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International Journal of Chronic Obstructive Pulmonary Disease
ISSN: 1178-2005
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Archive: Volume 17, 2022
COPD Exacerbation Syndrome: The Spanish Perspective on an Old Dilemma
Soler-Cataluña JJ, Lopez-Campos JL
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3139-3149
Published Date: 29 December 2022
External Validation and User Experiences of the ProPal-COPD Tool to Identify the Palliative Phase in COPD
Broese JMC, van der Kleij RMJJ, Verschuur EML, Kerstjens HAM, Bronkhorst EM, Chavannes NH, Engels Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3129-3138
Published Date: 22 December 2022
Stability of Blood Eosinophils in COPD with Multiple Acute Exacerbations Within 1 Year and Its Relationship with Prognosis
Gong Y, Sun H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3123-3128
Published Date: 22 December 2022
Chronic Obstructive Pulmonary Disease is Not Associated with In-Hospital Mortality in COVID-19: An Observational Cohort Analysis
Toppen W, Yan P, Markovic D, Shover CM, Buhr RG, Fulcher JA, Tashkin DP, Barjaktarevic I
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3111-3121
Published Date: 19 December 2022

Cost-Effectiveness of Once-Daily Single-Inhaler COPD Triple Therapy in Spain: IMPACT Trial
Paly VF, Vallejo-Aparicio LA, Martin A, Izquierdo JL, Riesco JA, Soler-Cataluña JJ, Abreu C, Biswas C, Ismaila AS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3097-3109
Published Date: 16 December 2022
Performance of the Cough and Sputum Assessment Questionnaire (CASA-Q) in COPD: Evidence from Clinical and Online Patient Interaction Studies
Patalano F, Hache C, Pethe A, Kaur H, Leidy NK, Arsiwala T, Afroz N, Gutzwiller FS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3087-3096
Published Date: 10 December 2022
Breathing Exercises in the Treatment of COPD: An Overview of Systematic Reviews
Li Y, Ji Z, Wang Y, Li X, Xie Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3075-3085
Published Date: 7 December 2022
Benefits of Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate on COPD Exacerbations, Lung Function, Symptoms, and Quality of Life Across Blood Eosinophil Ranges: A Post-Hoc Analysis of Data from ETHOS

Bafadhel M, Rabe KF, Martinez FJ, Singh D, Darken P, Jenkins M, Aurivillius M, Patel M, Dorinsky P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3061-3073
Published Date: 6 December 2022
Relationship Between COPD and GERD: A Bibliometrics Analysis
Zou M, Zhang W, Xu Y, Zhu Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3045-3059
Published Date: 6 December 2022
Discriminant Validity of a Single Clinical Question for the Screening of Inactivity in Individuals Living with COPD
Ramon MA, Esteban C, Ortega F, Cebollero P, Carrascosa I, Martinez-González C, Sobradillo P, Soler-Cataluña JJ, Miravitlles M, García-Río F
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3033-3044
Published Date: 2 December 2022
Effectiveness of Extrafine Single Inhaler Triple Therapy in Chronic Obstructive Pulmonary Disease (COPD) in Germany – The TriOptimize Study
Gessner C, Trinkmann F, Bahari Javan S, Hövelmann R, Bogoevska V, Georges G, Nudo E, Criée CP
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3019-3031
Published Date: 2 December 2022
Updated Perspectives on the Role of Biomechanics in COPD: Considerations for the Clinician [Letter]
Bordoni B
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3017-3018
Published Date: 30 November 2022
Identification of Small Airway Epithelium-Related Hub Genes in Chronic Obstructive Pulmonary Disease
Lin L, Lin G, Chen X, Lin H, Lin Q, Zeng Y, Xu Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3001-3015
Published Date: 30 November 2022

Cost-Effectiveness of Triple Therapy with Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate versus Dual Therapies in Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease: United Kingdom Analysis Using the ETHOS Study
de Nigris E, Treharne C, Brighton N, Holmgren U, Walker A, Haughney J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2987-3000
Published Date: 22 November 2022
Acoustic Monitoring of Night-Time Respiratory Symptoms in 14 Patients with Exacerbated COPD Over a 3- Week Period
Boeselt T, Kroenig J, Lueders TS, Koehler N, Beutel B, Hildebrandt O, Koehler U, Conradt R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2977-2986
Published Date: 18 November 2022
Update on the Etiology, Assessment, and Management of COPD Cachexia: Considerations for the Clinician
De Brandt J, Beijers RJHCG, Chiles J, Maddocks M, McDonald MLN, Schols AMWJ, Nyberg A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2957-2976
Published Date: 18 November 2022
A Longitudinal Study of Trajectories and Factors Influencing Patient-Reported Outcomes in Chronic Obstructive Pulmonary Disease
Cai M, Cui M, Nong Y, Qin J, Mo S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2945-2956
Published Date: 18 November 2022

A Telemedicine Approach for Monitoring COPD: A Prospective Feasibility and Acceptability Cohort Study
Shinoda M, Hataji O, Miura M, Kinoshita M, Mizoo A, Tobino K, Soutome T, Nishi T, Ishii T, Miller BE, Tal-Singer R, Tomlinson R, Matsuki T, Jones PW, Shibata Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2931-2944
Published Date: 17 November 2022

Association Between Empirical Anti-Pseudomonal Antibiotics for Recurrent Lower Respiratory Tract Infections and Mortality: A Retrospective Cohort Study
Shiroshita A, Yamamoto S, Anan K, Suzuki H, Takeshita M, Kataoka Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2919-2929
Published Date: 17 November 2022
Cost-Effectiveness Analysis of Triple Therapy with Budesonide/ Glycopyrronium/ Formoterol Fumarate versus Dual Therapy in Patients with Chronic Obstructive Pulmonary Disease in Spain
Trigueros JA, Garin N, Baloira A, Aceituno S, Calvo A, Prades M, Touron C, Martínez A, Torres C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2905-2917
Published Date: 15 November 2022
Effect of Singing on Symptoms in Stable COPD: A Systematic Review and Meta-Analysis
Fang X, Qiao Z, Yu X, Tian R, Liu K, Han W
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2893-2904
Published Date: 14 November 2022
Differential Expression of Serum Proteins in Chronic Obstructive Pulmonary Disease Assessed Using Label-Free Proteomics and Bioinformatics Analyses
Li R, Zhao X, Liu P, Wang D, Chen C, Wang Y, Zhang N, Shen B, Zhao D
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2871-2891
Published Date: 15 November 2022
Effects of High-Frequency Chest Wall Oscillation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Huang HP, Chen KH, Tsai CL, Chang WP, Chiu SYH, Lin SR, Lin YH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2857-2869
Published Date: 10 November 2022
Association Between Blood Urea Nitrogen Levels and Length of Stay in Patients with Pneumonic Chronic Obstructive Pulmonary Disease Exacerbation: A Secondary Analysis Based on a Multicentre, Retrospective Cohort Study
Du J, Niu J, Ma L, Sui Y, Wang S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2847-2856
Published Date: 9 November 2022
Validation of the Spanish Activity Questionnaire in COPD (SAQ-COPD) in Patients with Chronic Obstructive Pulmonary Disease
Soler-Cataluña JJ, Puente Maestu L, Román Rodríguez M, Esteban C, Gea J, Bernabeu Mora R, Pleguezuelos Cobo E, Ancochea J, García-Río F
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2835-2846
Published Date: 5 November 2022
Plasma Extracellular Vesicle miRNA Profiles Distinguish Chronic Obstructive Pulmonary Disease Exacerbations and Disease Severity
O'Farrell HE, Bowman RV, Fong KM, Yang IA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2821-2833
Published Date: 4 November 2022

Physical Activity, Muscle Oxidative Capacity, and Coronary Artery Calcium in Smokers with and without COPD
Tiller NB, Kinninger A, Abbasi A, Casaburi R, Rossiter HB, Budoff MJ, Adami A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2811-2820
Published Date: 3 November 2022
Ultrasound Assessment of the Rectus Femoris in Patients with Chronic Obstructive Pulmonary Disease Predicts Sarcopenia
Deng M, Yan L, Tong R, Zhao J, Li Y, Yin Y, Zhang Q, Gao J, Wang Q, Hou G, Zhou X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2801-2810
Published Date: 2 November 2022
The Prognostic Performance of Lung Diffusing Capacity in Preserved Ratio Impaired Spirometry: An Observational Cohort Study
Ogata H, Sha K, Kotetsu Y, Enokizu-Ogawa A, Katahira K, Ishimatsu A, Taguchi K, Moriwaki A, Yoshida M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2791-2799
Published Date: 28 October 2022
Sinonasal Symptoms in COPD: Burden and Associations with Clinical Markers of Disease [Corrigendum]
Øie MR, Helvik AS, Sue-Chu M, Steinsvåg SK, Thorstensen WM
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2789-2790
Published Date: 28 October 2022
Effectiveness of Hospital Pharmacist Interventions for COPD Patients: A Systematic Literature Review and Logic Model
Lin G, Zheng J, Tang PK, Zheng Y, Hu H, Ung COL
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2757-2788
Published Date: 25 October 2022
Cost-Effectiveness of Single- versus Multiple-Inhaler Triple Therapy in a UK COPD Population: The INTREPID Trial
Halpin DM, Kendall R, Shukla S, Martin A, Shah D, Midwinter D, Beeh KM, Kocks JWH, Jones PW, Compton C, Risebrough NA, Ismaila AS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2745-2755
Published Date: 25 October 2022
Functional Predictors Discriminating Asthma–COPD Overlap (ACO) from Chronic Obstructive Pulmonary Disease (COPD)
Kraemer R, Gardin F, Smith HJ, Baty F, Barandun J, Piecyk A, Minder S, Salomon J, Frey M, Brutsche MH, Matthys H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2723-2743
Published Date: 21 October 2022
Superior Predictive Value of D-Dimer to the Padua Prediction Score for Venous Thromboembolism in Inpatients with AECOPD: A Multicenter Cohort Study
Zhou C, Guang Y, Luo Y, Ge H, Wei H, Liu H, Zhang J, Pan P, Zhang J, Peng L, Aili A, Liu Y, Pu J, Zhong X, Wang Y, Yi Q, Zhou H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2711-2722
Published Date: 21 October 2022

