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Neuropsychiatric Disease and Treatment
ISSN: 1178-2021
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Archive: Volume 17, 2021
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- Cariprazine in schizophrenia (5)
Adverse Drug Reaction and Its Predictors Among Psychiatric Patients Taking Psychotropic Medications at the Mizan-Tepi University Teaching Hospital
Ejeta F, Aferu T, Feyisa D, Kebede O, Siraj J, Hammeso WW, Tadesse E, Tinishku A
Neuropsychiatric Disease and Treatment 2021, 17:3827-3835
Published Date: 29 December 2021
Fluoxetine May Enhance VEGF, BDNF and Cognition in Patients with Vascular Cognitive Impairment No Dementia: An Open-Label Randomized Clinical Study
Zhang L, Liu X, Li T, Xu B, Fu B
Neuropsychiatric Disease and Treatment 2021, 17:3819-3825
Published Date: 29 December 2021

QTc Interval Prolongation with Therapies Used to Treat Patients with Parkinson’s Disease Psychosis: A Narrative Review
Torres-Yaghi Y, Carwin A, Carolan J, Nakano S, Amjad F, Pagan F
Neuropsychiatric Disease and Treatment 2021, 17:3791-3818
Published Date: 24 December 2021

Therapeutic Potential of Vortioxetine for Anxious Depression: A Post Hoc Analysis of Data from a Clinical Trial Conducted in Japan
Inoue T, Fujimoto S, Marumoto T, Kitagawa T, Ishida K, Nakajima T, Moriguchi Y, Fujikawa K, Watanabe K
Neuropsychiatric Disease and Treatment 2021, 17:3781-3790
Published Date: 21 December 2021
EMT-Related Markers in Serum Exosomes are Potential Diagnostic Biomarkers for Invasive Pituitary Adenomas

Chen K, Li G, Kang X, Liu P, Qian L, Shi Y, Osman RA, Yang Z, Zhang G
Neuropsychiatric Disease and Treatment 2021, 17:3769-3780
Published Date: 21 December 2021
Resting-State Functional Magnetic Resonance Imaging Reveals Overactivation of the Habitual Control Brain System in Tobacco Dependence
Tan Q, Li S, Niu J, Liu S, Li Y, Lu Y, Wang Z, Xu W, Wei Y, Guo Z
Neuropsychiatric Disease and Treatment 2021, 17:3753-3768
Published Date: 19 December 2021
Physical Activity and Motor Performance: A Comparison Between Young Children With and Without Autism Spectrum Disorder
Sung YS, Loh SC, Lin LY
Neuropsychiatric Disease and Treatment 2021, 17:3743-3751
Published Date: 18 December 2021

Early Improvement with Vortioxetine Predicts Response and Remission: A Post Hoc Analysis of Data from a Clinical Trial Conducted in Japan
Inoue T, Fujimoto S, Marumoto T, Kitagawa T, Ishida K, Nakajima T, Moriguchi Y, Fujikawa K, Watanabe K
Neuropsychiatric Disease and Treatment 2021, 17:3735-3741
Published Date: 18 December 2021
Effect of Deep Brain Stimulation on Female Parkinsonian Patients with Lower Urinary Tract Symptoms
Liang F, Tang Y, Bi K, Liu X, Li C, Chen S, Zhang C, Yan L, Xu Z, Yang N
Neuropsychiatric Disease and Treatment 2021, 17:3727-3733
Published Date: 18 December 2021
Prescriber Attitudes, Experiences, and Proclivities Toward Digital Medicine and How They Influence Adoption of Digital Medicine Platforms
Ruetsch C, Davis T, Liberman JN, Velligan DI, Robinson D, Jaeger C, Carpenter W, Forma F
Neuropsychiatric Disease and Treatment 2021, 17:3715-3726
Published Date: 16 December 2021
Well-Water Consumption and Risk of Parkinson’s Disease: A Meta-Analysis of 15 Observational Studies
Shi Y, Zhang K, Ye M
Neuropsychiatric Disease and Treatment 2021, 17:3705-3714
Published Date: 16 December 2021
Selective Impairment of Processing Task-Irrelevant Emotional Faces in Cerebral Small Vessel Disease Patients
Fan Z, Guo Y, Hou X, Lv R, Nie S, Xu S, Chen J, Hong Y, Zhao S, Liu X
Neuropsychiatric Disease and Treatment 2021, 17:3693-3703
Published Date: 16 December 2021
Paliperidone Compared with Haloperidol on the Theory of Mind Tasks in Schizophrenia: A Pilot Trial
Zhong J, Zhu H, Yin D, Ning Y, Zheng S, Zhang Y, Jia H
Neuropsychiatric Disease and Treatment 2021, 17:3683-3691
Published Date: 14 December 2021

The Relationship Between Khat Use Disorder and Post-Traumatic Stress Disorder Among Prisoners with Life Time Trauma Exposure in Ethiopia: A Cross-Sectional Study
Wolde A
Neuropsychiatric Disease and Treatment 2021, 17:3669-3681
Published Date: 14 December 2021

From Personalized Medicine to Precision Psychiatry?
Češková E, Šilhán P
Neuropsychiatric Disease and Treatment 2021, 17:3663-3668
Published Date: 14 December 2021
Treatment Continuation of Asenapine or Olanzapine in Japanese Schizophrenia Patients: A Propensity Score Matched Study
Matsuzaki H, Hatano M, Iwata M, Yamada S
Neuropsychiatric Disease and Treatment 2021, 17:3655-3661
Published Date: 14 December 2021
Prevalence, Influencing Factors, and Cognitive Characteristics of Depressive Symptoms in Elderly Patients with Schizophrenia
Chen Y, Li W
Neuropsychiatric Disease and Treatment 2021, 17:3645-3654
Published Date: 14 December 2021
The Mediating Role of Self-Efficacy in Sleep Disorder and Depressive Symptoms Among Chinese Caregivers of Stroke Inpatients: A Structural Equation Modeling Analysis
Cong L, Ju Y, Gui L, Zhang B, Ding F, Zou C
Neuropsychiatric Disease and Treatment 2021, 17:3635-3643
Published Date: 14 December 2021
Frontline Nurses’ Post-Traumatic Stress Disorder and Associated Predictive Factors During the Second Wave of COVID-19 in Central, Uganda
Kabunga A, Okalo P
Neuropsychiatric Disease and Treatment 2021, 17:3627-3633
Published Date: 14 December 2021
LncRNA FTX Regulates Angiogenesis Through miR-342-3p/SPI1 Axis in Stroke
Gao Q, Wang Y
Neuropsychiatric Disease and Treatment 2021, 17:3617-3625
Published Date: 11 December 2021
Relationship Among Homocysteine, Inflammation and Cognitive Impairment in Patients with Acute Ischemic Stroke and Transient Ischemic Attack
Cui L, Lu P, Li S, Pan Y, Wang M, Li Z, Liao X, Wang Y
Neuropsychiatric Disease and Treatment 2021, 17:3607-3616
Published Date: 11 December 2021
Relationships Among Retinal Nerve Fiber Layer Thickness, Vascular Endothelial Growth Factor, and Cognitive Impairment in Patients with Schizophrenia
Liu Y, Chen J, Huang L, Yan S, Bian Q, Yang F
Neuropsychiatric Disease and Treatment 2021, 17:3597-3606
Published Date: 9 December 2021

Neutrophil-to-Lymphocyte Ratio Better Than High-Sensitivity C-Reactive Protein in Predicting Stroke-Associated Pneumonia in Afebrile Patients
Wu T, Zhang H, Tian X, Cao Y, Wei D, Wu X
Neuropsychiatric Disease and Treatment 2021, 17:3589-3595
Published Date: 9 December 2021


Cariprazine in Three Special Different Areas: A Real-World Experience
Gesi C, Paletta S, Palazzo M C, Dell'Osso B, Mencacci C, Cerveri G
Neuropsychiatric Disease and Treatment 2021, 17:3581-3588
Published Date: 7 December 2021
MRI Evaluation of the Relationship Between Abnormalities in Vision-Related Brain Networks and Quality of Life in Patients with Migraine without Aura
Cui W, Zhang J, Xu F, Zhi H, Li H, Li B, Zhang S, Peng W, Wu H
Neuropsychiatric Disease and Treatment 2021, 17:3569-3579
Published Date: 8 December 2021
The Role of PAX2 in Neurodevelopment and Disease
Lv N, Wang Y, Zhao M, Dong L, Wei H
Neuropsychiatric Disease and Treatment 2021, 17:3559-3567
Published Date: 7 December 2021


Alterations in Peripheral C-Reactive Protein and Inflammatory Cytokine Levels in Patients with Panic Disorder: A Systematic Review and Meta-Analysis
Liu CH, Hua N, Yang HY
Neuropsychiatric Disease and Treatment 2021, 17:3539-3558
Published Date: 7 December 2021
Association of Versican Gene Polymorphisms with Intracranial Aneurysm Susceptibility in the Eastern Chinese Population
Zhu L, Yu C, Zhou S, Xue M, Chen J, Wu M, Dong S, Huang G, Chang Y, Zhang M
Neuropsychiatric Disease and Treatment 2021, 17:3531-3537
Published Date: 7 December 2021

Challenges Surrounding the Diagnosis of Autism in Children
Hus Y, Segal O
Neuropsychiatric Disease and Treatment 2021, 17:3509-3529
Published Date: 3 December 2021
Sleep Disturbances and Associated Factors in Drug-Naïve Patients with Parkinson’s Disease
Zhong M, Jiang X, Zhu S, Gu R, Bai Y, He H, Pan Y, Xu P, Yan J, Zhang L
Neuropsychiatric Disease and Treatment 2021, 17:3499-3508
Published Date: 3 December 2021

The Relationship Between Antipsychotic-Induced Akathisia and Suicidal Behaviour: A Systematic Review
Kalniunas A, Chakrabarti I, Mandalia R, Munjiza J, Pappa S
Neuropsychiatric Disease and Treatment 2021, 17:3489-3497
Published Date: 3 December 2021

Reduced Plasma Estradiol Levels are Associated with Sleep Apnea in Depressed Peri- and Post-Menopausal Women
Cai L, Huang L, Wei L, Yao J, Xu L, Chen W
Neuropsychiatric Disease and Treatment 2021, 17:3483-3488
Published Date: 2 December 2021
Predictors of Neurological Presentations of COVID-19 Infected Patients in South Egypt, Aswan Governorate: A Single Center Study
Tony AA, Ahmed SBA, Tony EAE, Maklad S, Elnakeeb I, Amin MM
Neuropsychiatric Disease and Treatment 2021, 17:3471-3482
Published Date: 1 December 2021

Effect of Sleep Disturbance on Efficacy of Esketamine in Treatment-Resistant Depression: Findings from Randomized Controlled Trials
Borentain S, Williamson D, Turkoz I, Popova V, McCall WV, Mathews M, Wiegand F
Neuropsychiatric Disease and Treatment 2021, 17:3459-3470
Published Date: 30 November 2021

Critical Appraisal of Cenobamate as Adjunctive Treatment of Focal Seizures in Adults
Zaccara G, Lattanzi S, Leo A, Russo E
Neuropsychiatric Disease and Treatment 2021, 17:3447-3457
Published Date: 30 November 2021

Rumination Mediates the Effects of Childhood Maltreatment and Trait Anxiety on Depression in Non-Clinical Adult Volunteers
Deguchi A, Masuya J, Naruse M, Morishita C, Higashiyama M, Tanabe H, Inoue T, Ichiki M
Neuropsychiatric Disease and Treatment 2021, 17:3439-3445
Published Date: 23 November 2021
Analysis of Risk Factors for Poor Short-Term Outcomes in Acute Cardioembolic Stroke Patients without Reperfusion Therapy
Guo Y, Zhang M, Su Y, Liu J, Fu H, Wang Q, Chen Y
Neuropsychiatric Disease and Treatment 2021, 17:3431-3437
Published Date: 23 November 2021

Screening for Depression in Mobile Devices Using Patient Health Questionnaire-9 (PHQ-9) Data: A Diagnostic Meta-Analysis via Machine Learning Methods
Kim S, Lee K
Neuropsychiatric Disease and Treatment 2021, 17:3415-3430
Published Date: 20 November 2021

Identification of Bonding Difficulties in the Peripartum Period Using the Mother-to-Infant Bonding Scale-Japanese Version and Its Tentative Cutoff Points
Hashijiri K, Watanabe Y, Fukui N, Motegi T, Ogawa M, Egawa J, Enomoto T, Someya T
Neuropsychiatric Disease and Treatment 2021, 17:3407-3413
Published Date: 20 November 2021

Content Validation of an Algorithm for the Assessment, Management and Monitoring of Drug-Induced QTc Prolongation in the Psychiatric Population


Zolezzi M, Elhakim A, Elamin WM, Homs S, Mahmoud DE, Qubaiah IA
Neuropsychiatric Disease and Treatment 2021, 17:3395-3405
Published Date: 19 November 2021
Preliminary Findings on Visual Event-Related Potential P3 in Asymptomatic Patients with Cerebral Small Vessel Disease
Nie S, Shen C, Guo Y, Hou X, Hong Y, Xu S, Lv R, Liu X
Neuropsychiatric Disease and Treatment 2021, 17:3379-3394
Published Date: 18 November 2021

Preventive Approaches for Post-Stroke Depression: Where Do We Stand? A Systematic Review
Woranush W, Moskopp ML, Sedghi A, Stuckart I, Noll T, Barlinn K, Siepmann T
Neuropsychiatric Disease and Treatment 2021, 17:3359-3377
Published Date: 19 November 2021

Dopamine and Neuroinflammation in Schizophrenia – Interpreting the Findings from Translocator Protein (18kDa) PET Imaging
Iliopoulou SM, Tsartsalis S, Kaiser S, Millet P, Tournier BB
Neuropsychiatric Disease and Treatment 2021, 17:3345-3357
Published Date: 18 November 2021

The Role of Acupuncture in Treating Perimenopausal Insomnia: An Overview and Quality Assessment of Systematic Reviews and Meta-Analyses
Zhao FY, Zhang WJ, Kennedy GA, Conduit R, Zheng Z, Fu QQ
Neuropsychiatric Disease and Treatment 2021, 17:3325-3343
Published Date: 11 November 2021

Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia
Tanifuji T, Okazaki S, Otsuka I, Horai T, Shinko Y, Kim S, Sora I, Hishimoto A
Neuropsychiatric Disease and Treatment 2021, 17:3315-3323
Published Date: 11 November 2021
Proteomic Analysis Reveals that Di Dang Decoction Protects Against Acute Intracerebral Hemorrhage Stroke in Rats by Regulating S100a8, S100a9 Col1a1, and Col1a2
Feng L, Li M, Ren J, Li Y, Wang Q, Zhang P, Zhang X, Wang T, Li Y
Neuropsychiatric Disease and Treatment 2021, 17:3301-3314
Published Date: 10 November 2021

Not All Cases of Visual Snows are Benign: Mimics of Visual Snow Syndrome
Hang C, Leishangthem L, Yan Y
Neuropsychiatric Disease and Treatment 2021, 17:3293-3300
Published Date: 10 November 2021

Association of Conflict-Affected Environment on Ethiopian Students’ Mental Health and Its Correlates During COVID-19 Era
Madoro D, Mengistu N, Molla W
Neuropsychiatric Disease and Treatment 2021, 17:3283-3292
Published Date: 6 November 2021

Retinal Imaging Techniques Based on Machine Learning Models in Recognition and Prediction of Mild Cognitive Impairment
Zhang Q, Li J, Bian M, He Q, Shen Y, Lan Y, Huang D
Neuropsychiatric Disease and Treatment 2021, 17:3267-3281
Published Date: 6 November 2021

Acupuncture Treatment is Associated with a Decreased Risk of Dementia in Patients with Depression: A Propensity Score-Matched Cohort Study
Chen KY, Huang MC, Lin CL, Lee YC, Wu MY, Yen HR
Neuropsychiatric Disease and Treatment 2021, 17:3255-3266
Published Date: 4 November 2021
High Serum S100A12 Levels Predict Poor Outcome After Acute Primary Intracerebral Hemorrhage
Qiu SZ, Zheng GR, Ma CY, Chen B, Huang JJ, Huang G, Hua H
Neuropsychiatric Disease and Treatment 2021, 17:3245-3253
Published Date: 2 November 2021

Factors That Affect Patient Attrition in Buprenorphine Treatment for Opioid Use Disorder: A Retrospective Real-World Study Using Electronic Health Records
Ker S, Hsu J, Balani A, Mukherjee SS, Rush AJ, Khan M, Elchehabi S, Huffhines S, DeMoss D, Rentería ME, Sarkar J
Neuropsychiatric Disease and Treatment 2021, 17:3229-3244
Published Date: 28 October 2021

Treatment Goals in Schizophrenia: A Real-World Survey of Patients, Psychiatrists, and Caregivers in the United States, with an Analysis of Current Treatment (Long-Acting Injectable vs Oral Antipsychotics) and Goal Selection
Fitzgerald HM, Shepherd J, Bailey H, Berry M, Wright J, Chen M
Neuropsychiatric Disease and Treatment 2021, 17:3215-3228
Published Date: 21 October 2021
Treatment Strategies for Cryptogenic Stroke Patients with Patent Foramen Ovale: What Do We Choose?
Shen Y, Nie Q, Zhang Y, Cao Q, Hou Z, Xu L
Neuropsychiatric Disease and Treatment 2021, 17:3205-3214
Published Date: 22 October 2021
Association Between Lack of Insight and Prefrontal Serotonin Transporter Availability in Antipsychotic-Free Patients with Schizophrenia: A High-Resolution PET Study with [11C]DASB
Kim JH, Son YD, Kim HK, Kim JH
Neuropsychiatric Disease and Treatment 2021, 17:3195-3203
Published Date: 21 October 2021

Herbal Medicine for Patients with Cognitive Impairment: An Observational Study
Choi Y, Kim AR, Lee JY, Kim HS, Yang C, Kim JK, Go Y, Jung IC
Neuropsychiatric Disease and Treatment 2021, 17:3183-3194
Published Date: 21 October 2021

Victimization in Childhood Mediates the Association Between Parenting Quality, Stressful Life Events, and Depression in Adulthood
Ishii Y, Masuya J, Morishita C, Higashiyama M, Inoue T, Ichiki M
Neuropsychiatric Disease and Treatment 2021, 17:3171-3182
Published Date: 19 October 2021
Transitioning from Once-Monthly to Once-Every-3-Months Paliperidone Palmitate Among Veterans with Schizophrenia
El Khoury AC, Patel C, Mavros P, Huang A, Wang L, Bashyal R
Neuropsychiatric Disease and Treatment 2021, 17:3159-3170
Published Date: 19 October 2021
Inhibition of miR-448-3p Attenuates Cerebral Ischemic Injury by Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)
Xu M, Xiang D, Wang W, Chen L, Lu W, Cheng F
Neuropsychiatric Disease and Treatment 2021, 17:3147-3158
Published Date: 19 October 2021
Comparison of Persistence and Adherence Between Adults Diagnosed with Attention Deficit/Hyperactivity Disorder in Childhood and Adulthood
Lee SM, Cheong HK, Oh IH, Hong M
Neuropsychiatric Disease and Treatment 2021, 17:3137-3146
Published Date: 15 October 2021

An Evidence-Based Review of OLZ/SAM for Treatment of Adults with Schizophrenia or Bipolar I Disorder [Corrigendum]
Citrome L, Graham C, Simmons A, Jiang Y, Todtenkopf MS, Silverman B, DiPetrillo L, Cummings H, Sun L, McDonnell D
Neuropsychiatric Disease and Treatment 2021, 17:3135-3136
Published Date: 15 October 2021

Tardive Dyskinesia in Older Persons Taking Antipsychotics
Citrome L, Isaacson SH, Larson D, Kremens D
Neuropsychiatric Disease and Treatment 2021, 17:3127-3134
Published Date: 14 October 2021
Effectiveness and Safety of Pressure Dressings on Reducing Subdural Effusion After Decompressive Craniectomy
Huang W, Zhou B, Li Y, Shao Y, Peng B, Jiang X, Xiang T
Neuropsychiatric Disease and Treatment 2021, 17:3119-3125
Published Date: 14 October 2021
Association Between the A118G Polymorphism of the OPRM1 Gene and Suicidal Depression in a Large Cohort of Outpatients with Depression
Nobile B, Olie E, Ramoz N, Dubois J, Guillaume S, Gorwood P, Courtet P
Neuropsychiatric Disease and Treatment 2021, 17:3109-3118
Published Date: 14 October 2021

Change in Antidepressant Use After Initiation of ADHD Medication in Japanese Adults with Comorbid Depression: A Real-World Database Analysis
Sakai C, Tsuji T, Nakai T, Namba Y, Mishima H, Fujiwara M, Matsunaga H
Neuropsychiatric Disease and Treatment 2021, 17:3097-3108
Published Date: 11 October 2021

Can Goal-Based Health Management Improve the Health Knowledge, Health Belief and Health Behavior in People at High Risk of Stroke? A Non-Randomized Controlled Trial


He Y, Guo L, Liu Y, Wei M, Guo Y, Dong X, Yang C, Zhou Q, Lei X, Zhang G, Zhang M
Neuropsychiatric Disease and Treatment 2021, 17:3085-3095
Published Date: 8 October 2021
Methylation of the RIN3 Promoter is Associated with Transient Ischemic Stroke/Mild Ischemic Stroke with Early Cognitive Impairment [Corrigendum]
Miao M, Yuan F, Ma X, Yang H, Gao X, Zhu Z, Bi J
Neuropsychiatric Disease and Treatment 2021, 17:3081-3083
Published Date: 7 October 2021
The Prognostic Impact of Susceptibility-Weighted Imaging Prominent Veins in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
Lu P, Cui L, Zhao X
Neuropsychiatric Disease and Treatment 2021, 17:3069-3079
Published Date: 7 October 2021
Improving Collateral Circulation: A Potential Adjunctive Strategy to Prevent or Slow the Progression of Vascular Dementia
Wei B, Wang Z, Wu S, Orgah J, Zhu J, Song W
Neuropsychiatric Disease and Treatment 2021, 17:3061-3067
Published Date: 5 October 2021
Inflammatory Response in SARS-CoV-2 Infection of Patients with Schizophrenia and Long-Term Antipsychotic Treatment
Moga S, Teodorescu A, Ifteni P, Gavris C, Petric PS
Neuropsychiatric Disease and Treatment 2021, 17:3053-3060
Published Date: 2 October 2021

Comparison of Residual Depressive Symptoms, Functioning, and Quality of Life Between Patients with Recurrent Depression and First Episode Depression After Acute Treatment in China
Zu S, Wang D, Fang J, Xiao L, Zhu X, Wu W, Wang G, Hu Y
Neuropsychiatric Disease and Treatment 2021, 17:3039-3051
Published Date: 1 October 2021

Parents of Children Diagnosed with Autism Spectrum Disorder: What Do They Expect and Experience from Preschools?
Westman Andersson G, Gillberg N, Miniscalco C
Neuropsychiatric Disease and Treatment 2021, 17:3025-3037
Published Date: 28 September 2021
Reduced Brain Activation in Response to Social Cognition Tasks in Autism Spectrum Disorder with and without Depression
Ohtani T, Matsuo K, Sutoh C, Oshima F, Hirano Y, Wakabayashi A, Shimizu E
Neuropsychiatric Disease and Treatment 2021, 17:3015-3024
Published Date: 28 September 2021

Impact of the COVID-19 Pandemic on Family Wellbeing in the Context of Neurodevelopmental Disorders
Rizzo R, Karlov L, Maugeri N, di silvestre S, Eapen V
Neuropsychiatric Disease and Treatment 2021, 17:3007-3014
Published Date: 24 September 2021

Patient Expectations and Experiences of Antidepressant Therapy for Major Depressive Disorder: A Qualitative Study
Baune BT, Florea I, Ebert B, Touya M, Ettrup A, Hadi M, Ren H
Neuropsychiatric Disease and Treatment 2021, 17:2995-3006
Published Date: 23 September 2021
The Association Between Hypoxia Improvement and Electroconvulsive Therapy for Major Depressive Disorder
Bian Z, Li H, Liu Y, Cao Y, Kang Y, Yu Y, Zhang F, Li C, Kang Y, Wang F
Neuropsychiatric Disease and Treatment 2021, 17:2987-2994
Published Date: 22 September 2021

Current Perspectives on the Assessment and Management of Gait Disorders in Parkinson’s Disease
Smith MD, Brazier DE, Henderson EJ
Neuropsychiatric Disease and Treatment 2021, 17:2965-2985
Published Date: 21 September 2021
Severity of Depressive Symptoms is Associated with Venous Thromboembolism in Hospitalized Patients with a Major Depressive Episode
Yoshizawa K, Takeshima M, Ishino S, Ogasawara M, Fujiwara D, Itoh Y, Imanishi A, Ohta H, Mishima K
Neuropsychiatric Disease and Treatment 2021, 17:2955-2963
Published Date: 21 September 2021

Optimal Method of Electrical Stimulation for the Treatment of Upper Limb Dysfunction After Stroke: A Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials
Tang Y, Wang L, He J, Xu Y, Huang S, Fang Y
Neuropsychiatric Disease and Treatment 2021, 17:2937-2954
Published Date: 15 September 2021

Association Between ZNF804A Gene rs1344706 Polymorphism and Brain Functions in Healthy Individuals: A Systematic Review and Voxel-Based Meta-Analysis
Yang L, Xu F, He Y, Li Y, Chen Z, Wang S
Neuropsychiatric Disease and Treatment 2021, 17:2925-2935
Published Date: 14 September 2021

Patient and Physician Perspectives of Depressive Symptoms and Expectations for Treatment Outcome: Results from a Web-Based Survey
Ishigooka J, Hoshino T, Imai T, Yoshida H, Ono M, Ota M, Moriguchi Y, Fujikawa K, Shintani A, Fernandez JL
Neuropsychiatric Disease and Treatment 2021, 17:2915-2924
Published Date: 10 September 2021
Risk Factors and Neurologic Outcomes in Patients with Traumatic Brain Injury and Coagulopathy Within 72 h After Surgery
Chang T, Yan X, Zhao C, Zhang Y, Wang B, Gao L
Neuropsychiatric Disease and Treatment 2021, 17:2905-2913
Published Date: 10 September 2021


An Evidence-Based Review of OLZ/SAM for Treatment of Adults with Schizophrenia or Bipolar I Disorder
Citrome L, Graham C, Simmons A, Jiang Y, Todtenkopf MS, Silverman B, DiPetrillo L, Cummings H, Sun L, McDonnell D
Neuropsychiatric Disease and Treatment 2021, 17:2885-2904
Published Date: 9 September 2021
Association Between Anxious Symptom Severity and Olfactory Impairment in Young Adults with Generalized Anxiety Disorder: A Case–Control Study
Chen X, Guo W, Yu L, Luo D, Xie L, Xu J
Neuropsychiatric Disease and Treatment 2021, 17:2877-2883
Published Date: 7 September 2021

Relationship Between Mood Episode and Employment Status of Outpatients with Bipolar Disorder: Retrospective Cohort Study from the Multicenter Treatment Survey for Bipolar Disorder in Psychiatric Clinics (MUSUBI) Project
Konno Y, Fujino Y, Ikenouchi A, Adachi N, Kubota Y, Azekawa T, Ueda H, Edagawa K, Katsumoto E, Goto E, Hongo S, Kato M, Tsuboi T, Yasui-Furukori N, Nakagawa A, Kikuchi T, Watanabe K, Yoshimura R
Neuropsychiatric Disease and Treatment 2021, 17:2867-2876
Published Date: 7 September 2021

Effect of Low Complement C4 on Clinical Characteristics of Patients with First-Episode Neuromyelitis Optica Spectrum Disorder
Pan C, Zhao Y, Xie H, Zhou Y, Duan R, Li Y, Jia Y, Peng T
Neuropsychiatric Disease and Treatment 2021, 17:2859-2866
Published Date: 7 September 2021
A Cross-Sectional Analysis of the Prevalence and Determinants of Mental Distress Among Ethiopian Returnees
Madoro D
Neuropsychiatric Disease and Treatment 2021, 17:2849-2857
Published Date: 30 August 2021
Effects of Smartphone-Delivered Positive-Word Stimulation on Depressed Mood in People with Subthreshold Depression: Protocol for a Pilot Randomized Controlled Trial [Corrigendum]
Ejiri H, Uchida H, Tsuchiya K, Fujiwara K, Kikuchi S, Hirao K
Neuropsychiatric Disease and Treatment 2021, 17:2847-2848
Published Date: 30 August 2021

