardiomyocytes and Activated Macrophages: Implications for the Therapeutic Intervention of Cardiac Hypertrophy

Wang S, Cui Y, Xiong M, Li M, Wang P, Cui J, Du X, Chen Y, Zhang T

Journal of Inflammation Research 2021, 14:1789-1806

Published Date: 5 May 2021

Activation of GSK3 Prevents Termination of TNF-Induced Signaling

Welz B, Bikker R, Hoffmeister L, Diekmann M, Christmann M, Brand K, Huber R

Journal of Inflammation Research 2021, 14:1717-1730

Published Date: 6 May 2021

Factors Associated with the Expression of ACE2 in Human Lung Tissue: Pathological Evidence from Patients with Normal FEV1 and FEV1/FVC

Bao W, Zhang X, Jin Y, Hao H, Yang F, Yin D, Chen X, Xue Y, Han L, Zhang M

Journal of Inflammation Research 2021, 14:1677-1687

Published Date: 28 April 2021

Ddb1-Cullin4-Associated-Factor 1 in Macrophages Restricts the Staphylococcus aureus-Induced Osteomyelitis

Zong Y, Shan H, Yin F, Ma X, Jiang C, Wang N, Zhou L, Lin Y, Zhou Z, Yu X

Journal of Inflammation Research 2021, 14:1667-1676

Published Date: 28 April 2021

Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways

Jin F, Geng F, Xu D, Li Y, Li T, Yang X, Liu S, Zhang H, Wei Z, Li S, Gao X, Cai W, Mao N, Yi X, Liu H, Sun Y, Yang F, Xu H

Journal of Inflammation Research 2021, 14:1647-1660

Published Date: 27 April 2021

An Indole-2-Carboxamide Derivative, LG4, Alleviates Diabetic Kidney Disease Through Inhibiting MAPK-Mediated Inflammatory Responses

Qian J, Yin S, Ye L, Wang Z, Shu S, Mou Z, Xu M, Chattipakorn N, Liu Z, Liang G

Journal of Inflammation Research 2021, 14:1633-1645

Published Date: 27 April 2021

Comprehensive Identification of Bridge Genes to Explain the Progression from Chronic Hepatitis B Virus Infection to Hepatocellular Carcinoma

Nong W, Ma L, Lan B, Liu N, Yang H, Lao X, Deng Q, Huang Z

Journal of Inflammation Research 2021, 14:1613-1624

Published Date: 21 April 2021

Inflammasome as an Effective Platform for Fibrosis Therapy

Chen TT, Xiao F, Li N, Shan S, Qi M, Wang ZY, Zhang SN, Wei W, Sun WY

Journal of Inflammation Research 2021, 14:1575-1590

Published Date: 20 April 2021

Silenced SNHG1 Inhibited Epithelial-Mesenchymal Transition and Inflammatory Response of ARPE-19 Cells Induced by High Glucose

Yang J, Yang K, Meng X, Liu P, Fu Y, Wang Y

Journal of Inflammation Research 2021, 14:1563-1573

Published Date: 20 April 2021

HMGB1/TLR4 Signaling Affects Regulatory T Cells in Acute Lung Injury

Zhou M, Zhang Y, Tang R, Liu H, Du M, Gao Z, Ji Z, Fang H

Journal of Inflammation Research 2021, 14:1551-1561

Published Date: 19 April 2021

Rosuvastatin Enhances Alveolar Fluid Clearance in Lipopolysaccharide-Induced Acute Lung Injury by Activating the Expression of Sodium Channel and Na,K-ATPase via the PI3K/AKT/Nedd4-2 Pathway

Xu HR, Yang Q, Xiang SY, Zhang PH, Ye Y, Chen Y, Xu KW, Ren XY, Mei HX, Shen CX, Ma HY, Smith FG, Jin SW, Wang Q

Journal of Inflammation Research 2021, 14:1537-1549

Published Date: 16 April 2021

Methanolic Fenugreek Seed Extract Induces p53-Dependent Mitotic Catastrophe in Breast Cancer Cells, Leading to Apoptosis

