Kaseb AO, Kappadath SC, Lee SS, Raghav KP, Mohamed YI, Xiao L, Morris JS, Ohaji C, Avritscher R, Odisio BC, Kuban J, Abdelsalam ME, Chasen B, Elsayes KM, Elbanan M, Wolff RA, Yao JC, Mahvash A

Journal of Hepatocellular Carcinoma 2021, 8:1129-1145

Published Date: 9 September 2021

Case Series

Primary Liver Sarcomatoid Carcinoma: A Case Series and Literature Review

Ji W, Xing Y, Ma J, Zhao Z, Xu H, Zheng S, Li W, Li X

Journal of Hepatocellular Carcinoma 2021, 8:1117-1127

Published Date: 7 September 2021

Review

Portal Vein Tumor Thrombosis and Hepatocellular Carcinoma – The Changing Tides

Khan AR, Wei X, Xu X

Journal of Hepatocellular Carcinoma 2021, 8:1089-1115

Published Date: 7 September 2021

Review

An Overview of the Genomic Characterization of Hepatocellular Carcinoma

Yim SY, Lee JS

Journal of Hepatocellular Carcinoma 2021, 8:1077-1088

Published Date: 7 September 2021

Original Research

Deep Learning-Based Prediction of Future Extrahepatic Metastasis and Macrovascular Invasion in Hepatocellular Carcinoma

Fu S, Pan M, Zhang J, Zhang H, Tang Z, Li Y, Mu W, Huang J, Dong D, Duan C, Li X, Wang S, Chen X, He X, Yan J, Lu L, Tian J

Journal of Hepatocellular Carcinoma 2021, 8:1065-1076

Published Date: 4 September 2021

Original Research

A Genetic Variant of PPP1CB Influences Risk of Hepatitis B Virus-Related Hepatocellular Carcinoma in Han Chinese: A Pathway Based Analysis

Mai H, Xie H, Hou J, Chen H, Zhou B, Hou J, Jiang D

Journal of Hepatocellular Carcinoma 2021, 8:1055-1064

Published Date: 2 September 2021

Review

Peptide-Based Vaccines for Hepatocellular Carcinoma: A Review of Recent Advances

Charneau J, Suzuki T, Shimomura M, Fujinami N, Nakatsura T

Journal of Hepatocellular Carcinoma 2021, 8:1035-1054

Published Date: 2 September 2021

Original Research

Liver Cancer Survival: A Real World Observation of 45 Years with 32,556 Cases

Chen JG, Zhu J, Zhang YH, Chen YS, Ding LL, Chen HZ, Shen AG, Wang GR

Journal of Hepatocellular Carcinoma 2021, 8:1023-1034

Published Date: 31 August 2021

Original Research

Regulation Network and Prognostic Significance of Aldo-Keto Reductase (AKR) Superfamily Genes in Hepatocellular Carcinoma

Dai T, Ye L, Yu H, Li K, Li J, Liu R, Lu X, Deng M, Li R, Liu W, Yang Y, Wang G

Journal of Hepatocellular Carcinoma 2021, 8:997-1021

Published Date: 30 August 2021

Review

Molecular Targets of Ferroptosis in Hepatocellular Carcinoma

Liao H, Shi J, Wen K, Lin J, Liu Q, Shi B, Yan Y, Xiao Z

Journal of Hepatocellular Carcinoma 2021, 8:985-996

Published Date: 24 August 2021

Original Research

MR Features Based on LI-RADS Ver. 2018 Correlated with Cytokeratin 19 Expression in Combined Hepatocellular Carcinoma-Cholangiocarcinoma

Zhou C, Ni X, Lu X, Wang Y, Qian X, Yang C, Zeng M

Journal of Hepatocellular Carcinoma 2021, 8:975-983

Published Date: 21 August 2021

Original Research

Concurrent Sorafenib and Radiotherapy versus Radiotherapy Alone for Locally Advanced Hepatocellular Carcinoma: A Propensity-Matched Analysis

Liu CM, Huang BS, Yen YH, Wang YM, Huang EY, Hsu HC, Huang TT, Yang YH, Cheng JY

Journal of Hepatocellular Carcinoma 2021, 8:963-973

Published Date: 18 August 2021

Original Research

Fine Mapping of the MHC Region Identifies Novel Variants Associated with HBV-Related Hepatocellular Carcinoma in Han Chinese

Mai H, Chen J, Chen H, Liu Z, Huang G, Wang J, Xiao Q, Ren W, Zhou B, Hou J, Jiang D

Journal of Hepatocellular Carcinoma 2021, 8:951-961

Published Date: 16 August 2021

Review

Transcatheter Arterial Chemoembolization with Drug-Eluting Beads for the Treatment of Hepatocellular Carcinoma: Recommended Selection for Small-Caliber (<100 μm) Beads

Chang WC, Hsu HH, Chiu SH, Huang WY, Lo CH, Lin HH, Huang PC, Shih YL, Wan YL

Journal of Hepatocellular Carcinoma 2021, 8:937-949

Published Date: 14 August 2021

Original Research

Decreased Incidence of Hepatocellular Carcinoma after Directly Acting Antiviral Therapy in Patients with Hepatitis C–Related Advanced Fibrosis and Cirrhosis

Kilany S, Ata L, Gomaa A, Sabry A, Nada A, Tharwa ES, Badra G, Abogabal A, Elwaraky M, Moaz E, Ezzat S, Elsharawy A, Waked I

Journal of Hepatocellular Carcinoma 2021, 8:925-935

Published Date: 12 August 2021

Original Research

Machine Learning to Improve Prognosis Prediction of Early Hepatocellular Carcinoma After Surgical Resection

Ji GW, Fan Y, Sun DW, Wu MY, Wang K, Li XC, Wang XH

Journal of Hepatocellular Carcinoma 2021, 8:913-923

Published Date: 10 August 2021

Original Research

SLC39A10 Upregulation Predicts Poor Prognosis, Promotes Proliferation and Migration, and Correlates with Immune Infiltration in Hepatocellular Carcinoma

Ma Z, Li Z, Wang S, Zhou Q, Ma Z, Liu C, Huang B, Zheng Z, Yang L, Zou Y, Zhang C, Huang S, Hou B

Journal of Hepatocellular Carcinoma 2021, 8:899-912

Published Date: 7 August 2021

Review

PD-1 Blockade for Hepatocellular Carcinoma: Current Research and Future Prospects

D'Alessio A, Rimassa L, Cortellini A, Pinato DJ

Journal of Hepatocellular Carcinoma 2021, 8:887-897

Published Date: 5 August 2021

Original Research

DTYMK Expression Predicts Prognosis and Chemotherapeutic Response and Correlates with Immune Infiltration in Hepatocellular Carcinoma

Guo Y, Luo W, Huang S, Zhao W, Chen H, Ma Y, Ye M, Nie Y, Zhang Y, Huang C, Zhou Q, He X, Chen M

Journal of Hepatocellular Carcinoma 2021, 8:871-885

Published Date: 3 August 2021

Original Research

Biochemical Safety of Ablative Yttrium-90 Radioembolization for Hepatocellular Carcinoma as a Function of Percent Liver Treated

De la Garza-Ramos C, Overfield CJ, Montazeri SA, Liou H, Paz-Fumagalli R, Frey GT, McKinney JM, Ritchie CA, Devcic Z, Lewis AR, Harnois DM, Patel T, Toskich BB

Journal of Hepatocellular Carcinoma 2021, 8:861-870

Published Date: 30 July 2021

Review

Challenging the Treatment Paradigm: Selecting Patients for Surgical Management of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Nevarez NM, Yopp AC

Journal of Hepatocellular Carcinoma 2021, 8:851-860

Published Date: 28 July 2021

Original Research

Using the aMAP Risk Score to Predict Late Recurrence Following Radiofrequency Ablation for Hepatocellular Carcinoma in Chinese Population: A Multicenter Study

Yang Y, Zhou Y, Zhang X, Xin Y, Chen Y, Fan Q, Li X, Wei X, Li Q, Zhou X, Zhou J

Journal of Hepatocellular Carcinoma 2021, 8:837-850

Published Date: 28 July 2021

Original Research

DNA and RNA Sequencing Recapitulated Aberrant Tumor Metabolism in Liver Cancer Cell Lines

Sun Y, Tang X, Ye B, Ding K

Journal of Hepatocellular Carcinoma 2021, 8:823-836

Published Date: 27 July 2021

Original Research

An Exploratory Study for the Association of Gut Microbiome with Efficacy of Immune Checkpoint Inhibitor in Patients with Hepatocellular Carcinoma

Shen YC, Lee PC, Kuo YL, Wu WK, Chen CC, Lei CH, Yeh CP, Hsu C, Hsu CH, Lin ZZ, Shao YY, Lu LC, Liu TH, Chen CH, Wu MS, Huang YH, Cheng AL

