Matia-Garcia I, Vadillo E, Pelayo R, Muñoz-Valle JF, García-Chagollán M, Loaeza-Loaeza J, Vences-Velázquez A, Salgado-Goytia L, García-Arellano S, Parra-Rojas I

Journal of Inflammation Research 2021, 14:6587-6600

Published Date: 6 December 2021

Original Research

A Mixture of Lactobacillus fermentum HFY06 and Arabinoxylan Ameliorates Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis in Mice

Li F, Huang H, Zhu F, Zhou X, Yang Z, Zhao X

Journal of Inflammation Research 2021, 14:6575-6585

Published Date: 6 December 2021

Original Research

ARL14 as a Prognostic Biomarker in Non-Small Cell Lung Cancer

Zhang B, Xu A, Wu D, Xia W, Li P, Wang E, Han R, Sun P, Zhou S, Wang R

Journal of Inflammation Research 2021, 14:6557-6574

Published Date: 7 December 2021

Review

Progranulin as a Potential Therapeutic Target in Immune-Mediated Diseases

Lan YJ, Sam NB, Cheng MH, Pan HF, Gao J

Journal of Inflammation Research 2021, 14:6543-6556

Published Date: 4 December 2021

Original Research

1,25-Dihydroxyvitamin D Inhibits Osteoarthritis by Modulating Interaction Between Vitamin D Receptor and NLRP3 in Macrophages

Duan A, Ma Z, Liu W, Shen K, Zhou H, Wang S, Kong R, Shao Y, Chen Y, Guo W, Liu F

Journal of Inflammation Research 2021, 14:6523-6542

Published Date: 3 December 2021

Original Research

A Novel Clinical Radiomics Nomogram to Identify Crohn’s Disease from Intestinal Tuberculosis

Zhu C, Yu Y, Wang S, Wang X, Gao Y, Li C, Li J, Ge Y, Wu X

Journal of Inflammation Research 2021, 14:6511-6521

Published Date: 3 December 2021

Original Research

Interleukin -1β Promotes Lung Adenocarcinoma Growth and Invasion Through Promoting Glycolysis via p38 Pathway

Tan Q, Duan L, Huang Q, Chen W, Yang Z, Chen J, Jin Y

Journal of Inflammation Research 2021, 14:6491-6509

Published Date: 2 December 2021

Original Research

Methylglyoxal Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via RAGE-Induced ROS Generation: Protective Effects of Metformin

Medeiros ML, Oliveira AL, de Oliveira MG, Monica FZ, Antunes E

Journal of Inflammation Research 2021, 14:6477-6489

Published Date: 2 December 2021

Original Research

Investigation of Association of Complement 5 Genetic Polymorphisms with Sepsis and Sepsis-Induced Inflammatory Responses

Chen K, Lin Y, Liu Y, Liao S, Yang R, Huang J, Xu M, He J

Journal of Inflammation Research 2021, 14:6461-6475

Published Date: 2 December 2021

Original Research

Construction of ceRNA Network to Reveal Potential Biomarkers in Crohn’s Disease and Validation in a TNBS Induced Mice Model

Ye C, Zhu S, Yuan J

Journal of Inflammation Research 2021, 14:6447-6459

Published Date: 2 December 2021

Original Research

The Differential Expression of the Inflammasomes in Adipose Tissue and Colon Influences the Development of Colon Cancer in a Context of Obesity by Regulating Intestinal Inflammation

Frühbeck G, Mentxaka A, Ahechu P, Gómez-Ambrosi J, Ramírez B, Becerril S, Rodríguez A, Unamuno X, Cienfuegos JA, Casado M, Burrell MA, Martín M, Baixauli J, Valentí V, Moncada R, Reina G, Silva C, Catalán V

Journal of Inflammation Research 2021, 14:6431-6446

Published Date: 1 December 2021

Original Research

Upregulation of TMEM45A Promoted the Progression of Clear Cell Renal Cell Carcinoma in vitro

Jiang H, Chen H, Wan P, Liang M, Chen N

Journal of Inflammation Research 2021, 14:6421-6430

Published Date: 1 December 2021

Original Research

Combined Use of Fecal Biomarkers in Inflammatory Bowel Diseases: Oncostatin M and Calprotectin

Cao Y, Dai Y, Zhang L, Wang D, Hu W, Yu Q, Wang X, Yu P, Liu W, Ping Y, Sun T, Sang Y, Liu Z, Chen Y, Tao Z

Journal of Inflammation Research 2021, 14:6409-6419

Published Date: 1 December 2021

Original Research

Circular RNA Foxo3 Relieves Myocardial Ischemia/Reperfusion Injury by Suppressing Autophagy via Inhibiting HMGB1 by Repressing KAT7 in Myocardial Infarction

Sun G, Shen JF, Wei XF, Qi GX

Journal of Inflammation Research 2021, 14:6397-6407

Published Date: 1 December 2021

Review

Indeterminate Colitis – Update on Treatment Options

Venkateswaran N, Weismiller S, Clarke K

Journal of Inflammation Research 2021, 14:6383-6395

Published Date: 30 November 2021

Review

Common Inflammatory Mechanisms in COVID-19 and Parkinson’s Diseases: The Role of Microbiome, Pharmabiotics and Postbiotics in Their Prevention

Danilenko V, Devyatkin A, Marsova M, Shibilova M, Ilyasov R, Shmyrev V

Journal of Inflammation Research 2021, 14:6349-6381

Published Date: 30 November 2021

Original Research

PLIN2 Mediates Neuroinflammation and Oxidative/Nitrosative Stress via Downregulating Phosphatidylethanolamine in the Rostral Ventrolateral Medulla of Stressed Hypertensive Rats

Zhang S, Hu L, Han C, Huang R, Ooi K, Qian X, Ren X, Chu D, Zhang H, Du D, Xia C

Journal of Inflammation Research 2021, 14:6331-6348

Published Date: 30 November 2021

Original Research

Cross-Talk Between Nitrosative Stress, Inflammation and Hypoxia-Inducible Factor in Patients with Adrenal Masses

Choromańska B, Myśliwiec P, Kozłowski T, Łuba M, Wojskowicz P, Dadan J, Myśliwiec H, Choromańska K, Makarewicz K, Zalewska A, Maciejczyk M

Journal of Inflammation Research 2021, 14:6317-6330

Published Date: 30 November 2021

Original Research

Garlic Extract Alleviates Trastuzumab-Induced Hepatotoxicity in Rats Through Its Antioxidant, Anti-Inflammatory, and Antihyperlipidemic Effects

Mousa AM, Soliman KEA, Alhumaydhi F, Almatroudi A, Al Rugaie O, Allemailem KS, Alrumaihi F, Khan A, Rezk MY, Aljasir M, Alwashmi ASS, Aba Alkhayl FF, Albutti AS, Seleem HS

Journal of Inflammation Research 2021, 14:6305-6316

Published Date: 27 November 2021

Original Research

Toll-Like Receptor 4 Polymorphisms (896A/G and 1196C/T) as an Indicator of COVID-19 Severity in a Convenience Sample of Egyptian Patients

Taha SI, Shata AK, Baioumy SA, Fouad SH, Anis SG, Mossad IM, Moustafa NM, Abdou DM, Youssef MK

Journal of Inflammation Research 2021, 14:6293-6303

Published Date: 27 November 2021

Original Research

LncRNAs Associated with Chemoradiotherapy Response and Prognosis in Locally Advanced Rectal Cancer

Zhang Y, Guan B, WU Y, Du F, Zhuang J, Yang Y, Guan G, Liu X

Journal of Inflammation Research 2021, 14:6275-6292

Published Date: 27 November 2021

Original Research

A Web-Based Survey on Factors for Unvaccination and Adverse Reactions of SARS-CoV-2 Vaccines in Chinese Patients with Psoriasis

Wang Q, Lv C, Han X, Shen M, Kuang Y

Journal of Inflammation Research 2021, 14:6265-6273

Published Date: 27 November 2021

Review

Melatonin as a Potential Regulator of Oxidative Stress, and Neuroinflammation: Mechanisms and Implications for the Management of Brain Injury-Induced Neurodegeneration

Ikram M, Park HY, Ali T, Kim MO

Journal of Inflammation Research 2021, 14:6251-6264

Published Date: 27 November 2021

Original Research

Direct CCL4 Inhibition Modulates Gut Microbiota, Reduces Circulating Trimethylamine N-Oxide, and Improves Glucose and Lipid Metabolism in High-Fat-Diet-Induced Diabetes Mellitus

Chang TT, Chen JW

Journal of Inflammation Research 2021, 14:6237-6250

Published Date: 27 November 2021

Original Research

Gasdermin D in Different Subcellular Locations Predicts Diverse Progression, Immune Microenvironment and Prognosis in Colorectal Cancer

Wang J, Kang Y, Li Y, Sun L, Zhang J, Qian S, Luo K, Jiang Y, Sun L, Xu F

Journal of Inflammation Research 2021, 14:6223-6235

Published Date: 25 November 2021

Review

SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases

Murugan AK, Alzahrani AS

Journal of Inflammation Research 2021, 14:6191-6221

Published Date: 24 November 2021

Original Research

Gut and Cutaneous Microbiome Featuring Abundance of Lactobacillus reuteri Protected Against Psoriasis-Like Inflammation in Mice

Chen HL, Zeng YB, Zhang ZY, Kong CY, Zhang SL, Li ZM, Huang JT, Xu YY, Mao Y, Cai PR, Han B, Wang WQ, Wang LS

Journal of Inflammation Research 2021, 14:6175-6190

Published Date: 24 November 2021

Corrigendum

Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice [Corrigendum]

Huang C, Cai J, Jin S, Lin Q, Fang Q, Nan K, Han Y, Ge W, Liu Y, Tao Y, Cao H, Li J

Journal of Inflammation Research 2021, 14:6173-6174

Published Date: 24 November 2021

Original Research

Mesenchymal Stem Cell–Originated Exosomal Circular RNA circFBXW7 Attenuates Cell Proliferation, Migration and Inflammation of Fibroblast-Like Synoviocytes by Targeting miR-216a-3p/HDAC4 in Rheumatoid Arthritis

Chang L, Kan L

Journal of Inflammation Research 2021, 14:6157-6171

Published Date: 24 November 2021

Original Research

Identification of Unique Transcriptomic Signatures and Hub Genes Through RNA Sequencing and Integrated WGCNA and PPI Network Analysis in Nonerosive Reflux Disease

Zhao Y, Ma T, Zou D

Journal of Inflammation Research 2021, 14:6143-6156

Published Date: 23 November 2021

Original Research

Evaluation of Predictive Values of Naples Prognostic Score in Patients with Unresectable Stage III Non-Small Cell Lung Cancer

Guo D, Liu J, Li Y, Li C, Liu Q, Ji S, Zhu S

Journal of Inflammation Research 2021, 14:6129-6141

Published Date: 23 November 2021

Original Research

Association Between Pre-Treatment and Post-Treatment 3-Month Red Cell Distribution Width with Three-Year Prognosis of Prostate Cancer

Cheng J, Wang S, Jia J, Chen Q, Song Y, Li J

Journal of Inflammation Research 2021, 14:6115-6127

Published Date: 23 November 2021

Original Research

IL-6 Quotient (The Ratio of Cerebrospinal Fluid IL-6 to Serum IL-6) as a Biomarker of an Unruptured Intracranial Aneurysm

Kamińska J, Dymicka-Piekarska V, Chrzanowski R, Sawicki K, Milewska AJ, Zińczuk J, Tylicka M, Jadeszko M, Mariak Z, Kratz EM, Matowicka-Karna J, Kornhuber J, Lewczuk P, Koper-Lenkiewicz OM

Journal of Inflammation Research 2021, 14:6103-6114

Published Date: 23 November 2021

Original Research

Whole Blood Expression Pattern of Inflammation and Redox Genes in Mild Alzheimer’s Disease

Milanesi E, Dobre M, Cucos CA, Rojo AI, Jiménez-Villegas J, Capetillo-Zarate E, Matute C, Piñol-Ripoll G, Manda G, Cuadrado A

Journal of Inflammation Research 2021, 14:6085-6102

Published Date: 20 November 2021

Original Research

Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3

Jin Y, Li Z, Wu Y, Li H, Liu Z, Liu L, Ouyang N, Zhou T, Fang B, Xia L

Journal of Inflammation Research 2021, 14:6067-6083

Published Date: 19 November 2021

Original Research

Phenotypes, Lung Microbiota and Cytokine Responses in Pneumonia After Hematopoietic Stem Cell Transplantation

Hu Y, Jiang Y, Liu S, Shen J, An Y

Journal of Inflammation Research 2021, 14:6055-6065

Published Date: 19 November 2021

Original Research

The Network of Pro-Inflammatory Factors CD147, DcR3, and IL33 in the Development of Kawasaki Disease

Qi Y, Xu J, Lin Z, Tao Y, Zheng F, Wang Y, Sun Y, Fu S, Wang W, Xie C, Zhang Y, Gong F

Journal of Inflammation Research 2021, 14:6043-6053

Published Date: 19 November 2021

Review

The Immunomodulatory Functions of Butyrate

Siddiqui MT, Cresci GAM

Journal of Inflammation Research 2021, 14:6025-6041

Published Date: 18 November 2021

Original Research

Altered Pattern of Macrophage Polarization as a Biomarker for Severity of Childhood Asthma

Kuo CH, Tsai ML, Li CH, Hsiao HP, Chao MC, Lee MS, Lin YC, Hung CH

Journal of Inflammation Research 2021, 14:6011-6023

Published Date: 18 November 2021

Original Research

Transcriptome Sequencing Explores the Mechanism of Baicalin on Bone Cancer Pain

Wang A, Guo D, Cheng H, Jiang H, Liu X, Yun Z

Journal of Inflammation Research 2021, 14:5999-6010

Published Date: 16 November 2021

Original Research

IL-33/ST2 Axis Deficiency Exacerbates Hepatic Pathology by Regulating Treg and Th17 Cells in Murine Schistosomiasis Japonica

Bai Y, Guan F, Zhu F, Jiang C, Xu X, Zheng F, Liu W, Lei J

Journal of Inflammation Research 2021, 14:5981-5998

Published Date: 15 November 2021

Original Research

A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population

Wu SE, Chen WL

Journal of Inflammation Research 2021, 14:5969-5980

Published Date: 16 November 2021

Original Research

Thrombospondin 2 Promotes IL-6 Production in Osteoarthritis Synovial Fibroblasts via the PI3K/AKT/NF-κB Pathway

Hou CH, Tang CH, Chen PC, Liu JF

Journal of Inflammation Research 2021, 14:5955-5967

Published Date: 13 November 2021

Review

Mucin-Type O-Glycans: Barrier, Microbiota, and Immune Anchors in Inflammatory Bowel Disease

Zhang Y, Wang L, Ocansey DKW, Wang B, Wang L, Xu Z

Journal of Inflammation Research 2021, 14:5939-5953

Published Date: 13 November 2021

Original Research

Melatonin Ameliorates Axonal Hypomyelination of Periventricular White Matter by Transforming A1 to A2 Astrocyte via JAK2/STAT3 Pathway in Septic Neonatal Rats

Jiang S, Wang H, Zhou Q, Li Q, Liu N, Li Z, Chen C, Deng Y

Journal of Inflammation Research 2021, 14:5919-5937

Published Date: 12 November 2021

Original Research

Clock Gene Nr1d1 Alleviates Retinal Inflammation Through Repression of Hmga2 in Microglia

Wang Z, Huang Y, Chu F, Ji S, Liao K, Cui Z, Chen J, Tang S

Journal of Inflammation Research 2021, 14:5901-5918

Published Date: 11 November 2021

Original Research

Predicting Neoadjuvant Chemoradiotherapy Response in Locally Advanced Rectal Cancer Using Tumor-Infiltrating Lymphocytes Density

Xu Y, Lou X, Liang Y, Zhang S, Yang S, Chen Q, Xu Z, Zhao M, Li Z, Zhao K, Liu Z

Journal of Inflammation Research 2021, 14:5891-5899

Published Date: 10 November 2021

Original Research

circ_TGFBR2 Inhibits Vascular Smooth Muscle Cells Phenotypic Switch and Suppresses Aortic Dissection Progression by Sponging miR-29a

Xu Z, Zhong K, Guo G, Xu C, Song Z, Wang D, Pan J

Journal of Inflammation Research 2021, 14:5877-5890

Published Date: 9 November 2021

Original Research

The Anti-Inflammation and Anti-Nociception Effect of Ketoprofen in Rats Could Be Strengthened Through Co-Delivery of a H2S Donor, S-Propargyl-Cysteine

Yu Y, Yang Q, Wang Z, Ding Q, Li M, Fang Y, He Q, Zhu YZ

Journal of Inflammation Research 2021, 14:5863-5875

Published Date: 9 November 2021

Original Research

Bacterial Lipopolysaccharide Augmented Malignant Transformation and Promoted the Stemness in Prostate Cancer Epithelial Cells

Tang S, Lian X, Cheng H, Guo J, Ni D, Huang C, Gu X, Meng H, Jiang J, Li X

Journal of Inflammation Research 2021, 14:5849-5862

Published Date: 9 November 2021

Original Research

Could Mesna and Celery Seed Cotherapy Modulate Oxidative Stress and Inflammation of the Urinary Bladder Induced by Ifosfamide in Rabbits?

