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Journal of Inflammation Research
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Archive: Volume 14, 2021
Deoxycholic Acid and Lithocholic Acid Alleviate Liver Injury and Inflammation in Mice with Klebsiella pneumoniae-Induced Liver Abscess and Bacteremia
Zheng Y, Yue C, Zhang H, Chen H, Liu Y, Li J
Journal of Inflammation Research 2021, 14:777-789
Published Date: 9 March 2021
Endothelin-1/Endothelin Receptor Type A-Angiopoietins/Tie-2 Pathway in Regulating the Cross Talk Between Glomerular Endothelial Cells and Podocytes in Trichloroethylene-Induced Renal Immune Injury
Xie H, Wang H, Wu Q, Peng J, Huang H, Wang Y, Huang M, Jiang W, Yang Y, Zhang X, Zhang J, Zhu Q
Journal of Inflammation Research 2021, 14:761-776
Published Date: 9 March 2021
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo
Wang H, Jiang Z, Pang Z, Qi G, Hua B, Yan Z, Yuan H
Journal of Inflammation Research 2021, 14:745-760
Published Date: 9 March 2021
Possible Role of Regulatory B Cells in Different Behçet’s Disease Phenotypes and Therapies: First Report from Egypt
Hetta HF, Mohamed AAA, Zahran AM, Mahran SA, Sayed MM, Saleh MGA, Abdelazeem K, Batiha GES, Al-Rejaie S, Waheed Y, Muhammad K, Hassanien MM
Journal of Inflammation Research 2021, 14:737-744
Published Date: 8 March 2021
KCa3.1 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease
Zheng F, Tao Y, Liu J, Geng Z, Wang Y, Wang Y, Fu S, Wang W, Xie C, Zhang Y, Gong F
Journal of Inflammation Research 2021, 14:719-735
Published Date: 5 March 2021
Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway
Shen R, Yin P, Yao H, Chen L, Chang X, Li H, Hou X
Journal of Inflammation Research 2021, 14:711-718
Published Date: 5 March 2021
Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats
Sucedaram Y, Johns EJ, Husain R, Abdul Sattar M, H Abdulla M, Nelli G, Rahim NS, Khalilpourfarshbafi M, Abdullah NA
Journal of Inflammation Research 2021, 14:689-710
Published Date: 5 March 2021
Chinese Herbs and Repurposing Old Drugs as Therapeutic Agents in the Regulation of Oxidative Stress and Inflammation in Pulmonary Diseases
Yang CC, Yang CM
Journal of Inflammation Research 2021, 14:657-687
Published Date: 4 March 2021
Susceptibility-Related Cytokine Panel for Prediction of Polygonum multiflorum-Induced Hepatotoxicity in Humans
Tu C, Niu M, Wei AW, Tang JF, Zhang L, Jing J, Xiao XH, Wang JB
Journal of Inflammation Research 2021, 14:645-655
Published Date: 4 March 2021
C-Reactive Protein Mediates the Effect of Serum Progesterone on Obesity for Men and Postmenopausal Women in Henan Rural Cohort Study
Nie L, Wei D, Liu P, Zhang L, Fan K, Song Y, Wang M, Wang L, Xu Q, Wang J, Liu X, Li L, Mao Z, Huang H, Wang C, Huo W
Journal of Inflammation Research 2021, 14:633-644
Published Date: 4 March 2021
Identification of Potential Early Diagnostic Biomarkers of Sepsis
Li Z, Huang B, Yi W, Wang F, Wei S, Yan H, Qin P, Zou D, Wei R, Chen N
Journal of Inflammation Research 2021, 14:621-631
Published Date: 3 March 2021
The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways
Cao X, Li Y, Shi J, Tang H
Journal of Inflammation Research 2021, 14:611-619
Published Date: 26 February 2021
High Concentrations of Etanercept Reduce Human Islet Function and Integrity
Brandhorst D, Brandhorst H, Acreman S, Abraham A, Johnson PRV
Journal of Inflammation Research 2021, 14:599-610
Published Date: 26 February 2021
Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages
Hu TY, Zhang H, Chen YY, Jiao WH, Fan JT, Liu ZQ, Lin HW, Cheng BH
Journal of Inflammation Research 2021, 14:587-597
Published Date: 25 February 2021
Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A
Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J
Journal of Inflammation Research 2021, 14:575-586
Published Date: 25 February 2021
Markers of Chronic Inflammation in Overweight and Obese Individuals and the Role of Gender: A Cross-Sectional Study of a Large Cohort
Cohen E, Margalit I, Shochat T, Goldberg E, Krause I
Journal of Inflammation Research 2021, 14:567-573
Published Date: 25 February 2021
Crm1-Dependent Nuclear Export of Bach1 is Involved in the Protective Effect of Hyperoside on Oxidative Damage in Hepatocytes and CCl4-induced Acute Liver Injury
Cai Y, Li B, Peng D, Wang X, Li P, Huang M, Xing H, Chen J
Journal of Inflammation Research 2021, 14:551-565
Published Date: 25 February 2021
The Implications of Zinc Therapy in Combating the COVID-19 Global Pandemic
Samad N, Sodunke TE, Abubakar AR, Jahan I, Sharma P, Islam S, Dutta S, Haque M
Journal of Inflammation Research 2021, 14:527-550
Published Date: 26 February 2021
Plasma Neutrophil-to-Lymphocyte Ratio on the Third Day Postburn is Associated with 90-Day Mortality Among Patients with Burns Over 30% of Total Body Surface Area in Two Chinese Burns Centers
Qiu L, Jin X, Wang JJ, Tang XD, Fang X, Li SJ, Wang F, Chen XL
Journal of Inflammation Research 2021, 14:519-526
Published Date: 24 February 2021
AST-120 Improves Cardiac Dysfunction in Acute Kidney Injury Mice via Suppression of Apoptosis and Proinflammatory NF-κB/ICAM-1 Signaling
Shen WC, Chou YH, Shi LS, Chen ZW, Tu HJ, Lin XY, Wang GJ
Journal of Inflammation Research 2021, 14:505-518
Published Date: 24 February 2021
Potential Biomarkers for Diagnosing Major Depressive Disorder Patients with Suicidal Ideation
Bai S, Fang L, Xie J, Bai H, Wang W, Chen J
Journal of Inflammation Research 2021, 14:495-503
Published Date: 22 February 2021
Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells/Macrophage Co-Culture System
Meng YF, Pu Q, Dai SY, Ma Q, Li X, Zhu W
Journal of Inflammation Research 2021, 14:479-493
Published Date: 22 February 2021
Regulation of Pancreatic Fibrosis by Acinar Cell-Derived Exosomal miR-130a-3p via Targeting of Stellate Cell PPAR-γ
Wang Q, Wang H, Jing Q, Yang Y, Xue D, Hao C, Zhang W
Journal of Inflammation Research 2021, 14:461-477
Published Date: 24 February 2021
Therapeutic Potentials of Colocasia affinis Leaf Extract for the Alleviation of Streptozotocin-Induced Diabetes and Diabetic Complications: In vivo and in silico-Based Studies
Shill MC, Bepari AK, Khan M, Tasneem Z, Ahmed T, Hasan MA, Alam MJ, Hossain M, Rahman MA, Sharker SM, Shahriar M, Rahman GMS, Reza HM
Journal of Inflammation Research 2021, 14:443-459
Published Date: 19 February 2021
Distinctive Under-Expression Profile of Inflammatory and Redox Genes in the Blood of Elderly Patients with Cardiovascular Disease
Milanesi E, Manda G, Dobre M, Codrici E, Neagoe IV, Popescu BO, Bajenaru OA, Spiru L, Tudose C, Prada GI, Davidescu EI, Piñol-Ripoll G, Cuadrado A
Journal of Inflammation Research 2021, 14:429-442
Published Date: 18 February 2021
Comprehensive Analysis of LncRNA-mRNA Expression Profiles and the ceRNA Network Associated with Pyroptosis in LPS-Induced Acute Lung Injury
