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Drug Design, Development and Therapy
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Archive: Volume 15, 2021
Bitter Taste Receptor as a Therapeutic Target in Orthopaedic Disorders
Cheng W, Yao M, Liu F
Drug Design, Development and Therapy 2021, 15:895-903
Published Date: 26 February 2021
Low Frequency of Integrase Inhibitor Resistance Mutations Among Therapy-Naïve HIV Patients in Southeast China
Lai J, Liu Y, Han X, Huang A, Lin J, Ao W, Ye H, Chen Y
Drug Design, Development and Therapy 2021, 15:889-894
Published Date: 26 February 2021
Taxifolin, Extracted from Waste Larix olgensis Roots, Attenuates CCl4-Induced Liver Fibrosis by Regulating the PI3K/AKT/mTOR and TGF-β1/Smads Signaling Pathways
Liu X, Liu W, Ding C, Zhao Y, Chen X, Ling D, Zheng Y, Cheng Z
Drug Design, Development and Therapy 2021, 15:871-887
Published Date: 26 February 2021
Aloperine Inhibits Proliferation and Promotes Apoptosis in Colorectal Cancer Cells by Regulating the circNSUN2/miR-296-5p/STAT3 Pathway
Han W, Kong D, Lu Q, Zhang W, Fan Z
Drug Design, Development and Therapy 2021, 15:857-870
Published Date: 25 February 2021
Breviscapine Pretreatment Inhibits Myocardial Inflammation and Apoptosis in Rats After Coronary Microembolization by Activating the PI3K/Akt/GSK-3β Signaling Pathway
Chen ZQ, Zhou Y, Chen F, Huang JW, Zheng J, Li HL, Li T, Li L
Drug Design, Development and Therapy 2021, 15:843-855
Published Date: 25 February 2021
Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations
Wang J, Liu L, Song Y, Jiao J, Zhong Y
Drug Design, Development and Therapy 2021, 15:835-842
Published Date: 25 February 2021
Effects of Sugammadex versus Neostigmine on Intraoperative Coagulation Profiles in Patients with Thyroidectomy
Zhao D, Fang J, Xiong W, Lin J, Chen W, Wu C
Drug Design, Development and Therapy 2021, 15:829-834
Published Date: 25 February 2021
Predicting and Exploring the Mechanisms of Erzhi Pill in Prevention and Treatment of Osteoporosis Based on Network Pharmacology and Zebrafish Experiments
Zhong Z, Li Y, Chen Y, Chen W, Li S, Lv X, Luo S
Drug Design, Development and Therapy 2021, 15:817-827
Published Date: 24 February 2021
Efficacy and Safety of Retinol Palmitate Ophthalmic Solution in the Treatment of Dry Eye: A Japanese Phase II Clinical Trial [Corrigendum]
Toshida H, Funaki T, Ono K, Tabuchi N, Watanabe S, Seki T, Otake H, Kato T, Ebihara N, Murakami A
Drug Design, Development and Therapy 2021, 15:813-816
Published Date: 24 February 2021
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin αvβ5 Signaling Pathway
Zhang Y, Shi X, Han J, Peng W, Fang Z, Zhou Y, Xu X, Lin J, Xiao F, Zhao L, Lin Y
Drug Design, Development and Therapy 2021, 15:803-812
Published Date: 23 February 2021
Dopamine-Mediated Vanillin Multicomponent Derivative Synthesis via Grindstone Method: Application of Antioxidant, Anti-Tyrosinase, and Cytotoxic Activities
Mani A, Ahamed A, Ali D, Alarifi S, Akbar I
Drug Design, Development and Therapy 2021, 15:787-802
Published Date: 23 February 2021
The Volatile Oil of Zanthoxylum bungeanum Pericarp Improved the Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota to Attenuate Chronic Unpredictable Stress-Induced Anxiety Behavior in Rats
Wei D, Zhao Y, Zhang M, Zhu L, Wang L, Yuan X, Wu C
