Journal of Inflammation Research

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ISSN: 1178-7031

Sepsis and Systemic Inflammation


Section Editor(s):
Dr Ngo, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, CA, USA
Dr Du, Department of Pediatrics, University of California, San Diego, La Jolla, California, USA
Dr Sun, Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China

This section covers sepsis and Systemic Inflammatory Response Syndrome, including sepsis-associated inflammatory mediators, septic shock and potential immunotherapy in septic patients.

Latest articles in Sepsis and Systemic Inflammation:

- 25 records -

PD-1/TIGIT CD4⁺ T-Cell Signature for Risk Stratification of Post-Weaning Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients

Wang Z, Hao X, Han J, Li C, Wang L, Chen J, Chen J, Cao Y, Jiang Y, Ji H, Li J, Zhang J, Wang H, Hua M, Zeng H, Hou X, Chen C

Journal of Inflammation Research 2026, 19:609153

Published Date: 26 June 2026

The Dual Role of Natural Killer Cells in the Septic Liver

Wu X, Cheng J, Yu H, Ye J, Zhu H, Liu X

Journal of Inflammation Research 2026, 19:592210

Published Date: 23 June 2026

Platelet-to-White Blood Cell Ratio as a Predictor of ICU Mortality in Septic Shock and Heart Failure: A Real-World Validation Study Using the MIMIC-eICU and a Chinese Cohort

Liu Q, Tang W, Tan W, Min M, Tan X, Zhang M, Liu P

Journal of Inflammation Research 2026, 19:607253

Published Date: 19 June 2026

Short-Chain Fatty Acids: A Key Modulator of Sepsis-Associated Acute Respiratory Distress Syndrome

Sun Y, He M, Li J, Wu C, Pan S

Journal of Inflammation Research 2026, 19:608128

Published Date: 18 June 2026

Adult-Onset Still’s Disease in a Patient with Macrophage Activation Syndrome and Pre-Disseminated Intravascular Coagulation: A Case Report and Literature Review

Xu J, Yang J, Hu Y, Zhao Z, Cai H, Yao Q, Shang W

Journal of Inflammation Research 2026, 19:592591

Published Date: 12 June 2026

Early Risk Factors and Clinical Characteristics of Pediatric Hemophagocytic Lymphohistiocytosis: A Single-Center Retrospective Study

Wang Z, Geng Z, Xuan Y, Luo X

Journal of Inflammation Research 2026, 19:606555

Published Date: 11 June 2026

Unfractionated Heparin Attenuates Histone-Induced Pulmonary Endothelial Glycocalyx Injury: A Preliminary Study on the Roles of the ROCK Pathway and Heparanase‑1

Li X, Chi Y, Zhuo M, Li X, Zhu C, Li X

Journal of Inflammation Research 2026, 19:573499

Published Date: 8 June 2026

NHWD-870, a Potent BET Inhibitor, Ameliorated Endotoxemia-Induced Hepatic Inflammation via Suppression of BRD4-STAT1 Signaling and Macrophage M1 Polarization

Zhou N, Tan B, Jiang Y, Wang H, Peng W, Yin M, Fu L, Peng S

Journal of Inflammation Research 2026, 19:598139

Published Date: 6 June 2026

Lactate-Modified Prognostic Nutritional Index (LPNI) and Its Association with ICU Mortality in Patients with Sepsis: A Retrospective Cohort Study

Li X, Qian S, Chen H, Yuan X, Xia X, Gao X, Chen G

Journal of Inflammation Research 2026, 19:604786

Published Date: 28 May 2026

Prognostic Value of Serum MMP9 in Predicting Mortality Among Elderly Patients with Sepsis: A Prospective Cohort Study

Yan F, Liu T, Yuan L, Qiu Y, Huang S, Zhang L, Bai W, Zhang C, Peng X, Yang Y, Wang F

Journal of Inflammation Research 2026, 19:575317

Published Date: 12 May 2026

Brucella Infection Associated with Abdominal Aortic Rupture and Retroperitoneal Hematoma: A Case Report

Shao T, Chen N, Sun Q, Sheng P

Journal of Inflammation Research 2026, 19:598056

Published Date: 8 May 2026

Methodological and Clinical Gaps in Biomarker-Guided Weaning for Sepsis-Induced ARDS [Letter]

Lu CW, Chang KC

Journal of Inflammation Research 2026, 19:612924

Published Date: 25 April 2026

Exploring the Protective Mechanism of Xuebijing Injection Against Sepsis

Jiao Z, Yu H, Li X, Chen X, Jiao F, Feng T, Kong D, Jiang R, Jin J, Song Y, Luo X

Journal of Inflammation Research 2026, 19:586204

Published Date: 23 April 2026

Genetic and Experimental Evidence Implicates CCL4 in Severe Sepsis Risk and Phase-Dependent Immune Dynamics

Qin Q, Wang Y, Zhang L, Li Z, Wang J, Yu X

Journal of Inflammation Research 2026, 19:581720

Published Date: 20 April 2026

Cell Death Index Predicts Sepsis Outcomes and Highlights Necroptosis as a Therapeutic Target

Gan J, Long Q, Fang S, Song S, Wu J, Li X, Ye H, Gao Z, Zheng Y

Journal of Inflammation Research 2026, 19:577930

Published Date: 19 April 2026

Burns: The “Fuse” That Ignites Organ Crisis – A Narrative Review of Mechanisms and Crosstalk in Post-Burn MODS

He H, Zhang W, Huang R, Liu Y, Yao Y, Sun H, Xia Z, Ji S

Journal of Inflammation Research 2026, 19:582723

Published Date: 18 April 2026

Association of High-Sensitivity C-Reactive Protein with Metabolic Syndrome and Transitions in Metabolic Status: A Combined Cross-Sectional and Cohort Study with Gender Differences in Chinese Adults

Xiao Y, Zhang X, Wang J, Ma X, Sun B, Li Y, Chen L, Guo Y, Li X, Guo H, Yao S, Qin Y

Journal of Inflammation Research 2026, 19:588278

Published Date: 17 April 2026

The Role of Histone Modifications in Acute Lung Injury: Molecular Mechanisms and Potential of Traditional Chinese Medicine Treatment

Yan Z, Wang J, Qiao J, Xu Z, Wu S, Wang S, Jiao L, Guo T, Tan B, Yang A

Journal of Inflammation Research 2026, 19:588149

Published Date: 1 April 2026

Circulating and Respiratory Biomarkers in Sepsis-Induced ARDS: Diagnostic and Prognostic Insights – A Narrative Review

Muhoza BG, Liu S, Niyonkuru E, Sun T

Journal of Inflammation Research 2026, 19:571504

Published Date: 25 March 2026

The Diagnostic and Prognostic Value of Procalcitonin and High-Sensitivity C-Reactive Protein in Early-Stage Burn Sepsis: A Retrospective Cohort Study

Yang GX, Cui ZF, Zhao SS, Wu ZQ, Zhu C, Que T, Dou SQ, Wang X, Wang XL, Chen QJ, Liu XB, Liu W

Journal of Inflammation Research 2026, 19:571738

Published Date: 18 March 2026

Immunometabolic Reprogramming in Experimental Sepsis: A Driver of Multiple Organ Dysfunction Syndrome

Wu F, Chen Y, Chen L, Wei X, Zhang L, Shen Y

Journal of Inflammation Research 2026, 19:577143

Published Date: 4 March 2026


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