Alrumaihi FA, Khan MA, Allemailem KS, Alsahli MA, Almatroudi A, Younus H, Alsuhaibani SA, Algahtani M, Khan A

Journal of Inflammation Research 2021, 14:1511-1535

Published Date: 16 April 2021

Attenuating the Effects of Novel COVID-19 (SARS-CoV-2) Infection-Induced Cytokine Storm and the Implications

Rowaiye AB, Okpalefe OA, Onuh Adejoke O, Ogidigo JO, Hannah Oladipo O, Ogu AC, Oli AN, Olofinase S, Onyekwere O, Rabiu Abubakar A, Jahan D, Islam S, Dutta S, Haque M

Journal of Inflammation Research 2021, 14:1487-1510

Published Date: 16 April 2021

Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure

Wang Y, Li X, Chen Q, Jiao F, Shi C, Pei M, Wang L, Gong Z

Journal of Inflammation Research 2021, 14:1473-1485

Published Date: 15 April 2021

Study of the Expression of Inflammatory Factors IL-4, IL-6, IL-10, and IL-17 in Liver Failure Complicated by Coagulation Dysfunction and Sepsis

Li L, Chen L, Lin F, Mu J, Wang D, Zhang W, Mi L, Qin Y, Zhou Y

Journal of Inflammation Research 2021, 14:1447-1453

Published Date: 15 April 2021

Diet-Related Inflammation is Associated with Major Depressive Disorder in Bahraini Adults: Results of a Case-Control Study Using the Dietary Inflammatory Index

Chen W, Faris AIE, Bragazzi NL, AlGahtani HMS, Saif Z, Jahrami A, Shivappa N, Hebert JR, Jahrami H

Journal of Inflammation Research 2021, 14:1437-1445

Published Date: 15 April 2021

Acute Phase Responses Vary Between Children of HbAS and HbAA Genotypes During Plasmodium falciparum Infection

Tetteh M, Addai-Mensah O, Siedu Z, Kyei-Baafour E, Lamptey H, Williams J, Kupeh E, Egbi G, Kwayie AB, Abbam G, Afrifah DA, Debrah AY, Ofori MF

Journal of Inflammation Research 2021, 14:1415-1426

Published Date: 14 April 2021

Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study

Hu X, Li R, Sun M, Kong Y, Zhu H, Wang F, Wan Q

Journal of Inflammation Research 2021, 14:1403-1414

Published Date: 13 April 2021

Hydrogen (H2) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway

Lu H, Wang W, Kang X, Lin Z, Pan J, Cheng S, Zhang J

Journal of Inflammation Research 2021, 14:1387-1402

Published Date: 13 April 2021

LXA4 Inhibits Lipopolysaccharide-Induced Inflammatory Cell Accumulation by Resident Macrophages in Mice

Mei HX, Ye Y, Xu HR, Xiang SY, Yang Q, Ma HY, Jin SW, Wang Q

Journal of Inflammation Research 2021, 14:1375-1385

Published Date: 12 April 2021

Changes in Plasma Growth Differentiation Factor-15 After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients: A Prospective Study

Salman A, Shaaban HED, Salman M, M Seif El Nasr S, Soliman A, Salem A, Tag El-Din M, Mikhail HMS, El Domiaty H, Abd Allah N, GabAllah GMK, Youssef A

Journal of Inflammation Research 2021, 14:1365-1373

Published Date: 12 April 2021

Decreased T Cell Levels in Critically Ill Coronavirus Patients: Single-Center, Prospective and Observational Study