Mousa AM, Allemailem KS, Alhumaydhi FA, Alrumaihi F, Almatroudi A, Alwashmi AS, Aljasir M, Al Rugaie O, Aljohani ASM, Soliman KEA, Rezk MY, Hegazy AMS, Seleem HS

Journal of Inflammation Research 2021, 14:5837-5847

Published Date: 8 November 2021

Original Research

The Relationship Between Ambient Air Pollution and Hospitalizations for Gout in a Humid Subtropical Region of China

He YS, Wang GH, Wu Q, Wu ZD, Chen Y, Tao JH, Fang XY, Xu Z, Pan HF

Journal of Inflammation Research 2021, 14:5827-5835

Published Date: 4 November 2021

Original Research

Higher Serum Leptin Levels are Associated with a Reduced Risk of Sarcopenia but a Higher Risk of Dynapenia Among Older Adults

Kao TW, Peng TC, Chen WL, Chi YC, Chen CL, Yang WS

Journal of Inflammation Research 2021, 14:5817-5825

Published Date: 3 November 2021

Original Research

Syndecan-1 Shedding by Matrix Metalloproteinase-9 Signaling Regulates Alveolar Epithelial Tight Junction in Lipopolysaccharide-Induced Early Acute Lung Injury

Zhang D, Zhang JT, Pan Y, Liu XF, Xu JW, Cui WJ, Qiao XR, Dong L

Journal of Inflammation Research 2021, 14:5801-5816

Published Date: 4 November 2021

Review

Long Non-Coding RNAs in Oral Submucous Fibrosis: Their Functional Mechanisms and Recent Research Progress

He Y, Wang W, Jiang P, Yang L, Guo Q, Xiang J, Gao Y, Wang Y, Chen R

Journal of Inflammation Research 2021, 14:5787-5800

Published Date: 3 November 2021

Original Research

The Efficacy of Different Inflammatory Markers for the Prognosis of Patients with Malignant Tumors

Zheng K, Liu X, Ji W, Lu J, Cui J, Li W

Journal of Inflammation Research 2021, 14:5769-5785

Published Date: 3 November 2021

Short Report

Aged IRF3-KO Mice are Protected from Sepsis

Goswami DG, Walker WE

Journal of Inflammation Research 2021, 14:5757-5767

Published Date: 3 November 2021

Original Research

Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced Rat Paw Edema Test

Szandruk-Bender M, Merwid-Ląd A, Wiatrak B, Danielewski M, Dzimira S, Szkudlarek D, Szczukowski Ł, Świątek P, Szeląg A

Journal of Inflammation Research 2021, 14:5739-5756

Published Date: 2 November 2021

Review

Neuroinflammation and Modulation Role of Natural Products After Spinal Cord Injury

Wu X, Yan Y, Zhang Q

Journal of Inflammation Research 2021, 14:5713-5737

Published Date: 2 November 2021

Original Research

Regulation of the Immune Microenvironment by an NLRP3 Inhibitor Contributes to Attenuation of Acute Right Ventricular Failure in Rats with Pulmonary Arterial Hypertension

Guo L, Qin G, Cao Y, Yang Y, Dai S, Wang L, Wang E

Journal of Inflammation Research 2021, 14:5699-5711

Published Date: 2 November 2021

Original Research

Genetic Polymorphisms in NLRP3 Inflammasome-Associated Genes in Patients with B-Cell Non-Hodgkin’s Lymphoma

Liu ZH, Zhang L, Jing FJ, Xiao SX, Gao Y, Bian HY, Zhao X

Journal of Inflammation Research 2021, 14:5687-5697

Published Date: 1 November 2021

Original Research

Linagliptin Inhibits Interleukin-6 Production Through Toll-Like Receptor 4 Complex and Lipopolysaccharide-Binding Protein Independent Pathway in vitro Model

Saito H, Nakamura Y, Inagaki M, Yamadera S, Misawa H, Sato N, Oguchi T, Inagaki T, Tsuji Y, Tsuji M, Ohsawa I, Gotoh H, Kiuchi Y

Journal of Inflammation Research 2021, 14:5681-5686

Published Date: 2 November 2021

Original Research

Investigation of 1, 3, 4 Oxadiazole Derivative in PTZ-Induced Neurodegeneration: A Simulation and Molecular Approach

Faheem M, Althobaiti YS, Khan AW, Ullah A, Ali SH, Ilyas U

Journal of Inflammation Research 2021, 14:5659-5679

Published Date: 1 November 2021

Rapid Communication

Caffeic Acid Phenethyl Ester reduces Pro Inflammatory Cytokines in Moderate Swimming Test in Growing Rats Model

Al-Hariri M, Alsunni A, Shaikh MH, Gamal Eldin T, Al Ghamdi K, Alharbi AF, Alhawaj H, Chathoth S

Journal of Inflammation Research 2021, 14:5653-5657

Published Date: 1 November 2021

Original Research

Predictive Value of the Platelet-to-Albumin Ratio (PAR) on the Risk of Death at Admission in Patients Suffering from Severe Fever with Thrombocytopenia Syndrome

Gui Y, Xu Y, Yang P

Journal of Inflammation Research 2021, 14:5647-5652

Published Date: 29 October 2021

Original Research

Peripheral Lymphocyte Subsets Absolute Counts as Feasible Clinical Markers for Predicting Surgical Outcome in Gastric Cancer Patients After Laparoscopic D2 Gastrectomy: A Prospective Cohort Study

Dan Zeng CD, Tong YX, Xiao AT, Gao C, Zhang S

Journal of Inflammation Research 2021, 14:5633-5646

Published Date: 29 October 2021

Original Research

Alteration of the Immune Microenvironment in HBsAg and HBeAg Dual-Positive Pregnant Women Presenting a High HBV Viral Load

Gao F, Wang H, Li X, Guo F, Yuan Y, Wang X, Zhang Y, Bai G

Journal of Inflammation Research 2021, 14:5619-5632

Published Date: 29 October 2021

Review

Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19

Zou Y, Meng Z

Journal of Inflammation Research 2021, 14:5611-5618

Published Date: 1 November 2021

Original Research

Crosstalk between Circulatory Microenvironment and Vascular Endothelial Cells in Acute Myocardial Infarction

Lin B, Zheng W, Jiang X

Journal of Inflammation Research 2021, 14:5597-5610

Published Date: 29 October 2021

Original Research

Transthyretin and Receptor for Advanced Glycation End Product’s Differential Levels Associated with the Pathogenesis of Rheumatoid Arthritis

Monu, Agnihotri P, Saquib M, Sarkar A, Chakraborty D, Kumar U, Biswas S

Journal of Inflammation Research 2021, 14:5581-5596

Published Date: 28 October 2021

Original Research

Investigation of Wound Healing and Anti-Inflammatory Activities of Leaf Gel of Aloe trigonantha L.C. Leach in Rats

Tazeze H, Mequanente S, Nigussie D, Legesse B, Makonnen E, Mengie T

Journal of Inflammation Research 2021, 14:5567-5580

Published Date: 28 October 2021

Original Research

Curcumae Ameliorates Diethylnitrosamine-Induced Hepatocellular Carcinoma via Alteration of Oxidative Stress, Inflammation and Gut Microbiota

Zhang Y, Li X, Li X

Journal of Inflammation Research 2021, 14:5551-5566

Published Date: 27 October 2021

Original Research

Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice

Liu B, Xie Y, Chen J, Xue J, Zhang X, Zhao M, Jia X, Wang Y, Qin S

Journal of Inflammation Research 2021, 14:5541-5550

Published Date: 27 October 2021

Original Research

Association of Systemic Inflammation and Overall Survival in Elderly Patients with Cancer Cachexia – Results from a Multicenter Study

Ruan GT, Yang M, Zhang XW, Song MM, Hu CL, Ge YZ, Xie HL, Liu T, Tang M, Zhang Q, Zhang X, Zhang KP, Li XR, Li QQ, Chen YB, Yu KY, Cong MH, Wang KH, Shi HP

Journal of Inflammation Research 2021, 14:5527-5540

Published Date: 27 October 2021

Commentary

IgE and TGF-β Signaling: From Immune to Cardiac Remodeling

Cao H, Xiao C, He Z, Huang H, Tang H

Journal of Inflammation Research 2021, 14:5523-5526

Published Date: 27 October 2021

Original Research

The Value of Prognostic Nutritional Index (PNI) on Newly Diagnosed Diffuse Large B-Cell Lymphoma Patients: A Multicenter Retrospective Study of HHLWG Based on Propensity Score Matched Analysis

Shen Z, Wang F, He C, Li D, Nie S, Bian Z, Yao M, Xue Y, Wang Y, Gu W, Zhu T, Shi Y, Zhang H, Huang S, Miao Y, Sang W

Journal of Inflammation Research 2021, 14:5513-5522

Published Date: 27 October 2021

Original Research

Albumin/Globulin Ratio as Yin–Yang in Rheumatoid Arthritis and Its Correlation to Inflamm-Aging Cytokines

Chen Y, Chen Y, Zhao L, He H, Wei L, Lai W, Yuan J, Hong X, Liu L, Wang B, Nandakumar KS, Liu D

Journal of Inflammation Research 2021, 14:5501-5511

Published Date: 27 October 2021

Original Research

Exosomal lncRNA HOTTIP Mediates Antiviral Effect of Tenofovir Alafenamide (TAF) on HBV Infection

Liu QM, He YY, Liu LL, Wang LK

Journal of Inflammation Research 2021, 14:5489-5500

Published Date: 23 October 2021

Review

Comparison of the Characteristics of Cytokine Storm and Immune Response Induced by SARS-CoV, MERS-CoV, and SARS-CoV-2 Infections

Liu T, Feng M, Wen Z, He Y, Lin W, Zhang M

Journal of Inflammation Research 2021, 14:5475-5487

Published Date: 23 October 2021

Corrigendum

Overexpression of Lin28a Aggravates Psoriasis-Like Phenotype by Regulating the Proliferation and Differentiation of Keratinocytes [Corrigendum]

Jang S, Jang S, Kim SY, Ko J, Kim E, Park JY, Hyung H, Lee JH, Lim SG, Park S, Yi J, Lee HJ, Kim MO, Lee HS, Ryoo ZY

Journal of Inflammation Research 2021, 14:5473-5474

Published Date: 22 October 2021

Review

The Adverse Impact of Incense Smoke on Human Health: From Mechanisms to Implications

Lee CW, Vo TTT, Wee Y, Chiang YC, Chi MC, Chen ML, Hsu LF, Fang ML, Lee KH, Guo SE, Cheng HC, Lee IT

Journal of Inflammation Research 2021, 14:5451-5472

Published Date: 22 October 2021

Original Research

A Multidisciplinary Team Approach to the Treatment of Liver Cirrhosis

Zhang YR, Wang H, Zhou N, Zhang YD, Lin Y, Wu LY, Wei SF, Ma YY, Wang CX

Journal of Inflammation Research 2021, 14:5443-5450

Published Date: 22 October 2021

Original Research

Immune Dysfunction is Associated with Readmission in Survivors of Sepsis Following Infected Pancreatic Necrosis

Yin J, Mao W, Xiao X, Yu X, Li B, Chen F, Lin J, Zhou J, Zhou J, Tong Z, Ke L, Li W

Journal of Inflammation Research 2021, 14:5433-5442

Published Date: 20 October 2021

Original Research

Atherosclerosis Pathways are Activated in Pericoronary Adipose Tissue of Patients with Coronary Artery Disease

Konwerski M, Gromadka A, Arendarczyk A, Koblowska M, Iwanicka-Nowicka R, Wilimski R, Czub P, Filipiak KJ, Hendzel P, Zielenkiewicz P, Opolski G, Gąsecka A, Mazurek T

Journal of Inflammation Research 2021, 14:5419-5431

Published Date: 20 October 2021

Original Research

Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression

Zhang Y, Zhang X, Jin Z, Chen H, Zhang C, Wang W, Jing J, Pan W

Journal of Inflammation Research 2021, 14:5403-5417

Published Date: 20 October 2021

Original Research

Ferroptosis is Involved in Hyperoxic Lung Injury in Neonatal Rats

Jia D, Zheng J, Zhou Y, Jia J, Ye X, Zhou B, Chen X, Mo Y, Wang J

Journal of Inflammation Research 2021, 14:5393-5401

Published Date: 18 October 2021

Original Research

The Predictive Value of Hemocytometry Based on Peripheral Platelet-Related Parameters in Identifying the Causes of Febrile Seizures

Tang L, Chen JR

Journal of Inflammation Research 2021, 14:5381-5392

Published Date: 18 October 2021

Original Research

B-Cell Deficiency Exacerbates Inflammation and Bone Loss in Ligature-Induced Experimental Periodontitis in Mice

Zeng W, Liu G, Luan Q, Yang C, Li S, Yu X, Su L

Journal of Inflammation Research 2021, 14:5367-5380

Published Date: 15 October 2021

Review

Between Inflammation and Autophagy: The Role of Leptin-Adiponectin Axis in Cardiac Remodeling

Kamareddine L, Ghantous CM, Allouch S, Al-Ashmar SA, Anlar G, Kannan S, Djouhri L, Korashy HM, Agouni A, Zeidan A

Journal of Inflammation Research 2021, 14:5349-5365

Published Date: 16 October 2021

Original Research

A Novel Modified-Curcumin Promotes Resolvin-Like Activity and Reduces Bone Loss in Diabetes-Induced Experimental Periodontitis

Deng J, Golub LM, Lee HM, Raja V, Johnson F, Kucine A, Lee W, Xu TM, Gu Y

Journal of Inflammation Research 2021, 14:5337-5347

Published Date: 16 October 2021

Clinical Trial Report

Proprotein Convertase Subtilisin/Kexin Type 9 and Systemic Inflammatory Biomarker Pentraxin 3 for Risk Stratification Among STEMI Patients Undergoing Primary PCI

Zhao X, Song L, Wang Y, Li J, Zhou J, Chen R, Liu C, Zhou P, Sheng Z, Chen Y, Zhao H, Yan H

Journal of Inflammation Research 2021, 14:5319-5335

Published Date: 14 October 2021

Original Research

SJMHE1 Peptide from Schistosoma japonicum Inhibits Asthma in Mice by Regulating Th17/Treg Cell Balance via miR-155

Li L, Shan W, Zhu H, Xue F, Ma Y, Dong L, Feng D, Mao J, Yuan G, Wang X

Journal of Inflammation Research 2021, 14:5305-5318

Published Date: 14 October 2021

Original Research

Capsaicin Protects Against Lipopolysaccharide-Induced Acute Lung Injury Through the HMGB1/NF-κB and PI3K/AKT/mTOR Pathways

Chen H, Li N, Zhan X, Zheng T, Huang X, Chen Q, Song Z, Yang F, Nie H, Zhang Y, Zheng B, Gong Q

Journal of Inflammation Research 2021, 14:5291-5304

Published Date: 14 October 2021

Review

The Multiple Roles of Fibroblast Growth Factor in Diabetic Nephropathy

Deng J, Liu Y, Liu Y, Li W, Nie X

Journal of Inflammation Research 2021, 14:5273-5290

Published Date: 14 October 2021

Review

New Horizons for the Roles and Association of APE1/Ref-1 and ABCA1 in Atherosclerosis

Chen W, Wang S, Xing D

Journal of Inflammation Research 2021, 14:5251-5271

Published Date: 14 October 2021

Original Research

Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages

Lai CY, Tseng PC, Chen CL, Satria RD, Wang YT, Lin CF

Journal of Inflammation Research 2021, 14:5241-5249

Published Date: 13 October 2021

Original Research

Distinct Polarization Dynamics of Microglia and Infiltrating Macrophages: A Novel Mechanism of Spinal Cord Ischemia/Reperfusion Injury

Li H, Wang P, Tang L, Sun J, Zhang Y, Luo W, Luo C, Hu Z, Yang L

Journal of Inflammation Research 2021, 14:5227-5239

Published Date: 13 October 2021

Original Research

Gut Microbiota Contributes to Host Defense Against Klebsiella pneumoniae-Induced Liver Abscess

Zheng Y, Ding Y, Xu M, Chen H, zhang H, Liu Y, Shen W, Li J

Journal of Inflammation Research 2021, 14:5215-5225

Published Date: 9 October 2021

Original Research

Investigating Associations Between Depressive Symptoms and Anti-/Pro-Inflammatory Nutrients in an Elderly Population in Northern China: A Bayesian Kernel Machine Regression Approach

Li R, Zhan W, Huang X, Zhang L, Sun Y, Zhang Z, Bao W, Ma Y

Journal of Inflammation Research 2021, 14:5201-5213

Published Date: 9 October 2021

Review

Interferon-Driven Immune Dysregulation in Down Syndrome: A Review of the Evidence

Chung H, Green PH, Wang TC, Kong XF

Journal of Inflammation Research 2021, 14:5187-5200

Published Date: 7 October 2021

Response to Letter

A Role for Mucolytics and Expectorants in Aiding Inhaled Therapies in Asthma? [Response To Letter]

Kurukulaaratchy RJ, Rupani H, Fong WCG, Kyyaly A

Journal of Inflammation Research 2021, 14:5183-5185

Published Date: 8 October 2021

Original Research

β-Nicotinamide Mononucleotide (NMN) Administrated by Intraperitoneal Injection Mediates Protection Against UVB-Induced Skin Damage in Mice

Zhou X, Du HH, Long X, Pan Y, Hu J, Yu J, Zhao X

Journal of Inflammation Research 2021, 14:5165-5182

Published Date: 7 October 2021

Original Research

Altered T-Cell Subsets are Associated with Dysregulated Cytokine Secretion of CD4+ T Cells During HIV Infection

Wang D, Jiang Y, Song Y, Zeng Y, Li C, Wang X, Liu Y, Xiao J, Kong Y, Zhao H

Journal of Inflammation Research 2021, 14:5149-5163

Published Date: 7 October 2021

Original Research

Platelet Mediated Inflammation in Coronary Artery Disease with Type 2 Diabetes Patients

Johny E, Bhaskar P, Alam MJ, Kuladhipati I, Das R, Adela R

Journal of Inflammation Research 2021, 14:5131-5147

Published Date: 7 October 2021

Original Research

Clinical Value of C-Reactive Protein/Platelet Ratio in Neonatal Sepsis: A Cross-Sectional Study

Li X, Li T, Wang J, Feng Y, Ren C, Xu Z, Yang J, Zhang Q, An C

Journal of Inflammation Research 2021, 14:5123-5129

Published Date: 6 October 2021

Original Research

Preventive Effect of Flavonoid Extract from the Peel of Gonggan (Citrus reticulata Blanco Var. Gonggan) on CCl4-Induced Acute Liver Injury in Mice

Wu Y, He Y, Wang R, Zhao X

Journal of Inflammation Research 2021, 14:5111-5121

Published Date: 5 October 2021

Original Research

Maternal High-Fat Diet Programs Renal Peroxisomes and Activates NLRP3 Inflammasome-Mediated Pyroptosis in the Rat Fetus

Zhou P, Guan H, Guo Y, Zhu L, Liu X

Journal of Inflammation Research 2021, 14:5095-5110

Published Date: 5 October 2021

Original Research

The β3/5 Integrin-MMP9 Axis Regulates Pulmonary Inflammatory Response and Endothelial Leakage in Acute Lung Injury

Tong Y, Bao C, Xu YQ, Tao L, Zhou Y, Zhuang L, Meng Y, Zhang H, Xue J, Wang W, Zhang L, Pan Q, Shao Z, Hu T, Guo Q, Xue Q, Lu H, Luo Y

Journal of Inflammation Research 2021, 14:5079-5094

Published Date: 5 October 2021

Review

Diagnostic and Prognostic Value of Immune/Inflammation Biomarkers for Venous Thromboembolism: Is It Reliable for Clinical Practice?

