Other papers submitted by: Dr Harold Minkowitz

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Papers published by Dr Harold Minkowitz:

Clinical Trial Report

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IV Tramadol – A New Treatment Option for Management of Post-Operative Pain in the US: An Open-Label, Single-Arm, Safety Trial Including Various Types of Surgery

Minkowitz H, Leiman D, Lu L, Reines S, Ryan M, Harnett M, Singla N

Journal of Pain Research 2020, 13:1155-1162

Published Date: 22 May 2020

Original Research

Noteworthy comment: Great example of clinical use of a compound demonstrating agonist directed trafficking- reduced recruitment of b-arrestin. This is particularly relevant in the current climate as this study focuses on an opioid agonist that could yield less development of tolerance in the real world and possibly lead to a lower required dose. This is extremely relevant for all of those involved in pain treatment.

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ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The μ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy

Bergese SD, Brzezinski M, Hammer GB, Beard TL, Pan PH, Mace SE, Berkowitz RD, Cochrane K, Wase L, Minkowitz HS, Habib AS

Journal of Pain Research 2019, 12:3113-3126

Published Date: 14 November 2019

Original Research

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A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (µ-GPS) modulator, for the management of moderate to severe acute pain following abdominoplasty

Singla N, Minkowitz HS, Soergel DG, Burt DA, Subach RA, Salamea MY, Fossler MJ, Skobieranda F

Journal of Pain Research 2017, 10:2413-2424

Published Date: 6 October 2017

Original Research

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A feasibility study to investigate the use of a bupivacaine-collagen implant (XaraColl) for postoperative analgesia following laparoscopic surgery

Hemsen L, Cusack SL, Minkowitz HS, Kuss ME

Journal of Pain Research 2013, 6:79-85

Published Date: 1 February 2013

Original Research

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A randomized, multicenter, pilot study comparing the efficacy and safety of a bupivacaine-collagen implant (XaraColl®) with the ON-Q PainBuster® Post-op Pain Relief System following open gynecological surgery

Cusack SL, Minkowitz HS, Kuss M, Jaros M, Hemsen L

Journal of Pain Research 2012, 5:453-461

Published Date: 2 November 2012

Original Research

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Clinical evaluation of XaraColl®, a bupivacaine-collagen implant, for postoperative analgesia in two multicenter, randomized, double-blind, placebo-controlled pilot studies

Cusack SL, Jaros M, Kuss M, Minkowitz HS, Winkle P, Hemsen L

Journal of Pain Research 2012, 5:217-225

Published Date: 27 June 2012