Xu J, Liu Z, Liu H, Luo Y, Kang K, Li X, Yang W, Fei D, Wang C, Yu K

Journal of Inflammation Research 2021, 14:1331-1340

Published Date: 9 April 2021

Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway

Naeem K, Tariq Al Kury L, Nasar F, Alattar A, Alshaman R, Shah FA, Khan AU, Li S

Journal of Inflammation Research 2021, 14:1313-1329

Published Date: 8 April 2021

SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury

Wang D, Cao H, Wang X, Wang J, Wang M, Zhang J, Wang L

Journal of Inflammation Research 2021, 14:1283-1296

Published Date: 7 April 2021

Interferon-λ3 Exacerbates the Inflammatory Response to Microbial Ligands: Implications for SARS-CoV-2 Pathogenesis

Read SA, Gloss BS, Liddle C, George J, Ahlenstiel G

Journal of Inflammation Research 2021, 14:1257-1270

Published Date: 1 April 2021

Tripterygium wilfordii Polyglycoside Ameliorated TNBS-Induced Colitis in Rats via Regulating Th17/Treg Balance in Intestinal Mucosa

Zhang C, Ju J, Wu X, Yang J, Yang Q, Liu C, Chen L, Sun X

Journal of Inflammation Research 2021, 14:1243-1255

Published Date: 1 April 2021

Dexmedetomidine Attenuates Ischemia/Reperfusion-Induced Myocardial Inflammation and Apoptosis Through Inhibiting Endoplasmic Reticulum Stress Signaling

Yang Y, Wang H, Song N, Jiang Y, Zhang J, Meng X, Feng X, Liu H, Peng K, Ji F

Journal of Inflammation Research 2021, 14:1217-1233

Published Date: 31 March 2021

Association of Early Inflammation with Age and Asymptomatic Disease in COVID-19

Xie C, Li Q, Li L, Peng X, Ling Z, Xiao B, Feng J, Chen Z, Chang D, Xie L, Dela Cruz CS, Sharma L

Journal of Inflammation Research 2021, 14:1207-1216

Published Date: 30 March 2021

Anti-Inflammatory and Antiviral Osmotic Polymeric Film to Treat Covid-19 Early-Stage Infection

Shrivastava R, Shrivastava R, Johansen B, Allain T

Journal of Inflammation Research 2021, 14:1195-1206

Published Date: 30 March 2021

Anti-TWEAK Antibody Alleviates Renal Interstitial Fibrosis by Increasing PGC-1α Expression in Lupus Nephritis

Xue L, Zhang Y, Xu J, Lu W, Wang Q, Fu J, Liu Z

Journal of Inflammation Research 2021, 14:1173-1184

Published Date: 26 March 2021

Helping Roles of Artificial Intelligence (AI) in the Screening and Evaluation of COVID-19 Based on the CT Images

Xie H, Li Q, Hu PF, Zhu SH, Zhang JF, Zhou HD, Zhou HB

Journal of Inflammation Research 2021, 14:1165-1172

Published Date: 26 March 2021

Activation and Inhibition of the NLRP3 Inflammasome by RNA Viruses

Choudhury SM, Ma X, Abdullah SW, Zheng H

Journal of Inflammation Research 2021, 14:1145-1163

Published Date: 26 March 2021

Restraint Stress in Hypertensive Rats Activates the Intestinal Macrophages and Reduces Intestinal Barrier Accompanied by Intestinal Flora Dysbiosis

Wang T, Gao L, Yang Z, Wang F, Guo Y, Wang B, Hua R, Shang H, Xu J

Journal of Inflammation Research 2021, 14:1085-1110

Published Date: 25 March 2021

FUT7 Promotes the Epithelial–Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma

Liu M, Zheng Q, Chen S, Liu J, Li S

Journal of Inflammation Research 2021, 14:1069-1084

Published Date: 25 March 2021

Complement Profiles in Patients with Amyotrophic Lateral Sclerosis: A Prospective Observational Cohort Study

Kjældgaard AL, Pilely K, Olsen KS, Øberg Lauritsen A, Wørlich Pedersen S, Svenstrup K, Karlsborg M, Thagesen H, Blaabjerg M, Theódórsdóttir Á, Gundtoft Elmo E, Torvin Møller A, Pedersen NA, Kirkegaard N, Møller K, Garred P

