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• Methylnaltrexone for Opioid-Induced Constipation (1)
• Tapentadol for moderate to severe acute pain in children and adolescents (10)
• Inhaled methoxyflurane for the treatment of acute trauma pain (4)
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• Tapentadol: just another opioid or an innovative strong analgesic? (8)
• From acute to chronic pain: bench to bedside findings from consortium of SIMPAR young researchers (4)
• Oral Methylnaltrexone in the treatment of patients with opioid-induced constipation and noncancer pain (2)
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Editorial

Pediatric Pain

Analgesic Drug Development for Children: A History of Shortcomings … Until Now

Dinh A, Berger A, Krane E

Journal of Pain Research 2021, 14:867-870

Published Date: 31 March 2021

Original Research

Tapentadol for the Treatment of Moderate-to-Severe Acute Pain in Children Under the Age of Two Years

Eissa A, Tarau E, Beuter C, Radic T, Watson E, Sohns M, Lefeber C, Hammer GB

Journal of Pain Research 2021, 14:229-248

Published Date: 29 January 2021

Review

Outcomes of the Pediatric Development Plan of Tapentadol

Eerdekens M, Radic T, Sohns M, Khalil F, Bulawa B, Elling C

Journal of Pain Research 2021, 14:249-261

Published Date: 29 January 2021

Perspectives

The challenge of developing pain medications for children: therapeutic needs and future perspectives

Eerdekens M, Beuter C, Lefeber C, van den Anker J

Journal of Pain Research 2019, 12:1649-1664

Published Date: 23 May 2019

Original Research

Pharmacokinetics, safety, and efficacy of tapentadol oral solution for treating moderate to severe pain in pediatric patients

Muse D, Tarau E, Lefeber C, Sohns M, Brett M, Goldberg J, Rosenburg R

Journal of Pain Research 2019, 12:1777-1790

Published Date: 31 May 2019

Original Research

First evaluation of tapentadol oral solution for the treatment of moderate to severe acute pain in children aged 6 to <18

Finkel JC, Goldberg J, Rosenburg R, Ariyawansa J, Sun T, Ochs-Ross R, Zannikos P, Zhang L, Etropolski M

Journal of Pain Research 2019, 12:1925-1936

Published Date: 28 June 2019

Original Research

Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population

Watson E, Khandelwal A, Freijer J, van den Anker J, Lefeber C, Eerdekens M

Journal of Pain Research 2019, 12:2835-2850

Published Date: 14 October 2019

Original Research

Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to <18 years – a randomized, double-blind, placebo-controlled trial

Beuter C, Volkers G, Radic T, Goldberg J, van den Anker J

Journal of Pain Research 2019, 12:3099-3112

Published Date: 13 November 2019

Original Research

Population Pharmacokinetics of Tapentadol in Children from Birth to <18 Years Old

Khalil F, Choi SL, Watson E, Tzschentke TM, Lefeber C, Eerdekens M, Freijer J

Journal of Pain Research 2020, 13:3107-3123

Published Date: 24 November 2020

Original Research

Tapentadol Prolonged Release for Long-Term Treatment of Pain in Children

Howard RF, Radic T, Sohns M, Eerdekens M, Waßmuth A

Journal of Pain Research 2020, 13:3157-3170

Published Date: 30 November 2020