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OncoTargets and Therapy


Archive: Volume 14, 2021

Roles of N6‐Methyladenosine Demethylase FTO in Malignant Tumors Progression

Zheng QK, Ma C, ullah I, Hu K, Ma RJ, Zhang N, Sun ZG

OncoTargets and Therapy 2021, 14:4837-4846

Published Date: 16 September 2021

A Metastatic Cervical Adenocarcinoma Patient Carrying HER2 G292R Achieved Complete Response Upon Pyrotinib Treatment

Liu J, Zhuo Y, Wang F, Li Z, Lin Y, Li L, Pan J, Song Y, Du H, Li C, Xu Q

OncoTargets and Therapy 2021, 14:4833-4836

Published Date: 16 September 2021

Clinical Utility of Olaparib in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Review of Current Evidence and Patient Selection

LeVee A, Lin CY, Posadas E, Figlin R, Bhowmick NA, Di Vizio D, Ellis L, Rosser CJ, Freeman MR, Theodorescu D, Freedland SJ, Gong J

OncoTargets and Therapy 2021, 14:4819-4832

Published Date: 15 September 2021

High Tumor Mutation Burden and DNA Repair Gene Mutations are Associated with Primary Resistance to Crizotinib in ALK-Rearranged Lung Cancer

Xiao D, Deng Q, He D, Huang Y, Liang W, Wang F, Yang H

OncoTargets and Therapy 2021, 14:4809-4817

Published Date: 15 September 2021

Clinical and Pathologic Complete Response to Gefitinib in a Patient with SqCLC Harboring EGFR p.E746_S752delinsV Mutation

Zhuang W, Zhang C, Tang Y, Tian D, Lan Z, Zeng C, Qiao G

OncoTargets and Therapy 2021, 14:4805-4808

Published Date: 15 September 2021

A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells

Chen W, Wu S, Huang Y, Zhang T, Dong H, Zheng X, Chen T, Gong X, Liu G, Zhao X

OncoTargets and Therapy 2021, 14:4791-4804

Published Date: 10 September 2021

CircPTCH1 Promotes Migration in Lung Cancer by Regulating MYCN Expression Through miR-34c-5p

Shen Z, Sun S

OncoTargets and Therapy 2021, 14:4779-4789

Published Date: 10 September 2021

TFF-1 Functions to Suppress Multiple Phenotypes Associated with Lung Cancer Progression

Minegishi K, Dobashi Y, Tsubochi H, Hagiwara K, Ishibashi Y, Nomura S, Nakamura R, Ohmoto Y, Endo S

OncoTargets and Therapy 2021, 14:4761-4777

Published Date: 10 September 2021

Carbon-Ion Beam Irradiation and the miR-200c Mimic Effectively Eradicate Pancreatic Cancer Stem Cells Under in vitro and in vivo Conditions

Sai S, Kim EH, Koom WS, Vares G, Suzuki M, Yamada S, Hayashi M

OncoTargets and Therapy 2021, 14:4749-4760

Published Date: 16 September 2021

LncRNA SNHG16 Drives Proliferation and Invasion of Papillary Thyroid Cancer Through Modulation of miR-497 [Retraction]

Wen Q, Zhao L, Wang T, Lv N, Cheng X, Zhang G, Bai L

OncoTargets and Therapy 2021, 14:4747-4748

Published Date: 9 September 2021

Long Noncoding RNA DLEU1 Aggravates Glioma Progression via the miR-421/MEF2D Axis [Retraction]

Feng L, He M, Rao M, Diao J, Zhu Y

OncoTargets and Therapy 2021, 14:4735-4736

Published Date: 9 September 2021

Long Non-Coding RNA Duxap8 Facilitates Cell Proliferation and Induces Apoptosis in Colorectal Cancer via miR-519b/ZNF277 Axis

Liang H, Wang J, Zhang P, Yang W, Yang Y, Zhi Y, Wu W, Dong X

OncoTargets and Therapy 2021, 14:4693-4703

Published Date: 1 September 2021

Testing for EGFR Mutations and ALK Rearrangements in Advanced Non-Small-Cell Lung Cancer: Considerations for Countries in Emerging Markets

Dalurzo ML, Avilés-Salas A, Soares FA, Hou Y, Li Y, Stroganova A, Öz B, Abdillah A, Wan H, Choi YL

OncoTargets and Therapy 2021, 14:4671-4692

Published Date: 1 September 2021

ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer [Corrigendum]

Weng M, Zhang H, Hou W, Sun Z, Zhong J, Miao C

OncoTargets and Therapy 2021, 14:4641-4643

Published Date: 31 August 2021

Effect of Long Non-Coding RNA AOC4P on Gastrointestinal Stromal Tumor Cells [Retraction]

Hu JC, Wang Q, Jiang LX, Cai L, Zhai HY, Yao ZW, Zhang ML, Feng Y

OncoTargets and Therapy 2021, 14:4639-4640

Published Date: 30 August 2021

MicroRNA-200b Acts as a Tumor Suppressor in Osteosarcoma via Targeting ZEB1 [Retraction]

Li Y, Zeng C, Tu M, Jiang W, Dai Z, Hu Y, Deng Z, Xiao W

OncoTargets and Therapy 2021, 14:4637-4638

Published Date: 30 August 2021

Diagnosis of NUT Carcinoma Despite False-Negative Next-Generation Sequencing Results: A Case Report and Literature Review

Wang X, Wang J, Luo X, Lu J, Wang L, Li Q, Wang EH

OncoTargets and Therapy 2021, 14:4621-4633

Published Date: 27 August 2021

Daam1 Overexpression Promotes Gastric Cancer Progression and Regulates ERK and AKT Signaling Pathways

Zhang Y, Bai X, Zhang Y, Li Y

OncoTargets and Therapy 2021, 14:4609-4619

Published Date: 27 August 2021

A Case Report of Targeted Therapy with Anlotinib in a Patient with Advanced Breast Metaplastic Carcinoma

Zou J, Yang X, Duan J, Wang J, Yang Z, Luo D, Liu L, Chen J, Nie J

OncoTargets and Therapy 2021, 14:4599-4607

Published Date: 27 August 2021

Osimertinib in EGFR-Mutated Lung Cancer: A Review of the Existing and Emerging Clinical Data

Lee CS, Milone M, Seetharamu N

OncoTargets and Therapy 2021, 14:4579-4597

Published Date: 26 August 2021

A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

Liu S, Li D, Liu J, Wang H, Horecny I, Shen R, Zhang R, Wu H, Hu Q, Zhao P, Zhang F, Yan Y, Feng J, Zhuang L, Li J, Zhang L, Tao W

OncoTargets and Therapy 2021, 14:4561-4574

Published Date: 24 August 2021

Simultaneous Follicular Lymphoma and Myelofibrosis: Report of a Case with Review of the Literature

Kong L, Li J, Wang RC, Kang L, Wei Q, Li Y

OncoTargets and Therapy 2021, 14:4551-4559

Published Date: 24 August 2021

Potential Role of Pleural Fluid Cytokine Profile in Myelomatous Pleural Effusions

Xu J, Gao L, Yan M, Wang B, Song Z, Liu H, Sun K, Nong L, Wang M, Cen X

OncoTargets and Therapy 2021, 14:4545-4550

Published Date: 24 August 2021

Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells

Tsai SC, Wu WC, Yang JS

OncoTargets and Therapy 2021, 14:4523-4536

Published Date: 21 August 2021

Clinical Utility of Fedratinib in Myelofibrosis

Waksal JA, Tremblay D, Mascarenhas J

OncoTargets and Therapy 2021, 14:4509-4521

Published Date: 21 August 2021

Efficacy and Safety of Apatinib for Elderly Patients with Advanced or Metastatic Gastric Cancer After Failure of at Least First-Line Chemotherapy: A Multi-Center, Single-Arm, Phase II Study

Ren D, Wang G, Zhang Y, Kan J, Dong Q, Zhao J, Ji F, Li H, Luo Y, Lin M, Li G, Liu Z, Ma X, Guo Q, Zhao F, Shen G, Zhao J

OncoTargets and Therapy 2021, 14:4499-4508

Published Date: 18 August 2021

Endometrial Tumors with MSI-H and dMMR Share a Similar Tumor Immune Microenvironment

Song Y, Gu Y, Hu X, Wang M, He Q, Li Y

OncoTargets and Therapy 2021, 14:4485-4497

Published Date: 16 August 2021

Advances in Immunotherapy of Malignant Pleural Mesothelioma

Liao D, Yu Y, Mei Q, Wang Z, Li X, Jia Y, Kong F

OncoTargets and Therapy 2021, 14:4477-4484

Published Date: 14 August 2021

Prognostic Value of miR-1826 in Prostate Cancer and Its Regulatory Effect on Tumor Progression

Liu Y, Liu J, Han X, Mou L

OncoTargets and Therapy 2021, 14:4467-4475

Published Date: 13 August 2021

A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer

Qu Z, Liu J, Zhu L, Zhou Q

OncoTargets and Therapy 2021, 14:4451-4465

Published Date: 12 August 2021

Subgroup Analysis by Liver Metastasis in the FRESCO Trial Comparing Fruquintinib versus Placebo Plus Best Supportive Care in Chinese Patients with Metastatic Colorectal Cancer

Qin S, Xu RH, Shen L, Xu J, Bai Y, Yang L, Deng Y, Chen ZD, Zhong H, Pan H, Guo W, Shu Y, Yuan Y, Zhou J, Xu N, Liu T, Ma D, Wu C, Cheng Y, Chen D, Li W, Sun S, Yu Z, Cao P, Chen H, Wang J, Wang S, Wang H, Wang N, Zhang B, Zhang Q, Su W, Guo X, Li J

OncoTargets and Therapy 2021, 14:4439-4450

Published Date: 11 August 2021

TP53 Mutation Related and Directly Regulated lncRNA Prognosis Markers in Hepatocellular Carcinoma

Zhang X, Fu Z, Zhang X

OncoTargets and Therapy 2021, 14:4427-4437

Published Date: 10 August 2021

Long Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis

Zhang M, Zhu W, Haeryfar M, Jiang S, Jiang X, Chen W, Li J

OncoTargets and Therapy 2021, 14:4415-4426

Published Date: 10 August 2021

Choriocarcinoma Masquerading as Lung Abscess or Lung Cancer: A Case with Atypical Imaging Findings

Gu Q, Yan S, Lin J, Wu X, Chen L, Gan M, Luo H, Lv D, Lin L

OncoTargets and Therapy 2021, 14:4407-4414

Published Date: 10 August 2021

High Matrix Metalloproteinase 28 Expression is Associated with Poor Prognosis in Pancreatic Adenocarcinoma

Liu N, Zhong L, Ni G, Lin J, Xie L, Li T, Dan H, Chen Q

OncoTargets and Therapy 2021, 14:4391-4406

Published Date: 10 August 2021

Targeting c-MET to Enhance the Efficacy of Olaparib in Prostate Cancer

Wang Z, Dai Z, Wang B, Gao Y, Gao X, Wang L, Zhou S, Yang L, Qiu X, Liu Z

OncoTargets and Therapy 2021, 14:4383-4389

Published Date: 4 August 2021

The Anti-Cancer Effect of Four Curcumin Analogues on Human Glioma Cells

Luo SM, Wu YP, Huang LC, Huang SM, Hueng DY

OncoTargets and Therapy 2021, 14:4345-4359

Published Date: 4 August 2021

miR-765 Acts as a Tumor Promoter and Indicates Poor Prognosis in Non-Small Cell Lung Cancer

Wang J, Wang L, Zhang C

OncoTargets and Therapy 2021, 14:4335-4343

Published Date: 4 August 2021

Immunotherapy-Related Cystitis: Case Report and Review of the Literature

Zhu L, Wang Z, Stebbing J, Wang Z, Peng L

OncoTargets and Therapy 2021, 14:4321-4328

Published Date: 31 July 2021

LncRNA MIR205HG Drives Esophageal Squamous Cell Carcinoma Progression by Regulating miR-214/SOX4 Axis [Corrigendum]

