Menu
Back to Journals » Drug Design, Development and Therapy » Volume 7 » default
Drug Design, Development and Therapy
ISSN: 1177-8881
- View all (3975)
- Volume 17, 2023 (219)
- Volume 16, 2022 (316)
- Volume 15, 2021 (399)
- Volume 14, 2020 (477)
- Volume 13, 2019 (387)
- Volume 12, 2018 (382)
- Volume 11, 2017 (330)
- Volume 10, 2016 (374)
- Volume 9, 2015 (543)
- Volume 8, 2014 (231)
- Volume 7, 2013 (143)
- Volume 6, 2012 (42)
- Volume 5, 2011 (40)
- Volume 4, 2010 (35)
- Volume 3, 2009 (27)
- Volume 2, 2008 (29)
- Volume 1, 2007 (1)
Archive: Volume 7, 2013
Effect of Tianqi antitremor granules on behavioral manifestations and expression of G protein-coupled receptor kinase 6 and β-arrestin1 in levodopa-induced dyskinesia in a rat model of Parkinson's disease
Wu N, Yang X, Song L, Wei J, Liu Z
Drug Design, Development and Therapy 2013, 7:1481-1489
Published Date: 10 December 2013
Disease-modifying drugs in Alzheimer's disease
Ghezzi L, Scarpini E, Galimberti D
Drug Design, Development and Therapy 2013, 7:1471-1479
Published Date: 6 December 2013
Development and characterization of gastroretentive sustained-release formulation by combination of swelling and mucoadhesive approach: a mechanistic study
Sankar R, Jain SK
Drug Design, Development and Therapy 2013, 7:1455-1469
Published Date: 5 December 2013
P-glycoprotein alters blood–brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy
Ma A, Wang C, Chen Y, Yuan W
Drug Design, Development and Therapy 2013, 7:1447-1454
Published Date: 3 December 2013
Atomoxetine affects transcription/translation of the NMDA receptor and the norepinephrine transporter in the rat brain – an in vivo study
Udvardi PT, Föhr KJ, Henes C, Liebau S, Dreyhaupt J, Boeckers TM, Ludolph AG
Drug Design, Development and Therapy 2013, 7:1433-1446
Published Date: 4 December 2013
Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome
Hajishafiha M, Dehghan M, Kiarang N, Sadegh-Asadi N, Shayegh SN, Ghasemi-Rad M
Drug Design, Development and Therapy 2013, 7:1427-1431
Published Date: 3 December 2013
Conversion to generic cyclosporine A in stable chronic patients after heart transplantation
Kraeuter M, Helmschrott M, Erbel C, Gleissner CA, Frankenstein L, Schmack B, Ruhparwar A, Ehlermann P, Katus HA, Doesch AO
Drug Design, Development and Therapy 2013, 7:1421-1426
Published Date: 28 November 2013
Estrogen receptor modulatory effects of germinated brown rice bioactives in the uterus of rats through the regulation of estrogen-induced genes
Muhammad SI, Maznah I, Mahmud RB, Saeed MI, Imam MU, Ishaka A
Drug Design, Development and Therapy 2013, 7:1409-1420
Published Date: 2 December 2013
Canagliflozin: a novel treatment option for type 2 diabetes
Dietrich E, Powell J, Taylor JR
Drug Design, Development and Therapy 2013, 7:1399-1408
Published Date: 22 November 2013
Can the anti-inflammatory activities of β2-agonists be harnessed in the clinical setting?
Theron AJ, Steel HC, Tintinger GR, Feldman C, Anderson R
Drug Design, Development and Therapy 2013, 7:1387-1398
Published Date: 22 November 2013
Drugs in development for treatment of patients with cancer-related anorexia and cachexia syndrome [Retraction]
Mantovani G, Madeddu C, Macciò A
Drug Design, Development and Therapy 2013, 7:1385-1386
Published Date: 21 November 2013
In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models
Schleiferböck S, Scheurer C, Ihara M, Itoh I, Bathurst I, Burrows JN, Fantauzzi P, Lotharius J, Charman SA, Morizzi J, Shackleford DM, White KL, Brun R, Wittlin S
Drug Design, Development and Therapy 2013, 7:1377-1384
Published Date: 15 November 2013
Antituberculosis nanodelivery system with controlled-release properties based on para-amino salicylate–zinc aluminum-layered double-hydroxide nanocomposites
Saifullah B, Hussein MZ, Hussein-Al-Ali SH, Arulselvan P, Fakurazi S
Drug Design, Development and Therapy 2013, 7:1365-1375
Published Date: 13 November 2013
Profile of gantenerumab and its potential in the treatment of Alzheimer's disease
Novakovic D, Feligioni M, Scaccianoce S, Caruso A, Piccinin S, Schepisi C, Errico F, Mercuri NB, Nicoletti F, Nisticò R
Drug Design, Development and Therapy 2013, 7:1359-1364
Published Date: 13 November 2013
Animal models of ulcerative colitis and their application in drug research
Low D, Nguyen DD, Mizoguchi E
Drug Design, Development and Therapy 2013, 7:1341-1357
Published Date: 12 November 2013
New and emerging treatments for symptomatic tardive dyskinesia
