Amirthalingam P, Alarawi FA, Jassas Alagwar LM, Alatawi MS, Saeed Alfahmi Alzahrani MS, A Albalwi AO, Alrashidi A, Elsaid Hamdan AM, Fahad Alqifari S, Alshareef H, Aljabri A, Sirag N, Pakkir Mohamed SH, Ali MAS

Therapeutics and Clinical Risk Management 2026, 22:610579

Published Date: 4 June 2026

Review

Extracellular Vesicle-Based Strategies for the Prevention of Chemotherapy-Induced Cardiotoxicity

Shen Z, Qiu J, Yu W, Chen R, Jiang Y

Therapeutics and Clinical Risk Management 2026, 22:597871

Published Date: 3 June 2026

Original Research

Association Between Insulin Regimen and Cardiovascular Risk in Indonesian Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study

Natsir RM, Halimah E, Diantini A, Levita J

Therapeutics and Clinical Risk Management 2026, 22:611165

Published Date: 3 June 2026

Review

Maternal, Fetal, and Neonatal Outcomes of Additional Dihydroartemisinin-Piperaquine to Trimethoprim-Sulfamethoxazole in Intermittent Preventive Treatment for Malaria in HIV-Positive Pregnancies: A Systematic Review and Meta-Analysis

Yunivita V, Maharani AJ, Bernadus CA, Sinaga EIJ, Simanjuntak ER

Therapeutics and Clinical Risk Management 2026, 22:571864

Published Date: 27 May 2026

Original Research

Real-World Evidence for Combination Sedation: Propofol Plus Dexmedetomidine and Clinical Outcomes in Mechanically Ventilated ICU Patients

Qi J, Gao W, Ni Q, Liang Z, Wang W, Qiao T, Wang B

Therapeutics and Clinical Risk Management 2026, 22:597422

Published Date: 27 May 2026

Original Research

Impact of Early versus Delayed Vasopressin Initiation on 28-Day Mortality in Older Adults with Septic Shock

Liu L, Shi H, Zhang L, Ma J

Therapeutics and Clinical Risk Management 2026, 22:583585

Published Date: 25 May 2026

Review

Exploring the Current Tools for Fall Risk Assessment in Older Adults Across Southeast Asia and the Need for Culturally Adapted Models: A Scoping Review

Dharmansyah D, Rahayuwati L, Pramukti I, Mutyara K

Therapeutics and Clinical Risk Management 2026, 22:611180

Published Date: 21 May 2026

Original Research

The ESINEA Study: A Novel Screening Tool for Identifying Patient Safety Incidents and Adverse Events in Hospitalized Patients–An Index-Date Cohort Evaluation

Dueñas Lopez FC, Fernández-Arroyo García A, Rivera Núñez MA, Díaz-Pollán B, Sobrino Jiménez C, Murillo Gayo C, Mendieta Azcona C, Jiménez Núñez C, Yagüe de Antonio G, Narrillos Martín I, Guijarro Eguinoa J, Ojeda Feo JJ, González de la Viuda MA, Bautista Reina MDC, Fernández Velilla Peña M, Jiménez-Gonzalez M, Duque Alcorta M, Álvarez-Montero M, González Muñoz M, Lorente Romeo M, Buitrago Sánchez NM, Rogozina O, López Ortego P, Pardo Puras R, Torres Santos Olmo RM, Iniesta Pérez S, Chajma Izquierdo S, Martín López S, Del Rosal T, Parra Ramírez P, Villán Villán YF, Martín Vega A, Ramírez E

Therapeutics and Clinical Risk Management 2026, 22:565087

Published Date: 20 May 2026

Review

Adjunctive Cannabidiol for Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis of Randomized Trials Across Syndromes, Formulations, and Dose Ranges

Pratama R, Muhaimin M, Khairinisa MA, Chaerunisaa AY

Therapeutics and Clinical Risk Management 2026, 22:601774

Published Date: 18 May 2026

Original Research

Effects of TUS-NMES Combined with Glucocorticoid on Clinical Outcomes and Rehabilitation Efficacy of Neurosyphilis Patients with Cerebral Infarction

Dai J, He F, Xu Y, Lei N, Zhang D, He W, Zhu F, Chen S, Shan X, Wu M, Zhang X

Therapeutics and Clinical Risk Management 2026, 22:583163

Published Date: 16 May 2026

Original Research

Predicting Sensory Block Level in Caudal Anesthesia Based on Sacral Canal Anatomical Parameters and Height: Development of an Ordinal Logistic Regression Model and Nomogram

