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Papers published by Professor Konstantinos Kostikas:
Derivation and Definitions of Clinical Study Variables for Multiple Long Term Conditions in Patients with Chronic Obstructive Pulmonary Disease: Protocol for a Modified Delphi Methods and Consensus Study on Behalf of the International Cardiovascular and Respiratory Alliance
Joseph T, Bhutani M, Couper A, Pullen R, Nadarajah R, Alves L, Montero-Arias MF, Al-Lehebi R, Berg DD, Hawkins NM, Hurst JR, Jenkins CR, Kaplan A, Kocks JWH, Kostikas K, Lam CSP, Lapperre TS, Rhee CK, Sattar N, Stolz D, Tse G, Winders T, Price D, Gale CP
Pragmatic and Observational Research 2025, 16:243-251
Published Date: 12 December 2025
Managing Small Airways Dysfunction in COPD Patients in Real Life Under Fixed Triple Combination of Beclomethasone/Formoterol/Glycopyrronium: The MASCOT Real World Evidence Study
Gogali A, Kostikas K, Kyriakopoulos C, Potonos D, Porpodis K, Tsiouprou I, Fouka E, Tryfon S, Papadopoulou E, Kipourou M, Katsoulis K
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1651-1663
Published Date: 23 May 2025
Real-Life Effectiveness of Budesonide/Formoterol as Maintenance and Reliever Treatment via the Elpenhaler® Device in Patients with Asthma: The NOTOS Observational Study
Gogali A, Rovina N, Samitas K, Steiropoulos P, Potonos D, Bertoli M, Papanastasiou P, Ginis A, Kostikas K
Journal of Asthma and Allergy 2025, 18:605-618
Published Date: 21 April 2025
A Delphi Consensus Project to Capture Greek Experts’ Opinion on the Position of Triple Therapies in COPD: Why, When and to Whom
Papaioannou AI, Loukides S, Vassilakopoulos T, Tzanakis N, Kostikas K, Hillas G
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:457-471
Published Date: 26 February 2025
A Real-World Study on the Day and Night-Time Symptoms Among Greek COPD Patients Who Recently Initiated Treatment with Dual Bronchodilation: The DANICO Study
Kostikas K, Dimakou K, Gourgoulianis K, Gaga M, Papapetrou D, Tsoukalas G, Chatziapostolou P, Antoniadis A, Meletis G, Evangelopoulou E, Styliara P, Karypidou I, Gogali A, Kalafatakis K, Tzanakis N
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:2027-2041
Published Date: 1 September 2022
CONQUEST: A Quality Improvement Program for Defining and Optimizing Standards of Care for Modifiable High-Risk COPD Patients
Alves L, Pullen R, Hurst JR, Miravitlles M, Carter V, Chen R, Couper A, Dransfield M, Evans A, Hardjojo A, Jones D, Jones R, Kerr M, Kostikas K, Marshall J, Martinez F, Melle MV, Murray R, Muro S, Nordon C, Pollack M, Price C, Sharma A, Singh D, Winders T, Price DB
Patient Related Outcome Measures 2022, 13:53-68
Published Date: 23 February 2022
CONQUEST Quality Standards: For the Collaboration on Quality Improvement Initiative for Achieving Excellence in Standards of COPD Care
Pullen R, Miravitlles M, Sharma A, Singh D, Martinez F, Hurst JR, Alves L, Dransfield M, Chen R, Muro S, Winders T, Blango C, Muellerova H, Trudo F, Dorinsky P, Alacqua M, Morris T, Carter V, Couper A, Jones R, Kostikas K, Murray R, Price DB
International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:2301-2322
Published Date: 12 August 2021
Maximizing Adherence and Gaining New Information For Your Chronic Obstructive Pulmonary Disease (MAGNIFY COPD): Study Protocol for the Pragmatic, Cluster Randomized Trial Evaluating the Impact of Dual Bronchodilator with Add-On Sensor and Electronic Monitoring on Clinical Outcomes
Price D, Jones R, Pfister P, Cao H, Carter V, Kemppinen A, Holzhauer B, Kaplan A, Clark A, Halpin DMG, Pinnock H, Chalmers JD, van Boven JF, Beeh KM, Kostikas K, Roche N, Usmani OA, Mastoridis P
Pragmatic and Observational Research 2021, 12:25-35
Published Date: 24 May 2021
The Perception of Physicians on Gender-Specific Differences in the Diagnosis of COPD: Results from a Questionnaire-Based Survey
Raherison-Semjen C, Mezzi K, Kostikas K, Mackay AJ, Singh D
International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:901-907
Published Date: 1 April 2021
Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database [Corrigendum]
Kostikas K, Price D, Gutzwiller FS, Jones B, Loefroth E, Clemens A, Fogel R, Jones R, Cao H
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:2559-2560
