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Drug Design, Development and Therapy

ISSN: 1177-8881


Journal Articles:

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Pharmacokinetics and Bioequivalence of Apremilast Tablets in Chinese Healthy Subjects Under Fasting and Postprandial States

Bai W, Sun X, Qiu B, Guo C, Song H, Hu Y, Zhang X, Yin P, Wang X, Dong Z

Drug Design, Development and Therapy 2024, 18:2273-2285

Published Date: 14 June 2024

The Benefit of the Optimized Formula of Yinxieling in Psoriasis Vulgaris via Regulation on Autophagy Based on microRNA Expression Profile and Network Pharmacology Analysis

Lu Y, Pan S, Li W, Qi Y, Li L, Yan YH, Wei J, Yao DN, Wu J, Deng H, Ye S, Chen H, Chen Q, Gao H, Han L, Lu C

Drug Design, Development and Therapy 2024, 18:2257-2272

Published Date: 14 June 2024

Effects of the Application Local Zoledronic Acid On Different Dental Implants in Rats On Osseointegration

Bingul MB, Gul M, Dundar S, Bozoglan A, Kirtay M, Ozupek MF, Ozcan EC, Habek O, Tasdemir I

Drug Design, Development and Therapy 2024, 18:2249-2256

Published Date: 14 June 2024

Microbiome Metabolomic Analysis of the Anxiolytic Effect of Baihe Dihuang Decoction in a Rat Model of Chronic Restraint Stress

Tang L, Liu J, Yang H, Zhao HQ, Hu C, Ma SJ, Qing YH, Yang L, Zhou RR, Zhang SH

Drug Design, Development and Therapy 2024, 18:2227-2248

Published Date: 12 June 2024

Effectiveness of Spironolactone in Reducing Osteoporosis and Future Fracture Risk in Middle-Aged and Elderly Hypertensive Patients

Song S, Cai X, Hu J, Zhu Q, Shen D, Ma H, Zhang Y, Ma R, Yang W, Hong J, Zhang D, Li N

Drug Design, Development and Therapy 2024, 18:2215-2225

Published Date: 12 June 2024

MTCH2 in Metabolic Diseases, Neurodegenerative Diseases, Cancers, Embryonic Development and Reproduction

Peng X, Yang Y, Hou R, Zhang L, Shen C, Yang X, Luo Z, Yin Z, Cao Y

Drug Design, Development and Therapy 2024, 18:2203-2213

Published Date: 12 June 2024

Integrating Network Pharmacology and Experimental Validation to Decipher the Mechanism of Action of Astragalus–Atractylodes Herb Pair in Treating Hepatocellular Carcinoma

Liang Y, Xie Y, Liu X, Yu L, Yan H, Shang Z, Wu Y, Cai X, Shi W, Du J, Yang Z

Drug Design, Development and Therapy 2024, 18:2169-2187

Published Date: 11 June 2024

Endocannabinoid Hydrolase Inhibitors: Potential Novel Anxiolytic Drugs

Zhao H, Liu Y, Cai N, Liao X, Tang L, Wang Y

Drug Design, Development and Therapy 2024, 18:2143-2167

Published Date: 11 June 2024

Intravenous Odatroltide for Acute Ischemic Stroke Within 24 Hours of Onset: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

Chao AC, Lee TH, Pettigrew LC, Hannawi Y, Huang HY, Chi NF, Chan L, Chen PL, Devlin T

Drug Design, Development and Therapy 2024, 18:2033-2042

Published Date: 6 June 2024

Focus on Trabectedin in Ovarian Cancer: What Do We Still Need to Know?

Boccia SM, Sassu CM, Ergasti R, Vertechy L, Apostol AI, Palluzzi E, Fagotti A, Scambia G, Marchetti C

Drug Design, Development and Therapy 2024, 18:2021-2032

Published Date: 7 June 2024

Analysis of Clinical Trials Using Anti-Tumor Traditional Chinese Medicine Monomers

Lv D, Liu Y, Tang R, Fu S, Kong S, Liao Q, Li H, Lin L

Drug Design, Development and Therapy 2024, 18:1997-2020

Published Date: 5 June 2024

Unveiling the Pharmacological Mechanisms of Davidiin’s Anti-Diabetic Efficacy in Streptozotocin-Treated Rats: A Comprehensive Analysis of Serum Metabolome

Li M, Zhou X, Huang D, Zhao Y, Chen J, Dong Z, Chen W, Zhang F, Sun L

Drug Design, Development and Therapy 2024, 18:1981-1996

Published Date: 5 June 2024

Promising Ursolic Acid as a Novel Antituberculosis Agent: Current Progress and Challenges

Pitaloka DAE, Syaputri Y, Nurlilasari P, Khairunnisa SF, Saallah S

Drug Design, Development and Therapy 2024, 18:1969-1979

Published Date: 31 May 2024

Physicochemistry, Nutritional, and Therapeutic Potential of Ficus carica – A Promising Nutraceutical

Fazel MF, Abu IF, Mohamad MHN, Mat Daud NA, Hasan AN, Aboo Bakkar Z, Md Khir MAN, Juliana N, Das S, Mohd Razali MR, Zainal Baharin NH, Ismail AA

