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Papers published by Professor Nicolas Roche:
Response to the Letter to the Editor by Zambelli et al for In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients With COPD Using Functional Respiratory Imaging [Response To Letter]
Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J
International Journal of Chronic Obstructive Pulmonary Disease 2026, 21:597524
Published Date: 3 March 2026
Economic Burden of Uncontrolled COPD Under Triple Therapy: A Population-Based Study
Molinari N, Roche N, Vataire AL, Perrier S, Pagès N, Panes A, Schmidt A, Bourdin A, Watier L
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:3295-3304
Published Date: 24 September 2025
Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM
Del Giacco S, Canonica GW, Agache I, Price D, Roche N, Schunemann H, Allan K, Ansotegui I, Barbaglia S, Bernstein JA, Bonini M, Bosnic-Anticevich S, Bousquet J, Braido F, Carter V, Chong-Neto HJ, Di Bona D, Fletton K, Gonzalez Diaz S, Ayyar Gupta V, Hubbard R, Iaccarino J, Eguiluz-Gracia I, Jacomelli C, Kocks J, Krishnan J, Mahler V, Morais-Almeida M, Moreles D, Muti P, Palkonen S, Papadopoulos NG, Pawankar R, Reeb C, Reddel H, Rojo I, Ryan D, Sodhi L, Torres M, Winders T, Wilson KC
Pragmatic and Observational Research 2025, 16:169-177
Published Date: 11 September 2025
In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients with COPD Using Functional Respiratory Imaging
Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:2103-2116
Published Date: 27 June 2025
Single-Inhaler Triple Therapy in Primary Care Across Europe: Expert Panel Consensus on the Consequences of Payer-Driven Access Rules and Call to Action
Di Marco F, Shahaj O, Valipour A, Legrand B, Jommi C, Micheletto C, Vogelmeier CF, Freeman D, Kocks JWH, Alves L, Rubio MC, Peché R, Palkonen Snr S, Winders T, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2025, 20:1595-1612
Published Date: 22 May 2025
Improving Assessment of Adherence Behaviors and Drivers: Targeted Literature Review and Concept Elicitation Interviews in Multiple Countries and Disease Populations
Bentley S, Exall E, Morgan L, Roche N, Khunti K, Rossom R, Piercy J, Arbuckle R, Higgins VS
Patient Preference and Adherence 2024, 18:1231-1242
Published Date: 17 June 2024
Risk of Pneumonia in Patients with COPD Initiating Fixed Dose Inhaled Corticosteroid (ICS) / Long-Acting Bronchodilator (LABD) Formulations Containing Extrafine Beclometasone Dipropionate versus Patients Initiating LABD Without ICS
Price D, Henley W, Cançado JED, Fabbri LM, Kerstjens HA, Papi A, Roche N, Şen E, Singh D, Vogelmeier CF, Nudo E, Carter V, Skinner D, Vella R, Soriano JB, Kots M, Georges G
Pragmatic and Observational Research 2024, 15:1-16
Published Date: 20 January 2024
Qualitative Interviews to Support Development and Cognitive Debriefing of the Adelphi Adherence Questionnaire (ADAQ©): A Patient-Reported Measure of Medication Adherence Developed for Use in a Range of Diseases, Treatment Modalities, and Countries
Bentley S, Morgan L, Exall E, Arbuckle R, Rossom RC, Roche N, Khunti K, Higgins V, Piercy J
Patient Preference and Adherence 2022, 16:2579-2592
Published Date: 15 September 2022
Interclass Difference in Pneumonia Risk in COPD Patients Initiating Fixed Dose Inhaled Treatment Containing Extrafine Particle Beclometasone versus Fine Particle Fluticasone [Corrigendum]
Price DB, Henley W, Cançado JED, Fabbri LM, Kerstjens HA, Papi A, Roche N, Şen E, Singh D, Vogelmeier CF, Barille S, Nudo E, Carter V, Skinner D, Vella R, Georges G
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:489-490
Published Date: 7 March 2022
Interclass Difference in Pneumonia Risk in COPD Patients Initiating Fixed Dose Inhaled Treatment Containing Extrafine Particle Beclometasone versus Fine Particle Fluticasone
Price DB, Henley W, Cançado JED, Fabbri LM, Kerstjens HA, Papi A, Roche N, Şen E, Singh D, Vogelmeier CF, Barille S, Nudo E, Carter V, Skinner D, Vella R, Georges G
International Journal of Chronic Obstructive Pulmonary Disease 2022, 17:355-370
Published Date: 15 February 2022
Impact of Socioeconomic Status on Adult Patients with Asthma: A Population-Based Cohort Study from UK Primary Care
Busby J, Price D, Al-Lehebi R, Bosnic-Anticevich S, van Boven JFM, Emmanuel B, FitzGerald JM, Gaga M, Hansen S, Hew M, Iwanaga T, Larenas Linnemann D, Mahboub B, Mitchell P, Morrone D, Pham J, Porsbjerg C, Roche N, Wang E, Eleangovan N, Heaney LG
Journal of Asthma and Allergy 2021, 14:1375-1388
Published Date: 10 November 2021
Inhaled Dual Phosphodiesterase 3/4 Inhibitors for the Treatment of Patients with COPD: A Short Review
