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Pragmatic and Observational Research


ISSN: 1179-7266

Editor-in-Chief: Professor David Price

An international, peer reviewed, open access journal that publishes data from studies designed to reflect more closely medical interventions in real-world clinical practice compared with classical randomized controlled trials (RCTs).

Classical RCTs are designed to maximise internal validity and to establish an unequivocal cause-and-effect relationship between an intervention and an outcome. Classical RCT populations represent only minority groups of real-life patients and are thus limited in their extent. Complementary data from studies designed to reflect more closely the nature of real-world patients and medicines usage are required to inform guidelines and extrapolate research findings across the broad heterogeneous patient populations encountered in everyday clinical practice.

The journal publishes data from prospective and retrospective studies designed to evaluate outcomes associated with real-world clinical practice. Dissemination of this data and the techniques and approaches used to optimise real-world modeling allows outcome validation and improved standards and collaboration in this growing area of research.

This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE).

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Latest articles:

- 5 records -

Acceptability of Vaccination Against COVID-19 Among Healthcare Workers in the Democratic Republic of the Congo

Kabamba Nzaji M, Kabamba Ngombe L, Ngoie Mwamba G, Banza Ndala DB, Mbidi Miema J, Luhata Lungoyo C, Lora Mwimba B, Cikomola Mwana Bene A, Mukamba Musenga E

Pragmatic and Observational Research 2020, 11:103-109

Published Date: 29 October 2020

Patients with Sore Throat: A Survey of Self-Management and Healthcare-Seeking Behavior in 13 Countries Worldwide

van der Velden AW, Sessa A, Altiner A, Pignatari ACC, Shephard A

Pragmatic and Observational Research 2020, 11:91-102

Published Date: 10 September 2020

The CHRONICLE Study of US Adults with Subspecialist-Treated Severe Asthma: Objectives, Design, and Initial Results

Ambrose CS, Chipps BE, Moore WC, Soong W, Trevor J, Ledford DK, Carr WW, Lugogo N, Trudo F, Tran TN, Panettieri RA Jr

Pragmatic and Observational Research 2020, 11:77-90

Published Date: 16 July 2020

 

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