Journal of Hepatocellular Carcinoma 2021, 8:809-822

Published Date: 24 July 2021

Original Research

Preoperative Prediction of Cytokeratin 19 Expression for Hepatocellular Carcinoma with Deep Learning Radiomics Based on Gadoxetic Acid-Enhanced Magnetic Resonance Imaging

Chen Y, Chen J, Zhang Y, Lin Z, Wang M, Huang L, Huang M, Tang M, Zhou X, Peng Z, Huang B, Feng ST

Journal of Hepatocellular Carcinoma 2021, 8:795-808

Published Date: 22 July 2021

Original Research

Construction and Validation of a Nomogram for Predicting the Risk of Deep Vein Thrombosis in Hepatocellular Carcinoma Patients After Laparoscopic Hepatectomy: A Retrospective Study

Chen Y, Zhao J, Zhang Z, Ding Z, Chen Y, Chen X, Zhang W

Journal of Hepatocellular Carcinoma 2021, 8:783-794

Published Date: 21 July 2021

Original Research

Prediction of Hepatocellular Carcinoma Response to Transcatheter Arterial Chemoembolization: A Real-World Study Based on Non-Contrast Computed Tomography Radiomics and General Image Features

Guo Z, Zhong N, Xu X, Zhang Y, Luo X, Zhu H, Zhang X, Wu D, Qiu Y, Tu F

Journal of Hepatocellular Carcinoma 2021, 8:773-782

Published Date: 9 July 2021

Original Research

SERPINA11 Inhibits Metastasis in Hepatocellular Carcinoma by Suppressing MEK/ERK Signaling Pathway

Song Y, Li Z, Li L, Zhou H, Zeng TT, Jin C, Lin JR, Gao S, Li Y, Guan XY, Zhu YH

Journal of Hepatocellular Carcinoma 2021, 8:759-771

Published Date: 6 July 2021

Review

Elucidating the Molecular Basis of Sorafenib Resistance in HCC: Current Findings and Future Directions

Fornari F, Giovannini C, Piscaglia F, Gramantieri L

Journal of Hepatocellular Carcinoma 2021, 8:741-757

Published Date: 2 July 2021

Review

Predicting Hepatocellular Carcinoma Risk in Patients with Chronic HCV Infection and a Sustained Virological Response to Direct-Acting Antivirals

D'Ambrosio R, Degasperi E, Lampertico P

Journal of Hepatocellular Carcinoma 2021, 8:713-739

Published Date: 29 June 2021

Original Research

Outcomes in the Era of Interferon-Free Direct-Acting Antiviral Therapy After Liver Transplantation in Patients with Hepatitis C Virus and Hepatocellular Carcinoma

Ismail MS, Mohamed I, Polychronopoulou E, Goss JA, Kuo YF, Kanwal F, Jalal PK

Journal of Hepatocellular Carcinoma 2021, 8:701-711

Published Date: 29 June 2021

Original Research

Inhibition of SIRT1 Limits Self-Renewal and Oncogenesis by Inducing Senescence of Liver Cancer Stem Cells

Wang MJ, Chen JJ, Song SH, Su J, Zhao LH, Liu QG, Yang T, Chen Z, Liu C, Fu ZR, Hu YP, Chen F

Journal of Hepatocellular Carcinoma 2021, 8:685-699

Published Date: 29 June 2021

Original Research

A Semi-Automatic Step-by-Step Expert-Guided LI-RADS Grading System Based on Gadoxetic Acid-Enhanced MRI

Sheng R, Huang J, Zhang W, Jin K, Yang L, Chong H, Fan J, Zhou J, Wu D, Zeng M

Journal of Hepatocellular Carcinoma 2021, 8:671-683

Published Date: 29 June 2021

Original Research

Prognostic Values of Alpha-Fetoprotein and Des-Gamma-Carboxyprothrombin in Hepatocellular Carcinoma in China: An Analysis of 4792 Patients

Pan YX, Sun XQ, Hu ZL, Xie W, Nie KX, Fang AP, Zhang YY, Fu YZ, Chen JB, Wang JC, Wang X, Zhang YJ, Hu DD, Chen MS

Journal of Hepatocellular Carcinoma 2021, 8:657-670

Published Date: 25 June 2021

Original Research

An Optimized Integrin α6-Targeted Magnetic Resonance Probe for Molecular Imaging of Hepatocellular Carcinoma in Mice

Lin BQ, Zhang WB, Zhao J, Zhou XH, Li YJ, Deng J, Zhao Q, Fu G, Xie CM, Xu YK, Feng GK

Journal of Hepatocellular Carcinoma 2021, 8:645-656

Published Date: 24 June 2021

Review

Challenges Facing Percutaneous Ablation in the Treatment of Hepatocellular Carcinoma: Extension of Ablation Criteria

Zhou Y, Yang Y, Zhou B, Wang Z, Zhu R, Chen X, Ouyang J, Li Q, Zhou J

Journal of Hepatocellular Carcinoma 2021, 8:625-644

Published Date: 21 June 2021

Original Research

Clinical Characteristics of Long-Term Survivors After Sorafenib Treatment for Unresectable Hepatocellular Carcinoma: A Korean National Multicenter Retrospective Cohort Study

Cho YY, Yu SJ, Lee HW, Kim DY, Kang W, Paik YH, Sung PS, Bae SH, Park SC, Doh YS, Kim KM, Jang ES, Kim IH, Kim W, Kim YJ

Journal of Hepatocellular Carcinoma 2021, 8:613-623

Published Date: 18 June 2021

Original Research

Blocking the CCL5–CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells

Zhuang Y, Zhao X, Yuan B, Zeng ZC, Chen Y

Journal of Hepatocellular Carcinoma 2021, 8:599-611

Published Date: 18 June 2021

Original Research

Effectiveness of Transarterial Chemoembolization-First Treatment for Advanced Hepatocellular Carcinoma: A Propensity Score Matching Analysis

Chung SW, Park MK, Cho YY, Park Y, Lee CH, Oh H, Jang H, Kim MA, Kim SW, Nam JY, Lee YB, Cho EJ, Yu SJ, Kim HC, Kim YJ, Chung JW, Yoon JH, Lee JH

Journal of Hepatocellular Carcinoma 2021, 8:587-598

Published Date: 15 June 2021

Review

Current Understanding of Ablative Radiation Therapy in Hepatocellular Carcinoma

Mathew AS, Dawson LA

Journal of Hepatocellular Carcinoma 2021, 8:575-586

Published Date: 14 June 2021

Original Research

Rates of Hepatocellular Carcinoma After Start of Treatment for Chronic Hepatitis C Remain High with Direct Acting Antivirals: Analysis from a Swiss Liver Transplant Center

Karbeyaz F, Kissling S, Jaklin PJ, Bachofner J, Brunner B, Müllhaupt B, Winder T, Mertens JC, Misselwitz B, von Felten S, Siebenhüner AR

Journal of Hepatocellular Carcinoma 2021, 8:565-574

Published Date: 11 June 2021

Original Research

Peritumoral Dilation Radiomics of Gadoxetate Disodium-Enhanced MRI Excellently Predicts Early Recurrence of Hepatocellular Carcinoma without Macrovascular Invasion After Hepatectomy

Chong H, Gong Y, Pan X, Liu A, Chen L, Yang C, Zeng M

Journal of Hepatocellular Carcinoma 2021, 8:545-563

Published Date: 9 June 2021

Original Research

The Combination Immunotherapy of TLR9 Agonist and OX40 Agonist via Intratumoural Injection for Hepatocellular Carcinoma

Zhou Z, Lin L, An Y, Zhan M, Chen Y, Cai M, Zhu X, Lu L, Zhu K

Journal of Hepatocellular Carcinoma 2021, 8:529-543

Published Date: 8 June 2021

Review

Up-to-Date Role of CT/MRI LI-RADS in Hepatocellular Carcinoma

Moura Cunha G, Chernyak V, Fowler KJ, Sirlin CB

Journal of Hepatocellular Carcinoma 2021, 8:513-527

Published Date: 31 May 2021

Original Research

Clinical Indicators for Long-Term Survival with Immune Checkpoint Therapy in Advanced Hepatocellular Carcinoma

Monge C, Xie C, Steinberg SM, Greten TF

Journal of Hepatocellular Carcinoma 2021, 8:507-512

Published Date: 31 May 2021

Original Research

Prognostic Model for the Risk Stratification of Early and Late Recurrence in Hepatitis B Virus-Related Small Hepatocellular Carcinoma Patients with Global Histone Modifications

Duan JL, Nie RC, Xiang ZC, Chen JW, Deng MH, Liang H, Wang FW, Luo RZ, Xie D, Cai MY

