Back to Journals » Journal of Pain Research » Volume 12

Chronic Pain And Health-Related Quality Of Life In Women With Autism And/Or ADHD: A Prospective Longitudinal Study

Authors Asztély K, Kopp S, Gillberg C, Waern M, Bergman S

Received 16 April 2019

Accepted for publication 30 September 2019

Published 18 October 2019 Volume 2019:12 Pages 2925—2932


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Michael A Überall

Karin Asztély,1 Svenny Kopp,2 Christopher Gillberg,2 Margda Waern,3 Stefan Bergman1

1Department of Public Health and Community Medicine, Sahlgrenska Academy Institute of Medicine, Göteborg, Sweden; 2Gillberg Neuropsychiatric Centre, Sahlgrenska Academy Institute of Neuroscience and Physiology, Göteborg, Sweden; 3Department of Psychiatry and Neurochemistry, Sahlgrenska Academy Institute of Neuroscience and Physiology, Göteborg, Sweden

Correspondence: Karin Asztély
Department of Public Health and Community Medicine, Sahlgrenska Academy Institute of Medicine, Box 454, Göteborg S-405 30, Sweden
Tel +46 (0)700 207 580
Fax +46 (0)31 778 17 04

Purpose: To investigate the prevalence of chronic pain and its association with health-related quality of life (HRQoL) in a group of women, diagnosed with autism spectrum disorder (ASD) and/or attention deficit hyperactive disorder (ADHD) in childhood.
Patients and methods: Prospective longitudinal 16–19 years follow-up study of 100 Swedish females diagnosed with ASD and/or ADHD in childhood/adolescence. Seventy-seven of the women were included in the current sub-study, using validated measures of pain perception and quality of life.
Results: A large majority of the women (76.6%) reported chronic pain. HRQoL was low overall and lower still for those reporting chronic pain. Women with ADHD who had ongoing treatment with stimulants reported a significant lower prevalence of chronic widespread pain (CWP) than those not treated.
Conclusion: Comorbidity with chronic pain is common in women with ASD and/or ADHD and important to address in the clinic since it is associated with an already low HRQoL. Treatment for ADHD might reduce the pain in some cases.

Keywords: female, girls, attention deficit disorder, autism spectrum disorder, widespread pain, stimulants

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]