Cancer Management and Research

Establishing New Standards in Neuroendocrine Tumors: Raising the Bar to Set New Benchmarks

Neuroendocrine neoplasms (NENs) are considered rare diseases because of their low incidence and comprise a heterogeneous group of tumors that span from well-differentiated low-grade relatively indolent tumors to poorly-differentiated high-grade aggressive ones. Nevertheless, NENs are highly prevalent in the general population and their incidence has been constantly rising in the last decades. Therapeutic options for these patients are limited, reflecting the poor insight that we yet have about the biology of this group of tumors. This Article Collection highlights recent advances in the context of clinical management and biology understanding for NENs.