Xue J, Ma D, Jiang J, Liu Y

Journal of Inflammation Research 2021, 14:5059-5077

Published Date: 2 October 2021

Original Research

Expression and Correlation of IgG4 and IL-21 in Collagen-Induced Arthritis Rats

Long ZY, Zhou YF, Yuan H, Peng YM, Wu SX, Peng F

Journal of Inflammation Research 2021, 14:5051-5058

Published Date: 1 October 2021

Review

Non-Coding RNAs: Master Regulators of Inflammasomes in Inflammatory Diseases

Wang W, Yang N, Yang YH, Wen R, Liu CF, Zhang TN

Journal of Inflammation Research 2021, 14:5023-5050

Published Date: 30 September 2021

Original Research

Clinical Values of miR-23a-3p in Oral Lichen Planus and Its Role in Keratinocyte Proliferation and Inflammatory Response

Wang J, Hu M, Li L

Journal of Inflammation Research 2021, 14:5013-5021

Published Date: 29 September 2021

Original Research

Effects of Berberine on the Chondrogenic Differentiation of Embryonic Limb Skeletal Progenitors

Duarte-Olivenza C, Montero JA, Lorda-Diez CI

Journal of Inflammation Research 2021, 14:5001-5011

Published Date: 29 September 2021

Original Research

Colocalization with MMP-7 in the Distal Colon is Crucial for Syndecan-2 Shedding in Dextran Sulfate Sodium-Induced Colitis Mice

Hong H, Song HK, Jang B, Park E, Han DS, Kim SE, Oh ES

Journal of Inflammation Research 2021, 14:4987-5000

Published Date: 29 September 2021

Original Research

Development of an Interferon Gamma Response-Related Signature for Prediction of Survival in Clear Cell Renal Cell Carcinoma

Liu L, Du X, Fang J, Zhao J, Guo Y, Zhao Y, Zou C, Yan X, Li W

Journal of Inflammation Research 2021, 14:4969-4985

Published Date: 27 September 2021

Original Research

Circulating Inflammation Markers Partly Explain the Link Between the Dietary Inflammatory Index and Depressive Symptoms

Gialluisi A, Santonastaso F, Bonaccio M, Bracone F, Shivappa N, Hebert JR, Cerletti C, Donati MB, de Gaetano G, Iacoviello L

Journal of Inflammation Research 2021, 14:4955-4968

Published Date: 28 September 2021

Original Research

Association Between Micronutrient Concentrations and Human Epididymis Protein 4

Lim ZW, Chen WL

Journal of Inflammation Research 2021, 14:4945-4954

Published Date: 27 September 2021

Original Research

TILRR (Toll-like Interleukin-1 Receptor Regulator), an Important Modulator of Inflammatory Responsive Genes, is Circulating in the Blood

Kashem MA, Yuan XY, Li L, Kimani J, Plummer F, Luo M

Journal of Inflammation Research 2021, 14:4927-4943

Published Date: 24 September 2021

Original Research

Transcription Coactivator BCL3 Acts as a Potential Regulator of Lipid Metabolism Through the Effects on Inflammation

Zhang S, Gao J, Liu S, Yu L, Zhang W, Liang Y, Wang H

Journal of Inflammation Research 2021, 14:4915-4926

Published Date: 23 September 2021

Original Research

In vivo Pharmacokinetic and Anticancer Studies of HH-N25, a Selective Inhibitor of Topoisomerase I, and Hormonal Signaling for Treating Breast Cancer

Lawal B, Kuo YC, Sumitra MR, Wu ATH, Huang HS

Journal of Inflammation Research 2021, 14:4901-4913

Published Date: 22 September 2021

Original Research

Angiogenesis Biomarkers in Ischemic Stroke Patients

Alrafiah A, Alofi E, Almohaya Y, Hamami A, Qadah T, Almaghrabi S, Hakami N, Alrawaili MS, Tayeb HO

Journal of Inflammation Research 2021, 14:4893-4900

Published Date: 22 September 2021

Original Research

Prevalence and Risk Factors Associated with the Occurrence of Autoimmune Diseases in Patients with Alopecia Areata

Chanprapaph K, Mahasaksiri T, Kositkuljorn C, Leerunyakul K, Suchonwanit P

Journal of Inflammation Research 2021, 14:4881-4891

Published Date: 22 September 2021

Case report

Acute Inflammatory Edema: A Case Report with Histopathological and Immunohistochemical Findings

Chirasuthat P, Chirasuthat S, Suchonwanit P

Journal of Inflammation Research 2021, 14:4877-4880

Published Date: 21 September 2021

Original Research

Implications for Systemic Approaches to COVID-19: Effect Sizes of Remdesivir, Tocilizumab, Melatonin, Vitamin D3, and Meditation

Castle RD, Williams MA, Bushell WC, Rindfleisch JA, Peterson CT, Marzolf J, Brouwer K, Mills PJ

Journal of Inflammation Research 2021, 14:4859-4876

Published Date: 22 September 2021

Original Research

Neutrophil Extracellular Traps Augmented Alveolar Macrophage Pyroptosis via AIM2 Inflammasome Activation in LPS-Induced ALI/ARDS

Li H, Li Y, Song C, Hu Y, Dai M, Liu B, Pan P

Journal of Inflammation Research 2021, 14:4839-4858

Published Date: 21 September 2021

Original Research

Alterations in Peripheral B Cell Subsets Correlate with the Disease Severity of Human Glaucoma

Yu L, Chen Y, Xu X, Dong Q, Xiu W, Chen Q, Wang J, He C, Ye J, Lu F

Journal of Inflammation Research 2021, 14:4827-4838

Published Date: 21 September 2021

Original Research

Potentially Functional microRNA-mRNA Regulatory Networks in Intestinal Ischemia-Reperfusion Injury: A Bioinformatics Analysis

Jiang Z, Chen S, Zhang L, Shen J, Zhong M

Journal of Inflammation Research 2021, 14:4817-4825

Published Date: 21 September 2021

Original Research

Single-Nucleotide Polymorphism LncRNA AC008392.1/rs7248320 in CARD8 is Associated with Kawasaki Disease Susceptibility in the Han Chinese Population

Guo K, Qiu L, Xu Y, Gu X, Zhang L, Lin K, Wang X, Song S, Liu Y, Niu Z, Ma S

Journal of Inflammation Research 2021, 14:4809-4816

Published Date: 21 September 2021

Original Research

Irreversible Electroporation Plus Anti-PD-1 Antibody versus Irreversible Electroporation Alone for Patients with Locally Advanced Pancreatic Cancer

He C, Sun S, Zhang Y, Li S

Journal of Inflammation Research 2021, 14:4795-4807

Published Date: 21 September 2021

Original Research

Elevated Serum Levels of Progranulin and Soluble Vascular Cell Adhesion Molecule-1 in Patients with COVID-19

Yao S, Luo N, Liu J, Zha H, Ai Y, Luo J, Shi S, Wu K

Journal of Inflammation Research 2021, 14:4785-4794

Published Date: 21 September 2021

Original Research

A Prospective Clinical Study on MGMT Protein Expression and the Effect of Gene Promoter Methylation on Sensitivity to Chemotherapeutics in Spinal Glioma

Sun P, Fan DJ, Fan T, Li X, Qi XL, Zhao XG, Gai QF

Journal of Inflammation Research 2021, 14:4777-4784

Published Date: 18 September 2021

Review

Functional Mechanism of Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Animal Models with Alzheimer’s Disease: Inhibition of Neuroinflammation

Qin C, Li Y, Wang K

Journal of Inflammation Research 2021, 14:4761-4775

Published Date: 17 September 2021

Original Research

Biotite-Calx Based Traditional Indian Medicine Sahastraputi-Abhrak-Bhasma Prophylactically Mitigates Allergic Airway Inflammation in a Mouse Model of Asthma by Amending Cytokine Responses

Balkrishna A, Solleti SK, Singh H, Singh R, Sharma N, Varshney A

Journal of Inflammation Research 2021, 14:4743-4760

Published Date: 17 September 2021

Original Research

WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin M

Henning P, Movérare-Skrtic S, Westerlund A, Souza PPC, Floriano-Marcelino T, Nilsson KH, El Shahawy M, Ohlsson C, Lerner UH

Journal of Inflammation Research 2021, 14:4723-4741

Published Date: 18 September 2021

Original Research

Astragaloside IV Protects from PM2.5-Induced Lung Injury by Regulating Autophagy via Inhibition of PI3K/Akt/mTOR Signaling in vivo and in vitro

Pei C, Wang F, Huang D, Shi S, Wang X, Wang Y, Li S, Wu Y, Wang Z

Journal of Inflammation Research 2021, 14:4707-4721

Published Date: 16 September 2021

Original Research

β-Hydroxybutyrate Mitigated Heart Failure with Preserved Ejection Fraction by Increasing Treg Cells via Nox2/GSK-3β

Liao S, Tang Y, Yue X, Gao R, Yao W, Zhou Y, Zhang H

Journal of Inflammation Research 2021, 14:4697-4706

Published Date: 16 September 2021

Original Research

Relationship Between the Eosinophil/Monocyte Ratio and Prognosis in Decompensated Heart Failure: A Retrospective Study

Chen X, Huang W, Zhao L, Li Y, Wang L, Mo F, Guo W

Journal of Inflammation Research 2021, 14:4687-4696

Published Date: 16 September 2021

Original Research

The Effects of Adoptively Transferred IL-23/IL-18-Polarized Neutrophils on Tumor and Collagen-Induced Arthritis in Mice

Chen Y, Li Y, Guo H, Zhang Z, Zhang J, Dong X, Liu Y, Zhuang Y, Zhao Y

Journal of Inflammation Research 2021, 14:4669-4686

Published Date: 16 September 2021

Original Research

Distinct Patterns of Blood Cytokines Beyond a Cytokine Storm Predict Mortality in COVID-19

Herr C, Mang S, Mozafari B, Guenther K, Speer T, Seibert M, Srikakulam SK, Beisswenger C, Ritzmann F, Keller A, Mueller R, Smola S, Eisinger D, Zemlin M, Danziger G, Volk T, Hoersch S, Krawczyk M, Lammert F, Adams T, Wagenpfeil G, Kindermann M, Marcu C, Ataya ZWD, Mittag M, Schwarzkopf K, Custodis F, Grandt D, Schaefer H, Eltges K, Lepper PM, Bals R

Journal of Inflammation Research 2021, 14:4651-4667

Published Date: 15 September 2021

Original Research

Inflammation and Insulin Resistance in a Group of Sub-Saharan African Women with Polycystic Ovary Syndrome

Chemaga Nkonpawa C, Ama Moor VJ, Tankeu AT, Momo AS, Wafeu GS, Amazia F, Nkeck JR, Manases T, Dohbit Sama J, Choukem SP

Journal of Inflammation Research 2021, 14:4643-4649

Published Date: 15 September 2021

Original Research

PLAUR as a Potential Biomarker Associated with Immune Infiltration in Bladder Urothelial Carcinoma

Liu M, Chen S, Zhang A, Zheng Q, Fu J

Journal of Inflammation Research 2021, 14:4629-4641

Published Date: 15 September 2021

Original Research

The Effect of Shaoyao Gancao Decoction on Sphincter of Oddi Dysfunction in Hypercholesterolemic Rabbits via Protecting the Enteric Nervous System–Interstitial Cells of Cajal–Smooth Muscle Cells Network

Zhu GY, Jia DD, Yang Y, Miao Y, Wang C, Wang CM

Journal of Inflammation Research 2021, 14:4615-4628

Published Date: 15 September 2021

Original Research

A Score of Low-Grade Inflammation for Predicting Stroke Recurrence in Patients with Ischemic Stroke

Wu M, Zhang X, Chen J, Zha M, Yuan K, Huang K, Xie Y, Xue J, Liu X

Journal of Inflammation Research 2021, 14:4605-4614

Published Date: 14 September 2021

Letter

Recent Insights into the Management of Inflammation in Asthma [Letter]

Urakov A, Urakova N

Journal of Inflammation Research 2021, 14:4603-4604

Published Date: 14 September 2021

Corrigendum

Clinical Significance of the HHLA2 Protein in Hepatocellular Carcinoma and the Tumor Microenvironment [Corrigendum]

Luo M, Lin Y, Liang R, Li Y, Ge L

Journal of Inflammation Research 2021, 14:4601-4602

Published Date: 14 September 2021

Original Research

Serum C1q Levels Have Prognostic Value for Sepsis and are Related to the Severity of Sepsis and Organ Damage

Li H, Chen J, Hu Y, Cai X, Tang D, Zhang P

Journal of Inflammation Research 2021, 14:4589-4600

Published Date: 10 September 2021

Original Research

Inflammation-Immunity-Nutrition Score: A Novel Prognostic Score for Patients with Resectable Colorectal Cancer

Li XY, Yao S, He YT, Ke SQ, Ma YF, Lu P, Nie SF, Wei SZ, Liang XJ, Liu L

Journal of Inflammation Research 2021, 14:4577-4588

Published Date: 10 September 2021

Erratum

Exploration of Potential Molecular Targets of Dexmedetomidine in the Intestinal Repair of Burnt Rats [Erratum]

Qin C, Jiang Y, Yu M, Bian Y, Yu Y

Journal of Inflammation Research 2021, 14:4575-4576

Published Date: 10 September 2021

Original Research

MiR-940 Serves as a Diagnostic Biomarker in Patients with Sepsis and Regulates Sepsis-Induced Inflammation and Myocardial Dysfunction

Zhang S, Wei Y, Liu J, Zhuang Y

Journal of Inflammation Research 2021, 14:4567-4574

Published Date: 9 September 2021

Original Research

LCC-09, a Novel Salicylanilide Derivative, Exerts Anti-Inflammatory Effect in Vascular Endothelial Cells

Angom RS, Zhu J, Wu ATH, Sumitra MR, Pham V, Dutta S, Wang E, Madamsetty VS, Perez-Cordero GD, Huang HS, Mukhopadhyay D, Wang Y

Journal of Inflammation Research 2021, 14:4551-4565

Published Date: 8 September 2021

Review

Managing Exacerbations in Thunderstorm Asthma: Current Insights

Chatelier J, Chan S, Tan JA, Stewart AG, Douglass JA

Journal of Inflammation Research 2021, 14:4537-4550

Published Date: 8 September 2021

Original Research

Integrative Analysis of the Roles of lncRNAs and mRNAs in Itaconate-Mediated Protection Against Liver Ischemia-Reperfusion Injury in Mice

Xu Y, Li Z, Lu S, Wang C, Ke S, Li X, Yin B, Yu H, Zhou M, Pan S, Jiang H, Ma Y

Journal of Inflammation Research 2021, 14:4519-4536

Published Date: 8 September 2021

Original Research

The Clinical Effects of Febuxostat Alone or Combined with Arthroscopic Surgery for Gout: A Single-Center Retrospective Study

Gong Z, Xia L, Xu R, Luo M, Deng H, Kang Z, Liu L, Liu Y, Zhang F, Shi J

Journal of Inflammation Research 2021, 14:4509-4517

Published Date: 7 September 2021

Research Letter

Monomeric CRP is Elevated in Patients with COPD Compared to Non-COPD Control Persons

Munuswamy R, De Brandt J, Burtin C, Derave W, Aumann J, Spruit MA, Michiels L

Journal of Inflammation Research 2021, 14:4503-4507

Published Date: 7 September 2021

Original Research

Plasma Metabolomic Profiles in Recovered COVID-19 Patients without Previous Underlying Diseases 3 Months After Discharge

Zhang S, Luo P, Xu J, Yang L, Ma P, Tan X, Chen Q, Zhou M, Song S, Xia H, Wang S, Ma Y, Yang F, Liu Y, Li Y, Ma G, Wang Z, Duan Y, Jin Y

Journal of Inflammation Research 2021, 14:4485-4501

Published Date: 7 September 2021

Review

Emerging Role of LncRNAs in Ischemic Stroke—Novel Insights into the Regulation of Inflammation

Pan Y, Jiao Q, Wei W, Zheng T, Yang X, Xin W

Journal of Inflammation Research 2021, 14:4467-4483

Published Date: 7 September 2021

Original Research

Elevated Neutrophil-to-Lymphocyte Ratio in Perioperative Periods is Suggestive of Poor Prognosis in Patients with Colorectal Cancer

Kim JH, Lee JH, Lee HS, Shin SJ, Park EJ, Cho ES, Baik SH, Lee KY, Kang J

Journal of Inflammation Research 2021, 14:4457-4466

Published Date: 7 September 2021

Original Research

Erythroferrone Expression in Anemic Rheumatoid Arthritis Patients: Is It Disordered Iron Trafficking or Disease Activity?

Youssef SR, Hassan EH, Morad CS, Elazab Elged AA, El-Gamal RA

Journal of Inflammation Research 2021, 14:4445-4455

Published Date: 7 September 2021

Original Research

The Prognostic Significance of Novel Pancreas Cancer Prognostic Index in Unresectable Locally Advanced Pancreas Cancers Treated with Definitive Concurrent Chemoradiotherapy

Topkan E, Selek U, Pehlivan B, Kucuk A, Haksoyler V, Kilic Durankus N, Sezen D, Bolukbasi Y

Journal of Inflammation Research 2021, 14:4433-4444

Published Date: 4 September 2021

Original Research

Identification and Integrated Analysis of circRNA and miRNA of Radiation-Induced Lung Injury in a Mouse Model

Li Y, Zou L, Chu L, Ye L, Ni J, Chu X, Guo T, Yang X, Zhu Z

Journal of Inflammation Research 2021, 14:4421-4431

Published Date: 2 September 2021

Original Research

Plasma Pentraxin-3 Combined with Plaque Characteristics Predict Cardiovascular Risk in ST-Segment Elevated Myocardial Infarction: An Optical Coherence Tomography Study

Wang Y, Zhao X, Zhou P, Liu C, Sheng Z, Li J, Zhou J, Chen R, Chen Y, Song L, Zhao H, Yan H

Journal of Inflammation Research 2021, 14:4409-4419

Published Date: 2 September 2021

Original Research

Inflammatory Factors as Potential Markers of Early Neurological Deterioration in Acute Ischemic Stroke Patients Receiving Endovascular Therapy – The AISRNA Study

Deng QW, Huang S, Li S, Zhai Q, Zhang Q, Wang ZJ, Chen WX, Sun H, Lu M, Zhou J

Journal of Inflammation Research 2021, 14:4399-4407

Published Date: 2 September 2021

Review

Recent Insights into the Management of Inflammation in Asthma

Rupani H, Fong WCG, Kyyaly A, Kurukulaaratchy RJ

Journal of Inflammation Research 2021, 14:4371-4397

Published Date: 2 September 2021

Original Research

The Relationship Between Serum YKL-40 Levels on Admission and Stroke-Associated Pneumonia in Patients with Acute Ischemic Stroke

Shi G, Chen W, Gong P, Wang M, Zhou J, Wang X, Guo M, Lu J, Li Y, Feng H, Fu X, Zhou R, Xue S

Journal of Inflammation Research 2021, 14:4361-4369

Published Date: 2 September 2021

Original Research

The Flavonoid Kurarinone Regulates Macrophage Functions via Aryl Hydrocarbon Receptor and Alleviates Intestinal Inflammation in Irritable Bowel Syndrome

Xu X, Dong Q, Zhong Q, Xiu W, Chen Q, Wang J, Zhou Z

Journal of Inflammation Research 2021, 14:4347-4359

Published Date: 3 September 2021

Original Research

Inhibition of MALT1 Alleviates Spinal Ischemia/Reperfusion Injury-Induced Neuroinflammation by Modulating Glial Endoplasmic Reticulum Stress in Rats

Zhang S, Yan Y, Wang Y, Sun Z, Han C, Qian X, Ren X, Feng Y, Cai J, Xia C

Journal of Inflammation Research 2021, 14:4329-4345

Published Date: 2 September 2021

Original Research

Alterations in the Plasma Proteome Induced by SARS-CoV-2 and MERS-CoV Reveal Biomarkers for Disease Outcomes for COVID-19 Patients

Alaiya A, Alshukairi A, Shinwari Z, AL-Fares M, Alotaibi J, AlOmaim W, Alsharif I, Bakheet R, Alharbi L, Allam R, Asiri A, Memish Z, Alromaih K, Al-Mozaini M

Journal of Inflammation Research 2021, 14:4313-4328

Published Date: 1 September 2021

Original Research

Overexpression of Lin28a Aggravates Psoriasis-Like Phenotype by Regulating the Proliferation and Differentiation of Keratinocytes

Jang S, Jang S, Kim SY, Ko J, Kim E, Park JY, Hyung H, Lee JH, Lim SG, Park S, Yi J, Lee HJ, Kim MO, Lee HS, Ryoo ZY

Journal of Inflammation Research 2021, 14:4299-4312

Published Date: 30 August 2021

Original Research

Increase in Blood–Brain Barrier Permeability is Modulated by Tissue Kallikrein via Activation of Bradykinin B1 and B2 Receptor-Mediated Signaling

