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Seroprevalence of Helicobacter pylori Infection and Associated Factors Among Adult Dyspeptic Patients in Public Health Facilities, Mizan Aman Town, Southwest, Ethiopia: Institutional-Based Cross-Sectional Study

Authors Belay AS, Abateneh DD, Yehualashet SS

Received 23 July 2020

Accepted for publication 22 August 2020

Published 10 September 2020 Volume 2020:13 Pages 577—585

DOI https://doi.org/10.2147/IJGM.S273523

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Alemayehu Sayih Belay,1 Dejene Derseh Abateneh,1,2 Sisay Shewasinad Yehualashet1,3

1Mizan Tepi University, College of Health Sciences, Department of Nursing, Mizan Aman, Ethiopia; 2Kotebe Metropolitan University, Menelik II College of Medicine and Health Sciences, Department of Medical Laboratory Sciences, Addis Ababa, Ethiopia; 3Debre Berhan University, Institute of Health Sciences, Debre Berhan, Ethiopia

Correspondence: Alemayehu Sayih Belay
Mizan Tepi University, College of Health Sciences, Department of Nursing, P.O. Box: 260, Mizan Teferi, Ethiopia
Tel +251-911669861
Email Alex.sayihalem2018@gmail.com

Background: Helicobacter pylori infection is a public health problem associated with chronic gastritis, peptic ulcer, and gastric cancer. It is endemic in developing countries like Ethiopia. This study was aimed to assess seroprevalence of H. pylori infection and associated factors among adults’ dyspeptic patients in public health facilities of Mizan Aman Town, Southwest Ethiopia.
Methods: Cross-sectional study was conducted in public health facilities of Mizan Aman Town, from April 1, 2018, to June 30, 2018. A total of 208 adult dyspeptic patients were included in the study. A structured questionnaire was used to collect data. Serum was tested for anti-H. pylori antibody using a commercial test strip. Data were entered using Epi info 6.04 and exported to SPSS 21 for analysis. Bivariate and multivariate logistic regression was employed and OR with 95% CI was retrieved. P-value of less than 0.05 was considered as statistically significant.
Results: A total of 208 participants were interviewed. The mean age of respondents was 31.70 (SD ± 9.123) years. Seroprevalence of H. pylori infection was 89 (42.8%). Presence of domestic animals (AOR = 13.33, 95% CI = (2.203– 80.692)), sources of drinking water (AOR = 0.011, 95% CI = (0.001– 0.110)), toilet type (AOR = 11.236, 95% CI = (1.921– 65.73)), shared beds with siblings (AOR = 7.775, 95% CI = (1.676– 36.082)), family size (AOR = 0.015, 95% CI = (0.003, 0.089)), storing and reusing water (AOR =0.014, 95% CI = (0.002– 0.103)) and occupational status (AOR = 23.33, 95% CI = (2.034– 67.661)) were variables significantly associated with seroprevalence of H. pylori.
Conclusion: Seroprevalence of H. pylori infection is relatively high in Ethiopia. Family size, shared bed, presences of domestic animals, storage and reuse of water, toilet type, sources of drinking water, and occupation were significant factors associated with H. pylori infection. The possible identified modifiable risk factors should be addressed through effective health education.

Keywords: H. pylori, seroprevalence, dyspepsia, Ethiopia

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