Rana AQ, Chaudry ZM, Blanchet PJ
Drug Design, Development and Therapy 2013, 7:1329-1340
Published Date: 6 November 2013
Heart rate reduction for 36 months with ivabradine reduces left ventricular mass in cardiac allograft recipients: a long-term follow-up study
Doesch AO, Mueller S, Erbel C, Gleissner CA, Frankenstein L, Hardt S, Ruhparwar A, Ehlermann P, Dengler T, Katus HA
Drug Design, Development and Therapy 2013, 7:1323-1328
Published Date: 5 November 2013
Molecularly targeted drugs for metastatic colorectal cancer
Cheng YD, Yang H, Chen GQ, Zhang ZC
Drug Design, Development and Therapy 2013, 7:1315-1322
Published Date: 1 November 2013
Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence
Marchal JA, Carrasco E, Ramírez A, Jiménez G, Olmedo C, Peran M, Agil A, Conejo-García A, Cruz-López O, Campos JM, García MA
Drug Design, Development and Therapy 2013, 7:1301-1313
Published Date: 29 October 2013
Glycyrrhetinic acid-modified chitosan nanoparticles enhanced the effect of 5-fluorouracil in murine liver cancer model via regulatory T-cells
Cheng M, Xu H, Wang Y, Chen H, He B, Gao X, Li Y, Han J, Zhang Z
Drug Design, Development and Therapy 2013, 7:1287-1299
Published Date: 25 October 2013
Biodegradable in situ gelling delivery systems containing pilocarpine as new antiglaucoma formulations: effect of a mercaptoacetic acid/N-isopropylacrylamide molar ratio
Lai JY
Drug Design, Development and Therapy 2013, 7:1273-1285
Published Date: 24 October 2013
Advances in the proteomic discovery of novel therapeutic targets in cancer
Guo S, Zou J, Wang G
Drug Design, Development and Therapy 2013, 7:1259-1271
Published Date: 24 October 2013
Increased adherence eight months after switch from twice daily calcineurin inhibitor based treatment to once daily modified released tacrolimus in heart transplantation
Doesch AO, Mueller S, Akyol C, Erbel C, Frankenstein L, Ruhparwar A, Ehlermann P, Dengler TJ, Katus HA
Drug Design, Development and Therapy 2013, 7:1253-1258
Published Date: 21 October 2013
Antioxidant effect of Arabic gum against mercuric chloride-induced nephrotoxicity
Gado AM, Aldahmash BA
Drug Design, Development and Therapy 2013, 7:1245-1252
Published Date: 21 October 2013
Intestinal absorption and biliary elimination of glycyrrhizic acid diethyl ester in rats
Koga K, Kawamura M, Iwase H, Yoshikawa N
Drug Design, Development and Therapy 2013, 7:1235-1243
Published Date: 21 October 2013
Daclatasvir: potential role in hepatitis C
Lee C
Drug Design, Development and Therapy 2013, 7:1223-1233
Published Date: 16 October 2013
Current and future G protein-coupled receptor signaling targets for heart failure therapy
Siryk-Bathgate A, Dabul S, Lymperopoulos A
Drug Design, Development and Therapy 2013, 7:1209-1222
Published Date: 11 October 2013
New developments in the combination treatment of COPD: focus on umeclidinium/vilanterol
Cazzola M, Segreti A, Matera MG
Drug Design, Development and Therapy 2013, 7:1201-1208
Published Date: 10 October 2013
A comparative study of internal laser-assisted and conventional liposuction: a look at the influence of drugs and major surgery on laboratory postoperative values
Przylipiak AF, Galicka E, Donejko M, Niczyporuk M, Przylipiak J
Drug Design, Development and Therapy 2013, 7:1195-1200
Published Date: 11 October 2013
Review of daclizumab and its therapeutic potential in the treatment of relapsing–remitting multiple sclerosis
Reardon J, Perumal JS
Drug Design, Development and Therapy 2013, 7:1187-1193
Published Date: 9 October 2013
Phase II study of whole brain radiotherapy with or without erlotinib in patients with multiple brain metastases from lung adenocarcinoma
Zhuang H, Yuan Z, Wang J, Zhao L, Pang Q, Wang P
Drug Design, Development and Therapy 2013, 7:1179-1186
Published Date: 8 October 2013
8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications
Prachayasittikul V, Prachayasittikul S, Ruchirawat S, Prachayasittikul V
Drug Design, Development and Therapy 2013, 7:1157-1178
Published Date: 4 October 2013
The effect of prostaglandin analogs on the biomechanical properties and central thickness of the cornea of patients with open-angle glaucoma: a 3-year study on 108 eyes
Tsikripis P, Papaconstantinou D, Koutsandrea C, Apostolopoulos M, Georgalas I
Drug Design, Development and Therapy 2013, 7:1149-1156
Published Date: 4 October 2013