Using Machine Learning to Predict Likelihood and Cause of Readmission After Hospitalization for Chronic Obstructive Pulmonary Disease Exacerbation
Bonomo M, Hermsen MG, Kaskovich S, Hemmrich MJ, Rojas JC, Carey KA, Venable LR, Churpek MM, Press VG
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2701-2709
Published Date: 20 October 2022
Guidance Value of Procalcitonin Detection in Selecting Switching Points for Sequential Therapy in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure
Ding F, Liu W, Wang H, Wang W, Yang C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2693-2699
Published Date: 18 October 2022
The Relationship Between BMI and Lung Function in Populations with Different Characteristics: A Cross-Sectional Study Based on the Enjoying Breathing Program in China
Tang X, Lei J, Li W, Peng Y, Wang C, Huang K, Yang T
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2677-2692
Published Date: 18 October 2022
Updated Perspectives on the Role of Biomechanics in COPD: Considerations for the Clinician
Yentes JM, Liu WY, Zhang K, Markvicka E, Rennard SI
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2653-2675
Published Date: 17 October 2022
A 4-Year Retrospective Claims Analysis of Oral Corticosteroid Use and Health Conditions in Newly Diagnosed Medicare FFS Patients with COPD
Bazell C, Pollack M, Comellas AP, Sethi S, Alston M, Pyenson B, Hansen D, Caplen M, Staresinic A, Styczynski J, Feigler N
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2635-2652
Published Date: 17 October 2022
Bronchodilator Responsiveness Defined by the 2005 and 2021 ERS/ATS Criteria in Patients with Asthma as Well as Chronic Obstructive Pulmonary Disease
Li Y, Lin J, Wang Z, Wang Z, Tan L, Liu S, Huang J, Gao Y, Zheng J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2623-2633
Published Date: 17 October 2022

From COPD to Lung Cancer: Mechanisms Linking, Diagnosis, Treatment, and Prognosis

Qi C, Sun SW, Xiong XZ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2603-2621
Published Date: 17 October 2022
IL-17A Promotes Epithelial ADAM9 Expression in Cigarette Smoke-Related COPD
Li D, Wang T, Ma Q, Zhou L, Le Y, Rao Y, Jin L, Pei Y, Cheng Y, Huang C, Gai X, Sun Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2589-2602
Published Date: 14 October 2022
Impact of Spirometrically Confirmed Chronic Obstructive Pulmonary Disease on Arterial Stiffness and Surfactant Protein D After Percutaneous Coronary Intervention. The CATEPOC Study
Malik K, Diaz-Coto S, de la Asunción Villaverde M, Martinez-Camblor P, Navarro-Rolon A, Pujalte F, De la Sierra A, Almagro P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2577-2587
Published Date: 14 October 2022
Clinical Indicators for Asthma-COPD Overlap: A Systematic Review and Meta-Analysis
Peng J, Wang M, Wu Y, Shen Y, Chen L
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2567-2575
Published Date: 12 October 2022
When Treatment of Pulmonary Emphysema with Endobronchial Valves Did Not Work: Evaluation of Quantitative CT Analysis and Pulmonary Function Tests Before and After Valve Explantation
Leppig JA, Song L, Voigt DC, Feldhaus FW, Ruwwe-Gloesenkamp C, Saccomanno J, Lassen-Schmidt BC, Neumann K, Leitner K, Hubner RH, Doellinger F
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2553-2566
Published Date: 11 October 2022
Disability Retirement After First Admission with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Danish Nationwide Registry Cohort Study Using a Retrospective Follow-Up Design
Jacobsen PA, Kragholm K, Torp-Pedersen C, Møller Weinreich U
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2541-2551
Published Date: 11 October 2022
Association Between Anthropometric Indices and Skeletal-Muscle Atrophy in Chinese Patients with Stable Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Han Y, Wu Z, Zhao Q, Jiang B, Miao X, Lu X, Qian H, Niu M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2529-2539
Published Date: 11 October 2022
Elevated HsCRP in Chronic Obstructive Pulmonary Disease: A Prospective Study of Long-Term Outcomes After Percutaneous Coronary Intervention
Zheng Y, Qi Y, Seery S, Yang J, Li C, Wang W, Gao J, Meng X, Shao C, Tang YD
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2517-2528
Published Date: 7 October 2022
Revealing lncRNA Biomarkers Related to Chronic Obstructive Pulmonary Disease Based on Bioinformatics
Han H, Hao L
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2487-2515
Published Date: 4 October 2022
The Quantitative Computed Tomography Techniques are Alternate Modalities of Assessing the Disease Profile of COPD Instead of Pulmonary Function Testing Under COVID-19 Pandemic [Letter]
Teramoto S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2485-2486
Published Date: 5 October 2022

Re-Defining High Risk COPD with Parameter Response Mapping Based on Machine Learning Models
Pu Y, Zhou X, Zhang D, Guan Y, Xia Y, Tu W, Lu Y, Zhang W, Fu CC, Fang Q, de Bock GH, Liu S, Fan L
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2471-2483
Published Date: 4 October 2022
Six-Minute Walking Test and 30 Seconds Chair-Stand-Test as Predictors of Mortality in COPD – A Cohort Study
Höglund J, Boström C, Sundh J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2461-2469
Published Date: 4 October 2022
Elevated Blood Glucose is Associated with Severe Exacerbation of Chronic Obstructive Pulmonary Disease
Chen G, Lin Q, Zhuo D, Cui J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2453-2459
Published Date: 1 October 2022

The Effect of Maintenance Treatment with Erdosteine on Exacerbation Treatment and Health Status in Patients with COPD: A Post-Hoc Analysis of the RESTORE Dataset [Corrigendum]
Calverley PMA, Papi A, Page C, Rogliani P, Dal Negro RW, Cazzola M, Cicero AF, Wedzicha JA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2451-2452
Published Date: 3 October 2022
DNA Methylation Profiling in a Cigarette Smoke-Exposed Mouse Model of Airway Inflammation
Li P, Peng J, Chen G, Chen F, Shen Y, Liu L, Chen L
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2443-2450
Published Date: 1 October 2022
Prevalence of Chronic Obstructive Pulmonary Disease in an Urban Area. Changes in COPD Ten Years on
García Castillo E, Alonso Pérez T, Peláez A, Pérez González P, Soriano JB, Ancochea J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2431-2441
Published Date: 29 September 2022

Comparative Adherence and Persistence of Single- and Multiple-Inhaler Triple Therapies Among Patients with Chronic Obstructive Pulmonary Disease in an English Real-World Primary Care Setting
Halpin DM, Rothnie KJ, Banks V, Czira A, Compton C, Wood R, Tritton T, Massey O, Wild R, Snowise N, Nikitin K, Sharma R, Ismaila AS, Vogelmeier CF
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2417-2429
Published Date: 24 September 2022

Suboptimal Peak Inspiratory Flow and Critical Inhalation Errors are Associated with Higher COPD-Related Healthcare Costs
Leving MT, van Boven JFM, Bosnic-Anticevich SZ, van Cooten J, Correia de Sousa J, Cvetkovski B, Dekhuijzen R, Dijk L, García Pardo M, Gardev A, Gawlik R, van der Ham I, Hartgers-Gubbels ES, Janse Y, Lavorini F, Maricoto T, Meijer J, Metz B, Price DB, Roman-Rodríguez M, Schuttel K, Stoker N, Tsiligianni I, Usmani OS, Kocks JH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2401-2415
Published Date: 25 September 2022

Myostatin/HIF2α-Mediated Ferroptosis is Involved in Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease
Zhang L, Li D, Chang C, Sun Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2383-2399
Published Date: 24 September 2022
Patient Perceptions of Switching to a Generic Dry Powder Inhaler – Increased Understanding Through Journey Mapping [Corrigendum]
Ray SE, Boudewyns V, Davis C, Tzeng JP, Srivastava I, Oguntimein O, Conti DS, Feibus KB
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2381-2382
Published Date: 25 September 2022
Cost-Effectiveness Analysis of the TCM “Yupingfeng Granules” in the Treatment of Acute Exacerbations of COPD Based on a Randomized Clinical Trial
Hu M, Ding P, Ma J, Yang N, Zheng J, Zhou N
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2369-2379
Published Date: 23 September 2022

