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Tools for visualization and analysis of molecular networks, pathways, and -omics data

Authors Villaveces JM, Koti P, Habermann BH

Received 27 January 2015

Accepted for publication 1 April 2015

Published 4 June 2015 Volume 2015:8 Pages 11—22

DOI https://doi.org/10.2147/AABC.S63534

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Juan Fernandez-Recio

Jose M Villaveces, Prasanna Koti, Bianca H Habermann

Max Planck Institute of Biochemistry, Research Group Computational Biology, Martinsried, Germany

Abstract: Biological pathways have become the standard way to represent the coordinated reactions and actions of a series of molecules in a cell. A series of interconnected pathways is referred to as a biological network, which denotes a more holistic view on the entanglement of cellular reactions. Biological pathways and networks are not only an appropriate approach to visualize molecular reactions. They have also become one leading method in -omics data analysis and visualization. Here, we review a set of pathway and network visualization and analysis methods and take a look at potential future developments in the field.

Keywords: biological networks, reactions, proteins, genes, signaling, protein-protein interactions, organisms

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