The biology of PCSK9 from the endoplasmic reticulum to lysosomes: new and emerging therapeutics to control low-density lipoprotein cholesterol
Poirier S, Mayer G
Drug Design, Development and Therapy 2013, 7:1135-1148
Published Date: 4 October 2013
Clinical experimentation with aerosol antibiotics: current and future methods of administration
Zarogoulidis P, Kioumis I, Porpodis K, Spyratos D, Tsakiridis K, Huang H, Li Q, Turner JF, Browning R, Hohenforst-Schmidt W, Zarogoulidis K
Drug Design, Development and Therapy 2013, 7:1115-1134
Published Date: 2 October 2013
Advances with microRNAs in Parkinson’s disease research
Ma L, Wei L, Wu F, Hu Z, Liu Z, Yuan W
Drug Design, Development and Therapy 2013, 7:1103-1113
Published Date: 1 October 2013
Anti-insulin-like growth factor-IIP3 DNAzymes inhibit cell proliferation and induce caspase-dependent apoptosis in human hepatocarcinoma cell lines
Zhang M, Drummen GPC, Luo S
Drug Design, Development and Therapy 2013, 7:1089-1102
Published Date: 4 October 2013
A novel dimeric thymosin beta 4 with enhanced activities accelerates the rate of wound healing
Xu TJ, Wang Q, Ma XW, Zhang Z, Zhang W, Xue XC, Zhang C, Hao Q, Li WN, Zhang YQ, Li M
Drug Design, Development and Therapy 2013, 7:1075-1088
Published Date: 1 October 2013
Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment
Maioli M, Contini G, Santaniello S, Bandiera P, Pigliaru G, Sanna R, Rinaldi S, Delitala AP, Montella A, Bagella L, Ventura C
Drug Design, Development and Therapy 2013, 7:1063-1073
Published Date: 27 September 2013
Efficacy, tolerability, and acceptability of bupropion for major depressive disorder: a meta-analysis of randomized–controlled trials comparison with venlafaxine
Maneeton N, Maneeton B, Eurviriyanukul K, Srisurapanont M
Drug Design, Development and Therapy 2013, 7:1053-1062
Published Date: 27 September 2013
New structure–activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity
Rangel LP, Winter E, Gauthier C, Terreux R, Chiaradia-Delatorre LD, Mascarello A, Nunes RJ, Yunes RA, Creczynski-Pasa TB, Macalou S, Lorendeau D, Baubichon-Cortay H, Ferreira-Pereira A, Di Pietro A
Drug Design, Development and Therapy 2013, 7:1043-1052
Published Date: 30 September 2013
Corticosteroid transdermal delivery to target swelling, edema and inflammation following facial rejuvenation procedures
Iannitti T, Rottigni V, Palmieri B
Drug Design, Development and Therapy 2013, 7:1035-1041
Published Date: 26 September 2013
Pharmaceutical suspension containing both immediate/sustained-release amoxicillin-loaded gelatin nanoparticles: preparation and in vitro characterization
Harsha S
Drug Design, Development and Therapy 2013, 7:1027-1033
Published Date: 26 September 2013
Preparation and characterization of 6-mercaptopurine-coated magnetite nanoparticles as a drug delivery system
Dorniani D, Hussein MZ, Kura AU, Fakurazi S, Shaari AH, Ahmad Z
Drug Design, Development and Therapy 2013, 7:1015-1026
Published Date: 25 September 2013
Vitamin D in asthma and future perspectives
Huang H, Porpodis K, Zarogoulidis P, Domvri K, Giouleka P, Papaiwannou A, Primikyri S, Mylonaki E, Spyratos D, Hohenforst-Schmidt W, Kioumis I, Zarogoulidis K
Drug Design, Development and Therapy 2013, 7:1003-1013
Published Date: 23 September 2013
Dipeptidyl peptidase-4 inhibitors in type 2 diabetes therapy – focus on alogliptin
Capuano A, Sportiello L, Maiorino MI, Rossi F, Giugliano D, Esposito K
Drug Design, Development and Therapy 2013, 7:989-1001
Published Date: 17 September 2013
Unexpected effects of peripherally administered kynurenic acid on cortical spreading depression and related blood–brain barrier permeability
Oláh G, Herédi J, Menyhárt Á, Czinege Z, Nagy D, Fuzik J, Kocsis K, Knapp L, Krucsó E, Gellért L, Kis Z, Farkas T, Fülöp F, Párdutz Á, Tajti J, Vécsei L, Toldi J
Drug Design, Development and Therapy 2013, 7:981-987
Published Date: 16 September 2013
Prevention of venous thromboembolism in hospitalized acutely ill medical patients: focus on the clinical utility of (low-dose) fondaparinux
Di Nisio M, Porreca E
Drug Design, Development and Therapy 2013, 7:973-980
Published Date: 16 September 2013
S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis [Corrigendum]
Mazo DF, de Oliveira MG, Pereira IV, Cogliati B, Stefano JT, de Souza GF, Rabelo F, Lima FR, Ferreira Alves VA, Carrilho FJ, de Oliveira CP
Drug Design, Development and Therapy 2013, 7:971-972
Published Date: 13 September 2013
Long-acting preparations of exenatide