Li H, Jia J, Yang L, Chu J, Sheng J, Wang C, Meng W, Jia Z, Yin H, Wan J, He F

OncoTargets and Therapy 2021, 14:4319-4320

Published Date: 2 August 2021

Glypican-1 Overexpression in Different Types of Breast Cancers

Alshammari FO, Al-Saraireh YM, Youssef AM, AL-sarayra YM, Alrawashdeh HM

OncoTargets and Therapy 2021, 14:4309-4318

Published Date: 30 July 2021

Sorafenib in the Treatment of Virus-Related HCC: Differences Between HCV and HBV

De Matteis S, Ghetti M, Gramantieri L, Marisi G, Casadei-Gardini A

OncoTargets and Therapy 2021, 14:4305-4308

Published Date: 30 July 2021

Gallbladder Adenosquamous Cancer with Situs Inversus Totalis: A Case Report and Literature Review

Huang J, Yang H, Wang M, Zhao X, Shao S, Zhang F, Que R, Hu Q, Liang T

OncoTargets and Therapy 2021, 14:4299-4304

Published Date: 28 July 2021

LINC00152 Promotes the Growth and Invasion of Oral Squamous Cell Carcinoma by Regulating miR-139-5p [Retraction]

Li M, Ning J, Li Z, Wang J, Zhao C, Wang L

OncoTargets and Therapy 2021, 14:4297-4298

Published Date: 29 July 2021

SQLE Mediates Metabolic Reprogramming to Promote LN Metastasis in Castration-Resistant Prostate Cancer

Xu Z, Huang L, Dai T, Pei X, Xia L, Zeng G, Ye M, Liu K, Zeng F, Han W, Jiang S

OncoTargets and Therapy 2021, 14:4285-4295

Published Date: 24 July 2021

Expression of B7-H3 Correlates with PD-L1 and Poor Prognosis in Patients with Cervical Cancer

Zhang Q, Zong L, Zhang H, Xie W, Yang F, Sun W, Cui B, Zhang Y

OncoTargets and Therapy 2021, 14:4275-4283

Published Date: 23 July 2021

Heterochronous Metastases of Lung Adenocarcinoma to Pancreas and Liver: A Case Report from Pathological Perspectives

Zhang B, Hu Q, Yu J, Wang J, Yang H, Lou J, Cai G, Huang H, Xu M, Xiao Z, Zhang Y

OncoTargets and Therapy 2021, 14:4269-4273

Published Date: 22 July 2021

ILT4 in Colorectal Cancer Cells Induces Suppressive T Cell Contexture and Disease Progression

Yang Z, Gao A, Shi W, Wang J, Zhang X, Xu Z, Xu T, Zheng Y, Sun Y, Yang F

OncoTargets and Therapy 2021, 14:4239-4254

Published Date: 20 July 2021

A Case of Pulmonary Embolism with Sarcomatoid Malignant Pleural Mesothelioma with Long-Term Pleural Effusion

Gu R, Jiang L, Duan T, Chen C, Wu S, Mu D

OncoTargets and Therapy 2021, 14:4231-4237

Published Date: 16 July 2021

The Regulatory Role of PRRX1 in Cancer Epithelial-Mesenchymal Transition

Du W, Liu X, Yang M, Wang W, Sun J

OncoTargets and Therapy 2021, 14:4223-4229

Published Date: 16 July 2021

CDH11 Regulates Adhesion and Transcellular Migration of Tongue Squamous Cell Carcinoma

Zheng BT, Li QL, Lan T, Xie J, Lu YG, Zheng DL, Su BH

OncoTargets and Therapy 2021, 14:4211-4222

Published Date: 16 July 2021

Expression and Diagnostic Value of tRNA-Derived Fragments Secreted by Extracellular Vesicles in Hypopharyngeal Carcinoma

Xi J, Zeng Z, Li X, Zhang X, Xu J

OncoTargets and Therapy 2021, 14:4189-4199

Published Date: 14 July 2021

The Emerging Role of Circ-SHPRH in Cancer

Ju X, Tang Y, Qu R, Hao S

OncoTargets and Therapy 2021, 14:4177-4188

Published Date: 13 July 2021

Key Role of MCUR1 in Malignant Progression of Breast Cancer

Gao P, Peng T, Lin S, Zhi W, Cao C, Wu P, Xi L, Wu P, Yang Q, Ding W

OncoTargets and Therapy 2021, 14:4163-4175

Published Date: 13 July 2021

Recent Advances in Systemic Treatments for HER-2 Positive Advanced Gastric Cancer

Kahraman S, Yalcin S

OncoTargets and Therapy 2021, 14:4149-4162

Published Date: 13 July 2021

FSTL3 is a Prognostic Biomarker in Gastric Cancer and is Correlated with M2 Macrophage Infiltration

Liu YJ, Li JP, Zhang Y, Nie MJ, Zhang YH, Liu SL, Zou X

OncoTargets and Therapy 2021, 14:4099-4117

Published Date: 6 July 2021

Chidamide-Induced Accumulation of Reactive Oxygen Species Increases Lenalidomide Sensitivity Against Multiple Myeloma Cells

Jiang D, Zhang K, Zhu Y, Zhu Y, Zou L, Hu J, Cui Y, Zhou W, Chen F, He Y

OncoTargets and Therapy 2021, 14:4061-4075

Published Date: 6 July 2021

A Novel Biological Activity of the STAT3 Inhibitor Stattic in Inhibiting Glutathione Reductase and Suppressing the Tumorigenicity of Human Cervical Cancer Cells via a ROS-Dependent Pathway

Xia Y, Wang G, Jiang M, Liu X, Zhao Y, Song Y, Jiang B, Zhu D, Hu L, Zhang Z, Cao T, Wang JM, Hu J

OncoTargets and Therapy 2021, 14:4047-4060

Published Date: 5 July 2021

Expression and Clinical Value of LncRNA GAPLINC in Esophageal Squamous Cell Carcinoma

Wang P, Yang S, Dai S, Ni Q, Liu H, Yu L, Lu K, Han G, Huang J

OncoTargets and Therapy 2021, 14:4039-4045

Published Date: 5 July 2021

Anti-CD22 CAR-T Cell Therapy as a Salvage Treatment in B Cell Malignancies Refractory or Relapsed After Anti-CD19 CAR-T therapy

Zhu H, Deng H, Mu J, Lyu C, Jiang Y, Deng Q

OncoTargets and Therapy 2021, 14:4023-4037

Published Date: 2 July 2021

Circular RNAs Regulate Glucose Metabolism in Cancer Cells

Ji X, Sun W, Lv C, Huang J, Zhang H

OncoTargets and Therapy 2021, 14:4005-4021

Published Date: 2 July 2021

Demographic Characteristics and Treatment Patterns Among Patients Receiving Palbociclib for HR+/HER2− Advanced Breast Cancer: A Nationwide Real-World Experience

Boér K, Rubovszky G, Rokszin G, Abonyi-Tóth Z, Földesi C, Dank M

OncoTargets and Therapy 2021, 14:3971-3981

Published Date: 1 July 2021

The Association Between Radioiodine Refractory in Papillary Thyroid Carcinoma, Sodium/Iodide Symporter Expression, and BRAFV600E Mutation

Anekpuritanang T, Uataya M, Claimon A, Laokulrath N, Pongsapich W, Pithuksurachai P

OncoTargets and Therapy 2021, 14:3959-3969

Published Date: 29 June 2021

Durable Response to Crizotinib in a Patient with Pulmonary Adenocarcinoma Harboring MET Intron 14 Mutation: A Case Report

Leyrat B, Durando X, Veyssiere H, Bernadach M

OncoTargets and Therapy 2021, 14:3949-3958

Published Date: 29 June 2021

Nuclear Factor-Kappa B1 Inhibits Early Apoptosis of Glioma Cells by Promoting the Expression of Bcl-2 [Retraction]

Yang TQ, Chen M, Wang YQ, Xu W, Han Y, Xu J, Xiang YJ, Yuan B, Wang HZ, Zhou YX

OncoTargets and Therapy 2021, 14:3943-3944

Published Date: 29 June 2021

Fatty Acid–Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway

Wu Z, Jeong JH, Ren C, Yang L, Ding L, Li F, Jiang D, Zhu Y, Lu J

OncoTargets and Therapy 2021, 14:3929-3942

Published Date: 29 June 2021

PD-L1 Expressing Recurrent Clear Cell Carcinoma of the Vulva with Durable Partial Response to Pembrolizumab: A Case Report

Sachdeva M, Ngoi NY, Lim D, Poon ML, Thian YL, Lim YW, Lim SE, Tong P, Lum JH, Ng J, Ilancheran A, Domingo EJ, Low JJ, Tan DSP

OncoTargets and Therapy 2021, 14:3921-3928

Published Date: 29 June 2021

Remarkable Response to Olaparib in a Patient with Combined Hepatocellular-Cholangiocarcinoma Harboring a Biallelic BRCA2 Mutation

Su YL, Ng CT, Jan YH, Hsieh YL, Wu CL, Tan KT

OncoTargets and Therapy 2021, 14:3895-3901

Published Date: 29 June 2021

Complete Response of Hepatocellular Carcinoma with Macroscopic Vascular Invasion and Pulmonary Metastasis to the Combination of Drug-Eluting Beads Transarterial Chemoembolization and Huaier Granule: A Case Report

Zhou TY, Tao GF, Chen SQ, Wang HL, Zhang YL, Zhou GH, Nie CH, Zhu TY, Wang BQ, Yu ZN, Jing L, Chen F, Sun JH

OncoTargets and Therapy 2021, 14:3873-3880

Published Date: 23 June 2021

Celastrol Modulates Multiple Signaling Pathways to Inhibit Proliferation of Pancreatic Cancer via DDIT3 and ATF3 Up-Regulation and RRM2 and MCM4 Down-Regulation

Youns M, Askoura M, Abbas HA, Attia GH, Khayyat AN, Goda RM, Almalki AJ, Khafagy ES, Hegazy WAH

OncoTargets and Therapy 2021, 14:3849-3860

Published Date: 23 June 2021

Expression Profiles of Circular RNAs in Human Papillary Thyroid Carcinoma Based on RNA Deep Sequencing

Lv C, Sun W, Huang J, Qin Y, Ji X, Zhang H

OncoTargets and Therapy 2021, 14:3821-3832

Published Date: 21 June 2021

Identification of Phospho-Tyrosine Targets as a Strategy for the Treatment of Esophageal Adenocarcinoma Cells

Lee J, Chen R, Mohanakumar T, Bremner R, Mittal S, Fleming TP

OncoTargets and Therapy 2021, 14:3813-3820

Published Date: 21 June 2021

A New Treatment Strategy for Early T‐Cell Precursor Acute Lymphoblastic Leukemia: A Case Report and Literature Review

Mao J, Xue L, Wang H, Zhu Y, Wang J, Zhao L

OncoTargets and Therapy 2021, 14:3795-3802

Published Date: 18 June 2021

Epigenetic Mechanism of Enrichment of A549 Lung Cancer Stem Cells with 5-Fu

Cao F, Shi M, Yu B, Cheng X, Li X, Jia X

OncoTargets and Therapy 2021, 14:3783-3794

Published Date: 18 June 2021

Progesterone Receptor Together with PKCα Expression as Prognostic Factors for Astrocytomas Malignancy

Arcos-Montoya D, Wegman-Ostrosky T, Mejía-Pérez S, De la Fuente-Granada M, Camacho-Arroyo I, García-Carrancá A, Velasco-Velázquez MA, Manjarrez-Marmolejo J, González-Arenas A