Prevalence of Symptoms of Anxiety Among Residents of Kabul During Pandemic of COVID-19: A Report from Capital of Afghanistan
Rasib AR, Nemat A, Azimi M, Zaki N, Sediqi MF, Raufi N, Asady A
Neuropsychiatric Disease and Treatment 2021, 17:2841-2846
Published Date: 29 August 2021
Mental Health Outcomes among Frontline Health-Care Workers at Eka Kotebe National COVID-19 Treatment Center, Addis Ababa, Ethiopia, 2020: A Cross-Sectional Study
Habtamu Y, Admasu K, Tullu M, Damene W, Birhanu A, Beyero T, Birhanu Tereda A
Neuropsychiatric Disease and Treatment 2021, 17:2831-2840
Published Date: 28 August 2021

The Combination of Serum BDNF, Cortisol and IFN-Gamma Can Assist the Diagnosis of Major Depressive Disorder
Chen S, Zhang Y, Yuan Y
Neuropsychiatric Disease and Treatment 2021, 17:2819-2829
Published Date: 26 August 2021
Research Progress on PATJ and Underlying Mechanisms Associated with Functional Outcomes After Stroke
Wang WJ, Lyu TJ, Li Z
Neuropsychiatric Disease and Treatment 2021, 17:2811-2818
Published Date: 26 August 2021
High Uric Acid Level Predicts Early Neurological Deterioration in Intracerebral Hemorrhage
Gong X, Lu Z, Feng X, Yuan K, Zhang M, Cheng X, Xue M, Yu L, Lu J, Yu C
Neuropsychiatric Disease and Treatment 2021, 17:2803-2809
Published Date: 24 August 2021
MiR-101 Protects Against the Cerebral I/R Injury Through Regulating JAK2/STAT3 Signaling Pathway
Guo X, Shen X, Yong Z
Neuropsychiatric Disease and Treatment 2021, 17:2791-2802
Published Date: 24 August 2021

Power Spectral Changes of Quantitative EEG in the Subjective Cognitive Decline: Comparison of Community Normal Control Groups
Jeong HT, Youn YC, Sung HH, Kim SY
Neuropsychiatric Disease and Treatment 2021, 17:2783-2790
Published Date: 24 August 2021

Associations Between Attention Deficit/Hyperactivity Disorder and Internet Gaming Disorder Symptoms Mediated by Depressive Symptoms and Hopelessness Among College Students
Chen C, Dai S, Shi L, Shen Y, Ou J
Neuropsychiatric Disease and Treatment 2021, 17:2775-2782
Published Date: 24 August 2021
CircRNA circPTK2 Might Suppress Cancer Cell Invasion and Migration of Glioblastoma by Inhibiting miR-23a Maturation
Chen W, Wang N, Lian M
Neuropsychiatric Disease and Treatment 2021, 17:2767-2774
Published Date: 21 August 2021

Interpersonal Sensitivity Mediates the Effects of Childhood Maltreatment on the Evaluation of Life Events and Anxiety States in Adult Community Volunteers
Nakazawa H, Masuya J, Tanabe H, Kusumi I, Inoue T, Ichiki M
Neuropsychiatric Disease and Treatment 2021, 17:2757-2766
Published Date: 20 August 2021
Serum Gamma-Glutamyltransferase Levels Predict the Development of Cerebral Infarction in the Korean Population
Lee SM, Ha E, Ryoo JH
Neuropsychiatric Disease and Treatment 2021, 17:2749-2756
Published Date: 20 August 2021
Effects of Smartphone-Delivered Positive-Word Stimulation on Depressed Mood in People with Subthreshold Depression: Protocol for a Pilot Randomized Controlled Trial
Ejiri H, Uchida H, Tsuchiya K, Fujiwara K, Kikuchi S, Hirao K
Neuropsychiatric Disease and Treatment 2021, 17:2739-2748
Published Date: 20 August 2021

Clinical Characteristics and Risk Factors of Cerebral Hemorrhage in Patients with Occult Malignant Tumors
Zhao Y, Xie H, Pan C, Yao Y, Gong Z, Li Y, Jia Y
Neuropsychiatric Disease and Treatment 2021, 17:2729-2738
Published Date: 19 August 2021

Myxedema Psychosis: Systematic Review and Pooled Analysis
Mohamed MFH, Danjuma M, Mohammed M, Mohamed S, Siepmann M, Barlinn K, Suwileh S, Abdalla L, Al-Mohanadi D, Silva Godínez JC, Elzouki AN, Siepmann T
Neuropsychiatric Disease and Treatment 2021, 17:2713-2728
Published Date: 18 August 2021
Efficacy of Repetitive Transcranial Magnetic Stimulation Combined with Botulinum Toxin Type A for Benign Essential Blepharospasm Patients Accompanied by Anxiety and Depression
Yin B, Peng B, Luo Y, Fan S, Xiao T, Zou X, Dong H
Neuropsychiatric Disease and Treatment 2021, 17:2707-2711
Published Date: 17 August 2021


Regional Neural Activity Changes in Parkinson’s Disease-Associated Mild Cognitive Impairment and Cognitively Normal Patients
Xing Y, Fu S, Li M, Ma X, Liu M, Liu X, Huang Y, Xu G, Jiao Y, Wu H, Jiang G, Tian J
Neuropsychiatric Disease and Treatment 2021, 17:2697-2706
Published Date: 17 August 2021

Safety and Effectiveness of Lurasidone in Patients with Schizophrenia: A 12-Week, Open-Label Extension Study
Iyo M, Ishigooka J, Nakamura M, Sakaguchi R, Okamoto K, Mao Y, Tsai J, Fitzgerald A, Takai K, Higuchi T
Neuropsychiatric Disease and Treatment 2021, 17:2683-2695
Published Date: 16 August 2021
Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression
Zhang L, Zhang L, Sui R
Neuropsychiatric Disease and Treatment 2021, 17:2671-2681
Published Date: 14 August 2021
Inhibition of NOD1 Attenuates Neonatal Hypoxia-Ischemia Induced Long-Term Cognitive Impairments in Mice Through Modulation of Autophagy-Related Proteins
Liu F, Shao M, Xu F, Rong F
Neuropsychiatric Disease and Treatment 2021, 17:2659-2669
Published Date: 14 August 2021

Correlations Between Working Memory Impairment and Neurometabolites of the Prefrontal Cortex in Drug-Naive Obsessive-Compulsive Disorder
Yue J, Zhong S, Luo A, Lai S, He T, Luo Y, Wang Y, Zhang Y, Shen S, Huang H, Wen S, Jia Y
Neuropsychiatric Disease and Treatment 2021, 17:2647-2657
Published Date: 14 August 2021

Intravenous Ketamine Infusions in Treatment-Resistant Bipolar Depression: An Open-Label Naturalistic Observational Study
Wilkowska A, Włodarczyk A, Gałuszko-Węgielnik M, Wiglusz MS, Cubała WJ
Neuropsychiatric Disease and Treatment 2021, 17:2637-2646
Published Date: 14 August 2021
Association of Childbirth Pain with Postnatal Depressive and Anxiety Disorders in Nulliparous Parturients: A Prospective Study
Tan CW, Tan HS, Sultana R, Chui A, Chua TE, Chen H, Sng BL
Neuropsychiatric Disease and Treatment 2021, 17:2625-2636
Published Date: 13 August 2021

Association Between NR4A2 Gene Polymorphism and Depressive Symptoms and Antidepressant Effect
Song X, Sun N, Zhang A, Lei L, Li X, Liu Z, Wang Y, Yang C, Zhang K
Neuropsychiatric Disease and Treatment 2021, 17:2613-2623
Published Date: 10 August 2021

Electroacupuncture Pretreatment Ameliorates Anesthesia and Surgery-Induced Cognitive Dysfunction via Activation of an α7-nAChR Signal in Aged Rats

Wang Z, Liu T, Yin C, Li Y, Gao F, Yu L, Wang Q
Neuropsychiatric Disease and Treatment 2021, 17:2599-2611
Published Date: 10 August 2021
Methylation of the RIN3 Promoter is Associated with Transient Ischemic Stroke/Mild Ischemic Stroke with Early Cognitive Impairment
Miao M, Yuan F, Ma X, Yang H, Gao X, Zhu Z, Bi J
Neuropsychiatric Disease and Treatment 2021, 17:2587-2598
Published Date: 10 August 2021

Associations of C-Reactive Protein, Free Triiodothyronine, Thyroid Stimulating Hormone and Creatinine Levels with Agitation in Patients with Schizophrenia: A Comparative Cross-Sectional Study
Li C, Shi Z, Ji J, Niu G, Liu Z
Neuropsychiatric Disease and Treatment 2021, 17:2575-2585
Published Date: 10 August 2021

Disability Status and Its Influencing Factors Among Stroke Patients in Northeast China: A 3-Year Follow-Up Study
Lv Y, Sun Q, Li J, Zhang W, He Y, Zhou Y
Neuropsychiatric Disease and Treatment 2021, 17:2567-2573
Published Date: 7 August 2021

Advances in the Treatment of Chronic Insomnia: A Narrative Review of New Nonpharmacologic and Pharmacologic Therapies
Rosenberg R, Citrome L, Drake CL
Neuropsychiatric Disease and Treatment 2021, 17:2549-2566
Published Date: 6 August 2021
Interaction of Insomnia and Somatization with Post-Traumatic Stress Disorder in Pregnant Women During the COVID-19 Pandemic
Zhang S, Zhou Y, Ge LK, Zeng L, Liu Z, Qian W, Yang J, Zhou X, Wei GX, Zhang X
Neuropsychiatric Disease and Treatment 2021, 17:2539-2547
Published Date: 6 August 2021

Change in the Frequency of Seizure Attacks and Associated Factors Among Adult Epilepsy Patients at Amanuel Mental Specialized Hospital (AMSH): A Generalized Linear Mixed Model (GLMM)
Raru TB, Geremew BM, Tamirat KS
Neuropsychiatric Disease and Treatment 2021, 17:2529-2538
Published Date: 4 August 2021
Maternal and Paternal Depression During Pregnancy in China: Prevalence, Correlates, and Network Analysis [Corrigendum]
Zhang Y, Sun H, Li W, Luo X, Liu T, Fang F, Xiao J, Garg S, Yang Y, Chen Y
Neuropsychiatric Disease and Treatment 2021, 17:2527-2528
Published Date: 3 August 2021

Early-Onset Schizophrenia: A Special Phenotype of the Disease Characterized by Increased MTHFR Polymorphisms and Aggravating Symptoms
Wan L, Wei J
Neuropsychiatric Disease and Treatment 2021, 17:2511-2525
Published Date: 3 August 2021
Impact of Antidepressants on Cardiac Events and All-Cause Mortality in Parkinson’s Disease: A National Data-Linkage Study
Orayj K
Neuropsychiatric Disease and Treatment 2021, 17:2499-2510
Published Date: 30 July 2021
Electroacupuncture Improves Cerebral Ischemic Injury by Enhancing the EPO-JAK2-STAT5 Pathway in Rats
Liu F, Lu Z, Li Z, Wang S, Zhuang L, Hong M, Huang K
Neuropsychiatric Disease and Treatment 2021, 17:2489-2498
Published Date: 30 July 2021
High Serum Levels of iNOS and MIP-1α are Associated with Post-Stroke Depression
Wang X, Fang C, Liu X, Wei W, Zhang M, Chen S, Shi F
Neuropsychiatric Disease and Treatment 2021, 17:2481-2487
Published Date: 28 July 2021

Nutrition Challenges of Patients with Alzheimer’s Disease and Related Dementias: A Qualitative Study from the Perspective of Caretakers in a Mental National Referral Hospital
Kigozi E, Egwela C, Kamoga L, Nalugo Mbalinda S, Kaddumukasa M
Neuropsychiatric Disease and Treatment 2021, 17:2473-2480
Published Date: 27 July 2021
Predictive Values of the SeLECT Score and IL-1β for Post-Stroke Epilepsy
Shen L, Yang J, Tang Y
Neuropsychiatric Disease and Treatment 2021, 17:2465-2472
Published Date: 27 July 2021

Social-Emotional Development and Associated Risk Factors in Chinese Toddlers with Cerebral Palsy
Wu Y, Tang J, Chen Y, Huang Y
Neuropsychiatric Disease and Treatment 2021, 17:2451-2463
Published Date: 24 July 2021

A Preliminary Randomized Controlled Trial of Different Treatment Regimens for Melancholic Depression
Wang Y, Liu X, Peng D, Wu Y, Su Y, Xu J, Ma X, Li Y, Shi J, Cheng X, Rong H, Fang Y
Neuropsychiatric Disease and Treatment 2021, 17:2441-2449
Published Date: 23 July 2021
Role of MT1A Polymorphism and Environmental Mercury Exposure on the Montreal Cognitive Assessment (MoCA)
Sirivarasai J, Chaisungnern K, Panpunuan P, Chanprasertyothin S, Chansirikanjana S, Sritara P
Neuropsychiatric Disease and Treatment 2021, 17:2429-2439
Published Date: 22 July 2021
Regional Ictal Hyperperfusion in the Contralateral Occipital Area May Be a Poor Prognostic Marker of Anterior Temporal Lobectomy: A SISCOM Analysis of MTLE Cases
Hwang Y, Lee HR, Jo H, Kim D, Joo EY, Seo DW, Hong SB, Shon YM
Neuropsychiatric Disease and Treatment 2021, 17:2421-2427
Published Date: 22 July 2021

Effect of Pharmacogenetic-Based Decision Support Tools in Improving Depression Outcomes: A Systematic Review
Aboelbaha S, Zolezzi M, Elewa H
Neuropsychiatric Disease and Treatment 2021, 17:2397-2419
Published Date: 21 July 2021
Psychometric Properties of the Chinese Version of the Clinically Useful Depression Outcome Scale for Patients with Major Depressive Disorder
Ma HY, Wang XM, Huang XJ, Yang CJ, Sheng DF, Yang JJ, Xu MZ
Neuropsychiatric Disease and Treatment 2021, 17:2387-2395
Published Date: 21 July 2021

A Case–Control Study on Behavioral Addictions and Neurocognition: Description of the BANCO and BANCO2 Protocols
Hurel E, Grall-Bronnec M, Thiabaud E, Saillard A, Hardouin JB, Challet-Bouju G
Neuropsychiatric Disease and Treatment 2021, 17:2369-2386
Published Date: 20 July 2021
Cerebroprotein Hydrolysate-I Inhibits Hippocampal Neuronal Apoptosis by Activating PI3K/Akt Signaling Pathway in Vascular Dementia Mice
Wu X, Liu Y, Zhu L, Wang Y, Ren Y, Cheng B, Ren L, Ge K, Li H
Neuropsychiatric Disease and Treatment 2021, 17:2359-2368
Published Date: 17 July 2021

