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Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
Authors Thohar Arifin M, Muttaqin Z, Bakhtiar Y, Andar E, Priambada D, Kurnia H, Risdianto A, Tsaniadi K, Kusnarto G, Bunyamin J
Received 28 January 2020
Accepted for publication 6 March 2020
Published 31 March 2020 Volume 2020:13 Pages 105—110
DOI https://doi.org/10.2147/IJGM.S247438
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Muhamad Thohar Arifin, Zainal Muttaqin, Yuriz Bakhtiar, Erie Andar, Dody Priambada, Happy Kurnia, Ajid Risdianto, Krisna Tsaniadi, Gunadi Kusnarto, Jacob Bunyamin
Department of Neurosurgery, Faculty of Medicine, Diponegoro University, Kariadi Hospital, Semarang, Indonesia
Correspondence: Muhamad Thohar Arifin Email thohar@fk.undip.ac.id
Introduction: Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus is not feasible. We are presenting our experience in treating intractable epilepsy patients by CCT procedures.
Methods: We observed 16 patients who underwent callosotomy (male to female ratio 7:9; adult to pediatric ratio 3:13). Initial seizure frequency was reported ranged from 1 to 2 attacks daily to very often (more than 20 episodes daily).
Results: Our observation showed that among patients with drop attacks, complete and > 90% seizure freedom was reported by 4 and 6 of 13 patients, respectively (76.9% combined).
Conclusion: Our observation showed that corpus callosotomy yielded good outcome in patients with intractable epilepsy in Indonesia. Our observation showed total callosotomy achieved complete seizure freedom better compared to partial callosotomy patients.
Keywords: corpus callosotomy, drop attacks, Indonesia
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