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OncoTargets and Therapy
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Archive: Volume 14, 2021
Alectinib Together with Intracranial Therapies Improved Survival Outcomes in Untreated ALK-Positive Patients with Non-Small-Cell Lung Cancer and Symptomatic and Synchronic Brain Metastases: A Retrospective Study
Yin Q, Li P, Wang P, Zhang Z, Liu Q, Sun Z, Li W, Ma L, Wang X
OncoTargets and Therapy 2021, 14:5533-5542
Published Date: 30 December 2021
Clinical Evaluation of Ramucirumab for the Treatment of Hepatocellular Carcinoma (HCC): Place in Therapy
Choucair K, Kamran S, Saeed A
OncoTargets and Therapy 2021, 14:5521-5532
Published Date: 29 December 2021
Targeted Treatment of Chronic Lymphocytic Leukemia: Clinical Utility of Acalabrutinib
Vitale C, Gibbons JL, Ferrajoli A
OncoTargets and Therapy 2021, 14:5507-5519
Published Date: 29 December 2021
AATF is Overexpressed in Human Bladder Cancer and Regulates Chemo-Sensitivity Through Survivin
Tan S, Fu L, Dong Q
OncoTargets and Therapy 2021, 14:5493-5505
Published Date: 29 December 2021
CBX7, a Potential Prognostic Biomarker in Lung Adenocarcinoma
Yang Y, Hu Z, Sun H, Yu Q, Yang L, Yin F, Sun Y, Pu L, Zhu X, Li S, Chen X, Zhao Y
OncoTargets and Therapy 2021, 14:5477-5492
Published Date: 24 December 2021
Clinical Impact of Switching to Ceritinib After Severe AEs Related to Crizotinib/Alectinib in a Novel PTH2R-ALK Fusion Lung Adenocarcinoma: A Case Report
Shen G, Du Y, Shen J, Zhang J, Xia X, Huang M, Shen W
OncoTargets and Therapy 2021, 14:5471-5475
Published Date: 23 December 2021
Overexpressed Long Noncoding RNA TUG1 Affects the Cell Cycle, Proliferation, and Apoptosis of Pancreatic Cancer Partly Through Suppressing RND3 and MT2A [Retraction]
Hui B, Xu Y, Zhao B, Ji H, Ma Z, Xu S, He Z, Wang K, Lu J
OncoTargets and Therapy 2021, 14:5469-5470
Published Date: 23 December 2021
Identification of NUTF2 as a Candidate Diagnostic and Prognostic Biomarker Associated with Immune Infiltration in Head and Neck Squamous Cell Carcinoma
Zhang R, Gao Y
OncoTargets and Therapy 2021, 14:5455-5467
Published Date: 22 December 2021
Complete Response to PD-1 Inhibitor in Primary Hepatocellular Carcinoma Patients Post-Progression on Bi-Specific Antibody Conjugated CIK Cell Treatment: A Report of Two Cases
Wu T, Zhang L, Zeng Z, Yan T, Cheng J, Miao X, Lu Y
OncoTargets and Therapy 2021, 14:5447-5453
Published Date: 18 December 2021
High Red Cell Distribution Width Independently Predicts Adverse Survival in Patients with Newly Diagnosed Skull Base Chordoma
Li M, Shen Y, Xiong Y, Bai J, Wang S, Li C, Zhang Y
OncoTargets and Therapy 2021, 14:5435-5445
Published Date: 11 December 2021
Effective Disease Control After Combinatorial Treatment with a PD-1 Antibody and an mTOR Inhibitor for Recurrent Ovarian Clear Cell Carcinomas: A Case Report and Literature Review
Li Y, Liu W, Yue X, Fang Y, Zhang X, Zhang X, He Q, Fu N, Wang S, Ma T, Li D
OncoTargets and Therapy 2021, 14:5429-5434
Published Date: 9 December 2021
Efficient Everolimus Treatment for Metastatic Castration Resistant Prostate Cancer with AKT1 Mutation: A Case Report
Yu Z, Wei W, Liu H, Pan E, Yang P, Jiang K
OncoTargets and Therapy 2021, 14:5423-5428
Published Date: 8 December 2021
LncRNA SNHG16 Regulates the Progress of Acute Myeloid Leukemia Through miR183-5p–FOXO1 Axis [Retraction]
Yang R, Ma D, Wu Y, Zhang Y, Zhang L
OncoTargets and Therapy 2021, 14:5421-5422
Published Date: 7 December 2021
Hsa_circ_0006916 Knockdown Represses the Development of Hepatocellular Carcinoma via Modulating miR-599/SRSF2 Axis [Retraction]
Zhu Z, Shen S, Zhao S, Wang Z
OncoTargets and Therapy 2021, 14:5419-5420
Published Date: 7 December 2021
Promotion of miR-221-5p on the Sensitivity of Gastric Cancer Cells to Cisplatin and Its Effects on Cell Proliferation and Apoptosis by Regulating DDR1 [Retraction]
Jiang X, Jiang M, Guo S, Cai P, Wang W, Li Y
OncoTargets and Therapy 2021, 14:5417-5418
Published Date: 7 December 2021
Fibrinogen/Albumin Ratio (FAR) in Patients with Triple Negative Breast Cancer and Its Relationship with Epidermal Growth Factor Receptor Expression
Gao W, Li M, Zhang Y
OncoTargets and Therapy 2021, 14:5403-5415
Published Date: 7 December 2021
M2-Type Macrophages Induce Tregs Generation by Activating the TGF-β/Smad Signalling Pathway to Promote Colorectal Cancer Development
Ma X, Gao Y, Chen Y, Liu J, Yang C, Bao C, Wang Y, Feng Y, Song X, Qiao S
OncoTargets and Therapy 2021, 14:5391-5402
Published Date: 7 December 2021
Efficacy and Drug Resistance Analysis of ALK Inhibitors in Combination with Stereotactic Body Radiation Therapy for Treating Lung Squamous Carcinoma Patient Harboring EML4-ALK Rearrangement
Liang L, Mao M, Wu L, Chen T, Lyu J, Wang Q, Li T
OncoTargets and Therapy 2021, 14:5385-5389
Published Date: 3 December 2021
Identification and Validation a Necroptosis‑related Prognostic Signature and Associated Regulatory Axis in Stomach Adenocarcinoma
Wang N, Liu D
OncoTargets and Therapy 2021, 14:5373-5383
Published Date: 2 December 2021
Endostar Plus Apatinib Successfully Achieved Long Term Progression-Free Survival in Refractory Ovarian Cancer: A Case Report and Literature Review
Xiao C, Xu F, Wang R, Liang Q, Shen K, Xu J, Liu L
OncoTargets and Therapy 2021, 14:5363-5372
Published Date: 1 December 2021
Expression of B7-H3 Correlates with PD-L1 and Poor Prognosis in Patients with Cervical Cancer [Corrigendum]
Zhang Q, Zong L, Zhang H, Xie W, Yang F, Sun W, Cui B, Zhang Y
OncoTargets and Therapy 2021, 14:5361-5362
Published Date: 30 November 2021
Favorable Response to Olaparib in a Patient with Cancer of Unknown Primary Carrying a Germline BRCA1 R71K Mutation
Jia X, Zhao S, Li X, Lv L, Chen X, Pan E, Ou Q, Song C, Sun S, Zhao J, Xu L, Li M
OncoTargets and Therapy 2021, 14:5353-5360
Published Date: 27 November 2021
Durable Response to Vemurafenib and Cobimetinib for the Treatment of BRAF-Mutated Metastatic Melanoma in Routine Clinical Practice
Álamo MC, Ochenduszko S, Crespo G, Corral M, Oramas J, Sancho P, Medina J, Garicano F, López P, Campos Balea B, Rodríguez Garzotto A, Muñoz-Couselo E
OncoTargets and Therapy 2021, 14:5345-5352
Published Date: 27 November 2021
The Controversial Role of Polyploidy in Hepatocellular Carcinoma
Wang N, Hao F, Shi Y, Wang J
OncoTargets and Therapy 2021, 14:5335-5344
Published Date: 27 November 2021
Dehydrocorydaline Inhibits Cell Proliferation, Migration and Invasion via Suppressing MEK1/2-ERK1/2 Cascade in Melanoma [Corrigendum]
Hu H, Dong Z, Wang X, Bai L, Lei Q, Yang J, Li L, Li Q, Liu L, Zhang Y, Ji Y, Guo L, Liu Y, Cui H
OncoTargets and Therapy 2021, 14:5333-5334
Published Date: 23 November 2021
Targeted Treatment of Non-Small Cell Lung Cancer: Focus on Capmatinib with Companion Diagnostics
Guo MZ, Marrone KA, Spira A, Waterhouse DM, Scott SC
OncoTargets and Therapy 2021, 14:5321-5331
Published Date: 23 November 2021
Efficacy with Trastuzumab Deruxtecan for Non-Small-Cell Lung Cancer Harboring HER2 Exon 20 Insertion Mutation in a Patient with a Poor Performance Status: A Case Report
Kato Y, Kato Y, Minegishi Y, Suzuki T, Nakamichi S, Matsumoto M, Miyanaga A, Noro R, Kubota K, Terasaki Y, Seike M, Gemma A
OncoTargets and Therapy 2021, 14:5315-5319
Published Date: 23 November 2021
Immunotherapy-Related Cardiotoxicity Re-Emergence in Non-Small Cell Lung Cancer – A Case Report
Li Y, Hu Y, Yang B, Jin C, Ren H, Wu J, Wang Z, Wei Y, Yang L, Hu Y
OncoTargets and Therapy 2021, 14:5309-5314
Published Date: 23 November 2021
HER2 Amplification in Advanced NSCLC Patients After Progression on EGFR-TKI and Clinical Response to EGFR-TKI Plus Pyrotinib Combination Therapy
Gan J, Huang Y, Liao J, Pang L, Fang W
OncoTargets and Therapy 2021, 14:5297-5307
Published Date: 18 November 2021
Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation [Corrigendum]
Sun J, Shen D, Gao Y, Zheng Y, Zhao L, Maa M, Liu H, Chen X
OncoTargets and Therapy 2021, 14:5295-5296
Published Date: 16 November 2021
Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation [Corrigendum]
Wang S, Wang T, Wang L, Zhong L, Li K
OncoTargets and Therapy 2021, 14:5293-5294
Published Date: 16 November 2021
Potential Biomarkers for the Efficacy of PD-1-PD-L Blockade in Cancer
Grecea M, Soritau O, Dulf D, Ciuleanu TE, Zdrenghea M
OncoTargets and Therapy 2021, 14:5275-5291
Published Date: 17 November 2021
The Study of Mucosal-Associated Invariant T Cells in Colon Cancer and Roles in Immune Activities
Mo J, Zheng L, Gao Z, Wu J, Bao Y
OncoTargets and Therapy 2021, 14:5263-5273
Published Date: 16 November 2021
Circular RNA SMARCA5 Inhibits the Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer by miR-19b-3p/HOXA9 Axis [Retraction]
Wang Y, Li H, Lu H, Qin Y
OncoTargets and Therapy 2021, 14:5261-5262
Published Date: 15 November 2021
Cytochrome 4Z1 Expression is Associated with Poor Prognosis in Colon Cancer Patients
Al-saraireh YM, Alshammari FOFO, youssef AMM, Al-Sarayreh S, Almuhaisen GH, Alnawaiseh N, Al-Shuneigat JM, Alrawashdeh HM
OncoTargets and Therapy 2021, 14:5249-5260
Published Date: 12 November 2021
AATF is Overexpressed in Human Head and Neck Squamous Cell Carcinoma and Regulates STAT3/Survivin Signaling
Fu L, Jin Q, Dong Q, Li Q
OncoTargets and Therapy 2021, 14:5237-5248
Published Date: 9 November 2021
Anti-γ-Aminobutyric Acid Type β Receptor Antibody-Associated Encephalitis After 2 Cycles of Durvalumab Therapy in a Patient with Small Cell Lung Cancer: A Case Report
Li J, Jiang J, Lv J, Zhang R, Chen W, Li S, Jin Q, Wang G
OncoTargets and Therapy 2021, 14:5227-5236
Published Date: 3 November 2021
Long-Term Survival After Salvage Thoracic Surgery on a Patient with ALK-Rearranged Metastatic Lung Adenocarcinoma After Progression on Targeted Therapy
Ren K, Ding G, Xie S, Yang L
OncoTargets and Therapy 2021, 14:5221-5225
Published Date: 2 November 2021
Targeting Endoglin Expressing Cells in the Tumor Microenvironment Does Not Inhibit Tumor Growth in a Pancreatic Cancer Mouse Model
Schoonderwoerd MJ, Hakuno SK, Sassen M, Kuhlemaijer EB, Paauwe M, Slingerland M, Fransen MF, Hawinkels LJ
OncoTargets and Therapy 2021, 14:5205-5220
Published Date: 29 October 2021
MRD-Negative Remission Induced in EP300-ZNF384 Positive B-ALL Patients by Tandem CD19/CD22 CAR T-Cell Therapy Bridging to Allogeneic Stem Cell Transplantation
Zhang XY, Dai HP, Zhang L, Liu SN, Dai Y, Wu DP, Tang XW
OncoTargets and Therapy 2021, 14:5197-5204
Published Date: 29 October 2021
Identification of HOXD10 as a Marker of Poor Prognosis in Glioblastoma Multiforme
Li Y, Ma K, Xie Q, Zhang X, Zhang X, Chen K, Kong L, Qian R
OncoTargets and Therapy 2021, 14:5183-5195
Published Date: 27 October 2021
Comparative Transcriptome Provides a Systematic Perspective on Epstein–Barr Virus-Associated Gastric Carcinoma Cell Lines
Huang JT, Chen JN, Bi YH, Gong LP, Zhang JY, DU Y, Shao CK
OncoTargets and Therapy 2021, 14:5169-5182
Published Date: 23 October 2021
Clinical Utility of Olaparib in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Review of Current Evidence and Patient Selection [Corrigendum]
LeVee A, Lin CY, Posadas E, Figlin R, Bhowmick NA, Di Vizio D, Ellis L, Rosser CJ, Freeman MR, Theodorescu D, Freedland SJ, Gong J
OncoTargets and Therapy 2021, 14:5167-5168
Published Date: 26 October 2021
ALK Rearrangement in Small-Cell Lung Cancer and Durable Response to Alectinib: A Case Report
Sun N, Zhuang Y, Zhang J, Chen S, Dai Y, Guo R
OncoTargets and Therapy 2021, 14:5161-5166
Published Date: 24 October 2021
Targeted Therapy for Advanced or Metastatic Cholangiocarcinoma: Focus on the Clinical Potential of Infigratinib
Yu J, Mahipal A, Kim R
OncoTargets and Therapy 2021, 14:5145-5160
Published Date: 23 October 2021
18β-Glycyrrhetinic Acid Has Anti-Cancer Effects via Inducing Apoptosis and G2/M Cell Cycle Arrest, and Inhibiting Migration of A549 Lung Cancer Cells
Luo YH, Wang C, Xu WT, Zhang Y, Zhang T, Xue H, Li YN, Fu ZR, Wang Y, Jin CH
OncoTargets and Therapy 2021, 14:5131-5144
Published Date: 22 October 2021
Interaction of Gut Microbiome and Host microRNAs with the Occurrence of Colorectal and Breast Cancer and Their Impact on Patient Immunity
De Silva S, Tennekoon KH, Karunanayake EH
OncoTargets and Therapy 2021, 14:5115-5129
Published Date: 22 October 2021
Feasibility and Safety of Neoadjuvant Alectinib in Pulmonary Invasive Mucinous Adenocarcinoma with ALK Rearrangement: Case Report and Literature Review
Gu R, Shi Z, Duan T, Song M
OncoTargets and Therapy 2021, 14:5107-5113
Published Date: 21 October 2021
Serum Reactive Oxygen Species Modulator 1 as a Novel Predictive Biomarker for Resected Lung Adenocarcinoma: A Retrospective Pilot Study
Chang B, Hwang IK, Lee SH
OncoTargets and Therapy 2021, 14:5097-5106
Published Date: 21 October 2021
LncRNA NEAT1 Promotes Proliferation, Migration and Invasion via Regulating miR-296-5p/CNN2 Axis in Hepatocellular Carcinoma Cells [Retraction]
Li Y, Ding X, Xiu S, Du G, Liu Y
OncoTargets and Therapy 2021, 14:5095-5096
Published Date: 21 October 2021
Clinical Application of Tumor Vascular Disrupting Therapy: A Systematic Review and Meta-Analysis
Tsang W, Gan L, Zhang Z, Li T, Luo Y, Zhong L, Huang Y
OncoTargets and Therapy 2021, 14:5085-5093
Published Date: 20 October 2021
A Immune-Related Signature Associated with TME Can Serve as a Potential Biomarker for Survival and Sorafenib Resistance in Liver Cancer
Ju M, Jiang L, Wei Q, Yu L, Chen L, Wang Y, Hu B, Qian P, Zhang M, Zhou C, Li Z, Wei M, Zhao L, Han J
OncoTargets and Therapy 2021, 14:5065-5083
Published Date: 20 October 2021
Long Noncoding RNA LINC00525 Promotes the Aggressive Phenotype of Chordoma Through Acting as a microRNA-505-3p Sponge and Consequently Raising HMGB1 Expression [Expression of Concern]
Li L, Lv G, Wang B, Ma H
OncoTargets and Therapy 2021, 14:5063-5064
Published Date: 20 October 2021
Long Intergenic Non-Protein Coding RNA 519 Promotes the Biological Activities of Tongue Squamous Cell Carcinoma by Sponging microRNA-876-3p and Consequently Upregulating MACC1 [Expression of Concern]
Liu D, Zhao J, Wang H, Li H, Li Y, Qin W
OncoTargets and Therapy 2021, 14:5061-5062
Published Date: 20 October 2021
Long Noncoding RNA ST7-AS1 Upregulates TRPM7 Expression by Sponging microRNA-543 to Promote Cervical Cancer Progression [Expression of Concern]
Qi H, Lu L, Wang L
OncoTargets and Therapy 2021, 14:5059-5060
Published Date: 20 October 2021
Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression [Expression of Concern]
He J, Guan J, Liao S, Wu Z, Liu B, Mo H, Yuan Z
OncoTargets and Therapy 2021, 14:5057-5058
Published Date: 20 October 2021
Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer [Expression of Concern]
Luo X, Yue M, Li C, Sun D, Wang L
OncoTargets and Therapy 2021, 14:5055-5056
Published Date: 20 October 2021
ITPKA1 Promotes Growth, Migration and Invasion of Renal Cell Carcinoma via Activation of mTOR Signaling Pathway [Corrigendum]
Zhu X, Xu A, Zhang Y, Huo N, Cong R, Ma L, Chu Z, Tang Z, Kang X, Xian S, Xu X
OncoTargets and Therapy 2021, 14:5051-5053
Published Date: 15 October 2021
Correlation Between Thymoma and Soluble Interleukin-2 Receptor Expression in a Patient with Good Syndrome
Kitano H, Yamaguchi F, Atarashi K, Hiraiwa M, Shiratori Y, Onozaki S, Shikama Y
OncoTargets and Therapy 2021, 14:5045-5049
Published Date: 12 October 2021
RPARP-AS1/miR125a-5p Axis Promotes Cell Proliferation, Migration and Invasion in Colon Cancer
Ren Y, Zhao C, He Y, Min X, Xu H, Hu X
OncoTargets and Therapy 2021, 14:5035-5043
Published Date: 12 October 2021
First Report of Severe Autoimmune Hemolytic Anemia During Eltrombopag Therapy in Waldenström Macroglobulinemia-Associated Thrombocytopenia
