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Diabetes, Metabolic Syndrome and Obesity

ISSN: 1178-7007

Professor Gian Paolo Fadini

Professor Fadini

Department of Medicine, University of Padova, Padova, Italy

Dr. Fadini is full Professor of Endocrinology at the University of Padova and Associate Medical Director at the Division of Metabolic Diseases of the University Hospital of Padova. Dr. Fadini also directs the Laboratory of Experimental Diabetology at the Veneto Institute of Molecular Medicine. 

Dr. Fadini’s teaching activity is directed to students of the M.D. course in Medicine and Surgery and of the Specialty course in Endocrinology and Metabolism.

Dr. Fadini research activities are devoted to the study of diabetic complications, stem cells in diabetes, wound healing, metabolic syndrome and insulin resistance, oxidative stress, longevity gene pathways in metabolic diseases. With a series of clinical translational studies on endothelial progenitor cells, Dr. Fadini research activity has contributed to the understanding of how diabetes induces vascular damage and compromised endothelial repair. He then has moved to consider the bone marrow as a target of diabetic complications, which regulates vascular stem cells and regeneration. In the field of clinical diabetes, Dr. Fadini designed and coordinated studies using routinely accumulated clinical data on cardiovascular outcomes and real-world effectiveness of glucose lowering medications, including the nationwide Italian DARWIN study series.

Dr. Fadini has received prestigious international prizes, including the Morgagni Silver Medal and the EASD (European Association for the Study of Diabetes) Minkowski prize.

Dr. Fadini has been Associate Editor for Atherosclerosis, Journal of Endocrinological Investigation and Nutrition Metabolism & Cardiovascular Disease, and is current board member of European Heart Journal, Cardiovascular Diabetology, and Diabetes Obesity & Metabolism.

Dr. Fadini has published more than 330 articles in peer-review journals, with H-index of 58.

Prof. Dr. Muthuswamy Balasubramanyam

Prof. Dr. Balasubramanyam

Department of Cell and Molecular Biology, Madras Diabetes Research Foundation, Chennai, India

Dr. Balasubramanyam has recently been elected as Fellow of the National Academy of Medical Sciences (India) and is at present Dean of Research Studies & Senior Scientist at the Madras Diabetes Research Foundation, Chennai, India. He obtained his PhD degree in 1987 from Sri Venkateswara University, Tirupati. During 1991 to 1995, he worked as a Post-Doctoral Scientist at the Hypertension Research Center of the University of Medicine and Dentistry of New Jersey (UMDNJ), Newark, USA on “Cell signaling & Molecular medicine aspects with special reference to diabetes’. During 1996-99, he served as a faculty at the Center for Biotechnology, Anna University, Chennai. He joined the Madras Diabetes Research Foundation in 1999 and instrumental in many of its academic developments including infrastructure for basic science and translational studies. He has over 115 original research publications and many awards to his credit.

Dr. Balasubramanyam’s specialization and research interests include: Disease-Biology and molecular medicine with special reference to diabetes and its vascular complications, metabolic syndrome & obesity, molecular mechanisms of accelerated ageing, redox signaling and ‘biomarkers’ of oxidative stress, role of microinflammation, ER stress, telomere biology, the gut (microbiota) connection to diabetes, proteomics/epigenetics/miRNA profiling in fat and skeletal muscle with special reference to insulin signaling and drug discovery, metabolomics, exposomics, stem cell research, role of endocrine disruptors, bio-prospecting molecular targets of herbal action and development of cell-based, high-throughput assays as well as point-of-care (POC) medical devices.

Dr. Balasubramanyam is also an elected Member of the Asia-Pacific International Molecular Biology Network (A-IMBN). He has recently received the prestigious Endeavour Executive Fellowship from the Education Department of Govt. of Australia. He serves as an Expert Committee member in many funding agencies of Govt. of India. At national and international levels, he serves as an expert member of multiple grant review panels and on the editorial advisory boards of multi-disciplinary journals.

Prof. Dr. Antonio Brunetti

Prof. Dr. Brunetti

Department of Health Sciences, University “Magna Græcia” of Catanzaro, Catanzaro, Italy

Dr. Antonio Brunetti is a Professor in Endocrinology at the University “Magna Græcia” of Catanzaro, Italy. He graduated in medicine and specialized in Endocrinology and Metabolism at the University of Catania, Italy. In 1992 he obtained the PhD degree in Endocrine and Metabolic Sciences from the University of Naples, Italy, while he was working at the Division of Diabetes & Endocrine Research, University of California San Francisco (UCSF), USA. During his PhD programme at UCSF, Prof. Brunetti led and was the principal investigator of a series of studies that helped to clarify most of the molecular mechanisms involved in insulin action and the regulation of insulin receptor gene expression in muscle, liver and fat.

Over the past 15 years his research activity has mostly focused on the molecular genetics of insulin resistance and type 2 diabetes, followed by the discovery of a novel mechanism for insulin resistance in a subset of diabetic patients. These studies have helped to identify critical components of the transcriptional machinery that governs insulin receptor gene expression, indicating that defects in the architectural factor HMGA1 (the most important among these components) may cause “HMGA1opathy”, a novel insulin resistance subphenotype observed in patients with either rare forms of insulin resistance or common type 2 diabetes. The results obtained from these studies have provided insights into previously unexplored aspects of insulin resistance and have been presented in various international conferences and published in leading peer reviewed journals.

His current research includes the study of chronic inflammation and hypoxia in fat and their role in the development of obesity-related insulin resistance in the effort to identify new biological targets and biomarkers of early disease. The actual researching activity is also centered on the study of gestational diabetes mellitus (GDM) and the identification of early predictors of GDM and glucose intolerance during pregnancy.

