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Update to: Application of Bayesian decision-making to laboratory testing for Lyme disease and comparison with testing for HIV

Authors Cook MJ, Puri BK

Received 29 June 2017

Accepted for publication 17 August 2017

Published 11 September 2017 Volume 2017:10 Pages 291—292

DOI https://doi.org/10.2147/IJGM.S145134

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Michael J Cook,1 Basant K Puri2

1Independent researcher, Highcliffe, UK; 2Department of Medicine, Hammersmith Hospital, Imperial College London, London, UK

In our recent Bayesian analysis paper, false-negative results were compared between Lyme disease and HIV using a recommended test algorithm.1 When the two-tier test methodology for Lyme disease was compared with HIV two-stage testing, false negatives could be more than 500 times higher for Lyme disease testing.


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