Real-World Treatment of Patients Newly Diagnosed with Chronic Obstructive Pulmonary Disease: A Retrospective German Claims Data Analysis
Buhl R, Wilke T, Picker N, Schmidt O, Hechtner M, Kondla A, Maywald U, Vogelmeier CF
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2355-2367
Published Date: 22 September 2022
Metabolomics Reveals Dysregulated Sphingolipid and Amino Acid Metabolism Associated with Chronic Obstructive Pulmonary Disease
Kim J, Suresh B, Lim MN, Hong SH, Kim KS, Song HE, Lee HY, Yoo HJ, Kim WJ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2343-2353
Published Date: 21 September 2022

Characteristics of 12-Month Readmission for Hospitalized Patients with COPD: A Propensity Score Matched Analysis of Prospective Multicenter Study
Xu T, Sun W, Zhao H, Wang X, Yuan Q, Zhang X, Mao S, Zhang X, Zhao M, Sheng Z, Zhang M, Huang M, Ji N
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2329-2341
Published Date: 20 September 2022

Chronic Obstructive Pulmonary Disease Prevalence and Associated Risk Factors in Adults Aged 40 Years and Older in Southeast China: A Cross-Sectional Study During 2019–2020
Chen J, Yin Y, Zhang Y, Lin X, Chen T, Yang Z, Wang D, Zhong W
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2317-2328
Published Date: 17 September 2022
Radiographic Phenotypes Affect the Risk of Inhaled Corticosteroid-Associated Pneumonia in Patients with COPD
Lee HJ, Jin KN, Lee HW, Lee JK, Park TY, Heo EY, Kim DK
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2301-2315
Published Date: 18 September 2022

Evaluation of the Individual Activity Descriptors of the mMRC Breathlessness Scale: A Mixed Method Study
Yorke J, Khan N, Garrow A, Tyson S, Singh D, Vestbo J, Jones PW
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2289-2299
Published Date: 15 September 2022
Perceptions and Attitudes of Patients and Their Family Caregivers on Nebulization Therapy for COPD
Dumra H, Khanna A, Madhukar SK, Lopez M, Gogtay J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2277-2288
Published Date: 14 September 2022
Association of Red Cell Index and Adverse Hospitalization Outcomes in Chronic Obstructive Pulmonary Disease Patients with Acute Exacerbation: A Retrospective Cohort Study
Yuan F, Shui W, Xing Y, Niu Y, Zhang X, Zhang C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2263-2275
Published Date: 15 September 2022

The Influence of Influenza Virus Infections in Patients with Chronic Obstructive Pulmonary Disease
Liao KM, Chen YJ, Shen CW, Ou SK, Chen CY
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2253-2261
Published Date: 14 September 2022
Correlations of Computed Tomography Measurement of Distal Pulmonary Vascular Pruning with Airflow Limitation and Emphysema in COPD Patients
Tang G, Wang F, Liang Z, Liang C, Wang J, Yang Y, Tang W, Shi W, Tang G, Yang K, Wang Z, Li Q, Li H, Xu J, Chen D, Chen R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2241-2252
Published Date: 14 September 2022
Effect of Macrolide Antibiotics on In-Hospital Mortality Among Acute Exacerbation of COPD Patients: A Propensity Score-Matched Analysis
Morasert T, Kriengwattanakul O, Kulalert P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2229-2239
Published Date: 13 September 2022
Comparison of Ultrasound Measurements for Diaphragmatic Mobility, Diaphragmatic Thickness, and Diaphragm Thickening Fraction with Each Other and with Lung Function in Patients with Chronic Obstructive Pulmonary Disease
Schulz A, Erbuth A, Boyko M, Vonderbank S, Gürleyen H, Gibis N, Bastian A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2217-2227
Published Date: 12 September 2022

Efficacy of Vitamin C Supplementation on Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review and Meta-Analysis
Lei T, Lu T, Yu H, Su X, Zhang C, Zhu L, Yang K, Liu J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2201-2216
Published Date: 10 September 2022

Patients with Chronic Obstructive Pulmonary Disease and Evidence of Eosinophilic Inflammation Experience Exacerbations Despite Receiving Maximal Inhaled Maintenance Therapy
Chen S, Miravitlles M, Rhee CK, Pavord ID, Jones R, Carter V, Emmanuel B, Alacqua M, Price DB
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2187-2200
Published Date: 9 September 2022
The Relationship of Low-Density-Lipoprotein to Lymphocyte Ratio with Chronic Obstructive Pulmonary Disease
Huang Y, Ding K, Dai Z, Wang J, Hu B, Chen X, Xu Y, Yu B, Huang L, Liu C, Zhang X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2175-2185
Published Date: 8 September 2022

Clinical and Economic Impact of Long-Term Inhaled Corticosteroid Withdrawal in Patients with Chronic Obstructive Pulmonary Disease Treated with Triple Therapy in Spain
Neches García V, Vallejo-Aparicio LA, Ismaila AS, Sicras-Mainar A, Sicras-Navarro A, González C, Cuervo R, Shukla S, García-Peñuela M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2161-2174
Published Date: 7 September 2022

Costs and Clinical Consequences of Compliance with COPD GOLD Recommendations or National Guidelines Compared with Current Clinical Practice in Belgium, Germany, Sweden, and the United States
Sethi S, Wright A, Hartgers-Gubbels ES, Hechtner M, Clark B, Wright C, Langham S, Buhl R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2149-2160
Published Date: 7 September 2022
Sinonasal Symptoms in COPD: Burden and Associations with Clinical Markers of Disease
Øie MR, Helvik AS, Sue-Chu M, Steinsvåg SK, Thorstensen WM
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2137-2147
Published Date: 7 September 2022

New Perspectives on Chronic Obstructive Pulmonary Disease
Celli BR, Singh D, Vogelmeier C, Agusti A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2127-2136
Published Date: 6 September 2022
SERPINA1 Methylation Levels are Associated with Lung Cancer Development in Male Patients with Chronic Obstructive Pulmonary Disease
Zhang LY, Sun XW, Ding YJ, Yan YR, Wang Y, Li CX, Li SQ, Zhang L, Song HJ, Li HP, Li QY
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2117-2125
Published Date: 6 September 2022
Correlation Analysis of Early Renal Injury in Elderly Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Zhang D
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2109-2115
Published Date: 6 September 2022
Hospital Cost Savings for Sequential COPD Patients Receiving Domiciliary Nasal High Flow Therapy [Corrigendum]
Milne RJ, Hockey HU, Garrett J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2107-2108
Published Date: 6 September 2022

Development and Validation of a Multivariable Prediction Model to Identify Acute Exacerbation of COPD and Its Severity for COPD Management in China (DETECT Study): A Multicenter, Observational, Cross-Sectional Study
Yin Y, Xu J, Cai S, Chen Y, Chen Y, Li M, Zhang Z, Kang J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2093-2106
Published Date: 5 September 2022
Circ_0040929 Serves as Promising Biomarker and Potential Target for Chronic Obstructive Pulmonary Disease
Miao Y, Wu J, Wu R, Wang E, Wang J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2079-2092
Published Date: 7 September 2022
Shared Decision-Making Facilitates Inhaler Choice in Patients with Newly-Diagnosed Chronic Obstructive Pulmonary Disease: A Multicenter Prospective Study
Hsiao YH, Tseng CM, Sheu CC, Wang HY, Ko HK, Su KC, Tao CW, Tsai MJ, Chen YF
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2067-2078
Published Date: 2 September 2022
Influences of Two FEV1 Reference Equations (GLI-2012 and GIRH-2017) on Airflow Limitation Classification Among COPD Patients
Wei D, Wang Q, Liu S, Tan X, Chen L, Tu R, Liu Q, Jia Y, Liu S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2053-2065
Published Date: 2 September 2022
Effect of Recent Exacerbation History on the Efficacy of Once-Daily Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol Triple Therapy in Patients with Chronic Obstructive Pulmonary Disease in the FULFIL Trial
Panettieri Jr RA, Camargo CA Jr, Cheema T, El Bayadi SG, Fiel S, Vila TM, Jain RG, Midwinter D, Thomashow B, Ludwig-Sengpiel A, Lipson DA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2043-2052
Published Date: 1 September 2022
A Real-World Study on the Day and Night-Time Symptoms Among Greek COPD Patients Who Recently Initiated Treatment with Dual Bronchodilation: The DANICO Study
Kostikas K, Dimakou K, Gourgoulianis K, Gaga M, Papapetrou D, Tsoukalas G, Chatziapostolou P, Antoniadis A, Meletis G, Evangelopoulou E, Styliara P, Karypidou I, Gogali A, Kalafatakis K, Tzanakis N
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2027-2041
Published Date: 1 September 2022
Phenotyping COPD Patients with Emphysema Distribution Using Quantitative CT Measurement; More Severe Airway Involvement in Lower Dominant Emphysema
Park J, Kim EK, Lee SH, Kim MA, Kim JH, Lee SM, Lee JS, Oh YM, Lee SD, Lee JH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2013-2025
Published Date: 31 August 2022
The Association of Renin-Angiotensin System Blockades and Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Acute Respiratory Failure: A Retrospective Cohort Study
Ruan Z, Li D, Hu Y, Qiu Z, Chen X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2001-2011
Published Date: 1 September 2022

High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation for AECOPD Patients After Extubation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Feng Z, Zhang L, Yu H, Su X, Shuai T, Zhu L, Chen D, Liu J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1987-1999
Published Date: 30 August 2022

