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Drug Design, Development and Therapy
ISSN: 1177-8881
- View all (3879)
- Volume 17, 2023 (123)
- Volume 16, 2022 (316)
- Volume 15, 2021 (399)
- Volume 14, 2020 (477)
- Volume 13, 2019 (387)
- Volume 12, 2018 (382)
- Volume 11, 2017 (330)
- Volume 10, 2016 (374)
- Volume 9, 2015 (543)
- Volume 8, 2014 (231)
- Volume 7, 2013 (143)
- Volume 6, 2012 (42)
- Volume 5, 2011 (40)
- Volume 4, 2010 (35)
- Volume 3, 2009 (27)
- Volume 2, 2008 (29)
- Volume 1, 2007 (1)
Journal Articles:
- 3,879 records -
Thinkful of Icariin Induces Triple-Negative Breast Cancer Cell Apoptosis and Suppresses Invasion by Inhibiting the JNK/c-Jun Signaling Pathway [Response to Letter]
Gao S, Zhang X, Liu J, Lv Y, Shi W
Drug Design, Development and Therapy 2023, 17:1611-1612
Published Date: 29 May 2023
0.5–5% Supramolecular Salicylic Acid Hydrogel is Safe for Long-Term Topical Application and Improves the Expression of Genes Related to Skin Barrier Homeostasis in Mice Models
Zhou C, Hua C, Liang Q, Al Rudaisat M, Chen S, Song Y, Zhu J, Cheng H
Drug Design, Development and Therapy 2023, 17:1593-1609
Published Date: 26 May 2023
Profile of Luspatercept in the Treatment of Anemia in Adults with Non-Transfusion-Dependent β-Thalassemia (NTDT): Design, Development and Potential Place in Therapy
Musallam KM, Taher AT, Kattamis A, Kuo KH, Sheth S, Cappellini MD
Drug Design, Development and Therapy 2023, 17:1583-1591
Published Date: 25 May 2023
Paeonol Promotes Reendothelialization After Vascular Injury Through Activation of c-Myc/VEGFR2 Signaling Pathway
Wang Y, Wang Z, Wu X, Zhu S, Guo Q, Jin Z, Chen Z, Zhang D, Hu W, Xu H, Shi L, Yang L, Wang Y
Drug Design, Development and Therapy 2023, 17:1567-1582
Published Date: 24 May 2023
Effect of Flexible Half-Dose Gonadotropin-Releasing Hormone Antagonist Protocol on in vitro Fertilization Outcome in Predicted Normal Responder: A Study Protocol for a Multicentered, Randomized, Non-Inferiority, Parallel Controlled Trial
Ma YJ, Li MY, Song JY, Sun ZG
Drug Design, Development and Therapy 2023, 17:1557-1566
Published Date: 24 May 2023
Prophylactic Norepinephrine and Phenylephrine Boluses to Prevent Postspinal Anesthesia Hypotension During Cesarean Section: A Randomized Sequential Allocation Dose-Finding Study
Guo L, Xu X, Qin R, Shi Y, Xue W, He L, Ma S, Chen Y
Drug Design, Development and Therapy 2023, 17:1547-1555
Published Date: 23 May 2023
Network Pharmacology Study of Bioactive Components and Molecular Mechanisms of the Glycoside Fraction from Picrorhiza scrophulariiflora Against Experimental Colitis
Wu P, Chang C, Zhu G, Zhai L, Zhang X, Huan Q, Gao Z, Deng H, Liang Y, Xiao H
Drug Design, Development and Therapy 2023, 17:1531-1546
Published Date: 23 May 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies
Li Y, Zhu S, Luo J, Tong Y, Zheng Y, Ji L, He Z, Jing Q, Huang J, Zhang Y, Bi Q
Drug Design, Development and Therapy 2023, 17:1515-1529
Published Date: 22 May 2023
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease
Tang C, Deng X, Qu J, Miao Y, Tian L, Zhang M, Li X, Sun B, Chen L
Drug Design, Development and Therapy 2023, 17:1503-1514
Published Date: 18 May 2023
Effects of Empagliflozin on Gut Microbiota in Heart Failure with a Preserved Ejection Fraction: The Design of a Pragmatic Randomized, Open-Label Controlled Trial (EMPAGUM)
Guan XQ, Wang CH, Cheng P, Fu LY, Wu QJ, Cheng G, Guan L, Sun ZJ
Drug Design, Development and Therapy 2023, 17:1495-1502
Published Date: 18 May 2023