Zhang Q, Tan J, Wan L, Chen C, Wu B, Ke X, Wu R, Ran X

Journal of Inflammation Research 2021, 14:4283-4297

Published Date: 30 August 2021

Original Research

Antibiotic Combined with Epitope-Specific Monoclonal Antibody Cocktail Protects Mice Against Bacteremia and Acute Pneumonia from Methicillin-Resistant Staphylococcus aureus Infection

Duan L, Zhang J, Chen Z, Gou Q, Xiong Q, Yuan Y, Jing H, Zhu J, Ni L, Zheng Y, Liu Z, Zhang X, Zeng H, Zou Q, Zhao Z

Journal of Inflammation Research 2021, 14:4267-4282

Published Date: 30 August 2021

Review

Insights into the Implications of Coexisting Type 2 Inflammatory Diseases

McCormick JP, Lee JT

Journal of Inflammation Research 2021, 14:4259-4266

Published Date: 30 August 2021

Original Research

Expression Pattern and Clinical Value of Key m6A RNA Modification Regulators in Abdominal Aortic Aneurysm

Li T, Wang T, Jing J, Sun L

Journal of Inflammation Research 2021, 14:4245-4258

Published Date: 29 August 2021

Original Research

Dynamic Changes of Antibodies to SARS-CoV-2 in Close Contacts

Yao J, Wang H, Yu W, Li Y, Luo Z, Wu B, Zhang W, Liu X, Lv C

Journal of Inflammation Research 2021, 14:4233-4243

Published Date: 29 August 2021

Corrigendum

Overexpression of HOXB4 Promotes Protection of Bone Marrow Mesenchymal Stem Cells Against Lipopolysaccharide-Induced Acute Lung Injury Partially Through the Activation of Wnt/β-Catenin Signaling [Corrigendum]

Lin S, Chen Q, Zhang L, Ge S, Luo Y, He W, Xu C, Zeng M

Journal of Inflammation Research 2021, 14:4229-4231

Published Date: 30 August 2021

Original Research

Clinical Significance of the HHLA2 Protein in Hepatocellular Carcinoma and the Tumor Microenvironment

Luo M, Lin Y, Liang R, Li Y, Ge L

Journal of Inflammation Research 2021, 14:4217-4228

Published Date: 28 August 2021

Original Research

Comparison of Radiation Pneumonitis in Lung Cancer Patients Treated with HT versus IMRT and Circulating Lymphocyte Subsets as Predicting Risk Factors

Zhang X, Yang D, Jiang Y, Huang L, Wang C, Tao D, Liu X, Lei Y, Wu Y, Zhou W

Journal of Inflammation Research 2021, 14:4205-4215

Published Date: 28 August 2021

Original Research

Lipocalin-2 Alleviates LPS-Induced Inflammation Through Alteration of Macrophage Properties

Du H, Liang L, Li J, Xiong Q, Yu X, Yu H

Journal of Inflammation Research 2021, 14:4189-4203

Published Date: 26 August 2021

Original Research

Clinical Significance of the Serum lncRNA NORAD Expression in Patients with Neonatal Sepsis and Its Association with miR-410-3p

Zhang H, Li L, Xu L, Zheng Y

Journal of Inflammation Research 2021, 14:4181-4188

Published Date: 26 August 2021

Original Research

Dysregulation of DPP4-CXCL12 Balance by TGF-β1/SMAD Pathway Promotes CXCR4+ Inflammatory Cell Infiltration in Keloid Scars

Chen Z, Gao Z, Xia L, Wang X, Lu L, Wu X

Journal of Inflammation Research 2021, 14:4169-4180

Published Date: 26 August 2021

Review

New Insights into the Role of NLRP3 Inflammasome in Pathogenesis and Treatment of Chronic Obstructive Pulmonary Disease

Zhang J, Xu Q, Sun W, Zhou X, Fu D, Mao L

Journal of Inflammation Research 2021, 14:4155-4168

Published Date: 26 August 2021

Original Research

Bioinformatics Analysis for Identification of Key Genes in Salivary Gland and the Potential of a Combination of Biomarkers for the Diagnosis of SS

Chen L, Lu D, Yu K, He S, Liu L, Zhang X, Feng B, Wang X

Journal of Inflammation Research 2021, 14:4143-4153

Published Date: 25 August 2021

Original Research

Effect of Vitamin D Deficiency and Supplementation in Lactation and Early Life on Allergic Airway Inflammation and the Expression of Autophagy-Related Genes in an Ovalbumin Mouse Model

Zhou Y, Xue Y, Bao A, Han L, Bao W, Xia C, Tian X, Zhang M

Journal of Inflammation Research 2021, 14:4125-4141

Published Date: 24 August 2021

Original Research

Transcriptome Analysis Reveals the Molecular Immunological Characteristics of Lesions in Patients with Halo Nevi When Compared to Stable Vitiligo, Normal Nevocytic Nevi and Cutaneous Melanoma

Pan C, Shang J, Jiang H, Shi Y, Zhang W, Xiong J, Mei Y, Long S, Ge G, Wang Z, Wu Z, Wang H, Wu A

Journal of Inflammation Research 2021, 14:4111-4124

Published Date: 24 August 2021

Original Research

Predictive Models for HCC Prognosis, Recurrence Risk, and Immune Infiltration Based on Two Exosomal Genes: MYL6B and THOC2

Zhu J, Tang B, Gao Y, Xu S, Tu J, Wang Y, Yang W, Fang S, Weng Q, Zhao Z, Xu M, Yang Y, Chen M, Lu C, Ji J

Journal of Inflammation Research 2021, 14:4089-4109

Published Date: 24 August 2021

Original Research

Nrf2 Regulates CHI3L1 to Suppress Inflammation and Improve Post-Traumatic Osteoarthritis

Song Y, Hao D, Jiang H, Huang M, Du Q, Lin Y, Liu F, Chen B

Journal of Inflammation Research 2021, 14:4079-4088

Published Date: 24 August 2021

Original Research

The Relationship Between Circulating Bone Morphogenetic Protein-4 and Inflammation Cytokines in Patients Undergoing Thoracic Surgery: A Prospective Randomized Study

Zhao X, Zhang J, Zhang W, Dai R, Xu J, Li Z, Yang L

Journal of Inflammation Research 2021, 14:4069-4077

Published Date: 21 August 2021

Original Research

Localized and Systemic Inflammatory Mediators in a Murine Acute Mastitis Model

Takashima M, Lalonde C, Olszanski LA, Zhao FQ

Journal of Inflammation Research 2021, 14:4053-4067

Published Date: 21 August 2021

Original Research

Lung Inflammatory Response to Environmental Dust Exposure in Mice Suggests a Link to Regional Respiratory Disease Risk

Burr AC, Velazquez JV, Ulu A, Kamath R, Kim SY, Bilg AK, Najera A, Sultan I, Botthoff JK, Aronson E, Nair MG, Nordgren TM

Journal of Inflammation Research 2021, 14:4035-4052

Published Date: 21 August 2021

Original Research

Nomogram Based on Lactate Dehydrogenase-to-Albumin Ratio (LAR) and Platelet-to-Lymphocyte Ratio (PLR) for Predicting Survival in Nasopharyngeal Carcinoma

Peng RR, Liang ZG, Chen KH, Li L, Qu S, Zhu XD

Journal of Inflammation Research 2021, 14:4019-4033

Published Date: 20 August 2021

Original Research

The Role of Adenosine Receptor A2A in the Regulation of Macrophage Exosomes and Vascular Endothelial Cells During Bone Healing

Wang D, Wang J, Zhou J, Zheng X

Journal of Inflammation Research 2021, 14:4001-4017

Published Date: 17 August 2021

Original Research

Human Amniotic Mesenchymal Stem Cells Inhibit aGVHD by Regulating Balance of Treg and T Effector Cells

Gao Y, Li W, Bu X, Xu Y, Cai S, Zhong JM, Du M, Sun H, Huang L, He Y, Hu X, Liu Q, Jin H, Wang Q, Ping B

Journal of Inflammation Research 2021, 14:3985-3999

Published Date: 16 August 2021

Original Research

Necroptosis Underlies Neutrophilic Inflammation Associated with the Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

Xie Y, Li M, Chen K, Zhu H, Tang M, Zhou C, Zheng Y, Wen J, Han M, Zhang J, Zhao K, Xiao H, Li H

Journal of Inflammation Research 2021, 14:3969-3983

Published Date: 16 August 2021

Original Research

The Impact of CB1 Receptor on Inflammation in Skeletal Muscle Cells

Haddad M

Journal of Inflammation Research 2021, 14:3959-3967

Published Date: 14 August 2021

Original Research

Cardiomyocyte Stim1 Deficiency Exacerbates Doxorubicin Cardiotoxicity by Magnification of Endoplasmic Reticulum Stress

Zhu J, Zhang X, Xie H, Wang Y, Zhang X, Lin Z

Journal of Inflammation Research 2021, 14:3945-3958

Published Date: 14 August 2021

Original Research

Increasing Age Affected Polymorphonuclear Neutrophils in Prognosis of Mycoplasma pneumoniae Pneumonia

Zhao Q, Zhang T, Zhu B, Bi Y, Jiang SW, Zhu Y, Zhao D, Liu F

Journal of Inflammation Research 2021, 14:3933-3943

Published Date: 14 August 2021

Original Research

Relationship Between Prognostic Nutritional Index and Mortality in Overweight or Obese Patients with Cancer: A Multicenter Observational Study

Zhang X, Li JH, Zhang Q, Li QQ, Zhang KP, Tang M, Ge YZ, Li W, Xu HX, Guo ZQ, Shi HP

Journal of Inflammation Research 2021, 14:3921-3932

Published Date: 14 August 2021

Original Research

Anti-Inflammatory Potentials of the n-Hexane Fraction of Alstonia boonei Stem Bark in Lipopolysaccharide-Induced Inflammation in Wistar Rats

Olanlokun JO, Olowofolahan AO, Bodede O, Adegbuyi AT, Prinsloo G, Steenkamp P, Olorunsogo OO

Journal of Inflammation Research 2021, 14:3905-3920

Published Date: 13 August 2021

Original Research

Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma

Liu M, Shan M, Zhang Y, Guo Z

Journal of Inflammation Research 2021, 14:3891-3904

Published Date: 12 August 2021

Original Research

Comparison of the Prognostic Value of Inflammation-Based Scores in Patients with Hepatocellular Carcinoma After Anti-PD-1 Therapy

Mei J, Sun XQ, Lin WP, Li SH, Lu LH, Zou JW, Wei W, Guo RP

Journal of Inflammation Research 2021, 14:3879-3890

Published Date: 11 August 2021

Original Research

Neuroinflammation and Microglial Activation at Rostral Ventrolateral Medulla Underpin Cadmium-Induced Cardiovascular Dysregulation in Rats

Tsai CY, Fang C, Wu JCC, Wu CJ, Dai KY, Chen SM

Journal of Inflammation Research 2021, 14:3863-3877

Published Date: 11 August 2021

Original Research

Propofol Ameliorates Exaggerated Human Neutrophil Activation in a LPS Sepsis Model

Bredthauer A, Geiger A, Gruber M, Pfaehler SM, Petermichl W, Bitzinger D, Metterlein T, Seyfried T

Journal of Inflammation Research 2021, 14:3849-3862

Published Date: 11 August 2021

Original Research

Early Elevation of Thioredoxin-1 Serum Levels Predicts 28-Day Mortality in Patients with Sepsis

Li X, Shen H, Zhou T, Cao X, Chen Y, Liang Y, Lu T, He J, Dou Z, Liu C, Tang Y, Zhu Z

Journal of Inflammation Research 2021, 14:3837-3848

Published Date: 11 August 2021

Original Research

Generation and Characterization of Torudokimab (LY3375880): A Monoclonal Antibody That Neutralizes Interleukin-33

Okragly AJ, Corwin KB, Elia M, He D, Schroeder O, Zhang Q, Shiyanova T, Bright S, Dicker SB, Chlewicki L, Truhlar SME, Davies J, Patel CN, Benschop RJ

Journal of Inflammation Research 2021, 14:3823-3835

Published Date: 11 August 2021

Original Research

Identification and Validation of a Novel Inflammatory Response-Related Gene Signature for the Prognosis of Colon Cancer

Liang Y, Wu X, Su Q, Liu Y, Xiao H

Journal of Inflammation Research 2021, 14:3809-3821

Published Date: 11 August 2021

Original Research

Symmetric Dimethylarginine is Altered in Patients After Myocardial Infarction and Predicts Adverse Outcomes

Gąsecka A, Szwed P, Jasińska K, Fidali O, Kłębukowska A, Eyileten C, Postula M, Szarpak Ł, Mazurek T, Opolski G, Filipiak KJ, Ufnal M

Journal of Inflammation Research 2021, 14:3797-3808

Published Date: 10 August 2021

Original Research

Characterization of Virus Replication, Pathogenesis, and Cytokine Responses in Syrian Hamsters Inoculated with SARS-CoV-2

Yang SJ, Wei TC, Hsu CH, Ho SN, Lai CY, Huang SF, Chen YY, Liu SJ, Yu GY, Dou HY

Journal of Inflammation Research 2021, 14:3781-3795

Published Date: 11 August 2021

Original Research

Clinical Strains of Pseudomonas aeruginosa Secrete LasB Elastase to Induce Hemorrhagic Diffuse Alveolar Damage in Mice

Zhu Y, Ge X, Xie D, Wang S, Chen F, Pan S

Journal of Inflammation Research 2021, 14:3767-3780

Published Date: 6 August 2021

Original Research

Gut Microbiota-Derived Inflammation-Related Serum Metabolites as Potential Biomarkers for Major Depressive Disorder

Bai S, Xie J, Bai H, Tian T, Zou T, Chen JJ

Journal of Inflammation Research 2021, 14:3755-3766

Published Date: 6 August 2021

Original Research

Profiling the Expression of Circulating Acute-Phase Proteins, Cytokines, and Checkpoint Proteins in Patients with Severe Trauma: A Pilot Study

Wu SC, Rau CS, Kuo PJ, Shih FY, Lin HP, Wu YC, Hsieh TM, Liu HT, Hsieh CH

Journal of Inflammation Research 2021, 14:3739-3753

Published Date: 6 August 2021

Original Research

Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells

Nkadimeng SM, Steinmann CM, Eloff JN

Journal of Inflammation Research 2021, 14:3729-3738

Published Date: 5 August 2021

Original Research

A Single-Center Retrospective Observational Study Evaluating the Favorable Predictive Factors for the Disease Control Time of Treatment with Tocilizumab in Patients of Rheumatoid Arthritis

Ishii N, Shimizu T, Ishiura Y, Amuro H, Nishizawa T, Tamaki T, Nomura S

Journal of Inflammation Research 2021, 14:3721-3728

Published Date: 5 August 2021

Review

The Promoting Effect of Traumatic Brain Injury on the Incidence and Progression of Glioma: A Review of Clinical and Experimental Research

Lan YL, Zhu Y, Chen G, Zhang J

Journal of Inflammation Research 2021, 14:3707-3720

Published Date: 4 August 2021

Original Research

LPS-Induced Inflammation Affects Midazolam Clearance in Juvenile Mice in an Age-Dependent Manner

Zheng Y, Ye PP, Zhou Y, Wu SY, Liu XT, Du B, Tang BH, Kan M, Nie AQ, Yin R, Wang M, Hao GX, Song LL, Yang XM, Huang X, Su LQ, Wang WQ, van den Anker J, Zhao W

Journal of Inflammation Research 2021, 14:3697-3706

Published Date: 3 August 2021

Original Research

miR-486-5p Serves as a Diagnostic Biomarker for Sepsis and Its Predictive Value for Clinical Outcomes

Sun B, Guo S

Journal of Inflammation Research 2021, 14:3687-3695

Published Date: 30 July 2021

Original Research

Integrating Bioinformatic Strategies with Real-World Data to Infer Distinctive Immunocyte Infiltration Landscape and Immunologically Relevant Transcriptome Fingerprints in Ossification of Ligamentum Flavum

Zhang B, Chen G, Chen X, Yang X, Fan T, Sun C, Chen Z

Journal of Inflammation Research 2021, 14:3665-3685

Published Date: 30 July 2021

Review

A Potential Role of Vitamin D on Platelet Leukocyte Aggregation and Pathological Events in Sepsis: An Updated Review

Alharbi A

Journal of Inflammation Research 2021, 14:3651-3664

Published Date: 30 July 2021

Original Research

Overexpression of HOXB4 Promotes Protection of Bone Marrow Mesenchymal Stem Cells Against Lipopolysaccharide-Induced Acute Lung Injury Partially Through the Activation of Wnt/β-Catenin Signaling

Lin S, Chen Q, Zhang L, Ge S, Luo Y, He W, Xu C, Zeng M

Journal of Inflammation Research 2021, 14:3637-3649

Published Date: 27 July 2021

Review

Mechanosensitive Piezo1 Channel Evoked-Mechanical Signals in Atherosclerosis

Shinge SAU, Zhang D, Achu Muluh T, Nie Y, Yu F

Journal of Inflammation Research 2021, 14:3621-3636

Published Date: 27 July 2021

Original Research

Associations of Single Nucleotide Polymorphisms in IL-18 Gene with Plasmodium falciparum-Associated Malaria

AlRuwaisan AU, Al-Anazi MR, Shafeai MI, Rudiny FH, Motaen AM, Bin Dajem SM, Alothaid H, Morsy K, Alkahtani S, Al-Qahtani AA

Journal of Inflammation Research 2021, 14:3587-3619

Published Date: 26 July 2021

Original Research

Effects of Photobiomodulation Therapy Combined with Static Magnetic Field in Severe COVID-19 Patients Requiring Intubation: A Pragmatic Randomized Placebo-Controlled Trial

De Marchi T, Frâncio F, Ferlito JV, Weigert R, de Oliveira C, Merlo AP, Pandini DL, Pasqual-Júnior BA, Giovanella D, Tomazoni SS, Leal-Junior EC

Journal of Inflammation Research 2021, 14:3569-3585

Published Date: 24 July 2021

Original Research

IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis

Hossain MA, Adithan A, Alam MJ, Kopalli SR, Kim B, Kang CW, Hwang KC, Kim JH

Journal of Inflammation Research 2021, 14:3555-3568

Published Date: 24 July 2021

Original Research

Identification of Key Candidate Genes Related to Inflammatory Osteolysis Associated with Vitamin E-Blended UHMWPE Debris of Orthopedic Implants by Integrated Bioinformatics Analysis and Experimental Confirmation

Liu F, Dong J, Zhou D, Zhang Q

Journal of Inflammation Research 2021, 14:3537-3554

Published Date: 26 July 2021

Original Research

Resveratrol Relieves Gouty Arthritis by Promoting Mitophagy to Inhibit Activation of NLRP3 Inflammasomes

Fan W, Chen S, Wu X, Zhu J, Li J

Journal of Inflammation Research 2021, 14:3523-3536

Published Date: 24 July 2021

Original Research

Release and Actions of Inflammatory Exosomes in Pulmonary Emphysema: Potential Therapeutic Target of Acupuncture

Zou Y, Bhat OM, Yuan X, Li G, Huang D, Guo Y, Zhou D, Li PL

Journal of Inflammation Research 2021, 14:3501-3521

Published Date: 24 July 2021

Original Research

PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles

Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J

Journal of Inflammation Research 2021, 14:3489-3500

Published Date: 22 July 2021

Original Research

Examining the Association Between Serum Leptin and Sarcopenic Obesity

Yang ZY, Chen WL

Journal of Inflammation Research 2021, 14:3481-3487

Published Date: 22 July 2021

Original Research

GARP and GARP-Treated tDC Prevented the Formation of Atherosclerotic Plaques in ApoE−/- Mice