Journal of Inflammation Research 2021, 14:1043-1053

Published Date: 23 March 2021

Metalloproteinases in Inflammatory Bowel Diseases

Marônek M, Marafini I, Gardlík R, Link R, Troncone E, Monteleone G

Journal of Inflammation Research 2021, 14:1029-1041

Published Date: 23 March 2021

BT2 Suppresses Human Monocytic-Endothelial Cell Adhesion, Bone Erosion and Inflammation

Yeh MC, Wu BJ, Li Y, Elahy M, Prado-Lourenco L, Sockler J, Lau H, Day RO, Khachigian LM

Journal of Inflammation Research 2021, 14:1019-1028

Published Date: 23 March 2021

The Influence of an Occult Infection on the Outcome of Autologous Bone Grafting During Surgical Bone Reconstruction: A Large Single-Center Case-Control Study

Tanner MC, Heller RA, Grimm A, Zimmermann S, Pilz M, Jurytko L, Miska M, Helbig L, Schmidmaier G, Haubruck P

Journal of Inflammation Research 2021, 14:995-1005

Published Date: 22 March 2021

Poor Clearance of Free Hemoglobin Due to Lower Active Haptoglobin Availability is Associated with Osteoarthritis Inflammation

Sarkar A, Monu, Kumar V, Malhotra R, Pandit H, Jones E, Ponchel F, Biswas S

Journal of Inflammation Research 2021, 14:949-964

Published Date: 18 March 2021

The Binary Classification of Protein Kinases

Elkoshi Z

Journal of Inflammation Research 2021, 14:929-947

Published Date: 18 March 2021

Altered Monocyte Subsets in Kawasaki Disease Revealed by Single-cell RNA-Sequencing

Geng Z, Tao Y, Zheng F, Wu L, Wang Y, Wang Y, Sun Y, Fu S, Wang W, Xie C, Zhang Y, Gong F

Journal of Inflammation Research 2021, 14:885-896

Published Date: 16 March 2021

Estrogen Protects Articular Cartilage by Downregulating ASIC1a in Rheumatoid Arthritis

Hang X, Zhang Z, Niu R, Wang C, Yao J, Xu Y, Tao J, Li L, Chen F

Journal of Inflammation Research 2021, 14:843-858

Published Date: 12 March 2021

Screening of Key Genes of Sepsis and Septic Shock Using Bioinformatics Analysis

Zeng X, Feng J, Yang Y, Zhao R, Yu Q, Qin H, Wei L, Ji P, Li H, Wu Z, Zhang J

Journal of Inflammation Research 2021, 14:829-841

Published Date: 11 March 2021

Sodium Propionate Enhances Nrf2-Mediated Protective Defense Against Oxidative Stress and Inflammation in Lipopolysaccharide-Induced Neonatal Mice

Chen D, Gao Z, Wang Y, Wan B, Liu G, Chen J, Wu Y, Zhou Q, Jiang S, Yu R, Pang Q

Journal of Inflammation Research 2021, 14:803-816

Published Date: 10 March 2021

Integrated Bioinformatic Analysis of SARS-CoV-2 Infection Related Genes ACE2, BSG and TMPRSS2 in Aerodigestive Cancers

He C, Hua X, Sun S, Li S, Wang J, Huang X

Journal of Inflammation Research 2021, 14:791-802

Published Date: 10 March 2021

Endothelin-1/Endothelin Receptor Type A-Angiopoietins/Tie-2 Pathway in Regulating the Cross Talk Between Glomerular Endothelial Cells and Podocytes in Trichloroethylene-Induced Renal Immune Injury

Xie H, Wang H, Wu Q, Peng J, Huang H, Wang Y, Huang M, Jiang W, Yang Y, Zhang X, Zhang J, Zhu Q

Journal of Inflammation Research 2021, 14:761-776

Published Date: 9 March 2021

Possible Role of Regulatory B Cells in Different Behçet’s Disease Phenotypes and Therapies: First Report from Egypt

