Infection and Drug Resistance

Advances in Osteomyelitis: Pathogenesis, Diagnosis, and Treatment

Osteomyelitis (OM) refers to osseous tissue infection, with or without surrounding soft tissue infection. It is characterized by inflammatory associated bone destruction, with or without new bone formation. Despite great advances in medical techniques, osteomyelitis remains a catastrophic disorder or complication. On the one hand, the pathogenesis of this disorder is still not fully understood. On the other hand, diagnosis of this disorder is sometimes difficult owing to the non-specific symptoms. In addition, treatment is always tricky, with high risks of infection recurrence and limb disability. Therefore, how to lower the incidence of osteomyelitis is as important as the topic of how to increase the cure rate. This Article Collection contains original research articles covering the current concepts and investigations regarding the pathogenesis, diagnosis, and treatment of osteomyelitis.