Journal of Hepatocellular Carcinoma 2021, 8:493-505

Published Date: 28 May 2021

Review

Regorafenib Combined with Other Systemic Therapies: Exploring Promising Therapeutic Combinations in HCC

Granito A, Marinelli S, Forgione A, Renzulli M, Benevento F, Piscaglia F, Tovoli F

Journal of Hepatocellular Carcinoma 2021, 8:477-492

Published Date: 26 May 2021

Original Research

The Prognostic Role of On-Treatment Liver Stiffness for Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B

Lee HW, Lee HW, Lee JS, Roh YH, Lee H, Kim SU, Park JY, Kim DY, Ahn SH, Kim BK

Journal of Hepatocellular Carcinoma 2021, 8:467-476

Published Date: 25 May 2021

Original Research

The Crosstalk Between Cancer Cells and Neutrophils Enhances Hepatocellular Carcinoma Metastasis via Neutrophil Extracellular Traps-Associated Cathepsin G Component: A Potential Therapeutic Target

Guan X, Lu Y, Zhu H, Yu S, Zhao W, Chi X, Xie C, Yin Z

Journal of Hepatocellular Carcinoma 2021, 8:451-465

Published Date: 20 May 2021

Review

The Mechanisms of HBV-Induced Hepatocellular Carcinoma

Jiang Y, Han Q, Zhao H, Zhang J

Journal of Hepatocellular Carcinoma 2021, 8:435-450

Published Date: 20 May 2021

Clinical Trial Report

Phase I Trial on Arterial Embolization with Hypoxia Activated Tirapazamine for Unresectable Hepatocellular Carcinoma

Abi-Jaoudeh N, Dayyani F, Chen PJ, Fernando D, Fidelman N, Javan H, Liang PC, Hwang JI, Imagawa DK

Journal of Hepatocellular Carcinoma 2021, 8:421-434

Published Date: 17 May 2021

Review

Current Strategies to Identify Patients That Will Benefit from TACE Treatment and Future Directions a Practical Step-by-Step Guide

Müller L, Stoehr F, Mähringer-Kunz A, Hahn F, Weinmann A, Kloeckner R

Journal of Hepatocellular Carcinoma 2021, 8:403-419

Published Date: 13 May 2021

Review

Hepatocellular Carcinoma: An Overview of the Changing Landscape of Treatment Options

Koulouris A, Tsagkaris C, Spyrou V, Pappa E, Troullinou A, Nikolaou M

Journal of Hepatocellular Carcinoma 2021, 8:387-401

Published Date: 13 May 2021

Review

MicroRNAs as Modulators of Tumor Metabolism, Microenvironment, and Immune Response in Hepatocellular Carcinoma

Gramantieri L, Giovannini C, Piscaglia F, Fornari F

Journal of Hepatocellular Carcinoma 2021, 8:369-385

Published Date: 12 May 2021

Original Research

Clinical, Pathological and Genetic Characteristics of Pediatric Hepatocellular Carcinoma Associated with Hepatitis B Virus Infection

Zhao P, Lu Y, Wang C, Wang L, Li J, Li M

Journal of Hepatocellular Carcinoma 2021, 8:361-367

Published Date: 10 May 2021

Original Research

Texture Analysis Based on Gd-EOB-DTPA-Enhanced MRI for Identifying Vessels Encapsulating Tumor Clusters (VETC)-Positive Hepatocellular Carcinoma

Fan Y, Yu Y, Wang X, Hu M, Du M, Guo L, Sun S, Hu C

Journal of Hepatocellular Carcinoma 2021, 8:349-359

Published Date: 5 May 2021

Original Research

LncRNA-CCDC144NL-AS1 Promotes the Development of Hepatocellular Carcinoma by Inducing WDR5 Expression via Sponging miR-940

Zhang Y, Zhang H, Wu S

Journal of Hepatocellular Carcinoma 2021, 8:333-348

Published Date: 3 May 2021

Original Research

Current Status of Therapeutic Choice and Feasibility for Patients with Hepatocellular Carcinoma Aged ≥ 70 Years: A Nationwide Cancer Registry Analysis

Rho SY, Lee HW, Kim DY, Kim KS

Journal of Hepatocellular Carcinoma 2021, 8:321-332

Published Date: 30 April 2021

Original Research

Impact of Sarcopenia on Two-Year Mortality in Patients with HCV-Associated Hepatocellular Carcinoma After Radiofrequency Ablation

Salman A, Salman M, Moustafa A, Shaaban HE, El-Mikkawy A, Labib S, Youssef A, Omar MG, Matter M, Elkassar H

Journal of Hepatocellular Carcinoma 2021, 8:313-320

Published Date: 29 April 2021

Original Research

Development of Prognostic Evaluation Model to Predict the Overall Survival and Early Recurrence of Hepatocellular Carcinoma

Zhong Y, Yang Y, He L, Zhou Y, Cheng N, Chen G, Zhao B, Wang Y, Wang G, Liu X

Journal of Hepatocellular Carcinoma 2021, 8:301-312

Published Date: 29 April 2021

Original Research

Serum Levels of ITGBL1 as an Early Diagnostic Biomarker for Hepatocellular Carcinoma with Hepatitis B Virus Infection

Ye F, Huang W, Xue Y, Tang E, Wang M, Shi F, Wei D, Han Y, Chen P, Zhang X, Yu D

Journal of Hepatocellular Carcinoma 2021, 8:285-300

Published Date: 27 April 2021

Original Research

ARHGAP20 Expression Inhibited HCC Progression by Regulating the PI3K-AKT Signaling Pathway

Liu G, Li J, Zhang CY, Huang DY, Xu JW

Journal of Hepatocellular Carcinoma 2021, 8:271-284

Published Date: 21 April 2021

Original Research

Ultrasound-Guided Percutaneous Ethanol-Paclitaxel Combined Therapy for Rabbit VX2 Liver Tumors

Chen L, Liu ZX, Bi QC, Zhao J, Liang QR, Tang Q

Journal of Hepatocellular Carcinoma 2021, 8:263-270

Published Date: 20 April 2021

Original Research

Selecting an Optimal Staging System for Intermediate-Stage Hepatocellular Carcinoma: Comparison of 9 Currently Used Prognostic Models

Zhang YF, Shi M, Lu LH, Wang L, Guo RP

Journal of Hepatocellular Carcinoma 2021, 8:253-261

Published Date: 19 April 2021

Review

A Comparison of Lenvatinib versus Sorafenib in the First-Line Treatment of Unresectable Hepatocellular Carcinoma: Selection Criteria to Guide Physician’s Choice in a New Therapeutic Scenario

Dipasquale A, Marinello A, Santoro A

Journal of Hepatocellular Carcinoma 2021, 8:241-251

Published Date: 15 April 2021

Review

NAFLD-Associated HCC: Progress and Opportunities

Geh D, Anstee QM, Reeves HL

Journal of Hepatocellular Carcinoma 2021, 8:223-239

Published Date: 8 April 2021

Original Research

High Expression of PIGC Predicts Unfavorable Survival in Hepatocellular Carcinoma

Guo X, Tian S, Cao P, Xie Y, Dong W

Journal of Hepatocellular Carcinoma 2021, 8:211-222

Published Date: 6 April 2021

Original Research

Development and Validation of a Metabolic Gene-Based Prognostic Signature for Hepatocellular Carcinoma

Weng J, Zhou C, Zhou Q, Chen W, Yin Y, Atyah M, Dong Q, Shi Y, Ren N

Journal of Hepatocellular Carcinoma 2021, 8:193-209

Published Date: 29 March 2021

Review

The Role of Cabozantinib as a Therapeutic Option for Hepatocellular Carcinoma: Current Landscape and Future Challenges

D'Alessio A, Prete MG, Cammarota A, Personeni N, Rimassa L

Journal of Hepatocellular Carcinoma 2021, 8:177-191

Published Date: 29 March 2021

Original Research

Anti-PD-1 Immunotherapy Improves the Efficacy of Hepatic Artery Infusion Chemotherapy in Advanced Hepatocellular Carcinoma

Mei J, Li SH, Li QJ, Sun XQ, Lu LH, Lin WP, Zheng L, Chen MS, Shi M, Wei W, Guo RP

Journal of Hepatocellular Carcinoma 2021, 8:167-176

Published Date: 25 March 2021

Original Research

Short- and Long-Term Outcomes After Hepatectomy in Elderly Patients with Hepatocellular Carcinoma: An Analysis of 229 Cases from a Developing Country

Galun D, Bogdanovic A, Zivanovic M, Zuvela M

Journal of Hepatocellular Carcinoma 2021, 8:155-165

Published Date: 23 March 2021

Review

Comparison of Efficacy of Systemic Therapies in Advanced Hepatocellular Carcinoma: Updated Systematic Review and Frequentist Network Meta-Analysis of Randomized Controlled Trials