Drug Design, Development and Therapy 2021, 15:769-786
Published Date: 22 February 2021
Mechanism of Action of Xiaoyao San in Treatment of Ischemic Stroke is Related to Anti-Apoptosis and Activation of PI3K/Akt Pathway
Xu Y, Chen W, Chen Z, Huang M, Yang F, Zhang Y
Drug Design, Development and Therapy 2021, 15:753-767
Published Date: 22 February 2021
The Effectiveness of Ruxolitinib for Acute/Chronic Graft-versus-Host Disease in Children: A Retrospective Study
Yang W, Zhu G, Qin M, Li Z, Wang B, Yang J, Wang T
Drug Design, Development and Therapy 2021, 15:743-752
Published Date: 22 February 2021
Addition of Celebrex and Pregabalin to Ropivacaine for Posterior Spinal Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial
Zhang Y, He B, Zhao J, Zhang M, Ren Q, Zhang W, Xu S, Quan Z, Ou Y
Drug Design, Development and Therapy 2021, 15:735-742
Published Date: 22 February 2021
The Risks of miRNA Therapeutics: In a Drug Target Perspective
Zhang S, Cheng Z, Wang Y, Han T
Drug Design, Development and Therapy 2021, 15:721-733
Published Date: 22 February 2021
Danggui Buxue Decoction in the Treatment of Metastatic Colon Cancer: Network Pharmacology Analysis and Experimental Validation
Feng SH, Zhao B, Zhan X, Motanyane R, Wang SM, Li A
Drug Design, Development and Therapy 2021, 15:705-720
Published Date: 24 February 2021
Glucocorticoid-Like Activity of Escin: A New Mechanism for an Old Drug
Gallelli L, Cione E, Wang T, Zhang L
Drug Design, Development and Therapy 2021, 15:699-704
Published Date: 24 February 2021
The Effectiveness and Safety of Intravenous Dexmedetomidine of Different Concentrations Combined with Butorphanol for Post-Caesarean Section Analgesia: A Randomized Controlled Trial
Liu S, Peng P, Hu Y, Liu C, Cao X, Yang C, Gao M
Drug Design, Development and Therapy 2021, 15:689-698
Published Date: 18 February 2021
Trans-Cinnamaldehyde Increases Random Pattern Flap Survival Through Activation of the Nitric Oxide Pathway
Luo X, Zhao B, Chen B, Chen H, Han T, Bsoul NBN, Yan H
Drug Design, Development and Therapy 2021, 15:679-688
Published Date: 18 February 2021
Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study
Gomha SM, Abdelhady HA, Hassain DZH, Abdelmonsef AH, El-Naggar M, Elaasser MM, Mahmoud HK
Drug Design, Development and Therapy 2021, 15:659-677
Published Date: 17 February 2021
Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study
Yang E, Yoo H, Jang IJ, Yu KS, Lee S
Drug Design, Development and Therapy 2021, 15:651-658
Published Date: 17 February 2021
Progress in Clinical Research on Gonadotropin-Releasing Hormone Receptor Antagonists for the Treatment of Prostate Cancer
Liu YF, Fu SQ, Yan YC, Gong BB, Xie WJ, Yang XR, Sun T, Ma M
Drug Design, Development and Therapy 2021, 15:639-649
Published Date: 16 February 2021
Safety, Tolerability, and Pharmacokinetics of Ibuprofenamine Hydrochloride Spray (NSAIDs), a New Drug for Rheumatoid Arthritis and Osteoarthritis, in Healthy Chinese Subjects
Xie P, Xue W, Qi W, Li Y, Yang L, Yang Z, Shi A
Drug Design, Development and Therapy 2021, 15:629-638
Published Date: 16 February 2021
Treatment of Severe Acute Bacterial Keratitis in Rabbits Using Continuous Topical Ocular Instillation with Norvancomycin
Lin W, Zhao L, Tan Q, Lin D
Drug Design, Development and Therapy 2021, 15:617-628