Cai Y, Wei L, Ma L, Huang X, Tao A, Liu Z, Yuan W
Drug Design, Development and Therapy 2013, 7:963-970
Published Date: 5 September 2013
Hologram quantitative structure–activity relationship and comparative molecular field analysis studies within a series of tricyclic phthalimide HIV-1 integrase inhibitors
Magalhães UO, Souza AMT, Albuquerque MG, Brito MA, Bello ML, Cabral LM, Rodrigues CR
Drug Design, Development and Therapy 2013, 7:953-961
Published Date: 5 September 2013
Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine
Hong X, Wei L, Wu F, Wu Z, Chen L, Liu Z, Yuan W
Drug Design, Development and Therapy 2013, 7:945-952
Published Date: 4 September 2013
Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study
Abdel-Razeq H, Abbasi S, Saadi I, Jaber R , Abdulelah H
Drug Design, Development and Therapy 2013, 7:939-944
Published Date: 30 August 2013
Development, clinical utility, and place of ivacaftor in the treatment of cystic fibrosis
O’Reilly R, Elphick HE
Drug Design, Development and Therapy 2013, 7:929-937
Published Date: 30 August 2013
Identification of PPARγ ligands with One-dimensional Drug Profile Matching
Kovács D, Simon Z, Hári P, Málnási-Csizmadia A, Hegedűs C, Drimba L, Németh J, Sári R, Szilvássy Z, Peitl B
Drug Design, Development and Therapy 2013, 7:917-928
Published Date: 2 September 2013
Surfactant treatment before first breath for respiratory distress syndrome in preterm lambs: comparison of a peptide-containing synthetic lung surfactant with porcine-derived surfactant
van Zyl JM, Smith J
Drug Design, Development and Therapy 2013, 7:905-916
Published Date: 29 August 2013
A review of sitagliptin with special emphasis on its use in moderate to severe renal impairment
Eligar VS, Bain SC
Drug Design, Development and Therapy 2013, 7:893-903
Published Date: 30 August 2013
Novel N-phenylcarbamothioylbenzamides with anti-inflammatory activity and prostaglandin E2 inhibitory properties
Limban C, Missir AV, Fahelelbom KMS, Al-Tabakha MM, Caproiu MT, Sadek B
Drug Design, Development and Therapy 2013, 7:883-892
Published Date: 28 August 2013
Enzalutamide as a second generation antiandrogen for treatment of advanced prostate cancer
Semenas J, Dizeyi N, Persson JL
Drug Design, Development and Therapy 2013, 7:875-881
Published Date: 27 August 2013
Preparation and in vivo absorption evaluation of spray dried powders containing salmon calcitonin loaded chitosan nanoparticles for pulmonary delivery
Sinsuebpol C, Chatchawalsaisin J, Kulvanich P
Drug Design, Development and Therapy 2013, 7:861-873
Published Date: 28 August 2013
Causes, consequences, and treatment of osteoporosis in men
Banu J
Drug Design, Development and Therapy 2013, 7:849-860
Published Date: 22 August 2013
Bioequivalence study of two formulations of candesartan cilexetil tablet in healthy subjects under fasting conditions
Tjandrawinata RR, Setiawati E, Yunaidi DA, Simanjuntak R, Santoso ID, Susanto LW
Drug Design, Development and Therapy 2013, 7:841-847
Published Date: 20 August 2013
In silico identification of EGFR-T790M inhibitors with novel scaffolds: start with extraction of common features
Xiang M, Lei K, Fan W, Lin Y, He G, Yang M, Chen L, Mo Y
Drug Design, Development and Therapy 2013, 7:789-839
Published Date: 14 August 2013
Update on rescue therapies in patients with lamivudine-resistant chronic hepatitis B
Chao DC, Hu KQ
Drug Design, Development and Therapy 2013, 7:777-788
Published Date: 20 August 2013
Clinical study of etomidate emulsion combined with remifentanil in general anesthesia
Weng D, Huang M, Jiang R, Zhan R, Yang C
Drug Design, Development and Therapy 2013, 7:771-776
Published Date: 20 August 2013
Valproic acid-associated low fibrinogen and delayed intracranial hemorrhage: case report and mini literature review
Chen HF, Xu LP, Luo ZY, Yu ZQ, Li ZY, Cui QY, Qin LM, Ren YY, Shen HS, Tang JQ, Jin LJ, Zhu JJ, Wang J, Wang KY, Wu TQ, Wang ZY
Drug Design, Development and Therapy 2013, 7:767-770
Published Date: 13 August 2013
Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseases
Allarakhia M
Drug Design, Development and Therapy 2013, 7:753-766
Published Date: 8 August 2013
N-Palmitoylethanolamine depot injection increased its tissue levels and those of other acylethanolamide lipids
Grillo SL, Keereetaweep J, Grillo MA, Chapman KD, Koulen P
Drug Design, Development and Therapy 2013, 7:747-752
Published Date: 12 August 2013
Developing therapeutic approaches for metachromatic leukodystrophy