Park R, Lopes da Silva L, Nissaisorakarn V, Riano I, Williamson S, Sun W, Saeed A

Journal of Hepatocellular Carcinoma 2021, 8:145-154

Published Date: 22 March 2021

Original Research

Recurrence of Hepatocellular Carcinoma After Liver Transplantation is Associated with Episodes of Acute Rejections

Gül-Klein S, Kästner A, Haber PK, Krenzien F, Wabitsch S, Krannich A, Andreou A, Eurich D, Tacke F, Horst D, Pratschke J, Schmelzle M

Journal of Hepatocellular Carcinoma 2021, 8:133-143

Published Date: 18 March 2021

Original Research

A Novel Metabolism-Related Signature as a Candidate Prognostic Biomarker for Hepatocellular Carcinoma

Wang Z, Embaye KS, Yang Q, Qin L, Zhang C, Liu L, Zhan X, Zhang F, Wang X, Qin S

Journal of Hepatocellular Carcinoma 2021, 8:119-132

Published Date: 16 March 2021

Original Research

Association of Postoperative Biomarker Response with Recurrence and Survival in Patients with Hepatocellular Carcinoma and High Alpha-Fetoprotein Expressions (>400 ng/ml)

Liang L, Wang MD, Zhang YM, Zhang WG, Zhang CW, Lau WY, Shen F, Pawlik TM, Huang DS, Yang T

Journal of Hepatocellular Carcinoma 2021, 8:103-118

Published Date: 12 March 2021

Original Research

Gene Expression Profile and Prognostic Value of m6A RNA Methylation Regulators in Hepatocellular Carcinoma

Chang X, Lv YF, He J, Cao Y, Li CQ, Guo QN

Journal of Hepatocellular Carcinoma 2021, 8:85-101

Published Date: 12 March 2021

Original Research

Imaging, Pathology, and Immune Correlates in the Woodchuck Hepatic Tumor Model

Mauda-Havakuk M, Mikhail AS, Starost MF, Jones EC, Karim B, Kleiner DE, Partanen A, Esparza-Trujillo JA, Bakhutashvili I, Wakim PG, Kassin MT, Lewis AL, Karanian JW, Wood BJ, Pritchard WF

Journal of Hepatocellular Carcinoma 2021, 8:71-83

Published Date: 9 March 2021

Original Research

Radiation-Associated Lymphopenia and Outcomes of Patients with Unresectable Hepatocellular Carcinoma Treated with Radiotherapy

De B, Ng SP, Liu AY, Avila S, Tao R, Holliday EB, Brownlee Z, Kaseb A, Lee S, Raghav K, Vauthey JN, Minsky BD, Herman JM, Das P, Smith GL, Taniguchi CM, Krishnan S, Crane CH, Grassberger C, Hong TS, Lin SH, Koong AC, Mohan R, Koay EJ

Journal of Hepatocellular Carcinoma 2021, 8:57-69

Published Date: 3 March 2021

Review

Mechanisms Underlying Hepatocellular Carcinoma Progression in Patients with Type 2 Diabetes

Shi T, Kobara H, Oura K, Masaki T

Journal of Hepatocellular Carcinoma 2021, 8:45-55

Published Date: 11 February 2021

Original Research

Efficacy of Local Therapy for Oligometastatic Hepatocellular Carcinoma: A Propensity Score Matched Analysis

Kim K, Kim TH, Kim TH, Seong J

Journal of Hepatocellular Carcinoma 2021, 8:35-44

Published Date: 11 February 2021

Original Research

The Significance of Gamma-Glutamyl Transpeptidase to Lymphocyte Count Ratio in the Early Postoperative Recurrence Monitoring and Prognosis Prediction of AFP-Negative Hepatocellular Carcinoma

Li S, Xu W, Liao M, Zhou Y, Weng J, Ren L, Yu J, Liao W, Huang Z

Journal of Hepatocellular Carcinoma 2021, 8:23-33

Published Date: 9 February 2021

Perspectives

Targeting De Novo Lipogenesis and Cholesterol Biosynthesis Simultaneously is a Novel Therapeutic Option for Hepatocellular Carcinoma

Liu Q, Dong X

Journal of Hepatocellular Carcinoma 2021, 8:19-21

Published Date: 28 January 2021

Review

Recent Update on the Role of Circular RNAs in Hepatocellular Carcinoma

Ely A, Bloom K, Maepa MB, Arbuthnot P

Journal of Hepatocellular Carcinoma 2021, 8:1-17

Published Date: 27 January 2021

Original Research

Effect of Inhibiting Tumor Angiogenesis After Embolization in the Treatment of HCC with Apatinib-Loaded p(N-Isopropyl-Acrylamide-co-Butyl Methyl Acrylate) Temperature-Sensitive Nanogel

Zhou C, Shi Q, Liu J, Huang S, Yang C, Xiong B

Journal of Hepatocellular Carcinoma 2020, 7:447-456

Published Date: 31 December 2020

Review

Efficacy of Local Treatments for Hepatocellular Carcinoma Involving the Inferior Vena Cava and/or Right Atrium

Lee HA, Rim CH

Journal of Hepatocellular Carcinoma 2020, 7:435-446

Published Date: 21 December 2020

Expert Opinion

Potential Impact of IMbrave150 Results in the Evolving Treatment Landscape of Advanced Hepatocellular Carcinoma: A Multidisciplinary Expert Opinion

Kulik L, da Fonseca LG, He AR, Rimola J, Wilson Woods A, Zöllner YF, Galle PR

Journal of Hepatocellular Carcinoma 2020, 7:423-433

Published Date: 21 December 2020

Review

Serum Tumor Markers for Early Diagnosis of Primary Hepatocellular Carcinoma

Zong J, Fan Z, Zhang Y

Journal of Hepatocellular Carcinoma 2020, 7:413-422

Published Date: 18 December 2020

Original Research

Appraisal of Long-Term Outcomes of Liver-Directed Concurrent Chemoradiotherapy for Hepatocellular Carcinoma with Major Portal Vein Invasion

Han S, Lee HW, Park JY, Kim SU, Kim DY, Ahn SH, Han KH, Seong J, Won JY, Han DH, Kim BK

Journal of Hepatocellular Carcinoma 2020, 7:403-412

Published Date: 17 December 2020

Original Research

Increased Expression of Programmed Death Ligand 1 in Hepatocellular Carcinoma of Patients with Hepatitis B Virus Pre-S2 Mutant

Teng CF, Li TC, Wang T, Wu TH, Wang J, Wu HC, Shyu WC, Su IJ, Jeng LB

Journal of Hepatocellular Carcinoma 2020, 7:385-401

Published Date: 17 December 2020

Original Research

Can Immediately Treating Subcentimeter Hepatocellular Carcinoma Improve the Survival of Patients?

Sun X, Hu D, Zhang Y, Lyu N, Xu L, Chen Q, Lai J, Chen M, Zhao M

Journal of Hepatocellular Carcinoma 2020, 7:377-384

Published Date: 16 December 2020

Original Research

Effects of LRP1B Regulated by HSF1 on Lipid Metabolism in Hepatocellular Carcinoma

Li M, Hu J, Jin R, Cheng H, Chen H, Li L, Guo K

Journal of Hepatocellular Carcinoma 2020, 7:361-376

Published Date: 8 December 2020

Review

Timing of DAA Initiation After Curative Treatment and Its Relationship with the Recurrence of HCV-Related HCC

Gao X, Zhan M, Wang L, Ding Y, Niu J

Journal of Hepatocellular Carcinoma 2020, 7:347-360

Published Date: 1 December 2020

Original Research

Baseline HBV Loads Do Not Affect the Prognosis of Patients with Hepatocellular Carcinoma Receiving Anti-Programmed Cell Death-1 Immunotherapy

Sun X, Hu D, Yang Z, Liu Z, Wang J, Chen J, Xu L, Zhou Z, Chen M, Zhang Y

Journal of Hepatocellular Carcinoma 2020, 7:337-345

Published Date: 1 December 2020

Original Research

Value of Follow-Up Chest Computed Tomography in the Surveillance of Patients with Hepatocellular Carcinoma

Moawad AW, Elsayes KM, Benamar F, Rao K, Sun J, Szklaruk J

Journal of Hepatocellular Carcinoma 2020, 7:331-335

Published Date: 18 November 2020

Original Research

Development and Verification of the Hypoxia-Related and Immune-Associated Prognosis Signature for Hepatocellular Carcinoma

Hu B, Yang XB, Sang XT

Journal of Hepatocellular Carcinoma 2020, 7:315-330

Published Date: 11 November 2020

Original Research

Cross-Linked Multimeric Pro-Peptides of Type III Collagen (PC3X) in Hepatocellular Carcinoma – A Biomarker That Provides Additional Prognostic Value in AFP Positive Patients