Published Date: 16 October 2020
Early Clinically Important Improvement (ECII) and Exacerbation Outcomes in COPD Patients
Kostikas K, Mackay AJ, Vogelmeier CF, Frent SM, Gupta P, Banerji D, Patalano F, Pfister PJ, Wedzicha JA
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:1831-1838
Published Date: 28 July 2020
Patient-Reported Outcomes (PROs) in COPD Clinical Trials: Trends and Gaps
Afroz N, Gutzwiller FS, Mackay AJ, Naujoks C, Patalano F, Kostikas K
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:1789-1800
Published Date: 23 July 2020
Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database
Kostikas K, Price D, Gutzwiller FS, Jones B, Loefroth E, Clemens A, Fogel R, Jones R, Cao H
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:1729-1738
Published Date: 16 July 2020
Adequacy of Therapy for People with Both COPD and Heart Failure in the UK: Historical Cohort Study
Kostikas K, Rhee CK, Hurst JR, Agostoni P, Cao H, Fogel R, Jones R, Kocks JWH, Mezzi K, Wan Yau Ming S, Ryan R, Price DB
Pragmatic and Observational Research 2020, 11:55-66
Published Date: 2 June 2020
A Real-World Observational Study Examining the Impact of Aclidinium Bromide Therapy on the Quality of Life, Symptoms, and Activity Impairment of Patients with Chronic Obstructive Pulmonary Disease: The Greek ON-AIR Study
Kostikas K, Vassilakopoulos TI, Tzanakis N, Konstantinidis AK, Kosmas EN, Papiris S, Steiropoulos P, Manali ED, Michaelides SA, Daskos G
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:515-526
Published Date: 6 March 2020
Impact of COPD diagnosis timing on clinical and economic outcomes: the ARCTIC observational cohort study
Larsson K, Janson C, Ställberg B, Lisspers K, Olsson P, Kostikas K, Gruenberger JB, Gutzwiller FS, Uhde M, Jorgensen L, Johansson G
International Journal of Chronic Obstructive Pulmonary Disease 2019, 14:995-1008
Published Date: 13 May 2019
Inhaled corticosteroid use by exacerbations and eosinophils: a real-world COPD population
Vestbo J, Vogelmeier CF, Small M, Siddall J, Fogel R, Kostikas K
International Journal of Chronic Obstructive Pulmonary Disease 2019, 14:853-861
Published Date: 16 April 2019
Dual bronchodilation vs triple therapy in the “real-life” COPD DACCORD study
Buhl R, Criée C, Kardos P, Vogelmeier CF, Kostikas K, Lossi NS, Worth H
International Journal of Chronic Obstructive Pulmonary Disease 2018, 13:2557-2568
Published Date: 24 August 2018
Indacaterol/glycopyrronium reduces the risk of clinically important deterioration after direct switch from baseline therapies in patients with moderate COPD: a post hoc analysis of the CRYSTAL study
Greulich T, Kostikas K, Gaga M, Aalamian-Mattheis M, Lossi NS, Patalano F, Nunez X, Pagano VA, Fogel R, Vogelmeier CF, Clemens A
International Journal of Chronic Obstructive Pulmonary Disease 2018, 13:1229-1237
Published Date: 16 April 2018
Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study
Vogelmeier CF, Chapman KR, Miravitlles M, Roche N, Vestbo J, Thach C, Banerji D, Fogel R, Patalano F, Olsson P, Kostikas K, Wedzicha JA
International Journal of Chronic Obstructive Pulmonary Disease 2018, 13:1125-1134
Published Date: 10 April 2018
The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD
Anzueto AR, Vogelmeier CF, Kostikas K, Mezzi K, Fucile S, Bader G, Shen S, Banerji D, Fogel R
International Journal of Chronic Obstructive Pulmonary Disease 2017, 12:1325-1337
Published Date: 4 May 2017
LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD: a systematic review and meta-analysis
Rodrigo GJ, Price D, Anzueto A, Singh D, Altman P, Bader G, Patalano F, Fogel R, Kostikas K
International Journal of Chronic Obstructive Pulmonary Disease 2017, 12:907-922
Published Date: 17 March 2017
Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING)
Marin JM, Beeh KM, Clemens A, Castellani W, Schaper L, Saralaya D, Gunstone A, Casamor R, Kostikas K, Aalamian-Mattheis M
International Journal of Chronic Obstructive Pulmonary Disease 2016, 11:1425-1434
Published Date: 28 June 2016
The asthma–COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease?
Kostikas K, Clemens A, Patalano F
International Journal of Chronic Obstructive Pulmonary Disease 2016, 11:1297-1306
Published Date: 16 June 2016
