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Promotion of Surgical Masks Antimicrobial Activity by Disinfection and Impregnation with Disinfectant Silver Nanoparticles

Authors Valdez-Salas B, Beltran-Partida E, Cheng N, Salvador-Carlos J, Valdez-Salas EA, Curiel-Alvarez M, Ibarra-Wiley R

Received 9 January 2021

Accepted for publication 19 March 2021

Published 7 April 2021 Volume 2021:16 Pages 2689—2702

DOI https://doi.org/10.2147/IJN.S301212

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Prof. Dr. Anderson Oliveira Lobo


Benjamin Valdez-Salas,1,2 Ernesto Beltran-Partida,1,2 Nelson Cheng,3 Jorge Salvador-Carlos,2 Ernesto Alonso Valdez-Salas,1 Mario Curiel-Alvarez,2 Roberto Ibarra-Wiley2

1Laboratorio de Biología Molecular y Cáncer, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 2Laboratorio de Corrosión y Materiales Avanzados, Instituto de Ingeniería, Universidad Autónoma de Baja California, Mexicali, Baja California, Mexico; 3Magna International Pte Ltd, Singapore

Correspondence: Benjamin Valdez-Salas Tel/Fax +526865664154 Ext. 150
Email [email protected]

Background: The COVID-19 pandemic is requesting highly effective protective personnel equipment, mainly for healthcare professionals. However, the current demand has exceeded the supply chain and, consequently, shortage of essential medical materials, such as surgical masks. Due to these alarming limitations, it is crucial to develop effective means of disinfection, reusing, and thereby applying antimicrobial shielding protection to the clinical supplies.
Purpose: Therefore, in this work, we developed a novel, economical, and straightforward approach to promote antimicrobial activity to surgical masks by impregnating silver nanoparticles (AgNPs).
Methods: Our strategy consisted of fabricating a new alcohol disinfectant formulation combining special surfactants and AgNPs, which is demonstrated to be extensively effective against a broad number of microbial surrogates of SARS-CoV-2.
Results: The present nano-formula reported a superior microbial reduction of 99.999% against a wide number of microorganisms. Furthermore, the enveloped H5N1 virus was wholly inactivated after 15 min of disinfection. Far more attractive, the current method for reusing surgical masks did not show outcomes of detrimental amendments, suggesting that the protocol does not alter the filtration effectiveness.
Conclusion: The nano-disinfectant provides a valuable strategy for effective decontamination, reuse, and even antimicrobial promotion to surgical masks for frontline clinical personnel.

Keywords: surgical mask, antimicrobial, SARS-CoV-2, nanobiotechnology, COVID-19, nanoparticles

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