Martin C, Burgel PR, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:2363-2373
Published Date: 16 August 2021
Maximizing Adherence and Gaining New Information For Your Chronic Obstructive Pulmonary Disease (MAGNIFY COPD): Study Protocol for the Pragmatic, Cluster Randomized Trial Evaluating the Impact of Dual Bronchodilator with Add-On Sensor and Electronic Monitoring on Clinical Outcomes
Price D, Jones R, Pfister P, Cao H, Carter V, Kemppinen A, Holzhauer B, Kaplan A, Clark A, Halpin DMG, Pinnock H, Chalmers JD, van Boven JF, Beeh KM, Kostikas K, Roche N, Usmani OA, Mastoridis P
Pragmatic and Observational Research 2021, 12:25-35
Published Date: 24 May 2021
Burden and Characteristics of Severe Chronic Hypoxemia in a Real-World Cohort of Subjects with COPD
Zysman M, Deslee G, Perez T, Burgel PR, Le Rouzic O, Brinchault-Rabin G, Nesme-Meyer P, Court-Fortune I, Jebrak G, Chanez P, Caillaud D, Paillasseur JL, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:1275-1284
Published Date: 10 May 2021
Consistent Pulmonary Drug Delivery with Whole Lung Deposition Using the Aerosphere Inhaler: A Review of the Evidence
Usmani OS, Roche N, Jenkins M, Stjepanovic N, Mack P, De Backer W
International Journal of Chronic Obstructive Pulmonary Disease 2021, 16:113-124
Published Date: 18 January 2021
Extrafine Beclometasone Dipropionate/Formoterol Fumarate vs Double Bronchodilation Therapy in Patients with COPD: A Historical Real-World Non-Inferiority Study
Voorham J, Baldi S, Santoro L, Kerkhof M, Contoli M, Fabbri LM, Kerstjens HAM, Luis López-Campos J, Roche N, Singh D, Vogelmeier CF, Price DB
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:2739-2750
Published Date: 29 October 2020
In Patients with Mild-to-Moderate COPD, Tobacco Smoking, and Not COPD, Is Associated with a Higher Risk of Cardiovascular Comorbidity
Soumagne T, Guillien A, Roche N, Annesi-Maesano I, Andujar P, Laurent L, Jouneau S, Botebol M, Laplante JJ, Dalphin JC, Degano B
International Journal of Chronic Obstructive Pulmonary Disease 2020, 15:1545-1555
Published Date: 1 July 2020
Dual versus triple therapy in patients hospitalized for COPD in France: a claims data study
Dalon F, Roche N, Belhassen M, Nolin M, Pegliasco H, Deslée G, Housset B, Devillier P, Van Ganse E
International Journal of Chronic Obstructive Pulmonary Disease 2019, 14:1839-1854
Published Date: 20 August 2019
Predictors in routine practice of 6-min walking distance and oxygen desaturation in patients with COPD: impact of comorbidities
Perez T, Deslée G, Burgel PR, Caillaud D, Le Rouzic O, Zysman M, Escamilla R, Jebrak G, Chanez P, Court-Fortune I, Brinchault-Rabin G, Nesme-Meyer P, Paillasseur JL, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2019, 14:1399-1410
Published Date: 2 July 2019
Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study
Vogelmeier CF, Chapman KR, Miravitlles M, Roche N, Vestbo J, Thach C, Banerji D, Fogel R, Patalano F, Olsson P, Kostikas K, Wedzicha JA
International Journal of Chronic Obstructive Pulmonary Disease 2018, 13:1125-1134
Published Date: 10 April 2018
Pneumococcal vaccination and chronic respiratory diseases
Froes F, Roche N, Blasi F
International Journal of Chronic Obstructive Pulmonary Disease 2017, 12:3457-3468
Published Date: 5 December 2017
Relationship between blood eosinophils, clinical characteristics, and mortality in patients with COPD
Zysman M, Deslee G, Caillaud D, Chanez P, Escamilla R, Court-Fortune I, Nesme-Meyer P, Perez T, Paillasseur JL, Pinet C, Jebrak G, Roche N, Burgel PR
International Journal of Chronic Obstructive Pulmonary Disease 2017, 12:1819-1824
Published Date: 20 June 2017
Mid-regional pro-adrenomedullin and copeptin to predict short-term prognosis of COPD exacerbations: a multicenter prospective blinded study
Dres M, Hausfater P, Foissac F, Bernard M, Joly LM, Sebbane M, Philippon AL, Gil-Jardiné C, Schmidt J, Maignan M, Treluyer JM, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2017, 12:1047-1056
Published Date: 31 March 2017
An evaluation of exact matching and propensity score methods as applied in a comparative effectiveness study of inhaled corticosteroids in asthma
Burden A, Roche N, Miglio C, Hillyer EV, Postma DS, Herings RMC, Overbeek JA, Khalid JM, van Eickels D, Price DB
Pragmatic and Observational Research 2017, 8:15-30
Published Date: 22 March 2017
Impact of current cough on health-related quality of life in patients with COPD
Deslee G, Burgel PR, Escamilla R, Chanez P, Court-Fortune I, Nesme-Meyer P, Brinchault-Rabin G, Perez T, Jebrak G, Caillaud D, Paillasseur JL, Roche N
International Journal of Chronic Obstructive Pulmonary Disease 2016, 11:2091-2097
Published Date: 13 September 2016