Single-Inhaler Triple versus Dual Bronchodilator Therapy in COPD: Real-World Comparative Effectiveness and Safety
Suissa S, Dell'Aniello S, Ernst P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1975-1986
Published Date: 30 August 2022
Consistency Evaluation of Two Loading Devices in Measuring the Perception of Dyspnea
Song J, Yin D, Liu X, Li X, Huang K
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1963-1973
Published Date: 26 August 2022
Contributions of Emphysema and Functional Small Airway Disease on Intrapulmonary Vascular Volume in COPD
Huang X, Yin W, Shen M, Wang X, Ren T, Wang L, Liu M, Guo Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1951-1961
Published Date: 25 August 2022
Pulmonary Arterial Pressure Changes Under Dobutamine Stress Echocardiography in Non-Anemic Iron Deficient COPD Subjects
Wanderley Xavier AC, Koch R, Steinhorst Goelzer L, Muller PT
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1943-1949
Published Date: 24 August 2022

Treatment Burden Discussion in Clinical Encounters: Priorities of COPD Patients, Carers and Physicians
Sav A, Thomas ST, Cardona M, Michaleff ZA, Dobler CC
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1929-1942
Published Date: 23 August 2022

SWEmean of Quadriceps, a Potential Index of Complication Evaluation to Patients with Chronic Obstructive Pulmonary Disease


Niu Y, Yue Y, Zheng Y, Long C, Li Q, Chen Y, Chen Z, Ma X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1921-1928
Published Date: 23 August 2022



The Effect of Maintenance Treatment with Erdosteine on Exacerbation Treatment and Health Status in Patients with COPD: A Post-Hoc Analysis of the RESTORE Dataset


Calverley PMA, Papi A, Page C, Rogliani P, Dal Negro RW, Cazzola M, Cicero AF, Wedzicha JA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1909-1920
Published Date: 22 August 2022
Sputum Cytokine Profiling in COPD: Comparison Between Stable Disease and Exacerbation
Barta I, Paska C, Antus B
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1897-1908
Published Date: 19 August 2022

The CO-MIND Study: Chronic Obstructive Pulmonary Disease Management in Daily Practice and Its Implications for Improved Outcomes According to GOLD 2019 Perspective
Gunen H, Kokturk N, Naycı S, Ozkaya S, Yıldız BP, Turan O, Gumus A, Akgun M, Gurgun A, Ogus C, Mirici A, Sen E, Bayram N, Eken V, Erkus H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1883-1895
Published Date: 18 August 2022
Efficacy of Repeating Pulmonary Rehabilitation in People with COPD: A Systematic Review
Burge AT, Malaguti C, Hoffman M, Shiell A, McDonald CF, Berlowitz DJ, Holland AE
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1871-1882
Published Date: 17 August 2022
The Role of the Clinical Pharmacist on the Health Outcomes of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD)
Gong Y, Chen Q, Zhang Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1863-1870
Published Date: 15 August 2022

Inducible Costimulator-C-X-C Motif Chemokine Receptor 3 Signaling is Involved in Chronic Obstructive Pulmonary Disease Pathogenesis
Li DY, Chen L, Miao SY, Zhou M, Wu JH, Sun SW, Liu LL, Qi C, Xiong XZ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1847-1861
Published Date: 13 August 2022

The Microbiome in COPD: Emerging Potential for Microbiome-Targeted Interventions
Millares L, Monso E
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1835-1845
Published Date: 12 August 2022
Emergency Department Visits Due to Dyspnea: Association with Inhalation Therapy in COPD and Cases with Adverse Drug Reactions
Bergs I, Just KS, Müller A, Stingl JC, Dreher M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1827-1834
Published Date: 11 August 2022

Identification and Validation of CDKN1A and HDAC1 as Senescence-Related Hub Genes in Chronic Obstructive Pulmonary Disease
Yang J, Zhang MY, Du YM, Ji XL, Qu YQ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1811-1825
Published Date: 10 August 2022
Association Between Red Blood Cell Distribution Width–Albumin Ratio and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Study

Qiu Y, Wang Y, Shen N, Wang Q, Chai L, Liu J, Chen Y, Li M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1797-1809
Published Date: 10 August 2022

Characterization of Patients with Chronic Obstructive Pulmonary Disease Initiating Single-Inhaler Long-Acting Muscarinic Antagonist/Long-Acting β2-Agonist Dual Therapy in a Primary Care Setting in England
Requena G, Banks V, Czira A, Wood R, Tritton T, Wild R, Compton C, Duarte M, Ismaila AS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1781-1795
Published Date: 10 August 2022

Lack of COPD-Related Follow-Up Visits and Pharmacological Treatment in Swedish Primary and Secondary Care
Sandelowsky H, Janson C, Wiklund F, Telg G, de Fine Licht S, Ställberg B
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1769-1780
Published Date: 9 August 2022

Patient Perceptions of Switching to a Generic Dry Powder Inhaler – Increased Understanding Through Journey Mapping
Ray SE, Boudewyns V, Davis C, Tzeng JP, Srivastava I, Oguntimein O, Conti DS, Feibus KB
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1751-1768
Published Date: 6 August 2022
Bronchoscopic Treatment of Giant Emphysematous Bullae with Endobronchial Silicone Plugs
Lin H, Zhang H, Yang D, Chen X, Chen Y, Song D, Cai C, Zeng Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1743-1750
Published Date: 3 August 2022
Long-Term Follow-Up of Intralobar Bullae After Endobronchial Valve Treatment for Emphysema
Taton O, Heinen V, Bondue B, Slebos DJ, Shah PL, Carron K, Moens O, Leduc D
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1735-1742
Published Date: 2 August 2022

Risk Assessment of Acute Myocardial Infarction and Stroke Associated with Long-Acting Muscarinic Antagonists, Alone or in Combination, versus Long-Acting beta2-Agonists
Rebordosa C, Plana E, Rubino A, Aguado J, Martinez D, Lei A, Daoud S, Saigi-Morgui N, Perez-Gutthann S, Rivero-Ferrer E
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1715-1733
Published Date: 2 August 2022

Disease Progression and Age as Factors Underlying Multimorbidity in Patients with COPD: Results from COSYCONET
Alter P, Kahnert K, Trudzinski FC, Bals R, Watz H, Speicher T, Söhler S, Andreas S, Welte T, Rabe KF, Wouters EFM, Sassmann-Schweda A, Wirtz H, Ficker JH, Vogelmeier CF, Jörres RA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1703-1713
Published Date: 29 July 2022

Health Inequality in the Global Burden of Chronic Obstructive Pulmonary Disease: Findings from the Global Burden of Disease Study 2019
Li H, Liang H, Wei L, Shi D, Su X, Li F, Zhang J, Wang Z
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1695-1702
Published Date: 28 July 2022


Short-Term Oxygen Therapy Outcomes in COPD
Soumagne T, Maltais F, Corbeil F, Paradis B, Baltzan M, Simão P, Abad Fernández A, Lecours R, Bernard S, Lacasse Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1685-1693
Published Date: 28 July 2022

Role of Genetic Polymorphisms in IL12Rβ2 in Chronic Obstructive Pulmonary Disease
Fu Y, Liu L, Wu H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1671-1683
Published Date: 27 July 2022


Supporting Behavior Change After AECOPD – Development of a Hospital-Initiated Intervention Using the Behavior Change Wheel
Schmid-Mohler G, Hübsch C, Steurer-Stey C, Greco N, Schuurmans MM, Beckmann S, Chadwick P, Clarenbach C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1651-1669
Published Date: 26 July 2022


Spatial Association of Environmental and Dietary Factors with COPD Deaths


Aktas S, Tuzuner B, Mergen M, Sultan-Ali I, Kocak M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1643-1650
Published Date: 26 July 2022

Single-Inhaler Triple Therapy in Patients with Advanced COPD: Bayesian Modeling of the Healthcare Resource Utilization Data and Associated Costs from the IMPACT Trial
Gabrio A, Gunsoy NB, Baio G, Martin A, Paly VF, Risebrough N, Halpin DMG, Singh D, Wise RA, Han MK, Martinez FJ, Criner GJ, Martin N, Lipson DA, Ismaila AS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1633-1642
Published Date: 25 July 2022

SMAD4 rs10502913 is Significantly Associated with Chronic Obstructive Pulmonary Disease in a Chinese Han Population: A Case-Control Study
Hou Z, Yuan Z, Wang H, Chang K, Gao Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1623-1631
Published Date: 19 July 2022

Evaluating the Relationship of Airflow Obstruction in COPD with Severity of OSA Among Patients with Overlap Syndrome
Stewart NH, Brittan M, McElligott M, Summers MO, Samson K, Press VG
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1613-1621
Published Date: 14 July 2022
Molecular and Clinicopathological Characteristics of Lung Cancer Concomitant Chronic Obstructive Pulmonary Disease (COPD)
Ma H, Zhang Q, Zhao Y, Zhang Y, Zhang J, Chen G, Tan Y, Zhang Q, Duan Q, Sun T, Qi C, Li F
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1601-1612
Published Date: 14 July 2022
Serum Derivatives of Reactive Oxygen Metabolites are Associated with Severity of Chronic Obstructive Pulmonary Disease and Affected by a p53 Gene Polymorphism
Yamamura K, Nojiri M, Nishiki K, Kato R, Shinomiya S, Takahara Y, Oikawa T, Ishizaki T, Toga H, Mizuno S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1589-1600
Published Date: 13 July 2022

