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Drug Design, Development and Therapy


Archive: Volume 2, 2008

Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry

Klaus Braun, Manfred Wiessler, Volker Ehemann, Ruediger Pipkorn, Herbert Spring, et al

Drug Design, Development and Therapy 2008, 2:289-301

Published Date: 4 January 2009

Raltegravir in the management of HIV-infected patients

Hans-Jürgen Stellbrink

Drug Design, Development and Therapy 2008, 2:281-288

Published Date: 23 December 2008

Ambrisentan for the treatment of pulmonary arterial hypertension

Brian Casserly, James R Klinger

Drug Design, Development and Therapy 2008, 2:265-280

Published Date: 4 December 2008

Drug design with Cdc7 kinase: a potential novel cancer therapy target

Masaaki Sawa, Hisao Masai

Drug Design, Development and Therapy 2008, 2:255-264

Published Date: 18 November 2008

Once-daily transdermal rivastigmine in the treatment of Alzheimer’s disease

Andreas Wentrup, Wolfgang H Oertel, Richard Dodel

Drug Design, Development and Therapy 2008, 2:245-254

Published Date: 11 November 2008

Development and targeted use of nilotinib in chronic myeloid leukemia

Carmen Fava, Hagop Kantarjian, Jorge Cortes, Elias Jabbour

Drug Design, Development and Therapy 2008, 2:233-243

Published Date: 10 November 2008

Antidiabetic Bis-Maltolato-OxoVanadium(IV): Conversion of inactive trans- to bioactive cis-BMOV for possible binding to target PTP-1B

Thomas Scior, Hans-Georg Mack, José Antonio Guevara García, Wolfhard Koch

Drug Design, Development and Therapy 2008, 2:221-231

Published Date: 18 November 2008

Review of pramlintide as adjunctive therapy in treatment of type 1 and type 2 diabetes

Gina Ryan, Tim A Briscoe, Lynette Jobe

Drug Design, Development and Therapy 2008, 2:203-214

Published Date: 16 October 2008

Next-generation anthracycline for the management of small cell lung cancer: focus on amrubicin

Michiko Yamamoto, Akira Takakura, Noriyuki Masuda

Drug Design, Development and Therapy 2008, 2:189-192

Published Date: 28 September 2008

Polyethylenimine-mediated gene delivery to the lung and therapeutic applications

Sante Di Gioia, Massimo Conese

Drug Design, Development and Therapy 2008, 2:163-188

Published Date: 19 September 2008

Maraviroc in the treatment of HIV infection

Neelanjana Ray

Drug Design, Development and Therapy 2008, 2:151-161

Published Date: 20 August 2008

Surface activity of surfactant spiked with vitamin A

Vadim Bronshtein, Vugranam Venkatesh, Jas Aulakh, Philippe Chessex

Drug Design, Development and Therapy 2008, 2:145-150

Published Date: 14 August 2008

Comparative in vivo bioequivalence and in vitro dissolution of two valproic acid sustained-release formulations

Akira Fujii, Norio Yasui-Furukori, Taku Nakagami, Takenori Niioka, Manabu Saito, et al

Drug Design, Development and Therapy 2008, 2:139-144

Published Date: 11 August 2008

Submucosal injection solution for gastrointestinal tract endoscopic mucosal resection and endoscopic submucosal dissection

Toshio Uraoka, Yutaka Saito, Kazuhide Yamamoto, Takahiro Fujii

Drug Design, Development and Therapy 2008, 2:131-138

Published Date: 11 August 2008

Structure-based design of anticancer prodrug PABA/NO

Xinhua Ji, Ajai Pal, Ravi Kalathur, Xun Hu, Yijun Gu, et al

Drug Design, Development and Therapy 2008, 2:123-130

Published Date: 11 August 2008

Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China

Guangyu Ma, Hideaki Shimada, Kenzo Hiroshima, Yuji Tada, Nobuo Suzuki, Masatoshi Tagawa

Drug Design, Development and Therapy 2008, 2:115-122

Published Date: 11 August 2008

A phase I clinical study of VB4-845: Weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck

Glen C MacDonald, Michèle Rasamoelisolo, Joycelyn Entwistle, Jeannick Cizeau, Denis Bosc, et al

Drug Design, Development and Therapy 2008, 2:105-114

Published Date: 25 June 2008

Changes in CD4+ T-cells and HIV RNA resulting from combination of anti-TB therapy with Dzherelo in TB/HIV dually infected patients

Lyudmila G Nikolaeva, Tatyana V Maystat, Lilia A Masyuk, Volodymyr S Pylypchuk, Yuri L Volyanskii, Galyna A Kutsyna

Drug Design, Development and Therapy 2008, 2:87-93

Published Date: 1 May 2008

Modafinil in the treatment of excessive sleepiness

Jonathan RL Schwartz

Drug Design, Development and Therapy 2008, 2:71-85

Published Date: 20 May 2008

Discovery, development, and clinical application of sugammadex sodium, a selective relaxant binding agent

Mark Welliver, John McDonough, Nicholas Kalynych, Robert Redfern

Drug Design, Development and Therapy 2008, 2:49-59

Published Date: 25 February 2008

Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study

Harald J Hamre, Claudia M Witt, Anja Glockmann, Renatus Ziegler, Gunver S Kienle et al

Drug Design, Development and Therapy 2008, 2:25-37

Published Date: 8 January 2008

A safety-modified SV40 Tag developed for human cancer immunotherapy

Stephanie S Tseng-Rogenski, Mohamed S Arredouani, June F Escara-Wilke, Yilin C Neeley, Michael J Imperiale et al

Drug Design, Development and Therapy 2008, 2:17-24

Published Date: 8 January 2008

Pharmaco-management of inhalation injuries for burn survivors

Anthony C Bartley, Dale W Edgar, Fiona M Wood

Drug Design, Development and Therapy 2008, 2:9-16

Published Date: 8 January 2008

Aerosol delivery by an ultrasonic nebulizer during different mechanical ventilation settings in a lung model – a pilot study

Michael Winterhalter, Michael Bund, Nawid Khaladj, Christian Hagl, Andre Simon, et al

Drug Design, Development and Therapy 2008, 2:1-7

Published Date: 8 January 2008