Patil SA, Maegawa GHB
Drug Design, Development and Therapy 2013, 7:729-745
Published Date: 8 August 2013
Renal thrombotic microangiopathy caused by interferon beta-1a treatment for multiple sclerosis
Mahe J, Meurette A, Moreau A, Vercel C, Jolliet P
Drug Design, Development and Therapy 2013, 7:723-728
Published Date: 7 August 2013
Aflibercept in wet AMD: specific role and optimal use
Semeraro F, Morescalchi F, Duse S, Parmeggiani F, Gambicorti E, Costagliola C
Drug Design, Development and Therapy 2013, 7:711-722
Published Date: 5 August 2013
Quantification of imatinib in human serum: validation of a high-performance liquid chromatography-mass spectrometry method for therapeutic drug monitoring and pharmacokinetic assays
Rezende VM, Rivellis A, Novaes MM, Chamone DA, Bendit I
Drug Design, Development and Therapy 2013, 7:699-710
Published Date: 5 August 2013
Synthesis and evaluation of mutual azo prodrug of 5-aminosalicylic acid linked to 2-phenylbenzoxazole-2-yl-5-acetic acid in ulcerative colitis
Jilani JA, Shomaf M, Alzoubi KH
Drug Design, Development and Therapy 2013, 7:691-698
Published Date: 31 July 2013
Amrubicin: potential in combination with cisplatin or carboplatin to treat small-cell lung cancer
Ding Q, Zhan J
Drug Design, Development and Therapy 2013, 7:681-689
Published Date: 1 August 2013
Mycobacterium marinum: a potential immunotherapy for Mycobacterium tuberculosis infection
Tian WW, Wang QQ, Liu WD, Shen JP, Wang HS
Drug Design, Development and Therapy 2013, 7:669-680
Published Date: 29 July 2013
Quetiapine versus haloperidol in the treatment of delirium: a double-blind, randomized, controlled trial
Maneeton B, Maneeton N, Srisurapanont M, Chittawatanarat K
Drug Design, Development and Therapy 2013, 7:657-667
Published Date: 24 July 2013
Drugs in development for treatment of patients with cancer-related anorexia and cachexia syndrome
Mantovani G, Madeddu C, Maccio A
Drug Design, Development and Therapy 2013, 7:645-656
Published Date: 12 August 2013
Glyphosate and AMPA inhibit cancer cell growth through inhibiting intracellular glycine synthesis
Li Q, Lambrechts MJ, Zhang Q, Liu S, Ge D, Yin R, Xi M, You Z
Drug Design, Development and Therapy 2013, 7:635-643
Published Date: 24 July 2013
Successful application of extracorporeal membrane oxygenation due to pulmonary hemorrhage secondary to granulomatosis with polyangiitis
Hohenforst-Schmidt W, Petermann A, Visouli A, Zarogoulidis P, Darwiche K, Kougioumtzi I, Tsakiridis K, Machairiotis N, Ketteler M, Zarogoulidis K, Brachmann J
Drug Design, Development and Therapy 2013, 7:627-633
Published Date: 24 July 2013
Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine
Noveck RJ, Douglas PS, Chow SC, Mangum B, Kori S, Kellerman DJ
Drug Design, Development and Therapy 2013, 7:619-625
Published Date: 24 July 2013
Immunomodifiers in combination with conventional chemotherapy in small cell lung cancer: a Phase II, randomized study
Zarogoulidis K, Ziogas E, Boutsikou E, Zarogoulidis P, Darwiche K, Kontakiotis T, Tsakiridis K, Porpodis K, Latsios D, Chatzizisi O, Karapantzos I, Li Q, Kyriazis G
Drug Design, Development and Therapy 2013, 7:611-617
Published Date: 23 July 2013
Profile of bazedoxifene/conjugated estrogens for the treatment of estrogen deficiency symptoms and osteoporosis in women at risk of fracture
Rossini M, Lello S, Sblendorio I, Viapiana O, Fracassi E, Adami S, Gatti D
Drug Design, Development and Therapy 2013, 7:601-610
Published Date: 22 July 2013
Organelle targeting: third level of drug targeting
Sakhrani NM, Padh H
Drug Design, Development and Therapy 2013, 7:585-599
Published Date: 17 July 2013
Intratumoral chemotherapy for lung cancer: re-challenge current targeted therapies
Hohenforst-Schmidt W, Zarogoulidis P, Darwiche K, Vogl T, Goldberg EP, Huang H, Simoff M, Li Q, Browning R, Turner FJ, Le Pivert P, Spyratos D, Zarogoulidis K, Celikoglu SI, Celikoglu F, Brachmann J
Drug Design, Development and Therapy 2013, 7:571-583
Published Date: 18 July 2013
Effect of ranibizumab on serous and vascular pigment epithelial detachments associated with exudative age-related macular degeneration
Panos GD, Gatzioufas Z, Petropoulos IK, Dardabounis D, Thumann G, Hafezi F
Drug Design, Development and Therapy 2013, 7:565-569
Published Date: 10 July 2013
S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis
Mazo DF, de Oliveira MG, Pereira IV, Cogliati B, Stefano JT, de Souza GF, Rabelo F, Lima FR, Ferreira Alves VA, Carrilho FJ, de Oliveira CP