Cai Y, Zeng Q, Liu Y, Zhu R, Yu K, Xu W, Wang Y, Ding Y, Yu J, Pan C, Peng Y, Mao Y, Cheng P, Huang L, Mao X, Zhong Y

Journal of Inflammation Research 2021, 14:3465-3479

Published Date: 22 July 2021

Original Research

The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis

Saber S, Yahya G, Gobba NA, Sharaf H, Alshaman R, Alattar A, Amin NA, El-Shedody R, Aboutouk FH, Abd El-Galeel Y, El-Hefnawy A, Shabaka D, Khalifa A, Saleh R, Osama D, El-Zoghby G, Youssef ME

Journal of Inflammation Research 2021, 14:3443-3463

Published Date: 21 July 2021

Review

Recent Insights into the Management of Behçet Syndrome

Ozguler Y, Ozdede A, Hatemi G

Journal of Inflammation Research 2021, 14:3429-3441

Published Date: 20 July 2021

Review

Immunomodulation as a Potent COVID-19 Pharmacotherapy: Past, Present and Future

Hertanto DM, Wiratama BS, Sutanto H, Wungu CDK

Journal of Inflammation Research 2021, 14:3419-3428

Published Date: 20 July 2021

Original Research

Platelet-Derived Growth Factor Regulates the Biological Behavior of Oral Mucosal Fibroblasts by Inducing Cell Autophagy and Its Mechanism

Wang J, Yang L, You J, Wen D, Yang B, Jiang C

Journal of Inflammation Research 2021, 14:3405-3417

Published Date: 17 July 2021

Original Research

Quercetin Alleviates Osteoarthritis Progression in Rats by Suppressing Inflammation and Apoptosis via Inhibition of IRAK1/NLRP3 Signaling

Li W, Wang Y, Tang Y, Lu H, Qi Y, Li G, He H, Lu F, Yang Y, Sun H

Journal of Inflammation Research 2021, 14:3393-3403

Published Date: 16 July 2021

Review

Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy

Engel T, Smith J, Alves M

Journal of Inflammation Research 2021, 14:3367-3392

Published Date: 18 July 2021

Original Research

Effectiveness of Tocilizumab with and without Dexamethasone in Patients with Severe COVID-19: A Retrospective Study

Zarębska-Michaluk D, Jaroszewicz J, Rogalska M, Martonik D, Pabjan P, Berkan-Kawińska A, Bolewska B, Oczko-Grzesik B, Kozielewicz D, Tudrujek-Zdunek M, Kowalska J, Moniuszko-Malinowska A, Kłos K, Rorat M, Leszczyński P, Piekarska A, Polańska J, Flisiak R

Journal of Inflammation Research 2021, 14:3359-3366

Published Date: 16 July 2021

Original Research

Genetic Polymorphisms in Genes Involved in the Type I Interferon System (IFIH1/MDA-5, TNFAIP3/A20, and STAT4): Association with SLE Risk in Egyptian Children and Adolescents

Zedan MM, Attia ZR, Abd El Azeem RA, Mutawi TM, El Shehawy AS, Bakr A

Journal of Inflammation Research 2021, 14:3349-3358

Published Date: 15 July 2021

Original Research

Distribution of COPD Comorbidities and Creation of Acute Exacerbation Risk Score: Results from SCICP

Ge H, Liu X, Gu W, Feng X, Zhang F, Han F, Qian Y, Jin X, Gao B, Yu L, Bao H, Zhou M, Li S, Jie Z, Wang J, Chen Z, Hang J, Zhang J, Zhu H

Journal of Inflammation Research 2021, 14:3335-3348

Published Date: 15 July 2021

Original Research

Tissue Kallikrein Exacerbating Sepsis-Induced Endothelial Hyperpermeability is Highly Predictive of Severity and Mortality in Sepsis

Ran X, Zhang Q, Li S, Yu Z, Wan L, Wu B, Wu R, Li S

Journal of Inflammation Research 2021, 14:3321-3333

Published Date: 15 July 2021

Original Research

A Cardiac Protection of Germinated Brown Rice During Cardiopulmonary Bypass Surgery and Simulated Myocardial Ischemia

Demeekul K, Sukumolanan P, Bootcha R, Panprom C, Petchdee S

Journal of Inflammation Research 2021, 14:3307-3319

Published Date: 15 July 2021

Review

The Emerging Clinical Application of m6A RNA Modification in Inflammatory Bowel Disease and Its Associated Colorectal Cancer

Xu X, Huang J, Ocansey DKW, Xia Y, Zhao Z, Xu Z, Yan Y, Zhang X, Mao F

Journal of Inflammation Research 2021, 14:3289-3306

Published Date: 15 July 2021

Original Research

Gamma Radiation Induce Inflammasome Signaling and Pyroptosis in Microvascular Endothelial Cells

Smith AO, Ju W, Adzraku SY, wenyi L, Yuting C, Qiao J, Xu K, Zeng L

Journal of Inflammation Research 2021, 14:3277-3288

Published Date: 15 July 2021

Original Research

Duzhong Fang Attenuates the POMC-Derived Neuroinflammation in Parkinsonian Mice

Li L, Fan S, Zhang W, Li D, Yang Z, Zhuang P, Han J, Guo H, Zhang Y

Journal of Inflammation Research 2021, 14:3261-3276

Published Date: 23 July 2021

Original Research

Efficacy of Methotrexate on Rat Knee Osteoarthritis Induced by Monosodium Iodoacetate

Yamanashi Y, Ohmichi M, Ohmichi Y, Ikemoto T, Arai YC, Maruyama Y, Otsuka S, Hirai S, Naito M, Deie M

Journal of Inflammation Research 2021, 14:3247-3259

Published Date: 15 July 2021

Original Research

Combining Preoperative and Postoperative Inflammatory Indicators Can Better Predict the Recurrence of Hepatocellular Carcinoma After Partial Hepatectomy

Wu M, Yang S, Feng X, Li C, Liu X, Zhang Z, Xiao Y, Liu C, Dong J

Journal of Inflammation Research 2021, 14:3231-3245

Published Date: 13 July 2021

Original Research

Mesenchymal Stem Cell-Derived Exosomes Induced by IL-1β Attenuate Urethral Stricture Through Let-7c/PAK1/NF-κB-Regulated Macrophage M2 Polarization

Chen YH, Dong RN, Hou J, Lin TT, Chen SH, Chen H, Zhu JM, Chen JY, Ke ZB, Lin F, Xue XY, Wei Y, Xu N

Journal of Inflammation Research 2021, 14:3217-3229

Published Date: 13 July 2021

Original Research

Predictive Value of C-Reactive Protein-to-Albumin Ratio for Neonatal Sepsis

Li T, Li X, Wei Y, Dong G, Yang J, Yang J, Fang P, Qi M

Journal of Inflammation Research 2021, 14:3207-3215

Published Date: 13 July 2021

Original Research

Exploration of Potential Molecular Targets of Dexmedetomidine in the Intestinal Repair of Burnt Rats

Qin C, Jiang Y, Yu M, Bian Y, Yu Y

Journal of Inflammation Research 2021, 14:3197-3206

Published Date: 13 July 2021

Original Research

Assessment of Pyroptosis-Related Indicators as Potential Biomarkers and Their Association with Severity in Patients with Liver Cirrhosis

Wang D, Zhan X, Wu R, You Y, Chen W, Duan L

Journal of Inflammation Research 2021, 14:3185-3196

Published Date: 13 July 2021

Review

Role of Goblet Cells in Intestinal Barrier and Mucosal Immunity

Yang S, Yu M

Journal of Inflammation Research 2021, 14:3171-3183

Published Date: 13 July 2021

Review

Comprehensive Mechanism, Novel Markers and Multidisciplinary Treatment of Severe Acute Pancreatitis-Associated Cardiac Injury – A Narrative Review

Luo Y, Li Z, Ge P, Guo H, Li L, Zhang G, Xu C, Chen H

Journal of Inflammation Research 2021, 14:3145-3169

Published Date: 12 July 2021

Original Research

Grape Seed Proanthocyanidin Extract Moderated Retinal Pigment Epithelium Cellular Senescence Through NAMPT/SIRT1/NLRP3 Pathway

Wan W, Zhu W, Wu Y, Long Y, Liu H, Wan W, Wan G, Yu J

Journal of Inflammation Research 2021, 14:3129-3143

Published Date: 12 July 2021

Case Series

Prevalence and Characteristics of Rheumatoid-Associated Autoantibodies in Patients with COVID-19

Xu C, Fan J, Luo Y, Zhao Z, Tang P, Yang G, Pan Y, Guo S, Liu Y, Xiong Y, Xie W, Long X

Journal of Inflammation Research 2021, 14:3123-3128

Published Date: 12 July 2021

Original Research

Methyl Diet Enhanced Sepsis-Induced Mortality Through Altering Gut Microbiota

Yu C, Zhu X, Zheng C, Luo Y, Wang F, Gao Y, Wu H, Sun X, Kong X

Journal of Inflammation Research 2021, 14:3107-3121

Published Date: 9 July 2021

Original Research

Oral Limonite Supplement Ameliorates Glucose Intolerance in Diabetic and Obese Mice

Uchida A, Yasuma T, Takeshita A, Toda M, Okano Y, Nishihama K, D'Alessandro-Gabazza CN, Fridman D'Alessandro V, Inoue C, Takagi T, Mukaiyama H, Takagi N, Shimizu K, Yano Y, Gabazza EC

Journal of Inflammation Research 2021, 14:3089-3105

Published Date: 9 July 2021

Review

Myocarditis Induced by Immune Checkpoint Inhibitors: Mechanisms and Therapeutic Prospects

Zou W, Lu J, Hao Y

Journal of Inflammation Research 2021, 14:3077-3088

Published Date: 8 July 2021

Original Research

Melatonin Attenuates Neuroinflammation by Down-Regulating NLRP3 Inflammasome via a SIRT1-Dependent Pathway in MPTP-Induced Models of Parkinson’s Disease

Zheng R, Ruan Y, Yan Y, Lin Z, Xue N, Yan Y, Tian J, Yin X, Pu J, Zhang B

Journal of Inflammation Research 2021, 14:3063-3075

Published Date: 8 July 2021

Original Research

The Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Reduces Malondialdehyde and Nitric Oxide Levels in Deep Dermal Burn Injury

Josh F, Soekamto TH, Adriani JR, Jonatan B, Mizuno H, Faruk M

Journal of Inflammation Research 2021, 14:3049-3061

Published Date: 8 July 2021

Original Research

Association of Aldehyde Dehydrogenase 2 Gene Polymorphism with Myocardial Infarction

Zhu LP, Yin WL, Peng L, Zhou XH, Zhou P, Xuan SX, Luo Y, Chen C, Cheng B, Lin JD, Liu YM, Tan FJ, Yin WG

Journal of Inflammation Research 2021, 14:3039-3047

Published Date: 7 July 2021

Original Research

Study on the Effect of Antiplatelet and Gastric Mucosal Protection of Traditional Chinese Medicine Invigorating Qi and Hemostasis

Zhang CH, Su XL, Liu YY, Lin L, Wang YC, Li XD, Zhang JZ, Wei W

Journal of Inflammation Research 2021, 14:3023-3037

Published Date: 7 July 2021

Original Research

Inverse Association Between Helicobacter pylori Infection and Unexplained Isolated Terminal Ileitis: A Retrospective Study

Lei Y, Liu X, Liu J, Zhang M, Zhou Y, Yan W, Tian D, Zhang P, Han P

Journal of Inflammation Research 2021, 14:3015-3021

Published Date: 7 July 2021

Perspectives

N-Acetylcysteine as Adjuvant Therapy for COVID-19 – A Perspective on the Current State of the Evidence

Wong KK, Lee SWH, Kua KP

Journal of Inflammation Research 2021, 14:2993-3013

Published Date: 6 July 2021

Original Research

Overexpression of Neutrophil MMP-9 and HIF-1α May Contribute to the Finger-Like Projections Formation and Histo-Pathogenesis in Nasal Inverted Papilloma

Li T, Tan KS, Tu YY, Zhao L, Liu J, Ong HH, Wang DY, Shi L

Journal of Inflammation Research 2021, 14:2979-2991

Published Date: 6 July 2021

Original Research

Fisetin Ameliorates the Inflammation and Oxidative Stress in Lipopolysaccharide-Induced Endometritis

Jiang K, Yang J, Xue G, Dai A, Wu H

Journal of Inflammation Research 2021, 14:2963-2978

Published Date: 5 July 2021

Original Research

Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease

Zhang J, Dai Y, Yang Y, Xu J

Journal of Inflammation Research 2021, 14:2955-2962

Published Date: 5 July 2021

Original Research

Systematic Metabolic Profiling of Mice with Dextran Sulfate Sodium-Induced Colitis

Xie D, Li F, Pang D, Zhao S, Zhang M, Ren Z, Geng C, Wang C, Wei N, Jiang P

Journal of Inflammation Research 2021, 14:2941-2953

Published Date: 2 July 2021

Original Research

Features for Predicting Absorbable Pulmonary Solid Nodules as Depicted on Thin-Section Computed Tomography

Lin RY, Lv FJ, Fu BJ, Li WJ, Liang ZR, Chu ZG

Journal of Inflammation Research 2021, 14:2933-2939

Published Date: 2 July 2021

Original Research

P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspirin in Treatment of Inflammatory Pain

Jiang Y, Ye F, Du Y, Zong Y, Tang Z

Journal of Inflammation Research 2021, 14:2913-2931

Published Date: 2 July 2021

Original Research

Cadherin-11 Deficiency Attenuates Ang-II-Induced Atrial Fibrosis and Susceptibility to Atrial Fibrillation

Cao W, Song S, Fang G, Li Y, Wang Y, Wang QS

Journal of Inflammation Research 2021, 14:2897-2911

Published Date: 2 July 2021

Original Research

Increased Sphingosine-1-Phosphate Serum Concentrations in Subjects with Periodontitis: A Matter of Inflammation

Moritz E, Jedlitschky G, Negnal J, Tzvetkov MV, Daum G, Dörr M, Felix SB, Völzke H, Nauck M, Schwedhelm E, Meisel P, Kocher T, Rauch BH, Holtfreter B

Journal of Inflammation Research 2021, 14:2883-2896

Published Date: 30 June 2021

Original Research

Study on the Clinical Significance of ACE2 and Its Age-Related Expression

Gu J, Yin J, Zhang M, Li J, Wu Y, Chen J, Miao H

Journal of Inflammation Research 2021, 14:2873-2882

Published Date: 30 June 2021

Original Research

The lncRNA ANRIL Gene rs2151280 GG Genotype is Associated with Increased Susceptibility to Recurrent Miscarriage in a Southern Chinese Population

Che D, Fang Z, Mai H, Xu Y, Fu L, Zhou H, Zhang L, Pi L, Gu X

Journal of Inflammation Research 2021, 14:2865-2872

Published Date: 30 June 2021

Original Research

Regulation of IFN-Is by MEF2D Promotes Inflammatory Homeostasis in Microglia

Lu F, Wang R, Xia L, Nie T, Gao F, Yang S, Huang L, Shao K, Liu J, Yang Q

Journal of Inflammation Research 2021, 14:2851-2863

Published Date: 29 June 2021

Original Research

Acute P38-Mediated Enhancement of P2X3 Receptor Currents by TNF-α in Rat Dorsal Root Ganglion Neurons

Jin Y, Wei S, Liu TT, Qiu CY, Hu WP

Journal of Inflammation Research 2021, 14:2841-2850

Published Date: 29 June 2021

Original Research

The Association Between Inflammatory and Oxidative Stress Biomarkers and Plasma Metabolites in a Longitudinal Study of Healthy Male Welders

Gao S, Quick C, Guasch-Ferre M, Zhuo Z, Hutchinson JM, Su L, Hu F, Lin X, Christiani D

Journal of Inflammation Research 2021, 14:2825-2839

Published Date: 29 June 2021

Original Research

Upregulation of COX-2 and PGE2 Induced by TNF-α Mediated Through TNFR1/MitoROS/PKCα/P38 MAPK, JNK1/2/FoxO1 Cascade in Human Cardiac Fibroblasts

Yang CM, Yang CC, Hsiao LD, Yu CY, Tseng HC, Hsu CK, Situmorang JH

Journal of Inflammation Research 2021, 14:2807-2824

Published Date: 28 June 2021

Original Research

Phenotypic Variations of Mild-to-Moderate Obstructive Pulmonary Diseases According to Airway Inflammation and Clinical Features

Proboszcz M, Goryca K, Nejman-Gryz P, Przybyłowski T, Górska K, Krenke R, Paplińska-Goryca M

Journal of Inflammation Research 2021, 14:2793-2806

Published Date: 28 June 2021

Original Research

The Potential Protective Effect of Mesencephalic Astrocyte-Derived Neurotrophic Factor on Post-Operative Delirium via Inhibiting Inflammation and Microglia Activation

Liu J, Shen Q, Zhang H, Xiao X, lv C, Chu Y, Shen Y, Wang D, Shen Q

Journal of Inflammation Research 2021, 14:2781-2791

Published Date: 28 June 2021

Original Research

Induction of IL-25 Expression in Human Nasal Polyp Epithelium by Influenza Virus Infection is Abated by Interferon-Alpha Pretreatment

Hong H, Tan KS, Yan Y, Chen F, Ong HH, Oo Y, Liu J, Ong YK, Thong M, Sugrue R, Chow VT, Wang DY

Journal of Inflammation Research 2021, 14:2769-2780

Published Date: 28 June 2021

Original Research

Hydrogen Sulfide Contributes to Uterine Quiescence Through Inhibition of NLRP3 Inflammasome Activation by Suppressing the TLR4/NF-κB Signalling Pathway

Chen Z, Zhang M, Zhao Y, Xu W, Xiang F, Li X, Zhang T, Wu R, Kang X

Journal of Inflammation Research 2021, 14:2753-2768

Published Date: 25 June 2021

Original Research

Solitary Pulmonary Inflammatory Nodule: CT Features and Pathological Findings

Xiao YD, Lv FJ, Li WJ, Fu BJ, Lin RY, Chu ZG

Journal of Inflammation Research 2021, 14:2741-2751

Published Date: 25 June 2021

Original Research

A Novel Radiomics Nomogram for the Prediction of Secondary Loss of Response to Infliximab in Crohn’s Disease

Chen Y, Li H, Feng J, Suo S, Feng Q, Shen J

Journal of Inflammation Research 2021, 14:2731-2740

Published Date: 24 June 2021

Original Research

The Association Among Serum Growth Differentiation Factor 15 Level and Suicidal Ideation is Dependent on Testosterone Deficiency in Depressive Patients

Peng R, Li D, Mei SQ, Li Y

Journal of Inflammation Research 2021, 14:2723-2730

Published Date: 24 June 2021

Original Research

Spermidine Inhibits Joints Inflammation and Macrophage Activation in Mice with Collagen-Induced Arthritis

Yuan H, Wu SX, Zhou YF, Peng F

Journal of Inflammation Research 2021, 14:2713-2721

Published Date: 24 June 2021

Original Research

Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies

Gül-Klein S, Hegermann H, Röhle R, Schmelzle M, Tacke F, Schöning W, Öllinger R, Dziodzio T, Maier P, Plewe JM, Horst D, Sauer IM, Pratschke J, Lachmann N, Eurich D