Li Z, Wu H, Zhang S, Yu S, Liu L, Liufu N

Therapeutics and Clinical Risk Management 2026, 22:581371

Published Date: 12 May 2026

Original Research

Staged Management of Bone Defects in Chronic Osteomyelitis and Nonunions Using Antibiotic-Loaded Calcium Sulphate-Hydroxyapatite: A Multicenter Retrospective Analysis of 101 Cases

Armbruster J, Mattern N, Lamadé-Dootz F, Steinhausen ES, Reiter G, Dudda M, Grützner PA, Freischmidt H

Therapeutics and Clinical Risk Management 2026, 22:599996

Published Date: 8 May 2026

Review

Mesenchymal Stromal Cells in Knee Osteoarthritis: A Review of Nomenclature, Criteria, and Therapeutic Mechanisms

Lim DH, Lee CC, Park KB

Therapeutics and Clinical Risk Management 2026, 22:594869

Published Date: 7 May 2026

Original Research

Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial

Wang L, Zhou J, Liu Q, Qian K, Wang L, Xie C

Therapeutics and Clinical Risk Management 2026, 22:588126

Published Date: 7 May 2026

Original Research

Outcome of Emergent ABO-Incompatible Liver Transplantation is Acceptable but at the Cost of Higher Diffuse Intrahepatic Biliary Stricture: A Single-Center, Retrospective Study

Liu J, Qi J, Chen Y, Duan X, Yu X, Jin P, Zhang Y, Zhang W

Therapeutics and Clinical Risk Management 2026, 22:567879

Published Date: 5 May 2026

Review

Prevention and Care of Pressure Ulcers in Long-Term Bedridden Adult and Older Adult Patients in the Community: A Systematic Review

Meng L, Banharak S, Sommana C, Ransinyo K, Cheumnok W, Tian J

Therapeutics and Clinical Risk Management 2026, 22:592581

Published Date: 4 May 2026

Original Research

Exploring the Effects of Prone Position Ventilation Combined with Drug on Clinical Outcomes in Neonates with ARDS: A Single-Center Retrospective Cohort Study

Lin C, Huang T, Wu H, Lin Y, Guo C, Li L

Therapeutics and Clinical Risk Management 2026, 22:578819

Published Date: 30 April 2026

Original Research

rs10010131A in WFS1 is Associated with Elevated Serum Urea in Type 2 Diabetes Patients Treated with SGLT2 Inhibitors

Naja K, Elashi AA, Hedaya L, Anwardeen NR, Al-Shafai M, Rizzo M, Elrayess MA

Therapeutics and Clinical Risk Management 2026, 22:578286

Published Date: 28 April 2026

Clinical Trial Report

Camrelizumab Plus Apatinib in Advanced Unresectable Alveolar Soft Part Sarcoma and Undifferentiated Pleomorphic Sarcoma Patients: A Single-Center, Exploratory Case Series

Tan H, Wang H, Zhou J, Jiang L, Shi S, Wang W, Chi Y

Therapeutics and Clinical Risk Management 2026, 22:586907

Published Date: 23 April 2026

Original Research

Pregnancy Outcomes Following Medical Therapy versus Levonorgestrel-Releasing Intrauterine System for Atypical Endometrial Hyperplasia

Wang M, Zhao S, Yuan H, Zhao M, Hang C, Yuan R

Therapeutics and Clinical Risk Management 2026, 22:577040

Published Date: 18 April 2026

Original Research

Dynamic Evolution Characteristics and Nursing Intervention Windows of Perioperative Deep Vein Thrombosis in Patients with Lower Extremity Traumatic Fractures: A Prospective Cohort Study

Hu X, Wang Y, Li Y, Cao H, He M, Li Y

Therapeutics and Clinical Risk Management 2026, 22:598379

Published Date: 17 April 2026

Review

Comparison of Percutaneous Coronary Intervention Outcomes for in-Stent vs de Novo Chronic Total Occlusions: A Meta-Analysis

Mao Q, Xie L, Wu J

Therapeutics and Clinical Risk Management 2026, 22:576328

Published Date: 15 April 2026

Original Research

qCON and qNOX-Guided Sedation Monitoring During Gastrointestinal Endoscopy: A Prospective Observational Preliminary Study