Pulmonologists’ Opinion on the Use of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease Patients in Spain: A Cross-Sectional Survey
Miravitlles M, González-Torralba F, Represas-Represas C, Pomares X, Márquez-Martín E, González C, Amado C, Forné C, Alonso S, Alcázar B, Barrecheguren M, Jurado Mirete JM, Naval E
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1577-1587
Published Date: 12 July 2022

Pathological Mechanism and Targeted Drugs of COPD
Guo P, Li R, Piao TH, Wang CL, Wu XL, Cai HY
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1565-1575
Published Date: 12 July 2022
Relationship Between Episodic Nocturnal Hypercapnia and History of Exacerbations in Patients with Advanced Chronic Obstructive Pulmonary Disease
Kitajima T, Marumo S, Amimoto H, Shiraishi Y, Yamaki H, Shirata M, Inoue D, Fukui M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1553-1563
Published Date: 7 July 2022

Complex Evaluation of Surfactant Protein A and D as Biomarkers for the Severity of COPD
Lv MY, Qiang LX, Wang BC, Zhang YP, Li ZH, Li XS, Jin LL, Jin SD
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1537-1552
Published Date: 2 July 2022
Clinical Impact of Compensatory Hyperinflation of the Nontreated Adjacent Lobe After Bronchoscopic Lung Volume Reduction with Valves
Wienker J, Darwiche K, Wälscher J, Winantea J, Hagemann M, Büscher E, Singla A, Taube C, Karpf-Wissel R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1523-1536
Published Date: 1 July 2022

Qualitative Validation of COPD Evidenced Care Pathways in Japan, Canada, England, and Germany: Common Barriers to Optimal COPD Care
Meiwald A, Gara-Adams R, Rowlandson A, Ma Y, Watz H, Ichinose M, Scullion J, Wilkinson T, Bhutani M, Weston G, Adams EJ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1507-1521
Published Date: 1 July 2022
Respiratory Impedance is Associated with Ventilation and Diffusing Capacity in Patients with Idiopathic Pulmonary Fibrosis Combined with Emphysema
Yamamoto Y, Hirata H, Shiroyama T, Kuge T, Matsumoto K, Yoneda M, Yamamoto M, Naito Y, Suga Y, Fukushima K, Miyake K, Koyama S, Iwahori K, Nagatomo I, Takeda Y, Kumanogoh A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1495-1506
Published Date: 1 July 2022

Low Peak Inspiratory Flow Rates are Common Among COPD Inpatients and are Associated with Increased Healthcare Resource Utilization: A Retrospective Cohort Study
Clark B, Wells BJ, Saha AK, Franchino-Elder J, Shaikh A, Donato BMK, Ohar JA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1483-1494
Published Date: 29 June 2022
Differences in the Measurement of Functional Residual Capacity Between Body Plethysmographs of Two Manufacturers
Alter P, Orszag J, Wouters EF, Vogelmeier CF, Jörres RA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1477-1482
Published Date: 24 June 2022
Sex Differences in the International Primary Care Airways Group Questionnaire for Screening of Chronic Obstructive Pulmonary Disease: A Retrospective, Cross-Sectional Study
Machiguchi H, Arizono S, Tawara Y, Oomagari M, Yanagita Y, Tanaka T, Senjyu H, Kozu R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1467-1476
Published Date: 22 June 2022

Characteristics of New Users of Single- and Multiple-Inhaler Triple Therapy for COPD in Primary Care in England
Rothnie KJ, Joksaite S, Sansbury LB, Compton C, Di Boscio V, Ismaila AS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1455-1466
Published Date: 22 June 2022
The Therapeutic Index as Indicated by Efficacy/Safety Ratio May Be Primarily Assessed by Meta-Analysis of the Efficacy of ICS Combination Therapy for COPD [Letter]
Teramoto S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1453-1454
Published Date: 22 June 2022
Associations Between Morphological Phenotypes of COPD and Clinical Characteristics in Surgically Resected Patients with COPD and Concomitant Lung Cancer
Suzuki Y, Kitaguchi Y, Ueno F, Droma Y, Goto N, Kinjo T, Wada Y, Yasuo M, Hanaoka M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1443-1452
Published Date: 21 June 2022

A Social Return on Investment Analysis of Improving the Management of Chronic Obstructive Pulmonary Disease Within the Spanish National Healthcare System
Merino M, Martín Lorenzo T, Maravilla-Herrera P, Ancochea J, Gómez Sáenz JT, Hass N, Molina J, Peces-Barba G, Trapero-Bertran M, Trigueros Carrero JA, Hidalgo-Vega Á
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1431-1442
Published Date: 21 June 2022
Inhaled Steroids, Sex and Emphysema Index – Clinical Parameters with Impact on the Effectiveness of Valve Implantation in Patients with Severe Emphysema
Polke M, Brugger J, Rötting M, Polke N, Brock J, Schuler S, Richter I, Eberhardt R, Herth FJF, Gompelmann D
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1423-1430
Published Date: 20 June 2022

Treatment Patterns, Socioeconomic Status and Clinical Burden in Mild COPD: A Swedish Real-World, Retrospective Cohort Study, the ARCTIC Study
Larsson K, Lisspers K, Ställberg B, Johansson G, Gutzwiller FS, Mezzi K, Bjerregaard BK, Jorgensen L, Koo H, Janson C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1409-1421
Published Date: 21 June 2022

Association of Airway Eosinophilia with Small Airway Dysfunction in Patients with Mild and at Risk for COPD
Abdo M, Pedersen F, Trinkmann F, Herth FJF, Rabe KF, Kirsten AM, Watz H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1403-1408
Published Date: 17 June 2022
Triglyceride-Glucose Index is a Risk Marker of Incident COPD Events in Women
Zaigham S, Tanash H, Nilsson PM, Muhammad IF
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1393-1401
Published Date: 17 June 2022

Efficacy of a Self-Designed Questionnaire for Community Screening of COPD


Yang S, Yin X, Zhang Y, Zhao H, Zheng Z, Li J, Hu X, Xie J, Jie Z, Wang N, Shi J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1381-1391
Published Date: 14 June 2022

The Incidence and Prevalence of Pulmonary Hypertension in the COPD Population: A Systematic Review and Meta-Analysis
Zhang L, Liu Y, Zhao S, Wang Z, Zhang M, Zhang S, Wang X, Zhang S, Zhang W, Hao L, Jiao G
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1365-1379
Published Date: 10 June 2022

Characteristics of Patients with Chronic Obstructive Pulmonary Disease Treated with Long-Acting Bronchodilators in a Real-World Setting in Singapore: A Single-Center Observational Study
Sim M, Yii A, Xu X, Bahety P, Loh CH, Navarro Rojas AA, Milea D, Tee A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1349-1363
Published Date: 9 June 2022

IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease
Huang S, Feng T, Wang J, Dong L
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1339-1347
Published Date: 7 June 2022

Parental COPD as a Risk Factor for the Development of COPD and Disease Severity in Offspring: A Systematic Scoping Review
Sikjær MG, Klitgaard A, Hilberg O, Løkke A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1323-1338
Published Date: 8 June 2022

Hospital Cost Savings for Sequential COPD Patients Receiving Domiciliary Nasal High Flow Therapy
Milne RJ, Hockey HU, Garrett J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1311-1322
Published Date: 3 June 2022

Fibrinogen, a Promising Marker to Evaluate Severity and Prognosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Retrospective Observational Study
Sun W, Cao Z, Ma Y, Wang J, Zhang L, Luo Z
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1299-1310
Published Date: 3 June 2022

The Bufei Jianpi Formula Improves Mucosal Immune Function by Remodeling Gut Microbiota Through the SCFAs/GPR43/NLRP3 Pathway in Chronic Obstructive Pulmonary Disease Rats
Mao J, Li Y, Bian Q, Xuan Y, Li J, Wang Z, Feng S, Liu X, Tian Y, Li S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1285-1298
Published Date: 1 June 2022

Improving Physiological, Physical, and Psychological Health Outcomes: A Narrative Review in US Veterans with COPD
Bamonti PM, Robinson SA, Wan ES, Moy ML
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1269-1283
Published Date: 1 June 2022

Antibiotic Prescriptions in Hospitalized Patients with an Exacerbation COPD and a Proven Influenza or RS Virus Infection
van Brummelen S, Tramper-Stranders G, Jonkman K, de Boer G, in 't Veen J, Braunstahl GJ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1261-1267
Published Date: 1 June 2022

Development of Aging-Related Emphysematous and Lymphoma-Like Lesions is Enhanced by the Lack of Secretoglobin 3A2 in Mouse Lungs
Kurotani R, Kurumazuka A, Sakahara S, Takakura K, Yokoyama Y, Xu L, Dai J, Lee MP, Kumaki N, Abe H, Kimura S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1247-1260
Published Date: 26 May 2022

Hand Grip Strength and Likelihood of Moderate-to-Severe Airflow Limitation in the General Population
Kim S, Yoon HK, Rhee CK, Jung HW, Lee H, Jo YS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1237-1245
Published Date: 25 May 2022

Identification of Ferroptosis-Related Hub Genes and Their Association with Immune Infiltration in Chronic Obstructive Pulmonary Disease by Bioinformatics Analysis
Yang YC, Zhang MY, Liu JY, Jiang YY, Ji XL, Qu YQ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1219-1236
Published Date: 24 May 2022