Jensen C, Holm Nielsen S, Eslam M, Genovese F, Nielsen MJ, Vongsuvanh R, Uchila R, van der Poorten D, George J, Karsdal MA, Leeming DJ, Willumsen N

Journal of Hepatocellular Carcinoma 2020, 7:301-313

Published Date: 9 November 2020

Original Research

Association of the Pretreatment Lung Immune Prognostic Index with Survival Outcomes in Advanced Hepatocellular Carcinoma Patients Treated with PD-1 Inhibitors

Chen S, Huang Z, Jia W, Tao H, Zhang S, Ma J, Liu Z, Wang J, Wang L, Cui P, Zhang Z, Huang D, Wu Z, Zheng X, Hu Y

Journal of Hepatocellular Carcinoma 2020, 7:289-299

Published Date: 2 November 2020

Review

Gut Microbiota, Peroxisome Proliferator-Activated Receptors, and Hepatocellular Carcinoma

Yu Q, Wu L, Ji J, Feng J, Dai W, Li J, Wu J, Guo C

Journal of Hepatocellular Carcinoma 2020, 7:271-288

Published Date: 29 October 2020

Original Research

miR-3 Encoded by Hepatitis B Virus Downregulates PTEN Protein Expression and Promotes Cell Proliferation

Tang J, Xiao XQ, Jiang Y, Tian Y, Peng Z, Yang M, Xu Z, Gong G

Journal of Hepatocellular Carcinoma 2020, 7:257-269

Published Date: 29 October 2020

Original Research

Prognostic Nomograms for Patients with Hepatocellular Carcinoma After Curative Hepatectomy, with a Focus on Recurrence Timing and Post-Recurrence Management

Xu W, Liu F, Shen X, Li R

Journal of Hepatocellular Carcinoma 2020, 7:233-256

Published Date: 27 October 2020

Original Research

Validation of the GALAD Model and Establishment of GAAP Model for Diagnosis of Hepatocellular Carcinoma in Chinese Patients

Liu M, Wu R, Liu X, Xu H, Chi X, Wang X, Zhan M, Wang B, Peng F, Gao X, Shi Y, Wen X, Ji Y, Jin Q, Niu J

Journal of Hepatocellular Carcinoma 2020, 7:219-232

Published Date: 23 October 2020

Original Research

Assessing the Survival Benefit of Surgery and Various Types of Radiation Therapy for Treatment of Hepatocellular Carcinoma: Evidence from the Surveillance, Epidemiology, and End Results Registries

Shi F, Wang C, Kong Y, Yang L, Li J, Zhu G, Guo J, Zheng Q, Zhang B, Wang S

Journal of Hepatocellular Carcinoma 2020, 7:201-218

Published Date: 19 October 2020

Original Research

Elevated Platelet Count is Associated with Poor Survival After Transarterial Chemoembolization Treatment in Patients with Hepatocellular Carcinoma: A Cohort Study

Lu L, Zhang Y, Zheng P, Wu Z, Wang X, Chen Y, Chen X

Journal of Hepatocellular Carcinoma 2020, 7:191-199

Published Date: 15 October 2020

Original Research

Drug-eluting Bead-Transcatheter Arterial Chemoembolization for Advanced Hepatocellular Carcinoma Refractory to Conventional Lipiodol-based Transcatheter Arterial Chemoembolization

Kobayashi S, Tajiri K, Murayama A, Entani T, Futsukaichi Y, Nagata K, Takahashi K, Yasuda I

Journal of Hepatocellular Carcinoma 2020, 7:181-189

Published Date: 14 October 2020

Original Research

The Clinicopathological and Imaging Characteristics of Primary Hepatic Carcinosarcoma and a Review of the Literature

Bin F, Chen Z, Liu P, Liu J, Mao Z

Journal of Hepatocellular Carcinoma 2020, 7:169-180

Published Date: 13 October 2020

Original Research

Amide Proton Transfer Imaging vs Diffusion Kurtosis Imaging for Predicting Histological Grade of Hepatocellular Carcinoma

Wu B, Jia F, Li X, Zhang M, Han D, Jia Z

Journal of Hepatocellular Carcinoma 2020, 7:159-168

Published Date: 9 October 2020

Expert Opinion

Surgical Management of Localized Hepatocellular Carcinoma in Times of Crisis: A Strategic Approach to Resource Utilization

Tran Cao H, Tzeng CW, Chun YS, Aloia T, Vauthey JN

Journal of Hepatocellular Carcinoma 2020, 7:155-158

Published Date: 28 September 2020

Original Research

Prognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study

Lacin S, Yalcin S, Karakas Y, Hassan MM, Amin H, Mohamed YI, Rashid A, Morris JS, Xiao L, Qayyum A, Kaseb AO

Journal of Hepatocellular Carcinoma 2020, 7:143-153

Published Date: 16 September 2020

Review

Combination Antiangiogenic and Immunotherapy for Advanced Hepatocellular Carcinoma: Evidence to Date

Raybould AL, Sanoff H

Journal of Hepatocellular Carcinoma 2020, 7:133-142

Published Date: 15 September 2020

Original Research

Survival Outcomes for Yttrium-90 Transarterial Radioembolization With and Without Sorafenib for Unresectable Hepatocellular Carcinoma Patients

Teyateeti A, Mahvash A, Long JP, Abdelsalam ME, Avritscher R, Chasen B, Kaseb AO, Kuban JD, Murthy R, Odisio BC, Teyateeti A, Macapinlac HA, Kappadath SC

Journal of Hepatocellular Carcinoma 2020, 7:117-131

Published Date: 14 September 2020

Review

Resection of NAFLD-Associated HCC: Patient Selection and Reported Outcomes

Campani C, Bensi C, Milani S, Galli A, Tarocchi M

Journal of Hepatocellular Carcinoma 2020, 7:107-116

Published Date: 30 July 2020

Original Research

Inflammation-Based Prognostic Scores in Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma After Liver Transplantation

Ren A, Li Z, Zhang X, Deng R, Ma Y

Journal of Hepatocellular Carcinoma 2020, 7:101-106

Published Date: 7 July 2020

Review

Profile of Cabozantinib for the Treatment of Hepatocellular Carcinoma: Patient Selection and Special Considerations

Debaillon Vesque A, Decraecker M, Blanc JF

Journal of Hepatocellular Carcinoma 2020, 7:91-99

Published Date: 9 June 2020

Review

Angiogenesis in Hepatocellular Carcinoma; Pathophysiology, Targeted Therapy, and Role of Imaging

Moawad AW, Szklaruk J, Lall C, Blair KJ, Kaseb AO, Kamath A, Rohren SA, Elsayes KM

Journal of Hepatocellular Carcinoma 2020, 7:77-89

Published Date: 23 April 2020

Review

Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment

Dash S, Aydin Y, Widmer KE, Nayak L

Journal of Hepatocellular Carcinoma 2020, 7:45-76

Published Date: 15 April 2020

Case report

Rare Site Hepatocellular Carcinoma Metastasis

Boldo E, Santafe A, Mayol A, Lozoya R, Coret A, Escribano D, Fortea-Sanchis C, Muñoz A, Pastor JC, Perez de Lucia G, Bosch N

Journal of Hepatocellular Carcinoma 2020, 7:39-44

Published Date: 25 March 2020

Review

Impact of Next-Generation Sequencing on Outcomes in Hepatocellular Carcinoma: How Precise Are We Really?