From 2008 to 2016 he coordinated the PhD programme in Endocrine-Metabolic and Nutritional Sciences at the University “Magna Græcia” of Catanzaro. Currently he is a member of the PhD programme in Biomarkers of chronic and complex diseases, and Director of the Operative Unit of Endocrinology and Metabolism at the Azienda Ospedaliero-Universitaria “Mater Domini”, University “Magna Græcia” of Catanzaro, Italy. At national and international levels, he has served as member of multiple editorial boards, and is an active member of various professional societies.

Prof. Dr. Juei-Tang Cheng

Prof. Dr. Cheng

Institute of Medical Research, Chang Jung Christian University, Tainan, Taiwan

Dr. Cheng is a chair-professor at the Chang Jung Christian University and he also serves as a Senior Investigator in Chi-Mei Medical Center. During his PhD thesis research in pharmacology at Shizuoka Pharmaceutical College in Japan, he demonstrated that calcium-induced calcium release in smooth muscle. Then, he was invited as an associate professor at Tajen Pharmaceutical College in Taiwan. He found a nature fruit Guava in the alleviation of diabetic disorders. In 1986, he moved to the National Cheng Kung University to serve as an associate professor in pharmacology. He continued his favorite target, effects of natural products on diabetic complications. Depending on several findings, he promoted to the professor in the same university. Therefore, Dr. Cheng directed graduate students to investigate the pathophysiology of diabetes and the role of peptides in neuroendocrinology. He characterized the mediation neuropeptide Y in diabetic disorders and established the major role of beta-endorphin in metabolic regulation. In 1996, Dr. Cheng became the chairman of the Research Center for Traditional Chinese Medicine in his university. He used herbal products to demonstrate several findings in the alleviation of diabetic disorders. Therefore, Dr. Cheng got the Fellowship (FCP) from the American College of Clinical Pharmacology. He developed the role of opioid mu-receptors in the metabolic regulation and suggested endogenous receptors are helpful in the regulation of metabolism. Additionally, mediation of endogenous imidazoline receptors in diabetes has also been demonstrated in several publications. Since 2009, Dr. Cheng was retired and moved to the present university. His current research includes a systems biology approach to study the processes of metabolic disorders in efforts to identify new targets for the handling of diabetes and/or metabolic syndrome.

Dr. Cheng has been an active member of the American Diabetes Association (ADA) and New York Academy of Sciences, where he has been involved in the development of basic research to assist handling of metabolic disorders.  At national and international levels, he has served as a member of grant review panels and on the editorial advisory boards of multiple journals.


Dr Konstantinos Tziomalos

Dr Tziomalos

Department of Internal Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece

Konstantinos Tziomalos is Assistant Professor of Internal Medicine at the First Propedeutic Department of Internal Medicine of the Medical School, Aristotle University of Thessaloniki, in AHEPA Hospital, Thessaloniki, Greece. He completed his residency at the Second Propedeutic Department of Internal Medicine of the Medical School, Aristotle University of Thessaloniki, in Hippokration Hospital, Thessaloniki, Greece. He then served as a clinical research fellow at the Department of Clinical Biochemistry (Vascular Prevention Clinic), Royal Free Campus, University College London Medical School, University College London, UK and as a post-doctorate research fellow at the Stem Cell Institute and Cardiovascular Research Laboratory, Division of Cardiology, Miller School of Medicine, University of Miami, USA.

His research interests include dyslipidemia, stroke and cardiovascular disease prevention. He has authored more than 300 peer-reviewed scientific articles, which have received more than 6000 citations.

Editorial Board

Intekhab Ahmed, Division of Endocrinology, Diabetes and Metabolic Diseases, Department of Medicine, Jefferson Medical College, PA, USA

Ammar Mohammed Hamood AL-Farga, Department of Biochemistry, Faculty of Science University of Jeddah, Saudi Arabia

Eman Alissa, Clinical Biochemistry Department, Faculty of Medicine, King Abdulaziz University, Saudi Arabia

Professor Julien S Baker Ph.D, D.Sc, FPhysiol, FRSoBiol, FHBiolAssoc, FITEI, FInClinR, C.Biol, C.Sci., Faculty of Social Sciences, Director, Centre for Health and Exercise Science Research, Head, Department of Sport, and Physical Education, Hong Kong Baptist University, Kowloon Tong, Hong Kong.

Abdulbari Bener, Advisor to WHO, Professor of Public Health, Dept. of Biostatistics & Medical Informatics, Schools of Medicine, Dentistry and Pharmacy, Istanbul Medipol University, Turkey

Baptist Gallwitz, Professor, Deputy Director, Medical Clinic IV, University Hospital Tübingen, Tübingen, Germany

Hassan Hosseinzadeh, Dr, Associate Professor, School of Health & Society, University of Wollongong NSW Australia. 

Claes-Göran Östenson, Professor of Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Amer Rajab, Department of Surgery, Ohio State University Medical Center, Columbus, Ohio, USA

Amy Jo Riggs, Health and Kinesiology Department, Georgia Southern University, GA, USA

Kerry Stewart, Professor of Medicine, Director, Clinical and Research Exercise Physiology, John Hopkins University School of Medicine, MD, USA.

Professor Jing Sun is Professor of Biostatistics at the School of Medicine and Dentistry, Griffith University, Australia.

Wen-Zhu Yang, Lethbridge Research Centre, Agriculture and Agri-Food Canada, Canada

Allan Z. Zhao, Ph.D., Member, the National 1000 Talents Program; Distinguished Professor, The Institute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, People's Republic of China