Shen Y, Yu F, Ge H, Shao K, Zhou Y, Ye B, Shen Y, Wu D
OncoTargets and Therapy 2021, 14:5027-5033
Published Date: 9 October 2021
Early Prediction of Objective Response of Fibrinogen in a Real-World Cohort of Hepatocellular Carcinoma Cases Treated by Programmed Cell Death Receptor-1 and Lenvatinib
Shen Y, Wang H, Wei J, Li W
OncoTargets and Therapy 2021, 14:5019-5026
Published Date: 7 October 2021
ET-1 Promotes Epithelial–Mesenchymal Transition in Oral Squamous Cell Carcinoma Cells via the microRNA-489-3p /TWIST Axis
Tzeng HE, Tang CH, Tsai CH, Chiu CH, Wu MH, Yen Y
OncoTargets and Therapy 2021, 14:5005-5018
Published Date: 6 October 2021
Long Noncoding RNA Sox2 Overlapping Transcript (SOX2OT) Promotes Non-Small-Cell Lung Cancer Migration and Invasion via Sponging microRNA 132 (miR-132) [Retraction]
Zhang K, Li Y, Qu L, Ma X, Zhao H, Tang Y
OncoTargets and Therapy 2021, 14:5003-5004
Published Date: 5 October 2021
MicroRNA-939 Directly Targets HDGF to Inhibit the Aggressiveness of Prostate Cancer via Deactivation of the WNT/β-Catenin Pathway [Retraction]
Situ J, Zhang H, Jin Z, Li K, Mao Y, Huang W
OncoTargets and Therapy 2021, 14:5001-5002
Published Date: 5 October 2021
Long Noncoding RNA X-Inactive Specific Transcript Facilitates Cellular Functions in Melanoma via miR-139-5p/ROCK1 Pathway [Retraction]
Tian K, Sun D, Chen M, Yang Y, Wang F, Guo T, Shi Z
OncoTargets and Therapy 2021, 14:4999-5000
Published Date: 5 October 2021
Long Non-Coding RNA HAND2-AS1 Inhibits Growth and Migration of Gastric Cancer Cells Through Regulating the miR-590-3p/KCNT2 Axis [Retraction]
Yu L, Li H, Li Z, Jia J, Wu Z, Wang M, Li F, Feng Z, Xia H, Gao G
OncoTargets and Therapy 2021, 14:4997-4998
Published Date: 4 October 2021
MicroRNA-675 Directly Targets MAPK1 to Suppress the Oncogenicity of Papillary Thyroid Cancer and is Sponged by Long Non-Coding RNA RMRP [Retraction]
Wang J, Xiao T, Zhao M
OncoTargets and Therapy 2021, 14:4995-4996
Published Date: 4 October 2021
SNHG8 is Upregulated in Esophageal Squamous Cell Carcinoma and Directly Sponges microRNA-411 to Increase Oncogenicity by Upregulating KPNA2 [Retraction]
Song H, Song J, Lu L, Li S
OncoTargets and Therapy 2021, 14:4993-4994
Published Date: 4 October 2021
MicroRNA-937 Inhibits the Malignant Phenotypes of Breast Cancer by Directly Targeting and Downregulating Forkhead Box Q1 [Retraction]
Han X, Guo X, Zhang W, Cong Q
OncoTargets and Therapy 2021, 14:4991-4992
Published Date: 4 October 2021
Clinical Significance of ADAMTS19, BMP7, SIM1, and SFRP1 Promoter Methylation in Renal Clear Cell Carcinoma
Kubiliute R, Zalimas A, Bakavicius A, Ulys A, Jankevicius F, Jarmalaite S
OncoTargets and Therapy 2021, 14:4979-4990
Published Date: 5 October 2021
TP53 Co-Mutational Features and NGS-Calibrated Immunohistochemistry Threshold in Gastric Cancer
Yu R, Sun T, Zhang X, Li Z, Xu Y, Liu K, Shi Y, Wu X, Shao Y, Kong L
OncoTargets and Therapy 2021, 14:4967-4978
Published Date: 1 October 2021
MicroRNA-769-5p Inhibits Pancreatic Ductal Adenocarcinoma Progression by Directly Targeting and Downregulating ETS Proto-Oncogene 1 [Retraction]
Cheng K, Feng L, Yu S, Yu C, Chi N
OncoTargets and Therapy 2021, 14:4965-4966
Published Date: 1 October 2021
MicroRNA-618 Directly Targets Metadherin mRNA to Suppress the Malignant Phenotype of Osteosarcoma Cells by Reducing PTEN-AKT Pathway Output [Retraction]
Li B, Zhao J, Zhao Q, Wu D, Zhang C, Zhao K, Song Y, Gao C
OncoTargets and Therapy 2021, 14:4963-4964
Published Date: 1 October 2021
MicroRNA-936 Targets FGF2 to Inhibit Epithelial Ovarian Cancer Aggressiveness by Deactivating the PI3K/Akt Pathway [Retraction]
Li C, Yu S, Wu S, Ni Y, Pan Z
OncoTargets and Therapy 2021, 14:4961-4962
Published Date: 4 October 2021
Efficacy and Toxicity Profile of Carfilzomib-Based Regimens for Treatment of Newly Diagnosed Multiple Myeloma: A Systematic Review
Imtiaz H, Khan M, Ehsan H, Wahab A, Rafae A, Khan AY, Jamil A, Sana MK, Jamal A, Ali TJ, Ansar I, Khan MM, Khouri J, Anwer F
OncoTargets and Therapy 2021, 14:4941-4960
Published Date: 1 October 2021
LINC01224 Exhibits Cancer-Promoting Activity in Epithelial Ovarian Cancer Through microRNA-485-5p-Mediated PAK4 Upregulation [Retraction]
Xing S, Zhang Y, Zhang J
OncoTargets and Therapy 2021, 14:4939-4940
Published Date: 30 September 2021
MicroRNA-761 Targets FGFR1 to Suppress the Malignancy of Osteosarcoma by Deactivating PI3K/Akt Pathway [Retraction]
Lv Z, Ma J, Wang J, Lu J
OncoTargets and Therapy 2021, 14:4937-4938
Published Date: 28 September 2021
MicroRNA-652 Suppresses Malignant Phenotypes in Glioblastoma Multiforme via FOXK1-Mediated AKT/mTOR Signaling Pathway [Retraction]
Yang H, Song Z, Wu X, Wu Y, Liu C
OncoTargets and Therapy 2021, 14:4935-4936
Published Date: 28 September 2021
microRNA-605 Inhibits the Oncogenicity of Non-Small-Cell Lung Cancer by Directly Targeting Forkhead Box P1 [Retraction]
Zhou W, Li R
OncoTargets and Therapy 2021, 14:4933-4934
Published Date: 28 September 2021
A Radiomic Approach to Access Tumor Immune Status by CD8+TRMs on Surgically Resected Non-Small-Cell Lung Cancer
Min J, Dong F, Wu P, Xu X, Wu Y, Tan Y, Yang F, Chai Y
OncoTargets and Therapy 2021, 14:4921-4931
Published Date: 27 September 2021
Identification of a Novel SLC8A1-ALK Fusion and Non-Canonical Expression Significantly Responding to ALK-TKIs in Lung Adenocarcinoma: A Case Report
Zhu X, He Y, Wang Y, Lei Y, Su X, Liu Y, Wu S, He Z
OncoTargets and Therapy 2021, 14:4915-4920
Published Date: 27 September 2021
Bone Marrow Mesenchymal Stem Cells-Derived Exosomal miR-425-5p Inhibits Acute Myeloid Leukemia Cell Proliferation, Apoptosis, Invasion and Migration by Targeting WTAP
Zhang L, Khadka B, Wu J, Feng Y, Long B, Xiao R, Liu J
OncoTargets and Therapy 2021, 14:4901-4914
Published Date: 24 September 2021
MicroRNA-559 Plays an Inhibitory Role in the Malignant Progression of Glioblastoma Cells by Directly Targeting Metadherin [Retraction]
Yang F, Zhang C, Xu C, Fu F, Han D, Li H
OncoTargets and Therapy 2021, 14:4899-4900
Published Date: 24 September 2021
microRNA-564 Inhibits the Aggressive Phenotypes of Papillary Thyroid Cancer by Directly Targeting Astrocyte-Elevated Gene-1 [Retraction]
Song Z, Yang H, Wu X, Kong C, Xu C
OncoTargets and Therapy 2021, 14:4897-4898
Published Date: 24 September 2021
Multimodal Treatment Combining Salvage Surgery-Assisted Chemotherapy and Checkpoints Blockade Immunotherapy Achieves Complete Remission on a Recurrent Penile Cancer Patient: A Case Report
Hu L, Shan X, Han D, Guo Z, Wang H, Xiao Z
OncoTargets and Therapy 2021, 14:4891-4896
Published Date: 22 September 2021
Raloxifene Protects Cisplatin-Induced Renal Injury in Mice via Inhibiting Oxidative Stress
An JH, Li CY, Chen CY, Wu JB, Shen H
OncoTargets and Therapy 2021, 14:4879-4890
Published Date: 22 September 2021
Elevated RGMA Expression Predicts Poor Prognosis in Patients with Glioblastoma
Phan TL, Kim HJ, Lee SJ, Choi MC, Kim SH
OncoTargets and Therapy 2021, 14:4867-4878
Published Date: 21 September 2021
Study on Efficacy and Safety of Low-Dose Apatinib Combined with Camrelizumab and SOX Regimen as First-Line Treatment of Locally Advanced and Unresectable Gastric/Gastroesophageal Junction Cancer: A Protocol for an Open-Label, Dose Escalation and Extension Phase Ib Clinical Trial
Wang KX, Cui TY, Yang XD, Wang GQ, Jiang QS, Sun H, Jiang NY, Yong XM, Shi CB, Ding YB, Chen XF, Fang YY
OncoTargets and Therapy 2021, 14:4859-4865
Published Date: 21 September 2021
Rapid Response to Pembrolizumab in a Chemo-Refractory Testicular Germ Cell Cancer with Microsatellite Instability-High
Kawai K, Tawada A, Onozawa M, Inoue T, Sakurai H, Mori I, Takiguchi Y, Miyazaki J
OncoTargets and Therapy 2021, 14:4853-4858
Published Date: 21 September 2021
microRNA-769 is Downregulated in Colorectal Cancer and Inhibits Cancer Progression by Directly Targeting Cyclin-Dependent Kinase 1 [Retraction]
Wang L, Xu M, Lu P, Zhou F
OncoTargets and Therapy 2021, 14:4851-4852
Published Date: 19 September 2021
miRNA-641 Inhibits the Proliferation, Migration, and Invasion and Induces Apoptosis of Cervical Cancer Cells by Directly Targeting ZEB1 [Retraction]
Yao R, Zheng H, Wu L, Cai P
OncoTargets and Therapy 2021, 14:4849-4850
Published Date: 19 September 2021
microRNA-628 Inhibits the Proliferation of Acute Myeloid Leukemia Cells by Directly Targeting IGF-1R [Retraction]
Chen L, Jiang X, Chen H, Han Q, Liu C, Sun M
OncoTargets and Therapy 2021, 14:4847-4848
Published Date: 19 September 2021
Roles of N6‐Methyladenosine Demethylase FTO in Malignant Tumors Progression
Zheng QK, Ma C, ullah I, Hu K, Ma RJ, Zhang N, Sun ZG
OncoTargets and Therapy 2021, 14:4837-4846
Published Date: 16 September 2021
A Metastatic Cervical Adenocarcinoma Patient Carrying HER2 G292R Achieved Complete Response Upon Pyrotinib Treatment
Liu J, Zhuo Y, Wang F, Li Z, Lin Y, Li L, Pan J, Song Y, Du H, Li C, Xu Q
OncoTargets and Therapy 2021, 14:4833-4836
Published Date: 16 September 2021
Clinical Utility of Olaparib in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Review of Current Evidence and Patient Selection
LeVee A, Lin CY, Posadas E, Figlin R, Bhowmick NA, Di Vizio D, Ellis L, Rosser CJ, Freeman MR, Theodorescu D, Freedland SJ, Gong J
OncoTargets and Therapy 2021, 14:4819-4832
Published Date: 15 September 2021
High Tumor Mutation Burden and DNA Repair Gene Mutations are Associated with Primary Resistance to Crizotinib in ALK-Rearranged Lung Cancer
Xiao D, Deng Q, He D, Huang Y, Liang W, Wang F, Yang H
OncoTargets and Therapy 2021, 14:4809-4817
Published Date: 15 September 2021
Clinical and Pathologic Complete Response to Gefitinib in a Patient with SqCLC Harboring EGFR p.E746_S752delinsV Mutation
Zhuang W, Zhang C, Tang Y, Tian D, Lan Z, Zeng C, Qiao G
OncoTargets and Therapy 2021, 14:4805-4808
Published Date: 15 September 2021
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells
Chen W, Wu S, Huang Y, Zhang T, Dong H, Zheng X, Chen T, Gong X, Liu G, Zhao X
OncoTargets and Therapy 2021, 14:4791-4804
Published Date: 10 September 2021
CircPTCH1 Promotes Migration in Lung Cancer by Regulating MYCN Expression Through miR-34c-5p
Shen Z, Sun S
OncoTargets and Therapy 2021, 14:4779-4789
Published Date: 10 September 2021
TFF-1 Functions to Suppress Multiple Phenotypes Associated with Lung Cancer Progression
Minegishi K, Dobashi Y, Tsubochi H, Hagiwara K, Ishibashi Y, Nomura S, Nakamura R, Ohmoto Y, Endo S
OncoTargets and Therapy 2021, 14:4761-4777
Published Date: 10 September 2021
Carbon-Ion Beam Irradiation and the miR-200c Mimic Effectively Eradicate Pancreatic Cancer Stem Cells Under in vitro and in vivo Conditions
Sai S, Kim EH, Koom WS, Vares G, Suzuki M, Yamada S, Hayashi M
OncoTargets and Therapy 2021, 14:4749-4760
Published Date: 16 September 2021
LncRNA SNHG16 Drives Proliferation and Invasion of Papillary Thyroid Cancer Through Modulation of miR-497 [Retraction]
Wen Q, Zhao L, Wang T, Lv N, Cheng X, Zhang G, Bai L
OncoTargets and Therapy 2021, 14:4747-4748
Published Date: 9 September 2021
microRNA-612 Suppresses the Malignant Development of Non-Small-Cell Lung Cancer by Directly Targeting Bromodomain-Containing Protein 4 [Retraction]
Kang X, Kong F, Wu S, Liu Q, Yang C, Wu X, Zhang W
OncoTargets and Therapy 2021, 14:4745-4746
Published Date: 9 September 2021
Long Non-Coding RNA ASB16-AS1 Functions as a miR-760 Sponge to Facilitate the Malignant Phenotype of Osteosarcoma by Increasing HDGF Expression [Retraction]
Yin R, Liu J, Zhao D, Wang F
OncoTargets and Therapy 2021, 14:4743-4744
Published Date: 9 September 2021
Long Noncoding RNA SNHG7, a Molecular Sponge for microRNA-485, Promotes the Aggressive Behavior of Cervical Cancer by Regulating PAK4 [Retraction]
Wu F, Sui Y, Wang Y, Xu T, Fan L, Zhu H
OncoTargets and Therapy 2021, 14:4741-4742
Published Date: 9 September 2021
microRNA-605 Directly Targets SOX9 to Alleviate the Aggressive Phenotypes of Glioblastoma Multiforme Cell Lines by Deactivating the PI3K/Akt Pathway [Retraction]
Jia J, Wang J, Yin M, Liu Y
OncoTargets and Therapy 2021, 14:4739-4740
Published Date: 9 September 2021
microRNA-493 Inhibits Tongue Squamous Cell Carcinoma Oncogenicity via Directly Targeting HMGA2 [Retraction]
Jiao D, Liu Y, Tian Z
OncoTargets and Therapy 2021, 14:4737-4738
Published Date: 9 September 2021
Long Noncoding RNA DLEU1 Aggravates Glioma Progression via the miR-421/MEF2D Axis [Retraction]
Feng L, He M, Rao M, Diao J, Zhu Y
OncoTargets and Therapy 2021, 14:4735-4736
Published Date: 9 September 2021
Identification and Experimental Validation of Immune-Associate lncRNAs for Predicting Prognosis in Cervical Cancer
Ye J, Chen X, Lu W
OncoTargets and Therapy 2021, 14:4721-4734
Published Date: 7 September 2021
Identification of microRNA Signature and Key Genes Between Adenoma and Adenocarcinomas Using Bioinformatics Analysis
Shi X, Gao GY, Shen J
OncoTargets and Therapy 2021, 14:4707-4720
Published Date: 4 September 2021
miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma [Retraction]
Zong S, Zhao J, Liu L
OncoTargets and Therapy 2021, 14:4705-4706
Published Date: 6 September 2021
Long Non-Coding RNA Duxap8 Facilitates Cell Proliferation and Induces Apoptosis in Colorectal Cancer via miR-519b/ZNF277 Axis
Liang H, Wang J, Zhang P, Yang W, Yang Y, Zhi Y, Wu W, Dong X
OncoTargets and Therapy 2021, 14:4693-4703
Published Date: 1 September 2021
Testing for EGFR Mutations and ALK Rearrangements in Advanced Non-Small-Cell Lung Cancer: Considerations for Countries in Emerging Markets
Dalurzo ML, Avilés-Salas A, Soares FA, Hou Y, Li Y, Stroganova A, Öz B, Abdillah A, Wan H, Choi YL
OncoTargets and Therapy 2021, 14:4671-4692
Published Date: 1 September 2021
Occurrence, Related Factors and Prognostic Value of Vascular Lake in Hepatocellular Carcinoma Patients Treated with Drug-Eluting Bead Transarterial Chemoembolization
Li H, Wang M, Chen P, Li F, Kuang D, Han X, Ren J, Duan X
OncoTargets and Therapy 2021, 14:4659-4670
Published Date: 31 August 2021
A Preliminary Study on the Pathogenesis of Colorectal Cancer by Constructing a Hsa-circRNA-0067835-miRNA-mRNA Regulatory Network
Liu N, Jiang F, Chen Z
OncoTargets and Therapy 2021, 14:4645-4658
Published Date: 31 August 2021
ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer [Corrigendum]
Weng M, Zhang H, Hou W, Sun Z, Zhong J, Miao C
OncoTargets and Therapy 2021, 14:4641-4643
Published Date: 31 August 2021
Effect of Long Non-Coding RNA AOC4P on Gastrointestinal Stromal Tumor Cells [Retraction]
Hu JC, Wang Q, Jiang LX, Cai L, Zhai HY, Yao ZW, Zhang ML, Feng Y
OncoTargets and Therapy 2021, 14:4639-4640
Published Date: 30 August 2021
MicroRNA-200b Acts as a Tumor Suppressor in Osteosarcoma via Targeting ZEB1 [Retraction]
Li Y, Zeng C, Tu M, Jiang W, Dai Z, Hu Y, Deng Z, Xiao W
OncoTargets and Therapy 2021, 14:4637-4638
Published Date: 30 August 2021
circPDSS1 Stimulates the Development of Colorectal Cancer via Activating the Wnt/β-Catenin Signaling [Retraction]
Fang Q, Yang A, Dong A, Zhao L
OncoTargets and Therapy 2021, 14:4635-4636
Published Date: 30 August 2021
Diagnosis of NUT Carcinoma Despite False-Negative Next-Generation Sequencing Results: A Case Report and Literature Review
Wang X, Wang J, Luo X, Lu J, Wang L, Li Q, Wang EH
OncoTargets and Therapy 2021, 14:4621-4633
Published Date: 27 August 2021
Daam1 Overexpression Promotes Gastric Cancer Progression and Regulates ERK and AKT Signaling Pathways
Zhang Y, Bai X, Zhang Y, Li Y
OncoTargets and Therapy 2021, 14:4609-4619
Published Date: 27 August 2021
A Case Report of Targeted Therapy with Anlotinib in a Patient with Advanced Breast Metaplastic Carcinoma
Zou J, Yang X, Duan J, Wang J, Yang Z, Luo D, Liu L, Chen J, Nie J
OncoTargets and Therapy 2021, 14:4599-4607
