Back to Journals » Journal of Pain Research » Tapentadol: just another opioid or an innovative strong analgesic?

Journal of Pain Research


Journal Articles:

In recent years, it has emerged that pain signaling and modulatory mechanisms change following physiopathological events, such as neuropathic and inflammatory pain, the two major types of pain. Very different chemical events and ion channel changes, respectively, underlie these types of pain at peripheral levels, so treatments have to differ. Understanding the mechanisms for pain enhancement and modulation can help explain these altered pain states in patients and will lead to more effective treatments. This series describes Tapentadol, the only member of the new MOR-NRI class of analgesic agents, and its potential as a new option for the treatment of cancer and noncancer pain.

Tapentadol: a new option for the treatment of cancer and noncancer pain

Dickenson AH, Kress HG

Journal of Pain Research 2019, 12:1509-1511

Published Date: 16 May 2019

Pharmacological rationale for tapentadol therapy: a review of new evidence

Romualdi P, Grilli M, Canonico PL, Collino M, Dickenson AH

Journal of Pain Research 2019, 12:1513-1520

Published Date: 16 May 2019

Tapentadol: an effective option for the treatment of back pain

Coluzzi F, Polati E, Freo U, Grilli M

Journal of Pain Research 2019, 12:1521-1528

Published Date: 16 May 2019

Tapentadol in the treatment of osteoarthritis: pharmacological rationale and clinical evidence

Rinonapoli G, Coaccioli S, Panella L

Journal of Pain Research 2019, 12:1529-1536

Published Date: 16 May 2019

Tapentadol for neuropathic pain: a review of clinical studies

Freo U, Romualdi P, Kress HG

Journal of Pain Research 2019, 12:1537-1551

Published Date: 16 May 2019

Where should analgesia lead to? Quality of life and functional recovery with tapentadol

Panella L, Rinonapoli G, Coaccioli S

Journal of Pain Research 2019, 12:1561-1567

Published Date: 16 May 2019

Tapentadol: an overview of the safety profile

Polati E, Canonico PL, Schweiger V, Collino M

Journal of Pain Research 2019, 12:1569-1576

Published Date: 16 May 2019