Association between Inhaled β2-agonists Initiation and Risk of Major Adverse Cardiovascular Events: A Population-based Nested Case-Control Study
Amegadzie JE, Gamble JM, Farrell J, Gao Z
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1205-1217
Published Date: 20 May 2022

Associations Between Physical Activity, Smoking Status, and Airflow Obstruction and Self-Reported COPD: A Population-Based Study
Wu YK, Su WL, Yang MC, Chen SY, Wu CW, Lan CC
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1195-1204
Published Date: 20 May 2022

Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
Pournaras N, Andersson A, Kovach MA, Padra M, Che KF, Brundin B, Yoshihara S, Bozinovski S, Lindén SK, Jansson PA, Sköld MC, Qvarfordt I, Lindén A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1179-1194
Published Date: 20 May 2022


Prevalence of Chronic Obstructive Pulmonary Disease and Chronic Bronchitis Among Predominantly Smoking Workers in the Seafood Industry in Greenland
Frederiksen AL, Laustsen BH, Bælum J, Pedersen ML, Bønløkke JH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1167-1177
Published Date: 20 May 2022

The Main Pulmonary Artery to the Ascending Aorta Diameter Ratio (PA/A) as a Predictor of Worse Outcomes in Hospitalized Patients with AECOPD
Cheng Y, Li L, Tu X, Pei R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1157-1165
Published Date: 16 May 2022

Association Between Serum Sodium and Long-Term Mortality in Critically Ill Patients with Comorbid Chronic Obstructive Pulmonary Disease: Analysis from the MIMIC-IV Database
Fan L, Sun D, Yang J, Shi X, Shen F, Chen K, Yang J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1143-1155
Published Date: 12 May 2022

The Long-Term Maintenance Effect of Remote Pulmonary Rehabilitation via Social Media in COPD: A Randomized Controlled Trial
Li Y, Qian H, Yu K, Huang Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1131-1142
Published Date: 11 May 2022

Strain Analysis in Patients at High-Risk for COPD Using Four-Dimensional Dynamic-Ventilation CT
Xu Y, Liang T, Ma Y, Xie S, Sun H, Wang L, Xu Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1121-1130
Published Date: 7 May 2022

Barriers and Facilitators for Smoking Cessation in Chinese Smokers with Chronic Obstructive Pulmonary Disease: A Qualitative Study
Zhang YY, Tang WT, Zhang H, Wang J, Bai XX, Liao YH, Robinson N, Liu JP
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1107-1120
Published Date: 6 May 2022

Development of an Electronic Interdisciplinary Chronic Obstructive Pulmonary Disease (COPD) Proforma (E-ICP) to Improve Interdisciplinary Guideline Adherence in the Emergency Department: Modified Delphi Study
Issac H, Keijzers G, Yang IA, Lea J, Taylor M, Moloney C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1089-1106
Published Date: 6 May 2022

Where Do Chronic Obstructive Pulmonary Disease Patients Die? 8-Year Trend, with Special Focus on Sex-Related Differences
Fernández-García A, Pérez-Ríos M, Candal-Pedreira C, Represas-Represas C, Fernández-Villar A, Santiago-Pérez MI, Rey-Brandariz J, Naveira-Barbeito G, Malvar-Pintos A, Ruano-Ravina A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1081-1087
Published Date: 6 May 2022

Association Between Serum Uric Acid and Lung Function in People with and without Chronic Obstructive Pulmonary Disease
Yang H, Wang Z, Xiao S, Dai C, Wen X, Wu F, Peng J, Tian H, Zhou Y, Ran P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1069-1080
Published Date: 5 May 2022

Efficacy of ICS versus Non-ICS Combination Therapy in COPD: A Meta-Analysis of Randomised Controlled Trials
Ding Y, Sun L, Wang Y, Zhang J, Chen Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1051-1067
Published Date: 5 May 2022

Diaphragmatic Movement at Rest and After Exertion: A Non-Invasive and Easy to Obtain Prognostic Marker in COPD
Mekov E, Yanev N, Kurtelova N, Mihalova T, Tsakova A, Yamakova Y, Miravitlles M, Petkov R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1041-1050
Published Date: 5 May 2022

Association Between Serum Total Bilirubin Level and Lung Function Decline in Patients with COPD: Results from a Pooled Study
Dai C, Wang Z, Deng Z, Wu F, Yang H, Xiao S, Wen X, Zheng Y, Xu J, Lu L, Zhao N, Huang P, Zhou Y, Ran P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1031-1039
Published Date: 5 May 2022

Respiratory Oscillometry in Chronic Obstructive Pulmonary Disease: Association with Functional Capacity as Evaluated by Adl Glittre Test and Hand Grip Strength Test
Ribeiro CO, Lopes AJ, Melo PL
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1017-1030
Published Date: 4 May 2022

FIDEPOC: Consensus on Inspiratory Flow and Lung Deposition as Key Decision Factors in COPD Inhaled Therapy
González-Torralba F, Baloira A, Abad A, Fuster A, García-Rivero JL, García-Sidro P, Márquez-Martín E, Palop M, Soler N, Velasco JL
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1005-1015
Published Date: 4 May 2022

Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)
Lundh L, Larsson K, Lindén A, Montgomery S, Palmberg L, Sandelowsky H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:993-1004
Published Date: 2 May 2022

Ethical Dilemmas in Physicians’ Consultations with COPD Patients
Sigurgeirsdottir J, Halldorsdottir S, Arnardottir RH, Gudmundsson G, Bjornsson EH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:977-991
Published Date: 2 May 2022

Comparing Clinical Outcomes of Tiotropium/Olodaterol, Umeclidinium/Vilanterol, and Indacaterol/Glycopyrronium Fixed-Dose Combination Therapy in Patients with Chronic Obstructive Pulmonary Disease in Taiwan: A Multicenter Cohort Study
Hsieh MJ, Chen NH, Cheng SL, Tao CW, Wei YF, Wu YK, Chan MC, Liu SF, Hsu WH, Yang TM, Lin MS, Liu CL, Kuo PH, Tsai YH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:967-976
Published Date: 27 April 2022

Evaluating the Feasibility and Pretesting the Impact of an Educational and Telemonitoring Program for COPD Patients in Lebanon
Nohra RG, Chaaban T, Sacre H, Salameh P, Aoun Bacha Z, Le Bon Chami B, Abou Rizk F, Makhlouf P, Rothan-Tondeur M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:949-965
Published Date: 27 April 2022

Different Responses to Pulmonary Rehabilitation in COPD Patients with Different Work Efficiencies
Jao LY, Hsieh PC, Wu YK, Yang MC, Wu CW, Lee C, Tzeng IS, Lan CC
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:931-947
Published Date: 26 April 2022

CT-Based Commercial Software Applications: Improving Patient Care Through Accurate COPD Subtyping
Wang JM, Ram S, Labaki WW, Han MK, Galbán CJ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:919-930
Published Date: 26 April 2022

Evaluation of a Digital COPD Education Program for Healthcare Professionals in Long-Term Care – A Mixed Methods Study
Nyberg A, Lundell S, Pesola UM, Audulv, Wadell K
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:905-918
Published Date: 23 April 2022

Clinical and Psychological Impact of Chronic Pain in People with Chronic Obstructive Pulmonary Disease
Tanaka T, Okita M, Jenkins S, Kozu R
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:893-903
Published Date: 22 April 2022

The Impact of the Pay-for-Performance Program on the Outcome of COPD Patients in Taiwan After One Year
Cheng KC, Lai CC, Wang CY, Wang CM, Ho CH, Sung MI, Hsing SC, Liao KM, Ko SC
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:883-891
Published Date: 21 April 2022


Differences in the Spirometry Parameters Between Indigenous and Non-Indigenous Patients with COPD: A Matched Control Study
Sze DFL, Howarth TP, Lake CD, Ben Saad H, Heraganahally SS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:869-881
Published Date: 21 April 2022

The Relationship Between Comorbidities and Microbiologic Findings in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Seo H, Sim YS, Min KH, Lee JH, Kim BK, Oh YM, Ra SW, Kim TH, Hwang YI, Park JW
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:855-867
Published Date: 20 April 2022

Systematic Review of Physical Activity, Sedentary Behaviour and Sleep Among Adults Living with Chronic Respiratory Disease in Low- and Middle-Income Countries
Jayamaha AR, Jones AV, Katagira W, Girase B, Yusuf ZK, Pina I, Wilde LJ, Akylbekov A, Divall P, Singh SJ, Orme MW
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:821-854
Published Date: 18 April 2022

Factors Related with Hospital Attendance and Mortality in Patients with COPD: A Case–Control Study in a Real-Life Setting
López-Pardo ME, Candal-Pedreira C, Valdés-Cuadrado L, Represas-Represas C, Ruano-Ravina A, Pérez-Ríos M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:809-819
Published Date: 14 April 2022

Autophagy Induced by BCL2-Related ceRNA Network Participates in the Occurrence of COPD
Shi ZE, Zhang MY, Liu JY, Zhang WD, Hu DM, Wang QX, Ji XL, Jiang YY, Qu YQ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:791-808
Published Date: 8 April 2022

