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Chronic Pain And Health-Related Quality Of Life In Women With Autism And/Or ADHD: A Prospective Longitudinal Study

Authors Asztély K, Kopp S, Gillberg C, Waern M, Bergman S

Received 16 April 2019

Accepted for publication 30 September 2019

Published 18 October 2019 Volume 2019:12 Pages 2925—2932

DOI https://doi.org/10.2147/JPR.S212422

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Nicola Ludin

Peer reviewer comments 2

Editor who approved publication: Dr Michael Ueberall


Karin Asztély,1 Svenny Kopp,2 Christopher Gillberg,2 Margda Waern,3 Stefan Bergman1

1Department of Public Health and Community Medicine, Sahlgrenska Academy Institute of Medicine, Göteborg, Sweden; 2Gillberg Neuropsychiatric Centre, Sahlgrenska Academy Institute of Neuroscience and Physiology, Göteborg, Sweden; 3Department of Psychiatry and Neurochemistry, Sahlgrenska Academy Institute of Neuroscience and Physiology, Göteborg, Sweden

Correspondence: Karin Asztély
Department of Public Health and Community Medicine, Sahlgrenska Academy Institute of Medicine, Box 454, Göteborg S-405 30, Sweden
Tel +46 (0)700 207 580
Fax +46 (0)31 778 17 04
Email Karin.susanna.asztely@vgregion.se

Purpose: To investigate the prevalence of chronic pain and its association with health-related quality of life (HRQoL) in a group of women, diagnosed with autism spectrum disorder (ASD) and/or attention deficit hyperactive disorder (ADHD) in childhood.
Patients and methods: Prospective longitudinal 16–19 years follow-up study of 100 Swedish females diagnosed with ASD and/or ADHD in childhood/adolescence. Seventy-seven of the women were included in the current sub-study, using validated measures of pain perception and quality of life.
Results: A large majority of the women (76.6%) reported chronic pain. HRQoL was low overall and lower still for those reporting chronic pain. Women with ADHD who had ongoing treatment with stimulants reported a significant lower prevalence of chronic widespread pain (CWP) than those not treated.
Conclusion: Comorbidity with chronic pain is common in women with ASD and/or ADHD and important to address in the clinic since it is associated with an already low HRQoL. Treatment for ADHD might reduce the pain in some cases.

Keywords: female, girls, attention deficit disorder, autism spectrum disorder, widespread pain, stimulants

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