Dominguez DA, Wang XW

Journal of Hepatocellular Carcinoma 2020, 7:33-37

Published Date: 19 March 2020

Original Research

Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2

Liu T, Li S, Wu L, Yu Q, Li J, Feng J, Zhang J, Chen J, Zhou Y, Ji J, Chen K, Mao Y, Wang F, Dai W, Fan X, Wu J, Guo C

Journal of Hepatocellular Carcinoma 2020, 7:19-31

Published Date: 18 February 2020

Review

The Immune Modulation Effect of Locoregional Therapies and Its Potential Synergy with Immunotherapy in Hepatocellular Carcinoma

Singh P, Toom S, Avula A, Kumar V, Rahma OE

Journal of Hepatocellular Carcinoma 2020, 7:11-17

Published Date: 10 February 2020

Original Research

Exploring Metabolic Consequences of CPS1 and CAD Dysregulation in Hepatocellular Carcinoma by Network Reconstruction

Dumenci OE, U AMR, Khan SA, Holmes E, Taylor-Robinson SD

Journal of Hepatocellular Carcinoma 2020, 7:1-9

Published Date: 7 January 2020

Review

Hepatitis C Antiviral Therapy In Patients With Successfully Treated Hepatocellular Carcinoma: Dancing With Wolves

El Kassas M, Tawheed A, Eltabbakh M, Kaseb A

Journal of Hepatocellular Carcinoma 2019, 6:183-191

Published Date: 19 November 2019

Original Research

Socioeconomic And Survival Differences Among Minorities With Hepatocellular Carcinoma In Florida

Jones PD, Scheinberg AR, Muenyi V, Gonzalez-Diaz J, Martin PM, Kobetz E

Journal of Hepatocellular Carcinoma 2019, 6:167-181

Published Date: 15 November 2019

Review

Genetic Biomarkers For Hepatocellular Carcinoma In The Era Of Precision Medicine

Duan J, Wu Y, Liu J, Zhang J, Fu Z, Feng T, Liu M, Han J, Li Z, Chen S

Journal of Hepatocellular Carcinoma 2019, 6:151-166

Published Date: 18 October 2019

Original Research

Hepatitis B And Hepatitis C Viral Infections And Associated Factors Among Patients With Diabetes Visiting Gondar Referral Teaching Hospital, Northwest Ethiopia: A Comparative Cross-Sectional Study

Million Y, Teklu T, Alemu S, Ferede A, Belachew T, Desta K

Journal of Hepatocellular Carcinoma 2019, 6:143-150

Published Date: 8 October 2019

Review

Status of, and strategies for improving, adherence to HCC screening and surveillance

Francica G, Borzio M

Journal of Hepatocellular Carcinoma 2019, 6:131-141

Published Date: 24 July 2019

Original Research

Clinical outcomes of rare hepatocellular carcinoma variants compared to pure hepatocellular carcinoma

Zakka K, Jiang R, Alese OB, Shaib WL, Wu C, Wedd JP, Sellers MT, Behera M, El-Rayes BF, Akce M

Journal of Hepatocellular Carcinoma 2019, 6:119-129

Published Date: 22 July 2019

Review

Intermediate stage hepatocellular carcinoma: a summary review

Elshaarawy O, Gomaa A, Omar H, Rewisha E, Waked I

Journal of Hepatocellular Carcinoma 2019, 6:105-117

Published Date: 11 July 2019

Original Research

Prospective Phase II trial of drug-eluting bead chemoembolization for liver transplant candidates with hepatocellular carcinoma and marginal hepatic reserve

Fidelman N, Johanson C, Kohi MP, Kolli KP, Kohlbrenner RM, Lehrman ED, Taylor AG, Kelley RK, Yao FY, Roberts JP, Kerlan RK

Journal of Hepatocellular Carcinoma 2019, 6:93-103

Published Date: 17 June 2019

Review

Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma

Delgado TC, Lopitz-Otsoa F, Martínez-Chantar ML

Journal of Hepatocellular Carcinoma 2019, 6:85-91

Published Date: 6 June 2019

Review

Targeting myeloid-derived suppressor cells in the treatment of hepatocellular carcinoma: current state and future perspectives

Lu LC, Chang CJ, Hsu CH

Journal of Hepatocellular Carcinoma 2019, 6:71-84

Published Date: 7 May 2019

Review

LI-RADS: a conceptual and historical review from its beginning to its recent integration into AASLD clinical practice guidance

Elsayes KM, Kielar AZ, Chernyak V, Morshid A, Furlan A, Masch WR, Marks RM, Kamaya A, Do RKG, Kono Y, Fowler KJ, Tang A, Bashir MR, Hecht EM, Jambhekar K, Lyshchik A, Rodgers SK, Heiken JP, Kohli M, Fetzer DT, Wilson SR, Kassam Z, Mendiratta-Lala M, Singal AG, Lim CS, Cruite I, Lee J, Ash R, Mitchell DG, McInnes MDF, Sirlin CB

Journal of Hepatocellular Carcinoma 2019, 6:49-69

Published Date: 5 February 2019

Meeting Report

Road map for fibrolamellar carcinoma: progress and goals of a diversified approach

Kastenhuber ER, Craig J, Ramsey J, Sullivan KM, Sage J, de Oliveira S, Riehle KJ, Scott JD, Gordan JD, Bardeesy N, Abou-Alfa GK

Journal of Hepatocellular Carcinoma 2019, 6:41-48

Published Date: 31 January 2019

Review

Lenvatinib for the treatment of unresectable hepatocellular carcinoma: evidence to date

Personeni N, Pressiani T, Rimassa L

Journal of Hepatocellular Carcinoma 2019, 6:31-39

Published Date: 31 January 2019

Review

Weighing the benefits of hepatocellular carcinoma surveillance against potential harms

Geh D, Rana FA, Reeves HL

Journal of Hepatocellular Carcinoma 2019, 6:23-30

Published Date: 14 January 2019

Review

Combined hepatocellular cholangiocarcinoma (cHCC-CC): an update of genetics, molecular biology, and therapeutic interventions

Stavraka C, Rush H, Ross P

Journal of Hepatocellular Carcinoma 2019, 6:11-21

Published Date: 28 December 2018

Review

Selecting patients with hepatocellular carcinoma for liver transplantation: incorporating tumor biology criteria

Amado V, Rodríguez-Perálvarez M, Ferrín G, De la Mata M

Journal of Hepatocellular Carcinoma 2019, 6:1-10

Published Date: 21 December 2018

Original Research

Sorafenib plus tegafur–uracil (UFT) versus sorafenib as first line systemic treatment for patients with advanced stage HCC: a Phase II trial (ESLC01 study)

Azim HA, Omar A, Atef H, Zawahry H, Shaker MK, Abdelmaksoud AHK, EzzElarab M, Abdel-Rahman O, Ismail M, Kassem L, Waked I

Journal of Hepatocellular Carcinoma 2018, 5:109-119

Published Date: 19 November 2018

Review

Hepatocellular carcinoma: a review of diagnostic challenges for the pathologist

Quaglia A

Journal of Hepatocellular Carcinoma 2018, 5:99-108

Published Date: 8 November 2018

Review

Potential of ramucirumab in treating hepatocellular carcinoma patients with elevated baseline alpha-fetoprotein

Gilabert M, Raoul JL

Journal of Hepatocellular Carcinoma 2018, 5:91-98

Published Date: 2 November 2018

Review

Update on hepatocellular carcinoma from the 2018 Gastrointestinal Cancer Symposium (ASCO GI)

de Jesus VHF, Dettino ALA

Journal of Hepatocellular Carcinoma 2018, 5:87-90

Published Date: 3 October 2018

Original Research

Hepatitis C virus-associated hepatocellular carcinoma as a second primary malignancy: exposing an overlooked presentation of liver cancer

Dandachi D, Hassan M, Kaseb A, Angelidakis G, Torres HA

Journal of Hepatocellular Carcinoma 2018, 5:81-86

Published Date: 2 August 2018

Review

Hepatocellular cancer pain: impact and management challenges

Christian-Miller N, Frenette C

Journal of Hepatocellular Carcinoma 2018, 5:75-80

Published Date: 19 July 2018

Review

Role of Wnt/β-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance

Khalaf AM, Fuentes D, Morshid AI, Burke MR, Kaseb AO, Hassan M, Hazle JD, Elsayes KM

Journal of Hepatocellular Carcinoma 2018, 5:61-73

Published Date: 27 June 2018

Case Series

Decreased hepatocellular carcinoma tumor burden with the achievement of hepatitis C virus sustained virologic response: unlocking the potential of T-cell-mediated immunosurveillance

Griffith AS, Hayashi PH, Burke LMB, McRee AJ

Journal of Hepatocellular Carcinoma 2018, 5:55-59

Published Date: 31 May 2018

Editorial

Editorial: charting the future of hepatocellular carcinoma publications

Kaseb AO

Journal of Hepatocellular Carcinoma 2018, 5:51-54

Published Date: 8 May 2018

Review

Basic MRI for the liver oncologists and surgeons

Vu LN, Morelli JN, Szklaruk J

Journal of Hepatocellular Carcinoma 2018, 5:37-50

Published Date: 10 April 2018

Clinical Trial Report

Efficacy of loco-regional treatment for hepatocellular carcinoma prior to living donor liver transplantation: a report from a single center in Egypt

Shaker MK, Montasser IF, Sakr M, Elgharib M, Dabbous HM, Ebada H, El Dorry A, Bahaa M, El Meteini M

Journal of Hepatocellular Carcinoma 2018, 5:29-36

Published Date: 27 February 2018

Review

Pretreatment neutrophil–lymphocyte ratio: useful prognostic biomarker in hepatocellular carcinoma

Najjar M, Agrawal S, Emond JC, Halazun KJ

Journal of Hepatocellular Carcinoma 2018, 5:17-28

Published Date: 18 January 2018

Original Research

Phase II trial of SOM230 (pasireotide LAR) in patients with unresectable hepatocellular carcinoma

