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OncoTargets and Therapy
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Archive: Volume 14, 2021
Chrysin Induced Cell Apoptosis and Inhibited Invasion Through Regulation of TET1 Expression in Gastric Cancer Cells [Corrigendum]
Zhong X, Liu D, Jiang Z, Li C, Chen L, Xia Y, Liu D, Yao Q, Wang D
OncoTargets and Therapy 2021, 14:697-698
Published Date: 26 January 2021
LINC01278 is Highly Expressed in Osteosarcoma and Participates in the Development of Tumors by Mediating the miR-134-5p/KRAS Axis
Zhang GF, Zhou BS, An XC, An FM, Li SH
OncoTargets and Therapy 2021, 14:683-695
Published Date: 26 January 2021
Role of Antizyme Inhibitor Proteins in Cancers and Beyond
Tulluri V, Nemmara VV
OncoTargets and Therapy 2021, 14:667-682
Published Date: 25 January 2021
Circular RNA circSEC24A Promotes Cutaneous Squamous Cell Carcinoma Progression by Regulating miR-1193/MAP3K9 Axis
Lu X, Gan Q, Gan C
OncoTargets and Therapy 2021, 14:653-666
Published Date: 22 January 2021
Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3
Chen B, Dong C, Wang F, Wu J
OncoTargets and Therapy 2021, 14:637-651
Published Date: 22 January 2021
Decitabine and Cisplatin are Synergistic to Exert Anti-Tumor Effect on Gastric Cancer via Inducing Sox2 DNA Demethylation
Zhu Z, Lin S, Wu X, Xu J, Li L, Ye W, Li J, Huang Z
OncoTargets and Therapy 2021, 14:623-636
Published Date: 22 January 2021
Identification and Targeting of Thomsen–Friedenreich and IL1RAP Antigens on Chronic Myeloid Leukemia Stem Cells Using Bi-Specific Antibodies
Eldesouki RE, Wu C, Saleh FM, Mohammed EAM, Younes S, Hassan NE, Brown TC, Alt EU, Robinson JE, Badr FM, Braun SE
OncoTargets and Therapy 2021, 14:609-621
Published Date: 22 January 2021
Understanding Patterns of Brain Metastasis in Triple-Negative Breast Cancer and Exploring Potential Therapeutic Targets
Lv Y, Ma X, Du Y, Feng J
OncoTargets and Therapy 2021, 14:589-607
Published Date: 22 January 2021
Low Expression of Keratin17 is Related to Poor Prognosis in Bladder Cancer
Wu J, Xu H, Ji H, Zhai B, Zhu J, Gao M, Zhu H, Wang X
OncoTargets and Therapy 2021, 14:577-587
Published Date: 19 January 2021
LncRNA ANRIL Regulates Ovarian Cancer Progression and Tumor Stem Cell-Like Characteristics via miR-324-5p/Ran Axis
Wang K, Hu YB, Zhao Y, Ye C
OncoTargets and Therapy 2021, 14:565-576
Published Date: 19 January 2021
Propofol Inhibits the Progression of Cervical Cancer by Regulating HOTAIR/miR-129-5p/RPL14 Axis
Sun N, Zhang W, Liu J, Yang X, Chu Q
OncoTargets and Therapy 2021, 14:551-564
Published Date: 19 January 2021
Gastric Cancer Harboring an ERBB3 Mutation Treated with a Pyrotinib–Irinotecan Combo: A Case Study
Ding K, Chen X, Li Y, Li W, Ye Y, He T, Wang W, Zhang H
OncoTargets and Therapy 2021, 14:545-550
Published Date: 18 January 2021
lncRNA RAET1K Promotes the Progression of Acute Myeloid Leukemia by Targeting miR-503-5p/INPP4B Axis
Li L, Wan D, Li L, Qin Y, Ma W
OncoTargets and Therapy 2021, 14:531-544
Published Date: 18 January 2021
MiR-153-3p Suppresses Cell Proliferation, Invasion and Glycolysis of Thyroid Cancer Through Inhibiting E3F3 Expression
Deng X, Guo B, Fan Y
OncoTargets and Therapy 2021, 14:519-529
Published Date: 18 January 2021
Role of Long Non-Coding RNAs in the Chemoresistance of Gastric Cancer: A Systematic Review