Published Date: 16 February 2021
Effect of Different Dosage Frequency of Polymyxin B on Rat Nephrotoxicity
Sun W, Hu B, Zhang X, Wang Y, Xiang Z, Lin G
Drug Design, Development and Therapy 2021, 15:611-616
Published Date: 16 February 2021
Preparation, Characterization and in vitro/in vivo Evaluation of Lovastatin-Loaded PLGA Microspheres by Local Administration for Femoral Head Necrosis
Sun Y, Long D
Drug Design, Development and Therapy 2021, 15:601-610
Published Date: 16 February 2021
Nephroprotective Effect of Adropinin Against Streptozotocin-Induced Diabetic Nephropathy in Rats: Inflammatory Mechanism and YAP/TAZ Factor
Guo L, Jiang B, Li D, Xiao X
Drug Design, Development and Therapy 2021, 15:589-600
Published Date: 16 February 2021
Effects of Quercetin on the Efficacy of Various Chemotherapeutic Drugs in Cervical Cancer Cells
Xu W, Xie S, Chen X, Pan S, Qian H, Zhu X
Drug Design, Development and Therapy 2021, 15:577-588
Published Date: 15 February 2021
Self-Nanoemulsifying Drug Delivery System of Genkwanin: A Novel Approach for Anti-Colitis-Associated Colorectal Cancer
Yin HF, Yin CM, Ouyang T, Sun SD, Chen WG, Yang XL, He X, Zhang CF
Drug Design, Development and Therapy 2021, 15:557-576
Published Date: 12 February 2021
Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway
Zheng B, Yang Y, Li J, Li J, Zuo S, Chu X, Xu S, Ma D, Chu L
Drug Design, Development and Therapy 2021, 15:543-556
Published Date: 12 February 2021
Synergistic Anticancer Strategy of Sonodynamic Therapy Combined with PI-103 Against Hepatocellular Carcinoma
Yang H, Jing H, Han X, Tan H, Cheng W
Drug Design, Development and Therapy 2021, 15:531-542
Published Date: 11 February 2021
L-Cysteine Provides Neuroprotection of Hypoxia-Ischemia Injury in Neonatal Mice via a PI3K/Akt-Dependent Mechanism
Li T, Li J, Li T, Zhao Y, Ke H, Wang S, Liu D, Wang Z
Drug Design, Development and Therapy 2021, 15:517-529
Published Date: 11 February 2021
Budesonide/Formoterol Anti-Inflammatory Reliever and Maintenance or Fluticasone Propionate/Salmeterol Plus as-Needed, Short-Acting β2 Agonist: Real-World Effectiveness in patients Without Optimally Controlled asthma (REACT) Study [Corrigendum]
Cheng SL, Ho ML, Lai YF, Wang HC, Hsu JY, Liu SF, Huang MS, Lee CH, Lin CH, Hang LW, Liu YC, Yang KY, Wang JH
Drug Design, Development and Therapy 2021, 15:515-516
Published Date: 12 February 2021
Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways
Zhang J, Wang C, Kang K, Liu H, Liu X, Jia X, Yu K
Drug Design, Development and Therapy 2021, 15:501-513
Published Date: 11 February 2021
EGCG Regulates Cell Apoptosis of Human Umbilical Vein Endothelial Cells Grown on 316L Stainless Steel for Stent Implantation
Wang J, Wang Y, Zhao Y, Zhao J, Zhang B, Xu K
Drug Design, Development and Therapy 2021, 15:493-499
Published Date: 11 February 2021
Long Noncoding RNA SOX2-OT Aggravates Doxorubicin-Induced Apoptosis of Cardiomyocyte by Targeting miR-942-5p/DP5
Wang H, Lin X, Li J, Zeng G, Xu T
Drug Design, Development and Therapy 2021, 15:481-492
Published Date: 11 February 2021
Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous Determination of Antipsychotic Drugs in Human Plasma and Its Application in Therapeutic Drug Monitoring
Qi Y, Liu G
Drug Design, Development and Therapy 2021, 15:463-479
Published Date: 12 February 2021