Genetic Diversity and Characteristics of Drug Resistance Among Treatment-Naive People Living with HIV in Xi’an, China
Xia H, Jin J, Ba H, Zhang Y, Li J, Guo R, Li Y, Ma P, Zhang Y
Drug Design, Development and Therapy 2023, 17:1485-1494
Published Date: 17 May 2023
Dexmedetomidine as an Adjuvant in Peripheral Nerve Block
Chen Z, Liu Z, Feng C, Jin Y, Zhao X
Drug Design, Development and Therapy 2023, 17:1463-1484
Published Date: 17 May 2023
Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
Özdemir Ç, Arslan M, Küçük A, Yığman Z, Dursun AD
Drug Design, Development and Therapy 2023, 17:1453-1462
Published Date: 17 May 2023
Nano-Emulsion Based Gel for Topical Delivery of an Anti-Inflammatory Drug: In vitro and in vivo Evaluation
Gaber DA, Alsubaiyel AM, Alabdulrahim AK, Alharbi HZ, Aldubaikhy RM, Alharbi RS, Albishr WK, Mohamed HA
Drug Design, Development and Therapy 2023, 17:1435-1451
Published Date: 15 May 2023
Thoughtful Discussion on Article “Antimicrobial Peptide Cec4 Eradicates Multidrug-Resistant Acinetobacter baumannii in vitro and in vivo” [Letter]
Hidayat S, Isnawati R, Panjaitan NSD
Drug Design, Development and Therapy 2023, 17:1433-1434
Published Date: 15 May 2023
Cinchonine, a Potential Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist, Lowers Blood Glucose and Ameliorates Non-Alcoholic Steatohepatitis
Xue H, Xing HJ, Wang B, Fu C, Zhang YS, Qiao X, Guo C, Zhang XL, Hu B, Zhao X, Deng LJ, Zhu XC, Zhang Y, Liu YF
Drug Design, Development and Therapy 2023, 17:1417-1432
Published Date: 11 May 2023
Nalbuphine May Be Superior to Sufentanil in Relieving Postcesarean Uterine Contraction Pain in Multiparas: A Retrospective Cohort Study
Zheng K, Chen B, Sun J
Drug Design, Development and Therapy 2023, 17:1405-1415
Published Date: 8 May 2023
Prolonged Anesthesia Induction to Delivery Time Did Not Influence Plasma Remifentanil Concentration in Neonates
Cai M, Liu H, Peng Y, Miao JK, Lei XF, Yu J
Drug Design, Development and Therapy 2023, 17:1395-1403
Published Date: 8 May 2023
Identification of Piperlongumine as Potent Inhibitor of Necroptosis
He X, Li M, Ye Z, You X, Wang J, Xiao X, Zhu G, Wei J, Zha Y
Drug Design, Development and Therapy 2023, 17:1387-1394
Published Date: 8 May 2023
16S rRNA and Metagenomics Combined with UPLC-Q/TOF-MS Metabolomics Analysis Reveals the Potential Mechanism of Radix Astragali Against Hyperuricemia in Mice
Deng S, Cai K, Pei C, Zhang X, Xiao X, Chen Y, Chen Y, Liang R, Chen Y, Li P, Xie Z, Liao Q
Drug Design, Development and Therapy 2023, 17:1371-1386
Published Date: 6 May 2023
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway
Wang Y, Gao G, Wei X, Zhang Y, Yu J
Drug Design, Development and Therapy 2023, 17:1357-1369
Published Date: 5 May 2023
Efficacy and Safety of a Subanesthetic Dose of Esketamine Combined with Propofol in Patients with Obesity Undergoing Painless Gastroscopy: A Prospective, Double-Blind, Randomized Controlled Trial
Zheng L, Wang Y, Ma Q, Liang W, Zhang X, Ren Z, Qin W, Meng F, Li Y, Fan G, Yin N
Drug Design, Development and Therapy 2023, 17:1347-1356
Published Date: 4 May 2023
A Systematic Review of Systematic Reviews on the Use of Aromatase Inhibitors for the Treatment of Endometriosis: The Evidence to Date
Peitsidis P, Tsikouras P, Laganà AS, Laios A, Gkegkes ID, Iavazzo C
Drug Design, Development and Therapy 2023, 17:1329-1346
Published Date: 4 May 2023
The Application of Dupilumab to Pediatric Patients Aged 6–11yrs with Moderate-to-Severe Atopic Dermatitis Whose Disease is Not Adequately Controlled: The Clinical Data so Far