Effect of Concomitant Benzodiazepine Use on Efficacy and Safety of Esketamine Nasal Spray in Patients with Major Depressive Disorder and Acute Suicidal Ideation or Behavior: Pooled Randomized, Controlled Trials
Diekamp B, Borentain S, Fu DJ, Murray R, Heerlein K, Zhang Q, Schüle C, Mathews M
Neuropsychiatric Disease and Treatment 2021, 17:2347-2357
Published Date: 15 July 2021


Clinically Significant Changes in the 17- and 6-Item Hamilton Rating Scales for Depression: A STAR*D Report
Rush AJ, South C, Jain S, Agha R, Zhang M, Shrestha S, Khan Z, Hassan M, Trivedi MH
Neuropsychiatric Disease and Treatment 2021, 17:2333-2345
Published Date: 14 July 2021


Cariprazine: Patients with Treatment-Resistant Schizophrenia
Aubel T
Neuropsychiatric Disease and Treatment 2021, 17:2327-2332
Published Date: 14 July 2021

Acupuncture Treatment Reduced the Risk of Coronary Heart Disease in Patients with Depression: A Propensity-Score Matched Cohort Study
Huang CY, Huang MC, Sun MF, Lin CL, Wu MY, Lin WC, Yen HR
Neuropsychiatric Disease and Treatment 2021, 17:2315-2325
Published Date: 12 July 2021


Epilepsy in Older People in Sub-Saharan Africa: A Systematic Review
Bongomin F, Katabira E, Sajatovic M, Kaddumukasa M
Neuropsychiatric Disease and Treatment 2021, 17:2309-2314
Published Date: 12 July 2021
Aβ Influx into the Blood Evoked by Different Blood Aβ Removal Systems: A Potential Therapy for Alzheimer’s Disease
Kitaguchi N, Kawaguchi K, Sakata M, Aoki H, Yamazaki K, Kaneko M, Kinomura J, Kato M, Hasegawa M, Suzuki N, Mizuno M, Yuzawa Y
Neuropsychiatric Disease and Treatment 2021, 17:2291-2308
Published Date: 13 July 2021
Clinical Evaluation of the Efficacy and Safety of Co-Administration of Wuzhi Capsule and Tacrolimus in Adult Chinese Patients with Myasthenia Gravis
Peng Y, Jiang F, Zhou R, Jin W, Li Y, Duan W, Xu L, Yang H
Neuropsychiatric Disease and Treatment 2021, 17:2281-2289
Published Date: 12 July 2021
Maternal and Paternal Depression During Pregnancy in China: Prevalence, Correlates, and Network Analysis
Zhang Y, Sun H, Li W, Luo X, Liu T, Fang F, Xiao J, Garg S, Yang Y, Chen Y
Neuropsychiatric Disease and Treatment 2021, 17:2269-2280
Published Date: 12 July 2021
Black Bamboo Rhizome Extract Improves Cognitive Dysfunction by Upregulating the Expression of Hippocampal BDNF and CREB in Rats with Cerebral Ischaemia-Reperfusion Injury
Yi CA, Jiang YH, Wang Y, Li YX, Cai SC, Wu XY, Hu XS, Wan XG
Neuropsychiatric Disease and Treatment 2021, 17:2257-2267
Published Date: 12 July 2021
Gastrodin Attenuates Tourette Syndrome by Regulating EAATs and NMDA Receptors in the Striatum of Rats
Sun X, Zhang X, Jiang K, Wu M
Neuropsychiatric Disease and Treatment 2021, 17:2243-2255
Published Date: 12 July 2021

Clinical Management of Drug Resistant Epilepsy: A Review on Current Strategies
Guery D, Rheims S
Neuropsychiatric Disease and Treatment 2021, 17:2229-2242
Published Date: 12 July 2021
Neuroprotective Function of TNFAIP3 Interacting Protein 2 Against Oxygen and Glucose Deprivation/Reoxygenation-Induced Injury in Hippocampal Neuronal HT22 Cells Through Regulation of the TLR4/MyD88/NF-κB Pathway
Yan Z, Chen Y, Zhang X, Hua L, Huang L
Neuropsychiatric Disease and Treatment 2021, 17:2219-2227
Published Date: 8 July 2021

Metacognitive Beliefs, Cognitive Functioning, Psychiatric Symptoms and Empathy in People with Schizophrenia
Chuang SP, Wu JYW, Wang CS
Neuropsychiatric Disease and Treatment 2021, 17:2209-2217
Published Date: 7 July 2021

The Cerebroprotein Hydrolysate-I Plays a Neuroprotective Effect on Cerebral Ischemic Stroke by Inhibiting MEK/ERK1/2 Signaling Pathway in Rats
Ren Y, Ma X, Wang T, Cheng B, Ren L, Dong Z, Liu H
Neuropsychiatric Disease and Treatment 2021, 17:2199-2208
Published Date: 6 July 2021

Relationship Between Serum Fibrinogen Level and Depressive Symptoms in an Adult Population with Spinal Cord Injury: A Cross-Sectional Study
Xie Z, Li C, Xing Z, Zhou W, Xie S, Li M, Zhou Y
Neuropsychiatric Disease and Treatment 2021, 17:2191-2198
Published Date: 6 July 2021
A Nomogram to Predict Symptomatic Intracranial Hemorrhage After Intravenous Thrombolysis in Chinese Patients
Guo H, Xu W, Zhang X, Zhang S, Dai Z, Li S, Xie Y, Li Y, Xue J, Liu X
Neuropsychiatric Disease and Treatment 2021, 17:2183-2190
Published Date: 6 July 2021

One in Five Street Traditional Coffee Vendors Suffered from Depression During the COVID-19 Pandemic in Harar Town, Ethiopia
Sisay M, Gashaw T, Degefu N, Hagos B, Alemu A, Teshome Z, Admas M, Kibret H, Dessie Y
Neuropsychiatric Disease and Treatment 2021, 17:2173-2182
Published Date: 6 July 2021

Differential Diagnosis in Children with Autistic Symptoms and Subthreshold ADOS Total Score: An Observational Study
De Giacomo A, Craig F, Palermo G, Coppola A, Margari M, Campanozzi S, Margari L, Turi M
Neuropsychiatric Disease and Treatment 2021, 17:2163-2172
Published Date: 5 July 2021

Repetitive Transcranial Magnetic Stimulation Improves Mild Cognitive Impairment Associated with Alzheimer’s Disease in Mice by Modulating the miR-567/NEUROD2/PSD95 Axis
Pang Y, Shi M
Neuropsychiatric Disease and Treatment 2021, 17:2151-2161
Published Date: 2 July 2021

Clozapine Management in Schizophrenia Inpatients: A 5-Year Prospective Observational Study of Its Safety and Tolerability Profile
de Filippis R, Gaetano R, Schoretsanitis G, Verde G, Oliveti CA, Kane JM, Segura-Garcia C, De Fazio P
Neuropsychiatric Disease and Treatment 2021, 17:2141-2150
Published Date: 1 July 2021

Milrinone Ameliorates the Neuroinflammation and Memory Function of Alzheimer’s Disease in an APP/PS1 Mouse Model
Chen Q, Yin Y, Li L, Zhang Y, He W, Shi Y
Neuropsychiatric Disease and Treatment 2021, 17:2129-2139
Published Date: 30 June 2021

Effect of 5-HT6 Receptor Ligands Combined with Haloperidol or Risperidone on Antidepressant-/Anxiolytic-Like Behavior and BDNF Regulation in Hippocampus and Prefrontal Cortex of Rats
Wesołowska A, Rychtyk J, Gdula-Argasińska J, Górecka K, Wilczyńska-Zawal N, Jastrzębska-Więsek M, Partyka A
Neuropsychiatric Disease and Treatment 2021, 17:2105-2127
Published Date: 25 June 2021
MicroRNA-126a-5p Exerts Neuroprotective Effects on Ischemic Stroke via Targeting NADPH Oxidase 2
Tan Y, Zhou F, Yang D, Zhang X, Zeng M, Wan L
Neuropsychiatric Disease and Treatment 2021, 17:2089-2103
Published Date: 25 June 2021

Long Non-Coding RNA GABPB1-AS1 Augments Malignancy of Glioma Cells by Sequestering MicroRNA-330 and Reinforcing the ZNF367/Cell Cycle Signaling Pathway
Li X, Wang H
Neuropsychiatric Disease and Treatment 2021, 17:2073-2087
Published Date: 10 July 2021

Physical and Mental Fatigue in Subjects Recovered from COVID-19 Infection: A Case–Control Study
Elanwar R, Hussein M, Magdy R, Eid RA, Yassien A, Abdelsattar AS, Alsharaway LA, Fathy W, Hassan A, Kamal YS
Neuropsychiatric Disease and Treatment 2021, 17:2063-2071
Published Date: 22 June 2021

Exploring Neural Mechanisms Related to Cognitive Control, Reward, and Affect in Eating Disorders: A Narrative Review of FMRI Studies
Wonderlich JA, Bershad M, Steinglass JE
Neuropsychiatric Disease and Treatment 2021, 17:2053-2062
Published Date: 21 June 2021

Clinical Characteristics, Iron Metabolism and Neuroinflammation: New Insight into Excessive Daytime Sleepiness in Parkinson’s Disease
Hu Y, Guo P, Lian TH, Zuo LJ, Yu SY, Liu L, Jin Z, Yu QJ, Wang RD, Li LX, Piao YS, Zhang W
Neuropsychiatric Disease and Treatment 2021, 17:2041-2051
Published Date: 21 June 2021
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis
Yang L, Pei L, Yi J
Neuropsychiatric Disease and Treatment 2021, 17:2027-2040
Published Date: 21 June 2021

Algorithms to Predict Anxiety and Depression Among University Students in China After Analyzing Lifestyles and Sport Habits
Zhang L, Zhao S, Lin Q, Song M, Wu S, Zheng H
Neuropsychiatric Disease and Treatment 2021, 17:2011-2025
Published Date: 21 June 2021

Association of Reduced Tract Integrity with Social Communication Deficits in Preschool Autism Children: A Tract-Based Spatial Statistics Study
Yin Y, Xu S, Li C, Li M, Liu M, Yan J, Lan Z, Zhan W, Jiang G, Tian J
Neuropsychiatric Disease and Treatment 2021, 17:2003-2010
Published Date: 18 June 2021
MicroRNA-9-3p Aggravates Cerebral Ischemia/Reperfusion Injury by Targeting Fibroblast Growth Factor 19 (FGF19) to Inactivate GSK-3β/Nrf2/ARE Signaling
Zhou Y, Yang L, Bo C, Zhang X, Zhang J, Li Y
Neuropsychiatric Disease and Treatment 2021, 17:1989-2002
Published Date: 18 June 2021
A Clinical Observation of Intravenous Thrombolysis in Acute Ischemic Stroke with Minor Trauma
Cui Y, Wang L
Neuropsychiatric Disease and Treatment 2021, 17:1983-1987
Published Date: 17 June 2021
Decreased Serum Total Bilirubin Level Predicts Early Neurological Deterioration in Patients with Acute Ischemic Stroke
Sheng X, Du H, Tang Y
Neuropsychiatric Disease and Treatment 2021, 17:1977-1982
Published Date: 17 June 2021

Do Teachers Confirm Parent’s Ratings of ADHD DSM-IV Criteria? A Study of a Mexican Population
Chamorro Y, Bolaños L, Trejo S, Barrios O, Ramírez-Dueñas ML, Alvarez-Tostado P, Cervantes A, Matute E
Neuropsychiatric Disease and Treatment 2021, 17:1965-1975
Published Date: 16 June 2021
Visualizing Patterns of Medication Switching Among Major Depressive Patients with Various Stability and Difficulty to Treatments
Hung YC, Chen HC, Kuo PH, Lu ML, Huang MC, Chen CH, Wang S, Mao WC, Wu CS, Wu TH
Neuropsychiatric Disease and Treatment 2021, 17:1953-1963
Published Date: 16 June 2021

ShenmaYizhi Decoction Improves the Mitochondrial Structure in the Brain and Ameliorates Cognitive Impairment in VCI Rats via the AMPK/UCP2 Signaling Pathway
Sun C, Liu M, Liu J, Zhang T, Zhang L, Li H, Luo Z
Neuropsychiatric Disease and Treatment 2021, 17:1937-1951
Published Date: 16 June 2021

Different Attitudes of Patients and Psychiatrists Toward Benzodiazepine Treatment
Kawamata Y, Sugawara N, Ishioka M, Kubo K, Suzuki K, Fujii A, Furukori H, Nakagami T, Yasui-Furukori N, Shimoda K
Neuropsychiatric Disease and Treatment 2021, 17:1927-1936
Published Date: 15 June 2021

Long-Acting Injectable Antipsychotics: A Systematic Review of Their Non-Systemic Adverse Effect Profile
Zolezzi M, Abouelhassan R, Eltorki Y, Haddad PM, Noorizadeh M
Neuropsychiatric Disease and Treatment 2021, 17:1917-1926
Published Date: 14 June 2021

Differences in the Association of Anxiety, Insomnia and Somatic Symptoms between Medical Staff and the General Population During the Outbreak of COVID-19
Huang Y, Zhou Y, Wei Y, Zeng L, Yang J, Li Y, Song X, Li H, He H, Li T, Wu K, Yang M, Wu F, Ning Y, Zhang X
Neuropsychiatric Disease and Treatment 2021, 17:1907-1915
Published Date: 14 June 2021
Cortical Pathways or Mechanism in the Face Inversion Effect in Patients with First-Episode Schizophrenia
Liu Y, Bi T, Kuang Q, Zhang B, Wu H, Li H, Zhang B, Zhao J, Ning Y, She S, Zheng Y
Neuropsychiatric Disease and Treatment 2021, 17:1893-1906
Published Date: 10 June 2021