Profile of Enfortumab Vedotin in the Treatment of Urothelial Carcinoma: The Evidence to Date
Moussa M, Papatsoris A, Abou Chakra M, Dellis A
Drug Design, Development and Therapy 2021, 15:453-462
Published Date: 11 February 2021
Effect of Evodiamine on Rat Colonic Hypermotility Induced by Water Avoidance Stress and the Underlying Mechanism
Ren H, Yuan F, Tan W, Ding Y, An P, Luo H
Drug Design, Development and Therapy 2021, 15:441-452
Published Date: 10 February 2021
Zafirlukast in Combination with Pseudohypericin Attenuates Spinal Cord Injury and Motor Function in Experimental Mice [Corrigendum]
Chen XG, Hua F, Wang SG, Xu YY, Yue HT, Sun J
Drug Design, Development and Therapy 2021, 15:419-422
Published Date: 9 February 2021
Development and Characterization of PLGA Nanoparticle-Laden Hydrogels for Sustained Ocular Delivery of Norfloxacin in the Treatment of Pseudomonas Keratitis: An Experimental Study
Gebreel RM, Edris NA, Elmofty HM, Tadros MI, El-Nabarawi MA, Hassan DH
Drug Design, Development and Therapy 2021, 15:399-418
Published Date: 5 February 2021
Design, Synthesis, Molecular Modelling, and Biological Evaluation of Oleanolic Acid-Arylidene Derivatives as Potential Anti-Inflammatory Agents
Hassan Mir R, Godavari G, Siddiqui NA, Ahmad B, Mothana RA, Ullah R, Almarfadi OM, Jachak SM, Masoodi MH
Drug Design, Development and Therapy 2021, 15:385-397
Published Date: 4 February 2021
Thiazolidine Derivatives Attenuate Carrageenan-Induced Inflammatory Pain in Mice
Malik Z, Abbas M, Al Kury LT, Shah FA, Alam M, Khan AU, Nadeem H, Alghamdi S, Sahibzada MUK, Li S
Drug Design, Development and Therapy 2021, 15:369-384
Published Date: 4 February 2021
Irisin Protects Against Hind Limb Ischemia Reperfusion Injury
Küçük A, Polat Y, Kılıçarslan A, Süngü N, Kartal H, Dursun AD, Arslan M
Drug Design, Development and Therapy 2021, 15:361-368
Published Date: 4 February 2021
New Approach in Ocular Drug Delivery: In vitro and ex vivo Investigation of Cyclodextrin-Containing, Mucoadhesive Eye Drop Formulations
Bíró T, Bocsik A, Jurišić Dukovski B, Gróf I, Lovrić J, Csóka I, Deli MA, Aigner Z
Drug Design, Development and Therapy 2021, 15:351-360
Published Date: 3 February 2021
Therapeutic Effects of Modified Gengnianchun Formula on Stress-Induced Diminished Ovarian Reserve Based on Experimental Approaches and Network Pharmacology [Erratum]
Gao L, Zhang Y, Xu H, Zhao F, Wang W
Drug Design, Development and Therapy 2021, 15:349-350
Published Date: 27 January 2021
A Retrospective Observational Study of Anlotinib in Patients with Platinum-Resistant or Platinum-Refractory Epithelial Ovarian Cancer
Cui Q, Hu Y, Ma D, Liu H
Drug Design, Development and Therapy 2021, 15:339-347
Published Date: 27 January 2021
Tezepelumab as an Emerging Therapeutic Option for the Treatment of Severe Asthma: Evidence to Date
Dorey-Stein ZL, Shenoy KV
Drug Design, Development and Therapy 2021, 15:331-338
Published Date: 27 January 2021
CircNRIP1 Modulates the miR-515-5p/IL-25 Axis to Control 5-Fu and Cisplatin Resistance in Nasopharyngeal Carcinoma
Lin J, Qin H, Han Y, Li X, Zhao Y, Zhai G
Drug Design, Development and Therapy 2021, 15:323-330
Published Date: 27 January 2021
Administration of Dexmedetomidine Does Not Produce Long-Term Protective Effect on Testicular Damage Post Testicular Ischemia-Reperfusion Injury