Li Z, Lü M, Zhou Y, Xu L, Jiang Y, Liu Y, Li X, Song M
OncoTargets and Therapy 2021, 14:503-518
Published Date: 18 January 2021
Circ_0067835 Knockdown Enhances the Radiosensitivity of Colorectal Cancer by miR-296-5p/IGF1R Axis
Wang P, Sun Y, Yang Y, Chen Y, Liu H
OncoTargets and Therapy 2021, 14:491-502
Published Date: 18 January 2021
PD-1 Expression in Pre-Treatment Follicular Lymphoma Predicts the Risk of Subsequent High-Grade Transformation
Beck Enemark M, Monrad I, Madsen C, Lystlund Lauridsen K, Honoré B, Plesner TL, Hamilton-Dutoit SJ, d'Amore F, Ludvigsen M
OncoTargets and Therapy 2021, 14:481-489
Published Date: 18 January 2021
Neutral Desorption Extractive Electrospray Ionization Mass Spectrometry Analysis Sputum for Non-Invasive Lung Adenocarcinoma Detection
Zheng Q, Zhang J, Wang X, Zhang W, Xiao Y, Hu S, Xu J
OncoTargets and Therapy 2021, 14:469-479
Published Date: 15 January 2021
MicroRNA-1252-5p Associated with Extracellular Vesicles Enhances Bortezomib Sensitivity in Multiple Myeloma Cells by Targeting Heparanase
Rodrigues-Junior DM, Pelarin MFA, Nader HB, Vettore AL, Pinhal MAS
OncoTargets and Therapy 2021, 14:455-467
Published Date: 15 January 2021
O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness
Chen Y, Liu J, Zhang W, Kadier A, Wang R, Zhang H, Yao X
OncoTargets and Therapy 2021, 14:445-454
Published Date: 15 January 2021
HSDL2 Acts as a Promoter in Pancreatic Cancer by Regulating Cell Proliferation and Lipid Metabolism
Han A, Xu R, Liu Y, Yin X, Lin Z, Yang W
OncoTargets and Therapy 2021, 14:435-444
Published Date: 14 January 2021
Combined Serum DKK3 and Circulating CD133 Cells as Prognostic Biomarkers for Ovarian Cancer Patients
Nie XC, He F, Lan C, Niu JM, Xia P
OncoTargets and Therapy 2021, 14:427-434
Published Date: 14 January 2021
Establishment of a Risk Signature Based on m6A RNA Methylation Regulators That Predicts Poor Prognosis in Renal Cell Carcinoma
Wei J, Qian Y, Tang Y, Ge X, Jiang K, Fang Y, Fu D, Kong X, Xiao Q, Ding K
OncoTargets and Therapy 2021, 14:413-426
Published Date: 14 January 2021
The Value and Clinical Significance of ZNF582 Gene Methylation in the Diagnosis of Cervical Cancer
Zhang C, Fu S, Wang L, Wang F, Wu D, Zhe X, Xin H, Li H, Li D, Jin F, Shao R, Pan Z
OncoTargets and Therapy 2021, 14:403-411
Published Date: 14 January 2021
Long Non-Coding RNA PCED1B-AS1 Promotes the Progression of Clear Cell Renal Cell Carcinoma Through miR-484/ZEB1 Axis
Qin J, Zhu T, Wu W, Chen H, He Y
OncoTargets and Therapy 2021, 14:393-402
Published Date: 13 January 2021
Aberrant SLC6A14 Expression Promotes Proliferation and Metastasis of Colorectal Cancer via Enhancing the JAK2/STAT3 Pathway
Mao H, Sheng J, Jia J, Wang C, Zhang S, Li H, He F
OncoTargets and Therapy 2021, 14:379-392
Published Date: 13 January 2021
LncRNA EWSAT1 Promotes Colorectal Cancer Progression Through Sponging miR-326 to Modulate FBXL20 Expression
Liu J, Huang S, Liao X, Chen Z, Li L, Yu L, Zhan W, Li R
OncoTargets and Therapy 2021, 14:367-378
Published Date: 13 January 2021
CRNDE Contributes Cervical Cancer Progression by Regulating miR-4262/ZEB1 Axis
Ren L, Yang S, Cao Q, Tian J
OncoTargets and Therapy 2021, 14:355-366
Published Date: 13 January 2021