Hetta HF, Mohamed AAA, Zahran AM, Mahran SA, Sayed MM, Saleh MGA, Abdelazeem K, Batiha GES, Al-Rejaie S, Waheed Y, Muhammad K, Hassanien MM

Journal of Inflammation Research 2021, 14:737-744

Published Date: 8 March 2021

KCa3.1 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease

Zheng F, Tao Y, Liu J, Geng Z, Wang Y, Wang Y, Fu S, Wang W, Xie C, Zhang Y, Gong F

Journal of Inflammation Research 2021, 14:719-735

Published Date: 5 March 2021

Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway

Shen R, Yin P, Yao H, Chen L, Chang X, Li H, Hou X

Journal of Inflammation Research 2021, 14:711-718

Published Date: 5 March 2021

Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats

Sucedaram Y, Johns EJ, Husain R, Abdul Sattar M, H Abdulla M, Nelli G, Rahim NS, Khalilpourfarshbafi M, Abdullah NA

Journal of Inflammation Research 2021, 14:689-710

Published Date: 5 March 2021

Susceptibility-Related Cytokine Panel for Prediction of Polygonum multiflorum-Induced Hepatotoxicity in Humans

Tu C, Niu M, Wei AW, Tang JF, Zhang L, Jing J, Xiao XH, Wang JB

Journal of Inflammation Research 2021, 14:645-655

Published Date: 4 March 2021

C-Reactive Protein Mediates the Effect of Serum Progesterone on Obesity for Men and Postmenopausal Women in Henan Rural Cohort Study

Nie L, Wei D, Liu P, Zhang L, Fan K, Song Y, Wang M, Wang L, Xu Q, Wang J, Liu X, Li L, Mao Z, Huang H, Wang C, Huo W

Journal of Inflammation Research 2021, 14:633-644

Published Date: 4 March 2021

Identification of Potential Early Diagnostic Biomarkers of Sepsis

Li Z, Huang B, Yi W, Wang F, Wei S, Yan H, Qin P, Zou D, Wei R, Chen N

Journal of Inflammation Research 2021, 14:621-631

Published Date: 3 March 2021

High Concentrations of Etanercept Reduce Human Islet Function and Integrity

Brandhorst D, Brandhorst H, Acreman S, Abraham A, Johnson PRV

Journal of Inflammation Research 2021, 14:599-610

Published Date: 26 February 2021

Markers of Chronic Inflammation in Overweight and Obese Individuals and the Role of Gender: A Cross-Sectional Study of a Large Cohort

Cohen E, Margalit I, Shochat T, Goldberg E, Krause I

Journal of Inflammation Research 2021, 14:567-573

Published Date: 25 February 2021

The Implications of Zinc Therapy in Combating the COVID-19 Global Pandemic

Samad N, Sodunke TE, Abubakar AR, Jahan I, Sharma P, Islam S, Dutta S, Haque M

Journal of Inflammation Research 2021, 14:527-550

Published Date: 26 February 2021

AST-120 Improves Cardiac Dysfunction in Acute Kidney Injury Mice via Suppression of Apoptosis and Proinflammatory NF-κB/ICAM-1 Signaling

Shen WC, Chou YH, Shi LS, Chen ZW, Tu HJ, Lin XY, Wang GJ

Journal of Inflammation Research 2021, 14:505-518

Published Date: 24 February 2021

Potential Biomarkers for Diagnosing Major Depressive Disorder Patients with Suicidal Ideation

Bai S, Fang L, Xie J, Bai H, Wang W, Chen J

Journal of Inflammation Research 2021, 14:495-503

Published Date: 22 February 2021

Regulation of Pancreatic Fibrosis by Acinar Cell-Derived Exosomal miR-130a-3p via Targeting of Stellate Cell PPAR-γ

