Clinical, Cosmetic and Investigational Dermatology

Dove Medical Press is pleased to invite you to submit your research to the upcoming Article Collection: “Hyaluronic acid fillers: superficial injections Vs tridimensional injections, what changes?” organized by Guest Advisors Professor Raffaele Rauso and Professor Nicola Zerbinati in Clinical, Cosmetic and Investigational Dermatology.

Since the beginning of the 21st century, hyaluronic acid (HA) fillers have become a mainstay in aesthetic medicine; these fillers have been quickly appreciated by both physicians and patients due to HA safety and their temporary effect. HA fillers were born as “dermal filler” in order to be injected in the dermal layer to treat fine lines, but over time physicians understood how to inject them tridimensionally, not only into the skin layer but also in superficial and deep facial fat compartments or over the periosteum in order not only to treat lines but to achieve deep facial feature changes.

Although HA is an absorbable substance when injected into the dermal layer due to the action of endogenous hyaluronidase, when injected deeply it has a different pattern of resorption, sometimes lasting also several years. Not all physicians are aware of this and continuing to inject HA fillers every 6 to 8 months causes, over the years, accumulation of the filler into the face, achieving unpleasant results of “puffy face”. Also the use of hyaluronidase, in order to dissolve HA fillers previously injected, has increased during recent years as shown in the recent medical literature.

Nowadays, most aesthetic patients have the stigmata of previous HA injections and a good physician should be aware of it in order to avoid areas where HA is still present, moreover it is mandatory to have a good knowledge of hyaluronidase uses, especially when an unpleasant result is long-lasting and HA needs to be dissolved in order to repeat the treatment in the right way.

The aim of this collection is to provide scientifically based papers that can give readers a guide on how to approach patients previously injected with HA fillers over the years, potential complications in injecting deep areas already injected, and when and how to use hyaluronidase before to repeat a filler treatment.

All manuscripts submitted to this Article Collection will undergo desk assessment and peer-review as part of our standard editorial process. Guest Advisors for this collection will not be involved in peer-reviewing manuscripts unless they are an existing member of the Editorial Board. Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript.

The deadline for submissions is 1 October 2023. 

Please submit your manuscript on our website, quoting the promo code MWJLR to indicate that your submission is for consideration in this Article Collection.

View all papers in this article collection