International Journal of General Medicine

The Microbiome and Metabolome: Emerging Windows into Human Health and Disease

Advances in multiple now foundational technologies, such as high throughput DNA sequencing and ultra-high resolution liquid chromatography and tandem mass spectrometry, have enabled biologists to generate enormous datasets that comprehensively capture the hundreds to thousands of microbes and small molecules present in biological matrices. At the same time, advances in computational technologies and methods have enabled biologists and bioinformaticians to explore these large omics datasets and identify novel associations between resident microbes, molecules, and human health. Studies using these technologies have also revealed how incomplete our understanding of human biology remains