Online Survey of Clinical Practice in Patients with Schizophrenia Treated with Long-Acting Injectable Aripiprazole or Paliperidone Palmitate
Such P, Olivares JM, Arias L, Troels Berg M, Madera J
Neuropsychiatric Disease and Treatment 2021, 17:1881-1892
Published Date: 10 June 2021
Eye Avoidance of Threatening Facial Expressions in Parents of Children with ASD
Yang T, Li D, Zhang Y, Zhang L, Li H, Ji GJ, Yang Z, Zhang L, Zhu C, Wang K
Neuropsychiatric Disease and Treatment 2021, 17:1869-1879
Published Date: 9 June 2021
Met and Unmet Needs in an Inpatient Psychiatry Setting in Spain
Gomez-Sanchez-Lafuente C, Guzman-Parra J, Lopez-Zambrano MA, Moreno-Kustner B, Mayoral-Cleries F
Neuropsychiatric Disease and Treatment 2021, 17:1859-1868
Published Date: 8 June 2021

Periventricular White Matter Hyperintensity in Males is Associated with Post-Stroke Depression Onset at 3 Months
Tu XQ, Lai ZH, Zhang Y, Ding KQ, Ma FY, Yang GY, He JR, Zeng LL
Neuropsychiatric Disease and Treatment 2021, 17:1839-1857
Published Date: 8 June 2021

Updated Review on the Diagnosis and Primary Management of Psychogenic Nonepileptic Seizure Disorders
Lanzillotti AI, Sarudiansky M, Lombardi NR, Korman GP, D´Alessio L
Neuropsychiatric Disease and Treatment 2021, 17:1825-1838
Published Date: 4 June 2021
Ameliorative Effect of Parishin C Against Cerebral Ischemia-Induced Brain Tissue Injury by Reducing Oxidative Stress and Inflammatory Responses in Rat Model
Wang T, Chen H, Xia S, Chen X, Sun H, Xu Z
Neuropsychiatric Disease and Treatment 2021, 17:1811-1823
Published Date: 4 June 2021

Alcohol Use Disorder and Its Associate Factors Relating to Patients with Severe Mental Disorders Attending Psychiatric Follow-Ups in Northwest Ethiopia
Kassew T, Kiflie M, Minichil W, Dejen Tilahun A, Liyew B
Neuropsychiatric Disease and Treatment 2021, 17:1801-1810
Published Date: 4 June 2021
LncRNA SAMMSON Overexpression Suppresses Vascular Smooth Muscle Cell Proliferation via Inhibiting miR-130a Maturation to Participate in Intracranial Aneurysm
Pan W, Gao Y, Wan W, Xiao W, You C
Neuropsychiatric Disease and Treatment 2021, 17:1793-1799
Published Date: 4 June 2021
Neuroprotective Effects and Related Mechanisms of Echinacoside in MPTP-Induced PD Mice
Zhang ZN, Hui Z, Chen C, Liang Y, Tang LL, Wang SL, Xu CC, Yang H, Zhang JS, Zhao Y
Neuropsychiatric Disease and Treatment 2021, 17:1779-1792
Published Date: 3 June 2021

Psychiatric Emergencies During the Covid-19 Pandemic: A 6-Month Observational Study
Di Lorenzo R, Frattini N, Dragone D, Farina R, Luisi F, Ferrari S, Bandiera G, Rovesti S, Ferri P
Neuropsychiatric Disease and Treatment 2021, 17:1763-1778
Published Date: 3 June 2021

The Effect of Viloxazine Extended-Release Capsules on Functional Impairments Associated with Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents in Four Phase 3 Placebo-Controlled Trials
Nasser A, Hull JT, Liranso T, Busse GD, Melyan Z, Childress AC, Lopez FA, Rubin J
Neuropsychiatric Disease and Treatment 2021, 17:1751-1762
Published Date: 3 June 2021

The Value of Susceptibility-Weighted Imaging (SWI) in Evaluating the Ischemic Penumbra of Patients with Acute Cerebral Ischemic Stroke
Wang YR, Li ZS, Huang W, Yang HQ, Gao B, Chen YT
Neuropsychiatric Disease and Treatment 2021, 17:1745-1750
Published Date: 3 June 2021
Combined Effects of Mother’s, Father’s and Teacher’s Psychological Distress on Schoolchildren’s Mental Health Symptoms
Li S, Na J, Mu H, Li Y, Liu L, Zhang R, Sun J, Li Y, Sun W, Pan G, Yan L
Neuropsychiatric Disease and Treatment 2021, 17:1735-1743
Published Date: 3 June 2021
Migraine and Autism Spectrum Disorder: A Shared Hereditary Basis [Letter]
Sahito AM
Neuropsychiatric Disease and Treatment 2021, 17:1733-1734
Published Date: 1 June 2021
High Mobility Group Box 1/Toll-like Receptor 4 Signaling Increases GABRB3 Expression in Alcohol Exposure
Sun G, Qi X, Wang W, Li X, Luo C, Bai S, Xu S, Zhong X, Huang C, Zhu X, Huang Z
Neuropsychiatric Disease and Treatment 2021, 17:1725-1732
Published Date: 1 June 2021
Role of Growth Hormone in Countering the Effects of Anxiety and Depression in Women Undergoing in-vitro Fertilization-Embryo Transfer [Letter]
Sahito AM
Neuropsychiatric Disease and Treatment 2021, 17:1723-1724
Published Date: 28 May 2021

Neurostimulation Methods in the Treatment of Depression: A Comparison of rTMS, tDCS, and Venlafaxine Using a Pooled Analysis of Two Studies
Hejzlar M, Novak T, Bares M
Neuropsychiatric Disease and Treatment 2021, 17:1713-1722
Published Date: 28 May 2021
Clinical Analysis of Bilateral Thalamic Infarction Caused by Percheron Artery Occlusion
Chen P, Hao MM, Chen Y, Zhang H, Wang Z, Zhao B, Xue Y, Chai Y, Huang YF, Zhu J
Neuropsychiatric Disease and Treatment 2021, 17:1707-1712
Published Date: 28 May 2021
Value of Combining of the NLR and the Fibrinogen Level for Predicting Stroke-Associated Pneumonia
Cheng W, Chen L, Yu H, Lu D, Yu R, Chen J
Neuropsychiatric Disease and Treatment 2021, 17:1697-1705
Published Date: 28 May 2021
Association Analyses of SNAP25, HNMT, FCHSD1, and DBH Single-Nucleotide Polymorphisms with Parkinson’s Disease in a Northern Chinese Population
Dai C, Zhang Y, Zhan X, Tian M, Pang H
Neuropsychiatric Disease and Treatment 2021, 17:1689-1695
Published Date: 27 May 2021

Social Inferences as Mediators of Wellbeing in Depression
Giurgi-Oncu C, Bredicean C, Frandeș M, Enătescu V, Papavă I, Riviș I, Ursoniu S
Neuropsychiatric Disease and Treatment 2021, 17:1679-1687
Published Date: 27 May 2021
LncRNA GAS5 Silencing Attenuates Oxygen-Glucose Deprivation/Reperfusion-Induced Injury in Brain Microvascular Endothelial Cells via miR-34b-3p-Dependent Regulation of EPHA4
Shen B, Wang L, Xu Y, Wang H, He S
Neuropsychiatric Disease and Treatment 2021, 17:1667-1678
Published Date: 26 May 2021
CSF TNF-α Levels Were Associated with Longitudinal Change in Brain Glucose Metabolism Among Non-Demented Older People
Fu P, Zhu B, Huang Y
Neuropsychiatric Disease and Treatment 2021, 17:1659-1666
Published Date: 26 May 2021

The Effects of Repetitive Transcranial Magnetic Stimulation Antidepressant Response on Cold Cognition: A Single-Arm Prospective Longitudinal Study
Hopman HJ, Choy HY, Ho WS, Lu H, Wong WHO, Chan SMS
Neuropsychiatric Disease and Treatment 2021, 17:1647-1658
Published Date: 26 May 2021


Eating Disorders and the Use of Cognitive Enhancers and Psychostimulants Among University Students: A Cross-Sectional Study
Damiri B, Safarini OA, Nazzal Z, Abuhassan A, Farhoud A, Ghanim N, Al Ali R, Suhail M, Qino M, Zamareh M, Thabaleh A, Zahran J
Neuropsychiatric Disease and Treatment 2021, 17:1633-1645
Published Date: 25 May 2021

Setting Measurement-Based Care in Motion: Practical Lessons in the Implementation and Integration of Measurement-Based Care in Psychiatry Clinical Practice
Martin-Cook K, Palmer L, Thornton L, Rush AJ, Tamminga CA, Ibrahim HM
Neuropsychiatric Disease and Treatment 2021, 17:1621-1631
Published Date: 25 May 2021

Transient Global Amnesia: Risk Factors, Imaging Features, and Prognosis
He S, Ye Z, Yang Q, Lin J, Chen X, Chen Z, Chen L
Neuropsychiatric Disease and Treatment 2021, 17:1611-1619
Published Date: 25 May 2021


Psychiatric Disorders of Neurocysticercosis: Narrative Review


El-Kady AM, Allemailem KS, Almatroudi A, Abler B, Elsayed M
Neuropsychiatric Disease and Treatment 2021, 17:1599-1610
Published Date: 25 May 2021

Assessment of the Impact of Tardive Dyskinesia in Clinical Practice: Consensus Panel Recommendations
Jackson R, Brams MN, Citrome L, Hoberg AR, Isaacson SH, Kane JM, Kumar R
Neuropsychiatric Disease and Treatment 2021, 17:1589-1597
Published Date: 24 May 2021
Phantom Limb Pain and Sensations in Chinese Malignant Tumor Amputees: A Retrospective Epidemiological Study
Jiang S, Zheng K, Wang W, Pei Y, Qiu E, Zhu G
Neuropsychiatric Disease and Treatment 2021, 17:1579-1587
Published Date: 21 May 2021

Suicidal Ideation and Its Associated Factors Among Patients with Major Depressive Disorder at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia
Basha EA, Mengistu BT, Engidaw NA, Wubetu AD, Haile AB
Neuropsychiatric Disease and Treatment 2021, 17:1571-1577
Published Date: 21 May 2021
Ventilation Adjustment in ECT During COVID-19: Voluntary Hyperventilation is an Effective Strategy
de Arriba-Arnau A, Dalmau Llitjos A, Soria V, Labad J, Menchón JM, Urretavizcaya M
Neuropsychiatric Disease and Treatment 2021, 17:1563-1569
Published Date: 20 May 2021

Covid-19 Pandemic-Related Stress and Coping Strategies Among Adults with Chronic Disease in Southwest Ethiopia
Girma A, Ayalew E, Mesafint G
Neuropsychiatric Disease and Treatment 2021, 17:1551-1561
Published Date: 20 May 2021

A Retrospective Study of the Effects of Psychotropic Drugs on Neuroendocrine Hormones in Patients with Bipolar Disorder
Zhao S, Zhang B, Sun X
Neuropsychiatric Disease and Treatment 2021, 17:1543-1550
Published Date: 20 May 2021
lncRNA-Associated Competitive Endogenous RNA Regulatory Network in an Aβ25-35-Induced AD Mouse Model Treated with Tripterygium Glycoside
Tang L, Xiang Q, Xiang J, Li J
Neuropsychiatric Disease and Treatment 2021, 17:1531-1541
Published Date: 19 May 2021

Prevalence and Correlates of Suicide Ideation and Attempt among Pregnant Women Attending Antenatal Care Services at Public Hospitals in Southern Ethiopia
Belete K, Kassew T, Demilew D, Amare Zeleke T
Neuropsychiatric Disease and Treatment 2021, 17:1517-1529
Published Date: 18 May 2021

Temporal Dynamics in Degree Centrality of Brain Functional Connectome in First-Episode Schizophrenia with Different Short-Term Treatment Responses: A Longitudinal Study
Wang Y, Jiang Y, Su W, Xu L, Wei Y, Tang Y, Zhang T, Tang X, Hu Y, Cui H, Wang J, Yao D, Luo C, Wang J
Neuropsychiatric Disease and Treatment 2021, 17:1505-1516
Published Date: 18 May 2021

Neutrophil-to-Lymphocyte Ratio on Admission is an Independent Risk Factor for the Severity of Neurological Impairment at Disease Onset in Patients with a First Episode of Neuromyelitis Optica Spectrum Disorder
Zhou Y, Xie H, Zhao Y, Zhang J, Li Y, Duan R, Yao Y, Jia Y
Neuropsychiatric Disease and Treatment 2021, 17:1493-1503
Published Date: 18 May 2021

Cognitive Impairment and Associated Factors Among Chronic Kidney Disease Patients: A Comparative Cross-Sectional Study
Gela YY, Getu AA, Adane A, Ayal BM, Akalu Y, Ambelu A, Diress M, Yeshaw Y
Neuropsychiatric Disease and Treatment 2021, 17:1483-1492
Published Date: 17 May 2021
Safety and Tolerability of Cariprazine in Patients with Schizophrenia: A Pooled Analysis of Eight Phase II/III Studies [Corrigendum]
Barabássy Á, Sebe B, Acsai K, Laszlovszky I, Szatmári B, Earley WR, Németh G
Neuropsychiatric Disease and Treatment 2021, 17:1481-1482
Published Date: 17 May 2021

Diagnostic Challenges in Outpatient Stroke: Stroke Chameleons and Atypical Stroke Syndromes
Wallace EJC, Liberman AL
Neuropsychiatric Disease and Treatment 2021, 17:1469-1480
Published Date: 13 May 2021

Efficacy and Safety of tDCS and tACS in Treatment of Major Depressive Disorder: A Randomized, Double-Blind, Factorial Placebo-Controlled Study Design
Huang Y, Shen L, Huang J, Xu X, Wang Y, Jin H
Neuropsychiatric Disease and Treatment 2021, 17:1459-1468
Published Date: 12 May 2021

Late-Onset Leukodystrophy Mimicking Hereditary Spastic Paraplegia without Diffuse Leukodystrophy on Neuroimaging
Zhang T, Yan C, Liu Y, Cao L, Ji K, Li D, Chi L, Zhao Y
Neuropsychiatric Disease and Treatment 2021, 17:1451-1458
Published Date: 12 May 2021

Association of CDKN2A/CDKN2B Gene Polymorphisms with Increased Susceptibility to Intracranial Aneurysm in a Chinese Han Population
Cui X, Xin WQ, Wang B, Zhao Y, Hou C, Cai S, Peng C, Wang Z, Li J, Huan L, Chen L, Yang X
Neuropsychiatric Disease and Treatment 2021, 17:1443-1449
Published Date: 12 May 2021
Reduced Synaptic Plasticity Contributes to Resistance Against Constant-Stimulus Electroconvulsive Treatment in a Rat Model of Stress-Induced Depression
Wu B, Guo Y, Deng J, Chen Q, Min S
Neuropsychiatric Disease and Treatment 2021, 17:1433-1442
Published Date: 11 May 2021
Interleukin-6 in Cerebrospinal Fluid Small Extracellular Vesicles as a Potential Biomarker for Prognosis of Aneurysmal Subarachnoid Haemorrhage
Yao Y, Fang X, Yuan J, Qin F, Yu T, Xia D, Li Z, Lai N
Neuropsychiatric Disease and Treatment 2021, 17:1423-1431
Published Date: 11 May 2021

