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Pragmatic and Observational Research
An international, peer reviewed, open access journal that publishes data from studies designed to reflect more closely medical interventions in real-world clinical practice compared with classical randomized controlled trials (RCTs).
Classical RCTs are designed to maximise internal validity and to establish an unequivocal cause-and-effect relationship between an intervention and an outcome. Classical RCT populations represent only minority groups of real-life patients and are thus limited in their extent. Complementary data from studies designed to reflect more closely the nature of real-world patients and medicines usage are required to inform guidelines and extrapolate research findings across the broad heterogeneous patient populations encountered in everyday clinical practice.
The journal publishes data from prospective and retrospective studies designed to evaluate outcomes associated with real-world clinical practice. Dissemination of this data and the techniques and approaches used to optimise real-world modeling allows outcome validation and improved standards and collaboration in this growing area of research.
This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE).
- Emerging Sources Citation Index (ESCI), from 2016
- PubMed and PubMed Central (Pragmat Obs Res)
- OAIster - the Open Access initiative
- 5 records -
Identification and Comparison of Patient Characteristics for Those Hospitalized with COVID-19 versus Influenza Using Machine Learning in a Commercially Insured US Population
Chen X, Wang Z, Bromfield SG, DeVries A, Pryor D, Willey V
Published Date: 23 April 2021
Published Date: 1 April 2021
Acceptability of Vaccination Against COVID-19 Among Healthcare Workers in the Democratic Republic of the Congo
Kabamba Nzaji M, Kabamba Ngombe L, Ngoie Mwamba G, Banza Ndala DB, Mbidi Miema J, Luhata Lungoyo C, Lora Mwimba B, Cikomola Mwana Bene A, Mukamba Musenga E
Published Date: 29 October 2020
Patients with Sore Throat: A Survey of Self-Management and Healthcare-Seeking Behavior in 13 Countries Worldwide
van der Velden AW, Sessa A, Altiner A, Pignatari ACC, Shephard A
Published Date: 10 September 2020
The CHRONICLE Study of US Adults with Subspecialist-Treated Severe Asthma: Objectives, Design, and Initial Results
Ambrose CS, Chipps BE, Moore WC, Soong W, Trevor J, Ledford DK, Carr WW, Lugogo N, Trudo F, Tran TN, Panettieri RA Jr
Published Date: 16 July 2020