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Biologics: Targets and Therapy

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ISSN: 1177-5491

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Biosimilars, Biobetters, and Bioparallels

Looking back on almost three decades of biosimilars and despite their difficult start in Europe in 2015, biosimilars are solidly embedded in patient care and have become a mainstay in human therapeutics – at least in high income countries. Being equivalent in efficacy/effectiveness, safety and (mainly) priced lower than the originators they reference, biosimilars enable savings, expanded patient access, and greater patient equity.

Evaluating Biosimilar Development Projects: An Analytical Framework Utilizing Net Present Value

Ranbhor R, Kulkarni P

Biologics: Targets and Therapy 2025, 19:125-135

Published Date: 25 March 2025

Adalimumab Biosimilars Demonstrate Long-Term Durability and Cost-Effectiveness in Paediatric Inflammatory Bowel Disease: A Real-World Two-Centre European Cohort Study

Ancona S, Armstrong K, Longo C, Rabone R, Merrick V, Henderson P, Gandullia P, Wilson DC, Arrigo S, Russell RK

Biologics: Targets and Therapy 2025, 19:265-279

Published Date: 29 April 2025

Efficacy, Safety, and Cost-Effectiveness of the Infliximab Biosimilar GP-1111 in Patients with Inflammatory Bowel Disease Who Underwent a Nonmedical Switch: A Prospective Cohort Study

Pápista M, Resál T, Bacsur P, Kata D, Farkas B, Bálint A, Fábián A, Bor R, Ivány E, Szepes Z, Farkas K, Juhász Z, Buzás N, Molnár T

Biologics: Targets and Therapy 2025, 19:731-743

Published Date: 18 December 2025