Luo D, Liu F, Zhang J, Shao Q, Tao W, Xiao R, Dai W, Ding C, Qian K
Journal of Inflammation Research 2021, 14:413-428
Published Date: 17 February 2021
Securidaca inappendiculata-Derived Xanthones Protected Joints from Degradation in Male Rats with Collagen-Induced Arthritis by Regulating PPAR-γ Signaling
Zuo J, Tao MQ, Wu XY, Jiang TT, Olatunji OJ, Dong J, Han J, Ji CL
Journal of Inflammation Research 2021, 14:395-411
Published Date: 16 February 2021
Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity [Erratum]
Chen Y, Cheng J, Zhang Y, Chen JDZ, Seralu FM
Journal of Inflammation Research 2021, 14:393-394
Published Date: 16 February 2021
Inflammatory Markers Related to Innate and Adaptive Immunity in Atherosclerosis: Implications for Disease Prediction and Prospective Therapeutics
Hong LZ, Xue Q, Shao H
Journal of Inflammation Research 2021, 14:379-392
Published Date: 16 February 2021
Adenosine A2A Receptor Agonist Polydeoxyribonucleotide Alleviates Interstitial Cystitis-Induced Voiding Dysfunction by Suppressing Inflammation and Apoptosis in Rats
Ko IG, Jin JJ, Hwang L, Kim SH, Kim CJ, Won KY, Na YG, Kim KH, Kim SJ
Journal of Inflammation Research 2021, 14:367-378
Published Date: 15 February 2021
Exposure to Maternal Immune Activation Causes Congenital Unfolded Protein Response Defects and Increases the Susceptibility to Postnatal Inflammatory Stimulation in Offspring
Shimizu Y, Tsukada T, Sakata-Haga H, Sakai D, Shoji H, Saikawa Y, Hatta T
Journal of Inflammation Research 2021, 14:355-365
Published Date: 12 February 2021
Iridin Prevented Against Lipopolysaccharide-Induced Inflammatory Responses of Macrophages via Inactivation of PKM2-Mediated Glycolytic Pathways
Ying ZH, Li HM, Yu WY, Yu CH
Journal of Inflammation Research 2021, 14:341-354
Published Date: 5 February 2021
Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity
Chen Y, Cheng J, Zhang Y, Chen JDZ, Seralu FM
Journal of Inflammation Research 2021, 14:325-339
Published Date: 5 February 2021
Association of a High Neutrophil-to-Lymphocyte Ratio with Hyperdense Artery Sign and Unfavorable Short-Term Outcomes in Patients with Acute Ischemic Stroke
Lin SK, Chen PY, Chen GC, Hsu PJ, Hsiao CL, Yang FY, Liu CY, Tsou A
Journal of Inflammation Research 2021, 14:313-324
Published Date: 5 February 2021
Aryl Hydrocarbon Receptor is Essential in the Control of Lung Club Cell Homeostasis
Liu KY, Wang LT, Wang HC, Wang SN, Tseng LW, Chai CY, Chiou SS, Huang SK, Hsu SH
Journal of Inflammation Research 2021, 14:299-311
Published Date: 5 February 2021
Analysis of the Effect of Proton-Pump Inhibitors on the Course of COVID-19
Zhang XY, Li T, Wu H, Ling Y, Qian ZP, Chen L
Journal of Inflammation Research 2021, 14:287-298
Published Date: 5 February 2021
CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets
Liu F, Wu H
Journal of Inflammation Research 2021, 14:267-285
Published Date: 5 February 2021
Association of Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study [Corrigendum]
Yousef AA, Mohamed FY, Boraey NF, Akeel NE, Soliman AA, Waked NM, Hashem MIA, Shehata H, Fahmy DS, Ismael A, Ibrahim LM, Ibrahim MAM, Salem HF, Yousry SM, Osman SF, Fouad RA, Enan ET, Attia MA, Afify MR, Zeidan NMS, Nashat M
Journal of Inflammation Research 2021, 14:265-266
Published Date: 4 February 2021

Overview on the Discovery and Development of Anti-Inflammatory Drugs: Should the Focus Be on Synthesis or Degradation of PGE2?