Serum Creatinine to Cystatin C Ratio is an Effective Indicator for Muscle Strength Decline in Men with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Huang D, Xie C, Sun C, Chen M, Li L, Yi H, Liao J, Zhao X, Shen X, He D, Li D, Wu D
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:781-789
Published Date: 8 April 2022

A Simple Scoring System to Differentiate Bacterial from Viral Infections in Acute Exacerbations of COPD Requiring Hospitalization
Ruiz-González A, Sáez-Huerta E, Martínez-Alonso M, Bernet-Sánchez A, Porcel JM
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:773-779
Published Date: 8 April 2022

“NEWS2” as an Objective Assessment of Hospitalised COPD Exacerbation Severity
Stone PW, Minelli C, Feary J, Roberts CM, Quint JK, Hurst JR
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:763-772
Published Date: 8 April 2022


Treatment Patterns for Chronic Obstructive Pulmonary Disease (COPD) in the United States: Results from an Observational Cross-Sectional Physician and Patient Survey
Mannino D, Siddall J, Small M, Haq A, Stiegler M, Bogart M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:749-761
Published Date: 6 April 2022

Evaluating Triple Therapy Treatment Pathways in Chronic Obstructive Pulmonary Disease (COPD): A Machine-Learning Predictive Model
Bogart M, Liu Y, Oakland T, Stiegler M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:735-747
Published Date: 6 April 2022

Baseline Level and Reduction in PaCO2 are Associated with the Treatment Effect of Long-Term Home Noninvasive Positive Pressure Ventilation in Stable Hypercapnic Patients with COPD: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Wu Z, Luo Z, Luo Z, Ge J, Jin J, Cao Z, Ma Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:719-733
Published Date: 6 April 2022

Frailty Among Older Individuals with and without COPD: A Cohort Study of Prevalence and Association with Adverse Outcomes
Roberts MH, Mapel DW, Ganvir N, Dodd MA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:701-717
Published Date: 5 April 2022

ZNF143 Expression is Associated with COPD and Tumor Microenvironment in Non-Small Cell Lung Cancer
Feng Z, Yin Y, Liu B, Wang L, Chen M, Zhu Y, Zhang H, Sun D, Qin J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:685-700
Published Date: 2 April 2022
Using Tools as Designed [Response to Letter]
Zhou J, Wang W
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:683-684
Published Date: 31 March 2022

NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema
Liu J, Zhang Z, Yang Y, Di T, Wu Y, Bian T
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:667-681
Published Date: 30 March 2022

Prohibitin Protects Pulmonary Microvascular Endothelial Cells Against Cigarette Smoke Extract-Induced Cell Apoptosis and Inflammation
Peng Y, Cheng W, Duan J, Zhao Y, Zhou Z, Zhou A, Deng M, Peng H, Ouyang R, Chen Y, Chen P
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:653-665
Published Date: 29 March 2022

Improving the Reliability Between the BODE Index and the BODS Index in Which the 6-Min Walk Test Was Replaced with the Five-Repetition Sit-to-Stand Test
Bernabeu-Mora R, Valera-Novella E, Sánchez-Martínez MP, Medina-Mirapeix F
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:643-652
Published Date: 29 March 2022

Developing Appropriate Pulmonary Rehabilitation Services in Sri Lanka: Assessment of People Living with COPD and Healthcare Providers in Urban and Semi Urban Areas in Sri Lanka
Perera ACH, Jayamaha AR, Jones AV, Yusuf ZK, Wijayasiri KDCU, Amarasekara T, Seneviratne A, Miah R, Barton A, Steiner MC, Wimalasekara SW, Orme MW, Singh SJ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:631-641
Published Date: 25 March 2022

The Impact of Chronic Bronchial Infection in COPD: A Proposal for Management
Martinez-Garcia MA, Miravitlles M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:621-630
Published Date: 23 March 2022
Cost-Effectiveness of Umeclidinium/Vilanterol versus Salmeterol/Fluticasone in Elderly Patients with Chronic Obstructive Pulmonary Diseases in China
Lan Y, Yang N, Wang Y, Yang Y, Xu M, He Q
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:609-619
Published Date: 22 March 2022

Relationship of COPD Exacerbation Severity and Frequency on Risks for Future Events and Economic Burden in the Medicare Fee-For-Service Population
Sethi S, Make BJ, Robinson SB, Kumar S, Pollack M, Moretz C, Dreyfus J, Xi A, Powell D, Feigler N
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:593-608
Published Date: 20 March 2022

Using Tools as Designed [Letter]
Han M, Make B, Yawn BP
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:591-592
Published Date: 18 March 2022

Association Between Vitamin D Level and Respiratory Symptoms in Patients with Stable Chronic Obstructive Pulmonary Disease
Lee CY, Shin SH, Choi HS, Im Y, Kim BG, Song JY, Lee D, Park HY, Lim JH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:579-590
Published Date: 17 March 2022

Disease Trajectories and Impact of One Moderate Exacerbation in Gold B COPD Patients
Løkke A, Hilberg O, Lange P, Ibsen R, Stratelis G, de Fine Licht S, Lykkegaard J
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:569-578
Published Date: 16 March 2022

Prospective Evaluation of Exacerbations Associated with Suboptimal Peak Inspiratory Flow Among Stable Outpatients with COPD
Mahler DA, Niu X, Deering KL, Dembek C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:559-568
Published Date: 15 March 2022


A Pooled Analysis of Mortality in Patients with COPD Receiving Dual Bronchodilation with and without Additional Inhaled Corticosteroid

Miravitlles M, Verhamme K, Calverley PMA, Dreher M, Bayer V, Gardev A, de la Hoz A, Wedzicha J, Price D
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:545-558
Published Date: 11 March 2022

Impact of Coexisting Dementia on Inpatient Outcomes for Patients Admitted with a COPD Exacerbation
Gupta A, McKeever TM, Hutchinson JP, Bolton CE
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:535-544
Published Date: 10 March 2022

Differential Outcomes Following 4 Weeks of Aclidinium/Formoterol in Patients with COPD: A Reanalysis of the ACTIVATE Study
Koopman M, Franssen FME, Gaffron S, Watz H, Troosters T, Garcia-Aymerich J, Paggiaro P, Molins E, Moya M, van Burk L, Maier D, Garcia Gil E, Wouters EFM, Vanfleteren LEGW, Spruit MA
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:517-533
Published Date: 8 March 2022

Different Smoking Statuses on Survival and Emphysema in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Ding Q, Li J, Xu S, Gao Y, Guo Y, Xie B, Li H, Wei X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:505-515
Published Date: 5 March 2022

Benefit of Prompt versus Delayed Use of Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Following a COPD Exacerbation
Mannino D, Bogart M, Germain G, Huang SP, Ismaila AS, Laliberté F, Jung Y, MacKnight SD, Stiegler MA, Duh MS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:491-504
Published Date: 5 March 2022

Interclass Difference in Pneumonia Risk in COPD Patients Initiating Fixed Dose Inhaled Treatment Containing Extrafine Particle Beclometasone versus Fine Particle Fluticasone [Corrigendum]
Price DB, Henley W, Cançado JED, Fabbri LM, Kerstjens HA, Papi A, Roche N, Şen E, Singh D, Vogelmeier CF, Barille S, Nudo E, Carter V, Skinner D, Vella R, Georges G
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:489-490
Published Date: 7 March 2022

Identification of Dysregulated Mechanisms and Candidate Gene Markers in Chronic Obstructive Pulmonary Disease
Lin J, Xue Y, Su W, Zhang Z, Wei Q, Huang T
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:475-487
Published Date: 4 March 2022

Assessments and Targeted Rehabilitation Therapies for Diaphragmatic Dysfunction in Patients with Chronic Obstructive Pulmonary Disease: A Narrative Review
Chen Y, Li P, Wang J, Wu W, Liu X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:457-473
Published Date: 3 March 2022

Identification of Hub Genes Associated with COPD Through Integrated Bioinformatics Analysis
Chen L, Zhu D, Huang J, Zhang H, Zhou G, Zhong X
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:439-456
Published Date: 3 March 2022

Frequency and Severity of Exacerbations of COPD Associated with Future Risk of Exacerbations and Mortality: A UK Routine Health Care Data Study
Whittaker H, Rubino A, Müllerová H, Morris T, Varghese P, Xu Y, De Nigris E, Quint JK
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:427-437
Published Date: 3 March 2022

Disease Burden and Healthcare Utilization Among Patients with Chronic Obstructive Pulmonary Disease (COPD) in England
Sansbury LB, Lipson DA, Bains C, Anley GA, Rothnie KJ, Ismaila AS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:415-426
Published Date: 3 March 2022

Respiratory Effects of Treatment with a Glucagon-Like Peptide-1 Receptor Agonist in Patients Suffering from Obesity and Chronic Obstructive Pulmonary Disease
Altintas Dogan AD, Hilberg O, Hess S, Jensen TT, Bladbjerg EM, Juhl CB
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:405-414
Published Date: 22 February 2022

Circulating Complement C1q as a Novel Biomarker is Associated with the Occurrence and Development of COPD
Zhang K, Han K, Liu H, Zheng C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:395-404
Published Date: 23 February 2022

Associations with Post-Consultation Health-Status in Primary Care Managed Acute Exacerbation of COPD
Gillespie D, Francis N, Ahmed H, Hood K, Llor C, White P, Thomas-Jones E, Stanton H, Sewell B, Phillips R, Naik G, Melbye H, Lowe R, Kirby N, Cochrane A, Bates J, Alam MF, Butler C
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:383-394
Published Date: 16 February 2022