Feun LG, Wangpaichitr M, Li YY, Kwon D, Richman SP, Hosein PJ, Savaraj N

Journal of Hepatocellular Carcinoma 2018, 5:9-15

Published Date: 12 January 2018

Original Research

Liver resection versus radiofrequency ablation for hepatitis B virus-related small hepatocellular carcinoma

Liang B, Yao SY, Zhou JP, Li ZK, Liu TQ

Journal of Hepatocellular Carcinoma 2018, 5:1-7

Published Date: 12 January 2018

Original Research

Characterization of alpha-fetoprotein effects on dendritic cell and its function as effector immune response activator

Suryatenggara J, Wibowo H, Atmodjo WL, Mathew G

Journal of Hepatocellular Carcinoma 2017, 4:139-151

Published Date: 28 November 2017

Review

Optimal therapy for patients with hepatocellular carcinoma and resistance or intolerance to sorafenib: challenges and solutions

Ray EM, Sanoff HK

Journal of Hepatocellular Carcinoma 2017, 4:131-138

Published Date: 8 November 2017

Original Research

Healthcare costs of transarterial chemoembolization in the treatment of hepatocellular carcinoma

Fateen W, Khan F, O’Neill RJ, James MW, Ryder SD, Aithal GP

Journal of Hepatocellular Carcinoma 2017, 4:123-130

Published Date: 16 October 2017

Clinical Trial Report

A Phase I trial using local regional treatment, nonlethal irradiation, intratumoral and systemic polyinosinic-polycytidylic acid polylysine carboxymethylcellulose to treat liver cancer: in search of the abscopal effect

de la Torre AN, Contractor S, Castaneda I, Cathcart CS, Razdan D, Klyde D, Kisza P, Gonzales SF, Salazar AM

Journal of Hepatocellular Carcinoma 2017, 4:111-121

Published Date: 7 August 2017

Review

Transarterial chemoembolization for the treatment of hepatocellular carcinoma: a review

Sacco R, Tapete G, Simonetti N, Sellitri R, Natali V, Melissari S, Cabibbo G, Biscaglia L, Bresci G, Giacomelli L

Journal of Hepatocellular Carcinoma 2017, 4:105-110

Published Date: 27 July 2017

Review

Targeted therapy and personalized medicine in hepatocellular carcinoma: drug resistance, mechanisms, and treatment strategies

Galun D, Srdic-Rajic T, Bogdanovic A, Loncar Z, Zuvela M

Journal of Hepatocellular Carcinoma 2017, 4:93-103

Published Date: 11 July 2017

Review

Hepatocellular carcinoma: early-stage management challenges

Erstad DJ, Tanabe KK

Journal of Hepatocellular Carcinoma 2017, 4:81-92

Published Date: 23 June 2017

Review

Screening for hepatocellular carcinoma: patient selection and perspectives

Fateen W, Ryder SD

Journal of Hepatocellular Carcinoma 2017, 4:71-79

Published Date: 17 May 2017

Clinical Trial Report

Open-label phase II clinical trial in 75 patients with advanced hepatocellular carcinoma receiving daily dose of tableted liver cancer vaccine, hepcortespenlisimut-L

Tarakanovskaya MG, Chinburen J, Batchuluun P, Munkhzaya C, Purevsuren G, Dandii D, Hulan T, Oyungerel D, Kutsyna GA, Reid AA, Borisova V, Bain AI, Jirathitikal V, Bourinbaiar AS

Journal of Hepatocellular Carcinoma 2017, 4:59-69

Published Date: 12 April 2017

Review

Irreversible electroporation of hepatocellular carcinoma: patient selection and perspectives

Zimmerman A, Grand D, Charpentier KP

Journal of Hepatocellular Carcinoma 2017, 4:49-58

Published Date: 13 March 2017

Case Series

A single institution report of 19 hepatocellular carcinoma patients with bile duct tumor thrombus

Chotirosniramit A, Liwattanakun A, Lapisatepun W, Ko-iam W, Sandhu T, Junrungsee S

Journal of Hepatocellular Carcinoma 2017, 4:41-47

Published Date: 7 March 2017

Expert Opinion

Liver Imaging Reporting and Data System: an expert consensus statement

Elsayes KM, Kielar AZ, Agrons MM, Szklaruk J, Tang A, Bashir MR, Mitchell DG, Do RK, Fowler KJ, Chernyak V, Sirlin CB

Journal of Hepatocellular Carcinoma 2017, 4:29-39

Published Date: 17 February 2017

Review

Needle track seeding after radiofrequency ablation for hepatocellular carcinoma: prevalence, impact, and management challenge

Francica G

Journal of Hepatocellular Carcinoma 2017, 4:23-27

Published Date: 20 January 2017

Review

Pediatric hepatocellular carcinoma: challenges and solutions

Schmid I, von Schweinitz D

Journal of Hepatocellular Carcinoma 2017, 4:15-21

Published Date: 16 January 2017

Commentary

Strengthening the case that elevated levels of programmed death ligand 1 predict poor prognosis in hepatocellular carcinoma patients

Zhong J, Luo C, Zhang C, Li L

Journal of Hepatocellular Carcinoma 2017, 4:11-13

Published Date: 30 December 2016

Review

Surgical resection of localized hepatocellular carcinoma: patient selection and special consideration

Ma KW, Cheung TT

Journal of Hepatocellular Carcinoma 2017, 4:1-9

Published Date: 28 December 2016

Review

Profile of tivantinib and its potential in the treatment of hepatocellular carcinoma: the evidence to date

Pievsky D, Pyrsopoulos N

Journal of Hepatocellular Carcinoma 2016, 3:69-76

Published Date: 15 November 2016

Review

GPC-3 in hepatocellular carcinoma: current perspectives

Wu Y, Liu H, Ding H

Journal of Hepatocellular Carcinoma 2016, 3:63-67

Published Date: 8 November 2016

Review

Minimally invasive image-guided therapies for hepatocellular carcinoma

Abdelsalam ME, Murthy R, Avritscher R, Mahvash A, Wallace MJ, Kaseb AO, Odisio BC

Journal of Hepatocellular Carcinoma 2016, 3:55-61

Published Date: 11 October 2016

Review

Hepatocellular carcinoma: a review

Balogh J, Victor III D, Asham EH, Burroughs SG, Boktour M, Saharia A, Li X, Ghobrial RM, Monsour Jr HP

Journal of Hepatocellular Carcinoma 2016, 3:41-53

Published Date: 5 October 2016

Commentary

Does alpha-fetoprotein contribute to the mortality and morbidity of human hepatocellular carcinoma? A commentary

Mizejewski GJ

Journal of Hepatocellular Carcinoma 2016, 3:37-40

Published Date: 21 September 2016

Review

Role of regorafenib as second-line therapy and landscape of investigational treatment options in advanced hepatocellular carcinoma

Trojan J, Waidmann O

Journal of Hepatocellular Carcinoma 2016, 3:31-36

Published Date: 21 September 2016

Review

Transarterial radioembolization for hepatocellular carcinoma: a review

Sacco R, Conte C, Tumino E, Parisi G, Marceglia S, Metrangolo S, Eggenhoffner R, Bresci G, Cabibbo G, Giacomelli L

Journal of Hepatocellular Carcinoma 2016, 3:25-29

Published Date: 25 July 2016

Original Research

Clinical significance of vascular endothelial growth factor in hepatitis C related hepatocellular carcinoma in Egyptian patients

Atta MM, Atta HM, Gad MA, Rashed LA, Said EM, Hassanien SE, Kaseb AO

Journal of Hepatocellular Carcinoma 2016, 3:19-24

Published Date: 14 June 2016

Review

Hepatocellular carcinoma in elderly patients: challenges and solutions

Brunot A, Le Sourd S, Pracht M, Edeline J

Journal of Hepatocellular Carcinoma 2016, 3:9-18

Published Date: 17 June 2016

Original Research

Yttrium-90 resin microspheres as an adjunct to sorafenib in patients with unresectable hepatocellular carcinoma

Mahvash A, Murthy R, Odisio BC, Raghav KP, Girard L, Cheung S, Nguyen V, Ensor J, Gadani S, Elsayes KM, Abdel-Wahab R, Hassan M, Shalaby AS, Yao JC, Wallace MJ, Kaseb AO

Journal of Hepatocellular Carcinoma 2016, 3:1-7

Published Date: 5 February 2016

Review

Fibrolamellar hepatocellular carcinoma: current clinical perspectives

Lafaro KJ, Pawlik TM

Journal of Hepatocellular Carcinoma 2015, 2:151-157

Published Date: 9 October 2015

Review

Role of endoscopic ultrasound in diagnosis and management of hepatocellular carcinoma

Koduru P, Suzuki R, Lakhtakia S, Ramchandani M, Makmun D, Bhutani MS

Journal of Hepatocellular Carcinoma 2015, 2:143-149

Published Date: 6 October 2015

Review

Type I insulin-like growth factor as a liver reserve assessment tool in hepatocellular carcinoma

Abdel-Wahab R, Shehata S, Hassan MM, Habra MA, Eskandari G, Tinkey PT, Mitchell J, Lee JS, Amin HM, Kaseb AO

Journal of Hepatocellular Carcinoma 2015, 2:131-142

Published Date: 18 September 2015

Review

Transarterial chemoembolization for hepatocellular carcinoma: an evidence-based review of its place in therapy

Jang JH, Lee JW, Hong JT, Jin YJ

Journal of Hepatocellular Carcinoma 2015, 2:123-129

Published Date: 2 September 2015

Editorial

Whither α-FP in the diagnosis of hepatocellular carcinoma?