OncoTargets and Therapy 2021, 14:3757-3768

Published Date: 16 June 2021

A Novel KIF5B-EGFR Fusion Variant in Non-Small-Cell Lung Cancer and Response to Afatinib: A Case Report

Wang X, Huang L, Cai J, Liu A

OncoTargets and Therapy 2021, 14:3739-3744

Published Date: 14 June 2021

miR-593-3p Promotes Proliferation and Invasion in Prostate Cancer Cells by Targeting ADIPOR1

Huang Q, Peng L, Sun Y, Huang J, Han T, Li Y, Peng H

OncoTargets and Therapy 2021, 14:3729-3737

Published Date: 14 June 2021

G9a Regulates Cell Sensitivity to Radiotherapy via Histone H3 Lysine 9 Trimethylation and CCDC8 in Lung Cancer

Li Y, Chen Z, Cao K, Zhang L, Ma Y, Yu S, Jin H, Liu X, Li W

OncoTargets and Therapy 2021, 14:3721-3728

Published Date: 10 June 2021

Current Perspectives and Novel Strategies of NRAS-Mutant Melanoma

Garcia-Alvarez A, Ortiz C, Muñoz-Couselo E

OncoTargets and Therapy 2021, 14:3709-3719

Published Date: 9 June 2021

miR-210-3p Promotes Lung Cancer Development and Progression by Modulating USF1 and PCGF3

Chen Q, Zhang H, Zhang J, Shen L, Yang J, Wang Y, Ma J, Zhuan B

OncoTargets and Therapy 2021, 14:3687-3700

Published Date: 9 June 2021

Construction and Analysis of a circRNA-Mediated ceRNA Network in Lung Adenocarcinoma

Wang Z, Pei H, Liang H, Zhang Q, Wei L, Shi D, Chen Y, Zhang J

OncoTargets and Therapy 2021, 14:3659-3669

Published Date: 8 June 2021

miR-183-5p Promotes HCC Migration/Invasion via Increasing Aerobic Glycolysis

Niu Y, Liu F, Wang X, Chang Y, Song Y, Chu H, Bao S, Chen C

OncoTargets and Therapy 2021, 14:3649-3658

Published Date: 4 June 2021

miR-340 Promotes Retinoblastoma Cell Proliferation, Migration and Invasion Through Targeting WIF1

Li K, Han F, Wu Y, Wang X

OncoTargets and Therapy 2021, 14:3635-3648

Published Date: 4 June 2021

Identification of Ten Mitosis Genes Associated with Tamoxifen Resistance in Breast Cancer

Sun X, Ding S, Lu S, Wang Z, Chen X, Shen K

OncoTargets and Therapy 2021, 14:3611-3624

Published Date: 4 June 2021

miR-622 Suppresses Tumor Formation by Directly Targeting VEGFA in Papillary Thyroid Carcinoma [Retraction]

Wang R, Ma Q, Ji L, Yao Y, Ma M, Wen Q

OncoTargets and Therapy 2021, 14:3597-3598

Published Date: 3 June 2021

ITGA2 Overexpression Promotes Esophageal Squamous Cell Carcinoma Aggression via FAK/AKT Signaling Pathway

Huang W, Zhu J, Shi H, Wu Q, Zhang C

OncoTargets and Therapy 2021, 14:3583-3596

Published Date: 3 June 2021

Targeted-Gene Sequencing and Bioinformatics Analysis of Patients with Pancreatic Mucoepidermoid Carcinoma: A Case Report and Literature Review

Chen Z, Zhang L, Huang J, Ding C, Zhang T, Wan D, Xue L

OncoTargets and Therapy 2021, 14:3567-3581

Published Date: 3 June 2021

LncRNA PVT1 Facilitates Proliferation, Migration and Invasion of NSCLC Cells via miR-551b/FGFR1 Axis

Wang X, Cheng Z, Dai L, Jiang T, Li P, Jia L, Jing X, An L, Liu M, Wu S, Wang Y

OncoTargets and Therapy 2021, 14:3555-3565

Published Date: 2 June 2021

Dysregulation of Zinc Finger Protein 395 Contributes to the Pathogenesis of Chondrosarcoma

Chen C, Zhou H, Liu Z, Ma X

OncoTargets and Therapy 2021, 14:3545-3553

Published Date: 1 June 2021

Near Complete Pathologic Response to PD-1 Inhibitor and Radiotherapy in a Patient with Locally Advanced Pancreatic Ductal Adenocarcinoma

McCarthy PM, Rendo MJ, Uy MD, Adams AM, O'Shea AE, Nelson DW, Fenderson JL, Cebe KM, Krell RW, Clifton GT, Peoples GE, Vreeland TJ

OncoTargets and Therapy 2021, 14:3537-3544

Published Date: 1 June 2021

Comparative Analysis and in vitro Experiments of Signatures and Prognostic Value of Immune Checkpoint Genes in Colorectal Cancer

Ma R, Qu X, Che X, Yang B, Li C, Hou K, Guo T, Xiao J, Liu Y

OncoTargets and Therapy 2021, 14:3517-3534

Published Date: 31 May 2021

Acetone Extract of Cornus officinalis Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling

Xu R, Zeng M, Wu Y, Wang S, Zhang B, Zhang J, Kan Y, Li B, Cao B, Zheng X, Feng W

OncoTargets and Therapy 2021, 14:3487-3501

Published Date: 28 May 2021

Silencing HIPPI Suppresses Tumor Progression in Non-Small-Cell Lung Cancer by Inhibiting DNA Replication

Xie G, Li Y, Jiang Y, Ye X, Tang J, Chen J

OncoTargets and Therapy 2021, 14:3467-3480

Published Date: 27 May 2021

Clinical Significance of the D-Loop Gene Mutation in Mitochondrial DNA in Laryngeal Cancer

Wang L, Cheng HX, Zhou YH, Ma M

OncoTargets and Therapy 2021, 14:3461-3466

Published Date: 26 May 2021

Targeted Sequencing Facilitated Diagnosis of an Uncommon Patient Harboring Both Multiple Primary and Intrapulmonary Metastatic Lung Cancer: A Case Report

Li H, Dong S, Zhang D, Guo Z, Li C, Xiang J, Zou X, Yan L, Sun Y, Li W

OncoTargets and Therapy 2021, 14:3455-3459

Published Date: 26 May 2021

NUSAP1 Accelerates Osteosarcoma Cell Proliferation and Cell Cycle Progression via Upregulating CDC20 and Cyclin A2

Wang H, Liu Z, Wu P, Wang H, Ren W

OncoTargets and Therapy 2021, 14:3443-3454

Published Date: 25 May 2021

Preparation, Biocompatibility and Antitumor Activity of Nanodelivery System Targeting Breast Cancer Base on a Silica Nanoparticle

Liu J, Ren S, Zhang X, Feng Y, Qiu Z, Ma L, Huang J

OncoTargets and Therapy 2021, 14:3429-3442

Published Date: 25 May 2021

Platelets: The Emerging Clinical Diagnostics and Therapy Selection of Cancer Liquid Biopsies

Meng Y, Sun J, Zheng Y, Zhang G, Yu T, Piao H

OncoTargets and Therapy 2021, 14:3417-3428

Published Date: 25 May 2021

Successful Treatment with Ensartinib After Alectinib-induced Hyperbilirubinemia in ALK-Positive NSCLC

Peng L, Xiao K, Cui J, Ye XH, Zhang YC, Mao L, Selvaggi G, Yen J, Stebbing J

OncoTargets and Therapy 2021, 14:3409-3415

Published Date: 25 May 2021

LINC00894 Enhances the Progression of Breast Cancer by Sponging miR-429 to Regulate ZEB1 Expression

Meng D, Shao H, Feng C

OncoTargets and Therapy 2021, 14:3395-3407

Published Date: 25 May 2021

SOX17 Antagonizes the WNT Signaling Pathway and is Epigenetically Inactivated in Clear-Cell Renal Cell Carcinoma

Wang L, Wang Z, Zhu Y, Tan S, Chen X, Yang X

OncoTargets and Therapy 2021, 14:3383-3394

Published Date: 24 May 2021

Efficacy and Safety of Systemic and Locoregional Cisplatin Chronotherapy in Rats with Ovarian Carcinoma

Kireeva G, Gubareva E, Maydin M, Osetnik V, Kruglov S, Panchenko A, Dorofeeva A, Tyndyk M, Fedoros E, Anisimov V

OncoTargets and Therapy 2021, 14:3373-3381

Published Date: 24 May 2021

The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation

Kuang Q, Liang Y, Zhuo Y, Cai Z, Jiang F, Xie J, Zheng Y, Zhong W

OncoTargets and Therapy 2021, 14:3353-3366

Published Date: 24 May 2021

Functions and Targets of miR-335 in Cancer

Ye L, Wang F, Wu H, Yang H, Yang Y, Ma Y, Xue A, Zhu J, Chen M, Wang J, Zhang QA

OncoTargets and Therapy 2021, 14:3335-3349

Published Date: 20 May 2021

Sevoflurane Suppresses Colon Cancer Cell Malignancy by Regulating circ-PI4KA

Sun S, Wang P, Ren L, Wang H, Zhan Y, Shan S

OncoTargets and Therapy 2021, 14:3319-3333

Published Date: 20 May 2021

High Expression of Cyclin D1 is an Independent Marker for Favorable Prognosis in Middle Eastern Breast Cancer

Siraj AK, Parvathareddy SK, Annaiyappanaidu P, Ahmed SO, Siraj N, Tulbah A, Al-Dayel F, Ajarim D, Al-Kuraya KS

OncoTargets and Therapy 2021, 14:3309-3318

Published Date: 19 May 2021

MiR-144 Suppresses Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Targeting SMAD4 [Retraction]

Yu M, Lin Y, Zhou Y, Jin H, Hou B, Wu Z, Li Z, Jian Z, Sun J

OncoTargets and Therapy 2021, 14:3295-3296

Published Date: 19 May 2021

Circular RNA circWDR27 Promotes Papillary Thyroid Cancer Progression by Regulating miR-215-5p/TRIM44 Axis

Wang W, Huang C, Luo P, Yao J, Li J, Wang W, Liu F

OncoTargets and Therapy 2021, 14:3281-3293

Published Date: 19 May 2021

Artificial Intelligence Based on Blood Biomarkers Including CTCs Predicts Outcomes in Epithelial Ovarian Cancer: A Prospective Study

Ma J, Yang J, Jin Y, Cheng S, Huang S, Zhang N, Wang Y

OncoTargets and Therapy 2021, 14:3267-3280

Published Date: 18 May 2021

Comprehensive Analysis of the Relationship Between Metabolic Reprogramming and Immune Function in Prostate Cancer

Xie W, Guo H, Zhang J, Hu L, Wu Y, Wang X

OncoTargets and Therapy 2021, 14:3251-3266

Published Date: 18 May 2021

MicroRNA-29b-3p Inhibits the Migration and Invasion of Gastric Cancer Cells by Regulating the Autophagy-Associated Protein MAZ

Zhao X, Ye N, Feng X, Ju H, Liu R, Lu W

OncoTargets and Therapy 2021, 14:3239-3249

Published Date: 18 May 2021

LncRNA ST8SIA6-AS1 Promotes Cholangiocarcinoma Progression by Suppressing the miR-145-5p/MAL2 Axis

He J, Yan H, Wei S, Chen G

OncoTargets and Therapy 2021, 14:3209-3223

Published Date: 17 May 2021

Urolithin A Inhibits Epithelial–Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway

Cheng F, Dou J, Zhang Y, Wang X, Wei H, Zhang Z, Cao Y, Wu Z

OncoTargets and Therapy 2021, 14:3199-3208

Published Date: 17 May 2021

Regional Brain Glucose Metabolism and Its Prognostic Value in Pretreatment Extranodal Natural Killer/T-Cell Lymphoma Patients

