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Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome

Authors Thohar Arifin M, Muttaqin Z, Bakhtiar Y, Andar E, Priambada D, Kurnia H, Risdianto A, Tsaniadi K, Kusnarto G, Bunyamin J

Received 28 January 2020

Accepted for publication 6 March 2020

Published 31 March 2020 Volume 2020:13 Pages 105—110

DOI https://doi.org/10.2147/IJGM.S247438

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Muhamad Thohar Arifin, Zainal Muttaqin, Yuriz Bakhtiar, Erie Andar, Dody Priambada, Happy Kurnia, Ajid Risdianto, Krisna Tsaniadi, Gunadi Kusnarto, Jacob Bunyamin

Department of Neurosurgery, Faculty of Medicine, Diponegoro University, Kariadi Hospital, Semarang, Indonesia

Correspondence: Muhamad Thohar Arifin Email thohar@fk.undip.ac.id

Introduction: Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus is not feasible. We are presenting our experience in treating intractable epilepsy patients by CCT procedures.
Methods: We observed 16 patients who underwent callosotomy (male to female ratio 7:9; adult to pediatric ratio 3:13). Initial seizure frequency was reported ranged from 1 to 2 attacks daily to very often (more than 20 episodes daily).
Results: Our observation showed that among patients with drop attacks, complete and > 90% seizure freedom was reported by 4 and 6 of 13 patients, respectively (76.9% combined).
Conclusion: Our observation showed that corpus callosotomy yielded good outcome in patients with intractable epilepsy in Indonesia. Our observation showed total callosotomy achieved complete seizure freedom better compared to partial callosotomy patients.

Keywords: corpus callosotomy, drop attacks, Indonesia

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