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Fatigue in lung cancer patients: symptom burden and management of challenges

Authors Carnio S, Di Stefano R, Novello S

Received 16 January 2016

Accepted for publication 3 March 2016

Published 9 May 2016 Volume 2016:7 Pages 73—82


Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Wenting Wu

Peer reviewer comments 2

Editor who approved publication: Prof. Dr. Pan-Chyr Yang

Simona Carnio, Rosario Francesco Di Stefano, Silvia Novello

Oncology Department, University of Turin, AOU San Luigi, Orbassano, Italy

Abstract: Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) and symptoms that can affect patients' quality of life. In patients with LC, fatigue belongs to the symptom cluster of pain, depression, and insomnia, which are commonly observed simultaneously, but are typically treated as separate although they may have common biological mechanisms. The treatment of CRF remains one of the difficult areas in the oncology field: scarce evidence supports pharmacological therapies, while some interesting data arising indicates alternative remedies and physical exercise seem to be one of the most effective approaches for CRF at any stage of LC.

Keywords: fatigue, lung cancer, symptom cluster, quality of life

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