Zhou Z, Guo Z, Hu Q, Ding W, Ding C, Tang L

OncoTargets and Therapy 2021, 14:3179-3191

Published Date: 14 May 2021

MiR-502-3P Suppresses Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Targeting SET [Retraction]

Jin H, Yu M, Lin Y, Hou B, Wu Z, Li Z, Sun J

OncoTargets and Therapy 2021, 14:3177-3178

Published Date: 18 May 2021

Diagnosis and Individualized Treatment of Secondary Central Nervous System Lymphoma: A Case Report

Li Q, Liu W, Li K, Tian Y, Li H

OncoTargets and Therapy 2021, 14:3167-3175

Published Date: 13 May 2021

Epigenetic Study of Esophageal Carcinoma Based on Methylation, Gene Integration and Weighted Correlation Network Analysis

Xu Y, Wang N, Liu R, Lv H, Li Z, Zhang F, Gai C, Tian Z

OncoTargets and Therapy 2021, 14:3133-3149

Published Date: 13 May 2021

Identification of the EMT-Related Genes Signature for Predicting Occurrence and Progression in Thyroid Cancer

Li Q, Jiang S, Feng T, Zhu T, Qian B

OncoTargets and Therapy 2021, 14:3119-3131

Published Date: 12 May 2021

MiR-17 and miR-93 Promote Tumor Progression by Targeting p21 in Patients with Chordoma

Dong W, Li J, Dong X, Shi W, Zhang Y, Liu Y

OncoTargets and Therapy 2021, 14:3109-3118

Published Date: 12 May 2021

Long Noncoding RNA CCDC26 Promotes Thyroid Cancer Malignant Progression via miR-422a/EZH2/Sirt6 Axis

Ma X, Li Y, Song Y, Xu G

OncoTargets and Therapy 2021, 14:3083-3094

Published Date: 11 May 2021

Significant Benefits of Afatinib and Apatinib in a Refractory Advanced NSCLC Patient Resistant to Osimertinib: A Case Report

Zhao Y, Chen Y, Huang H, Li X, Shao L, Ding H

OncoTargets and Therapy 2021, 14:3063-3067

Published Date: 7 May 2021

IFNγ/PD-L1 Signaling Improves the Responsiveness of Anti-PD-1 Therapy in Colorectal Cancer: An in vitro Study

Yuan W, Deng D, Li H, Hu X, Shang X, Hou X, Jiang H, He H

OncoTargets and Therapy 2021, 14:3051-3062

Published Date: 7 May 2021

A Phase I Trial of the MET/ALK/ROS1 Inhibitor Crizotinib Combined with the VEGF Inhibitor Pazopanib in Patients with Advanced Solid Malignancies

Piha-Paul SA, Dumbrava EE, Nair BC, Xiong W, Xu L, Mostorino R, Subbiah V, Tannir N, Fu S, Naing A, Janku F, Karp DD, Patel S, Daw NC, Hong D, Meric-Bernstam F, Zinner R

OncoTargets and Therapy 2021, 14:3037-3049

Published Date: 7 May 2021

Emerging Mechanisms and Treatment Progress on Liver Metastasis of Colorectal Cancer

Zheng W, Wu F, Fu K, Sun G, Sun G, Li X, Jiang W, Cao H, Wang H, Tang W

OncoTargets and Therapy 2021, 14:3013-3036

Published Date: 6 May 2021

A Case of Phyllodes Tumor of the Breast with Mixed Liposarcoma: Case Report and Literature Review

Tu He Ta Mi Shi ME, Wang N, Yao Q, Dong SS, Feng X, Zhao J, Zou H, Pang LJ, Qi Y

OncoTargets and Therapy 2021, 14:3003-3011

Published Date: 6 May 2021

Increased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression

Wang J, Jiang YH, Yang PY, Liu F

OncoTargets and Therapy 2021, 14:2991-3002

Published Date: 5 May 2021

High Expression of SLC41A3 Correlates with Poor Prognosis in Hepatocellular Carcinoma

Li Q, Xiong DL, Wang H, Jin WL, Ma YY, Fan XM

OncoTargets and Therapy 2021, 14:2975-2988

Published Date: 5 May 2021

Treatment Strategies for Metastatic Castration-Sensitive Prostate Cancer: From “All-Comers” to “Personalized” Approach

Harada K, Shiota M, Minato A, Matsumoto M, Tomisaki I, Fujisawa M, Fujimoto N

OncoTargets and Therapy 2021, 14:2967-2974

Published Date: 5 May 2021

Tumor Mutation Burden and Differentially Mutated Genes Among Immune Phenotypes in Patients with Lung Adenocarcinoma

Wang H, Chen S, Meng D, Wu C, Zhu J, Jiang M, Ning J, Wu S, Wu L, Li J, Chen B, Zhao S, Li W, Yu J, Fang Q, Zhu J, Zhao W, He Y, Zhou C

OncoTargets and Therapy 2021, 14:2953-2965

Published Date: 4 May 2021

Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma

Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B

OncoTargets and Therapy 2021, 14:2941-2952

Published Date: 4 May 2021

Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma

Gu W, Chen P, Ren P, Wang Y, Li X, Gong M

OncoTargets and Therapy 2021, 14:2917-2927

Published Date: 30 April 2021

Alectinib for Miliary Lung Metastasis in ALK-Positive Lung Adenocarcinoma

Satoh H, Okuma Y, Kashima J, Konnno-Yamamoto A, Yatabe Y, Ohe Y

OncoTargets and Therapy 2021, 14:2911-2915

Published Date: 30 April 2021

Exploration of the Associations of lncRNA Expression Patterns with Tumor Mutation Burden and Prognosis in Colon Cancer

Ding C, Shan Z, Li M, Xia Y, Jin Z

OncoTargets and Therapy 2021, 14:2893-2909

Published Date: 29 April 2021

MiR-140-3p Impedes Gastric Cancer Progression and Metastasis by Regulating BCL2/BECN1-Mediated Autophagy

Chen J, Cai S, Gu T, Song F, Xue Y, Sun D

OncoTargets and Therapy 2021, 14:2879-2892

Published Date: 29 April 2021

LncRNA EGOT/miR-211-5p Affected Radiosensitivity of Rectal Cancer by Competitively Regulating ErbB4

Li C, Liu H, Wei R, Liu Z, Chen H, Guan X, Zhao Z, Wang X, Jiang Z

OncoTargets and Therapy 2021, 14:2867-2878

Published Date: 28 April 2021

TCEB3 is Regulated by Circ-0000212/miR-140-3p Axis to Promote the Progression of Cervical Cancer

Wang Y, Miao C, Gao X

OncoTargets and Therapy 2021, 14:2853-2865

Published Date: 28 April 2021

Combination of Osimertinib and Anlotinib May Overcome the Resistance Mediated by in cis EGFR T790M-C797S in NSCLC: A Case Report

Zhou R, Song L, Zhang W, Shao L, Li X, Li X

OncoTargets and Therapy 2021, 14:2847-2851

Published Date: 28 April 2021

A Novel Circular RNA circCSPP1 Promotes Liver Cancer Progression by Sponging miR-1182

Jia N, Song Z, Chen B, Cheng J, Zhou W

OncoTargets and Therapy 2021, 14:2829-2838

Published Date: 23 April 2021

EGFR (p. G719A+L747V)/EML4-ALK Co-alterations in Lung Adenocarcinoma with Leptomeningeal Metastasis Responding to Afatinib Treatment: A Case Report

Lu Z, Wang X, Luo Y, Wei J, Zeng Z, Xiong Q, Cai J, Liu A

OncoTargets and Therapy 2021, 14:2823-2828

Published Date: 23 April 2021

Olaparib Treatment in a Patient with Advanced Gallbladder Cancer Harboring BRCA1 Mutation

Li X, Gao L, Qiu M, Cao D

OncoTargets and Therapy 2021, 14:2815-2819

Published Date: 22 April 2021

Downregulation of Chemokine CCL20 Involved in Myeloma Cells Resistant to Elotuzumab and Lenalidomide

Wang H, Shi H, He X, Liao A

OncoTargets and Therapy 2021, 14:2789-2795

Published Date: 21 April 2021

A Concise Review: The Role of Stem Cells in Cancer Progression and Therapy

Hayat H, Hayat H, Dwan BF, Gudi M, Bishop JO, Wang P

OncoTargets and Therapy 2021, 14:2761-2772

Published Date: 20 April 2021

lncRNA GSEC Promotes the Progression of Triple Negative Breast Cancer (TNBC) by Targeting the miR-202-5p/AXL Axis

Zhang J, Du C, Zhang L, Wang Y, Zhang Y, Li J

OncoTargets and Therapy 2021, 14:2747-2759

Published Date: 20 April 2021

Exosomes Derived from Pancreatic Cancer Cells Induce Osteoclast Differentiation Through the miR125a-5p/TNFRSF1B Pathway

Zhou Y, Zhu Y, Dong X, Cao G, Li Y, Fan Y, Chen Q, Cai H, Wu Y

OncoTargets and Therapy 2021, 14:2727-2739

Published Date: 19 April 2021

LINC00184 Promotes Ovarian Cancer Cells Proliferation and Cisplatin Resistance by Elevating CNTN1 Expression via Sponging miR-1305

Han Y, You J, Han Y, Liu Y, Huang M, Lu X, Chen J, Zheng Y

OncoTargets and Therapy 2021, 14:2711-2726

Published Date: 19 April 2021

Expression and Prognosis of Sperm-Associated Antigen 1 in Human Breast Cancer

Lin S, Lv Y, Zheng L, Mao G, Peng F

OncoTargets and Therapy 2021, 14:2689-2698

Published Date: 16 April 2021

3D Culture of Circulating Tumor Cells for Evaluating Early Recurrence and Metastasis in Patients with Hepatocellular Carcinoma

Hu CL, Zhang YJ, Zhang XF, Fei X, Zhang H, Li CG, Sun B

OncoTargets and Therapy 2021, 14:2673-2688

Published Date: 16 April 2021

GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2+ Macrophage Infiltration in Mice

Li M, Huang T, Li X, Shi Z, Sheng Y, Hu M, Song K

OncoTargets and Therapy 2021, 14:2661-2672

Published Date: 15 April 2021

Desmoplastic Melanoma: A Clinicopathological Analysis of Three Cases in the Chinese Population

Fan Y, Xu M, Liang Y, Wu N, Wang F, Du Q, Bai Y, Liu Y

OncoTargets and Therapy 2021, 14:2651-2660

Published Date: 15 April 2021

Bioinformatics Analysis of the SIRT Family Members and Assessment of Their Potential Clinical Value

Liu M, Yu J, Jin H, Wang S, Ding J, Xing H, He S, Zeng Y

OncoTargets and Therapy 2021, 14:2635-2649

Published Date: 15 April 2021

Role of G Protein-Coupled Estrogen Receptor in Digestive System Carcinomas: A Minireview

Qiu YA, Xiong J, Yu T

OncoTargets and Therapy 2021, 14:2611-2622

Published Date: 14 April 2021

A Novel Transcription Factor-Based Prognostic Signature in Endometrial Cancer: Establishment and Validation

Yang X, Cheng Y, Li X, Zhou J, Dong Y, Shen B, Zhao L, Wang J

OncoTargets and Therapy 2021, 14:2579-2598

Published Date: 13 April 2021

Dihydroartemisinin as a Sensitizing Agent in Cancer Therapies

Li Q, Ma Q, Cheng J, Zhou X, Pu W, Zhong X, Guo X

OncoTargets and Therapy 2021, 14:2563-2573

Published Date: 13 April 2021

MicroRNA-302s Might Regulate ARL4C-Mediated Gastric Cancer Progression via p53 Signaling: Bioinformatics Analysis and Experiments Validation

