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Papers published by Professor Guang Liang:
Inhibition of JNK Phosphorylation by Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury [Corrigendum]
Xiao Z, Xu F, Zhu X, Bai B, Guo L, Liang G, Shan X, Zhang Y, Zhao Y, Zhang B
Drug Design, Development and Therapy 2022, 16:249-250
Published Date: 19 January 2022
An Indole-2-Carboxamide Derivative, LG4, Alleviates Diabetic Kidney Disease Through Inhibiting MAPK-Mediated Inflammatory Responses
Qian J, Yin S, Ye L, Wang Z, Shu S, Mou Z, Xu M, Chattipakorn N, Liu Z, Liang G
Journal of Inflammation Research 2021, 14:1633-1645
Published Date: 27 April 2021
Allylated Curcumin Analog CA6 Inhibits TrxR1 and Leads to ROS-Dependent Apoptotic Cell Death in Gastric Cancer Through Akt-FoxO3a
Rajamanickam V, Yan T, Wu L, Zhao Y, Xu X, Zhu H, Chen X, Wang M, Liu Z, Liu Z, Liang G, Wang Y
Cancer Management and Research 2020, 12:247-263
Published Date: 13 January 2020
L61H46 Shows Potent Efficacy Against Human Pancreatic Cancer Through Inhibiting STAT3 Pathway [Erratum]
Bai E, Yang L, Xiang Y, Hu W, Li C, Lin J, Dai X, Liang G, Jin R, Zhao C
Cancer Management and Research 2019, 11:10683-10684
Published Date: 23 December 2019
Inhibition Of JNK Phosphorylation By Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury
Xiao Z, Xu F, Zhu X, Bai B, Guo L, Liang G, Shan X, Zhang Y, Zhao Y, Zhang B
Drug Design, Development and Therapy 2019, 13:4161-4171
Published Date: 10 December 2019
Indole-2-Carboxamide Derivative LG25 Inhibits Triple-Negative Breast Cancer Growth By Suppressing Akt/mTOR/NF-κB Signalling Pathway
Xu X, Rajamanickam V, Shu S, Liu Z, Yan T, He J, Liu Z, Guo G, Liang G, Wang Y
Drug Design, Development and Therapy 2019, 13:3539-3550
Published Date: 11 October 2019
Acid-responsive nanoparticles as a novel oxidative stress-inducing anticancer therapeutic agent for colon cancer
Zhao C, Cao W, Zheng H, Xiao Z, Hu J, Yang L, Chen M, Liang G, Zheng S, Zhao C
International Journal of Nanomedicine 2019, 14:1597-1618
Published Date: 28 February 2019
Rhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway
Yang L, Li J, Xu L, Lin S, Xiang Y, Dai X, Liang G, Huang XY, Zhu J, Zhao C
Cancer Management and Research 2019, 11:1167-1176
Published Date: 1 February 2019
A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction
Dai X, Zhang J, Guo G, Cai Y, Cui R, Yin C, Liu W, Vinothkumar R, Zhang T, Liang G, Zhang X
Cancer Management and Research 2018, 10:3069-3082
Published Date: 29 August 2018
Design, synthesis, and structure–activity relationships of 2-benzylidene-1-indanone derivatives as anti-inflammatory agents for treatment of acute lung injury
Xiao S, Zhang W, Chen H, Fang B, Qiu Y, Chen X, Chen L, Shu S, Zhang Y, Zhao Y, Liu Z, Liang G
Drug Design, Development and Therapy 2018, 12:887-899
Published Date: 19 April 2018
L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway
Bai E, Yang L, Xiang Y, Hu W, Li C, Lin J, Dai X, Liang G, Jin R, Zhao C
Cancer Management and Research 2018, 10:565-581
Published Date: 23 March 2018
Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer
Shi L, Zheng H, Hu W, Zhou B, Dai X, Zhang Y, Liu Z, Wu X, Zhao C, Liang G
OncoTargets and Therapy 2017, 10:1767-1776
Published Date: 23 March 2017
Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway
Kang Y, Hu W, Bai E, Zheng H, Liu Z, Wu J, Jin R, Zhao C, Liang G
OncoTargets and Therapy 2016, 9:7373-7384
Published Date: 5 December 2016
A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo
Ge X, Feng Z, Xu T, Wu B, Chen H, Xu F, Fu L, Shan X, Dai Y, Zhang Y, Liang G
Drug Design, Development and Therapy 2016, 10:1947-1959
Published Date: 24 June 2016
Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells
Jin R, Xia Y, Chen Q, Li W, Chen D, Ye H, Zhao C, Du X, Shi D, Wu J, Liang G
Drug Design, Development and Therapy 2016, 10:979-995
Published Date: 2 March 2016
Determination of the binding mode for anti-inflammatory natural product xanthohumol with myeloid differentiation protein 2
Fu W, Chen L, Wang Z, Zhao C, Chen G, Liu X, Dai Y, Cai Y, Li C, Zhou J, Liang G
Drug Design, Development and Therapy 2016, 10:455-463
Published Date: 27 January 2016
n-Butanol extract from Folium isatidis inhibits lipopolysaccharide-induced inflammatory cytokine production in macrophages and protects mice against lipopolysaccharide-induced endotoxic shock
Jiang LL, Lu YL, Jin JH, Dong LL, Xu FL, Chen SS, Wang ZY, Liang G, Shan XO
Drug Design, Development and Therapy 2015, 9:5601-5609
Published Date: 12 October 2015
Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model
Zhao C, Zhang Y, Zou P, Wang J, He W, Shi D, Li H, Liang G, Yang S
Drug Design, Development and Therapy 2015, 9:1663-1678
Published Date: 18 March 2015
Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin
Zhang Y, Jiang X, Peng K, Chen C, Fu L, Wang Z, Feng J, Liu Z, Zhang H, Liang G, Pan Z
Drug Design, Development and Therapy 2014, 8:2161-2171
Published Date: 4 November 2014
Synthesis and biological evaluation of novel indole-2-one and 7-aza-2-oxindole derivatives as anti-inflammatory agents
Chen G, Jiang L, Dong L, Wang Z, Xu F, Ding T, Fu L, Fang Q, Liu Z, Shan X, Liang G
Drug Design, Development and Therapy 2014, 8:1869-1892
Published Date: 13 October 2014
Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents
Zhang Y, Zhao C, He W, Wang Z, Fang Q, Xiao B, Liu Z, Liang G, Yang S
Drug Design, Development and Therapy 2014, 8:373-382
Published Date: 4 April 2014