Published Date: 27 August 2021
Osimertinib in EGFR-Mutated Lung Cancer: A Review of the Existing and Emerging Clinical Data
Lee CS, Milone M, Seetharamu N
OncoTargets and Therapy 2021, 14:4579-4597
Published Date: 26 August 2021
Surgical Resection of Pancreatic Hepatoid Carcinoma Followed by Combined Transarterial Chemoembolization and Immunotherapy: A Case Report
He J, Zhao Q, Liu Q, Li F, He L, Liu M, Yan X
OncoTargets and Therapy 2021, 14:4575-4578
Published Date: 26 August 2021
A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer
Liu S, Li D, Liu J, Wang H, Horecny I, Shen R, Zhang R, Wu H, Hu Q, Zhao P, Zhang F, Yan Y, Feng J, Zhuang L, Li J, Zhang L, Tao W
OncoTargets and Therapy 2021, 14:4561-4574
Published Date: 24 August 2021
Simultaneous Follicular Lymphoma and Myelofibrosis: Report of a Case with Review of the Literature
Kong L, Li J, Wang RC, Kang L, Wei Q, Li Y
OncoTargets and Therapy 2021, 14:4551-4559
Published Date: 24 August 2021
Potential Role of Pleural Fluid Cytokine Profile in Myelomatous Pleural Effusions
Xu J, Gao L, Yan M, Wang B, Song Z, Liu H, Sun K, Nong L, Wang M, Cen X
OncoTargets and Therapy 2021, 14:4545-4550
Published Date: 24 August 2021
Undifferentiated Small Round Cell Sarcoma of the Postcricoid Region of the Hypopharynx: A Rare Case Report and Review of the Literature
Zhu J, Li B, Hu JJ, Liu W, Lu D, Liu J
OncoTargets and Therapy 2021, 14:4537-4544
Published Date: 24 August 2021
Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells
Tsai SC, Wu WC, Yang JS
OncoTargets and Therapy 2021, 14:4523-4536
Published Date: 21 August 2021
Clinical Utility of Fedratinib in Myelofibrosis
Waksal JA, Tremblay D, Mascarenhas J
OncoTargets and Therapy 2021, 14:4509-4521
Published Date: 21 August 2021
Efficacy and Safety of Apatinib for Elderly Patients with Advanced or Metastatic Gastric Cancer After Failure of at Least First-Line Chemotherapy: A Multi-Center, Single-Arm, Phase II Study
Ren D, Wang G, Zhang Y, Kan J, Dong Q, Zhao J, Ji F, Li H, Luo Y, Lin M, Li G, Liu Z, Ma X, Guo Q, Zhao F, Shen G, Zhao J
OncoTargets and Therapy 2021, 14:4499-4508
Published Date: 18 August 2021
Endometrial Tumors with MSI-H and dMMR Share a Similar Tumor Immune Microenvironment
Song Y, Gu Y, Hu X, Wang M, He Q, Li Y
OncoTargets and Therapy 2021, 14:4485-4497
Published Date: 16 August 2021
Advances in Immunotherapy of Malignant Pleural Mesothelioma
Liao D, Yu Y, Mei Q, Wang Z, Li X, Jia Y, Kong F
OncoTargets and Therapy 2021, 14:4477-4484
Published Date: 14 August 2021
Prognostic Value of miR-1826 in Prostate Cancer and Its Regulatory Effect on Tumor Progression
Liu Y, Liu J, Han X, Mou L
OncoTargets and Therapy 2021, 14:4467-4475
Published Date: 13 August 2021
A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer
Qu Z, Liu J, Zhu L, Zhou Q
OncoTargets and Therapy 2021, 14:4451-4465
Published Date: 12 August 2021
Subgroup Analysis by Liver Metastasis in the FRESCO Trial Comparing Fruquintinib versus Placebo Plus Best Supportive Care in Chinese Patients with Metastatic Colorectal Cancer
Qin S, Xu RH, Shen L, Xu J, Bai Y, Yang L, Deng Y, Chen ZD, Zhong H, Pan H, Guo W, Shu Y, Yuan Y, Zhou J, Xu N, Liu T, Ma D, Wu C, Cheng Y, Chen D, Li W, Sun S, Yu Z, Cao P, Chen H, Wang J, Wang S, Wang H, Wang N, Zhang B, Zhang Q, Su W, Guo X, Li J
OncoTargets and Therapy 2021, 14:4439-4450
Published Date: 11 August 2021
TP53 Mutation Related and Directly Regulated lncRNA Prognosis Markers in Hepatocellular Carcinoma
Zhang X, Fu Z, Zhang X
OncoTargets and Therapy 2021, 14:4427-4437
Published Date: 10 August 2021
Long Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis
Zhang M, Zhu W, Haeryfar M, Jiang S, Jiang X, Chen W, Li J
OncoTargets and Therapy 2021, 14:4415-4426
Published Date: 10 August 2021
Choriocarcinoma Masquerading as Lung Abscess or Lung Cancer: A Case with Atypical Imaging Findings
Gu Q, Yan S, Lin J, Wu X, Chen L, Gan M, Luo H, Lv D, Lin L
OncoTargets and Therapy 2021, 14:4407-4414
Published Date: 10 August 2021
High Matrix Metalloproteinase 28 Expression is Associated with Poor Prognosis in Pancreatic Adenocarcinoma
Liu N, Zhong L, Ni G, Lin J, Xie L, Li T, Dan H, Chen Q
OncoTargets and Therapy 2021, 14:4391-4406
Published Date: 10 August 2021
Targeting c-MET to Enhance the Efficacy of Olaparib in Prostate Cancer
Wang Z, Dai Z, Wang B, Gao Y, Gao X, Wang L, Zhou S, Yang L, Qiu X, Liu Z
OncoTargets and Therapy 2021, 14:4383-4389
Published Date: 4 August 2021
Rapidly Evolving Treatment Landscape for Metastatic Esophagogastric Carcinoma: Review of Recent Data
Kankeu Fonkoua LA, Yoon HH
OncoTargets and Therapy 2021, 14:4361-4381
Published Date: 5 August 2021
The Anti-Cancer Effect of Four Curcumin Analogues on Human Glioma Cells
Luo SM, Wu YP, Huang LC, Huang SM, Hueng DY
OncoTargets and Therapy 2021, 14:4345-4359
Published Date: 4 August 2021
miR-765 Acts as a Tumor Promoter and Indicates Poor Prognosis in Non-Small Cell Lung Cancer
Wang J, Wang L, Zhang C
OncoTargets and Therapy 2021, 14:4335-4343
Published Date: 4 August 2021
Acquired ALK Resistance Mutations Identified from Liquid Biopsy in an ALK-Rearranged Squamous Cell Lung Cancer Patient Treated with Sequential ALK TKI Therapy: A Case Report
Yao B, Han X, Pang L, Xu C, Liu S, Cheng X, Chen J
OncoTargets and Therapy 2021, 14:4329-4333
Published Date: 3 August 2021
Immunotherapy-Related Cystitis: Case Report and Review of the Literature
Zhu L, Wang Z, Stebbing J, Wang Z, Peng L
OncoTargets and Therapy 2021, 14:4321-4328
Published Date: 31 July 2021
LncRNA MIR205HG Drives Esophageal Squamous Cell Carcinoma Progression by Regulating miR-214/SOX4 Axis [Corrigendum]
Li H, Jia J, Yang L, Chu J, Sheng J, Wang C, Meng W, Jia Z, Yin H, Wan J, He F
OncoTargets and Therapy 2021, 14:4319-4320
Published Date: 2 August 2021
Glypican-1 Overexpression in Different Types of Breast Cancers
Alshammari FO, Al-Saraireh YM, Youssef AM, AL-sarayra YM, Alrawashdeh HM
OncoTargets and Therapy 2021, 14:4309-4318
Published Date: 30 July 2021
Sorafenib in the Treatment of Virus-Related HCC: Differences Between HCV and HBV
De Matteis S, Ghetti M, Gramantieri L, Marisi G, Casadei-Gardini A
OncoTargets and Therapy 2021, 14:4305-4308
Published Date: 30 July 2021
Gallbladder Adenosquamous Cancer with Situs Inversus Totalis: A Case Report and Literature Review
Huang J, Yang H, Wang M, Zhao X, Shao S, Zhang F, Que R, Hu Q, Liang T
OncoTargets and Therapy 2021, 14:4299-4304
Published Date: 28 July 2021
LINC00152 Promotes the Growth and Invasion of Oral Squamous Cell Carcinoma by Regulating miR-139-5p [Retraction]
Li M, Ning J, Li Z, Wang J, Zhao C, Wang L
OncoTargets and Therapy 2021, 14:4297-4298
Published Date: 29 July 2021
SQLE Mediates Metabolic Reprogramming to Promote LN Metastasis in Castration-Resistant Prostate Cancer
Xu Z, Huang L, Dai T, Pei X, Xia L, Zeng G, Ye M, Liu K, Zeng F, Han W, Jiang S
OncoTargets and Therapy 2021, 14:4285-4295
Published Date: 24 July 2021
Expression of B7-H3 Correlates with PD-L1 and Poor Prognosis in Patients with Cervical Cancer
Zhang Q, Zong L, Zhang H, Xie W, Yang F, Sun W, Cui B, Zhang Y
OncoTargets and Therapy 2021, 14:4275-4283
Published Date: 23 July 2021
Heterochronous Metastases of Lung Adenocarcinoma to Pancreas and Liver: A Case Report from Pathological Perspectives
Zhang B, Hu Q, Yu J, Wang J, Yang H, Lou J, Cai G, Huang H, Xu M, Xiao Z, Zhang Y
OncoTargets and Therapy 2021, 14:4269-4273
Published Date: 22 July 2021
Long Noncoding RNA RGMB-AS1 Acts as a microRNA-574 Sponge Thereby Enhancing the Aggressiveness of Gastric Cancer via HDAC4 Upregulation [Retraction]
Wang X, Chen X, Tian Y, Jiang D, Song Y
OncoTargets and Therapy 2021, 14:4267-4268
Published Date: 22 July 2021
NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma
Li D, Yang D, Cui S, Pan E, Yang P, Dai Z
OncoTargets and Therapy 2021, 14:4261-4265
Published Date: 21 July 2021
Perirenal Perivascular Epithelioid Cell Tumor (PEcoma) with Pulmonary Micro Invasive Adenocarcinoma: A Case Report and Literature Review
Li Z, Hu N, Liao Y, Liu J
OncoTargets and Therapy 2021, 14:4255-4260
Published Date: 21 July 2021
ILT4 in Colorectal Cancer Cells Induces Suppressive T Cell Contexture and Disease Progression
Yang Z, Gao A, Shi W, Wang J, Zhang X, Xu Z, Xu T, Zheng Y, Sun Y, Yang F
OncoTargets and Therapy 2021, 14:4239-4254
Published Date: 20 July 2021
A Case of Pulmonary Embolism with Sarcomatoid Malignant Pleural Mesothelioma with Long-Term Pleural Effusion
Gu R, Jiang L, Duan T, Chen C, Wu S, Mu D
OncoTargets and Therapy 2021, 14:4231-4237
Published Date: 16 July 2021
The Regulatory Role of PRRX1 in Cancer Epithelial-Mesenchymal Transition
Du W, Liu X, Yang M, Wang W, Sun J
OncoTargets and Therapy 2021, 14:4223-4229
Published Date: 16 July 2021
CDH11 Regulates Adhesion and Transcellular Migration of Tongue Squamous Cell Carcinoma
Zheng BT, Li QL, Lan T, Xie J, Lu YG, Zheng DL, Su BH
OncoTargets and Therapy 2021, 14:4211-4222
Published Date: 16 July 2021
Complete Pathologic Response of Multiple Liver Metastases and Clinical Complete Response of Rectal Cancer in a Patient with Ataxia-Telangiectasia Mutated Gene Mutations After XELOXIRI Plus Bevacizumab: A Case Report
Cheng Y, Wu G, Zhang S, Liu Y, Qu J, Qu X
OncoTargets and Therapy 2021, 14:4201-4209
Published Date: 15 July 2021
Expression and Diagnostic Value of tRNA-Derived Fragments Secreted by Extracellular Vesicles in Hypopharyngeal Carcinoma
Xi J, Zeng Z, Li X, Zhang X, Xu J
OncoTargets and Therapy 2021, 14:4189-4199
Published Date: 14 July 2021
The Emerging Role of Circ-SHPRH in Cancer
Ju X, Tang Y, Qu R, Hao S
OncoTargets and Therapy 2021, 14:4177-4188
Published Date: 13 July 2021
Key Role of MCUR1 in Malignant Progression of Breast Cancer
Gao P, Peng T, Lin S, Zhi W, Cao C, Wu P, Xi L, Wu P, Yang Q, Ding W
OncoTargets and Therapy 2021, 14:4163-4175
Published Date: 13 July 2021
Recent Advances in Systemic Treatments for HER-2 Positive Advanced Gastric Cancer
Kahraman S, Yalcin S
OncoTargets and Therapy 2021, 14:4149-4162
Published Date: 13 July 2021
Preoperative Serum Hypersensitive-c-Reactive-Protein (Hs-CRP) to Albumin Ratio Predicts Survival in Patients with Luminal B Subtype Breast Cancer
Liu X, Guo X, Zhang Z
OncoTargets and Therapy 2021, 14:4137-4148
Published Date: 9 July 2021
The Role and Mechanism of MALAT1 Long Non-Coding RNA in the Diagnosis and Treatment of Head and Neck Squamous Cell Carcinoma
Ye D, Deng Y, Shen Z
OncoTargets and Therapy 2021, 14:4127-4136
Published Date: 8 July 2021
Primary Synchronous Ipsilateral Renal Fibrosarcoma and Renal Pelvic Carcinoma: A Case Report and Literature Review
Jiang H, Liu L, Li G
OncoTargets and Therapy 2021, 14:4119-4125
Published Date: 7 July 2021
FSTL3 is a Prognostic Biomarker in Gastric Cancer and is Correlated with M2 Macrophage Infiltration
Liu YJ, Li JP, Zhang Y, Nie MJ, Zhang YH, Liu SL, Zou X
OncoTargets and Therapy 2021, 14:4099-4117
Published Date: 6 July 2021
Progress in Treatment of Non-Small Cell Lung Cancer Harboring HER2 Aberrations
Ni J, Zhang L
OncoTargets and Therapy 2021, 14:4087-4098
Published Date: 6 July 2021
A Comparative Study of Self-Expandable Metallic Stent Combined with Double 125I Seeds Strands or Single 125I Seeds Strand in the Treatment of Advanced Perihilar Cholangiocarcinoma with Malignant Obstructive Jaundice
Li Z, Jiao D, Han X, Liu Z
OncoTargets and Therapy 2021, 14:4077-4086
Published Date: 6 July 2021
Chidamide-Induced Accumulation of Reactive Oxygen Species Increases Lenalidomide Sensitivity Against Multiple Myeloma Cells
Jiang D, Zhang K, Zhu Y, Zhu Y, Zou L, Hu J, Cui Y, Zhou W, Chen F, He Y
OncoTargets and Therapy 2021, 14:4061-4075
Published Date: 6 July 2021
A Novel Biological Activity of the STAT3 Inhibitor Stattic in Inhibiting Glutathione Reductase and Suppressing the Tumorigenicity of Human Cervical Cancer Cells via a ROS-Dependent Pathway
Xia Y, Wang G, Jiang M, Liu X, Zhao Y, Song Y, Jiang B, Zhu D, Hu L, Zhang Z, Cao T, Wang JM, Hu J
OncoTargets and Therapy 2021, 14:4047-4060
Published Date: 5 July 2021
Expression and Clinical Value of LncRNA GAPLINC in Esophageal Squamous Cell Carcinoma
Wang P, Yang S, Dai S, Ni Q, Liu H, Yu L, Lu K, Han G, Huang J
OncoTargets and Therapy 2021, 14:4039-4045
Published Date: 5 July 2021
Anti-CD22 CAR-T Cell Therapy as a Salvage Treatment in B Cell Malignancies Refractory or Relapsed After Anti-CD19 CAR-T therapy
Zhu H, Deng H, Mu J, Lyu C, Jiang Y, Deng Q
OncoTargets and Therapy 2021, 14:4023-4037
Published Date: 2 July 2021
Circular RNAs Regulate Glucose Metabolism in Cancer Cells
Ji X, Sun W, Lv C, Huang J, Zhang H
OncoTargets and Therapy 2021, 14:4005-4021
Published Date: 2 July 2021
Knockdown of LINC00504 Inhibits the Proliferation and Invasion of Breast Cancer via the Downregulation of miR-140-5p
Hou T, Ye L, Wu S
OncoTargets and Therapy 2021, 14:3991-4003
Published Date: 2 July 2021
Sustained Clinical Benefit of Pyrotinib Combined with Capecitabine Rescue Therapy After Trastuzumab Resistance in HER2-Positive Advanced Gastric Cancer: A Case Report
Li X, Gu X, Xu J, Chen L, Li H, Meng D, Bai H, Yang J, Qian J
OncoTargets and Therapy 2021, 14:3983-3989
Published Date: 1 July 2021
Demographic Characteristics and Treatment Patterns Among Patients Receiving Palbociclib for HR+/HER2− Advanced Breast Cancer: A Nationwide Real-World Experience
Boér K, Rubovszky G, Rokszin G, Abonyi-Tóth Z, Földesi C, Dank M
OncoTargets and Therapy 2021, 14:3971-3981
Published Date: 1 July 2021
The Association Between Radioiodine Refractory in Papillary Thyroid Carcinoma, Sodium/Iodide Symporter Expression, and BRAFV600E Mutation
Anekpuritanang T, Uataya M, Claimon A, Laokulrath N, Pongsapich W, Pithuksurachai P
OncoTargets and Therapy 2021, 14:3959-3969
Published Date: 29 June 2021
Durable Response to Crizotinib in a Patient with Pulmonary Adenocarcinoma Harboring MET Intron 14 Mutation: A Case Report
Leyrat B, Durando X, Veyssiere H, Bernadach M
OncoTargets and Therapy 2021, 14:3949-3958
Published Date: 29 June 2021
Intravascular Papillary Endothelial Hyperplasia Mimicking Vaginal Malignant Tumor in a Post-Radiotherapy Patient: A Case Report and Literature Review
Gong YX, Xie Y, Chen L, Sui L
OncoTargets and Therapy 2021, 14:3945-3948
Published Date: 29 June 2021
Nuclear Factor-Kappa B1 Inhibits Early Apoptosis of Glioma Cells by Promoting the Expression of Bcl-2 [Retraction]
Yang TQ, Chen M, Wang YQ, Xu W, Han Y, Xu J, Xiang YJ, Yuan B, Wang HZ, Zhou YX
OncoTargets and Therapy 2021, 14:3943-3944
Published Date: 29 June 2021
Fatty Acid–Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway
Wu Z, Jeong JH, Ren C, Yang L, Ding L, Li F, Jiang D, Zhu Y, Lu J
OncoTargets and Therapy 2021, 14:3929-3942
Published Date: 29 June 2021
PD-L1 Expressing Recurrent Clear Cell Carcinoma of the Vulva with Durable Partial Response to Pembrolizumab: A Case Report
Sachdeva M, Ngoi NY, Lim D, Poon ML, Thian YL, Lim YW, Lim SE, Tong P, Lum JH, Ng J, Ilancheran A, Domingo EJ, Low JJ, Tan DSP
OncoTargets and Therapy 2021, 14:3921-3928
Published Date: 29 June 2021
Bioinformatics Analysis of Choriocarcinoma-Related MicroRNA-Transcription Factor-Target Gene Regulatory Networks and Validation of Key miRNAs
Peng X, Zhang Z, Mo Y, Liu J, Wang S, Liu H
OncoTargets and Therapy 2021, 14:3903-3919
Published Date: 29 June 2021
Remarkable Response to Olaparib in a Patient with Combined Hepatocellular-Cholangiocarcinoma Harboring a Biallelic BRCA2 Mutation
Su YL, Ng CT, Jan YH, Hsieh YL, Wu CL, Tan KT
OncoTargets and Therapy 2021, 14:3895-3901
Published Date: 29 June 2021
RETRACTED ARTICLE: HS3ST2 and Its Related Molecules as Potential Biomarkers for Predicting Lymph Node Metastasis in Patients with Colorectal Cancer
Gao G, Shi X, Shen J