Xie N, Pan Y, Wu J, Bai Y, Xiao C, Gao X, Wang J, Liu N

OncoTargets and Therapy 2021, 14:2541-2553

Published Date: 13 April 2021

Consequences of Mutations and Abnormal Expression of SMAD4 in Tumors and T Cells

Wan R, Feng J, Tang L

OncoTargets and Therapy 2021, 14:2531-2540

Published Date: 13 April 2021

GDC-0326 Enhances the Effects of 5-Fu in Colorectal Cancer Cells by Inducing Necroptotic Death

Zhang Z, Ju F, Chen F, Wu H, Chen J, Zhong J, Shao L, Zheng S, Wang L, Xue M

OncoTargets and Therapy 2021, 14:2519-2530

Published Date: 13 April 2021

Calycosin Induces Gastric Cancer Cell Apoptosis via the ROS-Mediated MAPK/STAT3/NF-κB Pathway

Zhang Y, Zhang JQ, Zhang T, Xue H, Zuo WB, Li YN, Zhao Y, Sun G, Fu ZR, Zhang Q, Zhao X, Teng Y, Wang AQ, Li JZ, Wang Y, Jin CH

OncoTargets and Therapy 2021, 14:2505-2517

Published Date: 12 April 2021

Hodgkin Lymphoma as a Secondary Neoplasm During Therapy for Chronic Myeloid Leukaemia: Case Report and Review of the Literature

Paczkowska E, Janowski M, Karpińska K, Ryłów M, Zdziarska B, Poncyljusz W, Machaliński B

OncoTargets and Therapy 2021, 14:2497-2503

Published Date: 12 April 2021

Actin-Like Protein 8 Promotes the Progression of Triple-Negative Breast Cancer via Activating PI3K/AKT/mTOR Pathway

Fan S, Yan S, Yang Y, Shang J, Hao M

OncoTargets and Therapy 2021, 14:2463-2473

Published Date: 12 April 2021

Integrated Profiling Identifies CCNA2 as a Potential Biomarker of Immunotherapy in Breast Cancer

Wang Y, Zhong Q, Li Z, Lin Z, Chen H, Wang P

OncoTargets and Therapy 2021, 14:2433-2448

Published Date: 9 April 2021

Development and Analytical Validation of a Targeted Next-Generation Sequencing Panel to Detect Actionable Mutations for Targeted Therapy

Wang D, Ma K, Deng W, Li J, Xiang S, Zhang Y, Fu Y, Dai H, Huang B

OncoTargets and Therapy 2021, 14:2423-2431

Published Date: 7 April 2021

Rapid Disease Progression in a Patient with Advanced NSCLC Harboring a Germline MET Exon 14 Skipping Mutation: A Case Report

Jiao Y, Fang C, Yang Y, Shao L, Huang Y, Sun Q, Dong Y

OncoTargets and Therapy 2021, 14:2417-2421

Published Date: 7 April 2021

Advances in Understanding the LncRNA-Mediated Regulation of the Hippo Pathway in Cancer

Wang M, Xu T, Feng W, Liu J, Wang Z

OncoTargets and Therapy 2021, 14:2397-2415

Published Date: 7 April 2021

Tip of the Iceberg: Roles of CircRNAs in Cancer Glycolysis

Li T, Xian H, Dai L, Tang Y, Liang X

OncoTargets and Therapy 2021, 14:2379-2395

Published Date: 7 April 2021

Construction of miRNA-mRNA Regulatory Network and Prognostic Signature in Endometrial Cancer

Sun R, Liu J, Nie S, Li S, Yang J, Jiang Y, Cheng W

OncoTargets and Therapy 2021, 14:2363-2378

Published Date: 6 April 2021

XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer

Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T

OncoTargets and Therapy 2021, 14:2339-2348

Published Date: 6 April 2021

Serum Exosomal miRNA Might Be a Novel Liquid Biopsy to Identify Leptomeningeal Metastasis in Non-Small Cell Lung Cancer

Xu Q, Ye L, Huang L, Zhou L, Chen X, Ye M, Wu G, Zhan P, Lv T, Song Y

OncoTargets and Therapy 2021, 14:2327-2335

Published Date: 1 April 2021

miR-944 Suppresses EGF-Induced EMT in Colorectal Cancer Cells by Directly Targeting GATA6

Tang J, Gao W, Liu G, Sheng W, Zhou J, Dong Q, Dong M

OncoTargets and Therapy 2021, 14:2311-2325

Published Date: 31 March 2021

Identification of Metabolic-Associated Genes for the Prediction of Colon and Rectal Adenocarcinoma

Cui Y, Han B, Zhang H, Liu H, Zhang F, Niu R

OncoTargets and Therapy 2021, 14:2259-2277

Published Date: 31 March 2021

Bronchiolar Adenoma Transforming to Invasive Mucinous Adenocarcinoma: A Case Report

Han X, Hao J, Ding S, Wang EH, Wang L

OncoTargets and Therapy 2021, 14:2241-2246

Published Date: 30 March 2021

MicroRNA-769-5p Promotes the Growth of Glioma Cells by Targeting Lysine Methyltransferase 2A [Corrigendum]

Chang M, Yan P, Zhang B, Zhang G, Wang J, Ge H, Han N, Du C, Shi W, Tian Y

OncoTargets and Therapy 2021, 14:2237-2238

Published Date: 29 March 2021

Long Non-Coding RNA LINC00313 Accelerates Cervical Carcinoma Progression by miR-4677-3p/CDK6 Axis

Zhai Y, Liu Y, Wang Z, Wang W, Zhou J, Lu J

OncoTargets and Therapy 2021, 14:2213-2226

Published Date: 29 March 2021

A Review of Chimeric Antigen Receptor T-Cell Therapy for Myeloma and Lymphoma

Atrash S, Moyo TK

OncoTargets and Therapy 2021, 14:2185-2201

Published Date: 26 March 2021

Upregulated MicroRNA-483-3p is an Early Event in Pancreatic Ductal Adenocarcinoma (PDAC) and as a Powerful Liquid Biopsy Biomarker in PDAC

Shao H, Zhang Y, Yan J, Ban X, Fan X, Chang X, Lu Z, Wu Y, Zong L, Mo S, Yu S, Chen J

OncoTargets and Therapy 2021, 14:2163-2175

Published Date: 25 March 2021

CD8+CD39+ T Cells Mediate Anti-Tumor Cytotoxicity in Bladder Cancer

Zhu W, Zhao Z, Feng B, Yu W, Li J, Guo H, Yang R

OncoTargets and Therapy 2021, 14:2149-2161

Published Date: 25 March 2021

Primary Tumor Radiotherapy During EGFR-TKI Disease Control Improves Survival of Treatment Naïve Advanced EGFR-Mutant Lung Adenocarcinoma Patients

Hsu KH, Huang JW, Tseng JS, Chen KW, Weng YC, Yu SL, Yang TY, Huang YH, Chen JJW, Chen KC, Chang GC

OncoTargets and Therapy 2021, 14:2139-2148

Published Date: 25 March 2021

Identification of Novel Alectinib-Resistant ALK Mutation G1202K with Sensitization to Lorlatinib: A Case Report and in silico Structural Modelling

Yang P, Cao R, Bao H, Wu X, Yang L, Zhu D, Zhang L, Peng L, Cai Y, Zhang W, Shao Y

OncoTargets and Therapy 2021, 14:2131-2138

Published Date: 25 March 2021

Global Characterization of Immune Infiltration in Clear Cell Renal Cell Carcinoma

Zheng Y, Wen Y, Cao H, Gu Y, Yan L, Wang Y, Wang L, Zhang L, Shao F

OncoTargets and Therapy 2021, 14:2085-2100

Published Date: 22 March 2021

Evaluation of Cervical High-Grade Squamous Intraepithelial Lesions-Correlated Markers as Triage Strategy for Colposcopy After Co-Testing

Huo X, Sun H, Cao D, Yang J, Peng P, Kong L, Chen F, Shen K, Li S

OncoTargets and Therapy 2021, 14:2075-2084

Published Date: 19 March 2021

Helicobacter pylori Regulates the Apoptosis of Human Megakaryocyte Cells via NF-κB/IL-17 Signaling

Lei H, Ma Y, Tan J, Liu Q

OncoTargets and Therapy 2021, 14:2065-2074

Published Date: 19 March 2021

Role and Therapeutic Potential of Melatonin in Various Type of Cancers

Gurunathan S, Qasim M, Kang MH, Kim JH

OncoTargets and Therapy 2021, 14:2019-2052

Published Date: 18 March 2021

DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer

Deng Z, Xiao M, Du D, Luo N, Liu D, Liu T, Lian D, Peng J

OncoTargets and Therapy 2021, 14:2003-2017

Published Date: 18 March 2021

Apatinib Combined with Irinotecan in the Treatment of Advanced Small-Cell Esophageal Carcinoma: A Case Report

Guo L, Zou X, Gu Y, Yi L, Zhao J, Wu G

OncoTargets and Therapy 2021, 14:1989-1995

Published Date: 18 March 2021

Organ-Specific Tumor Response to Pembrolizumab in Advanced Urothelial Carcinoma After Platinum-Based Chemotherapy

Furubayashi N, Negishi T, Sakamoto N, Shimokawa H, Morokuma F, Song Y, Hori Y, Tomoda T, Tokuda N, Seki N, Kuroiwa K, Nakamura M

OncoTargets and Therapy 2021, 14:1981-1988

Published Date: 18 March 2021

Potential Role of Musashi-2 RNA-Binding Protein in Cancer EMT

Sun J, Sheng W, Ma Y, Dong M

OncoTargets and Therapy 2021, 14:1969-1980

Published Date: 17 March 2021

Anti–PD-1 Monotherapy for Advanced NSCLC Patients with Older Age or Those with Poor Performance Status

Matsubara T, Seto T, Takamori S, Fujishita T, Toyozawa R, Ito K, Yamaguchi M, Okamoto T

OncoTargets and Therapy 2021, 14:1961-1968

Published Date: 17 March 2021

Lack of Synergy Between β-Agonist Treatment and a Blockage of Sarcoplasmic Calcium Flow in a Rat Cancer Cachexia Model

Busquets S, Castillejo M, Jové Q, Jude B, Mejías P, López-Soriano FJ, Argilés JM

OncoTargets and Therapy 2021, 14:1953-1959

Published Date: 17 March 2021

Assessment of the Circulating Tumor Cells and Microsatellite Instability in Colorectal Cancer Patients: Prognostic and Diagnostic Value

Alsayed A, Salem SE, El Serafi MM, Abdellateif MS, Zekri ARN, Mohanad M, Bahnassy AA

OncoTargets and Therapy 2021, 14:1937-1951

Published Date: 16 March 2021

Anti-Lung Cancer Targets of Radix Paeoniae Rubra and Biological Molecular Mechanism: Network Pharmacological Analyses and Experimental Validation

Ma Y, Li G, Yu M, Cao K, Li Q, Sun X, Yang G, Wang X

OncoTargets and Therapy 2021, 14:1925-1936

Published Date: 16 March 2021

Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis

Jin Y, Kang Y, Peng X, Yang L, Li Q, Mei Q, Chen X, Hu G, Tang Y, Yuan X

OncoTargets and Therapy 2021, 14:1911-1922

Published Date: 16 March 2021

Single-Cell Sequencing, an Advanced Technology in Lung Cancer Research

Wang H, Meng D, Guo H, Sun C, Chen P, Jiang M, Xu Y, Yu J, Fang Q, Zhu J, Zhao W, Wu S, Zhao S, Li W, Chen B, Wang L, He Y

OncoTargets and Therapy 2021, 14:1895-1909

Published Date: 16 March 2021

Current Progress and Future Perspectives of Immune Checkpoint Inhibitors in Biliary Tract Cancer

Seesaha PK, Wang KX, Wang GQ, Cui TY, Zhao FJ, Pan LL, Li XC, Shu YQ, Chen XF

OncoTargets and Therapy 2021, 14:1873-1882

Published Date: 12 March 2021

ARID4B Knockdown Suppresses PI3K/AKT Signaling and Induces Apoptosis in Human Glioma Cells