Kew MC

Journal of Hepatocellular Carcinoma 2015, 2:119-121

Published Date: 24 August 2015

Review

State-of-the-art cross-sectional liver imaging: beyond lesion detection and characterization

Luersen GF, Bhosale P, Szklaruk J

Journal of Hepatocellular Carcinoma 2015, 2:101-117

Published Date: 10 July 2015

Review

The androgen receptor as an emerging target in hepatocellular carcinoma

Kanda T, Yokosuka O

Journal of Hepatocellular Carcinoma 2015, 2:91-99

Published Date: 26 June 2015

Original Research

Ambovex® as a novel immunological modulator drug for the treatment of hepatocellular carcinoma (HCC) in the liver: a Phase II clinical trial

Salama H, Ahmad H, Elchagea I, Zekri AR, Medhat E, Bahnassy A, Lange M, Rabbat M, de la Torre AN, Punamiya P

Journal of Hepatocellular Carcinoma 2015, 2:79-89

Published Date: 22 June 2015

Review

Emerging role of Hpo signaling and YAP in hepatocellular carcinoma

Valero V III, Pawlik TM, Anders RA

Journal of Hepatocellular Carcinoma 2015, 2:69-78

Published Date: 18 June 2015

Original Research

Hapten-enhanced overall survival time in advanced hepatocellular carcinoma by ultro-minimum incision personalized intratumoral chemoimmunotherapy

Gao F, Jing P, Liu J, Lu YF, Zhang PC, Han W, Liu GL, Ru N, Cui GH, Sun CL, Che YB, Zhang HM, Hu QL, Wang HY, Wu YL, Guan CJ, Fu Q, Ma ZL, Yu BF

Journal of Hepatocellular Carcinoma 2015, 2:57-68

Published Date: 9 June 2015

Editorial

Hepatocellular carcinoma ablation and possible immunity in the age of nanosecond pulsed electric fields

Beebe SJ

Journal of Hepatocellular Carcinoma 2015, 2:49-55

Published Date: 22 May 2015

Original Research

Early α-fetoprotein response predicts survival in patients with advanced hepatocellular carcinoma treated with sorafenib

Lee SH, Kim BK, Kim SU, Park JY, Kim DY, Ahn SH, Han KH

Journal of Hepatocellular Carcinoma 2015, 2:39-47

Published Date: 28 April 2015

Review

c-MET receptor tyrosine kinase as a molecular target in advanced hepatocellular carcinoma

Granito A, Guidetti E, Gramantieri L

Journal of Hepatocellular Carcinoma 2015, 2:29-38

Published Date: 24 April 2015

Review

A clinical perspective of the link between metabolic syndrome and hepatocellular carcinoma

Cauchy F, Belghiti J

Journal of Hepatocellular Carcinoma 2015, 2:19-27

Published Date: 23 February 2015

Review

Emerging role of Toll-like receptor 4 in hepatocellular carcinoma

Yang J, Li M, Zheng QC

Journal of Hepatocellular Carcinoma 2015, 2:11-17

Published Date: 16 February 2015

Original Research

Untreated hepatocellular carcinoma in Egypt: outcome and prognostic factors

Zeeneldin AA, Salem SE, Darwish AD, El-Gammal MM, Hussein MM, Saadeldin M

Journal of Hepatocellular Carcinoma 2015, 2:3-9

Published Date: 30 January 2015

Editorial

Welcome to Journal of Hepatocellular Carcinoma

Kaseb AO

Journal of Hepatocellular Carcinoma 2015, 2:1-2

Published Date: 9 January 2015

Original Research

Chemoembolization with drug-eluting microspheres (DEM-TACE) for hepatocellular carcinoma: single-center review of safety and efficacy

Bishay VL, Maglione K, Khanna R, Lee KM, Fischman AM, Lookstein RA, Kim E

Journal of Hepatocellular Carcinoma 2014, 1:187-193

Published Date: 27 November 2014

Review

Emerging role of dual antiplatelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma

Aiolfi R, Sitia G

Journal of Hepatocellular Carcinoma 2014, 1:183-186

Published Date: 13 November 2014

Review

Transarterial radioembolization using yttrium-90 microspheres in the treatment of hepatocellular carcinoma: a review on clinical utility and developments

Cappelli A, Pettinato C, Golfieri R

Journal of Hepatocellular Carcinoma 2014, 1:163-182

Published Date: 3 November 2014

Original Research

Potent efficacy signals from systemically administered oncolytic herpes simplex virus (HSV1716) in hepatocellular carcinoma xenograft models

Braidwood L, Learmonth K, Graham A, Conner J

Journal of Hepatocellular Carcinoma 2014, 1:149-161

Published Date: 16 October 2014

Review

Radiological diagnosis of hepatocellular carcinoma

Bargellini I, Battaglia V, Bozzi E, Lauretti DL, Lorenzoni G, Bartolozzi C

Journal of Hepatocellular Carcinoma 2014, 1:137-148

Published Date: 9 September 2014

Review

Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinoma

Hsu HT, Chi CW

Journal of Hepatocellular Carcinoma 2014, 1:127-135

Published Date: 26 August 2014

Review

Hepatocellular carcinoma: epidemiology and risk factors

Kew MC

Journal of Hepatocellular Carcinoma 2014, 1:115-125

Published Date: 13 August 2014

Case Series

Telaprevir-containing regimen for treatment of hepatitis C virus infection in patients with hepatocellular carcinoma awaiting liver transplantation: a case series

Torres HA, Kaseb A, Mahale P, Miller E, Frenette C

Journal of Hepatocellular Carcinoma 2014, 1:109-114

Published Date: 16 July 2014

Review

Clinical utility of imaging for evaluation of hepatocellular carcinoma

Murakami T, Tsurusaki M, Hyodo T, Imai Y

Journal of Hepatocellular Carcinoma 2014, 1:101-108

Published Date: 14 July 2014

Review

Sorafenib in advanced hepatocellular carcinoma: current status and future perspectives

Hsu CH, Shen YC, Shao YY, Hsu C, Cheng AL

Journal of Hepatocellular Carcinoma 2014, 1:85-99

Published Date: 12 June 2014

Review

New insights on the role of epigenetic alterations in hepatocellular carcinoma

Frau M, Feo CF, Feo F, Pascale RM

Journal of Hepatocellular Carcinoma 2014, 1:65-83

Published Date: 12 June 2014

Original Research

Potential immunotherapeutic role of interleukin-2 and interleukin-12 combination in patients with hepatocellular carcinoma

Gabeen AA, Abdel-Hamid FF, El-Houseini ME, Fathy SA

Journal of Hepatocellular Carcinoma 2014, 1:55-63

Published Date: 9 June 2014

Review

Fibroblast growth factor family as a potential target in the treatment of hepatocellular carcinoma

Coleman SJ, Grose RP, Kocher HM

Journal of Hepatocellular Carcinoma 2014, 1:43-54

Published Date: 29 May 2014

Review

Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma

Ofuji K, Saito K, Yoshikawa T, Nakatsura T

Journal of Hepatocellular Carcinoma 2014, 1:35-42

Published Date: 21 May 2014

Review

Micro-ribonucleic acids: potential noninvasive biomarkers for hepatocellular carcinoma

Li L, Diao W, Zen K

Journal of Hepatocellular Carcinoma 2014, 1:21-33

Published Date: 21 May 2014

Review

Emerging role of insulin-like growth factor-binding protein 7 in hepatocellular carcinoma

Akiel M, Rajasekaran D, Gredler R, Siddiq A, Srivastava J, Robertson C, Jariwala NH, Fisher PB, Sarkar D

Journal of Hepatocellular Carcinoma 2014, 1:9-19

Published Date: 26 March 2014

Review

A review on the diagnosis and treatment of hepatocellular carcinoma with a focus on the role of Wnts and the dickkopf family of Wnt inhibitors

Shi J, Keller JM, Zhang J, Keller ET

Journal of Hepatocellular Carcinoma 2014, 1:1-7

Published Date: 6 March 2014