Long-Term Risk of Mortality Associated with Isolation of Pseudomonas aeruginosa in COPD: A Systematic Review and Meta-Analysis
Martinez-García MA, Rigau D, Barrecheguren M, García-Ortega A, Nuñez A, Oscullo Yepez G, Miravitlles M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:371-382
Published Date: 16 February 2022

Interclass Difference in Pneumonia Risk in COPD Patients Initiating Fixed Dose Inhaled Treatment Containing Extrafine Particle Beclometasone versus Fine Particle Fluticasone
Price DB, Henley W, Cançado JED, Fabbri LM, Kerstjens HA, Papi A, Roche N, Şen E, Singh D, Vogelmeier CF, Barille S, Nudo E, Carter V, Skinner D, Vella R, Georges G
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:355-370
Published Date: 15 February 2022

TRPV4 Inhibition Exerts Protective Effects Against Resistive Breathing Induced Lung Injury
Toumpanakis D, Chatzianastasiou A, Vassilakopoulou V, Mizi E, Dettoraki M, Perlikos F, Giatra G, Mikos N, Theocharis S, Vassilakopoulos T
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:343-353
Published Date: 15 February 2022

PRIMUS – Prompt Initiation of Maintenance Therapy in the US: A Real-World Analysis of Clinical and Economic Outcomes Among Patients Initiating Triple Therapy Following a COPD Exacerbation
Tkacz J, Evans KA, Touchette DR, Portillo E, Strange C, Staresinic A, Feigler N, Patel S, Pollack M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:329-342
Published Date: 10 February 2022

Accuracy of Six Chronic Obstructive Pulmonary Disease Screening Questionnaires in the Chinese Population
Zhou J, Yu N, Li X, Wang W
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:317-327
Published Date: 10 February 2022

Sexual Health in COPD: A Systematic Review and Meta-Analysis
Farver-Vestergaard I, Frederiksen Y, Zachariae R, Rubio-Rask S, Løkke A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:297-315
Published Date: 9 February 2022

Pioglitazone and Risk of Chronic Obstructive Pulmonary Disease in Patients with Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Tseng CH
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:285-295
Published Date: 9 February 2022

Annual Body Weight Change and Prognosis in Chronic Obstructive Pulmonary Disease [Corrigendum]
Abe Y, Suzuki M, Shima H, Shiraishi Y, Tanabe N, Sato S, Shimizu K, Kimura H, Makita H, Hirai T, Konno S, Nishimura M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:283-284
Published Date: 8 February 2022

Blood Eosinophils in Chinese COPD Participants and Response to Treatment with Combination Low-Dose Theophylline and Prednisone: A Post-Hoc Analysis of the TASCS Trial
Bradbury T, Di Tanna GL, Scaria A, Martin A, Wen FQ, Zhong NS, Zheng JP, Barnes PJ, Celli B, Berend N, Jenkins CR
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:273-282
Published Date: 5 February 2022

Challenges and Strategies for Improving COPD Primary Care Services in Quebec: Results of the Experience of the COMPAS+ Quality Improvement Collaborative
Vachon B, Giasson G, Gaboury I, Gaid D, Noël De Tilly V, Houle L, Bourbeau J, Pomey MP
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:259-272
Published Date: 2 February 2022

Inhaled Corticosteroid Use Among COPD Patients in Primary Care in Spain
Miravitlles M, Roman-Rodríguez M, Ribera X, Ritz J, Izquierdo JL
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:245-258
Published Date: 25 January 2022

The Importance of Self-Management in the Context of Personalized Care in COPD
Cravo A, Attar D, Freeman D, Holmes S, Ip L, Singh SJ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:231-243
Published Date: 22 January 2022

Linguistic Validation of the Japanese Version of the Multidimensional Dyspnea Profile and Relation to Physical Activity in Patients with COPD
Kanezaki M, Tamaki A, Terada K, Ebihara S
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:223-230
Published Date: 21 January 2022


The Development of a COPD Exacerbation Recognition Tool (CERT) to Help Patients Recognize When to Seek Medical Advice


Jones PW, Wang C, Chen P, Chen L, Wang D, Xia J, Yang Y, Wang Y, Ma Q
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:213-222
Published Date: 21 January 2022

Long-Term Effect of Noninvasive Ventilation on Diaphragm in Chronic Respiratory Failure
Hernandez-Voth A, Sayas Catalan J, Corral Blanco M, Alonso Moralejo R, Perez Gonzalez V, De Pablo Gafas A, Castaño Menendez Menendez A, Juarros Monteagudo L, Villena Garrido V
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:205-212
Published Date: 18 January 2022

Obstructive Sleep Apnea is Associated with an Increased Prevalence of Polycythemia in Patients with Chronic Obstructive Pulmonary Disease
Zeng Z, Song Y, He X, Yang H, Yue F, Xiong M, Hu K
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:195-204
Published Date: 15 January 2022

Stable Chronic Obstructive Pulmonary Disease (COPD) Management Under a Tiered Medical System in China
Mao R, Liu Z, Zhao Y, Du C, Zhou J, Wang Q, Lu J, Gao L, Cui B, Ma Y, Sun T, Zhu L, Chen Z
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:181-194
Published Date: 14 January 2022

Beyond Dual Bronchodilation – Triple Therapy, When and Why
Cazzola M, Rogliani P, Laitano R, Calzetta L, Matera MG
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:165-180
Published Date: 14 January 2022

Does the Efficacy of High Intensity Ventilation in Stable COPD Depend on the Ventilator Model? A Bench-to-Bedside Study
Lalmolda C, Flórez P, Corral M, Hernández Voth A, Grimau C, Sayas J, Luján M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:155-164
Published Date: 14 January 2022

Barriers and Enablers to Pulmonary Rehabilitation in Low- and Middle-Income Countries: A Qualitative Study of Healthcare Professionals
Bickton FM, Shannon H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:141-153
Published Date: 13 January 2022

Cigarette Smoke Particle-Induced Lung Injury and Iron Homeostasis
Ghio AJ, Pavlisko EN, Roggli VL, Todd NW, Sangani RG
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:117-140
Published Date: 12 January 2022

SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD – Possible Implications for Interstitial Fibrosis
Brake SJ, Eapen MS, McAlinden KD, Markos J, Haug G, Larby J, Chia C, Hardikar A, Singhera GK, Hackett TL, Lu W, Sohal SS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:101-115
Published Date: 11 January 2022

DKK1 Positively Correlates with Lung Function in COPD Patients and Reduces Airway Inflammation
Dai L, Xu D, Wan C, Liu L, Wen F
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:93-100
Published Date: 6 January 2022


Measuring Peak Inspiratory Flow in Patients with Chronic Obstructive Pulmonary Disease
Ohar JA, Ferguson GT, Mahler DA, Drummond MB, Dhand R, Pleasants RA, Anzueto A, Halpin DMG, Price DB, Drescher GS, Hoy HM, Haughney J, Hess MW, Usmani OS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:79-92
Published Date: 6 January 2022

Effect of Smoking and Its Cessation on the Transcript Profile of Peripheral Monocytes in COPD Patients
Trivedi A, Bade G, Madan K, Bhat MA, Guleria R, Talwar A
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:65-77
Published Date: 5 January 2022

Opinions and Attitudes of Pulmonologists About Augmentation Therapy in Patients with Alpha-1 Antitrypsin Deficiency. A Survey of the EARCO Group
Greulich T, Albert A, Cassel W, Boeselt T, Peychev E, Klemmer A, Ferreira F, Clarenbach C, Torres-Duran ML, Turner AM, Miravitlles M
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:53-64
Published Date: 5 January 2022

The Clinical Course of Severe Alpha-1-Antitrypsin Deficiency in Patients Identified by Screening
Hiller AM, Piitulainen E, Tanash H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:43-52
Published Date: 5 January 2022

Moderate Treadmill Training Induces Limited Effects on Quadriceps Muscle Hypertrophy in Mice Exposed to Cigarette Smoke Involving Metalloproteinase 2
Vieira Ramos G, Sousa Neto IV, Toledo-Arruda AC, Marqueti RC, Vieira RP, Martins MA, Salvini TF, Durigan JLQ
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:33-42
Published Date: 6 January 2022

Predictors of Influenza PCR Positivity in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Chen CYJ, Yew MS, Abisheganaden JA, Xu H
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:25-32
Published Date: 6 January 2022

Identification of the Key Immune-Related Genes in Chronic Obstructive Pulmonary Disease Based on Immune Infiltration Analysis
Meng H, Long Q, Wang R, Zhou X, Su H, Wang T, Li Y
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:13-24
Published Date: 4 January 2022

Diaphragm Ultrasound is an Imaging Biomarker that Distinguishes Exacerbation Status from Stable Chronic Obstructive Pulmonary Disease
An TJ, Yoo YJ, Lim JU, Seo W, Park CK, Rhee CK, Yoon HK
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:3-12
Published Date: 4 January 2022
Image-Enhanced Bronchoscopic Evaluation of Bronchial Mucosal Microvasculature in COPD [Corrigendum]
Metwally EM, Shafiek H, Morsi T, El Sabaa B, Elnekidy A, Elhoffy M, Atta MS
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:1-2
Published Date: 5 January 2022