Drug Design, Development and Therapy 2013, 7:553-563
Published Date: 28 June 2013
Endogenous n 3 polyunsaturated fatty acids PUFAs mitigate ovariectomy-induced bone loss by attenuating bone marrow adipogenesis in FAT1 transgenic mice
Chen TY, Zhang ZM, Zheng XC, Wang L, Huang MJ, Qin S, Chen J, Lai PL, Yang CL, Liu J, Dai YF, Jin DD, Bai XC
Drug Design, Development and Therapy 2013, 7:545-552
Published Date: 28 June 2013
A comparative study of the effects of vitamin C, sirolimus, and paclitaxel on the growth of endothelial and smooth muscle cells for cardiovascular medical device applications
Kakade S, Mani G
Drug Design, Development and Therapy 2013, 7:529-544
Published Date: 24 June 2013
Profile of tivozanib and its potential for the treatment of advanced renal cell carcinoma
Cowey CL
Drug Design, Development and Therapy 2013, 7:519-527
Published Date: 21 June 2013
The drug efficacy and adverse reactions in a mouse model of oral squamous cell carcinoma treated with oxaliplatin at different time points during a day
Yang K, Zhao N, Zhao D, Chen D, Li Y
Drug Design, Development and Therapy 2013, 7:511-517
Published Date: 20 June 2013
Reducing lung function decline in patients with idiopathic pulmonary fibrosis: potential of nintedanib
Woodcock HV, Molyneaux PL, Maher TM
Drug Design, Development and Therapy 2013, 7:503-510
Published Date: 19 June 2013
Drug-resistant colon cancer cells produce high carcinoembryonic antigen and might not be cancer-initiating cells
Lee HC, Ling QD, Yu WC, Hung CM, Kao TC, Huang YW, Higuchi A
Drug Design, Development and Therapy 2013, 7:491-502
Published Date: 17 June 2013
Resistance to antivascular endothelial growth factor treatment in age-related macular degeneration
Tranos P, Vakalis A, Asteriadis S, Koukoula S, Vachtsevanos A, Perganta G, Georgalas I
Drug Design, Development and Therapy 2013, 7:485-490
Published Date: 17 June 2013
Early achievement and maintenance of stable asthma control using initially higher-dose inhaled corticosteroids as part of combination therapy: an open-label pilot study
Cheng SL, Wang HC, Kuo SH
Drug Design, Development and Therapy 2013, 7:477-484
Published Date: 17 June 2013
Novel phytochemical–antibiotic conjugates as multitarget inhibitors of Pseudomononas aeruginosa GyrB/ParE and DHFR
Jayaraman P, Sakharkar KR, Lim CS, Siddiqi MI, Dhillon SK, Sakharkar MK
Drug Design, Development and Therapy 2013, 7:449-475
Published Date: 17 June 2013
Osteoporosis – a current view of pharmacological prevention and treatment
Das S, Crockett JC
Drug Design, Development and Therapy 2013, 7:435-448
Published Date: 31 May 2013
Fluocinolone acetonide intravitreal implant for the treatment of diabetic macular edema
Messenger WB, Beardsley RM, Flaxel CJ
Drug Design, Development and Therapy 2013, 7:425-434
Published Date: 24 May 2013
Preparation and evaluation of a multimodal minoxidil microemulsion versus minoxidil alone in the treatment of androgenic alopecia of mixed etiology: a pilot study
Sakr FM, Gado AMI, Mohammed HR, Adam ANI
Drug Design, Development and Therapy 2013, 7:413-423
Published Date: 30 May 2013
Development of a robust cell-based high-throughput screening assay to identify targets of HIV-1 viral protein R dimerization
Zych C, Domling A, Ayyavoo V
Drug Design, Development and Therapy 2013, 7:403-412
Published Date: 24 May 2013
Profile of once-daily zonisamide as monotherapy for treatment of partial seizures in adults
Mula M
Drug Design, Development and Therapy 2013, 7:397-402
Published Date: 14 May 2013
Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets ß-catenin
Nath N, Liu X, Jacobs L, Kashfi K
Drug Design, Development and Therapy 2013, 7:389-396
Published Date: 6 May 2013
Microbubble-mediated ultrasound therapy: a review of its potential in cancer treatment
Ibsen S, Schutt CE, Esener S
Drug Design, Development and Therapy 2013, 7:375-388
Published Date: 3 May 2013
Very rapid effect of pitavastatin on microvascular function in comparison to rosuvastatin: reactive hyperemia peripheral arterial tonometric study
Kono Y, Fukuda S, Shimada K, Nakanishi K, Otsuka K, Kubo T, Jissho S, Taguchi H, Yoshikawa J, Yoshiyama M
Drug Design, Development and Therapy 2013, 7:369-374
Published Date: 3 May 2013
Effectiveness and safety of 0.15% ganciclovir in situ ophthalmic gel for herpes simplex keratitis – a multicenter, randomized, investigator-masked, parallel group study in Chinese patients