Xiao J, Wan W, Zhang Y, Ma J, Yan L, Luo Y, Tang J
Drug Design, Development and Therapy 2021, 15:315-321
Published Date: 27 January 2021
Phenotyping Study of Cyclophosphamide 4-Hydroxylation in Malay Cancer Patients
Fityatal Hasanah YI, Harahap Y, Purwanto DJ
Drug Design, Development and Therapy 2021, 15:305-313
Published Date: 26 January 2021
Gypenosides Inhibit Inflammatory Response and Apoptosis of Endothelial and Epithelial Cells in LPS-Induced ALI: A Study Based on Bioinformatic Analysis and in vivo/vitro Experiments
Tu Q, Zhu Y, Yuan Y, Guo L, Liu L, Yao L, Zou Y, Li J, Chen F
Drug Design, Development and Therapy 2021, 15:289-303
Published Date: 25 January 2021
Physcion Protects Rats Against Cerebral Ischemia-Reperfusion Injury via Inhibition of TLR4/NF-kB Signaling Pathway
Dong X, Wang L, Song G, Cai X, Wang W, Chen J, Wang G
Drug Design, Development and Therapy 2021, 15:277-287
Published Date: 25 January 2021
Effects of Caffeic Acid and Its Derivatives on Bone: A Systematic Review
Ekeuku SO, Pang KL, Chin KY
Drug Design, Development and Therapy 2021, 15:259-275
Published Date: 22 January 2021
Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA-15b via the FOXO1/CCND1/β-Catenin Axis
Wang Y, Wang Q, Li X, Luo G, Shen M, Shi J, Wang X, Tang L
Drug Design, Development and Therapy 2021, 15:245-257
Published Date: 22 January 2021
Gracillin Isolated from Reineckia carnea Induces Apoptosis of A549 Cells via the Mitochondrial Pathway
Yang J, Cao L, Li Y, Liu H, Zhang M, Ma H, Wang B, Yuan X, Liu Q
Drug Design, Development and Therapy 2021, 15:233-243
Published Date: 20 January 2021
Galangin Improved Non-Alcoholic Fatty Liver Disease in Mice by Promoting Autophagy [Corrigendum]
Zhang X, Deng Y, Xiang J, Liu H, Zhang J, Liao J, Chen K, Liu B, Liu J, Pu Y
Drug Design, Development and Therapy 2021, 15:231-232
Published Date: 20 January 2021
Clinical Significance of Continuable Treatment with Nintedanib Over 12 Months for Idiopathic Pulmonary Fibrosis in a Real-World Setting
Kato M, Sasaki S, Tateyama M, Arai Y, Motomura H, Sumiyoshi I, Ochi Y, Watanabe J, Ihara H, Togo S, Takahashi K
Drug Design, Development and Therapy 2021, 15:223-230
Published Date: 18 January 2021
H2O2-Inactivated Salmonella typhimurium RE88 Strain as a New Cancer Vaccine Carrier: Evaluation in a Mouse Model of Cancer
Fan Y, Bai T, Tian Y, Zhou B, Wang Y, Yang L
Drug Design, Development and Therapy 2021, 15:209-222
Published Date: 15 January 2021
Quaternary Lidocaine Derivatives: Past, Present, and Future
Wang Q, Zhang Y, Liu J, Zhang W
Drug Design, Development and Therapy 2021, 15:195-207
Published Date: 14 January 2021
Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions
Wang MN, Yu HT, Li YQ, Zeng Y, Yang S, Yang GP, Pei Q, Huang J
Drug Design, Development and Therapy 2021, 15:185-193
Published Date: 14 January 2021
Combination of Sodium Cantharidinate with Cisplatin Synergistically Hampers Growth of Cervical Cancer
Chen X, Zhou M, Fan W, Yang M, Yang L
Drug Design, Development and Therapy 2021, 15:171-183
Published Date: 13 January 2021
Subcutaneous Delivery of High-Dose/Volume Biologics: Current Status and Prospect for Future Advancements
Badkar AV, Gandhi RB, Davis SP, LaBarre MJ
Drug Design, Development and Therapy 2021, 15:159-170