Luo SM, Tsai WC, Tsai CK, Chen Y, Hueng DY

OncoTargets and Therapy 2021, 14:1843-1855

Published Date: 10 March 2021

Natural Polyphyllins (I, II, D, VI, VII) Reverses Cancer Through Apoptosis, Autophagy, Mitophagy, Inflammation, and Necroptosis

Ahmad B, Gamallat Y, Khan MF, Din SR, Israr M, Ahmad M, Tahir N, Azam N, Rahman KU, Xin W, Zexu W, Linjie P, Su P, Liang W

OncoTargets and Therapy 2021, 14:1821-1841

Published Date: 10 March 2021

Circ-PITX1 Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1248/CCND2 Axis

Yue Q, Xu Y, Deng X, Wang S, Qiu J, Qian B, Zhang Y

OncoTargets and Therapy 2021, 14:1807-1819

Published Date: 9 March 2021

Current and Emerging Therapeutic Options for Hairy Cell Leukemia Variant

Liu Q, Harris N, Epperla N, Andritsos LA

OncoTargets and Therapy 2021, 14:1797-1805

Published Date: 9 March 2021

P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization

Wang Q, Zhang J, Fang S, Wang J, Han X, Liu F, Jin G

OncoTargets and Therapy 2021, 14:1771-1782

Published Date: 8 March 2021

High Expression of LINC01268 is Positively Associated with Hepatocellular Carcinoma Progression via Regulating MAP3K7

Jin X, Fu WX, Li D, Wang N, Chen J, Zeng Z, Guo J, Liu H, Zhong X, Peng H, Yu X, Sun J, Zhang X, Wang X, Xu B, Lin Y, Liu J, Kutter C, Li Y

OncoTargets and Therapy 2021, 14:1753-1769

Published Date: 8 March 2021

Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma

Huang H, Tan M, Zheng L, Yan G, Li K, Lu D, Cui X, He S, Lei D, Zhu B, Zhao J

OncoTargets and Therapy 2021, 14:1737-1751

Published Date: 5 March 2021

Biological Function of HYOU1 in Tumors and Other Diseases

Rao S, Oyang L, Liang J, Yi P, Han Y, Luo X, Xia L, Lin J, Tan S, Hu J, Wang H, Tang L, Pan Q, Tang Y, Zhou Y, Liao Q

OncoTargets and Therapy 2021, 14:1727-1735

Published Date: 5 March 2021

Early Study of Tumor Abnormal Protein in Gastric Adenocarcinoma

Zhang M, Wang X, Wang Z

OncoTargets and Therapy 2021, 14:1719-1726

Published Date: 5 March 2021

Carbonic Anhydrase XII is a Clinically Significant, Molecular Tumor-Subtype Specific Therapeutic Target in Glioma with the Potential to Combat Invasion of Brain Tumor Cells

Li G, Chen TW, Nickel AC, Muhammad S, Steiger HJ, Tzaridis T, Hänggi D, Zeidler R, Zhang W, Kahlert UD

OncoTargets and Therapy 2021, 14:1707-1718

Published Date: 4 March 2021

Prognostic Value and Biological Functions of RNA Binding Proteins in Stomach Adenocarcinoma

Li J, Zhou W, Wei J, Xiao X, An T, Wu W, He Y

OncoTargets and Therapy 2021, 14:1689-1705

Published Date: 4 March 2021

Targeting the IDO-BCL2A1-Cytochrome c Pathway Promotes Apoptosis in Oral Squamous Cell Carcinoma

Zheng Q, Gan G, Gao X, Luo Q, Chen F

OncoTargets and Therapy 2021, 14:1673-1687

Published Date: 4 March 2021

LncRNA KCNQ1OT1 Promotes Proliferation, Invasion and Metastasis of Prostate Cancer by Regulating miR-211-5p/CHI3L1 Pathway

Hao H, Chen H, Xie L, Liu H, Wang D

OncoTargets and Therapy 2021, 14:1659-1671

Published Date: 3 March 2021

RPN2 Predicts Poor Prognosis and Promotes Bladder Cancer Growth and Metastasis via the PI3K-Akt Pathway

Han C, Chen S, Ma H, Wen X, Wang Z, Xu Y, Jin X, Yu X, Wang M

OncoTargets and Therapy 2021, 14:1643-1657

Published Date: 3 March 2021

High VCAM-1 Predicts Poor Prognosis and is Associated with Chemotherapy Resistance in Nasopharyngeal Carcinoma

Huang Y, Miao H, Xia C, Feng H, Xu S, Liang Z, Wang Y, Zhao C, Qin G, Ou X, Zhao F

OncoTargets and Therapy 2021, 14:1633-1641

Published Date: 2 March 2021

REG4 is a Potential Biomarker for Radiochemotherapy Sensitivity in Colorectal Cancer

Gao L, Wu X, Zhang L, Dai Y, Zhu Z, Zhi Y, Wang K

OncoTargets and Therapy 2021, 14:1605-1611

Published Date: 2 March 2021

An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma

Chen K, Zhu P, Liao Y, Yan L, Feng R, Zhai W

OncoTargets and Therapy 2021, 14:1589-1604

Published Date: 2 March 2021

Clinical Significance and Oncogenic Activity of GRWD1 Overexpression in the Development of Colon Carcinoma

Zhou X, Shang J, Liu X, Zhuang JF, Yang YF, Zhang YY, Guan GX

OncoTargets and Therapy 2021, 14:1565-1580

Published Date: 2 March 2021

MiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway

Yuan J, Zhang Q, Wu S, Yan S, Zhao R, Sun Y, Tian X, Zhou K

OncoTargets and Therapy 2021, 14:1553-1564

Published Date: 2 March 2021

Biological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase

Qiu Z, Deng W, Hong Y, Zhao L, Li M, Guan Y, Su Y, Chen C, Shi Q, Yu J, Wang W

OncoTargets and Therapy 2021, 14:1531-1542

Published Date: 1 March 2021

The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma

Peng X, Sun J, Long Y, Xiao D, Zhou J, Tao Y, Liu S

OncoTargets and Therapy 2021, 14:1517-1529

Published Date: 1 March 2021

FAST1 Predicts Poor Survival of Renal Carcinoma and Promotes Its Progression Through the TGF-β/Smad Pathway

Tian T, Fu X, Hu L, Yang X, Sun P, Sun F

OncoTargets and Therapy 2021, 14:1487-1499

Published Date: 26 February 2021

FLT3-ITD Mutation and FLT3 Ligand Plasma Level Were Not Associated with One-Year Survival of Indonesian Acute Myeloid Leukemia Patients

Rinaldi I, Louisa M, Mulya Sari R, Arwanih E

OncoTargets and Therapy 2021, 14:1479-1486

Published Date: 26 February 2021

A Functional Food Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Inflammatory Colorectal Cancer in Mice

Zhang J, Chen Z, Lu Y, Tu D, Zou F, Lin S, Yu W, Miao M, Shi H

OncoTargets and Therapy 2021, 14:1465-1477

Published Date: 26 February 2021

Small Proline-Rich Protein 2B Facilitates Gastric Adenocarcinoma Proliferation via MDM2-p53/p21 Signaling Pathway

Yao L, Yan J, Cheng F, Gan L, Huang Y, Zheng L, Fang N

OncoTargets and Therapy 2021, 14:1453-1463

Published Date: 26 February 2021

Serum Exosomal miRNA-1226 as Potential Biomarker of Pancreatic Ductal Adenocarcinoma

Wang C, Wang J, Cui W, Liu Y, Zhou H, Wang Y, Chen X, Chen X, Wang Z

OncoTargets and Therapy 2021, 14:1441-1451

Published Date: 26 February 2021

TRIM11 Promotes Proliferation, Migration, Invasion and EMT of Gastric Cancer by Activating β-Catenin Signaling

Lan Q, Tan X, He P, Li W, Tian S, Dong W

OncoTargets and Therapy 2021, 14:1429-1440

Published Date: 25 February 2021

Research Trends and Regulation of CCL5 in Prostate Cancer

Huang R, Guo L, Gao M, Li J, Xiang S

OncoTargets and Therapy 2021, 14:1417-1427

Published Date: 25 February 2021

Renal Transcriptomics Reveals the Carcinogenic Mechanism of Ethyl Carbamate in Musalais

Wang W, Han ZJ, Guo D, Xiang Y

OncoTargets and Therapy 2021, 14:1401-1416

Published Date: 25 February 2021

Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis

Li L, Wang Z, Lu T, Li Y, Pan M, Yu D, Hu G

OncoTargets and Therapy 2021, 14:1387-1399

Published Date: 25 February 2021

Expression and Prognostic Value of Tumor-Infiltrating Lymphocytes and PD-L1 in Hepatocellular Carcinoma

Nie H, He T, Wang L, Zhang L

OncoTargets and Therapy 2021, 14:1377-1385

Published Date: 25 February 2021

Secondary Nasopharyngeal Mixed Adenoneuroendocrine Carcinoma After Radical Radiotherapy for Nasopharyngeal Carcinoma: A Rare Case and Literature Review

Huang D, Huang C, Wang H, He L, Zhang J, Zhong X, Guo Z, Yuan Y, Zhang W

OncoTargets and Therapy 2021, 14:1367-1376

Published Date: 25 February 2021

Near-Infrared Light-Triggered Thermosensitive Liposomes Modified with Membrane Peptides for the Local Chemo/Photothermal Therapy of Melanoma

Li X, Yang C, Tao Y, Hou X, Liu Y, Sang H, Jiang G

OncoTargets and Therapy 2021, 14:1317-1329

Published Date: 25 February 2021

Increased HSF1 Promotes Infiltration and Metastasis in Cervical Cancer via Enhancing MTDH-VEGF-C Expression

Shi X, Deng Z, Wang S, Zhao S, Xiao L, Zou J, Li T, Tan S, Tan S, Xiao X

OncoTargets and Therapy 2021, 14:1305-1315

Published Date: 26 February 2021

Anti-Proliferative, Pro-Apoptotic, Anti-Migrative and Tumor-Inhibitory Effects and Pleiotropic Mechanism of Theaflavin on B16F10 Melanoma Cells

Zhang L, Meng S, Yan B, Chen J, Zhou L, Shan L, Wang Y

OncoTargets and Therapy 2021, 14:1291-1304

Published Date: 25 February 2021

Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC)

Huang G, Wu Q, Zheng Z, Shao T, Li F, Lu X, Ye H, Chen G, Song Y, Zeng W, Ai Y, Lv X

OncoTargets and Therapy 2021, 14:1275-1289

Published Date: 25 February 2021

Ouabain Exhibited Strong Anticancer Effects in Melanoma Cells via Induction of Apoptosis, G2/M Phase Arrest, and Migration Inhibition

Wang L, Cai W, Han B, Zhang J, Yu B, Chen M

OncoTargets and Therapy 2021, 14:1261-1273

Published Date: 25 February 2021

TRPM2-AS Promotes Bladder Cancer by Targeting miR-22-3p and Regulating GINS2 mRNA Expression

Tian Y, Guan Y, Su Y, Yang T, Yu H

OncoTargets and Therapy 2021, 14:1219-1237

Published Date: 23 February 2021

Cancer-Associated Fibroblasts Positively Correlate with Dedifferentiation and Aggressiveness of Thyroid Cancer

Wen S, Qu N, Ma B, Wang X, Luo Y, Xu W, Jiang H, Zhang Y, Wang Y, Ji Q

OncoTargets and Therapy 2021, 14:1205-1217

Published Date: 22 February 2021

KDM5C Expedites Lung Cancer Growth and Metastasis Through Epigenetic Regulation of MicroRNA-133a

Zhang Q, Xu L, Wang J, Zhu X, Ma Z, Yang J, Li J, Jia X, Wei L

OncoTargets and Therapy 2021, 14:1187-1204

Published Date: 22 February 2021

Novel lncRNA LINC00941 Promotes Proliferation and Invasion of Colon Cancer Through Activation of MYC