Lin T, Gong L, Sun XH, Zhao NQ, Chen W, Yuan HP, Shao Y, Gao MH, Tang H
Drug Design, Development and Therapy 2013, 7:361-368
Published Date: 29 April 2013
Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis
Pitari GM
Drug Design, Development and Therapy 2013, 7:351-360
Published Date: 19 April 2013
Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial
Takami T, Saito Y
Drug Design, Development and Therapy 2013, 7:349-350
Published Date: 17 April 2013
Profile of certolizumab and its potential in the treatment of psoriatic arthritis
Chimenti MS, Saraceno R, Chiricozzi A, Giunta A, Chimenti S, Perricone R
Drug Design, Development and Therapy 2013, 7:339-348
Published Date: 15 April 2013
Current and emerging pharmacological treatments for sarcoidosis: a review
Beegle SH, Barba K, Gobunsuy R, Judson MA
Drug Design, Development and Therapy 2013, 7:325-338
Published Date: 12 April 2013
In vitro and in vivo evaluation of a sublingual fentanyl wafer formulation
Lim SCB, Paech MJ, Sunderland B, Liu Y
Drug Design, Development and Therapy 2013, 7:317-324
Published Date: 12 April 2013
Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis
Miyoshi S, Hamada H, Ito R, Katayama H, Irifune K, Suwaki T, Nakanishi N, Kanematsu T, Dote K, Aibiki M, Okura T, Higaki J
Drug Design, Development and Therapy 2013, 7:305-316
Published Date: 10 April 2013
Effects of vildagliptin (Galvus®) therapy in patients with type 2 diabetes mellitus after heart transplantation
Gueler I, Mueller S, Helmschrott M, Oeing CU, Erbel C, Frankenstein L, Gleissner C, Ruhparwar A, Ehlermann P, Dengler TJ, Katus HA, Doesch AO
Drug Design, Development and Therapy 2013, 7:297-303
Published Date: 8 April 2013
Management of difficult-to-treat patients with ulcerative colitis: focus on adalimumab
Armuzzi A, Pugliese D, Nardone OM, Guidi L
Drug Design, Development and Therapy 2013, 7:289-296
Published Date: 8 April 2013
Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics
Liu L, Ma Y, Wang RL, Xu WR, Wang SQ, Chou KC
Drug Design, Development and Therapy 2013, 7:279-288
Published Date: 8 April 2013
Phentermine and topiramate for the management of obesity: a review
Cosentino G, Conrad AO, Uwaifo GI
Drug Design, Development and Therapy 2013, 7:267-278
Published Date: 5 April 2013
Potential role of tedizolid phosphate in the treatment of acute bacterial skin infections
Urbina O, Ferrández O, Espona M, Salas E, Ferrández I, Grau S
Drug Design, Development and Therapy 2013, 7:243-265
Published Date: 3 April 2013
Effect of 7-Difluoromethyl-5, 4΄-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE-/- mice induced by a cholesterol-rich diet
Zhang Y, Li L, You J, Cao J, Fu X
Drug Design, Development and Therapy 2013, 7:233-242
Published Date: 3 April 2013
Generalized in vitro-in vivo relationship (IVIVR) model based on artificial neural networks
Mendyk A, Tuszyński PK, Polak S, Jachowicz R
Drug Design, Development and Therapy 2013, 7:223-232
Published Date: 27 March 2013
Hepatocyte-targeting gene transfer mediated by galactosylated poly(ethylene glycol)- graft-polyethylenimine derivative
Wang YQ, Su J, Cai WW, Lu P, Yuan LF, Jin T, Chen SY, Sheng J
Drug Design, Development and Therapy 2013, 7:211-221
Published Date: 26 March 2013
New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast
Palfreeman AC, McNamee KE, McCann FE
Drug Design, Development and Therapy 2013, 7:201-210
Published Date: 27 March 2013
Development of primary malignant melanoma during treatment with a TNF-α antagonist for severe Crohn’s disease: a case report and review of the hypothetical association between TNF-α blockers and cancer
Kouklakis G, Efremidou EI, Pitiakoudis M, Liratzopoulos N, Polychronidis AC
Drug Design, Development and Therapy 2013, 7:195-199
Published Date: 27 March 2013
Novel 4-substituted phenyl-2,2'-bichalcophenes and aza-analogs as antibacterial agents: a structural activity relationship
Hussin WA, Ismail MA, El-Sayed WM
Drug Design, Development and Therapy 2013, 7:185-193
Published Date: 22 March 2013
Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial
Takami T, Saito Y
Drug Design, Development and Therapy 2013, 7:175-183
Published Date: 22 March 2013
A review of tasquinimod in the treatment of advanced prostate cancer
Williamson SC, Hartley AE, Heer R
Drug Design, Development and Therapy 2013, 7:167-174
Published Date: 21 March 2013
Successful management of an inadvertent excessive treprostinil overdose