Journal of Inflammation Research 2021, 14:2697-2712

Published Date: 23 June 2021

Original Research

PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function

Jiang M, Xue Y, Li J, Rao K, Yan S, Li H, Chen X, Li R, Liu D

Journal of Inflammation Research 2021, 14:2681-2696

Published Date: 25 June 2021

Original Research

Transcriptome-Wide Analysis to Identify the Inflammatory Role of lncRNA Neat1 in Experimental Ischemic Stroke

Jin F, Ou W, Wei B, Fan H, Wei C, Fang D, Li G, Liu W, Liu J, Jin L, He X, Duan C

Journal of Inflammation Research 2021, 14:2667-2680

Published Date: 22 June 2021

Review

Pyroptosis: A New Regulating Mechanism in Cardiovascular Disease

Ji N, Qi Z, Wang Y, Yang X, Yan Z, Li M, Ge Q, Zhang J

Journal of Inflammation Research 2021, 14:2647-2666

Published Date: 22 June 2021

Original Research

Treatment Effect of Mammary Duct Exploration Combined with Focal Resection on Granulomatous Lobular Mastitis

Zuo X, Shi X, Gao X, Lai R, Liu P, Zhao Z

Journal of Inflammation Research 2021, 14:2641-2646

Published Date: 21 June 2021

Original Research

FNDC1 Polymorphism (rs3003174 C > T) Increased the Incidence of Coronary Artery Aneurysm in Patients with Kawasaki Disease in a Southern Chinese Population

Lin K, Zhang L, Wang Y, Li J, Xu Y, Che D, Mai H, Yu H, Fu L, Wei B, Jiang Z, Pi L, Gu X

Journal of Inflammation Research 2021, 14:2633-2640

Published Date: 21 June 2021

Original Research

Gut Microbiota Dysbiosis Correlates with Abnormal Immune Response in Moderate COVID-19 Patients with Fever

Zhou Y, Shi X, Fu W, Xiang F, He X, Yang B, Wang X, Ma WL

Journal of Inflammation Research 2021, 14:2619-2631

Published Date: 17 June 2021

Original Research

Molecular Examination of Differentially Expressed Genes in the Brains of Experimental Autoimmune Encephalomyelitis Mice Post Herceptin Treatment

Al-Ani M, Elemam NM, Hachim IY, Raju TK, Muhammad JS, Hachim MY, Bendardaf R, Maghazachi AA

Journal of Inflammation Research 2021, 14:2601-2617

Published Date: 17 June 2021

Original Research

Genistein Attenuates Isoflurane-Induced Neuroinflammation by Inhibiting TLR4-Mediated Microglial-Polarization in vivo and in vitro

Jiang T, Xu S, Shen Y, Xu Y, Li Y

Journal of Inflammation Research 2021, 14:2587-2600

Published Date: 17 June 2021

Commentary

LRRK2-NFATc2 Pathway Associated with Neuroinflammation May Be a Potential Therapeutic Target for Parkinson’s Disease

Wang Y, Zhang X, Chen F, Chen L, Wang J, Xie J

Journal of Inflammation Research 2021, 14:2583-2586

Published Date: 16 June 2021

Original Research

Sodium Bituminosulfonate Used to Treat Rosacea Modulates Generation of Inflammatory Mediators by Primary Human Neutrophils

Schiffmann S, Gunne S, Henke M, Ulshöfer T, Steinhilber D, Sethmann A, Parnham MJ

Journal of Inflammation Research 2021, 14:2569-2582

Published Date: 16 June 2021

Clinical Trial Report

Efficacy and Safety of First-Generation EGFR-TKIs Combined with Chemotherapy for Treatment-Naïve Advanced Non-Small-Cell Lung Cancer Patients Harboring Sensitive EGFR Mutations: A Single-Center, Open-Label, Single-Arm, Phase II Clinical Trial

Lin J, Li M, Chen S, Weng L, He Z

Journal of Inflammation Research 2021, 14:2557-2567

Published Date: 16 June 2021

Review

Rheumatoid Arthritis Relapse and Remission – Advancing Our Predictive Capability Using Modern Imaging

Terslev L, Ostergaard M

Journal of Inflammation Research 2021, 14:2547-2555

Published Date: 16 June 2021

Review

Impact of Adjunctive Diode Laser Application to Non-Surgical Periodontal Therapy on Clinical, Microbiological and Immunological Outcomes in Management of Chronic Periodontitis: A Systematic Review of Human Randomized Controlled Clinical Trials

Pawelczyk-Madalińska M, Benedicenti S, Sălăgean T, Bordea IR, Hanna R

Journal of Inflammation Research 2021, 14:2515-2545

Published Date: 15 June 2021

Original Research

TRAP1 Shows Clinical Significance in the Early Diagnosis of Small Cell Lung Cancer

Li X, Li X, Chen S, Wu Y, Liu Y, Hu T, Huang J, Yu J, Pei Z, Zeng T, Tan L

Journal of Inflammation Research 2021, 14:2507-2514

Published Date: 14 June 2021

Original Research

Longitudinal Antibody Dynamics Against Structural Proteins of SARS-CoV-2 in Three COVID-19 Patients Shows Concurrent Development of IgA, IgM, and IgG

Jamiruddin MR, Haq MA, Tomizawa K, Kobatake E, Mie M, Ahmed S, Khandker SS, Ali T, Jahan N, Oishee MJ, Khondoker MU, Sil BK, Haque M, Adnan N

Journal of Inflammation Research 2021, 14:2497-2506

Published Date: 14 June 2021

Original Research

Prognostic Value of the Preoperative Lymphocyte-C-Reactive Protein Ratio in Hepatocellular Carcinoma Patients Treated with Curative Intent: A Large-Scale Multicentre Study

Zhang YF, Lu LH, Zhong C, Chen MS, Guo RP, Wang L

Journal of Inflammation Research 2021, 14:2483-2495

Published Date: 10 June 2021

Original Research

High Inflammatory Tendency Induced by Malignant Stimulation Through Imbalance of CD28 and CTLA-4/PD-1 Contributes to Dopamine Neuron Injury

Dong L, Zheng YM, Luo XG, He ZY

Journal of Inflammation Research 2021, 14:2471-2482

Published Date: 10 June 2021

Original Research

Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?

Nangole FW, Ouyang K, Anzala O, Ogengo J, Agak GW

Journal of Inflammation Research 2021, 14:2465-2470

Published Date: 10 June 2021

Original Research

LncRNA NEAT1 Promote Inflammatory Responses in Coronary Slow Flow Through Regulating miR-148b-3p/ICAM-1 Axis

Zhu Q, Zhao C, Wang Y, Li X, Xue Y, Ma C

Journal of Inflammation Research 2021, 14:2445-2463

Published Date: 9 June 2021

Original Research

Occupational Cement Dust Exposure and Inflammatory Nemesis: Bangladesh Relevance

Ahmad R, Akhter QS, Haque M

Journal of Inflammation Research 2021, 14:2425-2444

Published Date: 9 June 2021

Original Research

Protective Role of microRNA-200a in Diabetic Retinopathy Through Downregulation of PDLIM1

Wan W, Long Y, Jin X, Li Q, Wan W, Liu H, Zhu Y

Journal of Inflammation Research 2021, 14:2411-2424

Published Date: 4 June 2021

Original Research

The Correlation Between Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio with Hepatic Echinococcosis

E Weijian, Wang Z, Pang MQ, Lu Y, Fan H

Journal of Inflammation Research 2021, 14:2403-2409

Published Date: 3 June 2021

Original Research

Zc3h12d, a Novel of Hypomethylated and Immune-Related for Prognostic Marker of Lung Adenocarcinoma

Yang B, Ji LL, Xu HL, Li XP, Zhou HG, Xiao T, Li XH, Gao ZY, Li JZ, Zhang WD, Wang GS, Li MJ

Journal of Inflammation Research 2021, 14:2389-2401

Published Date: 15 June 2021

Original Research

Multi-Organ Transcriptome Dynamics in a Mouse Model of Cecal Ligation and Puncture-Induced Polymicrobial Sepsis

Rumienczyk I, Kulecka M, Ostrowski J, Mar D, Bomsztyk K, Standage SW, Mikula M

Journal of Inflammation Research 2021, 14:2377-2388

Published Date: 3 June 2021

Original Research

A Novel NGF Receptor Agonist B355252 Ameliorates Neuronal Loss and Inflammatory Responses in a Rat Model of Cerebral Ischemia

Wang HK, Chen JS, Hsu CY, Su YT, Sung TC, Liang CL, Kwan AL, Wu CC

Journal of Inflammation Research 2021, 14:2363-2376

Published Date: 1 June 2021

Original Research

Identification of an Alveolar Macrophage-Related Core Gene Set in Acute Respiratory Distress Syndrome

Zhao C, Mo J, Zheng X, Wu Z, Li Q, Feng J, Luo J, Lu J, Zhang J

Journal of Inflammation Research 2021, 14:2353-2361

Published Date: 1 June 2021

Original Research

A Synergy Between Endotoxin and (1→3)-Beta-D-Glucan Enhanced Neutrophil Extracellular Traps in Candida Administered Dextran Sulfate Solution Induced Colitis in FcGRIIB-/- Lupus Mice, an Impact of Intestinal Fungi in Lupus

Saithong S, Saisorn W, Visitchanakun P, Sae-khow K, Chiewchengchol D, Leelahavanichkul A

Journal of Inflammation Research 2021, 14:2333-2352

Published Date: 1 June 2021

Original Research

Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a

Yao J, Liu X, Sun Y, Dong X, Liu L, Gu H

Journal of Inflammation Research 2021, 14:2317-2331

Published Date: 1 June 2021

Original Research

Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice

Huang C, Cai J, Jin S, Lin Q, Fang Q, Nan K, Han Y, Ge W, Liu Y, Tao Y, Cao H, Li J

Journal of Inflammation Research 2021, 14:2301-2315

Published Date: 31 May 2021

Original Research

Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation

Li N, Xiong R, He R, Liu B, Wang B, Geng Q

Journal of Inflammation Research 2021, 14:2289-2300

Published Date: 31 May 2021

Original Research

Empagliflozin Alleviates Atherosclerosis Progression by Inhibiting Inflammation and Sympathetic Activity in a Normoglycemic Mouse Model

Liu Y, Wu M, Xu B, Kang L

Journal of Inflammation Research 2021, 14:2277-2287

Published Date: 31 May 2021

Review

Obesity-Related Inflammation and Endothelial Dysfunction in COVID-19: Impact on Disease Severity

De Lorenzo A, Estato V, Castro-Faria-Neto HC, Tibirica E

Journal of Inflammation Research 2021, 14:2267-2276

Published Date: 27 May 2021

Original Research

Melatonin Inhibits Migration and Invasion in LPS-Stimulated and -Unstimulated Prostate Cancer Cells Through Blocking Multiple EMT-Relative Pathways

Tian QX, Zhang ZH, Ye QL, Xu S, Hong Q, Xing WY, Chen L, Yu DX, Xu DX, Xie DD

Journal of Inflammation Research 2021, 14:2253-2265

Published Date: 25 May 2021

Original Research

Downregulation of Renal MRPs Transporters in Acute Lymphoblastic Leukemia Mediated by the IL-6/STAT3/PXR Signaling Pathway

Zhou Y, Nie AQ, Chen S, Wang MM, Yin R, Tang BH, Wu YE, Yang F, Du B, Shi HY, Yang XM, Hao GX, Guo XL, Han QJ, Zheng Y, Zhao W

Journal of Inflammation Research 2021, 14:2239-2252

Published Date: 25 May 2021

Original Research

Prognostic and Predictive Value of Circulating Inflammation Signature in Non-Metastatic Nasopharyngeal Carcinoma: Potential Role for Individualized Induction Chemotherapy

Lv SH, Li WZ, Liang H, Liu GY, Xia WX, Xiang YQ

Journal of Inflammation Research 2021, 14:2225-2237

Published Date: 25 May 2021

Original Research

Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo

Chen Y, Chen Y, Jiang X, Shi M, Yang Z, Chen Z, Hua X, Chen J, Wang Y

Journal of Inflammation Research 2021, 14:2207-2223

Published Date: 25 May 2021

Review

Role of Pyroptosis in Diabetes and Its Therapeutic Implications

Al Mamun A, Wu Y, Nasrin F, Akter A, Taniya MA, Munir F, Jia C, Xiao J

Journal of Inflammation Research 2021, 14:2187-2206

Published Date: 24 May 2021

Original Research

Syk-Targeted, a New 3-Arylbenzofuran Derivative EAPP-2 Blocks Airway Inflammation of Asthma–COPD Overlap in vivo and in vitro

Li S, Hui Y, Yuan J, Zhang Z, Li X, Fang N, Lin M, Hou Q

Journal of Inflammation Research 2021, 14:2173-2185

Published Date: 24 May 2021

Original Research

Exogenous Plant gma-miR-159a, Identified by miRNA Library Functional Screening, Ameliorated Hepatic Stellate Cell Activation and Inflammation via Inhibiting GSK-3β-Mediated Pathways

Yu WY, Cai W, Ying HZ, Zhang WY, Zhang HH, Yu CH

Journal of Inflammation Research 2021, 14:2157-2172

Published Date: 24 May 2021

Original Research

A Gender-Dependent Molecular Switch of Inflammation via MyD88/Estrogen Receptor-Alpha Interaction

El Sabeh R, Bonnet M, Le Corf K, Lang K, Kfoury A, Badran B, Hussein N, Virard F, Treilleux I, Le Romancer M, Lebecque S, Manie S, Coste I, Renno T

Journal of Inflammation Research 2021, 14:2149-2156

Published Date: 21 May 2021

Original Research

Preclinical Characterization of the Selective JAK1 Inhibitor LW402 for Treatment of Rheumatoid Arthritis

Zhang N, Zhang C, Zeng Z, Zhang J, Du S, Bao C, Wang Z

Journal of Inflammation Research 2021, 14:2133-2147

Published Date: 21 May 2021

Original Research

In vivo and in vitro Evaluation of Cytokine Expression Profiles During Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection

Mubarak A, Alrfaei B, Aljurayyan A, Alqafil MM, Farrag MA, Hamed ME, Alosaimi B, Almajhdi F, Alturaiki W

Journal of Inflammation Research 2021, 14:2121-2131

Published Date: 21 May 2021

Hypothesis

A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies

Kulke M, Nagel F, Schulig L, Geist N, Gabor M, Mayerle J, Lerch MM, Link A, Delcea M

Journal of Inflammation Research 2021, 14:2111-2119

Published Date: 21 May 2021

Review

Fat-Soluble Vitamins and the Current Global Pandemic of COVID-19: Evidence-Based Efficacy from Literature Review

Samad N, Dutta S, Sodunke TE, Fairuz A, Sapkota A, Miftah ZF, Jahan I, Sharma P, Abubakar AR, Rowaiye AB, Oli AN, Charan J, Islam S, Haque M

Journal of Inflammation Research 2021, 14:2091-2110

Published Date: 21 May 2021

Review

Role of Ferroptosis in Lung Diseases

Xu W, Deng H, Hu S, Zhang Y, Zheng L, Liu M, Chen Y, Wei J, Yang H, Lv X

Journal of Inflammation Research 2021, 14:2079-2090

Published Date: 20 May 2021

Original Research

Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion

Lin X, Zhan J, Jiang J, Ren Y

Journal of Inflammation Research 2021, 14:2061-2078

Published Date: 20 May 2021

Original Research

The ACE2-Ang-(1‑7)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Mediated NF-кb and MAPK Pathways

Pan H, Huang W, Wang Z, Ren F, Luo L, Zhou J, Tian M, Tang L

Journal of Inflammation Research 2021, 14:2045-2060

Published Date: 20 May 2021

Original Research

MiRNA-29c-3p Promotes Intestinal Inflammation via Targeting Leukemia Inhibitory Factor in Ulcerative Colitis

Guo J, Zhang R, Zhao Y, Wang J

Journal of Inflammation Research 2021, 14:2031-2043

Published Date: 18 May 2021

Original Research

Association Between Interleukin-12 and Sarcopenia

Chen YY, Kao TW, Chiu YL, Peng TC, Yang HF, Chen WL

Journal of Inflammation Research 2021, 14:2019-2029

Published Date: 18 May 2021

Original Research

Orexin-A Attenuates Inflammatory Responses in Lipopolysaccharide-Induced Neural Stem Cells by Regulating NF-KB and Phosphorylation of MAPK/P38/Erk Pathways

Ye W, Yan Y, Tang Y, Dong X, Chen G, Kang J, Huang L, Xiong Q, Feng Z

Journal of Inflammation Research 2021, 14:2007-2017

Published Date: 18 May 2021

Original Research

Prognostic Significance of Tumor-Associated Macrophages in Chondroblastoma and Their Association with Response to Adjuvant Radiotherapy

Zheng BW, Yang ML, Huang W, Zheng BY, Zhang TL, Li J, Lv GH, Yan YG, Zou MX

Journal of Inflammation Research 2021, 14:1991-2005

Published Date: 17 May 2021

Original Research

Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages

Wang R, Song W, Xie C, Zhong W, Xu H, Zhou Q, Deng Y, Hong Y, Li X, Fang M

Journal of Inflammation Research 2021, 14:1973-1989

Published Date: 17 May 2021

Original Research

Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice

Li L, Yang L, Yang F, Zhao XL, Xue SJ, Gong FH

Journal of Inflammation Research 2021, 14:1959-1971

Published Date: 17 May 2021

Original Research

Lentivirus-Mediated Overexpression or Silencing of Aquaporin 1 Affects the Proliferation, Migration and Invasion of TNF-α-Stimulated Rheumatoid Arthritis Fibroblast-Like Synoviocytes by Wnt/β-Catenin Signaling Pathway

Zhou MY, Cai L, Feng XW, Mu YR, Meng B, Liu FY, Li R

Journal of Inflammation Research 2021, 14:1945-1957

Published Date: 14 May 2021

Original Research

Application of Artificial Intelligence Modeling Technology Based on Multi-Omics in Noninvasive Diagnosis of Inflammatory Bowel Disease

Huang Q, Zhang X, Hu Z

Journal of Inflammation Research 2021, 14:1933-1943

Published Date: 14 May 2021

Review

Effect of Biologics on Cardiovascular Inflammation: Mechanistic Insights and Risk Reduction

Fragoulis GE, Soulaidopoulos S, Sfikakis PP, Dimitroulas T, Kitas GD

Journal of Inflammation Research 2021, 14:1915-1931

Published Date: 14 May 2021

Original Research

Punicalagin Inhibited Inflammation and Migration of Fibroblast-Like Synoviocytes Through NF-κB Pathway in the Experimental Study of Rheumatoid Arthritis

Huang M, Wu K, Zeng S, Liu W, Cui T, Chen Z, Lin L, Chen D, Ouyang H

Journal of Inflammation Research 2021, 14:1901-1913

Published Date: 12 May 2021

Original Research

Risk of Non-Alcoholic Fatty Liver Disease in Xanthelasma Palpebrarum

Chen HW, Lin JC, Wu YH, Chiu YL

Journal of Inflammation Research 2021, 14:1891-1899

Published Date: 12 May 2021

Original Research

The 4G/5G Polymorphism of Plasminogen Activator Inhibitor Type 1 is a Predictor of Moderate-to-Severe Thyroid Eye Disease