Published Date: 13 January 2021
Spotlight on Pimavanserin Tartrate and Its Therapeutic Potential in the Treatment of Major Depressive Disorder: The Evidence to Date
Soogrim V, Ruberto VL, Murrough J, Jha MK
Drug Design, Development and Therapy 2021, 15:151-157
Published Date: 13 January 2021
Preparation and Characterization of Tacrolimus-Loaded SLNs in situ Gel for Ocular Drug Delivery for the Treatment of Immune Conjunctivitis
Sun K, Hu K
Drug Design, Development and Therapy 2021, 15:141-150
Published Date: 12 January 2021
Capsaicin Inhibits Proliferation and Induces Apoptosis in Breast Cancer by Down-Regulating FBI-1-Mediated NF-κB Pathway
Chen M, Xiao C, Jiang W, Yang W, Qin Q, Tan Q, Lian B, Liang Z, Wei C
Drug Design, Development and Therapy 2021, 15:125-140
Published Date: 12 January 2021
Chronic Obstructive Pulmonary Disease Treatment and Pharmacist-Led Medication Management
Li LC, Han YY, Zhang ZH, Zhou WC, Fang HM, Qu J, Kan LD
Drug Design, Development and Therapy 2021, 15:111-124
Published Date: 12 January 2021
Network Pharmacology and Experimental Evidence Identify the Mechanism of Astragaloside IV in Oxaliplatin Neurotoxicity
Xu J, Guan Z, Wang X, Sun D, Li Y, Pei B, Lu Y, Yuan L, Zhang X
Drug Design, Development and Therapy 2021, 15:99-110
Published Date: 12 January 2021
Roflumilast Attenuates Doxorubicin-Induced Cardiotoxicity by Targeting Inflammation and Cellular Senescence in Cardiomyocytes Mediated by SIRT1
Zhang S, Wu P, Liu J, Du Y, Yang Z
Drug Design, Development and Therapy 2021, 15:87-97
Published Date: 11 January 2021
A Review of Drug Therapy in Vestibular Schwannoma
Long J, Zhang Y, Huang X, Ren J, Zhong P, Wang B
Drug Design, Development and Therapy 2021, 15:75-85
Published Date: 8 January 2021
Pristimerin Protects Against OVX-Mediated Bone Loss by Attenuating Osteoclast Formation and Activity via Inhibition of RANKL-Mediated Activation of NF-κB and ERK Signaling Pathways
Li X, Lin X, Wu Z, Su Y, Liang J, Chen R, Yang X, Hou L, Zhao J, Liu Q, Xu F
Drug Design, Development and Therapy 2021, 15:61-74
Published Date: 7 January 2021
Inhibition of Pre-B Cell Colony Enhancing Factor Reduces Lung Injury in Rats Receiving Cardiopulmonary Bypass
Lu C, Yang W, Zhou J, Zhang Z, Gong Y, Hu F, Yu W, Dong X
Drug Design, Development and Therapy 2021, 15:51-60
Published Date: 7 January 2021
Lactobacillus plantarum KSFY06 Prevents Inflammatory Response and Oxidative Stress in Acute Liver Injury Induced by D-Gal/LPS in Mice
Li C, Si J, Tan F, Park KY, Zhao X
Drug Design, Development and Therapy 2021, 15:37-50
Published Date: 6 January 2021
RASSF1A Enhances Chemosensitivity of NSCLC Cells Through Activating Autophagy by Regulating MAP1S to Inactivate Keap1-Nrf2 Pathway
Wang J, Zhang X, Yang F, Yang Y, Wang T, Liu W, Zhou H, Zhao W
Drug Design, Development and Therapy 2021, 15:21-35
Published Date: 6 January 2021
Current Status and Perspectives of Protease Inhibitors and Their Combination with Nanosized Drug Delivery Systems for Targeted Cancer Therapy
Rudzińska M, Daglioglu C, Savvateeva LV, Kaci FN, Antoine R, Zamyatnin Jr AA
Drug Design, Development and Therapy 2021, 15:9-20
Published Date: 6 January 2021
Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?
Yu Q, Sun Y
Drug Design, Development and Therapy 2021, 15:1-8
Published Date: 6 January 2021