OncoTargets and Therapy 2021, 14:3881-3894
Published Date: 25 June 2021
Complete Response of Hepatocellular Carcinoma with Macroscopic Vascular Invasion and Pulmonary Metastasis to the Combination of Drug-Eluting Beads Transarterial Chemoembolization and Huaier Granule: A Case Report
Zhou TY, Tao GF, Chen SQ, Wang HL, Zhang YL, Zhou GH, Nie CH, Zhu TY, Wang BQ, Yu ZN, Jing L, Chen F, Sun JH
OncoTargets and Therapy 2021, 14:3873-3880
Published Date: 23 June 2021
Down-Regulation of an Autophagy-Related Gene SERPINA1 as a Superior Prognosis Biomarker Associates with Relapse and Distant Metastasis in Colon Adenocarcinoma
Fu C, Yu Z, He Y, Ding J, Wei M
OncoTargets and Therapy 2021, 14:3861-3872
Published Date: 22 June 2021
Celastrol Modulates Multiple Signaling Pathways to Inhibit Proliferation of Pancreatic Cancer via DDIT3 and ATF3 Up-Regulation and RRM2 and MCM4 Down-Regulation
Youns M, Askoura M, Abbas HA, Attia GH, Khayyat AN, Goda RM, Almalki AJ, Khafagy ES, Hegazy WAH
OncoTargets and Therapy 2021, 14:3849-3860
Published Date: 23 June 2021
Identification of Enzalutamide Resistance-Related circRNA-miRNA-mRNA Regulatory Networks in Patients with Prostate Cancer
Yu J, Sun S, Mao W, Xu B, Chen M
OncoTargets and Therapy 2021, 14:3833-3848
Published Date: 21 June 2021
Expression Profiles of Circular RNAs in Human Papillary Thyroid Carcinoma Based on RNA Deep Sequencing
Lv C, Sun W, Huang J, Qin Y, Ji X, Zhang H
OncoTargets and Therapy 2021, 14:3821-3832
Published Date: 21 June 2021
Identification of Phospho-Tyrosine Targets as a Strategy for the Treatment of Esophageal Adenocarcinoma Cells
Lee J, Chen R, Mohanakumar T, Bremner R, Mittal S, Fleming TP
OncoTargets and Therapy 2021, 14:3813-3820
Published Date: 21 June 2021
Cholesterol Metabolism as a Potential Therapeutic Target and a Prognostic Biomarker for Cancer Immunotherapy
Zhang H, Zhao W, Li X, He Y
OncoTargets and Therapy 2021, 14:3803-3812
Published Date: 21 June 2021
A New Treatment Strategy for Early T‐Cell Precursor Acute Lymphoblastic Leukemia: A Case Report and Literature Review
Mao J, Xue L, Wang H, Zhu Y, Wang J, Zhao L
OncoTargets and Therapy 2021, 14:3795-3802
Published Date: 18 June 2021
Epigenetic Mechanism of Enrichment of A549 Lung Cancer Stem Cells with 5-Fu
Cao F, Shi M, Yu B, Cheng X, Li X, Jia X
OncoTargets and Therapy 2021, 14:3783-3794
Published Date: 18 June 2021
Bergamottin Induces DNA Damage and Inhibits Malignant Progression in Melanoma by Modulating miR-145/Cyclin D1 Axis
Zhao Z, Liao N
OncoTargets and Therapy 2021, 14:3769-3781
Published Date: 17 June 2021
Progesterone Receptor Together with PKCα Expression as Prognostic Factors for Astrocytomas Malignancy
Arcos-Montoya D, Wegman-Ostrosky T, Mejía-Pérez S, De la Fuente-Granada M, Camacho-Arroyo I, García-Carrancá A, Velasco-Velázquez MA, Manjarrez-Marmolejo J, González-Arenas A
OncoTargets and Therapy 2021, 14:3757-3768
Published Date: 16 June 2021
m6A-Induced LncRNA MEG3 Suppresses the Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cell Through miR-544b/BTG2 Signaling
Wu J, Pang R, Li M, Chen B, Huang J, Zhu Y
OncoTargets and Therapy 2021, 14:3745-3755
Published Date: 15 June 2021
A Novel KIF5B-EGFR Fusion Variant in Non-Small-Cell Lung Cancer and Response to Afatinib: A Case Report
Wang X, Huang L, Cai J, Liu A
OncoTargets and Therapy 2021, 14:3739-3744
Published Date: 14 June 2021
miR-593-3p Promotes Proliferation and Invasion in Prostate Cancer Cells by Targeting ADIPOR1
Huang Q, Peng L, Sun Y, Huang J, Han T, Li Y, Peng H
OncoTargets and Therapy 2021, 14:3729-3737
Published Date: 14 June 2021
G9a Regulates Cell Sensitivity to Radiotherapy via Histone H3 Lysine 9 Trimethylation and CCDC8 in Lung Cancer
Li Y, Chen Z, Cao K, Zhang L, Ma Y, Yu S, Jin H, Liu X, Li W
OncoTargets and Therapy 2021, 14:3721-3728
Published Date: 10 June 2021
Current Perspectives and Novel Strategies of NRAS-Mutant Melanoma
Garcia-Alvarez A, Ortiz C, Muñoz-Couselo E
OncoTargets and Therapy 2021, 14:3709-3719
Published Date: 9 June 2021
Durable Clinical Response to Immune and Targeted Therapies in an Elderly Man with Synchronous Gastric (HER2+) and Bladder Cancers: Case Report and Literature Review
Tian X, Zhu Q, Zhang Z
OncoTargets and Therapy 2021, 14:3701-3708
Published Date: 9 June 2021
miR-210-3p Promotes Lung Cancer Development and Progression by Modulating USF1 and PCGF3
Chen Q, Zhang H, Zhang J, Shen L, Yang J, Wang Y, Ma J, Zhuan B
OncoTargets and Therapy 2021, 14:3687-3700
Published Date: 9 June 2021
circHIPK3 (hsa_circ_0000284) Promotes Proliferation, Migration and Invasion of Breast Cancer Cells via miR-326
Qi L, Sun B, Yang B, Lu S
OncoTargets and Therapy 2021, 14:3671-3685
Published Date: 9 June 2021
Construction and Analysis of a circRNA-Mediated ceRNA Network in Lung Adenocarcinoma
Wang Z, Pei H, Liang H, Zhang Q, Wei L, Shi D, Chen Y, Zhang J
OncoTargets and Therapy 2021, 14:3659-3669
Published Date: 8 June 2021
miR-183-5p Promotes HCC Migration/Invasion via Increasing Aerobic Glycolysis
Niu Y, Liu F, Wang X, Chang Y, Song Y, Chu H, Bao S, Chen C
OncoTargets and Therapy 2021, 14:3649-3658
Published Date: 4 June 2021
miR-340 Promotes Retinoblastoma Cell Proliferation, Migration and Invasion Through Targeting WIF1
Li K, Han F, Wu Y, Wang X
OncoTargets and Therapy 2021, 14:3635-3648
Published Date: 4 June 2021
Identification of Susceptible Genes for Chronic Obstructive Pulmonary Disease with Lung Adenocarcinoma by Weighted Gene Co-Expression Network Analysis
Li P, Wang Y, Wang X, Liu L, Chen L
OncoTargets and Therapy 2021, 14:3625-3634
Published Date: 4 June 2021
Identification of Ten Mitosis Genes Associated with Tamoxifen Resistance in Breast Cancer
Sun X, Ding S, Lu S, Wang Z, Chen X, Shen K
OncoTargets and Therapy 2021, 14:3611-3624
Published Date: 4 June 2021
β-Elemene Enhances the Sensitivity of Osteosarcoma Cells to Doxorubicin via Downregulation of Peroxiredoxin-1
Zhang S, Guo W
OncoTargets and Therapy 2021, 14:3599-3609
Published Date: 3 June 2021
miR-622 Suppresses Tumor Formation by Directly Targeting VEGFA in Papillary Thyroid Carcinoma [Retraction]
Wang R, Ma Q, Ji L, Yao Y, Ma M, Wen Q
OncoTargets and Therapy 2021, 14:3597-3598
Published Date: 3 June 2021
ITGA2 Overexpression Promotes Esophageal Squamous Cell Carcinoma Aggression via FAK/AKT Signaling Pathway
Huang W, Zhu J, Shi H, Wu Q, Zhang C
OncoTargets and Therapy 2021, 14:3583-3596
Published Date: 3 June 2021
Targeted-Gene Sequencing and Bioinformatics Analysis of Patients with Pancreatic Mucoepidermoid Carcinoma: A Case Report and Literature Review
Chen Z, Zhang L, Huang J, Ding C, Zhang T, Wan D, Xue L
OncoTargets and Therapy 2021, 14:3567-3581
Published Date: 3 June 2021
LncRNA PVT1 Facilitates Proliferation, Migration and Invasion of NSCLC Cells via miR-551b/FGFR1 Axis
Wang X, Cheng Z, Dai L, Jiang T, Li P, Jia L, Jing X, An L, Liu M, Wu S, Wang Y
OncoTargets and Therapy 2021, 14:3555-3565
Published Date: 2 June 2021
Dysregulation of Zinc Finger Protein 395 Contributes to the Pathogenesis of Chondrosarcoma
Chen C, Zhou H, Liu Z, Ma X
OncoTargets and Therapy 2021, 14:3545-3553
Published Date: 1 June 2021
Near Complete Pathologic Response to PD-1 Inhibitor and Radiotherapy in a Patient with Locally Advanced Pancreatic Ductal Adenocarcinoma
McCarthy PM, Rendo MJ, Uy MD, Adams AM, O'Shea AE, Nelson DW, Fenderson JL, Cebe KM, Krell RW, Clifton GT, Peoples GE, Vreeland TJ
OncoTargets and Therapy 2021, 14:3537-3544
Published Date: 1 June 2021
LINC00665 Promotes the Progression of Multiple Myeloma by Adsorbing miR-214-3p and Positively Regulating the Expression of PSMD10 and ASF1B [Retraction]
Wang C, Li M, Wang S, Jiang Z, Liu Y
OncoTargets and Therapy 2021, 14:3535-3536
Published Date: 1 June 2021
Comparative Analysis and in vitro Experiments of Signatures and Prognostic Value of Immune Checkpoint Genes in Colorectal Cancer
Ma R, Qu X, Che X, Yang B, Li C, Hou K, Guo T, Xiao J, Liu Y
OncoTargets and Therapy 2021, 14:3517-3534
Published Date: 31 May 2021
Development and Validation of an Autophagy-Stroma-Based Microenvironment Gene Signature for Risk Stratification in Colorectal Cancer
Chen L, Zhang K, Sun J, Tang J, Zhou J
OncoTargets and Therapy 2021, 14:3503-3515
Published Date: 31 May 2021
Acetone Extract of Cornus officinalis Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling
Xu R, Zeng M, Wu Y, Wang S, Zhang B, Zhang J, Kan Y, Li B, Cao B, Zheng X, Feng W
OncoTargets and Therapy 2021, 14:3487-3501
Published Date: 28 May 2021
Androgen Deprivation Therapy for Patients with Androgen-Receptor-Positive Metastatic Salivary Duct Carcinoma: A Case Report and Review of the Literature
You Y, Wang P, Wan X, Xu L, Gong Y, Zhang W
OncoTargets and Therapy 2021, 14:3481-3486
Published Date: 28 May 2021
Silencing HIPPI Suppresses Tumor Progression in Non-Small-Cell Lung Cancer by Inhibiting DNA Replication
Xie G, Li Y, Jiang Y, Ye X, Tang J, Chen J
OncoTargets and Therapy 2021, 14:3467-3480
Published Date: 27 May 2021
Clinical Significance of the D-Loop Gene Mutation in Mitochondrial DNA in Laryngeal Cancer
Wang L, Cheng HX, Zhou YH, Ma M
OncoTargets and Therapy 2021, 14:3461-3466
Published Date: 26 May 2021
Targeted Sequencing Facilitated Diagnosis of an Uncommon Patient Harboring Both Multiple Primary and Intrapulmonary Metastatic Lung Cancer: A Case Report
Li H, Dong S, Zhang D, Guo Z, Li C, Xiang J, Zou X, Yan L, Sun Y, Li W
OncoTargets and Therapy 2021, 14:3455-3459
Published Date: 26 May 2021
NUSAP1 Accelerates Osteosarcoma Cell Proliferation and Cell Cycle Progression via Upregulating CDC20 and Cyclin A2
Wang H, Liu Z, Wu P, Wang H, Ren W
OncoTargets and Therapy 2021, 14:3443-3454
Published Date: 25 May 2021
Preparation, Biocompatibility and Antitumor Activity of Nanodelivery System Targeting Breast Cancer Base on a Silica Nanoparticle
Liu J, Ren S, Zhang X, Feng Y, Qiu Z, Ma L, Huang J
OncoTargets and Therapy 2021, 14:3429-3442
Published Date: 25 May 2021
Platelets: The Emerging Clinical Diagnostics and Therapy Selection of Cancer Liquid Biopsies
Meng Y, Sun J, Zheng Y, Zhang G, Yu T, Piao H
OncoTargets and Therapy 2021, 14:3417-3428
Published Date: 25 May 2021
Successful Treatment with Ensartinib After Alectinib-induced Hyperbilirubinemia in ALK-Positive NSCLC
Peng L, Xiao K, Cui J, Ye XH, Zhang YC, Mao L, Selvaggi G, Yen J, Stebbing J
OncoTargets and Therapy 2021, 14:3409-3415
Published Date: 25 May 2021
LINC00894 Enhances the Progression of Breast Cancer by Sponging miR-429 to Regulate ZEB1 Expression
Meng D, Shao H, Feng C
OncoTargets and Therapy 2021, 14:3395-3407
Published Date: 25 May 2021
SOX17 Antagonizes the WNT Signaling Pathway and is Epigenetically Inactivated in Clear-Cell Renal Cell Carcinoma
Wang L, Wang Z, Zhu Y, Tan S, Chen X, Yang X
OncoTargets and Therapy 2021, 14:3383-3394
Published Date: 24 May 2021
Efficacy and Safety of Systemic and Locoregional Cisplatin Chronotherapy in Rats with Ovarian Carcinoma
Kireeva G, Gubareva E, Maydin M, Osetnik V, Kruglov S, Panchenko A, Dorofeeva A, Tyndyk M, Fedoros E, Anisimov V
OncoTargets and Therapy 2021, 14:3373-3381
Published Date: 24 May 2021
Successful Management of a Patient with Refractory Primary Central Nervous System Lymphoma by Zanubrutinib
Cheng Q, Wang J, Lv C, Xu J
OncoTargets and Therapy 2021, 14:3367-3372
Published Date: 24 May 2021
The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation
Kuang Q, Liang Y, Zhuo Y, Cai Z, Jiang F, Xie J, Zheng Y, Zhong W
OncoTargets and Therapy 2021, 14:3353-3366
Published Date: 24 May 2021
miR-488 Inhibits Cell Growth and Metastasis in Renal Cell Carcinoma by Targeting HMGN5 [Retraction]
Wei X, Yu L, Kong X
OncoTargets and Therapy 2021, 14:3351-3352
Published Date: 20 May 2021
Functions and Targets of miR-335 in Cancer
Ye L, Wang F, Wu H, Yang H, Yang Y, Ma Y, Xue A, Zhu J, Chen M, Wang J, Zhang QA
OncoTargets and Therapy 2021, 14:3335-3349
Published Date: 20 May 2021
Sevoflurane Suppresses Colon Cancer Cell Malignancy by Regulating circ-PI4KA
Sun S, Wang P, Ren L, Wang H, Zhan Y, Shan S
OncoTargets and Therapy 2021, 14:3319-3333
Published Date: 20 May 2021
High Expression of Cyclin D1 is an Independent Marker for Favorable Prognosis in Middle Eastern Breast Cancer
Siraj AK, Parvathareddy SK, Annaiyappanaidu P, Ahmed SO, Siraj N, Tulbah A, Al-Dayel F, Ajarim D, Al-Kuraya KS
OncoTargets and Therapy 2021, 14:3309-3318
Published Date: 19 May 2021
Banxia Xiexin Decoction Inhibits the Expression of PD-L1 Through Multi-Target and Multi-Pathway Regulation of Major Oncogenes in Gastric Cancer
Feng X, Xue F, He G, Huang S, Ni Q
OncoTargets and Therapy 2021, 14:3297-3307
Published Date: 19 May 2021
MiR-144 Suppresses Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Targeting SMAD4 [Retraction]
Yu M, Lin Y, Zhou Y, Jin H, Hou B, Wu Z, Li Z, Jian Z, Sun J
OncoTargets and Therapy 2021, 14:3295-3296
Published Date: 19 May 2021
Circular RNA circWDR27 Promotes Papillary Thyroid Cancer Progression by Regulating miR-215-5p/TRIM44 Axis
Wang W, Huang C, Luo P, Yao J, Li J, Wang W, Liu F
OncoTargets and Therapy 2021, 14:3281-3293
Published Date: 19 May 2021
Artificial Intelligence Based on Blood Biomarkers Including CTCs Predicts Outcomes in Epithelial Ovarian Cancer: A Prospective Study
Ma J, Yang J, Jin Y, Cheng S, Huang S, Zhang N, Wang Y
OncoTargets and Therapy 2021, 14:3267-3280
Published Date: 18 May 2021
Comprehensive Analysis of the Relationship Between Metabolic Reprogramming and Immune Function in Prostate Cancer
Xie W, Guo H, Zhang J, Hu L, Wu Y, Wang X
OncoTargets and Therapy 2021, 14:3251-3266
Published Date: 18 May 2021
MicroRNA-29b-3p Inhibits the Migration and Invasion of Gastric Cancer Cells by Regulating the Autophagy-Associated Protein MAZ
Zhao X, Ye N, Feng X, Ju H, Liu R, Lu W
OncoTargets and Therapy 2021, 14:3239-3249
Published Date: 18 May 2021
Long Noncoding RNA LINC01410 Suppresses Tumorigenesis and Enhances Radiosensitivity in Neuroblastoma Cells Through Regulating miR-545-3p/HK2 Axis
Mou L, Wang L, Zhang S, Wang Q
OncoTargets and Therapy 2021, 14:3225-3238
Published Date: 18 May 2021
LncRNA ST8SIA6-AS1 Promotes Cholangiocarcinoma Progression by Suppressing the miR-145-5p/MAL2 Axis
He J, Yan H, Wei S, Chen G
OncoTargets and Therapy 2021, 14:3209-3223
Published Date: 17 May 2021
Urolithin A Inhibits Epithelial–Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway
Cheng F, Dou J, Zhang Y, Wang X, Wei H, Zhang Z, Cao Y, Wu Z
OncoTargets and Therapy 2021, 14:3199-3208
Published Date: 17 May 2021
Case Report of a Breast Mass with Three Types of Malignant Tumors—Squamous Cell Carcinoma, Invasive Ductal Carcinoma, and Breast Sarcoma
Li C, Fang H, Lu H
OncoTargets and Therapy 2021, 14:3193-3197
Published Date: 14 May 2021
Regional Brain Glucose Metabolism and Its Prognostic Value in Pretreatment Extranodal Natural Killer/T-Cell Lymphoma Patients
Zhou Z, Guo Z, Hu Q, Ding W, Ding C, Tang L
OncoTargets and Therapy 2021, 14:3179-3191
Published Date: 14 May 2021
MiR-502-3P Suppresses Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Targeting SET [Retraction]
Jin H, Yu M, Lin Y, Hou B, Wu Z, Li Z, Sun J
OncoTargets and Therapy 2021, 14:3177-3178
Published Date: 18 May 2021
Diagnosis and Individualized Treatment of Secondary Central Nervous System Lymphoma: A Case Report
Li Q, Liu W, Li K, Tian Y, Li H
OncoTargets and Therapy 2021, 14:3167-3175
Published Date: 13 May 2021
CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway
Cao Y, Xie X, Li M, Gao Y
OncoTargets and Therapy 2021, 14:3151-3165
Published Date: 13 May 2021
Epigenetic Study of Esophageal Carcinoma Based on Methylation, Gene Integration and Weighted Correlation Network Analysis
Xu Y, Wang N, Liu R, Lv H, Li Z, Zhang F, Gai C, Tian Z