Wang Q, Wang H, Jing Q, Yang Y, Xue D, Hao C, Zhang W

Journal of Inflammation Research 2021, 14:461-477

Published Date: 24 February 2021

Therapeutic Potentials of Colocasia affinis Leaf Extract for the Alleviation of Streptozotocin-Induced Diabetes and Diabetic Complications: In vivo and in silico-Based Studies

Shill MC, Bepari AK, Khan M, Tasneem Z, Ahmed T, Hasan MA, Alam MJ, Hossain M, Rahman MA, Sharker SM, Shahriar M, Rahman GMS, Reza HM

Journal of Inflammation Research 2021, 14:443-459

Published Date: 19 February 2021

Distinctive Under-Expression Profile of Inflammatory and Redox Genes in the Blood of Elderly Patients with Cardiovascular Disease

Milanesi E, Manda G, Dobre M, Codrici E, Neagoe IV, Popescu BO, Bajenaru OA, Spiru L, Tudose C, Prada GI, Davidescu EI, Piñol-Ripoll G, Cuadrado A

Journal of Inflammation Research 2021, 14:429-442

Published Date: 18 February 2021

Comprehensive Analysis of LncRNA-mRNA Expression Profiles and the ceRNA Network Associated with Pyroptosis in LPS-Induced Acute Lung Injury

Luo D, Liu F, Zhang J, Shao Q, Tao W, Xiao R, Dai W, Ding C, Qian K

Journal of Inflammation Research 2021, 14:413-428

Published Date: 17 February 2021

Securidaca inappendiculata-Derived Xanthones Protected Joints from Degradation in Male Rats with Collagen-Induced Arthritis by Regulating PPAR-γ Signaling

Zuo J, Tao MQ, Wu XY, Jiang TT, Olatunji OJ, Dong J, Han J, Ji CL

Journal of Inflammation Research 2021, 14:395-411

Published Date: 16 February 2021

Adenosine A2A Receptor Agonist Polydeoxyribonucleotide Alleviates Interstitial Cystitis-Induced Voiding Dysfunction by Suppressing Inflammation and Apoptosis in Rats

Ko IG, Jin JJ, Hwang L, Kim SH, Kim CJ, Won KY, Na YG, Kim KH, Kim SJ

Journal of Inflammation Research 2021, 14:367-378

Published Date: 15 February 2021

Exposure to Maternal Immune Activation Causes Congenital Unfolded Protein Response Defects and Increases the Susceptibility to Postnatal Inflammatory Stimulation in Offspring

Shimizu Y, Tsukada T, Sakata-Haga H, Sakai D, Shoji H, Saikawa Y, Hatta T

Journal of Inflammation Research 2021, 14:355-365

Published Date: 12 February 2021

Association of a High Neutrophil-to-Lymphocyte Ratio with Hyperdense Artery Sign and Unfavorable Short-Term Outcomes in Patients with Acute Ischemic Stroke

Lin SK, Chen PY, Chen GC, Hsu PJ, Hsiao CL, Yang FY, Liu CY, Tsou A

Journal of Inflammation Research 2021, 14:313-324

Published Date: 5 February 2021

Aryl Hydrocarbon Receptor is Essential in the Control of Lung Club Cell Homeostasis

Liu KY, Wang LT, Wang HC, Wang SN, Tseng LW, Chai CY, Chiou SS, Huang SK, Hsu SH

Journal of Inflammation Research 2021, 14:299-311

Published Date: 5 February 2021

Analysis of the Effect of Proton-Pump Inhibitors on the Course of COVID-19

Zhang XY, Li T, Wu H, Ling Y, Qian ZP, Chen L

Journal of Inflammation Research 2021, 14:287-298

Published Date: 5 February 2021

Association of Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study [Corrigendum]

Yousef AA, Mohamed FY, Boraey NF, Akeel NE, Soliman AA, Waked NM, Hashem MIA, Shehata H, Fahmy DS, Ismael A, Ibrahim LM, Ibrahim MAM, Salem HF, Yousry SM, Osman SF, Fouad RA, Enan ET, Attia MA, Afify MR, Zeidan NMS, Nashat M

