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Sex differences in predictors of ischemic stroke: current perspectives

Authors Samai A, Martin-Schild S

Received 30 March 2015

Accepted for publication 4 May 2015

Published 27 July 2015 Volume 2015:11 Pages 427—436


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Daniel A. Duprez

Alyana A Samai,1,2 Sheryl Martin-Schild1

1Department of Neurology, Stroke Program, Tulane University School of Medicine, 2Department of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, LA, USA

Abstract: Globally, stroke is a significant public health concern affecting more than 33 million individuals. Of growing importance are the differences between males and females in the predictors and overall risk of stroke. Given that women have a higher lifetime risk for stoke and account for more than half of all stroke deaths, sex-specific stroke risk factors merit investigation and may help target public health interventions. This review aims to discuss the current body of knowledge regarding sex-specific predictors of ischemic stroke including both modifiable and non-modifiable risk factors, as well as specific pathologies known to increase stroke risk.

Keywords: thrombosis, risk factors, sex, cerebral stroke

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