Psychological Impact of COVID-19, Isolation, and Quarantine: A Cross-Sectional Study
Jassim G, Jameel M, Brennan E, Yusuf M, Hasan N, Alwatani Y
Neuropsychiatric Disease and Treatment 2021, 17:1413-1421
Published Date: 11 May 2021
Mechanism of Autophagy Regulation in MPTP-Induced PD Mice via the mTOR Signaling Pathway by Echinacoside
Zhang ZN, Hui Z, Chen C, Liang Y, Tang LL, Wang SL, Xu CC, Yang H, Zhao Y, Zhang JS
Neuropsychiatric Disease and Treatment 2021, 17:1397-1411
Published Date: 10 May 2021

Altered Temporal Dynamics of Brain Activity in Multiple-Frequency Bands in Non-Neuropsychiatric Systemic Lupus Erythematosus Patients with Inactive Disease
Chen L, Sun J, Wang Q, Hu L, Zhang Y, Ma H, Jia X, Yang X
Neuropsychiatric Disease and Treatment 2021, 17:1385-1395
Published Date: 7 May 2021

Mental Health Adverse Effects of COVID-19 Pandemic on Health Care Workers in North West Ethiopia: A Multicenter Cross-Sectional Study
Asnakew S, Amha H, Kassew T
Neuropsychiatric Disease and Treatment 2021, 17:1375-1384
Published Date: 7 May 2021

Self-Reported Symptoms of Depression, Anxiety, and Stress Among Healthcare Workers in Ethiopia During the COVID-19 Pandemic: A Cross-Sectional Study
Jemal K, Deriba BS, Geleta TA, Tesema M, Awol M, Mengistu E, Annous Y
Neuropsychiatric Disease and Treatment 2021, 17:1363-1373
Published Date: 6 May 2021

Depression and Related Factors in Patients with Parkinson’s Disease at High Altitude
Cao Y, Li G, Xue J, Zhang G, Gao S, Huang Y, Zhu A
Neuropsychiatric Disease and Treatment 2021, 17:1353-1362
Published Date: 6 May 2021

Current Challenges in the Recognition and Management of Delirium Superimposed on Dementia
Nitchingham A, Caplan GA
Neuropsychiatric Disease and Treatment 2021, 17:1341-1352
Published Date: 5 May 2021

Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer’s Disease
Fulop T, Tripathi S, Rodrigues S, Desroches M, Bunt T, Eiser A, Bernier F, Beauregard PB, Barron AE, Khalil A, Plotka A, Hirokawa K, Larbi A, Bocti C, Laurent B, Frost EH, Witkowski JM
Neuropsychiatric Disease and Treatment 2021, 17:1311-1339
Published Date: 4 May 2021

The Role of Cognitive Complaints in the Relationship Between Trait Anxiety, Depressive Symptoms, and Subjective Well-Being and Ill-Being in Adult Community Volunteers
Toyoshima K, Ichiki M, Inoue T, Masuya J, Fujimura Y, Higashi S, Kusumi I
Neuropsychiatric Disease and Treatment 2021, 17:1299-1309
Published Date: 30 April 2021

Association Between ApoA1 Gene Polymorphisms and Antipsychotic Drug-Induced Dyslipidemia in Schizophrenia
Fan L, You Y, Fan Y, Shen C, Xue Y
Neuropsychiatric Disease and Treatment 2021, 17:1289-1297
Published Date: 30 April 2021

Comparative Effects of Repetitive Odor Identification and Odor Memory Tasks on Olfactory Engagement in Older Populations – A Pilot fMRI Study
Rai N, Hipolito MM, VanMeter JW, Seth R, Adenuga A, Shelby M, Misiak-Christian M, Nwaokobia C, Manaye KF, Obisesan TO, Nwulia E
Neuropsychiatric Disease and Treatment 2021, 17:1279-1288
Published Date: 30 April 2021

Handgrip Strength and Depression Among Older Chinese Inpatients: A Cross-Sectional Study
Zhang XM, Jiao J, Cao J, Guo N, Zhu C, Li Z, Wu X, Xu T
Neuropsychiatric Disease and Treatment 2021, 17:1267-1277
Published Date: 30 April 2021

Challenges in the Diagnosis and Assessment in Patients with Tourette Syndrome and Comorbid Obsessive-Compulsive Disorder
Szejko N, Müller-Vahl KR
Neuropsychiatric Disease and Treatment 2021, 17:1253-1266
Published Date: 30 April 2021

Depressive-, Cognitive- or Stroke-Related Risk Factors of Post-Stroke Depression: Which One Could Better Help Clinicians and Patients?
Perrain R, Calvet D, Guiraud V, Mekaoui L, Mas JL, Gorwood P
Neuropsychiatric Disease and Treatment 2021, 17:1243-1251
Published Date: 29 April 2021
MiR-195-5p Ameliorates Cerebral Ischemia-Reperfusion Injury by Regulating the PTEN-AKT Signaling Pathway
Ren X, Wang Z, Guo C
Neuropsychiatric Disease and Treatment 2021, 17:1231-1242
Published Date: 29 April 2021
Letter to the Editor Regarding the Article, “Lithium in Late-Life Mania: A Systematic Review” [Letter]
Shah K, Mansuri Z, Jain S
Neuropsychiatric Disease and Treatment 2021, 17:1229-1230
Published Date: 28 April 2021
COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein
Liang E, Li X, Fu W, Zhao C, Yang B, Yang Z
Neuropsychiatric Disease and Treatment 2021, 17:1217-1227
Published Date: 22 April 2021

Altered Extended Locus Coeruleus and Ventral Tegmental Area Networks in Boys with Autism Spectrum Disorders: A Resting-State Functional Connectivity Study
Huang Y, Yu S, Wilson G, Park J, Cheng M, Kong X, Lu T, Kong J
Neuropsychiatric Disease and Treatment 2021, 17:1207-1216
Published Date: 22 April 2021

Clinical Characteristics and Management of Cerebral Venous Sinus Thrombosis in Patients with Essential Thrombocythemia
Jiao L, Huang X, Fan C, Zhao H, Li Z, Shen H, Chen J, Duan J
Neuropsychiatric Disease and Treatment 2021, 17:1195-1206
Published Date: 22 April 2021

Exploring the Hereditary Nature of Migraine
Bron C, Sutherland HG, Griffiths LR
Neuropsychiatric Disease and Treatment 2021, 17:1183-1194
Published Date: 22 April 2021

Biliverdin Protects Against Cerebral Ischemia/Reperfusion Injury by Regulating the miR-27a-3p/Rgs1 Axis
Li J, Peng L, Bai W, Peng P, Chen W, Yang W, Shao J
Neuropsychiatric Disease and Treatment 2021, 17:1165-1181
Published Date: 22 April 2021
Long Noncoding RNA SNHG1 Knockdown Ameliorates Apoptosis, Oxidative Stress and Inflammation in Models of Parkinson’s Disease by Inhibiting the miR-125b-5p/MAPK1 Axis
Xiao X, Tan Z, Jia M, Zhou X, Wu K, Ding Y, Li W
Neuropsychiatric Disease and Treatment 2021, 17:1153-1163
Published Date: 22 April 2021
Venlafaxine Inhibits the Apoptosis of SHSY-5Y Cells Through Active Wnt/β-Catenin Signaling Pathway
Geng R, Li H, Wang H, Ye C, Mao Y, Huang X
Neuropsychiatric Disease and Treatment 2021, 17:1145-1151
Published Date: 21 April 2021
Psychometric Properties of the Chinese Version of the Cognitions About Body and Health Questionnaire
Liao SC, Huang WL
Neuropsychiatric Disease and Treatment 2021, 17:1135-1144
Published Date: 21 April 2021
Association Analysis of Polymorphisms in BIN1, MC1R, STARD6 and PVRL2 with Mild Cognitive Impairment in Elderly Carrying APOE ϵ4 Allele
Wu Y, Yin J, Yang B, Tang L, Feng W, Liu X, Zhao X, Cheng Z
Neuropsychiatric Disease and Treatment 2021, 17:1125-1133
Published Date: 21 April 2021

Characteristics of TCM Constitution and Related Biomarkers for Mild Cognitive Impairment
Deng X, Teng J, Nong X, Yu B, Tang L, Liang J, Zou Z, Liu Q, Zhou L, Li Q, Zhao L
Neuropsychiatric Disease and Treatment 2021, 17:1115-1124
Published Date: 20 April 2021

Identifying Subjective Symptoms Associated with Psychomotor Disturbance in Melancholia: A Multiple Regression Analysis Study
Tamada Y, Inoue T, Sekine A, Toda H, Takeshima M, Sasaki M, Shindome K, Morita W, Kuyama N, Ohmae S
Neuropsychiatric Disease and Treatment 2021, 17:1105-1114
Published Date: 19 April 2021
Early Improvement of Psychiatric Symptoms with Long-Acting Injectable Antipsychotic Predicts Subsequent Social Functional Remission in Patients with Schizophrenia
Ohnishi T, Wakamatsu A, Kobayashi H
Neuropsychiatric Disease and Treatment 2021, 17:1095-1104
Published Date: 16 April 2021


Decline in Psychotic Symptoms in Addition to Cardiac and Metabolic Safety with Cariprazine After Poor Response to Previous Antipsychotic Treatments – A Series of Two Cases
Müller HHO, Moeller S
Neuropsychiatric Disease and Treatment 2021, 17:1089-1093
Published Date: 15 April 2021

Functional Connectivity During Visuospatial Processing in Schizophrenia: A Classification Study Using Lasso Regression
Potvin S, Giguère CÉ, Mendrek A
Neuropsychiatric Disease and Treatment 2021, 17:1077-1087
Published Date: 14 April 2021
Plasma Levels of Long-Acting Injectable Antipsychotics in Outpatient Care: A Retrospective Analysis
Hýža M, Šilhán P, Češková E, Skřont T, Kacířová I, Uřinovská R, Grundmann M
Neuropsychiatric Disease and Treatment 2021, 17:1069-1075
Published Date: 14 April 2021
Electroacupuncture Ameliorates Depressive-Like Behaviors in Poststroke Rats via Activating the tPA/BDNF/TrkB Pathway
Dong H, Qin YQ, Sun YC, Yao HJ, Cheng XK, Yu Y, Lu SS
Neuropsychiatric Disease and Treatment 2021, 17:1057-1067
Published Date: 13 April 2021
Letter to the Editor – Towards an Outpatient Model of Care for Motor Functional Neurological Disorders: A Neuropsychiatric Perspective [Letter]
de Vroege L, Vergeest A, Kop WJ
Neuropsychiatric Disease and Treatment 2021, 17:1055-1056
Published Date: 13 April 2021
Effect of Switching to Brexpiprazole on Plasma Homovanillic Acid Levels and Antipsychotic-Related Side Effects in Patients with Schizophrenia or Schizoaffective Disorder
Ichinose M, Miura I, Horikoshi S, Yamamoto S, Kanno-Nozaki K, Watanabe K, Yabe H
Neuropsychiatric Disease and Treatment 2021, 17:1047-1053
Published Date: 13 April 2021

Construct Validity and Differential Item Functioning of the PHQ-9 Among Health Care Workers: Rasch Analysis Approach
Jiraniramai S, Wongpakaran T, Angkurawaranon C, Jiraporncharoen W, Wongpakaran N
Neuropsychiatric Disease and Treatment 2021, 17:1035-1045
Published Date: 8 April 2021

Benzodiazepine and Z-Drug Use in Switzerland: Prevalence, Prescription Patterns and Association with Adverse Healthcare Outcomes
Landolt S, Rosemann T, Blozik E, Brüngger B, Huber CA
Neuropsychiatric Disease and Treatment 2021, 17:1021-1034
Published Date: 12 April 2021

Traditional Chinese Formula Xiaoyaosan Alleviates Depressive-Like Behavior in CUMS Mice by Regulating PEBP1-GPX4-Mediated Ferroptosis in the Hippocampus
Jiao H, Yang H, Yan Z, Chen J, Xu M, Jiang Y, Liu Y, Xue Z, Ma Q, Li X, Chen J
Neuropsychiatric Disease and Treatment 2021, 17:1001-1019
Published Date: 6 April 2021
Association Between Serum Uric Acid Levels and Cognitive Function in Patients with Ischemic Stroke and Transient Ischemic Attack (TIA): A 3-Month Follow-Up Study
Liu Q, Liao X, Pan Y, Jin A, Zhang Y
Neuropsychiatric Disease and Treatment 2021, 17:991-999
Published Date: 31 March 2021

A Systematic Review and Meta-Analysis of Transcranial Direct Current Stimulation to Remediate Age-Related Cognitive Decline in Healthy Older Adults
Indahlastari A, Hardcastle C, Albizu A, Alvarez-Alvarado S, Boutzoukas EM, Evangelista ND, Hausman HK, Kraft J, Langer K, Woods AJ
Neuropsychiatric Disease and Treatment 2021, 17:971-990
Published Date: 29 March 2021

Safety and Tolerability of Cariprazine in Patients with Schizophrenia: A Pooled Analysis of Eight Phase II/III Studies
Barabássy Á, Sebe B, Acsai K, Laszlovszky I, Szatmári B, Earley WR, Németh G
Neuropsychiatric Disease and Treatment 2021, 17:957-970
Published Date: 7 April 2021

Relationship of Subjective Cognitive Impairment with Psychosocial Function and Relapse of Depressive Symptoms in Patients with Major Depressive Disorder: Analysis of Longitudinal Data from PERFORM-J
Sumiyoshi T, Watanabe K, Noto S, Sakamoto S, Moriguchi Y, Hammer-Helmich L, Fernandez J
Neuropsychiatric Disease and Treatment 2021, 17:945-955
Published Date: 26 March 2021