Chang L, Zhou D, Luo S

OncoTargets and Therapy 2021, 14:1173-1186

Published Date: 22 February 2021

miR-744-5p Inhibits Multiple Myeloma Proliferation, Epithelial Mesenchymal Transformation and Glycolysis by Targeting SOX12/Wnt/β-Catenin Signaling

Guo B, Xiao C, Liu Y, Zhang N, Bai H, Yang T, Xiang Y, Nan Y, Li Q, Zhang W, Huang D

OncoTargets and Therapy 2021, 14:1161-1172

Published Date: 22 February 2021

LINC00466 Impacts Cell Proliferation, Metastasis and Sensitivity to Temozolomide of Glioma by Sponging miR-137 to Regulate PPP1R14B Expression

Zhao M, Shao Y, Xu J, Zhang B, Li C, Gong J

OncoTargets and Therapy 2021, 14:1147-1159

Published Date: 19 February 2021

Poor Prognosis of Pulmonary Adenosquamous Carcinoma with NRAS and HRAS Double Mutation

Zhao J, Zhang X, He M, Chen X, Cui X, Qin T, Niu X, Zhao L

OncoTargets and Therapy 2021, 14:1113-1116

Published Date: 17 February 2021

Prognostic Significance of the Combination of Fibrinogen and Tumor Marker Index in Esophageal Squamous Cell Carcinoma Patients

Qiao Y, Ma M, Zhang H, Yu Z, Tang P

OncoTargets and Therapy 2021, 14:1101-1111

Published Date: 17 February 2021

Pulmonary Lymphoepithelioma-Like Carcinoma Treated with Immunotherapy or Chemotherapy: A Single Institute Experience

Fu Y, Zheng Y, Wang PP, Chen YY, Ding ZY

OncoTargets and Therapy 2021, 14:1073-1081

Published Date: 16 February 2021

Transiently Elevated TC and sdLDL-C Levels and Falsely Low LDL-C Levels in Patients with Extrahepatic Cholangiocarcinoma

Guo Y, Zhang YG, Li HC, Xu YH

OncoTargets and Therapy 2021, 14:1061-1071

Published Date: 15 February 2021

AG-1024 Sensitizes Sorafenib-Resistant Hepatocellular Carcinoma Cells to Sorafenib via Enhancing G1/S Arrest

Zhou W, Lou W, Chen J, Ding B, Chen B, Xie H, Zhou L, Zheng S, Jiang D

OncoTargets and Therapy 2021, 14:1049-1059

Published Date: 15 February 2021

Exonuclease 1 (EXO1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Lung Adenocarcinoma

Zhou CS, Feng MT, Chen X, Gao Y, Chen L, Li LD, Li DH, Cao YQ

OncoTargets and Therapy 2021, 14:1033-1048

Published Date: 15 February 2021

Comprehensive Analysis of Gene Expression Changes and Validation in Hepatocellular Carcinoma

Zhang H, Liu R, Sun L, Guo W, Ji X, Hu X

OncoTargets and Therapy 2021, 14:1021-1031

Published Date: 15 February 2021

Tandem Mass Tag-Based Proteomic Analysis of Potential Biomarkers for Hepatocellular Carcinoma Differentiation

Wang W, Li Q, Huang G, Lin BY, Lin D, Ma Y, Zhang Z, Chen T, Zhou J

OncoTargets and Therapy 2021, 14:1007-1020

Published Date: 12 February 2021

A Case Report: Cutaneous Metastasis of Advanced Rectal Cancer with BRAF Mutation

Zhou S, Tang W, Wang Q, Zhang X, Jin X, Xu X, Fu J

OncoTargets and Therapy 2021, 14:989-993

Published Date: 11 February 2021

Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer

Wang G, Wang X, Han M, Wang X

OncoTargets and Therapy 2021, 14:979-988

Published Date: 11 February 2021

IgG Fc Binding Protein (FCGBP) is Down-Regulated in Metastatic Lesions and Predicts Survival in Metastatic Colorectal Cancer Patients

Yuan Z, Zhao Z, Hu H, Zhu Y, Zhang W, Tang Q, Huang R, Gao F, Zou C, Wang G, Wang X

OncoTargets and Therapy 2021, 14:967-977

Published Date: 11 February 2021

Extragastrointestinal Stromal Tumor Presenting as a Recurrent Vaginal Mass: Case Report

Liu S, Pan P, Han B, Wang J, Sun M, Sun Y

OncoTargets and Therapy 2021, 14:959-965

Published Date: 10 February 2021

Malignant Acanthosis Nigricans with Recurrent Bladder Cancer: A Case Report and Review of Literature

Zhang R, Jiang M, Lei W, Wang A

OncoTargets and Therapy 2021, 14:951-957

Published Date: 10 February 2021

TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT

Huang Z, Yan Y, Tang P, Cai J, Cao X, Wang Z, Zhang F, Shen B

OncoTargets and Therapy 2021, 14:937-949

Published Date: 10 February 2021

Research Progress on Regulating LncRNAs of Hepatocellular Carcinoma Stem Cells

Zhang X, Zhu Y

OncoTargets and Therapy 2021, 14:917-927

Published Date: 10 February 2021

Circular RNA circARPP21 Acts as a Sponge of miR-543 to Suppress Hepatocellular Carcinoma by Regulating LIFR

Gu Y, Wu F, Wang H, Chang J, Wang Y, Li X

OncoTargets and Therapy 2021, 14:879-890

Published Date: 5 February 2021

Screening of Therapeutic Candidate Genes of Quercetin for Cervical Cancer and Analysis of Their Regulatory Network

Li Y, Kou J, Wu T, Zheng P, Chao X

OncoTargets and Therapy 2021, 14:857-866

Published Date: 5 February 2021

Combination Therapy with iRGD-antiCD3 and PD-1 Blockade Enhances Antitumor Potency of Cord Blood-Derived T Cells

Zhu M, Wang H, Zhou S, Wei J, Ding N, Shao J, Yu L, Feng Z, Liu B

OncoTargets and Therapy 2021, 14:835-844

Published Date: 5 February 2021

Sinomenine Inhibits the Growth of Ovarian Cancer Cells Through the Suppression of Mitosis by Down-Regulating the Expression and the Activity of CDK1

Qu X, Yu B, Zhu M, Li X, Ma L, Liu C, Zhang Y, Cheng Z

OncoTargets and Therapy 2021, 14:823-834

Published Date: 5 February 2021

Identification of a Six-Gene Signature for Predicting the Overall Survival of Cervical Cancer Patients

Huo X, Zhou X, Peng P, Yu M, Zhang Y, Yang J, Cao D, Sun H, Shen K

OncoTargets and Therapy 2021, 14:809-822

Published Date: 5 February 2021

Triple Discordances in Receptor Status During Breast Cancer Local Progression and Metastases: Case Report and Literature Review [Erratum]

Martuszewski A, Paluszkiewicz P, Nowak M, Szewczyk K, Staszek-Szewczyk U

OncoTargets and Therapy 2021, 14:807-808

Published Date: 4 February 2021

LncRNA FER1L4 Promotes Oral Squamous Cell Carcinoma Progression via Targeting miR-133a-5p/Prx1 Axis

Zhang N, Zeng L, Wang S, Wang R, Yang R, Jin Z, Tao H

OncoTargets and Therapy 2021, 14:795-806

Published Date: 4 February 2021

Development of a Novel Highly Spontaneous Metastatic Model of Esophageal Squamous Cell Carcinoma Using Renal Capsule Technology

Gao P, Liu H, Yang Z, Hui Y, Shi Z, Yang Z, Song M, Yao M, Fan W, Yang J, Hao Y, Fan T

OncoTargets and Therapy 2021, 14:785-793

Published Date: 4 February 2021

Hypofractionated Low-Dose Radiotherapy Combined with Immune Checkpoint Inhibition in Metastatic Solid Tumors

Li D, Zhu W, Zhou J, Peng M, Geng Q, Pu X, Wang M, Jiang H

OncoTargets and Therapy 2021, 14:773-783

Published Date: 4 February 2021

Long Noncoding RNA JAKMIP2-AS1 Promotes the Growth of Colorectal Cancer and Indicates Poor Prognosis

Ma T, Qiao T, Yuan Z, Wang G, Huang R, Wang M, Hu H, Zhu Y, Zou X, Wang X

OncoTargets and Therapy 2021, 14:763-772

Published Date: 3 February 2021

LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis

Gao Q, Huang Q, Li F, Luo F

OncoTargets and Therapy 2021, 14:751-761

Published Date: 3 February 2021

LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail

Yuan S, Si W, Zhuang K, Li Y, Zhang Y, Liu J, Yang L, Zhang X

OncoTargets and Therapy 2021, 14:725-736

Published Date: 28 January 2021

Identification of Critical Pathways and Potential Key Genes in Poorly Differentiated Pancreatic Adenocarcinoma

Lu Y, Li D, Liu G, Xiao E, Mu S, Pan Y, Qin F, Zhai Y, Duan S, Li D, Yan G

OncoTargets and Therapy 2021, 14:711-723

Published Date: 27 January 2021

CPNE1 Enhances Colorectal Cancer Cell Growth, Glycolysis, and Drug Resistance Through Regulating the AKT-GLUT1/HK2 Pathway

Wang Y, Pan S, He X, Wang Y, Huang H, Chen J, Zhang Y, Zhang Z, Qin X

OncoTargets and Therapy 2021, 14:699-710

Published Date: 27 January 2021

Chrysin Induced Cell Apoptosis and Inhibited Invasion Through Regulation of TET1 Expression in Gastric Cancer Cells [Corrigendum]

Zhong X, Liu D, Jiang Z, Li C, Chen L, Xia Y, Liu D, Yao Q, Wang D

OncoTargets and Therapy 2021, 14:697-698

Published Date: 26 January 2021

LINC01278 is Highly Expressed in Osteosarcoma and Participates in the Development of Tumors by Mediating the miR-134-5p/KRAS Axis

Zhang GF, Zhou BS, An XC, An FM, Li SH

OncoTargets and Therapy 2021, 14:683-695

Published Date: 26 January 2021

Role of Antizyme Inhibitor Proteins in Cancers and Beyond

Tulluri V, Nemmara VV

OncoTargets and Therapy 2021, 14:667-682

Published Date: 25 January 2021

Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3

Chen B, Dong C, Wang F, Wu J

OncoTargets and Therapy 2021, 14:637-651

Published Date: 22 January 2021

Decitabine and Cisplatin are Synergistic to Exert Anti-Tumor Effect on Gastric Cancer via Inducing Sox2 DNA Demethylation

Zhu Z, Lin S, Wu X, Xu J, Li L, Ye W, Li J, Huang Z

OncoTargets and Therapy 2021, 14:623-636

Published Date: 22 January 2021

Identification and Targeting of Thomsen–Friedenreich and IL1RAP Antigens on Chronic Myeloid Leukemia Stem Cells Using Bi-Specific Antibodies

Eldesouki RE, Wu C, Saleh FM, Mohammed EAM, Younes S, Hassan NE, Brown TC, Alt EU, Robinson JE, Badr FM, Braun SE

OncoTargets and Therapy 2021, 14:609-621

Published Date: 22 January 2021

Low Expression of Keratin17 is Related to Poor Prognosis in Bladder Cancer

Wu J, Xu H, Ji H, Zhai B, Zhu J, Gao M, Zhu H, Wang X

OncoTargets and Therapy 2021, 14:577-587

Published Date: 19 January 2021

LncRNA ANRIL Regulates Ovarian Cancer Progression and Tumor Stem Cell-Like Characteristics via miR-324-5p/Ran Axis