Balboul S, Kahn J, Tracy A, Peacock A, Cline A
Drug Design, Development and Therapy 2023, 17:1323-1327
Published Date: 1 May 2023
Feasibility and Safety of Remazolam versus Propofol When Inserting Laryngeal Masks Without Muscle Relaxants During Hysteroscopy
Tang S, Lu J, Xu C, Wei L, Mei S, Chen R, Meng QT
Drug Design, Development and Therapy 2023, 17:1313-1322
Published Date: 1 May 2023
Clinical Utility of Osilodrostat in Cushing’s Disease: Review of Currently Available Literature
Perosevic M, Tritos NA
Drug Design, Development and Therapy 2023, 17:1303-1312
Published Date: 27 April 2023
Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis
Yuan S, Zuo B, Zhou SC, Wang M, Tan KY, Chen ZW, Cao WF
Drug Design, Development and Therapy 2023, 17:1289-1302
Published Date: 27 April 2023
AS-605240 Blunts Osteoporosis by Inhibition of Bone Resorption
Sun J, Cai G, Shen J, Cheng P, Zhang J, Jiang D, Xu X, Lu F, Chen L, Chen H
Drug Design, Development and Therapy 2023, 17:1275-1288
Published Date: 27 April 2023
Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4
Vaas S, Zimmermann MO, Klett T, Boeckler FM
Drug Design, Development and Therapy 2023, 17:1247-1274
Published Date: 25 April 2023
Thinkful of Icariin Induces Triple-Negative Breast Cancer Cell Apoptosis and Suppresses Invasion by Inhibiting the JNK/c-Jun Signaling Pathway [Letter]
Mariya SS, Rinendyaputri R, Nikmah UA
Drug Design, Development and Therapy 2023, 17:1245-1246
Published Date: 24 April 2023
Cardiopulmonary Adverse Events of Remimazolam versus Propofol During Cervical Conization: A Randomized Controlled Trial
Wang L, Wang Y, Ma L, Wang Y, Mu X, Huang Z, Zheng Z, Nie H
Drug Design, Development and Therapy 2023, 17:1233-1243
Published Date: 22 April 2023
Development of Verapamil Hydrochloride-loaded Biopolymer-based Composite Electrospun Nanofibrous Mats: In vivo Evaluation of Enhanced Burn Wound Healing without Scar Formation
Barakat HS, Freag MS, Gaber SM, Al Oufy A, Abdallah OY
Drug Design, Development and Therapy 2023, 17:1211-1231
Published Date: 21 April 2023
A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects
Kim HC, Lee S, Sung S, Kim E, Jang IJ, Chung JY
Drug Design, Development and Therapy 2023, 17:1203-1210
Published Date: 21 April 2023
Virtual Screening and Biological Evaluation of Novel Low Molecular Weight Protein Tyrosine Phosphatase Inhibitor for the Treatment of Insulin Resistance
Feng B, Dong X, Liu Z, Zhang J, Liu H, Xu Y
Drug Design, Development and Therapy 2023, 17:1191-1201
Published Date: 21 April 2023
Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice
Gai C, Xing X, Song Y, Zhao Y, Jiang Z, Cheng Y, Xiao Y, Wang Z
Drug Design, Development and Therapy 2023, 17:1175-1189
Published Date: 21 April 2023
Knowledge Mapping of Drug Repositioning’s Theme and Development
Lang X, Liu J, Zhang G, Feng X, Dan W
Drug Design, Development and Therapy 2023, 17:1157-1174
Published Date: 18 April 2023
Effects of the Different Doses of Esketamine on Postoperative Quality of Recovery in Patients Undergoing Modified Radical Mastectomy: A Randomized, Double-Blind, Controlled Trial [Response to Letter]
Zhu M, Xu S, Ju X, Wang S, Yu X
Drug Design, Development and Therapy 2023, 17:1155-1156
Published Date: 18 April 2023
Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling [Retraction]
Alotaibi MF, Al-Joufi F, Abou Seif HS, Alzoghaibi MA, Djouhri L, Ahmeda AF, Mahmoud AM
Drug Design, Development and Therapy 2023, 17:1153-1154
