Diabetes, Metabolic Syndrome and Obesity
Diabetes Pathophysiology and Complications
Section Editor(s): Dr Conway, Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USAThe pathophysiology and complications of diabetes section welcomes experimental, clinical, and translational research related to the onset and progression of diabetes or its complications. This may be laboratory, animal or human original research studies, meta-analyses, mini-reviews, or reviews. The complications include, but are not limited to, diabetic retinopathy, nephropathy, neuropathy cardiovascular disease, and peripheral vascular disease.
Latest articles in Diabetes Pathophysiology and Complications:
- 25 records -
Association Between the Systemic Inflammatory Response Index and Severe Infection in Patients with Diabetic Foot
Wu P, Xu W, Chen R, Xu Z
Diabetes, Metabolic Syndrome and Obesity 2026, 19:605794
Published Date: 29 June 2026
Obesity-Related Insulin Resistance Indices and CKD Risk in Patients with Diabetes and Coronary Heart Disease: A Multicenter Cohort Analysis
Zhang J, Zhang Z, He Y, Liu S, Zhao J, Ge X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:610602
Published Date: 26 June 2026
Targeting Mitochondria-Associated Endoplasmic Reticulum Membranes (MAMs): A Novel Therapeutic Strategy for Diabetic Complications
Shi J, Sun X, You J, Ji X, Xie J, Li Y, Gu K, Wei X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:599670
Published Date: 25 June 2026
Integrated Bioinformatic and Experimental Identification of DHCR24 and NRG1 as Key Cellular Aging Genes in Diabetic Cardiomyopathy
Xiao WW, Gao X, Zhang XR, Li HY, Zou ALZ, Miao ZM, Zou SP, Chen HJ, Yu SM
Diabetes, Metabolic Syndrome and Obesity 2026, 19:578414
Published Date: 23 June 2026
Beyond Diabetes Classification: Interpreting Vectorcardiographic Repolarization Geometry as a Cardiometabolic Electrical Phenotype [Letter]
Zhu X, Lu Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:626659
Published Date: 17 June 2026
Association of the Triglyceride-Glucose Index and Its Central Obesity Derivatives with Peripheral Artery Disease in Type 2 Diabetes: A Cross-Sectional Study
Guo Y, Zhou X, Chen L, Zheng J
Diabetes, Metabolic Syndrome and Obesity 2026, 19:602358
Published Date: 5 June 2026
MHR and CRP/Albumin Ratio Correlate with Wagner Grade in Diabetic Foot Ulcers: A Chinese Retrospective Study with Pathogen Analysis
Song J, Liu T, Yu Y, Sun K, Zheng L
Diabetes, Metabolic Syndrome and Obesity 2026, 19:605013
Published Date: 4 June 2026
Trimethylamine N-Oxide Combined with Phenylacetylglutamine as Potential Biomarkers for Diabetic Kidney Disease
Xiong G, Fang Q, Wu H, Zhang D, Wang J, Qin Y, Chen Z, Wu Y, Lei Y, Cui Y, Chen L, Li X, Li Y, Ouyang D
Diabetes, Metabolic Syndrome and Obesity 2026, 19:592052
Published Date: 29 May 2026
Lactate Metabolism and Protein Lactylation in Diabetic Kidney Disease: A Narrative Review
Sun L, Yang Y, Pan W, Zhang C, Lu J, Guo S, Zhu Y, Zhu M
Diabetes, Metabolic Syndrome and Obesity 2026, 19:599060
Published Date: 29 May 2026
Biofilm–Host Immune Crosstalk at the Diabetic Foot Ulcer Interface: Molecular Mechanisms, Immune Evasion, and Next-Generation Anti-Biofilm Strategies
Han Y, Yang Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:608789
Published Date: 22 May 2026
Modulating the Gut-Nerve Axis and Inflammation: A Narrative Review of Dietary Patterns in Diabetic Peripheral Neuropathy
Sun R, Li X, Liu X, Guo D, Chen Y, Zhao Y, Yin Y, Zhai X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:602342
Published Date: 21 May 2026
