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The etiology, evaluation, and management of plantar fibromatosis

Authors Young JR, Sternbach S, Willinger M, Hutchinson ID, Rosenbaum AJ

Received 31 July 2018

Accepted for publication 28 November 2018

Published 17 December 2018 Volume 2019:11 Pages 1—7

DOI https://doi.org/10.2147/ORR.S154289

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Professor Clark Hung


Joseph R Young, Sarah Sternbach, Max Willinger, Ian D Hutchinson, Andrew J Rosenbaum

Albany Medical College Division of Orthopaedic Surgery, Albany, NY, USA

Abstract: Plantar fibromatosis (Ledderhose disease) is a rare, benign, hyperproliferative fibrous tissue disorder resulting in the formation of nodules along the plantar fascia. This condition can be locally aggressive, and often results in pain, functional disability, and decreased quality of life. Diagnosis is primarily clinical, but MRI and ultrasound are useful confirmatory adjuncts. Given the benign nature of this condition, treatment has historically involved symptomatic management. A multitude of conservative treatment strategies supported by varying levels of evidence have been described mostly in small-scale trials. These therapies include steroid injections, verapamil, radiation therapy, extracorporeal shock wave therapy, tamoxifen, and collagenase. When conservative measures fail, surgical removal of fibromas and adjacent plantar fascia is often done, although recurrence is common. This review aims to provide a broad overview of the clinical features of this disease as well as the current treatment strategies being employed in the management of this condition.

Keywords: plantar fibromatosis, plantar fascia, Ledderhose disease

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