Liu Q, Wei D, Han X, Cheng W, Yang X, Min S

Therapeutics and Clinical Risk Management 2026, 22:593667

Published Date: 15 April 2026

Original Research

Efficacy and Safety of Anthracyclines Combined with Temozolomide Regimens for the Treatment of Advanced Leiomyosarcoma: A Retrospective Study

Tan H, Zhou J, Shi S, Jiang L, Zuo L, Su A, Wang H, Sun Y, Xuan W, Chi Y

Therapeutics and Clinical Risk Management 2026, 22:564176

Published Date: 15 April 2026

Original Research

Effect of Dexmedetomidine Combined with Esketamine on Postoperative Fatigue in Patients Undergoing Total Laparoscopic Hysterectomy: A Single-Center Randomized Double-Blinded Controlled Trial

Wu L, Wang Y, Chai Y, Qiu Z, Yin J, Zhang B, Wang G

Therapeutics and Clinical Risk Management 2026, 22:575704

Published Date: 14 April 2026

Review

Artificial Intelligence in the Diagnosis and Management of Pulmonary Tuberculosis: A Review of Current Applications and Future Perspectives

Ou Y, Zhang Q, Meng C, Zhou X, Na M, Yu Z, Ma W, Huang C

Therapeutics and Clinical Risk Management 2026, 22:596651

Published Date: 31 March 2026

Original Research

Real-World Evidence on Statin Use for Traumatic Brain Injury Associated Degenerative Neurological Disorders

Lin YH, Tsai IJ, Chang YA, Huang CH, Chang CC

Therapeutics and Clinical Risk Management 2026, 22:591742

Published Date: 26 March 2026

Original Research

Preoperative Portal Vein Thrombosis Grading Predicts Post-Transplant Thrombosis and Survival

Liu Y, Tian JS, Wang YN, Wang ZR, Cao J, Shi ZY

Therapeutics and Clinical Risk Management 2026, 22:565328

Published Date: 25 March 2026

Review

From Tradition to Future: Pathophysiological Mechanisms and Clinical Research Progress in the Treatment of Hypothyroidism with Traditional Chinese Medicine——A Narrative Review

Piao L, Ma J, Zhao N, Liu C, Hou Y, Wang T

Therapeutics and Clinical Risk Management 2026, 22:581042

Published Date: 21 March 2026

Review

The Therapeutic Role of Biologics in Chronic Rhinosinusitis with Nasal Polyps (CRSwNP): A Review of the Current Evidence

Chen W, Wen Y, Wang J, Meng X, Su L, Wu Y

Therapeutics and Clinical Risk Management 2026, 22:586959

Published Date: 17 March 2026

Original Research

Efficacy of an Intelligent Closed-Loop Warming System in Preventing Perioperative Hypothermia and Improving Recovery in Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial

Chen R, Du Y, He X, Fan J, Zhang Y, Bai Y, Liu M, Shen W, Yu T, Wang G

Therapeutics and Clinical Risk Management 2026, 22:579479

Published Date: 13 March 2026

Original Research

Therapeutic Efficacy of Full-Endoscopic Unilateral Laminotomy with Bilateral Decompression for Degenerative Cervical Myelopathy: A Retrospective Cohort Study

Gong W, Tang S, Wu W, Lu H, Ma X

Therapeutics and Clinical Risk Management 2026, 22:583348

Published Date: 6 March 2026

Review

A Narrative Review of Remnant Cholesterol as an Independent Atherogenic Lipoprotein in Type 2 Diabetes: Pathophysiology and Clinical Implications

Natsir RM, Halimah E, Diantini A, Levita J

Therapeutics and Clinical Risk Management 2026, 22:593168

Published Date: 3 March 2026

Original Research

Association Between Serum Vitamin D Levels and Metformin Efficacy in Obese Type 2 Diabetes Patients: A Retrospective Cohort Study Based on HbA1c Reduction

Wang Y, Liu H, Li Y, Wnag X, He C, Wei Z

Therapeutics and Clinical Risk Management 2026, 22:565034

Published Date: 13 February 2026

Original Research

Effects of ICS + LABA Combination Therapy on Asthma Control: An Observational Study in Real-World Settings

