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The role of joint distraction in the treatment of knee osteoarthritis: a systematic review and quantitative analysis

Authors Goh EL, Lou WCN, Chidambaram S, Ma S

Received 4 April 2019

Accepted for publication 10 July 2019

Published 7 August 2019 Volume 2019:11 Pages 79—92

DOI https://doi.org/10.2147/ORR.S211060

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Melinda Thomas

Peer reviewer comments 2

Editor who approved publication: Professor Clark Hung


En Lin Goh,1 Winston Choong Ngan Lou,2 Swathikan Chidambaram,1 Shaocheng Ma3

1Oxford University Clinical Academic Graduate School, Medical Sciences Division, University of Oxford, Oxford, UK; 2Faculty of Medicine, Imperial College London, London, UK; 3City and Guilds Building, Imperial College London, London, UK

Introduction: Knee osteoarthritis is a major cause of pain and disability for which joint distraction is a potential treatment to delay the need for knee arthroplasty. This systematic review aims to assess the short- and long-term clinical and structural outcomes following knee joint distraction (KJD).
Methods: MEDLINE, EMBASE, Scopus, and Web of Science databases were searched from the date of inception to 26th June 2019. Clinical studies investigating joint distraction for knee osteoarthritis with outcomes including ∆WOMAC index, ∆VAS pain score, and ∆joint space width were included. The review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) – CRD42018087032.
Results: Nine studies comprising a total of 507 patients were included. There were four randomized controlled trials (RCTs), five open prospective cohort studies, and one case series. Overall, there were significant improvements in WOMAC index, VAS pain score and joint space width following KJD, which persisted up to 9 years. KJD also demonstrated comparable clinical outcomes with high tibial osteotomy and total knee arthroplasty.
Conclusion: There is moderate quality evidence supporting the beneficial outcomes of joint distraction for knee osteoarthritis. Larger RCTs with longer follow-up (>1 year) are necessary to establish the true effect size of this procedure.

Keywords: osteoarthritis, knee joint distraction, total knee arthroplasty, high tibial osteotomy, clinical outcomes, structural outcomes


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