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The interactions between hemostasis and resistance training: a review

Authors da Cunha Nascimento D, Ribeiro Neto F, Santos de Santana F, André Sousa Silva R, dos Santos-Neto L, Balsamo S

Received 15 December 2011

Accepted for publication 17 January 2012

Published 9 March 2012 Volume 2012:5 Pages 249—254

DOI https://doi.org/10.2147/IJGM.S29197

Review by Single-blind

Peer reviewer comments 3

Dahan da Cunha Nascimento1–3, Frederico Ribeiro Neto2, Frederico Santos de Santana1,2, Renato André Sousa da Silva1,4,5, Leopoldo dos Santos-Neto6,7, Sandor Balsamo1,2,6

1Physical Education Department, UNIEURO University Center, Brasília, DF, Brazil; 2GEPEEFS (Resistance training and Health Research Group), Brasília, DF, Brazil; 3Faculty of Physical Education, University of Brasília, Brasília, DF, Brazil; 4Center of Excellence in Medicine of Exercise (CEMEx) Brasília, DF, Brazil; 5Postgraduate Program on Physical Activity and Health, Catholic University of Brasília-UCB, Taguatinga DF, Brazil; 6Graduation Program – Medical Sciences Faculty, University of Brasília, Brasília, DF, Brazil; 7General Internal Medical Center – University Hospital Brasília, University of Brasília, Brasília, DF, Brazil

Abstract: Physical inactivity is considered a risk factor for cardiovascular disease and is strongly associated with changes in arterial structure. Regular physical activity and exercise contributes to the prevention of coronary artery disease. Therefore, cardiovascular and resistance training improve hemostatic parameters and promote a less thrombotic blood profile. This review highlights the studies, mechanisms, and outcomes relating to the effectiveness of resistance training on the process of hemostasis. The Pubmed, Scopus, Medline, Scielo, Lilacs, Ibecs, and Cochrane databases were used to locate the original articles. Seventeen studies were found during the research process. Of these, ten articles were excluded. Those protocols using a high volume of training for young adults showed a greater fibrinolytic response, and training protocols with intensities above 80% of 1 maximum repetition showed an increased platelet activity. In subjects with coronary artery disease, just one session of resistance training resulted in improvement in the fibrinolytic system (tissue plasminogen activator) without raising potential thrombotic markers.

Keywords: resistance training, blood coagulation, fibrinolysis

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