Drug Design, Development and Therapy 2024, 18:1947-1968

Published Date: 30 May 2024

Influences of Propofol, Ciprofol and Remimazolam on Dreaming During Anesthesia for Gastrointestinal Endoscopy: A Randomized Double-Blind Parallel-Design Trial

Zhou R, Fu L, Liu S, Gao S, Zhao Z, Jiang W, Liu L, Ren W, Xiang D, You X, Tang C, Zhou Y, Song Y, Xie J, Xie L, Yu R, Zhang X, Zhou D, Han J, Xia L, Xiong L

Drug Design, Development and Therapy 2024, 18:1907-1915

Published Date: 29 May 2024

Neurovascular Adverse Effects of Sars-Cov-2 Vaccination

Panos LD, Bargiotas P, Hadjigeorgiou G, Panos GD

Drug Design, Development and Therapy 2024, 18:1891-1905

Published Date: 30 May 2024

Shen’ge Formula Protects Cardiac Function in Rats with Pressure Overload-Induced Heart Failure

Qiu B, Qiao S, Shi X, Shen L, Deng B, Ma Z, Zhou D, Wei Y

Drug Design, Development and Therapy 2024, 18:1875-1890

Published Date: 30 May 2024

Evaluation of Drug-Drug Interaction Between Henagliflozin and Hydrochlorothiazide in Healthy Chinese Volunteers

Chen Q, Yu C, Wu Q, Song R, Liu Y, Feng S, Yu C, Jia J

Drug Design, Development and Therapy 2024, 18:1855-1864

Published Date: 29 May 2024

Parabacteroides distasonis-Derived Outer Membrane Vesicles Enhance Antitumor Immunity Against Colon Tumors by Modulating CXCL10 and CD8+ T Cells

Liang R, Li P, Yang N, Xiao X, Gong J, Zhang X, Bai Y, Chen Y, Xie Z, Liao Q

Drug Design, Development and Therapy 2024, 18:1833-1853

Published Date: 28 May 2024

Assessing the Impact of Morphine on Adverse Outcomes in ACS Patients Treated with P2Y12 Inhibitors: Insights from Multiple Real-World Evidence

Ouyang C, Meng C, Li F, Nie S, Gong L, Cao Y, Yuan H, Feng Z

Drug Design, Development and Therapy 2024, 18:1811-1819

Published Date: 27 May 2024

Dexmedetomidine’s Effects on the Livers and Kidneys of Rats with Pancreatic Ischemia-Reperfusion Injury

Bostancı H, Erel S, Küçük A, Kip G, Sezen ŞC, Gokgoz S, Atlı M, Aktepe F, Dikmen K, Arslan M, Kavutçu M

Drug Design, Development and Therapy 2024, 18:1785-1797

Published Date: 27 May 2024

Population Pharmacokinetic Models of Venetoclax in Hematologic Malignancies: A Systematic Review

Zhao Y, Guo N, Zhu Y, Shang J, Chen J, Luo X, Liu Y, Zhang X, Huang L

Drug Design, Development and Therapy 2024, 18:1771-1784

Published Date: 27 May 2024

Imrecoxib: Advances in Pharmacology and Therapeutics

Wang YH, Zhu LL, Li TL, Zhou Q

Drug Design, Development and Therapy 2024, 18:1711-1725

Published Date: 22 May 2024

Pristimerin Exerts Pharmacological Effects Through Multiple Signaling Pathways: A Comprehensive Review

Sun J, Tian Z, Wu J, Li J, Wang Q, Huang S, Wang M

Drug Design, Development and Therapy 2024, 18:1673-1694

Published Date: 18 May 2024

Integrated Approaches Revealed the Therapeutic Mechanisms of Zuojin Pill Against Gastric Mucosa Injury in a Rat Model with Chronic Atrophic Gastritis

Chen L, He T, Wang R, Liu H, Wang X, Li H, Jing M, Zhou X, Wei S, Zou W, Zhao Y

Drug Design, Development and Therapy 2024, 18:1651-1672

Published Date: 17 May 2024

A Comprehensive Update of Anti-COVID-19 Activity of Heterocyclic Compounds

Nazir MS, Ahmad M, Aslam S, Rafiq A, Al-Hussain SA, Zaki MEA

Drug Design, Development and Therapy 2024, 18:1547-1571

Published Date: 8 May 2024

A Novel Tetramethylpyrazine Chalcone Hybrid- HCTMPPK, as a Potential Anti-Lung Cancer Agent by Downregulating MELK

Ma Y, Cui Q, Zhu W, Wang M, Zhai L, Hu W, Liu D, Liu M, Li Y, Li M, Han W

Drug Design, Development and Therapy 2024, 18:1531-1546

Published Date: 7 May 2024

ED-71 Improves Bone Mass in Ovariectomized Rats by Inhibiting Osteoclastogenesis Through EphrinB2-EphB4-RANKL/OPG Axis

Wang K, Kou Y, Rong X, Wei L, Li J, Liu H, Li M, Song H

Drug Design, Development and Therapy 2024, 18:1515-1528

Published Date: 6 May 2024

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