Journal of Inflammation Research 2021, 14:265-266

Published Date: 4 February 2021

Neopterin: A Promising Candidate Biomarker for Severe COVID-19

Hailemichael W, Kiros M, Akelew Y, Getu S, Andualem H

Journal of Inflammation Research 2021, 14:245-251

Published Date: 2 February 2021

Clinical Implications of Intestinal Barrier Damage in Psoriasis

Sikora M, Stec A, Chrabaszcz M, Giebultowicz J, Samborowska E, Jazwiec R, Dadlez M, Olszewska M, Rudnicka L

Journal of Inflammation Research 2021, 14:237-243

Published Date: 27 January 2021

Nucleic Acid-Sensing Pathways During SARS-CoV-2 Infection: Expectations versus Reality

Mdkhana B, Saheb-Sharif Askari N, Ramakrishnan RK, Goel S, Hamid Q, Halwani R

Journal of Inflammation Research 2021, 14:199-216

Published Date: 26 January 2021

In vitro Phenotype Induction of Circulating Monocytes: CD16 and CD163 Analysis

Karsulovic C, Tempio F, Lopez M, Guerrero J, Goecke A

Journal of Inflammation Research 2021, 14:191-198

Published Date: 26 January 2021

Cytokine Storm and Mucus Hypersecretion in COVID-19: Review of Mechanisms

Khan MA, Khan ZA, Charles M, Pratap P, Naeem A, Siddiqui Z, Naqvi N, Srivastava S

Journal of Inflammation Research 2021, 14:175-189

Published Date: 22 January 2021

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

Krawiec P, Pac-Kożuchowska E

Journal of Inflammation Research 2021, 14:163-174

Published Date: 22 January 2021

Studying Neutrophil Function in vitro: Cell Models and Environmental Factors

Blanter M, Gouwy M, Struyf S

Journal of Inflammation Research 2021, 14:141-162

Published Date: 20 January 2021

Selenium-Containing Amino Acids Protect Dextran Sulfate Sodium-Induced Colitis via Ameliorating Oxidative Stress and Intestinal Inflammation

Shi C, Yue F, Shi F, Qin Q, Wang L, Wang G, Mu L, Liu D, Li Y, Yu T, She J

Journal of Inflammation Research 2021, 14:85-95

Published Date: 14 January 2021

The Role of Regulatory B Cells in Health and Diseases: A Systemic Review

Chekol Abebe E, Asmamaw Dejenie T, Mengie Ayele T, Dagnew Baye N, Agegnehu Teshome A, Tilahun Muche Z

Journal of Inflammation Research 2021, 14:75-84

Published Date: 12 January 2021

Inhibition of Dectin-1 on Dendritic Cells Prevents Maturation and Prolongs Murine Islet Allograft Survival

Ren A, Li Z, Zhang X, Deng R, Ma Y

Journal of Inflammation Research 2021, 14:63-73

Published Date: 12 January 2021

Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B

Fettucciari K, Fruganti A, Marchegiani A, Brancorsini S, Marconi P, Bassotti G

Journal of Inflammation Research 2021, 14:57-62

Published Date: 11 January 2021

Understanding COVID-19 Pandemic: Molecular Mechanisms and Potential Therapeutic Strategies. An Evidence-Based Review

Hanna R, Dalvi S, Sălăgean T, Pop ID, Bordea IR, Benedicenti S

Journal of Inflammation Research 2021, 14:13-56

Published Date: 7 January 2021

Potential Impact of Local Anesthetics Inducing Granulocyte Arrest and Altering Immune Functions on Perioperative Outcome

Kolle G, Metterlein T, Gruber M, Seyfried T, Petermichl W, Pfaehler SM, Bitzinger D, Wittmann S, Bredthauer A

Journal of Inflammation Research 2021, 14:1-12

Published Date: 6 January 2021