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Management of adult diabetic ketoacidosis

Authors Rosival V

Received 7 September 2014

Accepted for publication 8 September 2014

Published 28 November 2014 Volume 2014:7 Pages 571—573


Editor who approved publication: Professor Ming-Hui Zou

Viktor Rosival

SYNLAB, Department of Laboratory Medicine, Dérer's Hospital, Bratislava, Slovakia

In the article “Management of adult diabetic ketoacidosis” by Gosmanov et al1 there are some discrepancies with the literature. The authors write, “Insulin deficiency […] which underlie the pathophysiology of DKA [diabetic ketoacidosis]”, and on page 258, they write, “Insulin administration is essential in DKA treatment [...]”.1 Since the Nobel prize was awarded in 1977 to Rosalyn S Yalow for the development of new methods of biochemical analysis that make it possible to measure insulin concentration in human plasma, these methods have been used worldwide. In 1981, the monograph Diabetic Coma: Ketoacidotic and Hyperosmolar was published,2 and on page 67, Figure 6.3 has the names of 12 authors who have reported sufficient amounts of plasmatic insulin in patients with DKA.

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