Katko M, Galgoczi E, Erdei A, Gazdag A, Berta E, Bodor M, Seres I, Hircsu I, Badics A, Ujhelyi B, Sira L, Bhattoa HP, Nagy EV

Journal of Inflammation Research 2021, 14:1883-1890

Published Date: 12 May 2021

Original Research

MCTR1 Intervention Reverses Experimental Lung Fibrosis in Mice

Pan J, Li X, Wang X, Yang L, Chen H, Su N, Wu C, Hao Y, Jin S, Li H

Journal of Inflammation Research 2021, 14:1873-1881

Published Date: 11 May 2021

Original Research

An Inflammation-Index Signature Predicts Prognosis of Patients with Intrahepatic Cholangiocarcinoma After Curative Resection

He C, Zhao C, Zhang Y, Chen C, Lin X

Journal of Inflammation Research 2021, 14:1859-1872

Published Date: 11 May 2021

Original Research

microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3

Yang QB, Li LQ, Zhang QB, He YL, Mi QS, Zhou JG

Journal of Inflammation Research 2021, 14:1845-1858

Published Date: 11 May 2021

Review

PARP Inhibitors: An Innovative Approach to the Treatment of Inflammation and Metabolic Disorders in Sepsis

Wasyluk W, Zwolak A

Journal of Inflammation Research 2021, 14:1827-1844

Published Date: 6 May 2021

Original Research

Changes of Lipopolysaccharide-Induced Acute Kidney and Liver Injuries in Rats Based on Metabolomics Analysis

Gao H, Yang T, Chen X, Song Y

Journal of Inflammation Research 2021, 14:1807-1825

Published Date: 6 May 2021

Original Research

Dual Activity of Ginsenoside Rb1 in Hypertrophic Cardiomyocytes and Activated Macrophages: Implications for the Therapeutic Intervention of Cardiac Hypertrophy

Wang S, Cui Y, Xiong M, Li M, Wang P, Cui J, Du X, Chen Y, Zhang T

Journal of Inflammation Research 2021, 14:1789-1806

Published Date: 5 May 2021

Original Research

Investigation of Wound Healing and Anti-Inflammatory Activities of Solvent Fractions of 80% Methanol Leaf Extract of Achyranthes aspera L. (Amaranthaceae) in Rats

Mengie T, Mequanente S, Nigussie D, Legesse B, Makonnen E

Journal of Inflammation Research 2021, 14:1775-1787

Published Date: 5 May 2021

Original Research

Lycopus lucidus Turcz Exerts Neuroprotective Effects Against H2O2-Induced Neuroinflammation by Inhibiting NLRP3 Inflammasome Activation in Cortical Neurons

Kim H, Hong JY, Jeon WJ, Lee J, Baek SH, Ha IH

Journal of Inflammation Research 2021, 14:1759-1773

Published Date: 5 May 2021

Original Research

The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study

Rizk NM, Fadel A, AlShammari W, Younes N, Bashah M

Journal of Inflammation Research 2021, 14:1743-1757

Published Date: 5 May 2021

Original Research

Inhibition of Long Non-Coding RNA KCNQ1OT1 Attenuates Neuroinflammation and Neuronal Apoptosis Through Regulating NLRP3 Expression via Sponging miR-30e-3p

Song A, Yang Y, He H, Sun J, Chang Q, Xue Q

Journal of Inflammation Research 2021, 14:1731-1742

Published Date: 5 May 2021

Original Research

Activation of GSK3 Prevents Termination of TNF-Induced Signaling

Welz B, Bikker R, Hoffmeister L, Diekmann M, Christmann M, Brand K, Huber R

Journal of Inflammation Research 2021, 14:1717-1730

Published Date: 6 May 2021

Review

Recent Progress in the Diagnosis and Precise Nanocarrier-Mediated Therapy of Inflammatory Bowel Disease

Wang L, Yu M, Yang H

Journal of Inflammation Research 2021, 14:1701-1716

Published Date: 29 April 2021

Original Research

Identification of Circulating Biomarkers and Construction of a Prognostic Signature for Survival Prediction in Locally Advanced Pancreatic Cancer After Irreversible Electroporation

He C, Sun S, Zhang Y, Li S

Journal of Inflammation Research 2021, 14:1689-1699

Published Date: 28 April 2021

Original Research

Factors Associated with the Expression of ACE2 in Human Lung Tissue: Pathological Evidence from Patients with Normal FEV1 and FEV1/FVC

Bao W, Zhang X, Jin Y, Hao H, Yang F, Yin D, Chen X, Xue Y, Han L, Zhang M

Journal of Inflammation Research 2021, 14:1677-1687

Published Date: 28 April 2021

Original Research

Ddb1-Cullin4-Associated-Factor 1 in Macrophages Restricts the Staphylococcus aureus-Induced Osteomyelitis

Zong Y, Shan H, Yin F, Ma X, Jiang C, Wang N, Zhou L, Lin Y, Zhou Z, Yu X

Journal of Inflammation Research 2021, 14:1667-1676

Published Date: 28 April 2021

Case report

Extremity Gangrene Caused by HBV-Related Cryoglobulinemia Vasculitis in a Patient with Diabetes – A Case Report

Gao Y, Chen D, Li Y, Chen H, Ran X

Journal of Inflammation Research 2021, 14:1661-1666

Published Date: 28 April 2021

Original Research

Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways

Jin F, Geng F, Xu D, Li Y, Li T, Yang X, Liu S, Zhang H, Wei Z, Li S, Gao X, Cai W, Mao N, Yi X, Liu H, Sun Y, Yang F, Xu H

Journal of Inflammation Research 2021, 14:1647-1660

Published Date: 27 April 2021

Original Research

An Indole-2-Carboxamide Derivative, LG4, Alleviates Diabetic Kidney Disease Through Inhibiting MAPK-Mediated Inflammatory Responses

Qian J, Yin S, Ye L, Wang Z, Shu S, Mou Z, Xu M, Chattipakorn N, Liu Z, Liang G

Journal of Inflammation Research 2021, 14:1633-1645

Published Date: 27 April 2021

Original Research

Chemokine Receptor 2 (CXCR2) Gene Polymorphisms and Their Association with the Risk of Developing Peri-Implantitis in Chinese Han Population

Qi Y, Li C, Du Y, Lin J, Li N, Yu Y

Journal of Inflammation Research 2021, 14:1625-1631

Published Date: 23 April 2021

Original Research

Comprehensive Identification of Bridge Genes to Explain the Progression from Chronic Hepatitis B Virus Infection to Hepatocellular Carcinoma

Nong W, Ma L, Lan B, Liu N, Yang H, Lao X, Deng Q, Huang Z

Journal of Inflammation Research 2021, 14:1613-1624

Published Date: 21 April 2021

Original Research

Undetected Jawbone Marrow Defects as Inflammatory and Degenerative Signaling Pathways: Chemokine RANTES/CCL5 as a Possible Link Between the Jawbone and Systemic Interactions?

Lechner J, Schmidt M, von Baehr V, Schick F

Journal of Inflammation Research 2021, 14:1603-1612

Published Date: 21 April 2021

Original Research

Models Based on Dynamic Clinicopathological Indices for Predicting Prognosis During the Perioperative Period for Patients with Colorectal Cancer

Ma Y, Lu P, Liang X, Wei S

Journal of Inflammation Research 2021, 14:1591-1601

Published Date: 21 April 2021

Review

Inflammasome as an Effective Platform for Fibrosis Therapy

Chen TT, Xiao F, Li N, Shan S, Qi M, Wang ZY, Zhang SN, Wei W, Sun WY

Journal of Inflammation Research 2021, 14:1575-1590

Published Date: 20 April 2021

Original Research

Silenced SNHG1 Inhibited Epithelial-Mesenchymal Transition and Inflammatory Response of ARPE-19 Cells Induced by High Glucose

Yang J, Yang K, Meng X, Liu P, Fu Y, Wang Y

Journal of Inflammation Research 2021, 14:1563-1573

Published Date: 20 April 2021

Original Research

HMGB1/TLR4 Signaling Affects Regulatory T Cells in Acute Lung Injury

Zhou M, Zhang Y, Tang R, Liu H, Du M, Gao Z, Ji Z, Fang H

Journal of Inflammation Research 2021, 14:1551-1561

Published Date: 19 April 2021

Original Research

Rosuvastatin Enhances Alveolar Fluid Clearance in Lipopolysaccharide-Induced Acute Lung Injury by Activating the Expression of Sodium Channel and Na,K-ATPase via the PI3K/AKT/Nedd4-2 Pathway

Xu HR, Yang Q, Xiang SY, Zhang PH, Ye Y, Chen Y, Xu KW, Ren XY, Mei HX, Shen CX, Ma HY, Smith FG, Jin SW, Wang Q

Journal of Inflammation Research 2021, 14:1537-1549

Published Date: 16 April 2021

Original Research

Methanolic Fenugreek Seed Extract Induces p53-Dependent Mitotic Catastrophe in Breast Cancer Cells, Leading to Apoptosis

Alrumaihi FA, Khan MA, Allemailem KS, Alsahli MA, Almatroudi A, Younus H, Alsuhaibani SA, Algahtani M, Khan A

Journal of Inflammation Research 2021, 14:1511-1535

Published Date: 16 April 2021

Review

Attenuating the Effects of Novel COVID-19 (SARS-CoV-2) Infection-Induced Cytokine Storm and the Implications

Rowaiye AB, Okpalefe OA, Onuh Adejoke O, Ogidigo JO, Hannah Oladipo O, Ogu AC, Oli AN, Olofinase S, Onyekwere O, Rabiu Abubakar A, Jahan D, Islam S, Dutta S, Haque M

Journal of Inflammation Research 2021, 14:1487-1510

Published Date: 16 April 2021

Original Research

Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure

Wang Y, Li X, Chen Q, Jiao F, Shi C, Pei M, Wang L, Gong Z

Journal of Inflammation Research 2021, 14:1473-1485

Published Date: 15 April 2021

Original Research

Integrated Systems Pharmacology and Surface Plasmon Resonance Approaches to Reveal the Synergistic Effect of Multiple Components of Gu-Ben-Ke-Chuan Decoction on Chronic Bronchitis

Luo Z, Yu G, Wang W, Sun R, Zhang B, Wang J, Liu J, Gao S, Wang P, Shi Y

Journal of Inflammation Research 2021, 14:1455-1471

Published Date: 15 April 2021

Original Research

Study of the Expression of Inflammatory Factors IL-4, IL-6, IL-10, and IL-17 in Liver Failure Complicated by Coagulation Dysfunction and Sepsis

Li L, Chen L, Lin F, Mu J, Wang D, Zhang W, Mi L, Qin Y, Zhou Y

Journal of Inflammation Research 2021, 14:1447-1453

Published Date: 15 April 2021

Original Research

Diet-Related Inflammation is Associated with Major Depressive Disorder in Bahraini Adults: Results of a Case-Control Study Using the Dietary Inflammatory Index

Chen W, Faris AIE, Bragazzi NL, AlGahtani HMS, Saif Z, Jahrami A, Shivappa N, Hebert JR, Jahrami H

Journal of Inflammation Research 2021, 14:1437-1445

Published Date: 15 April 2021

Original Research

Research on Correlation Between Psychological Factors, Mast Cells, and PAR-2 Signal Pathway in Irritable Bowel syndrome

Chao G, Wang Z, Zhang S

Journal of Inflammation Research 2021, 14:1427-1436

Published Date: 14 April 2021

Original Research

Acute Phase Responses Vary Between Children of HbAS and HbAA Genotypes During Plasmodium falciparum Infection

Tetteh M, Addai-Mensah O, Siedu Z, Kyei-Baafour E, Lamptey H, Williams J, Kupeh E, Egbi G, Kwayie AB, Abbam G, Afrifah DA, Debrah AY, Ofori MF

Journal of Inflammation Research 2021, 14:1415-1426

Published Date: 14 April 2021

Original Research

Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study

Hu X, Li R, Sun M, Kong Y, Zhu H, Wang F, Wan Q

Journal of Inflammation Research 2021, 14:1403-1414

Published Date: 13 April 2021

Original Research

Hydrogen (H2) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway

Lu H, Wang W, Kang X, Lin Z, Pan J, Cheng S, Zhang J

Journal of Inflammation Research 2021, 14:1387-1402

Published Date: 13 April 2021

Original Research

LXA4 Inhibits Lipopolysaccharide-Induced Inflammatory Cell Accumulation by Resident Macrophages in Mice

Mei HX, Ye Y, Xu HR, Xiang SY, Yang Q, Ma HY, Jin SW, Wang Q

Journal of Inflammation Research 2021, 14:1375-1385

Published Date: 12 April 2021

Original Research

Changes in Plasma Growth Differentiation Factor-15 After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients: A Prospective Study

Salman A, Shaaban HED, Salman M, M Seif El Nasr S, Soliman A, Salem A, Tag El-Din M, Mikhail HMS, El Domiaty H, Abd Allah N, GabAllah GMK, Youssef A

Journal of Inflammation Research 2021, 14:1365-1373

Published Date: 12 April 2021

Original Research

The Pulsatile Modification Improves Hemodynamics and Attenuates Inflammatory Responses in Extracorporeal Membrane Oxygenation

Li G, Zeng J, Liu Z, Zhang Y, Fan X

Journal of Inflammation Research 2021, 14:1357-1364

Published Date: 12 April 2021

Original Research

Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson’s Disease Mouse Model

Jing L, Hou L, Zhang D, Li S, Ruan Z, Zhang X, Hong JS, Wang Q

Journal of Inflammation Research 2021, 14:1341-1356

Published Date: 9 April 2021

Original Research

Decreased T Cell Levels in Critically Ill Coronavirus Patients: Single-Center, Prospective and Observational Study

Xu J, Liu Z, Liu H, Luo Y, Kang K, Li X, Yang W, Fei D, Wang C, Yu K

Journal of Inflammation Research 2021, 14:1331-1340

Published Date: 9 April 2021

Original Research

RETRACTED ARTICLE: Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway

Naeem K, Tariq Al Kury L, Nasar F, Alattar A, Alshaman R, Shah FA, Khan AU, Li S

Journal of Inflammation Research 2021, 14:1313-1329

Published Date: 8 April 2021

Original Research

Lack of Macrophage Migration Inhibitory Factor Reduces Susceptibility to Ventricular Arrhythmias During the Acute Phase of Myocardial Infarction

Lyu J, Huang J, Wu J, Yu T, Wei X, Lei Q

Journal of Inflammation Research 2021, 14:1297-1311

Published Date: 7 April 2021

Original Research

SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury

Wang D, Cao H, Wang X, Wang J, Wang M, Zhang J, Wang L

Journal of Inflammation Research 2021, 14:1283-1296

Published Date: 7 April 2021

Original Research

Hypothermia Protects Mice Against Ischemic Stroke by Modulating Macrophage Polarization Through Upregulation of Interferon Regulatory Factor-4

Yu X, Feng Y, Liu R, Chen Q

Journal of Inflammation Research 2021, 14:1271-1281

Published Date: 7 April 2021

Original Research

Interferon-λ3 Exacerbates the Inflammatory Response to Microbial Ligands: Implications for SARS-CoV-2 Pathogenesis

Read SA, Gloss BS, Liddle C, George J, Ahlenstiel G

Journal of Inflammation Research 2021, 14:1257-1270

Published Date: 1 April 2021

Original Research

Tripterygium wilfordii Polyglycoside Ameliorated TNBS-Induced Colitis in Rats via Regulating Th17/Treg Balance in Intestinal Mucosa

Zhang C, Ju J, Wu X, Yang J, Yang Q, Liu C, Chen L, Sun X

Journal of Inflammation Research 2021, 14:1243-1255

Published Date: 1 April 2021

Original Research

White Blood Cell Count as a Predictor of Incident Type 2 Diabetes Mellitus Among Non-Obese Adults: A Longitudinal 10-Year Analysis of the Korean Genome and Epidemiology Study

Park JM, Lee HS, Park JY, Jung DH, Lee JW

Journal of Inflammation Research 2021, 14:1235-1242

Published Date: 1 April 2021

Original Research

Dexmedetomidine Attenuates Ischemia/Reperfusion-Induced Myocardial Inflammation and Apoptosis Through Inhibiting Endoplasmic Reticulum Stress Signaling

Yang Y, Wang H, Song N, Jiang Y, Zhang J, Meng X, Feng X, Liu H, Peng K, Ji F

Journal of Inflammation Research 2021, 14:1217-1233

Published Date: 31 March 2021

Original Research

Association of Early Inflammation with Age and Asymptomatic Disease in COVID-19

Xie C, Li Q, Li L, Peng X, Ling Z, Xiao B, Feng J, Chen Z, Chang D, Xie L, Dela Cruz CS, Sharma L

Journal of Inflammation Research 2021, 14:1207-1216

Published Date: 30 March 2021

Original Research

Anti-Inflammatory and Antiviral Osmotic Polymeric Film to Treat Covid-19 Early-Stage Infection

Shrivastava R, Shrivastava R, Johansen B, Allain T

Journal of Inflammation Research 2021, 14:1195-1206

Published Date: 30 March 2021

Review

Current Status of Functional Studies on Circular RNAs in Rheumatoid Arthritis and Their Potential Role as Diagnostic Biomarkers

Xu Y, Chen F

Journal of Inflammation Research 2021, 14:1185-1193

Published Date: 30 March 2021

Original Research

Anti-TWEAK Antibody Alleviates Renal Interstitial Fibrosis by Increasing PGC-1α Expression in Lupus Nephritis

Xue L, Zhang Y, Xu J, Lu W, Wang Q, Fu J, Liu Z

Journal of Inflammation Research 2021, 14:1173-1184

Published Date: 26 March 2021

Original Research

Helping Roles of Artificial Intelligence (AI) in the Screening and Evaluation of COVID-19 Based on the CT Images

Xie H, Li Q, Hu PF, Zhu SH, Zhang JF, Zhou HD, Zhou HB

Journal of Inflammation Research 2021, 14:1165-1172

Published Date: 26 March 2021

Review

Activation and Inhibition of the NLRP3 Inflammasome by RNA Viruses

Choudhury SM, Ma X, Abdullah SW, Zheng H

Journal of Inflammation Research 2021, 14:1145-1163

Published Date: 26 March 2021

Original Research

MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats

Feng X, Hu J, Zhan F, Luo D, Hua F, Xu G

Journal of Inflammation Research 2021, 14:1125-1143

Published Date: 26 March 2021

Original Research

Longitudinal Chest CT Features in Severe/Critical COVID-19 Cases and the Predictive Value of the Initial CT for Mortality

Li H, Luo S, Zhang Y, Xiao X, Liu H

Journal of Inflammation Research 2021, 14:1111-1124

Published Date: 25 March 2021

Original Research

Restraint Stress in Hypertensive Rats Activates the Intestinal Macrophages and Reduces Intestinal Barrier Accompanied by Intestinal Flora Dysbiosis

Wang T, Gao L, Yang Z, Wang F, Guo Y, Wang B, Hua R, Shang H, Xu J

Journal of Inflammation Research 2021, 14:1085-1110

Published Date: 25 March 2021

Original Research

FUT7 Promotes the Epithelial–Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma

Liu M, Zheng Q, Chen S, Liu J, Li S

Journal of Inflammation Research 2021, 14:1069-1084

Published Date: 25 March 2021

Original Research

The Serum from Patients with Secondary Frozen Shoulder Following Rotator Cuff Repair Induces Shoulder Capsule Fibrosis and Promotes Macrophage Polarization and Fibroblast Activation

Sun Y, Lin J, Luo Z, Zhang Y, Chen J

Journal of Inflammation Research 2021, 14:1055-1068

Published Date: 23 March 2021

Original Research

Complement Profiles in Patients with Amyotrophic Lateral Sclerosis: A Prospective Observational Cohort Study

Kjældgaard AL, Pilely K, Olsen KS, Øberg Lauritsen A, Wørlich Pedersen S, Svenstrup K, Karlsborg M, Thagesen H, Blaabjerg M, Theódórsdóttir Á, Gundtoft Elmo E, Torvin Møller A, Pedersen NA, Kirkegaard N, Møller K, Garred P

Journal of Inflammation Research 2021, 14:1043-1053

Published Date: 23 March 2021

Review

Metalloproteinases in Inflammatory Bowel Diseases

Marônek M, Marafini I, Gardlík R, Link R, Troncone E, Monteleone G

Journal of Inflammation Research 2021, 14:1029-1041

Published Date: 23 March 2021

Original Research

BT2 Suppresses Human Monocytic-Endothelial Cell Adhesion, Bone Erosion and Inflammation

Yeh MC, Wu BJ, Li Y, Elahy M, Prado-Lourenco L, Sockler J, Lau H, Day RO, Khachigian LM

Journal of Inflammation Research 2021, 14:1019-1028

Published Date: 23 March 2021

Original Research

CTRP9 Enhances Efferocytosis in Macrophages via MAPK/Drp1-Mediated Mitochondrial Fission and AdipoR1-Induced Immunometabolism

Song CX, Chen JY, Li N, Guo Y

Journal of Inflammation Research 2021, 14:1007-1017

Published Date: 23 March 2021

Original Research

The Influence of an Occult Infection on the Outcome of Autologous Bone Grafting During Surgical Bone Reconstruction: A Large Single-Center Case-Control Study

Tanner MC, Heller RA, Grimm A, Zimmermann S, Pilz M, Jurytko L, Miska M, Helbig L, Schmidmaier G, Haubruck P

Journal of Inflammation Research 2021, 14:995-1005

Published Date: 22 March 2021

Original Research

Mechanisms of Adiponectin in Regulation of Proinflammatory Cytokine Production and Migration in Macrophages

Jin X, Wang Y

Journal of Inflammation Research 2021, 14:981-993

Published Date: 22 March 2021

Clinical Trial Report

Evaluation of Adjunctive Photobiomodulation (PBMT) for COVID-19 Pneumonia via Clinical Status and Pulmonary Severity Indices in a Preliminary Trial

Vetrici MA, Mokmeli S, Bohm AR, Monici M, Sigman SA

Journal of Inflammation Research 2021, 14:965-979

Published Date: 19 March 2021

Original Research

Poor Clearance of Free Hemoglobin Due to Lower Active Haptoglobin Availability is Associated with Osteoarthritis Inflammation

Sarkar A, Monu, Kumar V, Malhotra R, Pandit H, Jones E, Ponchel F, Biswas S

Journal of Inflammation Research 2021, 14:949-964

Published Date: 18 March 2021

Hypothesis

The Binary Classification of Protein Kinases

Elkoshi Z

Journal of Inflammation Research 2021, 14:929-947

Published Date: 18 March 2021

Original Research

Stable Cells with NF-κB-ZsGreen Fused Genes Created by TALEN Editing and Homology Directed Repair for Screening Anti-inflammation Drugs

Zhang S, Luo T, Wang J

Journal of Inflammation Research 2021, 14:917-928

Published Date: 17 March 2021

Original Research

Adiponectin, but Not TGF-β1, CTGF, IL-6 or TNF-α, May Be a Potential Anti-Inflammation and Anti-Fibrosis Factor in Keloid

Luo L, Li J, Wu Y, Qiao J, Fang H

Journal of Inflammation Research 2021, 14:907-916

Published Date: 16 March 2021

Original Research

Associations Between Tenascin-C and Testosterone Deficiency in Men with Major Depressive Disorder: A Cross-Sectional Retrospective Study

Peng R, Li Y

Journal of Inflammation Research 2021, 14:897-905

Published Date: 16 March 2021

Original Research

Altered Monocyte Subsets in Kawasaki Disease Revealed by Single-cell RNA-Sequencing

Geng Z, Tao Y, Zheng F, Wu L, Wang Y, Wang Y, Sun Y, Fu S, Wang W, Xie C, Zhang Y, Gong F

Journal of Inflammation Research 2021, 14:885-896

Published Date: 16 March 2021

Original Research

Coronil, a Tri-Herbal Formulation, Attenuates Spike-Protein-Mediated SARS-CoV-2 Viral Entry into Human Alveolar Epithelial Cells and Pro-Inflammatory Cytokines Production by Inhibiting Spike Protein-ACE-2 Interaction

Balkrishna A, Haldar S, Singh H, Roy P, Varshney A

Journal of Inflammation Research 2021, 14:869-884

Published Date: 16 March 2021

Original Research

Efficacy of a Standardized Turmeric Extract Comprised of 70% Bisdemothoxy-Curcumin (REVERC3) Against LPS-Induced Inflammation in RAW264.7 Cells and Carrageenan-Induced Paw Edema

Gouthamchandra K, Sudeep HV, Chandrappa S, Raj A, Naveen P, Shyamaprasad K

Journal of Inflammation Research 2021, 14:859-868

Published Date: 12 March 2021

Original Research

Estrogen Protects Articular Cartilage by Downregulating ASIC1a in Rheumatoid Arthritis

Hang X, Zhang Z, Niu R, Wang C, Yao J, Xu Y, Tao J, Li L, Chen F

Journal of Inflammation Research 2021, 14:843-858

Published Date: 12 March 2021

Original Research

Screening of Key Genes of Sepsis and Septic Shock Using Bioinformatics Analysis

Zeng X, Feng J, Yang Y, Zhao R, Yu Q, Qin H, Wei L, Ji P, Li H, Wu Z, Zhang J

Journal of Inflammation Research 2021, 14:829-841

Published Date: 11 March 2021

Original Research

A Scoring System Based on Nutritional and Inflammatory Parameters to Predict the Efficacy of First-Line Chemotherapy and Survival Outcomes for De Novo Metastatic Nasopharyngeal Carcinoma

Li WZ, Hua X, Lv SH, Liang H, Liu GY, Lu N, Bei WX, Xia WX, Xiang YQ

Journal of Inflammation Research 2021, 14:817-828

Published Date: 10 March 2021

Original Research

Sodium Propionate Enhances Nrf2-Mediated Protective Defense Against Oxidative Stress and Inflammation in Lipopolysaccharide-Induced Neonatal Mice

Chen D, Gao Z, Wang Y, Wan B, Liu G, Chen J, Wu Y, Zhou Q, Jiang S, Yu R, Pang Q

Journal of Inflammation Research 2021, 14:803-816

Published Date: 10 March 2021

Original Research

Integrated Bioinformatic Analysis of SARS-CoV-2 Infection Related Genes ACE2, BSG and TMPRSS2 in Aerodigestive Cancers

He C, Hua X, Sun S, Li S, Wang J, Huang X

Journal of Inflammation Research 2021, 14:791-802

Published Date: 10 March 2021

Original Research

Deoxycholic Acid and Lithocholic Acid Alleviate Liver Injury and Inflammation in Mice with Klebsiella pneumoniae-Induced Liver Abscess and Bacteremia

Zheng Y, Yue C, Zhang H, Chen H, Liu Y, Li J

Journal of Inflammation Research 2021, 14:777-789

Published Date: 9 March 2021

Original Research

Endothelin-1/Endothelin Receptor Type A-Angiopoietins/Tie-2 Pathway in Regulating the Cross Talk Between Glomerular Endothelial Cells and Podocytes in Trichloroethylene-Induced Renal Immune Injury

Xie H, Wang H, Wu Q, Peng J, Huang H, Wang Y, Huang M, Jiang W, Yang Y, Zhang X, Zhang J, Zhu Q

Journal of Inflammation Research 2021, 14:761-776

Published Date: 9 March 2021

Original Research

Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo

Wang H, Jiang Z, Pang Z, Qi G, Hua B, Yan Z, Yuan H

Journal of Inflammation Research 2021, 14:745-760

Published Date: 9 March 2021

Original Research

Possible Role of Regulatory B Cells in Different Behçet’s Disease Phenotypes and Therapies: First Report from Egypt

Hetta HF, Mohamed AAA, Zahran AM, Mahran SA, Sayed MM, Saleh MGA, Abdelazeem K, Batiha GES, Al-Rejaie S, Waheed Y, Muhammad K, Hassanien MM

Journal of Inflammation Research 2021, 14:737-744

Published Date: 8 March 2021

Original Research

KCa3.1 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease

Zheng F, Tao Y, Liu J, Geng Z, Wang Y, Wang Y, Fu S, Wang W, Xie C, Zhang Y, Gong F

Journal of Inflammation Research 2021, 14:719-735

Published Date: 5 March 2021

Original Research

Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway

Shen R, Yin P, Yao H, Chen L, Chang X, Li H, Hou X

Journal of Inflammation Research 2021, 14:711-718

Published Date: 5 March 2021

Original Research

Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats

Sucedaram Y, Johns EJ, Husain R, Abdul Sattar M, H Abdulla M, Nelli G, Rahim NS, Khalilpourfarshbafi M, Abdullah NA

Journal of Inflammation Research 2021, 14:689-710

Published Date: 5 March 2021

Review

Chinese Herbs and Repurposing Old Drugs as Therapeutic Agents in the Regulation of Oxidative Stress and Inflammation in Pulmonary Diseases

Yang CC, Yang CM

Journal of Inflammation Research 2021, 14:657-687

Published Date: 4 March 2021

Original Research

Susceptibility-Related Cytokine Panel for Prediction of Polygonum multiflorum-Induced Hepatotoxicity in Humans

Tu C, Niu M, Wei AW, Tang JF, Zhang L, Jing J, Xiao XH, Wang JB

Journal of Inflammation Research 2021, 14:645-655

Published Date: 4 March 2021

Original Research

C-Reactive Protein Mediates the Effect of Serum Progesterone on Obesity for Men and Postmenopausal Women in Henan Rural Cohort Study

Nie L, Wei D, Liu P, Zhang L, Fan K, Song Y, Wang M, Wang L, Xu Q, Wang J, Liu X, Li L, Mao Z, Huang H, Wang C, Huo W

Journal of Inflammation Research 2021, 14:633-644

Published Date: 4 March 2021

Original Research

Identification of Potential Early Diagnostic Biomarkers of Sepsis

Li Z, Huang B, Yi W, Wang F, Wei S, Yan H, Qin P, Zou D, Wei R, Chen N

Journal of Inflammation Research 2021, 14:621-631

Published Date: 3 March 2021

Hypothesis

The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways

Cao X, Li Y, Shi J, Tang H

Journal of Inflammation Research 2021, 14:611-619

Published Date: 26 February 2021

Original Research

High Concentrations of Etanercept Reduce Human Islet Function and Integrity

Brandhorst D, Brandhorst H, Acreman S, Abraham A, Johnson PRV

Journal of Inflammation Research 2021, 14:599-610

Published Date: 26 February 2021

Original Research

Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages

Hu TY, Zhang H, Chen YY, Jiao WH, Fan JT, Liu ZQ, Lin HW, Cheng BH

Journal of Inflammation Research 2021, 14:587-597

Published Date: 25 February 2021

Original Research

Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A

Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J

Journal of Inflammation Research 2021, 14:575-586

Published Date: 25 February 2021

Original Research

Markers of Chronic Inflammation in Overweight and Obese Individuals and the Role of Gender: A Cross-Sectional Study of a Large Cohort

Cohen E, Margalit I, Shochat T, Goldberg E, Krause I

Journal of Inflammation Research 2021, 14:567-573

Published Date: 25 February 2021

Original Research

Crm1-Dependent Nuclear Export of Bach1 is Involved in the Protective Effect of Hyperoside on Oxidative Damage in Hepatocytes and CCl4-induced Acute Liver Injury

Cai Y, Li B, Peng D, Wang X, Li P, Huang M, Xing H, Chen J

Journal of Inflammation Research 2021, 14:551-565

Published Date: 25 February 2021

Review

The Implications of Zinc Therapy in Combating the COVID-19 Global Pandemic

Samad N, Sodunke TE, Abubakar AR, Jahan I, Sharma P, Islam S, Dutta S, Haque M

Journal of Inflammation Research 2021, 14:527-550

Published Date: 26 February 2021

Original Research

Plasma Neutrophil-to-Lymphocyte Ratio on the Third Day Postburn is Associated with 90-Day Mortality Among Patients with Burns Over 30% of Total Body Surface Area in Two Chinese Burns Centers

Qiu L, Jin X, Wang JJ, Tang XD, Fang X, Li SJ, Wang F, Chen XL

Journal of Inflammation Research 2021, 14:519-526

Published Date: 24 February 2021

Original Research

AST-120 Improves Cardiac Dysfunction in Acute Kidney Injury Mice via Suppression of Apoptosis and Proinflammatory NF-κB/ICAM-1 Signaling

Shen WC, Chou YH, Shi LS, Chen ZW, Tu HJ, Lin XY, Wang GJ

Journal of Inflammation Research 2021, 14:505-518

Published Date: 24 February 2021

Original Research

Potential Biomarkers for Diagnosing Major Depressive Disorder Patients with Suicidal Ideation

Bai S, Fang L, Xie J, Bai H, Wang W, Chen J

Journal of Inflammation Research 2021, 14:495-503

Published Date: 22 February 2021

Original Research

Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells/Macrophage Co-Culture System

Meng YF, Pu Q, Dai SY, Ma Q, Li X, Zhu W

Journal of Inflammation Research 2021, 14:479-493

Published Date: 22 February 2021

Original Research

Regulation of Pancreatic Fibrosis by Acinar Cell-Derived Exosomal miR-130a-3p via Targeting of Stellate Cell PPAR-γ

Wang Q, Wang H, Jing Q, Yang Y, Xue D, Hao C, Zhang W

Journal of Inflammation Research 2021, 14:461-477

Published Date: 24 February 2021

Original Research

Therapeutic Potentials of Colocasia affinis Leaf Extract for the Alleviation of Streptozotocin-Induced Diabetes and Diabetic Complications: In vivo and in silico-Based Studies

Shill MC, Bepari AK, Khan M, Tasneem Z, Ahmed T, Hasan MA, Alam MJ, Hossain M, Rahman MA, Sharker SM, Shahriar M, Rahman GMS, Reza HM

Journal of Inflammation Research 2021, 14:443-459

Published Date: 19 February 2021

Original Research

Distinctive Under-Expression Profile of Inflammatory and Redox Genes in the Blood of Elderly Patients with Cardiovascular Disease

Milanesi E, Manda G, Dobre M, Codrici E, Neagoe IV, Popescu BO, Bajenaru OA, Spiru L, Tudose C, Prada GI, Davidescu EI, Piñol-Ripoll G, Cuadrado A

Journal of Inflammation Research 2021, 14:429-442

Published Date: 18 February 2021

Original Research

Comprehensive Analysis of LncRNA-mRNA Expression Profiles and the ceRNA Network Associated with Pyroptosis in LPS-Induced Acute Lung Injury

Luo D, Liu F, Zhang J, Shao Q, Tao W, Xiao R, Dai W, Ding C, Qian K

Journal of Inflammation Research 2021, 14:413-428

Published Date: 17 February 2021

Original Research

Securidaca inappendiculata-Derived Xanthones Protected Joints from Degradation in Male Rats with Collagen-Induced Arthritis by Regulating PPAR-γ Signaling

Zuo J, Tao MQ, Wu XY, Jiang TT, Olatunji OJ, Dong J, Han J, Ji CL

Journal of Inflammation Research 2021, 14:395-411

Published Date: 16 February 2021

Erratum

Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity [Erratum]

Chen Y, Cheng J, Zhang Y, Chen JDZ, Seralu FM

Journal of Inflammation Research 2021, 14:393-394

Published Date: 16 February 2021

Review

Inflammatory Markers Related to Innate and Adaptive Immunity in Atherosclerosis: Implications for Disease Prediction and Prospective Therapeutics

Hong LZ, Xue Q, Shao H

Journal of Inflammation Research 2021, 14:379-392

Published Date: 16 February 2021

Original Research

Adenosine A2A Receptor Agonist Polydeoxyribonucleotide Alleviates Interstitial Cystitis-Induced Voiding Dysfunction by Suppressing Inflammation and Apoptosis in Rats

Ko IG, Jin JJ, Hwang L, Kim SH, Kim CJ, Won KY, Na YG, Kim KH, Kim SJ

Journal of Inflammation Research 2021, 14:367-378

Published Date: 15 February 2021

Original Research

Exposure to Maternal Immune Activation Causes Congenital Unfolded Protein Response Defects and Increases the Susceptibility to Postnatal Inflammatory Stimulation in Offspring

Shimizu Y, Tsukada T, Sakata-Haga H, Sakai D, Shoji H, Saikawa Y, Hatta T

Journal of Inflammation Research 2021, 14:355-365

Published Date: 12 February 2021

Original Research

Iridin Prevented Against Lipopolysaccharide-Induced Inflammatory Responses of Macrophages via Inactivation of PKM2-Mediated Glycolytic Pathways

Ying ZH, Li HM, Yu WY, Yu CH

Journal of Inflammation Research 2021, 14:341-354

Published Date: 5 February 2021

Original Research

Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity

Chen Y, Cheng J, Zhang Y, Chen JDZ, Seralu FM

Journal of Inflammation Research 2021, 14:325-339

Published Date: 5 February 2021

Original Research

Association of a High Neutrophil-to-Lymphocyte Ratio with Hyperdense Artery Sign and Unfavorable Short-Term Outcomes in Patients with Acute Ischemic Stroke

Lin SK, Chen PY, Chen GC, Hsu PJ, Hsiao CL, Yang FY, Liu CY, Tsou A

Journal of Inflammation Research 2021, 14:313-324

Published Date: 5 February 2021

Original Research

Aryl Hydrocarbon Receptor is Essential in the Control of Lung Club Cell Homeostasis

Liu KY, Wang LT, Wang HC, Wang SN, Tseng LW, Chai CY, Chiou SS, Huang SK, Hsu SH

Journal of Inflammation Research 2021, 14:299-311

Published Date: 5 February 2021

Original Research

Analysis of the Effect of Proton-Pump Inhibitors on the Course of COVID-19

Zhang XY, Li T, Wu H, Ling Y, Qian ZP, Chen L

Journal of Inflammation Research 2021, 14:287-298

Published Date: 5 February 2021

Original Research

CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets

Liu F, Wu H

Journal of Inflammation Research 2021, 14:267-285

Published Date: 5 February 2021

Corrigendum

Association of Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study [Corrigendum]

Yousef AA, Mohamed FY, Boraey NF, Akeel NE, Soliman AA, Waked NM, Hashem MIA, Shehata H, Fahmy DS, Ismael A, Ibrahim LM, Ibrahim MAM, Salem HF, Yousry SM, Osman SF, Fouad RA, Enan ET, Attia MA, Afify MR, Zeidan NMS, Nashat M

Journal of Inflammation Research 2021, 14:265-266

Published Date: 4 February 2021

Review