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Six Years Trend Analysis of Tuberculosis in Northwestern Tigrai, Ethiopia; 2019: A Retrospective Study

Authors Negash H, Legese H, Adhanom G, Mardu F, Tesfay K, Gebreslasie Gebremeskel S, Berhe B

Received 22 November 2019

Accepted for publication 13 February 2020

Published 24 February 2020 Volume 2020:13 Pages 643—649

DOI https://doi.org/10.2147/IDR.S239717

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Professor Suresh Antony


Hadush Negash,1 Haftom Legese,1 Gebre Adhanom,1 Fitsum Mardu,2 Kebede Tesfay,2 Senait Gebreslasie Gebremeskel,3 Brhane Berhe2

1Unit of Medical Microbiology, Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Adigrat University, Tigrai, Ethiopia; 2Unit of Medical Parasitology, Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Adigrat University, Tigrai, Ethiopia; 3Unit of Pediatrics and Child Health, Department of Midwifery, College of Medicine and Health Sciences, Adigrat University, Tigrai, Ethiopia

Correspondence: Hadush Negash Email hadunegash@gmail.com

Background: Ethiopia is one of the 22 high tuberculosis burden countries. In our country. there are limited published data to show the trend analysis of tuberculosis. Hence, we designed this trend analysis to fill the information gap in our study area. Institutional based retrospective cross-sectional study was employed from 2013 to 2018 to determine the trend analysis of tuberculosis among tuberculosis presumptive clients in Northwestern Tigrai. We have used a standard checklist to extract the data. There were some missing data from the logbooks which are then excluded from the analysis.
Results: A total of 7793 tuberculosis presumptive clients were requested for laboratory diagnosis of which about 7639 results had a valid result for X-pert MTB/Rif assay. The overall detection rate of tuberculosis was found to be 9.9% (756/7639). Of the total tuberculosis cases, 8.7 % (66/756) were rifampicin-resistant. The trend of tuberculosis across the six years was fluctuating with a declining trend in the recent three years. HIV infection and being presumptive to drug resistance were associated with tuberculosis detection.
Conclusion: Although there was a cumulative declining trend of tuberculosis within the last six years, prevention and control strategies still need to be improved to achieve the stop tuberculosis strategy. To create a world free of tuberculosis, there should be quality service provision regarding tuberculosis case detection and treatment.

Keywords: X-pert MTB/Rif assay, retrospective, Northwestern Tigrai, trend, tuberculosis

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