OncoTargets and Therapy 2021, 14:3133-3149
Published Date: 13 May 2021
Identification of the EMT-Related Genes Signature for Predicting Occurrence and Progression in Thyroid Cancer
Li Q, Jiang S, Feng T, Zhu T, Qian B
OncoTargets and Therapy 2021, 14:3119-3131
Published Date: 12 May 2021
MiR-17 and miR-93 Promote Tumor Progression by Targeting p21 in Patients with Chordoma
Dong W, Li J, Dong X, Shi W, Zhang Y, Liu Y
OncoTargets and Therapy 2021, 14:3109-3118
Published Date: 12 May 2021
Inhibition of circRNA circVPS33B Reduces Warburg Effect and Tumor Growth Through Regulating the miR-873-5p/HNRNPK Axis in Infiltrative Gastric Cancer
Lu Y, Cheng J, Cai W, Zhuo H, Wu G, Cai J
OncoTargets and Therapy 2021, 14:3095-3108
Published Date: 12 May 2021
Long Noncoding RNA CCDC26 Promotes Thyroid Cancer Malignant Progression via miR-422a/EZH2/Sirt6 Axis
Ma X, Li Y, Song Y, Xu G
OncoTargets and Therapy 2021, 14:3083-3094
Published Date: 11 May 2021
Effect of GLUT1 Inhibition and Autophagy Modulation on the Growth and Migration of Laryngeal Carcinoma Stem Cells Under Hypoxic and Low-Glucose Conditions
Chen XH, Liu J, Zhong JT, Zhou SH, Fan J
OncoTargets and Therapy 2021, 14:3069-3081
Published Date: 11 May 2021
Significant Benefits of Afatinib and Apatinib in a Refractory Advanced NSCLC Patient Resistant to Osimertinib: A Case Report
Zhao Y, Chen Y, Huang H, Li X, Shao L, Ding H
OncoTargets and Therapy 2021, 14:3063-3067
Published Date: 7 May 2021
IFNγ/PD-L1 Signaling Improves the Responsiveness of Anti-PD-1 Therapy in Colorectal Cancer: An in vitro Study
Yuan W, Deng D, Li H, Hu X, Shang X, Hou X, Jiang H, He H
OncoTargets and Therapy 2021, 14:3051-3062
Published Date: 7 May 2021
A Phase I Trial of the MET/ALK/ROS1 Inhibitor Crizotinib Combined with the VEGF Inhibitor Pazopanib in Patients with Advanced Solid Malignancies
Piha-Paul SA, Dumbrava EE, Nair BC, Xiong W, Xu L, Mostorino R, Subbiah V, Tannir N, Fu S, Naing A, Janku F, Karp DD, Patel S, Daw NC, Hong D, Meric-Bernstam F, Zinner R
OncoTargets and Therapy 2021, 14:3037-3049
Published Date: 7 May 2021
Emerging Mechanisms and Treatment Progress on Liver Metastasis of Colorectal Cancer
Zheng W, Wu F, Fu K, Sun G, Sun G, Li X, Jiang W, Cao H, Wang H, Tang W
OncoTargets and Therapy 2021, 14:3013-3036
Published Date: 6 May 2021
A Case of Phyllodes Tumor of the Breast with Mixed Liposarcoma: Case Report and Literature Review
Tu He Ta Mi Shi ME, Wang N, Yao Q, Dong SS, Feng X, Zhao J, Zou H, Pang LJ, Qi Y
OncoTargets and Therapy 2021, 14:3003-3011
Published Date: 6 May 2021
Increased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression
Wang J, Jiang YH, Yang PY, Liu F
OncoTargets and Therapy 2021, 14:2991-3002
Published Date: 5 May 2021
MIIP is Downregulated in Gastric Cancer and Its Forced Expression Inhibits Proliferation and Invasion of Gastric Cancer Cells in vitro and in vivo [Corrigendum]
Sun D, Wang Y, Jiang S, Wang G, Xin Y
OncoTargets and Therapy 2021, 14:2989-2990
Published Date: 6 May 2021
High Expression of SLC41A3 Correlates with Poor Prognosis in Hepatocellular Carcinoma
Li Q, Xiong DL, Wang H, Jin WL, Ma YY, Fan XM
OncoTargets and Therapy 2021, 14:2975-2988
Published Date: 5 May 2021
Treatment Strategies for Metastatic Castration-Sensitive Prostate Cancer: From “All-Comers” to “Personalized” Approach
Harada K, Shiota M, Minato A, Matsumoto M, Tomisaki I, Fujisawa M, Fujimoto N
OncoTargets and Therapy 2021, 14:2967-2974
Published Date: 5 May 2021
Tumor Mutation Burden and Differentially Mutated Genes Among Immune Phenotypes in Patients with Lung Adenocarcinoma
Wang H, Chen S, Meng D, Wu C, Zhu J, Jiang M, Ning J, Wu S, Wu L, Li J, Chen B, Zhao S, Li W, Yu J, Fang Q, Zhu J, Zhao W, He Y, Zhou C
OncoTargets and Therapy 2021, 14:2953-2965
Published Date: 4 May 2021
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma
Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B
OncoTargets and Therapy 2021, 14:2941-2952
Published Date: 4 May 2021
Advances in Therapy for Hormone Receptor (HR)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Advanced Breast Cancer Patients Who Have Experienced Progression After Treatment with CDK4/6 Inhibitors
Li C, Li X
OncoTargets and Therapy 2021, 14:2929-2939
Published Date: 3 May 2021
Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma
Gu W, Chen P, Ren P, Wang Y, Li X, Gong M
OncoTargets and Therapy 2021, 14:2917-2927
Published Date: 30 April 2021
Alectinib for Miliary Lung Metastasis in ALK-Positive Lung Adenocarcinoma
Satoh H, Okuma Y, Kashima J, Konnno-Yamamoto A, Yatabe Y, Ohe Y
OncoTargets and Therapy 2021, 14:2911-2915
Published Date: 30 April 2021
Exploration of the Associations of lncRNA Expression Patterns with Tumor Mutation Burden and Prognosis in Colon Cancer
Ding C, Shan Z, Li M, Xia Y, Jin Z
OncoTargets and Therapy 2021, 14:2893-2909
Published Date: 29 April 2021
MiR-140-3p Impedes Gastric Cancer Progression and Metastasis by Regulating BCL2/BECN1-Mediated Autophagy
Chen J, Cai S, Gu T, Song F, Xue Y, Sun D
OncoTargets and Therapy 2021, 14:2879-2892
Published Date: 29 April 2021
LncRNA EGOT/miR-211-5p Affected Radiosensitivity of Rectal Cancer by Competitively Regulating ErbB4
Li C, Liu H, Wei R, Liu Z, Chen H, Guan X, Zhao Z, Wang X, Jiang Z
OncoTargets and Therapy 2021, 14:2867-2878
Published Date: 28 April 2021
TCEB3 is Regulated by Circ-0000212/miR-140-3p Axis to Promote the Progression of Cervical Cancer
Wang Y, Miao C, Gao X
OncoTargets and Therapy 2021, 14:2853-2865
Published Date: 28 April 2021
Combination of Osimertinib and Anlotinib May Overcome the Resistance Mediated by in cis EGFR T790M-C797S in NSCLC: A Case Report
Zhou R, Song L, Zhang W, Shao L, Li X, Li X
OncoTargets and Therapy 2021, 14:2847-2851
Published Date: 28 April 2021
Genetic Analysis and Targeted Therapy Using Buparlisib and MK2206 in a Patient with Triple Metachronous Cancers of the Kidney, Prostate, and Squamous Cell Carcinoma of the Lung: A Case Report
Zhao T, Tian Y, Ding X, Liu L, Tan B, Yang B, Wu J, Lei T, Wang R, Ding Y
OncoTargets and Therapy 2021, 14:2839-2845
Published Date: 28 April 2021
A Novel Circular RNA circCSPP1 Promotes Liver Cancer Progression by Sponging miR-1182
Jia N, Song Z, Chen B, Cheng J, Zhou W
OncoTargets and Therapy 2021, 14:2829-2838
Published Date: 23 April 2021
EGFR (p. G719A+L747V)/EML4-ALK Co-alterations in Lung Adenocarcinoma with Leptomeningeal Metastasis Responding to Afatinib Treatment: A Case Report
Lu Z, Wang X, Luo Y, Wei J, Zeng Z, Xiong Q, Cai J, Liu A
OncoTargets and Therapy 2021, 14:2823-2828
Published Date: 23 April 2021
Coexistence of Lung Squamous Cell Carcinoma and Pulmonary Tuberculosis Within a Single Lesion: A Case Report [Erratum]
Yu MJ, Li PJ, Liang ZA
OncoTargets and Therapy 2021, 14:2821-2822
Published Date: 23 April 2021
Olaparib Treatment in a Patient with Advanced Gallbladder Cancer Harboring BRCA1 Mutation
Li X, Gao L, Qiu M, Cao D
OncoTargets and Therapy 2021, 14:2815-2819
Published Date: 22 April 2021
Expression Profiles of tRNA-Derived Fragments and Their Potential Roles in Multiple Myeloma
Xu C, Fu Y
OncoTargets and Therapy 2021, 14:2805-2814
Published Date: 22 April 2021
Maintenance Long-Term Multiple Cycles Treatment with Docetaxel in Metastatic Castration-Resistant Prostate Cancer: A Report of Three Cases
Cao JZ, Pan JF, Ng DM, Ying MQ, Jiang JH, Ma Q
OncoTargets and Therapy 2021, 14:2797-2803
Published Date: 21 April 2021
Downregulation of Chemokine CCL20 Involved in Myeloma Cells Resistant to Elotuzumab and Lenalidomide
Wang H, Shi H, He X, Liao A
OncoTargets and Therapy 2021, 14:2789-2795
Published Date: 21 April 2021
Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis
Gao H, Xu J, Qiao F, Xue L
OncoTargets and Therapy 2021, 14:2773-2787
Published Date: 20 April 2021
A Concise Review: The Role of Stem Cells in Cancer Progression and Therapy
Hayat H, Hayat H, Dwan BF, Gudi M, Bishop JO, Wang P
OncoTargets and Therapy 2021, 14:2761-2772
Published Date: 20 April 2021
lncRNA GSEC Promotes the Progression of Triple Negative Breast Cancer (TNBC) by Targeting the miR-202-5p/AXL Axis
Zhang J, Du C, Zhang L, Wang Y, Zhang Y, Li J
OncoTargets and Therapy 2021, 14:2747-2759
Published Date: 20 April 2021
A Remarkable and Durable Response to Sintilimab and Anlotinib in the First-Line Treatment of an Anaplastic Thyroid Carcinoma without Targetable Genomic Alterations: A Case Report
Gui L, Liu S, Zhang Y, Shi Y
OncoTargets and Therapy 2021, 14:2741-2746
Published Date: 20 April 2021
Exosomes Derived from Pancreatic Cancer Cells Induce Osteoclast Differentiation Through the miR125a-5p/TNFRSF1B Pathway
Zhou Y, Zhu Y, Dong X, Cao G, Li Y, Fan Y, Chen Q, Cai H, Wu Y
OncoTargets and Therapy 2021, 14:2727-2739
Published Date: 19 April 2021
LINC00184 Promotes Ovarian Cancer Cells Proliferation and Cisplatin Resistance by Elevating CNTN1 Expression via Sponging miR-1305
Han Y, You J, Han Y, Liu Y, Huang M, Lu X, Chen J, Zheng Y
OncoTargets and Therapy 2021, 14:2711-2726
Published Date: 19 April 2021
Long Noncoding RNA ZEB1-AS1 Downregulates miR-23a, Promotes Tumor Progression, and Predicts the Survival of Oral Squamous Cell Carcinoma Patients
Wang X, Guo Y, Wang C, Wang Q, Yan G
OncoTargets and Therapy 2021, 14:2699-2710
Published Date: 16 April 2021
Expression and Prognosis of Sperm-Associated Antigen 1 in Human Breast Cancer
Lin S, Lv Y, Zheng L, Mao G, Peng F
OncoTargets and Therapy 2021, 14:2689-2698
Published Date: 16 April 2021
3D Culture of Circulating Tumor Cells for Evaluating Early Recurrence and Metastasis in Patients with Hepatocellular Carcinoma
Hu CL, Zhang YJ, Zhang XF, Fei X, Zhang H, Li CG, Sun B
OncoTargets and Therapy 2021, 14:2673-2688
Published Date: 16 April 2021
GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2+ Macrophage Infiltration in Mice
Li M, Huang T, Li X, Shi Z, Sheng Y, Hu M, Song K
OncoTargets and Therapy 2021, 14:2661-2672
Published Date: 15 April 2021
Desmoplastic Melanoma: A Clinicopathological Analysis of Three Cases in the Chinese Population
Fan Y, Xu M, Liang Y, Wu N, Wang F, Du Q, Bai Y, Liu Y
OncoTargets and Therapy 2021, 14:2651-2660
Published Date: 15 April 2021
Bioinformatics Analysis of the SIRT Family Members and Assessment of Their Potential Clinical Value
Liu M, Yu J, Jin H, Wang S, Ding J, Xing H, He S, Zeng Y
OncoTargets and Therapy 2021, 14:2635-2649
Published Date: 15 April 2021
A Combination of RNA-Seq Analysis and Use of TCGA Database for Determining the Molecular Mechanism and Identifying Potential Drugs for GJB1 in Ovarian Cancer
Yang J, Fan Y, Xie B, Yang D
OncoTargets and Therapy 2021, 14:2623-2633
Published Date: 14 April 2021
Role of G Protein-Coupled Estrogen Receptor in Digestive System Carcinomas: A Minireview
Qiu YA, Xiong J, Yu T
OncoTargets and Therapy 2021, 14:2611-2622
Published Date: 14 April 2021
Construction of the Prediction Model for Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiotherapy Based on Pretreatment Tumor-Infiltrating Macrophage-Associated Biomarkers
Liu X, Zheng S, Peng Y, Zhuang J, Yang Y, Xu Y, Guan G
OncoTargets and Therapy 2021, 14:2599-2610
Published Date: 13 April 2021
A Novel Transcription Factor-Based Prognostic Signature in Endometrial Cancer: Establishment and Validation
Yang X, Cheng Y, Li X, Zhou J, Dong Y, Shen B, Zhao L, Wang J
OncoTargets and Therapy 2021, 14:2579-2598
Published Date: 13 April 2021
Coexistence of Lung Squamous Cell Carcinoma and Pulmonary Tuberculosis Within a Single Lesion: A Case Report
Yu MJ, Li PJ, Liang ZA
OncoTargets and Therapy 2021, 14:2575-2578
Published Date: 13 April 2021
Dihydroartemisinin as a Sensitizing Agent in Cancer Therapies
Li Q, Ma Q, Cheng J, Zhou X, Pu W, Zhong X, Guo X
OncoTargets and Therapy 2021, 14:2563-2573
Published Date: 13 April 2021
Complete Pathologic Response After Concurrent Treatment with Pembrolizumab and Radiotherapy in Metastatic Colorectal Cancer: A Case Report
Yang J, Bi F, Gou H
OncoTargets and Therapy 2021, 14:2555-2561
Published Date: 13 April 2021
MicroRNA-302s Might Regulate ARL4C-Mediated Gastric Cancer Progression via p53 Signaling: Bioinformatics Analysis and Experiments Validation
Xie N, Pan Y, Wu J, Bai Y, Xiao C, Gao X, Wang J, Liu N
OncoTargets and Therapy 2021, 14:2541-2553
Published Date: 13 April 2021
Consequences of Mutations and Abnormal Expression of SMAD4 in Tumors and T Cells
Wan R, Feng J, Tang L
OncoTargets and Therapy 2021, 14:2531-2540
Published Date: 13 April 2021
GDC-0326 Enhances the Effects of 5-Fu in Colorectal Cancer Cells by Inducing Necroptotic Death
Zhang Z, Ju F, Chen F, Wu H, Chen J, Zhong J, Shao L, Zheng S, Wang L, Xue M
OncoTargets and Therapy 2021, 14:2519-2530
Published Date: 13 April 2021
Calycosin Induces Gastric Cancer Cell Apoptosis via the ROS-Mediated MAPK/STAT3/NF-κB Pathway
Zhang Y, Zhang JQ, Zhang T, Xue H, Zuo WB, Li YN, Zhao Y, Sun G, Fu ZR, Zhang Q, Zhao X, Teng Y, Wang AQ, Li JZ, Wang Y, Jin CH
OncoTargets and Therapy 2021, 14:2505-2517
Published Date: 12 April 2021
Hodgkin Lymphoma as a Secondary Neoplasm During Therapy for Chronic Myeloid Leukaemia: Case Report and Review of the Literature
Paczkowska E, Janowski M, Karpińska K, Ryłów M, Zdziarska B, Poncyljusz W, Machaliński B
OncoTargets and Therapy 2021, 14:2497-2503
Published Date: 12 April 2021
Promising Response to Lenalidomide-Combination Therapy in a Discordant Lymphoma Consisting of EBV-Positive Diffuse Large B-Cell Lymphoma and Angioimmunoblastic T-Cell Lymphoma: A Case Report
Hu P, Ben Y, Liu J, Zheng W, Yan X, Zhang Y, Shi W
OncoTargets and Therapy 2021, 14:2489-2495
Published Date: 12 April 2021
Circ_0006168 Promotes the Migration, Invasion and Proliferation of Esophageal Squamous Cell Carcinoma Cells via miR-516b-5p-Dependent Regulation of XBP1
Huang Y, Jiang L, Wei G
OncoTargets and Therapy 2021, 14:2475-2488
Published Date: 12 April 2021
Actin-Like Protein 8 Promotes the Progression of Triple-Negative Breast Cancer via Activating PI3K/AKT/mTOR Pathway
Fan S, Yan S, Yang Y, Shang J, Hao M
OncoTargets and Therapy 2021, 14:2463-2473
Published Date: 12 April 2021
Lipid–Polymer Hybrid Nanoparticle-Based Combination Treatment with Cisplatin and EGFR/HER2 Receptor-Targeting Afatinib to Enhance the Treatment of Nasopharyngeal Carcinoma
Fu D, Li C, Huang Y
OncoTargets and Therapy 2021, 14:2449-2461
Published Date: 9 April 2021
Integrated Profiling Identifies CCNA2 as a Potential Biomarker of Immunotherapy in Breast Cancer
Wang Y, Zhong Q, Li Z, Lin Z, Chen H, Wang P
OncoTargets and Therapy 2021, 14:2433-2448
Published Date: 9 April 2021
Development and Analytical Validation of a Targeted Next-Generation Sequencing Panel to Detect Actionable Mutations for Targeted Therapy
Wang D, Ma K, Deng W, Li J, Xiang S, Zhang Y, Fu Y, Dai H, Huang B
OncoTargets and Therapy 2021, 14:2423-2431
Published Date: 7 April 2021
Rapid Disease Progression in a Patient with Advanced NSCLC Harboring a Germline MET Exon 14 Skipping Mutation: A Case Report
Jiao Y, Fang C, Yang Y, Shao L, Huang Y, Sun Q, Dong Y
OncoTargets and Therapy 2021, 14:2417-2421
Published Date: 7 April 2021
Advances in Understanding the LncRNA-Mediated Regulation of the Hippo Pathway in Cancer
Wang M, Xu T, Feng W, Liu J, Wang Z
OncoTargets and Therapy 2021, 14:2397-2415
Published Date: 7 April 2021
Tip of the Iceberg: Roles of CircRNAs in Cancer Glycolysis
Li T, Xian H, Dai L, Tang Y, Liang X
OncoTargets and Therapy 2021, 14:2379-2395
Published Date: 7 April 2021
Construction of miRNA-mRNA Regulatory Network and Prognostic Signature in Endometrial Cancer
Sun R, Liu J, Nie S, Li S, Yang J, Jiang Y, Cheng W
OncoTargets and Therapy 2021, 14:2363-2378
Published Date: 6 April 2021
Evaluation of the UK Myeloma Research Alliance Risk Profile in Chinese Patients with Newly Diagnosed Multiple Myeloma without Autologous Stem Cell Transplantation
