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Women taking the “blue pill” (sildenafil citrate): such a big deal?

Authors Lo Monte G, Graziano A, Piva I, Marci R

Received 16 July 2014

Accepted for publication 18 August 2014

Published 7 November 2014 Volume 2014:8 Pages 2251—2254

DOI https://doi.org/10.2147/DDDT.S71227

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 6

Editor who approved publication: Professor Shu-Feng Zhou


Giuseppe Lo Monte, Angela Graziano, Isabella Piva, Roberto Marci

Department of Morphology, Surgery, and Experimental Medicine, University of Ferrara, Ferrara, Italy

Abstract: For years, phosphodiesterase type 5 inhibitors have been used for the treatment of erectile dysfunctions. Due to the similarities between male and female sexual response, several studies have assessed the effects of sildenafil citrate (Viagra®) in women affected by female sexual arousal disorder. The results are still conflicting and the drug is not devoid of adverse effects. Furthermore, female sexual arousal disorder is a heterogeneous condition whose underlying causes are difficult to diagnose and appropriate treatment requires a thorough sexual, psychological, and medical history along with specialist consultations. The clinician should pursue a global approach to the patient with sexual difficulties, while non-hormonal treatment such as phosphodiesterase type 5 inhibitors (ie, sildenafil citrate) should be kept as the last option.

Keywords: phosphodiesterase type 5 inhibitors, female sexual arousal disorder (FSAD), sildenafil citrate

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