Cognitive Impairment and Associated Factors Among Adult Hypothyroid Patients in Referral Hospitals, Amhara Region, Ethiopia: Multicenter Cross-Sectional Study
Mulat B, Ambelu A, Yitayih S, Gela YY, Adera A, Yeshaw Y, Akalu Y
Neuropsychiatric Disease and Treatment 2021, 17:935-943
Published Date: 25 March 2021
Urinary Metabolite Signatures for Predicting Elderly Stroke Survivors with Depression
Chen J, Lv Y, Li X, Xiong J, Liang H, Xie L, Wan C, Chen Y, Wang H, Liu P, Zheng H
Neuropsychiatric Disease and Treatment 2021, 17:925-933
Published Date: 25 March 2021

The Association of Insomnia with Depression and Anxiety Symptoms in Patients Undergoing Noncardiac Surgery
Huang X, Wu D, Wu AS, Wei CW, Gao JD
Neuropsychiatric Disease and Treatment 2021, 17:915-924
Published Date: 25 March 2021
Vagal Nerve Stimulation Protects Against Cerebral Ischemia–Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis
Zhang LN, Zhang XW, Li CQ, Guo J, Chen YP, Chen SL
Neuropsychiatric Disease and Treatment 2021, 17:905-913
Published Date: 25 March 2021

Psychometric Properties of the General Anxiety Disorders-7 Scale Using Categorical Data Methods: A Study in a Sample of University Attending Ethiopian Young Adults
Manzar MD, Alghadir AH, Anwer S, Alqahtani M, Salahuddin M, Addo HA, Jifar WW, Alasmee NA
Neuropsychiatric Disease and Treatment 2021, 17:893-903
Published Date: 22 March 2021

Assessment of Psychological Distress and Associated Factors among Hospitalized Patients During the COVID-19 Pandemic at Selected Hospitals in Southwest Ethiopia
Hambisa S, Siraj J, Mesafint G, Yimam M
Neuropsychiatric Disease and Treatment 2021, 17:885-892
Published Date: 22 March 2021

The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study
Wei X, Chen H, Guo C, Tan W, Zhan S
Neuropsychiatric Disease and Treatment 2021, 17:873-883
Published Date: 19 March 2021

Patterns of Migraine in Postmenopausal Women: A Systematic Review
Ornello R, Caponnetto V, Frattale I, Sacco S
Neuropsychiatric Disease and Treatment 2021, 17:859-871
Published Date: 19 March 2021

A Random Forest Model for Predicting Social Functional Improvement in Chinese Patients with Schizophrenia After 3 Months of Atypical Antipsychotic Monopharmacy: A Cohort Study
Li Y, Zhang L, Zhang Y, Wen H, Huang J, Shen Y, Li H
Neuropsychiatric Disease and Treatment 2021, 17:847-857
Published Date: 19 March 2021
Monocyte-to-Lymphocyte Ratio is Associated with Depression 3 Months After Stroke
Ding K, Lai Z, Zhang Y, Yang G, He J, Zeng L
Neuropsychiatric Disease and Treatment 2021, 17:835-845
Published Date: 19 March 2021

Real-World Treatment Patterns and Adherence to Oral Medication Among Patients with Bipolar Disorders: A Retrospective, Observational Study Using a Healthcare Claims Database
Inoue T, Sano H, Kojima Y, Yamada S, Shirakawa O
Neuropsychiatric Disease and Treatment 2021, 17:821-833
Published Date: 18 March 2021

The Relationship Between Type D Personality and the Complexity of Coronary Artery Disease
Enatescu VR, Cozma D, Tint D, Enatescu I, Simu M, Giurgi-Oncu C, Lazar MA, Mornos C
Neuropsychiatric Disease and Treatment 2021, 17:809-820
Published Date: 18 March 2021

A National Survey of Self-Prescription of Beta-Blockers and Their Relation to Undiscovered Anxiety Among Medical and Pharmacological Students in Saudi Arabia
Alsini A, Alkhodaidi I, Alsini Y, Alsseeni S, Alkhodaidi S, Alsini E, Alsini A, Sindi H, Alswat K
Neuropsychiatric Disease and Treatment 2021, 17:797-807
Published Date: 17 March 2021

Psychometric Properties of the Chinese Version of the Bipolar Depression Rating Scale for Bipolar Disorder
Chen JX, Yin L, Xu HT, Zhang SY, Huang WQ, Li HJ, Li BB, Yang KB, Li Q, Berk M, Su YA
Neuropsychiatric Disease and Treatment 2021, 17:787-795
Published Date: 12 March 2021
Effect of Comprehensive Nursing Based on Cognitive Behavior on Psychological Function of Glioma Patients
Zhao YH, Xu Y
Neuropsychiatric Disease and Treatment 2021, 17:777-785
Published Date: 10 March 2021

Recruitment Challenges for Studies of Deep Brain Stimulation for Treatment-Resistant Depression
Ramasubbu R, Golding S, Williams K, Mackie A, MacQueen G, Kiss ZHT
Neuropsychiatric Disease and Treatment 2021, 17:765-775
Published Date: 10 March 2021
Gray Matter Density of the Dorsomedial Prefrontal Cortex Mediates the Relationship Between Catastrophizing and Anxiety in Somatic Symptom Disorder
Pan X, Ding W, Sun X, Ji C, Zhou Q, Yan C, Zhou Y, Luo Y
Neuropsychiatric Disease and Treatment 2021, 17:757-764
Published Date: 9 March 2021
Taiwanese Depression Questionnaire and AD8 Questionnaire for Screening Late-Life Depression in Communities
Wei YC, Huang LY, Lin C, Shyu YC, Chen CK
Neuropsychiatric Disease and Treatment 2021, 17:747-755
Published Date: 9 March 2021
The Combination of Insulin Resistance and Serum Interleukin-1β Correlates with Post-Stroke Depression in Patients with Acute Ischemic Stroke
Yi X, Zhu X, Zhou Y, Zhang D, Li M, Zhu Y, Guo X
Neuropsychiatric Disease and Treatment 2021, 17:735-746
Published Date: 9 March 2021
Parkinson’s Disease-Associated Melanin Steal [Retraction]
Hinz M, Stein A, Cole T
Neuropsychiatric Disease and Treatment 2021, 17:733-734
Published Date: 3 March 2021
5-HTP Efficacy and Contraindications [Retraction]
Hinz M, Stein A, Uncini T
Neuropsychiatric Disease and Treatment 2021, 17:731-732
Published Date: 3 March 2021
Construction and Standardization of Dementia Arabic Scale
Farghaly WM, El Tallawy HN, Mohamed H, El Tallawy SH, Abdelhamed MA
Neuropsychiatric Disease and Treatment 2021, 17:721-729
Published Date: 3 March 2021

Short- and Long-Term Effects of Vitamin D Treatment on Bacillus Calmette-Guerin-Induced Depressive-Like Behavior in Mice
Saleh LA, Almutairi FM, Alorabi WK, Alkuhayli BA, Alzaidi SS, Alzahrani SB, Aljumayi FA, Abduljabbar MH, Alharthi AS, Alsufyani MA, Alhazmi MH, Althobaiti AA, Almutairi FN, Alshehri FS, Altowairqi E, Althobaiti YS
Neuropsychiatric Disease and Treatment 2021, 17:711-720
Published Date: 2 March 2021
Low-Protein, Hypocaloric Nutrition with Glutamine versus Full-Feeding in the Acute Phase in ICU Patients with Severe Traumatic Brain Injury
Xiong W, Qian K
Neuropsychiatric Disease and Treatment 2021, 17:703-710
Published Date: 2 March 2021

Early Post-Stroke Electroacupuncture Promotes Motor Function Recovery in Post-Ischemic Rats by Increasing the Blood and Brain Irisin
Liu L, Zhang Q, Li M, Wang N, Li C, Song D, Shen X, Luo L, Fan Y, Xie H, Wu Y
Neuropsychiatric Disease and Treatment 2021, 17:695-702
Published Date: 1 March 2021
P53/miR-154 Pathway Regulates the Epithelial-Mesenchymal Transition in Glioblastoma Multiforme Cells by Targeting TCF12
Zhu G, Yang S, Wang R, Lei J, Ji P, Wang J, Tao K, Yang C, Ge S, Wang L
Neuropsychiatric Disease and Treatment 2021, 17:681-693
Published Date: 26 February 2021
Dexmedetomidine Alleviates LPS-Induced Neuronal Dysfunction by Modulating the AKT/GSK-3β/CRMP-2 Pathway in Hippocampal Neurons
Zeng W, Zhang C, Long Q, Li Y
Neuropsychiatric Disease and Treatment 2021, 17:671-680
Published Date: 9 March 2021

Association of Serotonin Transporter (SERT) Polymorphisms with Opioid Dependence and Dimensional Aspects of Cocaine Use in a Caucasian Cohort of Opioid Users
Yuferov V, Butelman ER, Randesi M, van den Brink W, Blanken P, van Ree JM, Kreek MJ
Neuropsychiatric Disease and Treatment 2021, 17:659-670
Published Date: 25 February 2021

The Analysis of Anxiety and Depression in Different Stages of in vitro Fertilization-Embryo Transfer in Couples in China
Liu YF, Fu Z, Chen SW, He XP, Fan LY
Neuropsychiatric Disease and Treatment 2021, 17:649-657
Published Date: 25 February 2021

Treatment Efficacy and Clinical Effectiveness of EEG Neurofeedback as a Personalized and Multimodal Treatment in ADHD: A Critical Review
Garcia Pimenta M, Brown T, Arns M, Enriquez-Geppert S
Neuropsychiatric Disease and Treatment 2021, 17:637-648
Published Date: 25 February 2021
Peripheral Polyneuropathy and Cognitive Impairment in Type II Diabetes Mellitus
Elsharkawy RE, Abdel Azim GS, Osman MA, Maghraby HM, Mohamed RA, Abdelsalam EM, Ebrahem EE, Seliem NMA
Neuropsychiatric Disease and Treatment 2021, 17:627-635
Published Date: 24 February 2021

Berberine Suppresses Mice Depression Behaviors and Promotes Hippocampal Neurons Growth Through Regulating the miR-34b-5p/miR-470-5p/BDNF Axis
Zhan Y, Han J, Xia J, Wang X
Neuropsychiatric Disease and Treatment 2021, 17:613-626
Published Date: 22 February 2021

Changes in the Practice of Electroconvulsive Therapy in Poland: A Nationwide Survey Comparing Data Between 2005 and 2020
Antosik-Wójcińska AZ, Dominiak M, Mierzejewski P, Jażdżyk P, Gazdag G, Takacs R, Wichniak A
Neuropsychiatric Disease and Treatment 2021, 17:605-612
Published Date: 22 February 2021

Risk of Psychiatric Disorders in Multiple Sclerosis: A Nationwide Cohort Study in an Asian Population
Huang YC, Chien WC, Chung CH, Chang HA, Kao YC, Wan FJ, Huang SH, Chung RJ, Wang RS, Wang BL, Tzeng NS, Sun CA
Neuropsychiatric Disease and Treatment 2021, 17:587-604
Published Date: 22 February 2021

Efficacy of Vortioxetine on Anhedonia: Results from a Pooled Analysis of Short-Term Studies in Patients with Major Depressive Disorder
McIntyre RS, Loft H, Christensen MC
Neuropsychiatric Disease and Treatment 2021, 17:575-585
Published Date: 22 February 2021

Association Analysis Between Catechol-O-Methyltransferase Expression and Cognitive Function in Patients with Schizophrenia, Bipolar Disorder, or Major Depression
Ni P, Liu M, Wang D, Tian Y, Zhao L, Wei J, Yu X, Qi X, Li X, Yu H, Ni R, Ma X, Deng W, Guo W, Wang Q, Li T
Neuropsychiatric Disease and Treatment 2021, 17:567-574
Published Date: 22 February 2021

Comparative Study of the Effects of Atypical Antipsychotic Drugs on Plasma and Urine Biomarkers of Oxidative Stress in Schizophrenic Patients
Dietrich-Muszalska A, Kolodziejczyk-Czepas J, Nowak P
Neuropsychiatric Disease and Treatment 2021, 17:555-565
Published Date: 17 February 2021

Exploring the Impact of Modifiable Factors on Serum BDNF in Psychiatric Patients and Community Controls
Chan G, Rosic T, Pasyk S, Dehghan M, Samaan Z
Neuropsychiatric Disease and Treatment 2021, 17:545-554
Published Date: 17 February 2021

Therapeutic Effect of Idebenone on Rats with Vascular Dementia via the MicroRNA-216a/RSK2/NF-κB Axis
Qian X, Xu Q, Li G, Bu Y, Sun F, Zhang J
Neuropsychiatric Disease and Treatment 2021, 17:533-543
Published Date: 17 February 2021

Real-World Patterns of Utilization and Costs Associated with Second-Generation Oral Antipsychotic Medication for the Treatment of Bipolar Disorder: A Literature Review
Doane MJ, Ogden K, Bessonova L, O'Sullivan AK, Tohen M
Neuropsychiatric Disease and Treatment 2021, 17:515-531
Published Date: 16 February 2021
Serum miR-128 Serves as a Potential Diagnostic Biomarker for Alzheimer’s Disease [Corrigendum]
Zhang M, Han W, Xu Y, Li D, Xue Q
Neuropsychiatric Disease and Treatment 2021, 17:513-514
Published Date: 16 February 2021
The Relationship Between Antipsychotic Treatment and Plasma β-Endorphin Concentration in Patients with Schizophrenia
Urban-Kowalczyk M, Kotlicka-Antczak M, Strzelecki D, Rudecka E, Śmigielski J
Neuropsychiatric Disease and Treatment 2021, 17:503-512
Published Date: 16 February 2021

Asymmetry in Cortical and Subcortical Structures of the Brain in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
Chen S, Guan L, Tang J, He F, Zheng Y
Neuropsychiatric Disease and Treatment 2021, 17:493-502
Published Date: 12 February 2021

Hummingbird Study: Results from an Exploratory Trial Assessing the Performance and Acceptance of a Digital Medicine System in Adults with Schizophrenia, Schizoaffective Disorder, or First-Episode Psychosis
Fowler JC, Cope N, Knights J, Fang H, Skubiak T, Shergill SS, Phiri P, Rathod S, Peters-Strickland T
Neuropsychiatric Disease and Treatment 2021, 17:483-492
Published Date: 12 February 2021
MicroRNA-579-3p Exerts Neuroprotective Effects Against Ischemic Stroke via Anti-Inflammation and Anti-Apoptosis [Retraction]
Jia J, Cui Y, Tan Z, Ma W, Jiang Y
Neuropsychiatric Disease and Treatment 2021, 17:481-482
Published Date: 12 February 2021