Ma K, Ye J, Wang L, Sun C, Zhou X
OncoTargets and Therapy 2021, 14:2349-2361
Published Date: 6 April 2021
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and Therapy 2021, 14:2339-2348
Published Date: 6 April 2021
LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling [Corrigendum]
Wang Q, Liao J, He Z, Su Y, Lin D, Xu L, Xu H, Lin J
OncoTargets and Therapy 2021, 14:2337-2338
Published Date: 6 April 2021
Serum Exosomal miRNA Might Be a Novel Liquid Biopsy to Identify Leptomeningeal Metastasis in Non-Small Cell Lung Cancer
Xu Q, Ye L, Huang L, Zhou L, Chen X, Ye M, Wu G, Zhan P, Lv T, Song Y
OncoTargets and Therapy 2021, 14:2327-2335
Published Date: 1 April 2021
miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6
Tang J, Gao W, Liu G, Sheng W, Zhou J, Dong Q, Dong M
OncoTargets and Therapy 2021, 14:2311-2325
Published Date: 31 March 2021
PD-L1 Expression and Outcome in Patients with Metastatic Non-Small Cell Lung Cancer and EGFR Mutations Receiving EGFR-TKI as Frontline Treatment
Chang CY, Lai YC, Wei YF, Chen CY, Chang SC
OncoTargets and Therapy 2021, 14:2301-2309
Published Date: 31 March 2021
LncRNA LHFPL3-AS1 Promotes Oral Squamous Cell Carcinoma Growth and Cisplatin Resistance Through Targeting miR-362-5p/CHSY1 Pathway
Li J, Xu X, Zhang D, Lv H, Lei X
OncoTargets and Therapy 2021, 14:2293-2300
Published Date: 31 March 2021
LINC00460 Promotes Cell Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Head and Neck Squamous Cell Carcinoma via miR-320a/BGN Axis
Yang Y, Wang R, Feng L, Ma H, Fang J
OncoTargets and Therapy 2021, 14:2279-2291
Published Date: 30 March 2021
Identification of Metabolic-Associated Genes for the Prediction of Colon and Rectal Adenocarcinoma
Cui Y, Han B, Zhang H, Liu H, Zhang F, Niu R
OncoTargets and Therapy 2021, 14:2259-2277
Published Date: 31 March 2021
Remodels the Immunosuppressive Tumor Microenvironment by Combination of Bacillus Calmette–Guérin and Anti-PD-L1 in an Orthotopic Triple-Negative Breast Cancer Mouse Model
Lu Y, Huang X, Liu X, He Y, Hu Z, Xu JW, Cao G, He W
OncoTargets and Therapy 2021, 14:2247-2258
Published Date: 30 March 2021
Bronchiolar Adenoma Transforming to Invasive Mucinous Adenocarcinoma: A Case Report
Han X, Hao J, Ding S, Wang EH, Wang L
OncoTargets and Therapy 2021, 14:2241-2246
Published Date: 30 March 2021
Long Noncoding RNA LINC00460 Facilitates Colorectal Cancer Progression by Negatively Regulating miR-613 [Corrigendum]
Wang L, Chen X, Sun X, Suo J
OncoTargets and Therapy 2021, 14:2239-2240
Published Date: 30 March 2021
MicroRNA-769-5p Promotes the Growth of Glioma Cells by Targeting Lysine Methyltransferase 2A [Corrigendum]
Chang M, Yan P, Zhang B, Zhang G, Wang J, Ge H, Han N, Du C, Shi W, Tian Y
OncoTargets and Therapy 2021, 14:2237-2238
Published Date: 29 March 2021
LncRNA ANRIL Regulates Ovarian Cancer Progression and Tumor Stem Cell-Like Characteristics via miR-324-5p/Ran Axis [Retraction]
Wang K, Hu YB, Zhao Y, Ye C
OncoTargets and Therapy 2021, 14:2235-2236
Published Date: 30 March 2021
Case Report: SMARCB1 (INI-1)-Deficient Carcinoma of the Nasal Cavity with Pure Yolk Sac Tumor Differentiation and Elevated Serum AFP Levels
Li CY, Han Y, Xu K, Wu S, Lin XY, Cao H
OncoTargets and Therapy 2021, 14:2227-2233
Published Date: 29 March 2021
Long Non-Coding RNA LINC00313 Accelerates Cervical Carcinoma Progression by miR-4677-3p/CDK6 Axis
Zhai Y, Liu Y, Wang Z, Wang W, Zhou J, Lu J
OncoTargets and Therapy 2021, 14:2213-2226
Published Date: 29 March 2021
Analysis of the Clinicopathological Characteristics of Stage I–III Colorectal Cancer Patients Deficient in Mismatch Repair Proteins
Liang Y, Cai X, Zheng X, Yin H
OncoTargets and Therapy 2021, 14:2203-2212
Published Date: 26 March 2021
A Review of Chimeric Antigen Receptor T-Cell Therapy for Myeloma and Lymphoma
Atrash S, Moyo TK
OncoTargets and Therapy 2021, 14:2185-2201
Published Date: 26 March 2021
Dramatic Responses of Recurrent Upper Urinary Tract Urothelial Carcinoma Harboring FGFR3 and TP53 Activating Mutations to Pembrolizumab in Combination with Erdafitinib: A Case Report
Ding X, Zong J, Li X, Bai X, Tan B, Sun W, Wang R, Ding Y
OncoTargets and Therapy 2021, 14:2177-2183
Published Date: 25 March 2021
Upregulated MicroRNA-483-3p is an Early Event in Pancreatic Ductal Adenocarcinoma (PDAC) and as a Powerful Liquid Biopsy Biomarker in PDAC
Shao H, Zhang Y, Yan J, Ban X, Fan X, Chang X, Lu Z, Wu Y, Zong L, Mo S, Yu S, Chen J
OncoTargets and Therapy 2021, 14:2163-2175
Published Date: 25 March 2021
CD8+CD39+ T Cells Mediate Anti-Tumor Cytotoxicity in Bladder Cancer
Zhu W, Zhao Z, Feng B, Yu W, Li J, Guo H, Yang R
OncoTargets and Therapy 2021, 14:2149-2161
Published Date: 25 March 2021
Primary Tumor Radiotherapy During EGFR-TKI Disease Control Improves Survival of Treatment Naïve Advanced EGFR-Mutant Lung Adenocarcinoma Patients
Hsu KH, Huang JW, Tseng JS, Chen KW, Weng YC, Yu SL, Yang TY, Huang YH, Chen JJW, Chen KC, Chang GC
OncoTargets and Therapy 2021, 14:2139-2148
Published Date: 25 March 2021
Identification of Novel Alectinib-Resistant ALK Mutation G1202K with Sensitization to Lorlatinib: A Case Report and in silico Structural Modelling
Yang P, Cao R, Bao H, Wu X, Yang L, Zhu D, Zhang L, Peng L, Cai Y, Zhang W, Shao Y
OncoTargets and Therapy 2021, 14:2131-2138
Published Date: 25 March 2021
Recent Advances in Our Knowledge of mCRC Tumor Biology and Genetics: A Focus on Targeted Therapy Development
Gmeiner WH
OncoTargets and Therapy 2021, 14:2121-2130
Published Date: 25 March 2021
Oral PI3K-δ,γ Inhibitor for the Management of People with Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: A Narrative Review on Duvelisib
Shah A, Barrientos JC
OncoTargets and Therapy 2021, 14:2109-2119
Published Date: 25 March 2021
A Rare Case of Primary Signet-Ring Cell Cervical Carcinoma: Early Stage with Independent Bilateral Ovarian Metastases
Li S, Gan F, Luo M, Luo P
OncoTargets and Therapy 2021, 14:2101-2107
Published Date: 23 March 2021
Global Characterization of Immune Infiltration in Clear Cell Renal Cell Carcinoma
Zheng Y, Wen Y, Cao H, Gu Y, Yan L, Wang Y, Wang L, Zhang L, Shao F
OncoTargets and Therapy 2021, 14:2085-2100
Published Date: 22 March 2021
Evaluation of Cervical High-Grade Squamous Intraepithelial Lesions-Correlated Markers as Triage Strategy for Colposcopy After Co-Testing
Huo X, Sun H, Cao D, Yang J, Peng P, Kong L, Chen F, Shen K, Li S
OncoTargets and Therapy 2021, 14:2075-2084
Published Date: 19 March 2021
Helicobacter pylori Regulates the Apoptosis of Human Megakaryocyte Cells via NF-κB/IL-17 Signaling
Lei H, Ma Y, Tan J, Liu Q
OncoTargets and Therapy 2021, 14:2065-2074
Published Date: 19 March 2021
The Association Between Inflammation and Immunosuppression: Implications for ICI Biomarker Development
Sacdalan DB, Lucero JA
OncoTargets and Therapy 2021, 14:2053-2064
Published Date: 18 March 2021
Role and Therapeutic Potential of Melatonin in Various Type of Cancers
Gurunathan S, Qasim M, Kang MH, Kim JH
OncoTargets and Therapy 2021, 14:2019-2052
Published Date: 18 March 2021
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer
Deng Z, Xiao M, Du D, Luo N, Liu D, Liu T, Lian D, Peng J
OncoTargets and Therapy 2021, 14:2003-2017
Published Date: 18 March 2021
A Case of Solid Variant of Adenoid Cystic Carcinoma from Trachea: A Case Report and Review of Literature
Gao F, Zang L, He J, Xu W
OncoTargets and Therapy 2021, 14:1997-2002
Published Date: 18 March 2021
Apatinib Combined with Irinotecan in the Treatment of Advanced Small-Cell Esophageal Carcinoma: A Case Report
Guo L, Zou X, Gu Y, Yi L, Zhao J, Wu G
OncoTargets and Therapy 2021, 14:1989-1995
Published Date: 18 March 2021
Organ-Specific Tumor Response to Pembrolizumab in Advanced Urothelial Carcinoma After Platinum-Based Chemotherapy
Furubayashi N, Negishi T, Sakamoto N, Shimokawa H, Morokuma F, Song Y, Hori Y, Tomoda T, Tokuda N, Seki N, Kuroiwa K, Nakamura M
OncoTargets and Therapy 2021, 14:1981-1988
Published Date: 18 March 2021
Potential Role of Musashi-2 RNA-Binding Protein in Cancer EMT
Sun J, Sheng W, Ma Y, Dong M
OncoTargets and Therapy 2021, 14:1969-1980
Published Date: 17 March 2021
Anti–PD-1 Monotherapy for Advanced NSCLC Patients with Older Age or Those with Poor Performance Status
Matsubara T, Seto T, Takamori S, Fujishita T, Toyozawa R, Ito K, Yamaguchi M, Okamoto T
OncoTargets and Therapy 2021, 14:1961-1968
Published Date: 17 March 2021
Lack of Synergy Between β-Agonist Treatment and a Blockage of Sarcoplasmic Calcium Flow in a Rat Cancer Cachexia Model
Busquets S, Castillejo M, Jové Q, Jude B, Mejías P, López-Soriano FJ, Argilés JM
OncoTargets and Therapy 2021, 14:1953-1959
Published Date: 17 March 2021
Assessment of the Circulating Tumor Cells and Microsatellite Instability in Colorectal Cancer Patients: Prognostic and Diagnostic Value
Alsayed A, Salem SE, El Serafi MM, Abdellateif MS, Zekri ARN, Mohanad M, Bahnassy AA
OncoTargets and Therapy 2021, 14:1937-1951
Published Date: 16 March 2021
Anti-Lung Cancer Targets of Radix Paeoniae Rubra and Biological Molecular Mechanism: Network Pharmacological Analyses and Experimental Validation
Ma Y, Li G, Yu M, Cao K, Li Q, Sun X, Yang G, Wang X
OncoTargets and Therapy 2021, 14:1925-1936
Published Date: 16 March 2021
Propofol Suppresses Proliferation, Migration, Invasion and Promotes Apoptosis by Upregulating microRNA-140-5p in Gastric Cancer Cells [Retraction]
Zhu F, Li Q, Yang Y, Wang L, Wang J
OncoTargets and Therapy 2021, 14:1923-1924
Published Date: 16 March 2021
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis
Jin Y, Kang Y, Peng X, Yang L, Li Q, Mei Q, Chen X, Hu G, Tang Y, Yuan X
OncoTargets and Therapy 2021, 14:1911-1922
Published Date: 16 March 2021
Single-Cell Sequencing, an Advanced Technology in Lung Cancer Research
Wang H, Meng D, Guo H, Sun C, Chen P, Jiang M, Xu Y, Yu J, Fang Q, Zhu J, Zhao W, Wu S, Zhao S, Li W, Chen B, Wang L, He Y
OncoTargets and Therapy 2021, 14:1895-1909
Published Date: 16 March 2021
LncRNA HOTAIR Promotes Cancer Stem-Like Cells Properties by Sponging miR-34a to Activate the JAK2/STAT3 Pathway in Pancreatic Ductal Adenocarcinoma
Deng S, Wang J, Zhang L, Li J, Jin Y
OncoTargets and Therapy 2021, 14:1883-1893
Published Date: 12 March 2021
Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer
Seesaha PK, Wang KX, Wang GQ, Cui TY, Zhao FJ, Pan LL, Li XC, Shu YQ, Chen XF
OncoTargets and Therapy 2021, 14:1873-1882
Published Date: 12 March 2021
LncRNA ILF3-AS1 Promotes the Progression of Colon Adenocarcinoma Cells Through the miR-619-5p/CAMK1D Axis
Liu W, Li S
OncoTargets and Therapy 2021, 14:1861-1872
Published Date: 12 March 2021
MiR-126 Regulates Proliferation and Invasion in the Bladder Cancer BLS Cell Line by Targeting the PIK3R2-Mediated PI3K/Akt Signaling Pathway [Retraction]
Xiao J, Lin H, Zhu Y, Zhu Y, Chen L
OncoTargets and Therapy 2021, 14:1859-1860
Published Date: 10 March 2021
C-Terminal of E1A Binding Protein 1 Enhances the Migration of Gastric Epithelial Cells and Has a Clinicopathologic Significance in Human Gastric Carcinoma [Retraction]
Wang C, Wang M, Xing B, Chi Z, Wang H, Lie C, Dong H
OncoTargets and Therapy 2021, 14:1857-1858
Published Date: 10 March 2021
ARID4B Knockdown Suppresses PI3K/AKT Signaling and Induces Apoptosis in Human Glioma Cells
Luo SM, Tsai WC, Tsai CK, Chen Y, Hueng DY
OncoTargets and Therapy 2021, 14:1843-1855
Published Date: 10 March 2021
Natural Polyphyllins (I, II, D, VI, VII) Reverses Cancer Through Apoptosis, Autophagy, Mitophagy, Inflammation, and Necroptosis
Ahmad B, Gamallat Y, Khan MF, Din SR, Israr M, Ahmad M, Tahir N, Azam N, Rahman KU, Xin W, Zexu W, Linjie P, Su P, Liang W
OncoTargets and Therapy 2021, 14:1821-1841
Published Date: 10 March 2021
Circ-PITX1 Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1248/CCND2 Axis
Yue Q, Xu Y, Deng X, Wang S, Qiu J, Qian B, Zhang Y
OncoTargets and Therapy 2021, 14:1807-1819
Published Date: 9 March 2021
Current and Emerging Therapeutic Options for Hairy Cell Leukemia Variant
Liu Q, Harris N, Epperla N, Andritsos LA
OncoTargets and Therapy 2021, 14:1797-1805
Published Date: 9 March 2021
Complete Response to Pembrolizumab in Advanced Colon Cancer Harboring Somatic POLE F367S Mutation with Microsatellite Stability Status: A Case Study
Chen J, Lou H
OncoTargets and Therapy 2021, 14:1791-1796
Published Date: 9 March 2021
A Retrospective Case Study of 13 Uterine Perivascular Epithelioid Cell Neoplasm (PEComa) Patients
Gu J, Wang W, Wang S
OncoTargets and Therapy 2021, 14:1783-1790
Published Date: 9 March 2021
P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization
Wang Q, Zhang J, Fang S, Wang J, Han X, Liu F, Jin G
OncoTargets and Therapy 2021, 14:1771-1782
Published Date: 8 March 2021
High Expression of LINC01268 is Positively Associated with Hepatocellular Carcinoma Progression via Regulating MAP3K7
Jin X, Fu WX, Li D, Wang N, Chen J, Zeng Z, Guo J, Liu H, Zhong X, Peng H, Yu X, Sun J, Zhang X, Wang X, Xu B, Lin Y, Liu J, Kutter C, Li Y
OncoTargets and Therapy 2021, 14:1753-1769
Published Date: 8 March 2021
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma
Huang H, Tan M, Zheng L, Yan G, Li K, Lu D, Cui X, He S, Lei D, Zhu B, Zhao J
OncoTargets and Therapy 2021, 14:1737-1751
Published Date: 5 March 2021
Biological Function of HYOU1 in Tumors and Other Diseases
Rao S, Oyang L, Liang J, Yi P, Han Y, Luo X, Xia L, Lin J, Tan S, Hu J, Wang H, Tang L, Pan Q, Tang Y, Zhou Y, Liao Q
OncoTargets and Therapy 2021, 14:1727-1735
Published Date: 5 March 2021
Early Study of Tumor Abnormal Protein in Gastric Adenocarcinoma
Zhang M, Wang X, Wang Z
OncoTargets and Therapy 2021, 14:1719-1726
Published Date: 5 March 2021
Carbonic Anhydrase XII is a Clinically Significant, Molecular Tumor-Subtype Specific Therapeutic Target in Glioma with the Potential to Combat Invasion of Brain Tumor Cells
Li G, Chen TW, Nickel AC, Muhammad S, Steiger HJ, Tzaridis T, Hänggi D, Zeidler R, Zhang W, Kahlert UD
OncoTargets and Therapy 2021, 14:1707-1718
Published Date: 4 March 2021
Prognostic Value and Biological Functions of RNA Binding Proteins in Stomach Adenocarcinoma
Li J, Zhou W, Wei J, Xiao X, An T, Wu W, He Y
OncoTargets and Therapy 2021, 14:1689-1705
Published Date: 4 March 2021
Targeting the IDO-BCL2A1-Cytochrome c Pathway Promotes Apoptosis in Oral Squamous Cell Carcinoma
Zheng Q, Gan G, Gao X, Luo Q, Chen F
OncoTargets and Therapy 2021, 14:1673-1687
Published Date: 4 March 2021
LncRNA KCNQ1OT1 Promotes Proliferation, Invasion and Metastasis of Prostate Cancer by Regulating miR-211-5p/CHI3L1 Pathway
Hao H, Chen H, Xie L, Liu H, Wang D
OncoTargets and Therapy 2021, 14:1659-1671
Published Date: 3 March 2021
RPN2 Predicts Poor Prognosis and Promotes Bladder Cancer Growth and Metastasis via the PI3K-Akt Pathway
Han C, Chen S, Ma H, Wen X, Wang Z, Xu Y, Jin X, Yu X, Wang M
OncoTargets and Therapy 2021, 14:1643-1657
Published Date: 3 March 2021
High VCAM-1 Predicts Poor Prognosis and is Associated with Chemotherapy Resistance in Nasopharyngeal Carcinoma
Huang Y, Miao H, Xia C, Feng H, Xu S, Liang Z, Wang Y, Zhao C, Qin G, Ou X, Zhao F
OncoTargets and Therapy 2021, 14:1633-1641
Published Date: 2 March 2021
Estimating Survival in Patients with Non-Small-Cell Lung Cancer and Brain Metastases: A Verification of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA)
Li J, Jing W, Zhai X, Jia W, Zhu H, Yu J
OncoTargets and Therapy 2021, 14:1623-1631
Published Date: 2 March 2021
Antiangiogenesis Combined with Immunotherapy to Treat Advanced Small-Cell Carcinoma of the Esophagus Resistant to Chemotherapy: According to the Guidance of Next-Generation Sequencing
Jiang M, Zhang X