Wang K, Hu YB, Zhao Y, Ye C

OncoTargets and Therapy 2021, 14:565-576

Published Date: 19 January 2021

Propofol Inhibits the Progression of Cervical Cancer by Regulating HOTAIR/miR-129-5p/RPL14 Axis

Sun N, Zhang W, Liu J, Yang X, Chu Q

OncoTargets and Therapy 2021, 14:551-564

Published Date: 19 January 2021

Gastric Cancer Harboring an ERBB3 Mutation Treated with a Pyrotinib–Irinotecan Combo: A Case Study

Ding K, Chen X, Li Y, Li W, Ye Y, He T, Wang W, Zhang H

OncoTargets and Therapy 2021, 14:545-550

Published Date: 18 January 2021

lncRNA RAET1K Promotes the Progression of Acute Myeloid Leukemia by Targeting miR-503-5p/INPP4B Axis

Li L, Wan D, Li L, Qin Y, Ma W

OncoTargets and Therapy 2021, 14:531-544

Published Date: 18 January 2021

Role of Long Non-Coding RNAs in the Chemoresistance of Gastric Cancer: A Systematic Review

Li Z, Lü M, Zhou Y, Xu L, Jiang Y, Liu Y, Li X, Song M

OncoTargets and Therapy 2021, 14:503-518

Published Date: 18 January 2021

Circ_0067835 Knockdown Enhances the Radiosensitivity of Colorectal Cancer by miR-296-5p/IGF1R Axis

Wang P, Sun Y, Yang Y, Chen Y, Liu H

OncoTargets and Therapy 2021, 14:491-502

Published Date: 18 January 2021

PD-1 Expression in Pre-Treatment Follicular Lymphoma Predicts the Risk of Subsequent High-Grade Transformation

Beck Enemark M, Monrad I, Madsen C, Lystlund Lauridsen K, Honoré B, Plesner TL, Hamilton-Dutoit SJ, d'Amore F, Ludvigsen M

OncoTargets and Therapy 2021, 14:481-489

Published Date: 18 January 2021

Neutral Desorption Extractive Electrospray Ionization Mass Spectrometry Analysis Sputum for Non-Invasive Lung Adenocarcinoma Detection

Zheng Q, Zhang J, Wang X, Zhang W, Xiao Y, Hu S, Xu J

OncoTargets and Therapy 2021, 14:469-479

Published Date: 15 January 2021

MicroRNA-1252-5p Associated with Extracellular Vesicles Enhances Bortezomib Sensitivity in Multiple Myeloma Cells by Targeting Heparanase

Rodrigues-Junior DM, Pelarin MFA, Nader HB, Vettore AL, Pinhal MAS

OncoTargets and Therapy 2021, 14:455-467

Published Date: 15 January 2021

O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness

Chen Y, Liu J, Zhang W, Kadier A, Wang R, Zhang H, Yao X

OncoTargets and Therapy 2021, 14:445-454

Published Date: 15 January 2021

HSDL2 Acts as a Promoter in Pancreatic Cancer by Regulating Cell Proliferation and Lipid Metabolism

Han A, Xu R, Liu Y, Yin X, Lin Z, Yang W

OncoTargets and Therapy 2021, 14:435-444

Published Date: 14 January 2021

Combined Serum DKK3 and Circulating CD133 Cells as Prognostic Biomarkers for Ovarian Cancer Patients

Nie XC, He F, Lan C, Niu JM, Xia P

OncoTargets and Therapy 2021, 14:427-434

Published Date: 14 January 2021

Establishment of a Risk Signature Based on m6A RNA Methylation Regulators That Predicts Poor Prognosis in Renal Cell Carcinoma

Wei J, Qian Y, Tang Y, Ge X, Jiang K, Fang Y, Fu D, Kong X, Xiao Q, Ding K

OncoTargets and Therapy 2021, 14:413-426

Published Date: 14 January 2021

The Value and Clinical Significance of ZNF582 Gene Methylation in the Diagnosis of Cervical Cancer

Zhang C, Fu S, Wang L, Wang F, Wu D, Zhe X, Xin H, Li H, Li D, Jin F, Shao R, Pan Z

OncoTargets and Therapy 2021, 14:403-411

Published Date: 14 January 2021

Long Non-Coding RNA PCED1B-AS1 Promotes the Progression of Clear Cell Renal Cell Carcinoma Through miR-484/ZEB1 Axis

Qin J, Zhu T, Wu W, Chen H, He Y

OncoTargets and Therapy 2021, 14:393-402

Published Date: 13 January 2021

Aberrant SLC6A14 Expression Promotes Proliferation and Metastasis of Colorectal Cancer via Enhancing the JAK2/STAT3 Pathway

Mao H, Sheng J, Jia J, Wang C, Zhang S, Li H, He F

OncoTargets and Therapy 2021, 14:379-392

Published Date: 13 January 2021

LncRNA EWSAT1 Promotes Colorectal Cancer Progression Through Sponging miR-326 to Modulate FBXL20 Expression

Liu J, Huang S, Liao X, Chen Z, Li L, Yu L, Zhan W, Li R

OncoTargets and Therapy 2021, 14:367-378

Published Date: 13 January 2021

CRNDE Contributes Cervical Cancer Progression by Regulating miR-4262/ZEB1 Axis

Ren L, Yang S, Cao Q, Tian J

OncoTargets and Therapy 2021, 14:355-366

Published Date: 13 January 2021

Case Report: Myeloid Sarcoma Development During Treatment for B Cell Lymphoblastic Lymphoma in a Boy with KRAS/NRAS Gene Mutations

Yuan X, Yu U, Chen S, Xu H, Yi M, Jiang X, Song J, Chen X, Chen S, Lin Z, Li C, Wen F, Liu S

OncoTargets and Therapy 2021, 14:347-353

Published Date: 13 January 2021

miR-21 Induces Chemoresistance in Ovarian Cancer Cells via Mediating the Expression and Interaction of CD44v6 and P-gp

Wang Y, Chen G, Dai F, Zhang L, Yuan M, Yang D, Liu S, Cheng Y

OncoTargets and Therapy 2021, 14:325-336

Published Date: 12 January 2021

Further Understanding of Urokinase Plasminogen Activator Overexpression in Urothelial Bladder Cancer Progression, Clinical Outcomes and Potential Therapeutic Targets

Grossmann NC, Schuettfort VM, Pradere B, Moschini M, Quhal F, Mostafaei H, Soria F, Katayama S, Laukhtina E, Mori K, Sari Motlagh R, Poyet C, Abufaraj M, Karakiewicz PI, Shariat SF, D’Andrea D

OncoTargets and Therapy 2021, 14:315-324

Published Date: 13 January 2021

Physalis alkekengi var. franchetii Extracts Exert Antitumor Effects on Non-Small Cell Lung Cancer and Multiple Myeloma by Inhibiting STAT3 Signaling

Fu Y, Zhu F, Ma Z, Lv B, Wang X, Dai C, Ma X, Liu P, Lv H, Chen X, Chen Z, Shen L

OncoTargets and Therapy 2021, 14:301-314

Published Date: 12 January 2021

The Biological Roles of Exosomal Long Non-Coding RNAs in Cancers

Da M, Jiang H, Xie Y, Jin W, Han S

OncoTargets and Therapy 2021, 14:271-287

Published Date: 12 January 2021

GADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial–Mesenchymal Transition

Gong L, Cai L, Li G, Cai J, Yi X

OncoTargets and Therapy 2021, 14:255-269

Published Date: 12 January 2021

Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy

Lu Y, Li L, Chen H, Jing X, Wang M, Ge L, Yang J, Zhang M, Tang X

OncoTargets and Therapy 2021, 14:239-251

Published Date: 12 January 2021

The Plasma Concentration of D-Dimer is Associated with Neoadjuvant-Chemotherapy Efficacy and the Prognosis in Osteosarcoma

Huang Y, Shen Z, Yao Y, He A, Min D

OncoTargets and Therapy 2021, 14:213-220

Published Date: 11 January 2021

A Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells

Lv X, Zhang J, Zhang J, Guan W, Ren W, Liu Y, Xu G

OncoTargets and Therapy 2021, 14:187-198

Published Date: 8 January 2021

Multi Cytogenetic Changes in a Patient as Co-Existing MDS and CLL Progresses

Li X, Ma J, Wang L, Yan S, Li F, Wang L, Wang L, Li G, Ma D, Li H

OncoTargets and Therapy 2021, 14:177-186

Published Date: 8 January 2021

LncRNA DDX11-AS1 Exerts Oncogenic Roles in Glioma Through Regulating miR-499b-5p/RWDD4 Axis

Zheng Y, Xie J, Xu X, Yang X, Zhou Y, Yao Q, Xiong Y

OncoTargets and Therapy 2021, 14:157-164

Published Date: 8 January 2021

ALYREF Drives Cancer Cell Proliferation Through an ALYREF-MYC Positive Feedback Loop in Glioblastoma

Wang J, Li Y, Xu B, Dong J, Zhao H, Zhao D, Wu Y

OncoTargets and Therapy 2021, 14:145-155

Published Date: 8 January 2021

Rare Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review

Wang N, Dong SS, Wu CL, Wang Y, Meng L, Ren Y, Cui XB, Li M, Qi Y

OncoTargets and Therapy 2021, 14:139-144

Published Date: 8 January 2021

PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma

Li H, Liu Q, Xiao K, He Z, Wu C, Sun J, Chen X, Chen S, Yang J, Ma Q, Su J

OncoTargets and Therapy 2021, 14:125-138

Published Date: 8 January 2021

Exosomal miR-638 Inhibits Hepatocellular Carcinoma Progression by Targeting SP1 [Retraction]

Yang J, Li B, Zhao S, Du H, Du Y

OncoTargets and Therapy 2021, 14:123-124

Published Date: 8 January 2021

Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene

Luo Y, Yu P, Zhao J, Guo Q, Fan B, Diao Y, Jin Y, Wu J, Zhang C

OncoTargets and Therapy 2021, 14:111-122

Published Date: 7 January 2021

Circ_0007444 Inhibits the Progression of Ovarian Cancer via Mediating the miR-570-3p/PTEN Axis

Wu X, Liu D, Wang S, Liu J

OncoTargets and Therapy 2021, 14:97-110

Published Date: 7 January 2021

Circ_0006404 Accelerates Prostate Cancer Progression Through Regulating miR-1299/CFL2 Signaling

Li P, Wang Z, Li S, Wang L

OncoTargets and Therapy 2021, 14:83-95

Published Date: 6 January 2021

Silencing of MicroRNA-503 in Rat Mesenchymal Stem Cells Exerts Potent Antitumorigenic Effects in Lung Cancer Cells

Huang B, Feng Z, Zhu L, Zhang S, Duan J, Zhao C, Zhang X

OncoTargets and Therapy 2021, 14:67-81

Published Date: 6 January 2021

Aberrant Factors of Fibrinolysis and Coagulation in Pancreatic Cancer

Fang L, Xu Q, Qian J, Zhou JY

OncoTargets and Therapy 2021, 14:53-65

Published Date: 6 January 2021

Clinicopathological and Prognostic Significance of Immunoscore and PD-L1 in Intrahepatic Cholangiocarcinoma

Wu H, Wei Y, Jian M, Lu H, Song Q, Hao L, Yue Y

OncoTargets and Therapy 2021, 14:39-51

Published Date: 6 January 2021

Prognostic Value of Pretreatment Serum Cystatin C Level in Nasopharyngeal Carcinoma Patients in the Intensity-modulated Radiotherapy Era

Tan XR, Huang SY, Gong S, Chen Y, Yang XJ, He QM, He SW, Liu N, Li YQ

OncoTargets and Therapy 2021, 14:29-37

Published Date: 6 January 2021

MiRNA-1225 Inhibits Osteosarcoma Tumor Growth and Progression by Targeting YWHAZ

Gong Y, Wei Z, Liu J

OncoTargets and Therapy 2021, 14:15-27

Published Date: 6 January 2021