Therapeutic Effects of Tyroserleutide on Lung Metastasis of Human Hepatocellular Carcinoma SK-HEP-1 and Its Mechanism Affecting ICAM-1 and MMP-2 and -9 [Retraction]

Che X, Lu R, Fu Z, et al. Drug Des Devel Ther. 2018;12:3357–3368.

At the authors request, the Editor and Publisher of Drug Design, Development and Therapy wish to retract the published article. The authors became aware of concerns relating to the alleged duplication of images in Figure 7. Specifically,

• Figure 7B, Medium (100x), appears to have been duplicated with the same image for Figure 7E, YSL 0.4 mg/ml (100x), which has been flipped.

While some original data was still available, the authors were unable to retrieve all of it in a satisfactory manner. In addition, some to the key cellular extraction material had not been well preserved. While the authors were still confident in the overall findings described in the article, to maintain the integrity of the scientific publication record, they decided it appropriate to request a retraction rather than pursue a corrigendum. The editor agreed with decision and approved the authors retraction request.

We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.