Han P, Wang L

Therapeutics and Clinical Risk Management 2026, 22:547261

Published Date: 7 February 2026

Review

Exploring the Comprehensive Treatment of Hashimoto’s Thyroiditis with Traditional Chinese Medicine from the Perspective of Modern Medicine

Zhang J, Huang G

Therapeutics and Clinical Risk Management 2026, 22:575059

Published Date: 6 February 2026

Original Research

ECG-Guided Antiarrhythmic Therapy in Acute Coronary Syndrome: A Multidimensional Assessment of Biomarkers, Cardiac Function, and Quality of Life

Li X, Liu X, Jing M, Yang C, Luo H, Li L

Therapeutics and Clinical Risk Management 2026, 22:583212

Published Date: 6 February 2026

Original Research

Clinical and Procedural Predictive Model for Pneumothorax Risk After CT-Guided Lung Biopsy

Qin Y, Zhao Z, Zhang L, Shao X, Wang Q

Therapeutics and Clinical Risk Management 2026, 22:579698

Published Date: 5 February 2026

Original Research

Clinical Efficacy of Levocarnitine-Alprostadil Combination Therapy on Indicators of Renal Function, Oxidant-Antioxidant Balance, and Systemic Inflammation in Patients with End-Stage Diabetic Nephropathy

Cheng L, Wan S, Min Y, Tu C, Mao D, Wang Q, Fu S, Xiong F

Therapeutics and Clinical Risk Management 2026, 22:553649

Published Date: 3 February 2026

Clinical Trial Report

Impact of Individualized Positive End-Expiratory Pressure Guided by Driving Pressure on Postoperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic Surgery Patients: A Randomized Controlled Trial

Zhang Y, Zhu J, Xi C, Su S, Bai Y, Zhang Y, Shen W, Wang G

Therapeutics and Clinical Risk Management 2026, 22:564979

Published Date: 31 January 2026

Original Research

Aspartate Aminotransferase-to-Platelet Ratio Index (APRI) as a Predictor of Mortality in Patients with Femoral Fracture: A Retrospective Cohort Analysis

Kuo PJ, Wu SC, Hsu SY, Hsieh CH

Therapeutics and Clinical Risk Management 2026, 22:553629

Published Date: 22 January 2026

Original Research

Ten-Year Outcomes of Modular Reverse Shoulder Arthroplasty Assessed by 3D Motion Analysis

Hetto P, Liewald F, Maier MW, Tsitlakidis S, Spranz D

Therapeutics and Clinical Risk Management 2026, 22:546875

Published Date: 20 January 2026

Original Research

Risk Factors for Ileus After Radical Gastrectomy for Gastric Cancer and Construction of a Nomogram Prediction Model

Niu M, Qiao Y, Wang B, Zhang J

Therapeutics and Clinical Risk Management 2026, 22:553770

Published Date: 19 January 2026

Original Research

Clinical Outcomes of Percutaneous Mitral Valve Repair with Mitraclip®: A Longitudinal Observational Study (The Mitra-Angio-CDO Study)

Melo-Burbano LÁ, Bonilla-Bonilla DM, Daza-Arana JE, Lozada-Ramos H, Dager AE, Fonseca JA

Therapeutics and Clinical Risk Management 2026, 22:549225

Published Date: 17 January 2026

Original Research

Prospective Evaluation of Postoperative SIRS and Serum Inflammatory Indices in Percutaneous Nephrolithotomy Patients

Arslantas YB, Sonmez G, Baydilli N, Bas U, Tosun H, Demirci D, Akinsal EC

Therapeutics and Clinical Risk Management 2026, 22:568497

Published Date: 15 January 2026

Original Research

Impact of the Charlson Comorbidity Index on the Short-Term and Long-Term Prognoses of Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention

Ma Y, Luo H, Zhao H, Zhao O, Ma L, Yang W, Yi M, Sun L, Li J

Therapeutics and Clinical Risk Management 2026, 22:559412

Published Date: 14 January 2026

Original Research

Real-World Clinical Effectiveness and Migraine-Related Healthcare Resource Utilization in Patients Initiating Fremanezumab in Germany and the United Kingdom

Heinze A, Afridi SK, Totev TI, Krasenbaum LJ, Terasawa E, Akcicek H, Hipp J, Dhiraj D, Sun R, Yim E, Yilma B, Driessen MT

Therapeutics and Clinical Risk Management 2026, 22:529550

Published Date: 14 January 2026