Mahesh G, Anil Kumar K, Reddanna P
Journal of Inflammation Research 2021, 14:253-263
Published Date: 3 February 2021
Neopterin: A Promising Candidate Biomarker for Severe COVID-19
Hailemichael W, Kiros M, Akelew Y, Getu S, Andualem H
Journal of Inflammation Research 2021, 14:245-251
Published Date: 2 February 2021
Clinical Implications of Intestinal Barrier Damage in Psoriasis
Sikora M, Stec A, Chrabaszcz M, Giebultowicz J, Samborowska E, Jazwiec R, Dadlez M, Olszewska M, Rudnicka L
Journal of Inflammation Research 2021, 14:237-243
Published Date: 27 January 2021
Inducing Apoptosis and Suppressing Inflammatory Reactions in Synovial Fibroblasts are Two Important Ways for Guizhi-Shaoyao-Zhimu Decoction Against Rheumatoid Arthritis
Zhang Q, Duan HX, Li RL, Sun JY, Liu J, Peng W, Wu CJ, Gao YX
Journal of Inflammation Research 2021, 14:217-236
Published Date: 26 January 2021
Nucleic Acid-Sensing Pathways During SARS-CoV-2 Infection: Expectations versus Reality
Mdkhana B, Saheb-Sharif Askari N, Ramakrishnan RK, Goel S, Hamid Q, Halwani R
Journal of Inflammation Research 2021, 14:199-216
Published Date: 26 January 2021
In vitro Phenotype Induction of Circulating Monocytes: CD16 and CD163 Analysis
Karsulovic C, Tempio F, Lopez M, Guerrero J, Goecke A
Journal of Inflammation Research 2021, 14:191-198
Published Date: 26 January 2021
Cytokine Storm and Mucus Hypersecretion in COVID-19: Review of Mechanisms
Khan MA, Khan ZA, Charles M, Pratap P, Naeem A, Siddiqui Z, Naqvi N, Srivastava S
Journal of Inflammation Research 2021, 14:175-189
Published Date: 22 January 2021

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease
Krawiec P, Pac-Kożuchowska E
Journal of Inflammation Research 2021, 14:163-174
Published Date: 22 January 2021
Studying Neutrophil Function in vitro: Cell Models and Environmental Factors
Blanter M, Gouwy M, Struyf S
Journal of Inflammation Research 2021, 14:141-162
Published Date: 20 January 2021
The Associations of Two Novel Inflammation Indexes, SII and SIRI with the Risks for Cardiovascular Diseases and All-Cause Mortality: A Ten-Year Follow-Up Study in 85,154 Individuals
Jin Z, Wu Q, Chen S, Gao J, Li X, Zhang X, Zhou Y, He D, Cheng Z, Zhu Y, Wu S
Journal of Inflammation Research 2021, 14:131-140
Published Date: 18 January 2021
The Role of Cancer-Elicited Inflammatory Biomarkers in Predicting Early Recurrence Within Stage II–III Colorectal Cancer Patients After Curable Resection
Liao YC, Ying HQ, Sun F, Peng HX, Cheng XX
Journal of Inflammation Research 2021, 14:115-129
Published Date: 18 January 2021
Identification of Prognostic Biomarkers and Molecular Targets Among JAK Family in Breast Cancer
Liu F, Wu H
Journal of Inflammation Research 2021, 14:97-114
Published Date: 14 January 2021
Selenium-Containing Amino Acids Protect Dextran Sulfate Sodium-Induced Colitis via Ameliorating Oxidative Stress and Intestinal Inflammation
Shi C, Yue F, Shi F, Qin Q, Wang L, Wang G, Mu L, Liu D, Li Y, Yu T, She J
Journal of Inflammation Research 2021, 14:85-95
Published Date: 14 January 2021
The Role of Regulatory B Cells in Health and Diseases: A Systemic Review
Chekol Abebe E, Asmamaw Dejenie T, Mengie Ayele T, Dagnew Baye N, Agegnehu Teshome A, Tilahun Muche Z
Journal of Inflammation Research 2021, 14:75-84
Published Date: 12 January 2021
Inhibition of Dectin-1 on Dendritic Cells Prevents Maturation and Prolongs Murine Islet Allograft Survival
Ren A, Li Z, Zhang X, Deng R, Ma Y
Journal of Inflammation Research 2021, 14:63-73
Published Date: 12 January 2021
Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B
Fettucciari K, Fruganti A, Marchegiani A, Brancorsini S, Marconi P, Bassotti G
Journal of Inflammation Research 2021, 14:57-62
Published Date: 11 January 2021

Understanding COVID-19 Pandemic: Molecular Mechanisms and Potential Therapeutic Strategies. An Evidence-Based Review


Hanna R, Dalvi S, Sălăgean T, Pop ID, Bordea IR, Benedicenti S
Journal of Inflammation Research 2021, 14:13-56
Published Date: 7 January 2021
Potential Impact of Local Anesthetics Inducing Granulocyte Arrest and Altering Immune Functions on Perioperative Outcome
Kolle G, Metterlein T, Gruber M, Seyfried T, Petermichl W, Pfaehler SM, Bitzinger D, Wittmann S, Bredthauer A
Journal of Inflammation Research 2021, 14:1-12
Published Date: 6 January 2021