OncoTargets and Therapy 2021, 14:1613-1621
Published Date: 2 March 2021
REG4 is a Potential Biomarker for Radiochemotherapy Sensitivity in Colorectal Cancer
Gao L, Wu X, Zhang L, Dai Y, Zhu Z, Zhi Y, Wang K
OncoTargets and Therapy 2021, 14:1605-1611
Published Date: 2 March 2021
An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma
Chen K, Zhu P, Liao Y, Yan L, Feng R, Zhai W
OncoTargets and Therapy 2021, 14:1589-1604
Published Date: 2 March 2021
Partial Response to Pyrotinib Plus Capecitabine in an Advanced Breast Cancer Patient with HER2 Amplification and R157W Mutation After Anti-HER2 Treatment: A Case Report and Literature Review
Qu Y, Liu Y, Ding K, Li Y, Hong X, Zhang H
OncoTargets and Therapy 2021, 14:1581-1588
Published Date: 2 March 2021
Clinical Significance and Oncogenic Activity of GRWD1 Overexpression in the Development of Colon Carcinoma
Zhou X, Shang J, Liu X, Zhuang JF, Yang YF, Zhang YY, Guan GX
OncoTargets and Therapy 2021, 14:1565-1580
Published Date: 2 March 2021
MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway
Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K
OncoTargets and Therapy 2021, 14:1553-1564
Published Date: 2 March 2021
Circulating Tumor Cells Undergoing the Epithelial–Mesenchymal Transition: Influence on Prognosis in Cytokeratin 19-Positive Hepatocellular Carcinoma
Zhang Q, Xing W, Zhang J, Hu J, Qi L, Xiang B
OncoTargets and Therapy 2021, 14:1543-1552
Published Date: 2 March 2021
Biological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase
Qiu Z, Deng W, Hong Y, Zhao L, Li M, Guan Y, Su Y, Chen C, Shi Q, Yu J, Wang W
OncoTargets and Therapy 2021, 14:1531-1542
Published Date: 1 March 2021
The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma
Peng X, Sun J, Long Y, Xiao D, Zhou J, Tao Y, Liu S
OncoTargets and Therapy 2021, 14:1517-1529
Published Date: 1 March 2021
Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application
Pu F, Chen F, Liu J, Zhang Z, Shao Z
OncoTargets and Therapy 2021, 14:1501-1516
Published Date: 1 March 2021
FAST1 Predicts Poor Survival of Renal Carcinoma and Promotes Its Progression Through the TGF-β/Smad Pathway
Tian T, Fu X, Hu L, Yang X, Sun P, Sun F
OncoTargets and Therapy 2021, 14:1487-1499
Published Date: 26 February 2021
FLT3-ITD Mutation and FLT3 Ligand Plasma Level Were Not Associated with One-Year Survival of Indonesian Acute Myeloid Leukemia Patients
Rinaldi I, Louisa M, Mulya Sari R, Arwanih E
OncoTargets and Therapy 2021, 14:1479-1486
Published Date: 26 February 2021
A Functional Food Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Inflammatory Colorectal Cancer in Mice
Zhang J, Chen Z, Lu Y, Tu D, Zou F, Lin S, Yu W, Miao M, Shi H
OncoTargets and Therapy 2021, 14:1465-1477
Published Date: 26 February 2021
Small Proline-Rich Protein 2B Facilitates Gastric Adenocarcinoma Proliferation via MDM2-p53/p21 Signaling Pathway
Yao L, Yan J, Cheng F, Gan L, Huang Y, Zheng L, Fang N
OncoTargets and Therapy 2021, 14:1453-1463
Published Date: 26 February 2021
Serum Exosomal miRNA-1226 as Potential Biomarker of Pancreatic Ductal Adenocarcinoma
Wang C, Wang J, Cui W, Liu Y, Zhou H, Wang Y, Chen X, Chen X, Wang Z
OncoTargets and Therapy 2021, 14:1441-1451
Published Date: 26 February 2021
TRIM11 Promotes Proliferation, Migration, Invasion and EMT of Gastric Cancer by Activating β-Catenin Signaling
Lan Q, Tan X, He P, Li W, Tian S, Dong W
OncoTargets and Therapy 2021, 14:1429-1440
Published Date: 25 February 2021
Research Trends and Regulation of CCL5 in Prostate Cancer
Huang R, Guo L, Gao M, Li J, Xiang S
OncoTargets and Therapy 2021, 14:1417-1427
Published Date: 25 February 2021
Renal Transcriptomics Reveals the Carcinogenic Mechanism of Ethyl Carbamate in Musalais
Wang W, Han ZJ, Guo D, Xiang Y
OncoTargets and Therapy 2021, 14:1401-1416
Published Date: 25 February 2021
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis
Li L, Wang Z, Lu T, Li Y, Pan M, Yu D, Hu G
OncoTargets and Therapy 2021, 14:1387-1399
Published Date: 25 February 2021
Expression and Prognostic Value of Tumor-Infiltrating Lymphocytes and PD-L1 in Hepatocellular Carcinoma
Nie H, He T, Wang L, Zhang L
OncoTargets and Therapy 2021, 14:1377-1385
Published Date: 25 February 2021
Secondary Nasopharyngeal Mixed Adenoneuroendocrine Carcinoma After Radical Radiotherapy for Nasopharyngeal Carcinoma: A Rare Case and Literature Review
Huang D, Huang C, Wang H, He L, Zhang J, Zhong X, Guo Z, Yuan Y, Zhang W
OncoTargets and Therapy 2021, 14:1367-1376
Published Date: 25 February 2021
Promising Molecular Targets for the Targeted Therapy of Biliary Tract Cancers: An Overview
Yang W, Sun Y
OncoTargets and Therapy 2021, 14:1341-1366
Published Date: 25 February 2021
Downregulation of LncRNA DARS-AS1 Inhibits the Tumorigenesis of Cervical Cancer via Inhibition of IGF2BP3
Zhu J, Han S
OncoTargets and Therapy 2021, 14:1331-1340
Published Date: 25 February 2021
Near-Infrared Light-Triggered Thermosensitive Liposomes Modified with Membrane Peptides for the Local Chemo/Photothermal Therapy of Melanoma
Li X, Yang C, Tao Y, Hou X, Liu Y, Sang H, Jiang G
OncoTargets and Therapy 2021, 14:1317-1329
Published Date: 25 February 2021
Increased HSF1 Promotes Infiltration and Metastasis in Cervical Cancer via Enhancing MTDH-VEGF-C Expression
Shi X, Deng Z, Wang S, Zhao S, Xiao L, Zou J, Li T, Tan S, Tan S, Xiao X
OncoTargets and Therapy 2021, 14:1305-1315
Published Date: 26 February 2021
Anti-Proliferative, Pro-Apoptotic, Anti-Migrative and Tumor-Inhibitory Effects and Pleiotropic Mechanism of Theaflavin on B16F10 Melanoma Cells
Zhang L, Meng S, Yan B, Chen J, Zhou L, Shan L, Wang Y
OncoTargets and Therapy 2021, 14:1291-1304
Published Date: 25 February 2021
Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC)
Huang G, Wu Q, Zheng Z, Shao T, Li F, Lu X, Ye H, Chen G, Song Y, Zeng W, Ai Y, Lv X
OncoTargets and Therapy 2021, 14:1275-1289
Published Date: 25 February 2021
Ouabain Exhibited Strong Anticancer Effects in Melanoma Cells via Induction of Apoptosis, G2/M Phase Arrest, and Migration Inhibition
Wang L, Cai W, Han B, Zhang J, Yu B, Chen M
OncoTargets and Therapy 2021, 14:1261-1273
Published Date: 25 February 2021
MicroRNA-1249 Targets G Protein Subunit Alpha 11 and Facilitates Gastric Cancer Cell Proliferation, Motility and Represses Cell Apoptosis
Zhang H, Fu T, Zhang C
OncoTargets and Therapy 2021, 14:1249-1259
Published Date: 24 February 2021
Actinidia eriantha Polysaccharide and PD1-Antibody Combination Therapy Enhances Antitumor Efficacy in Colorectal Cancer–Xenograft Mice
Li J, Wang Y, Jin W, Shen L
OncoTargets and Therapy 2021, 14:1239-1248
Published Date: 24 February 2021
TRPM2-AS Promotes Bladder Cancer by Targeting miR-22-3p and Regulating GINS2 mRNA Expression
Tian Y, Guan Y, Su Y, Yang T, Yu H
OncoTargets and Therapy 2021, 14:1219-1237
Published Date: 23 February 2021
Cancer-Associated Fibroblasts Positively Correlate with Dedifferentiation and Aggressiveness of Thyroid Cancer
Wen S, Qu N, Ma B, Wang X, Luo Y, Xu W, Jiang H, Zhang Y, Wang Y, Ji Q
OncoTargets and Therapy 2021, 14:1205-1217
Published Date: 22 February 2021
KDM5C Expedites Lung Cancer Growth and Metastasis Through Epigenetic Regulation of MicroRNA-133a
Zhang Q, Xu L, Wang J, Zhu X, Ma Z, Yang J, Li J, Jia X, Wei L
OncoTargets and Therapy 2021, 14:1187-1204
Published Date: 22 February 2021
Novel lncRNA LINC00941 Promotes Proliferation and Invasion of Colon Cancer Through Activation of MYC
Chang L, Zhou D, Luo S
OncoTargets and Therapy 2021, 14:1173-1186
Published Date: 22 February 2021
miR-744-5p Inhibits Multiple Myeloma Proliferation, Epithelial Mesenchymal Transformation and Glycolysis by Targeting SOX12/Wnt/β-Catenin Signaling
Guo B, Xiao C, Liu Y, Zhang N, Bai H, Yang T, Xiang Y, Nan Y, Li Q, Zhang W, Huang D
OncoTargets and Therapy 2021, 14:1161-1172
Published Date: 22 February 2021
LINC00466 Impacts Cell Proliferation, Metastasis and Sensitivity to Temozolomide of Glioma by Sponging miR-137 to Regulate PPP1R14B Expression
Zhao M, Shao Y, Xu J, Zhang B, Li C, Gong J
OncoTargets and Therapy 2021, 14:1147-1159
Published Date: 19 February 2021
Identification and Functional Validation of Radioresistance-Related Genes AHNAK2 and EVPL in Esophageal Squamous Cell Carcinoma by Exome and Transcriptome Sequencing Analyses
Hou Q, Jiang Z, Li Z, Jiang M
OncoTargets and Therapy 2021, 14:1131-1145
Published Date: 18 February 2021
Circular RNA circDNM3OS Functions as a miR-145-5p Sponge to Accelerate Cholangiocarcinoma Growth and Glutamine Metabolism by Upregulating MORC2
Su Y, Yu T, Wang Y, Huang X, Wei X
OncoTargets and Therapy 2021, 14:1117-1129
Published Date: 17 February 2021
Poor Prognosis of Pulmonary Adenosquamous Carcinoma with NRAS and HRAS Double Mutation
Zhao J, Zhang X, He M, Chen X, Cui X, Qin T, Niu X, Zhao L
OncoTargets and Therapy 2021, 14:1113-1116
Published Date: 17 February 2021
Prognostic Significance of the Combination of Fibrinogen and Tumor Marker Index in Esophageal Squamous Cell Carcinoma Patients
Qiao Y, Ma M, Zhang H, Yu Z, Tang P
OncoTargets and Therapy 2021, 14:1101-1111
Published Date: 17 February 2021
Synchronous Multiple Lung Cancers with Lymph Node Metastasis and Different EGFR Mutations: Intrapulmonary Metastasis or Multiple Primary Lung Cancers?
Qu R, Tu D, Ping W, Zhang N, Fu X
OncoTargets and Therapy 2021, 14:1093-1099
Published Date: 16 February 2021
Icotinib versus Cisplatin Plus Docetaxel as Adjuvant Chemotherapy in Patients with Stage II (N1+) Non-Small Cell Lung Cancer Harboring Positive EGFR Mutations: A Single-Center Retrospective Study
Pan S, Wang S, Li W, Chai Y
OncoTargets and Therapy 2021, 14:1083-1091
Published Date: 16 February 2021
Pulmonary Lymphoepithelioma-Like Carcinoma Treated with Immunotherapy or Chemotherapy: A Single Institute Experience
Fu Y, Zheng Y, Wang PP, Chen YY, Ding ZY
OncoTargets and Therapy 2021, 14:1073-1081
Published Date: 16 February 2021
Transiently Elevated TC and sdLDL-C Levels and Falsely Low LDL-C Levels in Patients with Extrahepatic Cholangiocarcinoma
Guo Y, Zhang YG, Li HC, Xu YH
OncoTargets and Therapy 2021, 14:1061-1071
Published Date: 15 February 2021
AG-1024 Sensitizes Sorafenib-Resistant Hepatocellular Carcinoma Cells to Sorafenib via Enhancing G1/S Arrest
Zhou W, Lou W, Chen J, Ding B, Chen B, Xie H, Zhou L, Zheng S, Jiang D
OncoTargets and Therapy 2021, 14:1049-1059
Published Date: 15 February 2021
Exonuclease 1 (EXO1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Lung Adenocarcinoma
Zhou CS, Feng MT, Chen X, Gao Y, Chen L, Li LD, Li DH, Cao YQ
OncoTargets and Therapy 2021, 14:1033-1048
Published Date: 15 February 2021
Comprehensive Analysis of Gene Expression Changes and Validation in Hepatocellular Carcinoma
Zhang H, Liu R, Sun L, Guo W, Ji X, Hu X
OncoTargets and Therapy 2021, 14:1021-1031
Published Date: 15 February 2021
Tandem Mass Tag-Based Proteomic Analysis of Potential Biomarkers for Hepatocellular Carcinoma Differentiation
Wang W, Li Q, Huang G, Lin BY, Lin D, Ma Y, Zhang Z, Chen T, Zhou J
OncoTargets and Therapy 2021, 14:1007-1020
Published Date: 12 February 2021
GATA1 Gene Silencing Inhibits Invasion, Proliferation and Migration of Cholangiocarcinoma Stem Cells via Disrupting the PI3K/AKT Pathway [Retraction]
Shi G, Zhang H, Yu Q, Hu C, Ji Y
OncoTargets and Therapy 2021, 14:1005-1006
Published Date: 12 February 2021
The Inhibitive Effect of sh-HIF1A-AS2 on the Proliferation, Invasion, and Pathological Damage of Breast Cancer via Targeting miR-548c-3p Through Regulating HIF-1α/VEGF Pathway in vitro and vivo [Retraction]
Guo X, Lee S, Cao P
OncoTargets and Therapy 2021, 14:1003-1004
Published Date: 11 February 2021
MicroRNA-140-5p is Downregulated in Osteosarcoma and Overexpression of MicroRNA-140-5p Inhibits Cancer Cell Proliferation by Downregulating GLUT-1
Geng X, Wang H, Xu L, Han Y, Liu Y
OncoTargets and Therapy 2021, 14:995-1002
Published Date: 11 February 2021
A Case Report: Cutaneous Metastasis of Advanced Rectal Cancer with BRAF Mutation
Zhou S, Tang W, Wang Q, Zhang X, Jin X, Xu X, Fu J
OncoTargets and Therapy 2021, 14:989-993
Published Date: 11 February 2021
Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer
Wang G, Wang X, Han M, Wang X
OncoTargets and Therapy 2021, 14:979-988
Published Date: 11 February 2021
IgG Fc Binding Protein (FCGBP) is Down-Regulated in Metastatic Lesions and Predicts Survival in Metastatic Colorectal Cancer Patients
Yuan Z, Zhao Z, Hu H, Zhu Y, Zhang W, Tang Q, Huang R, Gao F, Zou C, Wang G, Wang X
OncoTargets and Therapy 2021, 14:967-977
Published Date: 11 February 2021
Extragastrointestinal Stromal Tumor Presenting as a Recurrent Vaginal Mass: Case Report
Liu S, Pan P, Han B, Wang J, Sun M, Sun Y
OncoTargets and Therapy 2021, 14:959-965
Published Date: 10 February 2021
Malignant Acanthosis Nigricans with Recurrent Bladder Cancer: A Case Report and Review of Literature
Zhang R, Jiang M, Lei W, Wang A
OncoTargets and Therapy 2021, 14:951-957
Published Date: 10 February 2021
TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT
Huang Z, Yan Y, Tang P, Cai J, Cao X, Wang Z, Zhang F, Shen B
OncoTargets and Therapy 2021, 14:937-949
Published Date: 10 February 2021
Successful Use of Nivolumab in a Patient with Head and Neck Cancer After Allogeneic Bone Marrow Transplantation
Dong X, Lu N, Tong Z, Shi Y
OncoTargets and Therapy 2021, 14:929-936
Published Date: 10 February 2021
Research Progress on Regulating LncRNAs of Hepatocellular Carcinoma Stem Cells
Zhang X, Zhu Y
OncoTargets and Therapy 2021, 14:917-927
Published Date: 10 February 2021
Baicalein Represses Cervical Cancer Cell Growth, Cell Cycle Progression and Promotes Apoptosis via Blocking AKT/mTOR Pathway by the Regulation of circHIAT1/miR-19a-3p Axis
Hu J, Wang R, Liu Y, Zhou J, Shen K, Dai Y
OncoTargets and Therapy 2021, 14:905-916
Published Date: 9 February 2021
LncRNA WT1-AS/miR-494-3p Regulates Cell Proliferation, Apoptosis, Migration and Invasion via PTEN/PI3K/AKT Signaling Pathway in Non-Small Cell Lung Cancer
Wu C, Yang J, Li R, Lin X, Wu J, Wu J
OncoTargets and Therapy 2021, 14:891-904
Published Date: 9 February 2021
Circular RNA circARPP21 Acts as a Sponge of miR-543 to Suppress Hepatocellular Carcinoma by Regulating LIFR
Gu Y, Wu F, Wang H, Chang J, Wang Y, Li X
OncoTargets and Therapy 2021, 14:879-890
Published Date: 5 February 2021
Expression of p16, p53, and TLR9 in HPV-Associated Head and Neck Squamous Cell Carcinoma: Clinicopathological Correlations and Potential Prognostic Significance
Wang S, Zhuang X, Gao C, Qiao T
OncoTargets and Therapy 2021, 14:867-877
Published Date: 5 February 2021
Screening of Therapeutic Candidate Genes of Quercetin for Cervical Cancer and Analysis of Their Regulatory Network
Li Y, Kou J, Wu T, Zheng P, Chao X
OncoTargets and Therapy 2021, 14:857-866
Published Date: 5 February 2021
Prognostic Value of Programmed Death Ligand-1 Expression on Tumor-Infiltrating Immune Cells in Patients Treated with Cisplatin-Based Combination Adjuvant Chemotherapy Following Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Retrospective Cohort Study
Lee DH, Jeong JY, Song W
OncoTargets and Therapy 2021, 14:845-855
Published Date: 5 February 2021
Combination Therapy with iRGD-antiCD3 and PD-1 Blockade Enhances Antitumor Potency of Cord Blood-Derived T Cells
Zhu M, Wang H, Zhou S, Wei J, Ding N, Shao J, Yu L, Feng Z, Liu B
OncoTargets and Therapy 2021, 14:835-844
Published Date: 5 February 2021
Sinomenine Inhibits the Growth of Ovarian Cancer Cells Through the Suppression of Mitosis by Down-Regulating the Expression and the Activity of CDK1
Qu X, Yu B, Zhu M, Li X, Ma L, Liu C, Zhang Y, Cheng Z
OncoTargets and Therapy 2021, 14:823-834
Published Date: 5 February 2021