Valproate Reverses Mania-Like Behavior of Clockdelta19 Mouse and Alters Monoamine Neurotransmitters Metabolism in the Hippocampus
Liu S, Wei J, Ni R, Gao T, Ni P, Zhao L, Duan X, Ma X, Sham PC, Li T
Neuropsychiatric Disease and Treatment 2021, 17:471-480
Published Date: 11 February 2021

A Review of Switching Strategies for Patients with Schizophrenia Comorbid with Metabolic Syndrome or Metabolic Abnormalities
Liao X, Ye H, Si T
Neuropsychiatric Disease and Treatment 2021, 17:453-469
Published Date: 11 February 2021

A Bidirectional View of Migraine and Diet Relationship
Gazerani P
Neuropsychiatric Disease and Treatment 2021, 17:435-451
Published Date: 11 February 2021

TGF-β1-Mediated Activation of SERPINE1 is Involved in Hemin-Induced Apoptotic and Inflammatory Injury in HT22 Cells
Wang T, Lu H, Li D, Huang W
Neuropsychiatric Disease and Treatment 2021, 17:423-433
Published Date: 11 February 2021

The Psychological Experience and Intervention in Post-Acute COVID-19 Inpatients
Rossi Ferrario S, Panzeri A, Cerutti P, Sacco D
Neuropsychiatric Disease and Treatment 2021, 17:413-422
Published Date: 11 February 2021

Serum Albumin Levels and Clinical Outcomes Among Ischemic Stroke Patients Treated with Endovascular Thrombectomy
Gao J, Zhao Y, Du M, Guo H, Wan T, Wu M, Liu L, Wang H, Yin Q, Liu X
Neuropsychiatric Disease and Treatment 2021, 17:401-411
Published Date: 10 February 2021
Hippocampal miRNA-144 Modulates Depressive-Like Behaviors in Rats by Targeting PTP1B
Li Y, Wang N, Pan J, Wang X, Zhao Y, Guo Z
Neuropsychiatric Disease and Treatment 2021, 17:389-399
Published Date: 10 February 2021

Prevalence of ADHD and Autism Spectrum Disorder in Children with Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome: A Retrospective Study
Kindgren E, Quiñones Perez A, Knez R
Neuropsychiatric Disease and Treatment 2021, 17:379-388
Published Date: 10 February 2021

Community Attitude Towards Epilepsy Patients and Associated Factors in South Achefer District, Northwest Ethiopia: A Mixed-Methods Study
Tirukelem H, Nigatu SG, Angaw DA, Azale T
Neuropsychiatric Disease and Treatment 2021, 17:365-377
Published Date: 9 February 2021
Usage of Angiotensin-Converting Enzyme Inhibitor or Angiotensin II Receptor Blocker in Hypertension Intracerebral Hemorrhage
Zhang C, Zhong J, Chen WX, Zhang XY, Li YH, Zhou TY, Zou YJ, Lan C, Li L, Lai ZP, Feng H, Hu R
Neuropsychiatric Disease and Treatment 2021, 17:355-363
Published Date: 9 February 2021

Association Between the SLC1A1 Glutamate Transporter Gene and Obsessive-Compulsive Disorder in the Chinese Han Population
Huang X, Liu J, Cong J, Zhang X
Neuropsychiatric Disease and Treatment 2021, 17:347-354
Published Date: 5 February 2021

Bushen Huoxue Acupuncture Inhibits NLRP1 Inflammasome-Mediated Neuronal Pyroptosis in SAMP8 Mouse Model of Alzheimer’s Disease
Zhang T, Guan B, Tan S, Zhu H, Ren D, Li R, Xiao L
Neuropsychiatric Disease and Treatment 2021, 17:339-346
Published Date: 5 February 2021

Identifying Early Neuropsychological Indicators of Cognitive Involvement in Multiple Sclerosis
Gromisch ES, Dhari Z
Neuropsychiatric Disease and Treatment 2021, 17:323-337
Published Date: 5 February 2021

Psychosomatic Stress Responses and Sleep Disturbance Mediate the Effects of Irregular Mealtimes on Presenteeism
Hayashida T, Shimura A, Higashiyama M, Fujimura Y, Ono K, Inoue T
Neuropsychiatric Disease and Treatment 2021, 17:315-321
Published Date: 4 February 2021

Gait and Balance Disorder in Patients with Transient Ischemic Attack or Minor Stroke
Li N, Li J, Gao T, Wang D, Du Y, Zhao X
Neuropsychiatric Disease and Treatment 2021, 17:305-314
Published Date: 3 February 2021
(2R,6R)-Hydroxynorketamine Alleviates Electroconvulsive Shock-Induced Learning Impairment by Inhibiting Autophagy
Zhong X, Ouyang C, Liang W, Dai C, Zhang W
Neuropsychiatric Disease and Treatment 2021, 17:297-304
Published Date: 3 February 2021


Cariprazine in Three Acute Patients with Schizophrenia: A Real-World Experience
Montes JM, Montes P, Hernández-Huerta D
Neuropsychiatric Disease and Treatment 2021, 17:291-296
Published Date: 3 February 2021

Prevalence and Predictors of Postictal Confusion After Electroconvulsive Therapy
Ittasakul P, Jarernrat P, Tor PC
Neuropsychiatric Disease and Treatment 2021, 17:283-289
Published Date: 2 February 2021

Irreversible Primary Visual Cortex Impairment in a Mouse Model of High-Risk Schizophrenia
Chen X, Chen C, Ji F, Xu Y, Wang W, Lin X, Jiang D, Song X, Gao X, Tian H, Zhuo C, Zhang J
Neuropsychiatric Disease and Treatment 2021, 17:277-282
Published Date: 29 January 2021
Serum miR-128 Serves as a Potential Diagnostic Biomarker for Alzheimer’s Disease
Zhang M, Han W, Xu Y, Li D, Xue Q
Neuropsychiatric Disease and Treatment 2021, 17:269-275
Published Date: 29 January 2021

Schisandrin Inhibits NLRP1 Inflammasome-Mediated Neuronal Pyroptosis in Mouse Models of Alzheimer’s Disease
Li Q, Wang Q, Guan H, Zhou Y, Liu L
Neuropsychiatric Disease and Treatment 2021, 17:261-268
Published Date: 29 January 2021

Investigation of Changes in Retinal Detachment-Related Brain Region Activities and Functions Using the Percent Amplitude of Fluctuation Method: A Resting-State Functional Magnetic Resonance Imaging Study
Yang YC, Li QY, Chen MJ, Zhang LJ, Zhang MY, Pan YC, Ge QM, Shu HY, Lin Q, Shao Y
Neuropsychiatric Disease and Treatment 2021, 17:251-260
Published Date: 28 January 2021

Effects of Antipsychotics on Arrhythmogenic Parameters in Schizophrenia Patients: Beyond Corrected QT Interval
Okayasu H, Shinozaki T, Takano Y, Sugawara N, Fujii K, Yasui-Furukori N, Ozeki Y, Shimoda K
Neuropsychiatric Disease and Treatment 2021, 17:239-249
Published Date: 27 January 2021

Reliability and Validity of the Chen ADHD Scale (C-ADHDS)
Chen YL, Chen VCH, Gossop M
Neuropsychiatric Disease and Treatment 2021, 17:229-237
Published Date: 27 January 2021
Factor Structure and Measurement Invariance of the Hospital Anxiety and Depression Scale Across the Peripartum Period Among Pregnant Japanese Women
Ogawa M, Watanabe Y, Motegi T, Fukui N, Hashijiri K, Tsuboya R, Sugai T, Egawa J, Araki R, Haino K, Yamaguchi M, Nishijima K, Enomoto T, Someya T
Neuropsychiatric Disease and Treatment 2021, 17:221-227
Published Date: 26 January 2021

Association Between Stressful Life Events and Female Primary Sjogren’s Syndrome and Their Role in Disease Activity: A Retrospective Case–Control Study in China
Meng FY, Ren S, Meng Y, Tao N, Zhang J
Neuropsychiatric Disease and Treatment 2021, 17:213-220
Published Date: 25 January 2021

Clinical Features and Long-Term Outcomes of Anti-Leucine-Rich Glioma-Inactivated 1 Encephalitis: A Multi-Center Study
Qiao S, Wu H, Liu L, Wang M, Zhang R, Han T, Liu X
Neuropsychiatric Disease and Treatment 2021, 17:203-212
Published Date: 25 January 2021
Addition of Aβ42 to Total Cerebral Small Vessel Disease Score Improves the Prediction for Cognitive Impairment in Cerebral Small Vessel Disease Patients
Liu J, Zhao W, Gui Q, Zhang Y, Guo Z, Liu W
Neuropsychiatric Disease and Treatment 2021, 17:195-201
Published Date: 25 January 2021

Exploring the Effects of Temperament on Gray Matter Volume of Frontal Cortex in Patients with Mood Disorders
Yang T, Lam RW, Huang J, Su Y, Liu J, Yang X, Yang L, Zhu N, Zhao G, Mao R, Zhou R, Xia W, Liu H, Wang Z, Chen J, Fang Y
Neuropsychiatric Disease and Treatment 2021, 17:183-193
Published Date: 22 January 2021
Diffusion Tensor Tractography Characteristics of White Matter Tracts are Associated with Post-Stroke Depression
Deng L, Sui R, Zhang L
Neuropsychiatric Disease and Treatment 2021, 17:167-181
Published Date: 25 January 2021

Synaptic Microenvironment in Depressive Disorder: Insights from Synaptic Plasticity
Ren F, Guo R
Neuropsychiatric Disease and Treatment 2021, 17:157-165
Published Date: 22 January 2021
Circular RNA circPHC3 Promotes Cell Death and Apoptosis in Human BMECs After Oxygen Glucose Deprivation via miR-455-5p/TRAF3 Axis in vitro
Xu X, Wu Z, Qiu H, Wu J
Neuropsychiatric Disease and Treatment 2021, 17:147-156
Published Date: 22 January 2021

Anxiety and Stress Among Undergraduate Medical Students of Haramaya University, Eastern Ethiopia
Asfaw H, Fekadu G, Tariku M, Oljira A
Neuropsychiatric Disease and Treatment 2021, 17:139-146
Published Date: 22 January 2021


Schizophrenia Treatment with Second-Generation Antipsychotics: A Multi-Country Comparison of the Costs of Cardiovascular and Metabolic Adverse Events and Weight Gain
Kearns B, Cooper K, Cantrell A, Thomas C
Neuropsychiatric Disease and Treatment 2021, 17:125-137
Published Date: 20 January 2021

The Health-Related Quality of Life, Work Productivity, Healthcare Resource Utilization, and Economic Burden Associated with Levels of Suicidal Ideation Among Patients Self-Reporting Moderately Severe or Severe Major Depressive Disorder in a National Survey
Benson C, Singer D, Carpinella CM, Shawi M, Alphs L
Neuropsychiatric Disease and Treatment 2021, 17:111-123
Published Date: 18 January 2021

A Retrospective Study of Patients with GABABR Encephalitis: Therapy, Disease Activity and Prognostic Factors
Wen X, Wang B, Wang C, Han C, Guo S
Neuropsychiatric Disease and Treatment 2021, 17:99-110
Published Date: 18 January 2021


Behavior Disorder and Social Function Impairment in Children with Basal Ganglia Germ Cell Tumors
Lv W, Feng J, Chen L, Liu S, Qiu X
Neuropsychiatric Disease and Treatment 2021, 17:91-98
Published Date: 14 January 2021

Implementing Measurement-Based Care for Depression: Practical Solutions for Psychiatrists and Primary Care Physicians
Hong RH, Murphy JK, Michalak EE, Chakrabarty T, Wang Z, Parikh SV, Culpepper L, Yatham LN, Lam RW, Chen J
Neuropsychiatric Disease and Treatment 2021, 17:79-90
Published Date: 14 January 2021
Clinical Manifestations, Fluid Changes and Neuroimaging Alterations in Patients with General Paresis of the Insane
Gao JH, Li WR, Xu DM, Zheng BW, Huang YM, Wu WQ, Zhang W
Neuropsychiatric Disease and Treatment 2021, 17:69-78
Published Date: 13 January 2021
Impact of Supporting People with Advanced Parkinson’s Disease on Carer’s Quality of Life and Burden [Corrigendum]
Modugno N, Antonini A, Tessitore A, Marano P, Pontieri FE, Tambasco N, Canesi M, Fabbrini G, Sensi M, Quatrale R, Solla P, Defazio G, Melzi G, Gualberti G, Lopiano L
Neuropsychiatric Disease and Treatment 2021, 17:67-68
Published Date: 13 January 2021
Association of Depression with Metabolic Syndrome in Highly Educated Ethnic Koreans of China: A Case–Control Study
Wen Y, Liu G, Shang Y, Wang Q
Neuropsychiatric Disease and Treatment 2021, 17:57-66
Published Date: 8 January 2021
MicroRNA-488-3p Regulates Neuronal Cell Death in Cerebral Ischemic Stroke Through Vacuolar Protein Sorting 4B (VPS4B)
Zhou L, Yang W, Yao E, Li H, Wang J, Wang K, Zhong X, Peng Z, Huang X
Neuropsychiatric Disease and Treatment 2021, 17:41-55
Published Date: 7 January 2021
Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
Zhang Y, Ye Z, Fu Y, Zhang Z, Ye Q, Chen F, Cheng J
Neuropsychiatric Disease and Treatment 2021, 17:33-40
Published Date: 7 January 2021

The Impact of Methylphenidate on QbTest Performance of Children with ADHD: A Retrospective Clinical Study
Knez R, Stevanovic D, Nasic S, Doric A, Wentz E
Neuropsychiatric Disease and Treatment 2021, 17:19-32
Published Date: 6 January 2021
Association of Serum Dystroglycan, MMP-2/9 and AQP-4 with Haematoma Expansion in Patients with Intracerebral Haemorrhage
Shi Y, Fan X, Li G, Zhong D, Zhang X
Neuropsychiatric Disease and Treatment 2021, 17:11-18
Published Date: 6 January 2021

Defining “Adequately Treated”: A Post Hoc Analysis Examining Characteristics of Patients with Schizophrenia Successfully Transitioned from Once-Monthly Paliperidone Palmitate to Once-Every-3-Months Paliperidone Palmitate
O'Donnell A, Rao S, Turkoz I, Gopal S, Kim E
Neuropsychiatric Disease and Treatment 2021, 17:1-9
Published Date: 6 January 2021