Therapeutics and Clinical Risk Management

Asthma

Asthma remains a major cause of ill-health worldwide that presents as a heterogeneous, chronic inflammatory airways disorder characterized by complex and diverse inflammatory processes including goblet cell hyperplasia, airway smooth muscle hypertrophy and sub-epithelial fibrosis that give rise to airway hyperresponsiveness and reversible airflow limitation. This Thematic Series addresses key aspects of the pathogenesis of asthma that informs diagnosis and treatment together with the development of more effective novel therapy for this important and common condition.