Identification of a Six-Gene Signature for Predicting the Overall Survival of Cervical Cancer Patients
Huo X, Zhou X, Peng P, Yu M, Zhang Y, Yang J, Cao D, Sun H, Shen K
OncoTargets and Therapy 2021, 14:809-822
Published Date: 5 February 2021
Triple Discordances in Receptor Status During Breast Cancer Local Progression and Metastases: Case Report and Literature Review [Erratum]
Martuszewski A, Paluszkiewicz P, Nowak M, Szewczyk K, Staszek-Szewczyk U
OncoTargets and Therapy 2021, 14:807-808
Published Date: 4 February 2021
LncRNA FER1L4 Promotes Oral Squamous Cell Carcinoma Progression via Targeting miR-133a-5p/Prx1 Axis
Zhang N, Zeng L, Wang S, Wang R, Yang R, Jin Z, Tao H
OncoTargets and Therapy 2021, 14:795-806
Published Date: 4 February 2021
Development of a Novel Highly Spontaneous Metastatic Model of Esophageal Squamous Cell Carcinoma Using Renal Capsule Technology
Gao P, Liu H, Yang Z, Hui Y, Shi Z, Yang Z, Song M, Yao M, Fan W, Yang J, Hao Y, Fan T
OncoTargets and Therapy 2021, 14:785-793
Published Date: 4 February 2021
Hypofractionated Low-Dose Radiotherapy Combined with Immune Checkpoint Inhibition in Metastatic Solid Tumors
Li D, Zhu W, Zhou J, Peng M, Geng Q, Pu X, Wang M, Jiang H
OncoTargets and Therapy 2021, 14:773-783
Published Date: 4 February 2021
Long Noncoding RNA JAKMIP2-AS1 Promotes the Growth of Colorectal Cancer and Indicates Poor Prognosis
Ma T, Qiao T, Yuan Z, Wang G, Huang R, Wang M, Hu H, Zhu Y, Zou X, Wang X
OncoTargets and Therapy 2021, 14:763-772
Published Date: 3 February 2021
LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis
Gao Q, Huang Q, Li F, Luo F
OncoTargets and Therapy 2021, 14:751-761
Published Date: 3 February 2021
Bone Marrow Mesenchymal Stem Cells-Derived Extracellular Vesicles Promote Proliferation, Invasion and Migration of Osteosarcoma Cells via the lncRNA MALAT1/miR-143/NRSN2/Wnt/β-Catenin Axis
Li F, Chen X, Shang C, Ying Q, Zhou X, Zhu R, Lu H, Hao X, Dong Q, Jiang Z
OncoTargets and Therapy 2021, 14:737-749
Published Date: 2 February 2021
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail
Yuan S, Si W, Zhuang K, Li Y, Zhang Y, Liu J, Yang L, Zhang X
OncoTargets and Therapy 2021, 14:725-736
Published Date: 28 January 2021
Identification of Critical Pathways and Potential Key Genes in Poorly Differentiated Pancreatic Adenocarcinoma
Lu Y, Li D, Liu G, Xiao E, Mu S, Pan Y, Qin F, Zhai Y, Duan S, Li D, Yan G
OncoTargets and Therapy 2021, 14:711-723
Published Date: 27 January 2021
CPNE1 Enhances Colorectal Cancer Cell Growth, Glycolysis, and Drug Resistance Through Regulating the AKT-GLUT1/HK2 Pathway
Wang Y, Pan S, He X, Wang Y, Huang H, Chen J, Zhang Y, Zhang Z, Qin X
OncoTargets and Therapy 2021, 14:699-710
Published Date: 27 January 2021
Chrysin Induced Cell Apoptosis and Inhibited Invasion Through Regulation of TET1 Expression in Gastric Cancer Cells [Corrigendum]
Zhong X, Liu D, Jiang Z, Li C, Chen L, Xia Y, Liu D, Yao Q, Wang D
OncoTargets and Therapy 2021, 14:697-698
Published Date: 26 January 2021
LINC01278 is Highly Expressed in Osteosarcoma and Participates in the Development of Tumors by Mediating the miR-134-5p/KRAS Axis
Zhang GF, Zhou BS, An XC, An FM, Li SH
OncoTargets and Therapy 2021, 14:683-695
Published Date: 26 January 2021
Role of Antizyme Inhibitor Proteins in Cancers and Beyond
Tulluri V, Nemmara VV
OncoTargets and Therapy 2021, 14:667-682
Published Date: 25 January 2021
Circular RNA circSEC24A Promotes Cutaneous Squamous Cell Carcinoma Progression by Regulating miR-1193/MAP3K9 Axis
Lu X, Gan Q, Gan C
OncoTargets and Therapy 2021, 14:653-666
Published Date: 22 January 2021
Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3
Chen B, Dong C, Wang F, Wu J
OncoTargets and Therapy 2021, 14:637-651
Published Date: 22 January 2021
Decitabine and Cisplatin are Synergistic to Exert Anti-Tumor Effect on Gastric Cancer via Inducing Sox2 DNA Demethylation
Zhu Z, Lin S, Wu X, Xu J, Li L, Ye W, Li J, Huang Z
OncoTargets and Therapy 2021, 14:623-636
Published Date: 22 January 2021
Identification and Targeting of Thomsen–Friedenreich and IL1RAP Antigens on Chronic Myeloid Leukemia Stem Cells Using Bi-Specific Antibodies
Eldesouki RE, Wu C, Saleh FM, Mohammed EAM, Younes S, Hassan NE, Brown TC, Alt EU, Robinson JE, Badr FM, Braun SE
OncoTargets and Therapy 2021, 14:609-621
Published Date: 22 January 2021
Understanding Patterns of Brain Metastasis in Triple-Negative Breast Cancer and Exploring Potential Therapeutic Targets
Lv Y, Ma X, Du Y, Feng J
OncoTargets and Therapy 2021, 14:589-607
Published Date: 22 January 2021
Low Expression of Keratin17 is Related to Poor Prognosis in Bladder Cancer
Wu J, Xu H, Ji H, Zhai B, Zhu J, Gao M, Zhu H, Wang X
OncoTargets and Therapy 2021, 14:577-587
Published Date: 19 January 2021
LncRNA ANRIL Regulates Ovarian Cancer Progression and Tumor Stem Cell-Like Characteristics via miR-324-5p/Ran Axis
Wang K, Hu YB, Zhao Y, Ye C
OncoTargets and Therapy 2021, 14:565-576
Published Date: 19 January 2021
Propofol Inhibits the Progression of Cervical Cancer by Regulating HOTAIR/miR-129-5p/RPL14 Axis
Sun N, Zhang W, Liu J, Yang X, Chu Q
OncoTargets and Therapy 2021, 14:551-564
Published Date: 19 January 2021
Gastric Cancer Harboring an ERBB3 Mutation Treated with a Pyrotinib–Irinotecan Combo: A Case Study
Ding K, Chen X, Li Y, Li W, Ye Y, He T, Wang W, Zhang H
OncoTargets and Therapy 2021, 14:545-550
Published Date: 18 January 2021
lncRNA RAET1K Promotes the Progression of Acute Myeloid Leukemia by Targeting miR-503-5p/INPP4B Axis
Li L, Wan D, Li L, Qin Y, Ma W
OncoTargets and Therapy 2021, 14:531-544
Published Date: 18 January 2021
MiR-153-3p Suppresses Cell Proliferation, Invasion and Glycolysis of Thyroid Cancer Through Inhibiting E3F3 Expression
Deng X, Guo B, Fan Y
OncoTargets and Therapy 2021, 14:519-529
Published Date: 18 January 2021
Role of Long Non-Coding RNAs in the Chemoresistance of Gastric Cancer: A Systematic Review
Li Z, Lü M, Zhou Y, Xu L, Jiang Y, Liu Y, Li X, Song M
OncoTargets and Therapy 2021, 14:503-518
Published Date: 18 January 2021
Circ_0067835 Knockdown Enhances the Radiosensitivity of Colorectal Cancer by miR-296-5p/IGF1R Axis
Wang P, Sun Y, Yang Y, Chen Y, Liu H
OncoTargets and Therapy 2021, 14:491-502
Published Date: 18 January 2021
PD-1 Expression in Pre-Treatment Follicular Lymphoma Predicts the Risk of Subsequent High-Grade Transformation
Beck Enemark M, Monrad I, Madsen C, Lystlund Lauridsen K, Honoré B, Plesner TL, Hamilton-Dutoit SJ, d'Amore F, Ludvigsen M
OncoTargets and Therapy 2021, 14:481-489
Published Date: 18 January 2021
Neutral Desorption Extractive Electrospray Ionization Mass Spectrometry Analysis Sputum for Non-Invasive Lung Adenocarcinoma Detection
Zheng Q, Zhang J, Wang X, Zhang W, Xiao Y, Hu S, Xu J
OncoTargets and Therapy 2021, 14:469-479
Published Date: 15 January 2021
MicroRNA-1252-5p Associated with Extracellular Vesicles Enhances Bortezomib Sensitivity in Multiple Myeloma Cells by Targeting Heparanase
Rodrigues-Junior DM, Pelarin MFA, Nader HB, Vettore AL, Pinhal MAS
OncoTargets and Therapy 2021, 14:455-467
Published Date: 15 January 2021
O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness
Chen Y, Liu J, Zhang W, Kadier A, Wang R, Zhang H, Yao X
OncoTargets and Therapy 2021, 14:445-454
Published Date: 15 January 2021
HSDL2 Acts as a Promoter in Pancreatic Cancer by Regulating Cell Proliferation and Lipid Metabolism
Han A, Xu R, Liu Y, Yin X, Lin Z, Yang W
OncoTargets and Therapy 2021, 14:435-444
Published Date: 14 January 2021
Combined Serum DKK3 and Circulating CD133 Cells as Prognostic Biomarkers for Ovarian Cancer Patients
Nie XC, He F, Lan C, Niu JM, Xia P
OncoTargets and Therapy 2021, 14:427-434
Published Date: 14 January 2021
Establishment of a Risk Signature Based on m6A RNA Methylation Regulators That Predicts Poor Prognosis in Renal Cell Carcinoma
Wei J, Qian Y, Tang Y, Ge X, Jiang K, Fang Y, Fu D, Kong X, Xiao Q, Ding K
OncoTargets and Therapy 2021, 14:413-426
Published Date: 14 January 2021
The Value and Clinical Significance of ZNF582 Gene Methylation in the Diagnosis of Cervical Cancer
Zhang C, Fu S, Wang L, Wang F, Wu D, Zhe X, Xin H, Li H, Li D, Jin F, Shao R, Pan Z
OncoTargets and Therapy 2021, 14:403-411
Published Date: 14 January 2021
Long Non-Coding RNA PCED1B-AS1 Promotes the Progression of Clear Cell Renal Cell Carcinoma Through miR-484/ZEB1 Axis
Qin J, Zhu T, Wu W, Chen H, He Y
OncoTargets and Therapy 2021, 14:393-402
Published Date: 13 January 2021
Aberrant SLC6A14 Expression Promotes Proliferation and Metastasis of Colorectal Cancer via Enhancing the JAK2/STAT3 Pathway
Mao H, Sheng J, Jia J, Wang C, Zhang S, Li H, He F
OncoTargets and Therapy 2021, 14:379-392
Published Date: 13 January 2021
LncRNA EWSAT1 Promotes Colorectal Cancer Progression Through Sponging miR-326 to Modulate FBXL20 Expression
Liu J, Huang S, Liao X, Chen Z, Li L, Yu L, Zhan W, Li R
OncoTargets and Therapy 2021, 14:367-378
Published Date: 13 January 2021
CRNDE Contributes Cervical Cancer Progression by Regulating miR-4262/ZEB1 Axis
Ren L, Yang S, Cao Q, Tian J
OncoTargets and Therapy 2021, 14:355-366
Published Date: 13 January 2021
Case Report: Myeloid Sarcoma Development During Treatment for B Cell Lymphoblastic Lymphoma in a Boy with KRAS/NRAS Gene Mutations
Yuan X, Yu U, Chen S, Xu H, Yi M, Jiang X, Song J, Chen X, Chen S, Lin Z, Li C, Wen F, Liu S
OncoTargets and Therapy 2021, 14:347-353
Published Date: 13 January 2021
Prognostic Significance of Preoperative Lymphocyte-to-C-Reactive Protein Ratio in Patients with Non-Metastatic Colorectal Cancer
Ou W, Zhou C, Zhu X, Lin L, Xu Q
OncoTargets and Therapy 2021, 14:337-346
Published Date: 12 January 2021
miR-21 Induces Chemoresistance in Ovarian Cancer Cells via Mediating the Expression and Interaction of CD44v6 and P-gp
Wang Y, Chen G, Dai F, Zhang L, Yuan M, Yang D, Liu S, Cheng Y
OncoTargets and Therapy 2021, 14:325-336
Published Date: 12 January 2021
Further Understanding of Urokinase Plasminogen Activator Overexpression in Urothelial Bladder Cancer Progression, Clinical Outcomes and Potential Therapeutic Targets
Grossmann NC, Schuettfort VM, Pradere B, Moschini M, Quhal F, Mostafaei H, Soria F, Katayama S, Laukhtina E, Mori K, Sari Motlagh R, Poyet C, Abufaraj M, Karakiewicz PI, Shariat SF, D’Andrea D
OncoTargets and Therapy 2021, 14:315-324
Published Date: 13 January 2021
Physalis alkekengi var. franchetii Extracts Exert Antitumor Effects on Non-Small Cell Lung Cancer and Multiple Myeloma by Inhibiting STAT3 Signaling
Fu Y, Zhu F, Ma Z, Lv B, Wang X, Dai C, Ma X, Liu P, Lv H, Chen X, Chen Z, Shen L
OncoTargets and Therapy 2021, 14:301-314
Published Date: 12 January 2021
Lobaplatin Enhances Radioactive 125I Seed-Induced Apoptosis and Anti-Proliferative Effect in Non-Small Cell Lung Cancer by Suppressing the AKT/mTOR Pathway
Rong J, Li D, Li Y
OncoTargets and Therapy 2021, 14:289-300
Published Date: 12 January 2021
The Biological Roles of Exosomal Long Non-Coding RNAs in Cancers
Da M, Jiang H, Xie Y, Jin W, Han S
OncoTargets and Therapy 2021, 14:271-287
Published Date: 12 January 2021
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial–Mesenchymal Transition
Gong L, Cai L, Li G, Cai J, Yi X
OncoTargets and Therapy 2021, 14:255-269
Published Date: 12 January 2021
LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling [Corrigendum]
Wang Q, Liao J, He Z, Su Y, Lin D, Xu L, Xu H, Lin J
OncoTargets and Therapy 2021, 14:253-254
Published Date: 12 January 2021
Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy
Lu Y, Li L, Chen H, Jing X, Wang M, Ge L, Yang J, Zhang M, Tang X
OncoTargets and Therapy 2021, 14:239-251
Published Date: 12 January 2021
Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells
Wu J, Sun L, Liu T, Dong G
OncoTargets and Therapy 2021, 14:221-237
Published Date: 11 January 2021
The Plasma Concentration of D-Dimer is Associated with Neoadjuvant-Chemotherapy Efficacy and the Prognosis in Osteosarcoma
Huang Y, Shen Z, Yao Y, He A, Min D
OncoTargets and Therapy 2021, 14:213-220
Published Date: 11 January 2021
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes
Li R, Li Y, Qin H, Li S
OncoTargets and Therapy 2021, 14:199-211
Published Date: 13 January 2021
A Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells
Lv X, Zhang J, Zhang J, Guan W, Ren W, Liu Y, Xu G
OncoTargets and Therapy 2021, 14:187-198
Published Date: 8 January 2021
Multi Cytogenetic Changes in a Patient as Co-Existing MDS and CLL Progresses
Li X, Ma J, Wang L, Yan S, Li F, Wang L, Wang L, Li G, Ma D, Li H
OncoTargets and Therapy 2021, 14:177-186
Published Date: 8 January 2021
Upregulation of miR-137 Expression Suppresses Tumor Growth and Progression via Interacting with DNMT3a Through Inhibiting the PTEN/Akt Signaling in HCC
Wang J, Wang Z, Yuan J, Wang Q, Shen X
OncoTargets and Therapy 2021, 14:165-176
Published Date: 8 January 2021
LncRNA DDX11-AS1 Exerts Oncogenic Roles in Glioma Through Regulating miR-499b-5p/RWDD4 Axis
Zheng Y, Xie J, Xu X, Yang X, Zhou Y, Yao Q, Xiong Y
OncoTargets and Therapy 2021, 14:157-164
Published Date: 8 January 2021
ALYREF Drives Cancer Cell Proliferation Through an ALYREF-MYC Positive Feedback Loop in Glioblastoma
Wang J, Li Y, Xu B, Dong J, Zhao H, Zhao D, Wu Y
OncoTargets and Therapy 2021, 14:145-155
Published Date: 8 January 2021
Rare Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review
Wang N, Dong SS, Wu CL, Wang Y, Meng L, Ren Y, Cui XB, Li M, Qi Y
OncoTargets and Therapy 2021, 14:139-144
Published Date: 8 January 2021
PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma
Li H, Liu Q, Xiao K, He Z, Wu C, Sun J, Chen X, Chen S, Yang J, Ma Q, Su J
OncoTargets and Therapy 2021, 14:125-138
Published Date: 8 January 2021
Exosomal miR-638 Inhibits Hepatocellular Carcinoma Progression by Targeting SP1 [Retraction]
Yang J, Li B, Zhao S, Du H, Du Y
OncoTargets and Therapy 2021, 14:123-124
Published Date: 8 January 2021
Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene
Luo Y, Yu P, Zhao J, Guo Q, Fan B, Diao Y, Jin Y, Wu J, Zhang C
OncoTargets and Therapy 2021, 14:111-122
Published Date: 7 January 2021
Circ_0007444 Inhibits the Progression of Ovarian Cancer via Mediating the miR-570-3p/PTEN Axis
Wu X, Liu D, Wang S, Liu J
OncoTargets and Therapy 2021, 14:97-110
Published Date: 7 January 2021
Circ_0006404 Accelerates Prostate Cancer Progression Through Regulating miR-1299/CFL2 Signaling
Li P, Wang Z, Li S, Wang L
OncoTargets and Therapy 2021, 14:83-95
Published Date: 6 January 2021
Silencing of MicroRNA-503 in Rat Mesenchymal Stem Cells Exerts Potent Antitumorigenic Effects in Lung Cancer Cells
Huang B, Feng Z, Zhu L, Zhang S, Duan J, Zhao C, Zhang X
OncoTargets and Therapy 2021, 14:67-81
Published Date: 6 January 2021
Aberrant Factors of Fibrinolysis and Coagulation in Pancreatic Cancer
Fang L, Xu Q, Qian J, Zhou JY
OncoTargets and Therapy 2021, 14:53-65
Published Date: 6 January 2021
Clinicopathological and Prognostic Significance of Immunoscore and PD-L1 in Intrahepatic Cholangiocarcinoma
Wu H, Wei Y, Jian M, Lu H, Song Q, Hao L, Yue Y
OncoTargets and Therapy 2021, 14:39-51
Published Date: 6 January 2021
Prognostic Value of Pretreatment Serum Cystatin C Level in Nasopharyngeal Carcinoma Patients in the Intensity-modulated Radiotherapy Era
Tan XR, Huang SY, Gong S, Chen Y, Yang XJ, He QM, He SW, Liu N, Li YQ
OncoTargets and Therapy 2021, 14:29-37
Published Date: 6 January 2021
MiRNA-1225 Inhibits Osteosarcoma Tumor Growth and Progression by Targeting YWHAZ
Gong Y, Wei Z, Liu J
OncoTargets and Therapy 2021, 14:15-27
Published Date: 6 January 2021
Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression
He J, Guan J, Liao S, Wu Z, Liu B, Mo H, Yuan Z
OncoTargets and Therapy 2021, 14:1-13
Published Date: 6 January 2021