Case Report: Myeloid Sarcoma Development During Treatment for B Cell Lymphoblastic Lymphoma in a Boy with KRAS/NRAS Gene Mutations
Yuan X, Yu U, Chen S, Xu H, Yi M, Jiang X, Song J, Chen X, Chen S, Lin Z, Li C, Wen F, Liu S
OncoTargets and Therapy 2021, 14:347-353
Published Date: 13 January 2021
Prognostic Significance of Preoperative Lymphocyte-to-C-Reactive Protein Ratio in Patients with Non-Metastatic Colorectal Cancer
Ou W, Zhou C, Zhu X, Lin L, Xu Q
OncoTargets and Therapy 2021, 14:337-346
Published Date: 12 January 2021
miR-21 Induces Chemoresistance in Ovarian Cancer Cells via Mediating the Expression and Interaction of CD44v6 and P-gp
Wang Y, Chen G, Dai F, Zhang L, Yuan M, Yang D, Liu S, Cheng Y
OncoTargets and Therapy 2021, 14:325-336
Published Date: 12 January 2021
Further Understanding of Urokinase Plasminogen Activator Overexpression in Urothelial Bladder Cancer Progression, Clinical Outcomes and Potential Therapeutic Targets
Grossmann NC, Schuettfort VM, Pradere B, Moschini M, Quhal F, Mostafaei H, Soria F, Katayama S, Laukhtina E, Mori K, Sari Motlagh R, Poyet C, Abufaraj M, Karakiewicz PI, Shariat SF, D’Andrea D
OncoTargets and Therapy 2021, 14:315-324
Published Date: 13 January 2021
Physalis alkekengi var. franchetii Extracts Exert Antitumor Effects on Non-Small Cell Lung Cancer and Multiple Myeloma by Inhibiting STAT3 Signaling
Fu Y, Zhu F, Ma Z, Lv B, Wang X, Dai C, Ma X, Liu P, Lv H, Chen X, Chen Z, Shen L
OncoTargets and Therapy 2021, 14:301-314
Published Date: 12 January 2021
Lobaplatin Enhances Radioactive 125I Seed-Induced Apoptosis and Anti-Proliferative Effect in Non-Small Cell Lung Cancer by Suppressing the AKT/mTOR Pathway
Rong J, Li D, Li Y
OncoTargets and Therapy 2021, 14:289-300
Published Date: 12 January 2021
The Biological Roles of Exosomal Long Non-Coding RNAs in Cancers
Da M, Jiang H, Xie Y, Jin W, Han S
OncoTargets and Therapy 2021, 14:271-287
Published Date: 12 January 2021
GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial–Mesenchymal Transition
Gong L, Cai L, Li G, Cai J, Yi X
OncoTargets and Therapy 2021, 14:255-269
Published Date: 12 January 2021
LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling [Corrigendum]
Wang Q, Liao J, He Z, Su Y, Lin D, Xu L, Xu H, Lin J
OncoTargets and Therapy 2021, 14:253-254
Published Date: 12 January 2021
Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy
Lu Y, Li L, Chen H, Jing X, Wang M, Ge L, Yang J, Zhang M, Tang X
OncoTargets and Therapy 2021, 14:239-251
Published Date: 12 January 2021
Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells
Wu J, Sun L, Liu T, Dong G
OncoTargets and Therapy 2021, 14:221-237
Published Date: 11 January 2021
The Plasma Concentration of D-Dimer is Associated with Neoadjuvant-Chemotherapy Efficacy and the Prognosis in Osteosarcoma
Huang Y, Shen Z, Yao Y, He A, Min D
OncoTargets and Therapy 2021, 14:213-220
Published Date: 11 January 2021
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes
Li R, Li Y, Qin H, Li S
OncoTargets and Therapy 2021, 14:199-211
Published Date: 13 January 2021
A Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells
Lv X, Zhang J, Zhang J, Guan W, Ren W, Liu Y, Xu G
OncoTargets and Therapy 2021, 14:187-198
Published Date: 8 January 2021
Multi Cytogenetic Changes in a Patient as Co-Existing MDS and CLL Progresses
