Pharmacogenomics and Personalized Medicine

Breaking Down the Intricacies of Catabolic Enzymes

Genetic polymorphisms are one way in which people vary from one another. While initial thoughts of "variance" might include a person’s physical features, it is well established that the body’s internal processes are also subject to differ dependent on a multitude of factors. This could include traits that follow them from birth, but also polypharmacy, or even diet. In line with the advances in modern medicine and genetic testing, research has started to explore the plethora of information linked to catabolic enzyme polymorphisms. This can involve specifying polymorphisms of interest, such as the Cytochrome P450 (CYP) family such as those including the location on the chromosome, possible allelic variations and the impact of these polymorphisms on their parent compound, metabolites or other molecules. This Collection explores the role of catabolic enzyme polymorphisms for a wide variety of disease areas, such as oncology, pulmonology, immunology, psychology, cardiology and more.