1,5-Anhydroglucitol: From Short-Term Glycemic Monitoring to Risk Stratification of Diabetes Complications
Xu H, Tang Q, Chen Q
Diabetes, Metabolic Syndrome and Obesity 2026, 19:596620
Published Date: 14 May 2026
Diabetes-Related Alterations in Vectorcardiographic Repolarization Geometry: Insights from Physiological and Machine-Learning Analysis
Lv Q, Zhao H
Diabetes, Metabolic Syndrome and Obesity 2026, 19:586572
Published Date: 13 May 2026
SLC30A8 Promoter Hypomethylation is Associated with Impaired Renal Function in Type 2 Diabetes: A Cross-Sectional Study
Guo C, Yang W, Xue R, Zhou Q, Liang Y, Zhang XL
Diabetes, Metabolic Syndrome and Obesity 2026, 19:600905
Published Date: 12 May 2026
Development and Validation of a Nursing-Integrated Nomogram to Predict 1-Year Ulcer Recurrence in Patients with Diabetic Foot Ulcers After Endovascular Therapy
Fu L, Zeng W, Ding H, Chen Z, Chen X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:591186
Published Date: 23 April 2026
The Central Role of Lipid Metabolism Disorders in Diabetes Mellitus: Mechanisms, Clinical Manifestations, and Emerging Therapeutic Strategies
Yang Q, Liu X, Zhang T, Zhao X, Xiao X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:591764
Published Date: 16 April 2026
Skin Organoids in Diabetic Chronic Wounds: Current Status and Future Perspectives
Wang Z, Hou M, Pei J, Gao F, Li Z
Diabetes, Metabolic Syndrome and Obesity 2026, 19:598026
Published Date: 16 April 2026
Early Pregnancy Triglyceride to HDL-C Ratio Predicts Gestational Diabetes Mellitus and Neonatal Hypoglycemia: A Retrospective Cohort Study
Jiang L, Shao H, Wang X, Wu J, Dong F
Diabetes, Metabolic Syndrome and Obesity 2026, 19:590161
Published Date: 11 April 2026
Clinical Significance of Serum CCR2 and IDO1 in Diabetic Peripheral Neuropathy
Liu Y, Yang Q
Diabetes, Metabolic Syndrome and Obesity 2026, 19:579354
Published Date: 25 March 2026
Construction of a Risk Prediction Model and Associative Path Analysis for Impaired Awareness of Hypoglycemia in People with Diabetes
Wen X, Chen L, Mo Y, Guo H, Pei R, Lyu Y, Luo H, Wang J
Diabetes, Metabolic Syndrome and Obesity 2026, 19:579326
Published Date: 25 March 2026
Clinical Characteristics and Development of a Risk-Identification Model for Incidentally Detected Cancer in Patients with Diabetes: A Case–Control Study
Cheang N, Chen X, Zhang H, Su Q, Du S
Diabetes, Metabolic Syndrome and Obesity 2026, 19:581946
Published Date: 24 March 2026
Metabolic Crosstalk in Diabetic Kidney Disease: Synergistic Effects of Glucotoxicity and Lipotoxicity
Cao J, Dun Z, Tian D, Qiao Z, Wang Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:580866
Published Date: 23 March 2026
Thyroid Hormone Indices and Histopathological Severity of Diabetic Nephropathy in Euthyroid Patients with Type 2 Diabetes: A Biopsy-Based Cross-Sectional Study
Wang X, Zhang C, Zhao X, Zhao S, Zhang F, Li C, Hao Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:589576
Published Date: 23 March 2026
Quality of Clinical Practice Guidelines for Diabetic Foot Management: A Systematic Review Using the AGREE II and AGREE-REX Instruments
Song Y, Cui ZF, Wu ZQ, Liu XB, Li WQ, Zhu C, Que T, Zhao SS, Wang XL, Yang GX, Liu WJ
Diabetes, Metabolic Syndrome and Obesity 2026, 19:586150
Published Date: 23 March 2026
A Novel Nomogram for Diabetic Retinopathy Prediction in Young and Middle-Aged Patients with Type 2 Diabetes
Ma L, Shi S, Wang J, Shi S, Zhang Y, Wang X, Shi S, Huang K, Zhang Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:582107
Published Date: 12 March 2026