Waist–Calf Circumference Ratio Is an Independent Risk Factor of HRQoL in Centenarians
Received 17 September 2019
Accepted for publication 15 January 2020
Published 4 February 2020 Volume 2020:13 Pages 277—287
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 2
Editor who approved publication: Prof. Dr. Juei-Tang Cheng
Shanshan Yang, 1, 2,* Miao Liu, 1,* Shengshu Wang, 1 Wangping Jia, 1 Ke Han, 1 Yao He 1
1Institute of Geriatrics, State Key Laboratory of Kidney Disease, Beijing Key Laboratory of Aging and Geriatrics, The 2nd Clinical Center, Chinese PLA General Hospital, Beijing 100853, People’s Republic of China; 2Department of Disease Control, Northern Military Area Center for Disease Control and Prevention, Jinan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Yao He
Institute of Geriatrics State Key Laboratory of Kidney Disease, Beijing Key Laboratory of Aging and Geriatrics, The 2nd Clinical Center, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, People’s Republic of China
Purpose: To analyze the associations between waist circumference (WC), body mass index (BMI), waist–hip ratio (WHR), waist–height ratio (WHtR), calf circumference, waist-calf circumference ratio (WCR), and quality of life in Hainan centenarians.
Patients and Methods: A total of 1002 centenarians in Hainan were selected by a full sample survey. The EQ-5D visual analogue scale (EQ-5D-VAS) was used to investigate the quality of life. Restricted cubic splines were used to analyze and visualize the linear relationships.
Results: After adjustment, the standard β values for BMI, WC, WHR, WHtR, calf circumference, and WCR associated with EQ-5D score were 0.101, 0.126, − 0.018, 0.100, 0.302, and − 0.219, respectively; all associations except for WHR were significant (P < 0.01). With increasing BMI, WC, and calf circumference, the risk of EQ-5D score < 1 decreased (odds ratios [ORs] 0.91 [95% confidence interval (CI): 0.86– 0.97), 0.97 [95% CI: 0.95– 0.99], and 0.87 [95% CI: 0.82– 0.92] after adjustment, respectively). With increasing WCR, the risk also increased (OR 2.70 [95% CI: 1.54– 4.75]).
Conclusion: After excluding nutritional and muscle retention factors, fat central distribution negatively impacted the health-related quality of life of the oldest old population.
Keywords: centenarians, waist–calf circumference ratio, quality of life, obesity