Neuropsychiatric Disease and Treatment

Suicide Prevention and Intervention: Recent Evidence and Future Directions

Suicide is an ongoing global public health concern, with over 800,000 deaths annually worldwide, and an estimated 20-25 times more attempts. The enduring impacts on families and communities cannot be overstated, with recent estimates suggesting over 100 people are affected for each death by suicide. Risk and protective factors are complex, spanning biological factors such as brain connectivity and genetic markers, psychological factors such as hopelessness and psychological pain, and social/environmental factors such as housing insecurity and financial stress. Unfortunately, despite increasing awareness and research interest in recent decades, suicide risk prediction remains imprecise. There is a need for rigorous research on evidence-based interventions and better understanding of risk and protective factors. It is also vital to recognize the higher risk among specific marginalized communities and the need for culturally competent care. This Article Collection collects and shares recent perspectives in suicide research through a multidisciplinary, transdiagnostic lens. From neurobiological studies of suicide risk to qualitative studies exploring relevant social determinants of health, this collection covers broad perspectives on suicide prevention, intervention, and management.