Published Date: 13 April 2023
Berberine Alleviates Acute Lung Injury in Septic Mice by Modulating Treg/Th17 Homeostasis and Downregulating NF-κB Signaling
Chen L, Liu X, Wang X, Lu Z, Ye Y
Drug Design, Development and Therapy 2023, 17:1139-1151
Published Date: 13 April 2023
Resveratrol Improves Paclitaxel-Induced Cognitive Impairment in Mice by Activating SIRT1/PGC-1α Pathway to Regulate Neuronal State and Microglia Cell Polarization
Liu X, Tang M, He TY, Zhao S, Li HZ, Li Z, Guo YX, Wang XL
Drug Design, Development and Therapy 2023, 17:1125-1138
Published Date: 12 April 2023
Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects
Kim HC, Yang E, Ban MS, Kim YK, Hong SH, Jung J, Jang IJ, Lee S
Drug Design, Development and Therapy 2023, 17:1115-1124
Published Date: 12 April 2023
Pharmacokinetic Interactions Between Bazedoxifene and Cholecalciferol: An Open-Label, Randomized, Crossover Study in Healthy Male Volunteers
Lee MH, Yoon SK, Kim H, Cho YS, Han S, Lee SH, Bae KS, Jung J, Hong SH, Lim HS
Drug Design, Development and Therapy 2023, 17:1107-1114
Published Date: 12 April 2023
Review of Mavacamten for Obstructive Hypertrophic Cardiomyopathy and Future Directions
Dong T, Alencherry B, Ospina S, Desai MY
Drug Design, Development and Therapy 2023, 17:1097-1106
Published Date: 8 April 2023
Celastrol: A Potential Natural Lead Molecule for New Drug Design, Development and Therapy for Memory Impairment
Amir Yusri MA, Sekar M, Wong LS, Gan SH, Ravi S, Subramaniyan V, Mat Rani NNI, Chidambaram K, Begum MY, Ramar M, Safi SZ, Selvaraj S, Wu YS, Revathy P, Fuloria S, Fuloria NK, Lum PT, Djearamane S
Drug Design, Development and Therapy 2023, 17:1079-1096
Published Date: 8 April 2023
Chemistry, Biosynthesis and Pharmacology of Streptonigrin: An Old Molecule with Future Prospects for New Drug Design, Development and Therapy
Nabihah Nasir N, Sekar M, Ravi S, Wong LS, Sisinthy SP, Gan SH, Subramaniyan V, Chidambaram K, Mat Rani NNI, Begum MY, Ramar M, Safi SZ, Selvaraj S, Chinna Maruthu SK, Fuloria S, Fuloria NK, Lum PT, Djearamane S
Drug Design, Development and Therapy 2023, 17:1065-1078
Published Date: 8 April 2023
TMF Inhibits miR-29a/Wnt/β-Catenin Signaling Through Upregulating Foxo3a Activity in Osteoarthritis Chondrocytes [Retraction]
Huang X, Chen Z, Shi W, Zhang R, Li L, Liu H, Wu L
Drug Design, Development and Therapy 2023, 17:1063-1064
Published Date: 7 April 2023
Effectiveness and Safety of a Fixed-Dose Combination of Valsartan and Rosuvastatin (Rovatitan® Tablet) in Patients with Concomitant Hypertension and Hyperlipidemia: An Observational Study
Lee KJ, Ryu JK, Cho YH, Shin WY, Kim JS, Yoon YW, Jang JY, Kim WH, Beom JW, Kang SM
Drug Design, Development and Therapy 2023, 17:1047-1062
Published Date: 6 April 2023
Antitumor Effects of Hydromorphone on Human Gastric Cancer Cells in vitro
Liang B, Li C, Zhou Z, Xie Y
Drug Design, Development and Therapy 2023, 17:1037-1045
Published Date: 6 April 2023
Effects of Combined Use of Salbutamol/Budesonide in Thoracic Surgery on Postoperative Myocardial Injury (MINS) – A Prospective Randomized Clinical Trial
Lin S, Zhang Y, Huang X, Zhang X, Cheng E, Zhou Z, Liu J
Drug Design, Development and Therapy 2023, 17:1025-1036
Published Date: 1 April 2023
Therapeutic Mechanism of Baicalin in Experimental Colitis Analyzed Using Network Pharmacology and Metabolomics
Wu Q, Wu X, Wang M, Liu K, Li Y, Ruan X, Qian L, Meng L, Sun Z, Zhu L, Wu J, Mu G
Drug Design, Development and Therapy 2023, 17:1007-1024
Published Date: 31 March 2023