Hohenforst-Schmidt W, Hornig J, Friedel N, Zarogoulidis P, Zarogoulidis K, Brachmann J
Drug Design, Development and Therapy 2013, 7:161-165
Published Date: 21 March 2013
Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells
Dai ZJ, Gao J, Kang HF, Ma YG, Ma XB, Lu WF, Lin S, Ma HB, Wang XJ, Wu WY
Drug Design, Development and Therapy 2013, 7:149-159
Published Date: 19 March 2013
The effect of a peptide-containing synthetic lung surfactant on gas exchange and lung mechanics in a rabbit model of surfactant depletion
van Zyl JM, Smith J, Hawtrey A
Drug Design, Development and Therapy 2013, 7:139-148
Published Date: 11 March 2013
Alemtuzumab: evidence for its potential in relapsing–remitting multiple sclerosis
Brown JWL, Coles AJ
Drug Design, Development and Therapy 2013, 7:131-138
Published Date: 6 March 2013
The therapeutic efficacy of propranolol in children with recurrent primary epistaxis
Bjelakovic B, Bojanovic M, Lukic S, Saranac L, Vukomanovic V, Prijic S, Zivkovic N, Randjelovic D
Drug Design, Development and Therapy 2013, 7:127-129
Published Date: 1 March 2013
Advances with RNA interference in Alzheimer’s disease research
Chen S, Ge X, Chen Y, Lv N, Liu Z, Yuan W
Drug Design, Development and Therapy 2013, 7:117-125
Published Date: 22 February 2013
Profile of alisporivir and its potential in the treatment of hepatitis C
Gallay PA, Lin K
Drug Design, Development and Therapy 2013, 7:105-115
Published Date: 15 February 2013
Sitagliptin as add-on therapy in insulin deficiency: biomarkers of therapeutic efficacy respond differently in type 1 and type 2 diabetes
Giampietro O, Giampietro C, Della Bartola L, Masoni MC, Matteucci E
Drug Design, Development and Therapy 2013, 7:99-104
Published Date: 14 February 2013
An early indicator of drug success: Top Journal Selectivity Index
Kissin I
Drug Design, Development and Therapy 2013, 7:93-98
Published Date: 13 February 2013
Formulation and in vitro and in vivo evaluation of film-coated montelukast sodium tablets using Opadry® yellow 20A82938 on an industrial scale
Zaid AN, Natour S, Qaddomi A, Abu Ghoush A
Drug Design, Development and Therapy 2013, 7:83-91
Published Date: 7 February 2013
Antimutagenic and antioxidant activity of novel 4-substituted phenyl-2,2'-bichalcophenes and aza-analogs
El-Sayed WM, Hussin WA
Drug Design, Development and Therapy 2013, 7:73-81
Published Date: 4 February 2013
Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation
Wu X, Hayes D Jr, Zwischenberger JB, Kuhn RJ, Mansour HM
Drug Design, Development and Therapy 2013, 7:59-72
Published Date: 4 February 2013
Risk factors in patients with AFB smear-positive sputum who receive inappropriate antituberculous treatment
Chang CY, Hong JY, Yuan MK, Chang SJ, Lee YM, Chang SC, Hsu LC, Cheng SL
Drug Design, Development and Therapy 2013, 7:53-58
Published Date: 31 January 2013
Emerging treatment options for nasopharyngeal carcinoma
Zhang L, Chen QY, Liu H, Tang LQ, Mai HQ
Drug Design, Development and Therapy 2013, 7:37-52
Published Date: 1 February 2013
Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement
Malagola R, Arrico L, Giannotti R, Pattavina L
Drug Design, Development and Therapy 2013, 7:33-36
Published Date: 23 January 2013
Hippuric acid nanocomposite enhances doxorubicin and oxaliplatin-induced cytotoxicity in MDA-MB231, MCF-7 and Caco2 cell lines
Hussein Al Ali SH, Al-Qubaisi M, Hussein MZ, Ismail M, Bullo S
Drug Design, Development and Therapy 2013, 7:25-31
Published Date: 14 January 2013
Impact of ghrelin on vitreous cytokine levels in an experimental uveitis model
Turgut B, Gul FC, Dagli F, Ilhan N, Ozgen M
Drug Design, Development and Therapy 2013, 7:19-24
Published Date: 9 January 2013
New treatments for myasthenia: a focus on antisense oligonucleotides
Angelini C, Martignago S, Bisciglia M
Drug Design, Development and Therapy 2013, 7:13-17
Published Date: 10 January 2013
Preliminary study of highly cross-linked hyaluronic acid-based combination therapy for management of knee osteoarthritis-related pain
Palmieri B, Rottigni V, Iannitti T
Drug Design, Development and Therapy 2013, 7:7-12
Published Date: 7 January 2013
Single early instillation of mitomycin C and urinary alkalinization in low-risk non-muscle-invasive bladder cancer: a preliminary study
Ersoy H, Yaytokgil M, Karakoyunlu AN, Topaloglu H, Sagnak L, Ozok HU
Drug Design, Development and Therapy 2013, 7:1-6
Published Date: 28 December 2012