Li X, Ma J, Wang L, Yan S, Li F, Wang L, Wang L, Li G, Ma D, Li H
OncoTargets and Therapy 2021, 14:177-186
Published Date: 8 January 2021
Upregulation of miR-137 Expression Suppresses Tumor Growth and Progression via Interacting with DNMT3a Through Inhibiting the PTEN/Akt Signaling in HCC
Wang J, Wang Z, Yuan J, Wang Q, Shen X
OncoTargets and Therapy 2021, 14:165-176
Published Date: 8 January 2021
LncRNA DDX11-AS1 Exerts Oncogenic Roles in Glioma Through Regulating miR-499b-5p/RWDD4 Axis
Zheng Y, Xie J, Xu X, Yang X, Zhou Y, Yao Q, Xiong Y
OncoTargets and Therapy 2021, 14:157-164
Published Date: 8 January 2021
ALYREF Drives Cancer Cell Proliferation Through an ALYREF-MYC Positive Feedback Loop in Glioblastoma
Wang J, Li Y, Xu B, Dong J, Zhao H, Zhao D, Wu Y
OncoTargets and Therapy 2021, 14:145-155
Published Date: 8 January 2021
Rare Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review
Wang N, Dong SS, Wu CL, Wang Y, Meng L, Ren Y, Cui XB, Li M, Qi Y
OncoTargets and Therapy 2021, 14:139-144
Published Date: 8 January 2021
PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma
Li H, Liu Q, Xiao K, He Z, Wu C, Sun J, Chen X, Chen S, Yang J, Ma Q, Su J
OncoTargets and Therapy 2021, 14:125-138
Published Date: 8 January 2021
Exosomal miR-638 Inhibits Hepatocellular Carcinoma Progression by Targeting SP1 [Retraction]
Yang J, Li B, Zhao S, Du H, Du Y
OncoTargets and Therapy 2021, 14:123-124
Published Date: 8 January 2021
Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene
Luo Y, Yu P, Zhao J, Guo Q, Fan B, Diao Y, Jin Y, Wu J, Zhang C
OncoTargets and Therapy 2021, 14:111-122
Published Date: 7 January 2021
Circ_0007444 Inhibits the Progression of Ovarian Cancer via Mediating the miR-570-3p/PTEN Axis
Wu X, Liu D, Wang S, Liu J
OncoTargets and Therapy 2021, 14:97-110
Published Date: 7 January 2021
Circ_0006404 Accelerates Prostate Cancer Progression Through Regulating miR-1299/CFL2 Signaling
Li P, Wang Z, Li S, Wang L
OncoTargets and Therapy 2021, 14:83-95
Published Date: 6 January 2021
Silencing of MicroRNA-503 in Rat Mesenchymal Stem Cells Exerts Potent Antitumorigenic Effects in Lung Cancer Cells
Huang B, Feng Z, Zhu L, Zhang S, Duan J, Zhao C, Zhang X
OncoTargets and Therapy 2021, 14:67-81
Published Date: 6 January 2021
Aberrant Factors of Fibrinolysis and Coagulation in Pancreatic Cancer
Fang L, Xu Q, Qian J, Zhou JY
OncoTargets and Therapy 2021, 14:53-65
Published Date: 6 January 2021
Clinicopathological and Prognostic Significance of Immunoscore and PD-L1 in Intrahepatic Cholangiocarcinoma
Wu H, Wei Y, Jian M, Lu H, Song Q, Hao L, Yue Y
OncoTargets and Therapy 2021, 14:39-51
Published Date: 6 January 2021
Prognostic Value of Pretreatment Serum Cystatin C Level in Nasopharyngeal Carcinoma Patients in the Intensity-modulated Radiotherapy Era
Tan XR, Huang SY, Gong S, Chen Y, Yang XJ, He QM, He SW, Liu N, Li YQ
OncoTargets and Therapy 2021, 14:29-37
Published Date: 6 January 2021
MiRNA-1225 Inhibits Osteosarcoma Tumor Growth and Progression by Targeting YWHAZ
Gong Y, Wei Z, Liu J
OncoTargets and Therapy 2021, 14:15-27
Published Date: 6 January 2021
Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression
He J, Guan J, Liao S, Wu Z, Liu B, Mo H, Yuan Z
OncoTargets and Therapy 2021, 14:1-13
Published Date: 6 January 2021