Nature and Science of Sleep

Animal and Mathematical Models in Sleep Science and Sleep Medicine

Animal models are crucial for studying sleep and sleep disorders. They provide insights into the mechanisms of sleep regulation and the underlying causes of various sleep-related conditions, helping in the development of potential treatments. The previously used models include laboratory dogs, cats, rodents, zebrafish, fruit flies, and nematodes etc. These models have previously helped in understanding the mechanisms and in the development of new treatments for insomnia, restless legs syndrome, narcolepsy, and sleep apnea etc. This Article Collection showcases cutting-edge research that bridges experimental animal and human studies with computational approaches in sleep science and sleep medicine.