Back to Journals » Pragmatic and Observational Research

Pragmatic and Observational Research

ISSN: 1179-7266

Editor-in-Chief: Professor David Price

An international, peer reviewed, open access journal that publishes data from studies designed to reflect more closely medical interventions in real-world clinical practice compared with classical randomized controlled trials (RCTs).

Classical RCTs are designed to maximise internal validity and to establish an unequivocal cause-and-effect relationship between an intervention and an outcome. Classical RCT populations represent only minority groups of real-life patients and are thus limited in their extent. Complementary data from studies designed to reflect more closely the nature of real-world patients and medicines usage are required to inform guidelines and extrapolate research findings across the broad heterogeneous patient populations encountered in everyday clinical practice.

The journal publishes data from prospective and retrospective studies designed to evaluate outcomes associated with real-world clinical practice. Dissemination of this data and the techniques and approaches used to optimise real-world modeling allows outcome validation and improved standards and collaboration in this growing area of research.

This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE).


Latest articles:

- 5 records -

Variation in Demographic and Clinical Characteristics of Patients with COPD Receiving Care in US Primary Care: Data from the Advancing the Patient EXperience (APEX) in COPD Registry

Fox C, Pace W, Brandt E, Carter V, Chang KL, Edwards C, Evans A, Gaona G, Han MK, Kaplan A, Kent R, Kocks JWH, Kruszyk M, Le Lievre Chantal, LiVoti TM, Mahle C, Make B, Ratigan A, Shaikh A, Skolnik N, Stanley B, Yawn BP, Price DB

Pragmatic and Observational Research 2022, 13:17-31

Published Date: 29 April 2022

Deriving a Standardised Recommended Respiratory Disease Codelist Repository for Future Research

MacRae C, Whittaker H, Mukherjee M, Daines L, Morgan A, Iwundu C, Alsallakh M, Vasileiou E, O’Rourke E, Williams AT, Stone PW, Sheikh A, Quint JK

Pragmatic and Observational Research 2022, 13:1-8

Published Date: 16 February 2022

Perceptions and Experiences of COVID-19 Vaccine Side-Effects Among Healthcare Workers in Southern Ethiopia: A Cross-Sectional Study

Zewude B, Habtegiorgis T, Hizkeal A, Dela T, Siraw G

Pragmatic and Observational Research 2021, 12:131-145

Published Date: 16 December 2021


Read more articles